ferrous gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4491	299-29-6

Description:

Molecule	Description
Synonyms: sodium ferric gluconate complex ferrous gluconate iron gluconate ferroglyconicum glucoferron	iron important in this cpd; RN given refers to ferrous cpd Molecular weight: 446.14 Formula: C12H22FeO14 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 265.04 ALOGS: ROTB: None

Molecule

Description

Synonyms:

sodium ferric gluconate complex
ferrous gluconate
iron gluconate
ferroglyconicum
glucoferron

iron important in this cpd; RN given refers to ferrous cpd

Molecular weight: 446.14
Formula: C12H22FeO14
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 265.04
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
0.20	g	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Feb. 18, 1999	FDA	SANOFI AVENTIS US

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Reversible airways obstruction	216.94	16.33	58	17589	1784	63469591
Vital capacity decreased	211.05	16.33	56	17591	1672	63469703
Sputum culture positive	198.50	16.33	56	17591	2111	63469264
Bronchial secretion retention	184.86	16.33	56	17591	2717	63468658
Presbyacusis	153.72	16.33	49	17598	2816	63468559
Pleural fibrosis	144.47	16.33	49	17598	3423	63467952
Pleural thickening	129.11	16.33	43	17604	2840	63468535
Deafness neurosensory	128.43	16.33	49	17598	4806	63466569
Eosinophil count increased	125.12	16.33	61	17586	10867	63460508
Blood magnesium increased	119.08	16.33	41	17606	2997	63468378

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	453.82	21.46	141	8491	8460	34939839
Appendicitis	378.73	21.46	141	8491	14666	34933633
Cardiogenic shock	305.08	21.46	143	8489	26475	34921824
Stress	302.15	21.46	148	8484	30199	34918100
Ascites	245.28	21.46	149	8483	46422	34901877
Abdominal distension	223.67	21.46	153	8479	58339	34889960
Ventricular fibrillation	207.75	21.46	105	8527	22849	34925450
Blood phosphorus increased	188.02	21.46	71	8561	7650	34940649
Multiple organ dysfunction syndrome	182.67	21.46	151	8481	76415	34871884
Hyponatraemia	174.56	21.46	152	8480	82539	34865760

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	421.83	15.24	140	23970	8411	79711867
Appendicitis	301.10	15.24	140	23970	20654	79699624
Cardiogenic shock	216.58	15.24	143	23967	41771	79678507
Vital capacity decreased	189.81	15.24	53	24057	1763	79718515
Reversible airways obstruction	189.15	15.24	55	24055	2121	79718157
Stress	169.43	15.24	161	23949	79451	79640827
Ascites	168.84	15.24	157	23953	75405	79644873
Blood phosphorus increased	157.03	15.24	72	24038	10275	79710003
Ventricular fibrillation	153.06	15.24	104	24006	31822	79688456
Sputum culture positive	151.53	15.24	53	24057	3728	79716550

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FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

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Source	Code	Description
ATC	B03AA03	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron bivalent, oral preparations
ATC	B03AD05	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron in combination with folic acid
FDA CS	M0011718	Iron
FDA EPC	N0000177913	Parenteral Iron Replacement
MeSH PA	D006397	Hematinics
MeSH PA	D006401	Hematologic Agents

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Drug Use | Suggest Off label Use Form| |View source of the data|

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Disease	Relation	SNOMED_ID	DOID
Anemia of prematurity	indication	47100003	DOID:11243
Iron deficiency anemia	indication	87522002
Peptic ulcer	contraindication	13200003	DOID:750
Gastroenteritis	contraindication	25374005	DOID:2326
Hemosiderosis	contraindication	39011001	DOID:12119
Hemolytic anemia	contraindication	61261009	DOID:583
Ulcerative colitis	contraindication	64766004	DOID:8577
Diverticular disease	contraindication	397881000
Hemochromatosis	contraindication	399187006	DOID:2352
Repeated Blood Transfusions	contraindication

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🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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ID	Source
000834	NDDF
007777	NDDF
116130008	SNOMEDCT_US
189358	MMSL
23616740	PUBCHEM_CID
24942	RXNORM
26736008	SNOMEDCT_US
34089-81-1	SECONDARY_CAS_RN
387147005	SNOMEDCT_US
4017678	VANDF

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Pharmaceutical products:

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Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
BioFerr 90	HUMAN PRESCRIPTION DRUG LABEL	6	44523-732	TABLET, FILM COATED	13.20 mg	ORAL	Unapproved drug other	20 sections
CitraNatal 90 DHA	HUMAN PRESCRIPTION DRUG LABEL	16	0178-0821	TABLET	5 mg	ORAL	unapproved drug other	11 sections
CitraNatal 90 DHA	HUMAN PRESCRIPTION DRUG LABEL	16	0178-0821	TABLET	5 mg	ORAL	unapproved drug other	11 sections
CitraNatal Bloom	HUMAN PRESCRIPTION DRUG LABEL	6	0178-0813	TABLET, FILM COATED	13.20 mg	ORAL	unapproved drug other	15 sections
CitraNatal Bloom	HUMAN PRESCRIPTION DRUG LABEL	6	0178-0813	TABLET, FILM COATED	13.20 mg	ORAL	unapproved drug other	15 sections
CitraNatal Bloom	HUMAN PRESCRIPTION DRUG LABEL	6	0178-0813	TABLET, FILM COATED	13.20 mg	ORAL	unapproved drug other	15 sections
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2792	INJECTION	12.50 mg	INTRAVENOUS	NDA	25 sections
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2792	INJECTION	12.50 mg	INTRAVENOUS	NDA	25 sections
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2794	INJECTION	12.50 mg	INTRAVENOUS	NDA	26 sections
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2794	INJECTION	12.50 mg	INTRAVENOUS	NDA	26 sections

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