calcium lactate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4383 814-80-2

Description:

MoleculeDescription

Synonyms:

  • calcium lactate
  • Molecular weight: 218.22
  • Formula: C6H10CaO6
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 60.36
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Hypocalcaemia 50.24 21.22 21 1453 31692 63455856
Atypical femur fracture 34.00 21.22 10 1464 5362 63482186
Platelet count decreased 33.54 21.22 25 1449 116097 63371451
Osteonecrosis of jaw 29.57 21.22 15 1459 35108 63452440
Hypercalcaemia 26.50 21.22 13 1461 28309 63459239

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Osteonecrosis of jaw 122.82 42.48 29 289 17860 34938753
Hypocalcaemia 61.93 42.48 18 300 24271 34932342

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Osteonecrosis of jaw 120.28 21.26 42 1640 43184 79699522
Hypocalcaemia 96.13 21.26 37 1645 49887 79692819
Atypical femur fracture 39.86 21.26 11 1671 5178 79737528
Hypercalcaemia 35.62 21.26 17 1665 38413 79704293
Platelet count decreased 33.97 21.26 30 1652 194634 79548072

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA05 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Hyperkalemia indication 14140009
Osteoporosis indication 64859006 DOID:11476
Hypermagnesemia indication 66978005
Postmenopausal osteoporosis indication 102447009
Hypocalcemic tetany indication 190869004
Disorder of electrolytes indication 237840007
Cardiac arrest indication 410429000 DOID:0060319
Neonatal hypocalcemic tetany off-label use 18442000
Poisoning by digitalis glycoside contraindication 12876009
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
End stage renal disease contraindication 46177005 DOID:784
Humoral hypercalcemia of malignancy contraindication 47709007
Heart disease contraindication 56265001 DOID:114
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Ventricular fibrillation contraindication 71908006
Hypercalciuria contraindication 71938000
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00936 KEGG_DRUG
4017706 VUID
N0000146076 NUI
4017684 VANDF
4017706 VANDF
C0108121 UMLSCUI
CHEMBL2106111 ChEMBL_ID
DB13231 DRUGBANK_ID
C110051 MESH_SUPPLEMENTAL_RECORD_UI
13144 PUBCHEM_CID
47622 RXNORM
4339 MMSL
6003 MMSL
d03802 MMSL
000779 NDDF
387217003 SNOMEDCT_US
40339003 SNOMEDCT_US

Pharmaceutical products:

None