All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

ferrous gluconate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4491	299-29-6

Description:

Molecule	Description
Synonyms: sodium ferric gluconate complex ferrous gluconate iron gluconate ferroglyconicum glucoferron	iron important in this cpd; RN given refers to ferrous cpd Molecular weight: 446.14 Formula: C12H22FeO14 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 265.04 ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
0.20	g	O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

Date	Agency	Company	Orphan
Feb. 18, 1999	FDA	SANOFI AVENTIS US

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Reversible airways obstruction	240.68	12.73	63	23378	1920	90603086
Vital capacity decreased	236.31	12.73	61	23380	1758	90603248
Sputum culture positive	223.37	12.73	61	23380	2192	90602814
Bronchial secretion retention	194.87	12.73	61	23380	3554	90601452
Presbyacusis	158.43	12.73	50	23391	2992	90602014
Pleural fibrosis	150.21	12.73	50	23391	3546	90601460
Eosinophil count increased	133.54	12.73	66	23375	13015	90591991
Pleural thickening	131.05	12.73	44	23397	3204	90601802
Deafness neurosensory	122.24	12.73	51	23390	6790	90598216
Blood magnesium increased	121.20	12.73	42	23399	3366	90601640
Multiple allergies	118.77	12.73	64	23377	15082	90589924
Upper-airway cough syndrome	116.03	12.73	63	23378	15072	90589934
Oesophageal spasm	114.06	12.73	40	23401	3321	90601685
Epigastric discomfort	110.79	12.73	49	23392	7519	90597487
Smear cervix abnormal	105.12	12.73	37	23404	3105	90601901
Oesophageal pain	103.78	12.73	40	23401	4334	90600672
Cyst	102.72	12.73	60	23381	16501	90588505
Obstructive airways disorder	101.12	12.73	70	23371	25799	90579207
Bone cyst	99.06	12.73	33	23408	2345	90602661
Allergic sinusitis	94.75	12.73	31	23410	2082	90602924
Pulmonary mass	85.56	12.73	66	23375	28706	90576300
Osteosclerosis	79.86	12.73	33	23408	4287	90600719
Hyperhidrosis	79.05	12.73	133	23308	136172	90468834
Abdominal pain	76.98	12.73	251	23190	395470	90209536
Hypotension	75.95	12.73	220	23221	325177	90279829
Blood pressure decreased	73.96	12.73	94	23347	74801	90530205
CFTR gene mutation	72.31	12.73	16	23425	233	90604773
Urticaria	71.59	12.73	210	23231	312524	90292482
Full blood count abnormal	69.77	12.73	65	23376	36532	90568474
Osteopenia	68.91	12.73	53	23388	22949	90582057
Lymphoedema	65.27	12.73	42	23399	13711	90591295
Flushing	63.21	12.73	95	23346	88396	90516610
Dyspnoea	56.48	12.73	405	23036	880550	89724456
Skin lesion	55.65	12.73	58	23383	37307	90567699
Discoloured vomit	55.52	12.73	18	23423	1174	90603832
Blood iron decreased	55.15	12.73	42	23399	17917	90587089
Deformity	54.90	12.73	36	23405	12134	90592872
Blood potassium increased	53.97	12.73	44	23397	20705	90584301
Sputum culture	52.27	12.73	13	23428	321	90604685
Respiratory tract infection	50.36	12.73	69	23372	59009	90545997
Anaphylactic reaction	50.18	12.73	85	23356	87439	90517567
Lip pruritus	49.28	12.73	17	23424	1343	90603663
Heart rate decreased	46.38	12.73	63	23378	53442	90551564
Pancreatitis relapsing	45.25	12.73	16	23425	1360	90603646
Chest discomfort	44.99	12.73	106	23335	138259	90466747
Myocardial infarction	44.50	12.73	90	23351	105882	90499124
Infusion related reaction	43.58	12.73	218	23223	416562	90188444
Toothache	43.36	12.73	40	23401	22190	90582816
Endodontic procedure	42.96	12.73	20	23421	3455	90601551
Occult blood	42.19	12.73	15	23426	1296	90603710
Skin fissures	41.68	12.73	38	23403	20771	90584235
Osteoarthritis	39.64	12.73	126	23315	195604	90409402
Localised infection	39.42	12.73	46	23395	33516	90571490
Tooth disorder	37.16	12.73	43	23398	31047	90573959
Internal haemorrhage	37.16	12.73	22	23419	6198	90598808
Type 2 diabetes mellitus	35.85	12.73	5	23436	203239	90401767
Systemic lupus erythematosus	35.70	12.73	25	23416	361871	90243135
Alopecia	35.10	12.73	46	23395	495025	90109981
Sleep apnoea syndrome	34.79	12.73	42	23399	31705	90573301
Dry eye	34.18	12.73	57	23384	57874	90547132
Glossodynia	33.39	12.73	21	23420	321758	90283248
Blood pressure fluctuation	32.85	12.73	53	23388	52360	90552646
Renal impairment	32.36	12.73	79	23362	105342	90499664
Vomiting	31.21	12.73	326	23115	787967	89817039
Blood uric acid increased	30.46	12.73	21	23420	7683	90597323
Pemphigus	30.40	12.73	24	23417	326840	90278166
Nausea	29.98	12.73	427	23014	1109889	89495117
Synovial disorder	29.66	12.73	15	23426	3103	90601903
Tinnitus	28.97	12.73	45	23396	43057	90561949
Sinusitis	28.52	12.73	28	23413	343060	90261946
Mite allergy	28.51	12.73	10	23431	830	90604176
Burning sensation	27.96	12.73	55	23386	63397	90541609
Therapeutic product effect incomplete	27.50	12.73	8	23433	193888	90411118
Completed suicide	26.97	12.73	3	23438	145055	90459951
Contusion	26.61	12.73	16	23425	251200	90353806
Syncope	26.47	12.73	85	23356	132578	90472428
Product use in unapproved indication	26.19	12.73	29	23412	336207	90268799
Wound	26.03	12.73	24	23417	302956	90302050
Hand deformity	26.03	12.73	23	23418	296339	90308667
Cough	25.48	12.73	173	23268	368789	90236217
Blood creatinine increased	24.99	12.73	70	23371	101316	90503690
Maternal exposure during pregnancy	24.95	12.73	34	23407	360029	90244977
Cystitis	24.89	12.73	54	23387	66664	90538342
Pallor	24.84	12.73	37	23404	34128	90570878
Agitation	24.68	12.73	54	23387	67044	90537962
Vitamin B12 decreased	24.66	12.73	16	23425	5294	90599712
Rheumatic fever	24.28	12.73	5	23436	153116	90451890
Paraesthesia	24.07	12.73	128	23313	250198	90354808
Skin discolouration	24.02	12.73	42	23399	44273	90560733
Post-traumatic stress disorder	23.27	12.73	17	23424	6811	90598195
Respiratory sinus arrhythmia magnitude	22.91	12.73	5	23436	68	90604938
Prostatic specific antigen abnormal	22.91	12.73	5	23436	68	90604938
Anal incontinence	22.05	12.73	24	23417	16206	90588800
Fluid retention	21.89	12.73	61	23380	88030	90516976
Skin depigmentation	21.81	12.73	9	23432	1164	90603842
Oedema peripheral	21.56	12.73	127	23314	257788	90347218
Bone hypertrophy	21.39	12.73	7	23434	470	90604536
Pericarditis	21.36	12.73	23	23418	270128	90334878
Abdominal pain upper	21.20	12.73	153	23288	332521	90272485
Loss of consciousness	21.20	12.73	82	23359	140156	90464850
Off label use	21.19	12.73	183	23258	1102069	89502937
Choluria	21.04	12.73	6	23435	253	90604753
Respiratory alkalosis	20.09	12.73	12	23429	3436	90601570
Contraindicated product administered	19.50	12.73	33	23408	320106	90284900
Hyperphosphataemia	19.27	12.73	12	23429	3699	90601307
Headache	18.98	12.73	138	23303	862608	89742398
Sleep disorder due to general medical condition, insomnia type	18.83	12.73	5	23436	128689	90476317
Anti-cyclic citrullinated peptide antibody positive	17.74	12.73	21	23420	236412	90368594
Dermatitis psoriasiform	17.41	12.73	10	23431	2662	90602344
Sleep disorder therapy	17.32	12.73	6	23435	480	90604526
Anaphylactoid reaction	17.24	12.73	12	23429	4456	90600550
Therapeutic reaction time decreased	16.93	12.73	11	23430	3647	90601359
Febrile neutropenia	16.88	12.73	10	23431	158339	90446667
Hypophosphataemia	16.84	12.73	20	23421	14834	90590172
Rheumatoid arthritis	15.74	12.73	153	23288	362461	90242545
Feeling abnormal	15.71	12.73	85	23356	167150	90437856
Hallucination, auditory	15.68	12.73	20	23421	15955	90589051
Pharyngeal haemorrhage	15.56	12.73	6	23435	650	90604356
Insomnia	15.56	12.73	40	23401	333434	90271572
Liver disorder	15.46	12.73	6	23435	121263	90483743
Analgesic therapy	15.42	12.73	6	23435	666	90604340
Peripheral swelling	15.42	12.73	169	23272	412937	90192069
Memory impairment	15.36	12.73	17	23424	197227	90407779
Cushingoid	15.23	12.73	16	23425	10379	90594627
Epidermolysis	15.11	12.73	6	23435	703	90604303
Product use issue	15.07	12.73	40	23401	329879	90275127
Synovitis	15.05	12.73	40	23401	329712	90275294
Swollen joint count increased	15.03	12.73	5	23436	111201	90493805
Intentional overdose	15.01	12.73	3	23438	93831	90511175
Antinuclear antibody positive	14.94	12.73	15	23426	9226	90595780
Iron deficiency anaemia	14.92	12.73	24	23417	23638	90581368
Rapid eye movements sleep abnormal	14.91	12.73	4	23437	134	90604872
Blood pressure systolic decreased	14.90	12.73	15	23426	9255	90595751
Helicobacter duodenal ulcer	14.88	12.73	3	23438	27	90604979
Stevens-Johnson syndrome	14.84	12.73	27	23414	29349	90575657
Neutropenia	14.81	12.73	22	23419	224882	90380124
Hallucination	14.76	12.73	44	23397	65915	90539091
Antacid therapy	14.75	12.73	6	23435	748	90604258
Appendicolith	14.70	12.73	6	23435	755	90604251
Drug therapy	14.35	12.73	6	23435	803	90604203
Anticoagulant therapy	14.29	12.73	6	23435	811	90604195
Haemoglobin abnormal	14.28	12.73	13	23428	7087	90597919
Road traffic accident	14.26	12.73	5	23436	107621	90497385
Duodenal ulcer perforation	14.23	12.73	22	23419	221266	90383740
Medication error	14.04	12.73	51	23390	84601	90520405
Pain in extremity	13.60	12.73	177	23264	450352	90154654
Nephrogenic systemic fibrosis	13.48	12.73	10	23431	4098	90600908
Colon cancer stage II	12.95	12.73	4	23437	223	90604783
Malaise	12.90	12.73	218	23223	585768	90019238
Dizziness	12.89	12.73	219	23222	589065	90015941
Cold sweat	12.84	12.73	17	23424	14064	90590942

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	546.66	22.33	193	13437	13263	42594442
Appendicitis	480.21	22.33	197	13433	20416	42587289
Cardiogenic shock	362.83	22.33	192	13438	35448	42572257
Stress	339.98	22.33	198	13432	44014	42563691
Ventricular fibrillation	317.10	22.33	166	13464	29957	42577748
Ascites	316.57	22.33	207	13423	56471	42551234
Abdominal distension	297.19	22.33	218	13412	71517	42536188
Blood phosphorus increased	295.90	22.33	121	13509	12404	42595301
Myasthenia gravis	216.89	22.33	105	13525	16032	42591673
Multiple organ dysfunction syndrome	216.10	22.33	206	13424	96829	42510876
Hyponatraemia	204.59	22.33	204	13426	101258	42506447
Hyperphosphataemia	194.23	22.33	91	13539	12913	42594792
Blood uric acid increased	190.53	22.33	95	13535	15452	42592253
Blood cholesterol increased	169.74	22.33	106	13524	26635	42581070
General physical health deterioration	168.86	22.33	224	13406	151022	42456683
Dry mouth	157.70	22.33	118	13512	39761	42567944
Hypophosphataemia	153.38	22.33	91	13539	20854	42586851
Incorrect route of product administration	150.86	22.33	95	13535	24210	42583495
Analgesic therapy	150.51	22.33	62	13568	6462	42601243
Bacterial infection	148.54	22.33	99	13531	27780	42579925
Sleep disorder therapy	147.20	22.33	62	13568	6832	42600873
Neuralgia	143.73	22.33	94	13536	25553	42582152
Abdominal pain	141.61	22.33	233	13397	190238	42417467
Constipation	137.77	22.33	211	13419	162080	42445625
Sepsis	129.90	22.33	230	13400	199104	42408601
Drug therapy	128.33	22.33	55	13575	6325	42601380
Drug intolerance	118.34	22.33	137	13493	80287	42527418
Drug hypersensitivity	101.29	22.33	141	13489	99248	42508457
Chronic obstructive pulmonary disease	83.68	22.33	102	13528	63012	42544693
Thrombosis	83.28	22.33	106	13524	68405	42539300
Swelling	83.20	22.33	95	13535	54790	42552915
Diabetes mellitus	82.75	22.33	99	13531	59988	42547717
Intentional product misuse	82.01	22.33	100	13530	61800	42545905
Sleep disorder	81.07	22.33	88	13542	48007	42559698
Aortic stenosis	80.11	22.33	44	13586	8701	42599004
Vomiting	78.07	22.33	236	13394	289487	42318218
Vitamin D deficiency	77.79	22.33	42	13588	8031	42599674
Antacid therapy	73.47	22.33	34	13596	4683	42603022
End stage renal disease	69.89	22.33	51	13579	16507	42591198
Activated partial thromboplastin time prolonged	69.44	22.33	50	13580	15853	42591852
Anticoagulant therapy	65.41	22.33	31	13599	4504	42603201
C-reactive protein decreased	64.59	22.33	25	13605	2211	42605494
Bacteroides infection	64.49	22.33	26	13604	2561	42605144
Ulcer	54.79	22.33	44	13586	16397	42591308
Somnolence	54.01	22.33	131	13499	140974	42466731
Nausea	49.07	22.33	253	13377	396546	42211159
Total lung capacity decreased	47.23	22.33	23	13607	3547	42604158
Toxicity to various agents	45.56	22.33	9	13621	229127	42378578
Troponin increased	45.21	22.33	42	13588	19020	42588685
Blood calcium increased	44.93	22.33	30	13600	8424	42599281
Hyperlipidaemia	44.57	22.33	44	13586	21472	42586233
Gout	43.22	22.33	49	13581	28006	42579699
Condition aggravated	43.02	22.33	181	13449	260573	42347132
Drug interaction	39.53	22.33	18	13612	266981	42340724
Gastrointestinal disorder	38.50	22.33	60	13570	46593	42561112
Dental caries	37.82	22.33	22	13608	4850	42602855
Pulmonary embolism	37.43	22.33	103	13527	119509	42488196
Bronchopulmonary aspergillosis allergic	36.32	22.33	21	13609	4577	42603128
Blood test abnormal	35.66	22.33	31	13599	12875	42594830
Congenital hiatus hernia	33.03	22.33	22	13608	6152	42601553
Lung opacity	31.71	22.33	21	13609	5816	42601889
Musculoskeletal stiffness	30.41	22.33	61	13569	57704	42550001
Blood pressure fluctuation	30.10	22.33	40	13590	26868	42580837
Haematochezia	27.58	22.33	59	13571	58377	42549328
Neutropenia	27.15	22.33	15	13615	199416	42408289
Anaemia	26.15	22.33	166	13464	280112	42327593
Aspiration	25.46	22.33	30	13600	17856	42589849
Colitis	24.29	22.33	49	13581	46523	42561182
Pyrexia	23.18	22.33	58	13572	393984	42213721

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	559.42	14.19	199	34834	14056	110540210
Appendicitis	441.84	14.19	204	34829	28260	110526006
Cardiogenic shock	296.01	14.19	199	34834	57139	110497127
Blood phosphorus increased	291.22	14.19	129	34904	16211	110538055
Ventricular fibrillation	287.08	14.19	173	34860	41140	110513126
Ascites	256.74	14.19	222	34811	92586	110461680
Stress	226.88	14.19	219	34814	105129	110449137
Blood uric acid increased	219.70	14.19	116	34917	21413	110532853
Myasthenia gravis	214.14	14.19	114	34919	21397	110532869
Vital capacity decreased	211.60	14.19	60	34973	2013	110552253
Reversible airways obstruction	209.21	14.19	62	34971	2437	110551829
Hyperphosphataemia	201.18	14.19	100	34933	16281	110537985
Abdominal pain	189.81	14.19	467	34566	512522	110041744
Abdominal distension	188.49	14.19	254	34779	174849	110379417
Sputum culture positive	174.43	14.19	60	34973	3829	110550437
Analgesic therapy	167.83	14.19	69	34964	7215	110547051
Sleep disorder therapy	166.14	14.19	69	34964	7402	110546864
Multiple organ dysfunction syndrome	164.67	14.19	221	34812	151489	110402777
Bronchial secretion retention	159.42	14.19	60	34973	4964	110549302
Hypophosphataemia	149.60	14.19	106	34927	33076	110521190
Drug therapy	144.34	14.19	62	34971	7229	110547037
Presbyacusis	136.25	14.19	46	34987	2773	110551493
Neuralgia	124.04	14.19	111	34922	48367	110505899
Bacterial infection	118.96	14.19	106	34927	45930	110508336
Pleural fibrosis	117.21	14.19	46	34987	4262	110550004
Oesophageal spasm	113.49	14.19	43	34990	3623	110550643
Hyponatraemia	112.80	14.19	227	34806	217426	110336840
Multiple allergies	110.91	14.19	61	34972	12202	110542064
Sepsis	107.31	14.19	285	34748	327061	110227205
Pleural thickening	105.70	14.19	40	34993	3359	110550907
Upper-airway cough syndrome	103.94	14.19	64	34969	15793	110538473
Smear cervix abnormal	103.10	14.19	37	34996	2675	110551591
Oesophageal pain	99.54	14.19	43	34990	5082	110549184
Blood magnesium increased	94.18	14.19	38	34995	3785	110550481
Incorrect route of product administration	91.29	14.19	107	34926	63954	110490312
Allergic sinusitis	89.78	14.19	30	35003	1751	110552515
Eosinophil count increased	89.70	14.19	65	34968	20993	110533273
Vomiting	87.94	14.19	540	34493	910135	109644131
Antacid therapy	87.22	14.19	40	34993	5444	110548822
Deafness neurosensory	84.66	14.19	47	34986	9572	110544694
Cyst	84.46	14.19	57	34976	16439	110537827
Aortic stenosis	83.80	14.19	52	34981	13007	110541259
Chronic obstructive pulmonary disease	83.60	14.19	135	34898	109023	110445243
Epigastric discomfort	81.96	14.19	45	34988	8970	110545296
End stage renal disease	79.66	14.19	61	34972	21412	110532854
Obstructive airways disorder	79.32	14.19	85	34948	46064	110508202
Bone cyst	79.18	14.19	33	35000	3570	110550696
Anticoagulant therapy	78.72	14.19	37	34996	5324	110548942
Osteosclerosis	75.17	14.19	34	34999	4481	110549785
Full blood count abnormal	73.91	14.19	90	34943	55962	110498304
Pulmonary mass	69.99	14.19	72	34961	37229	110517037
Diabetes mellitus	69.50	14.19	118	34915	99263	110455003
CFTR gene mutation	69.08	14.19	16	35017	233	110554033
Activated partial thromboplastin time prolonged	64.83	14.19	55	34978	22313	110531953
Nausea	64.01	14.19	634	34399	1235056	109319210
Lymphoedema	63.40	14.19	46	34987	14883	110539383
Bacteroides infection	61.68	14.19	26	35007	2893	110551373
Constipation	59.79	14.19	248	34785	357538	110196728
Osteopenia	59.08	14.19	52	34981	22157	110532109
Thrombosis	58.23	14.19	115	34918	108547	110445719
Completed suicide	58.20	14.19	5	35028	242376	110311890
Dry mouth	57.43	14.19	166	34867	199782	110354484
Blood pressure fluctuation	55.19	14.19	91	34942	74733	110479533
Toxicity to various agents	55.04	14.19	43	34990	480512	110073754
Deformity	51.76	14.19	35	34998	10125	110544141
General physical health deterioration	50.61	14.19	267	34766	425028	110129238
C-reactive protein decreased	48.73	14.19	22	35011	2887	110551379
Total lung capacity decreased	47.35	14.19	29	35004	7085	110547181
Gout	47.04	14.19	58	34975	36508	110517758
Sleep disorder	46.87	14.19	154	34879	198490	110355776
Lip pruritus	46.38	14.19	17	35016	1305	110552961
Sputum culture	45.62	14.19	12	35021	302	110553964
Dyspnoea	45.21	14.19	542	34491	1106330	109447936
Urticaria	44.88	14.19	210	34823	318647	110235619
Vitamin D deficiency	44.54	14.19	41	34992	18511	110535755
Troponin increased	42.86	14.19	50	34983	29716	110524550
Discoloured vomit	42.73	14.19	18	35015	1999	110552267
Flushing	42.47	14.19	99	34934	104637	110449629
Hyperhidrosis	42.23	14.19	143	34890	187155	110367111
Infusion related reaction	41.75	14.19	234	34799	380928	110173338
Intentional product misuse	41.73	14.19	114	34919	132790	110421476
Blood iron decreased	41.41	14.19	40	34993	19174	110535092
Endodontic procedure	41.05	14.19	20	35013	3116	110551150
Neutropenia	41.04	14.19	35	34998	374585	110179681
Pancreatitis relapsing	40.42	14.19	16	35017	1516	110552750
Blood cholesterol increased	39.84	14.19	139	34894	184646	110369620
Febrile neutropenia	37.98	14.19	27	35006	316740	110237526
Dry eye	37.35	14.19	65	34968	55728	110498538
Hyperlipidaemia	36.98	14.19	51	34982	35797	110518469
Toothache	36.30	14.19	41	34992	23534	110530732
Heart rate decreased	35.51	14.19	80	34953	82676	110471590
Congenital hiatus hernia	35.36	14.19	23	35010	6236	110548030
Anaphylactic reaction	34.85	14.19	97	34936	114203	110440063
Type 2 diabetes mellitus	34.61	14.19	7	35026	177225	110377041
Localised infection	33.98	14.19	54	34979	42994	110511272
Tooth disorder	33.52	14.19	44	34989	29465	110524801
Respiratory tract infection	32.72	14.19	71	34962	71546	110482720
Drug abuse	32.64	14.19	8	35025	177403	110376863
Ulcer	32.55	14.19	53	34980	43063	110511203
Blood calcium increased	32.36	14.19	34	34999	18006	110536260
Skin fissures	31.79	14.19	39	34994	24419	110529847
Internal haemorrhage	31.75	14.19	26	35007	10045	110544221
Drug intolerance	31.74	14.19	229	34804	406283	110147983
Lung opacity	30.43	14.19	27	35006	11625	110542641
Pyrexia	30.39	14.19	164	34869	898101	109656165
Sinusitis	29.79	14.19	30	35003	296658	110257608
Sleep apnoea syndrome	29.56	14.19	49	34984	40398	110513868
Skin lesion	29.30	14.19	56	34977	51575	110502691
Bronchopulmonary aspergillosis allergic	29.21	14.19	23	35010	8403	110545863
Blood pressure decreased	28.74	14.19	91	34942	115000	110439266
Intentional overdose	28.59	14.19	4	35029	132497	110421769
Osteoarthritis	28.45	14.19	124	34909	182499	110371767
Therapeutic product effect incomplete	28.26	14.19	18	35015	223787	110330479
Drug interaction	27.45	14.19	75	34958	500108	110054158
Blood potassium increased	26.64	14.19	42	34991	33207	110521059
Somnolence	25.82	14.19	172	34861	297277	110256989
Peripheral swelling	25.67	14.19	217	34816	403817	110150449
Blood test abnormal	25.60	14.19	38	34995	28516	110525750
Insomnia	25.56	14.19	47	34986	360543	110193723
Rheumatoid arthritis	24.66	14.19	171	34862	299442	110254824
Synovial disorder	24.58	14.19	14	35019	2993	110551273
Alopecia	24.58	14.19	49	34984	364704	110189562
White blood cell count decreased	24.42	14.19	22	35011	229368	110324898
Headache	24.17	14.19	172	34861	882205	109672061
Cystitis	24.16	14.19	60	34973	65976	110488290
Skin discolouration	23.99	14.19	50	34983	48996	110505270
Sputum discoloured	23.36	14.19	36	34997	27909	110526357
Blood creatinine increased	23.22	14.19	117	34916	182772	110371494
Systemic lupus erythematosus	23.02	14.19	28	35005	254310	110299956
Contusion	22.96	14.19	24	35009	233337	110320929
Dental caries	22.78	14.19	24	35009	12749	110541517
Thrombocytopenia	22.55	14.19	48	34985	348837	110205429
Interstitial lung disease	22.49	14.19	8	35025	139326	110414940
Maternal exposure during pregnancy	22.09	14.19	29	35004	254854	110299412
Respiratory sinus arrhythmia magnitude	21.91	14.19	5	35028	68	110554198
Vitamin B12 decreased	21.87	14.19	16	35017	5241	110549025
Rheumatic fever	21.64	14.19	6	35027	122573	110431693
Pancytopenia	21.26	14.19	21	35012	209592	110344674
Fluid retention	21.24	14.19	72	34961	94235	110460031
Disease progression	20.91	14.19	28	35005	244006	110310260
Post-traumatic stress disorder	20.73	14.19	17	35016	6579	110547687
Glossodynia	20.56	14.19	24	35009	221980	110332286
Chest discomfort	20.53	14.19	109	34924	173739	110380527
Coma	20.38	14.19	6	35027	117863	110436403
Wound	19.98	14.19	27	35006	234410	110319856
Musculoskeletal stiffness	19.76	14.19	154	34879	279668	110274598
Aspiration	19.69	14.19	35	34998	30498	110523768
Memory impairment	19.66	14.19	20	35013	196924	110357342
Lactic acidosis	19.56	14.19	3	35030	92808	110461458
Product use issue	19.22	14.19	44	34989	311651	110242615
Sleep disorder due to general medical condition, insomnia type	18.97	14.19	5	35028	105638	110448628
Hypotension	18.91	14.19	251	34782	523598	110030668
Leukopenia	18.74	14.19	12	35021	148779	110405487
Clostridium test positive	18.60	14.19	20	35013	10873	110543393
Pulmonary embolism	18.59	14.19	124	34909	214350	110339916
Hepatic function abnormal	18.57	14.19	3	35030	89292	110464974
Pericarditis	17.91	14.19	26	35007	219088	110335178
Iron deficiency anaemia	17.62	14.19	34	34999	31525	110522741
Road traffic accident	17.62	14.19	6	35027	107392	110446874
Drug-induced liver injury	17.58	14.19	8	35025	120059	110434207
Epilepsy	17.51	14.19	5	35028	100204	110454062
Therapeutic reaction time decreased	17.42	14.19	14	35019	5265	110549001
Acute kidney injury	17.30	14.19	124	34909	635306	109918960
Oedema peripheral	17.04	14.19	169	34864	328491	110225775
Nephrogenic systemic fibrosis	16.96	14.19	14	35019	5469	110548797
Withdrawal hypertension	16.95	14.19	6	35027	417	110553849
Bone hypertrophy	16.86	14.19	7	35026	750	110553516
Hand deformity	16.83	14.19	27	35006	218479	110335787
Neutrophil count decreased	16.29	14.19	9	35024	120932	110433334
Choluria	16.20	14.19	6	35027	474	110553792
Tinnitus	16.16	14.19	49	34984	60491	110493775
Drug hypersensitivity	16.14	14.19	217	34816	453873	110100393
Pemphigus	16.07	14.19	27	35006	214543	110339723
Breast cancer stage III	15.70	14.19	3	35030	79114	110475152
Swelling	15.61	14.19	175	34858	350866	110203400
Rales	15.50	14.19	28	35005	24711	110529555
Myocardial infarction	15.42	14.19	109	34924	191974	110362292
Cough	15.35	14.19	218	34815	461423	110092843
Synovitis	15.09	14.19	41	34992	274051	110280215
Respiratory symptom	15.02	14.19	21	35012	14924	110539342
Hepatitis	14.83	14.19	5	35028	90049	110464217
COVID-19	14.78	14.19	35	34998	245025	110309241

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	B03AA03	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron bivalent, oral preparations
ATC	B03AD05	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron in combination with folic acid
FDA CS	M0011718	Iron
MeSH PA	D006397	Hematinics
MeSH PA	D006401	Hematologic Agents
FDA EPC	N0000177913	Parenteral Iron Replacement
CHEBI has role	CHEBI:75835	anti-anaemic agent

Related Drugs by ATC class:

B03AA Iron bivalent, oral preparations 8 drugs

ferrous ascorbateferrous aspartateferrous carbonateferrous chlorideferrous fumarateferrous succinateferrous sulfateferrous tartrate

B03AD Iron in combination with folic acid 3 drugs

ferrous fumarateferrous sulfatefolic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Anemia of prematurity	indication	47100003	DOID:11243
Iron deficiency anemia	indication	87522002
Peptic ulcer	contraindication	13200003	DOID:750
Gastroenteritis	contraindication	25374005	DOID:2326
Hemosiderosis	contraindication	39011001	DOID:12119
Hemolytic anemia	contraindication	61261009	DOID:583
Ulcerative colitis	contraindication	64766004	DOID:8577
Diverticular disease	contraindication	397881000
Hemochromatosis	contraindication	399187006	DOID:2352
Repeated Blood Transfusions	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D02394	KEGG_DRUG
4024159	VUID
N0000148626	NUI
6047-12-7	SECONDARY_CAS_RN
34089-81-1	SECONDARY_CAS_RN
4017678	VANDF
4019180	VANDF
4021178	VANDF
4024159	VANDF
CHEBI:31608	CHEBI
CHEMBL3833303	ChEMBL_ID
CHEMBL1201494	ChEMBL_ID
C011819	MESH_SUPPLEMENTAL_RECORD_UI
DB14488	DRUGBANK_ID
U1B11I423Z	UNII
DB09517	DRUGBANK_ID
24942	RXNORM
189358	MMSL
4724	MMSL
5409	MMSL
7975	MMSL
d03822	MMSL
d04387	MMSL
000834	NDDF
007777	NDDF
116130008	SNOMEDCT_US
26736008	SNOMEDCT_US
387147005	SNOMEDCT_US
786421005	SNOMEDCT_US
C0060277	UMLSCUI
23616740	PUBCHEM_CID

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2792	INJECTION	12.50 mg	INTRAVENOUS	NDA	25 sections
Ferrlecit	HUMAN PRESCRIPTION DRUG LABEL	1	0024-2794	INJECTION	12.50 mg	INTRAVENOUS	NDA	26 sections
Sodium Ferric Gluconate Complex in Sucrose	HUMAN PRESCRIPTION DRUG LABEL	1	0143-9298	INJECTION	12.50 mg	INTRAVENOUS	ANDA	24 sections
Sodium Ferric Gluconate Complex in Sucrose	HUMAN PRESCRIPTION DRUG LABEL	1	0143-9570	INJECTION	12.50 mg	INTRAVENOUS	ANDA	24 sections
CitraNatal 90 DHA	HUMAN PRESCRIPTION DRUG LABEL	16	0178-0821	TABLET	5 mg	ORAL	unapproved drug other	11 sections
BioFerr 90	HUMAN PRESCRIPTION DRUG LABEL	6	44523-732	TABLET, FILM COATED	13.20 mg	ORAL	Unapproved drug other	20 sections
Embriva	HUMAN PRESCRIPTION DRUG LABEL	9	85477-322	TABLET	13 mg	ORAL	unapproved drug other	8 sections
Gestyra	HUMAN PRESCRIPTION DRUG LABEL	9	85477-922	TABLET	13 mg	ORAL	unapproved drug other	8 sections