calcium lactate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4383 814-80-2

Description:

MoleculeDescription

Synonyms:

  • calcium lactate
  • Molecular weight: 218.22
  • Formula: C6H10CaO6
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 60.36
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Asthma 274.26 35.93 310 20959 241850 90365328
Oedema 225.93 35.93 256 21013 200039 90407139
Lupus vulgaris 189.68 35.93 123 21146 44936 90562242
Lower limb fracture 170.93 35.93 149 21120 84864 90522314
Wheezing 165.02 35.93 239 21030 237841 90369337
Deep vein thrombosis postoperative 146.15 35.93 126 21143 70683 90536495
Nasal oedema 132.44 35.93 52 21217 6532 90600646
Autoimmune disorder 120.17 35.93 117 21152 76627 90530551
Ulcer haemorrhage 116.04 35.93 74 21195 26247 90580931
Porphyria acute 106.25 35.93 61 21208 17914 90589264
Road traffic accident 105.24 35.93 128 21141 107498 90499680
Grip strength 98.05 35.93 46 21223 8919 90598259
Drug hypersensitivity 95.13 35.93 281 20988 463328 90143850
Prescribed overdose 93.64 35.93 115 21154 97510 90509668
Swollen joint count increased 89.38 35.93 120 21149 111086 90496092
Hepatic cirrhosis 88.99 35.93 91 21178 63162 90544016
Sleep disorder due to general medical condition, insomnia type 85.83 35.93 127 21142 128567 90478611
Helicobacter infection 84.46 35.93 173 21096 226677 90380501
Liver disorder 84.24 35.93 122 21147 121147 90486031
Drug tolerance decreased 80.49 35.93 64 21205 32066 90575112
Sciatica 79.34 35.93 108 21161 101274 90505904
Retinitis 76.42 35.93 67 21202 38391 90568787
Eye injury 74.92 35.93 41 21228 10979 90596199
Drug ineffective 69.55 35.93 138 21131 1384160 89223018
Lupus-like syndrome 68.20 35.93 70 21199 48776 90558402
Maternal exposure timing unspecified 67.76 35.93 50 21219 22433 90584745
Muscle injury 67.23 35.93 136 21133 176518 90430660
Fall 64.08 35.93 17 21252 481793 90125385
Duodenal ulcer perforation 63.41 35.93 152 21117 221136 90386042
Hand deformity 61.96 35.93 181 21088 296181 90310997
Liver injury 61.00 35.93 128 21141 170439 90436739
Type 2 diabetes mellitus 60.82 35.93 142 21127 203102 90404076
Respiratory tract infection 60.55 35.93 72 21197 59006 90548172
Bone erosion 60.00 35.93 68 21201 52953 90554225
Irritable bowel syndrome 59.97 35.93 143 21126 207305 90399873
Rheumatic fever 59.59 35.93 119 21150 153002 90454176
Sleep disorder due to a general medical condition 58.66 35.93 62 21207 44676 90562502
X-ray abnormal 57.88 35.93 62 21207 45362 90561816
Death 57.22 35.93 18 21251 456533 90150645
Anti-cyclic citrullinated peptide antibody positive 56.88 35.93 152 21117 236281 90370897
Glossodynia 56.56 35.93 185 21084 321594 90285584
Impaired healing 55.77 35.93 150 21119 234049 90373129
Blood cholesterol increased 55.46 35.93 139 21130 207873 90399305
Hypercholesterolaemia 55.30 35.93 91 21178 100801 90506377
Acute kidney injury 54.13 35.93 6 21263 320381 90286797
Discomfort 53.96 35.93 164 21105 274171 90333007
Laryngitis 53.91 35.93 63 21206 50690 90556488
Urinary tract infection 53.52 35.93 5 21264 305627 90301551
Exostosis 53.21 35.93 64 21205 53070 90554108
Adjustment disorder with depressed mood 53.02 35.93 66 21203 56687 90550491
Folliculitis 52.85 35.93 135 21134 204218 90402960
Chest pain 52.82 35.93 180 21089 319465 90287713
Drug interaction 52.75 35.93 3 21266 276450 90330728
Fibromyalgia 52.04 35.93 135 21134 206134 90401044
Dislocation of vertebra 50.55 35.93 64 21205 55904 90551274
Breast cancer stage III 50.15 35.93 79 21190 84368 90522810
Grip strength decreased 50.06 35.93 83 21186 92493 90514685
Rheumatoid factor positive 49.25 35.93 118 21151 171532 90435646
Back pain 48.70 35.93 8 21261 317167 90290011
Rash pruritic 47.56 35.93 76 21193 82138 90525040
White blood cell count increased 47.18 35.93 68 21201 67173 90540005
Lower respiratory tract infection 46.64 35.93 147 21122 250512 90356666
Psoriatic arthropathy 45.35 35.93 137 21132 228198 90378980
Pulmonary fibrosis 44.78 35.93 86 21183 107417 90499761
Ill-defined disorder 44.58 35.93 119 21150 184772 90422406
Injury 43.59 35.93 123 21146 197226 90409952
Therapeutic response decreased 42.67 35.93 76 21193 89653 90517525
Pancreatitis 42.39 35.93 66 21203 69760 90537418
Swollen joint count 42.34 35.93 26 21243 8627 90598551
Pericarditis 41.89 35.93 149 21120 270002 90337176
Colitis ulcerative 40.90 35.93 60 21209 60206 90546972
Foot deformity 39.92 35.93 59 21210 59592 90547586
Laboratory test abnormal 39.61 35.93 49 21220 41805 90565373
Gastrointestinal disorder 38.45 35.93 140 21129 256547 90350631
Therapy non-responder 38.15 35.93 93 21176 136611 90470567
Somnolence 37.74 35.93 3 21266 209081 90398097
Frequent bowel movements 37.65 35.93 56 21213 56879 90550299
Respiratory disorder 37.60 35.93 60 21209 64756 90542422
Ear infection 36.97 35.93 62 21207 69713 90537465

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Osteonecrosis of jaw 96.61 44.30 29 850 19020 42601436
Mycotic allergy 45.53 44.30 12 867 4879 42615577
Mite allergy 45.16 44.30 12 867 5034 42615422
Spirometry abnormal 44.92 44.30 12 867 5134 42615322
Dust allergy 44.50 44.30 12 867 5320 42615136

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Asthma 312.89 35.40 304 20402 249987 110318606
Oedema 262.21 35.40 255 20451 209721 110358872
Wheezing 214.12 35.40 251 20455 254979 110313614
Lupus vulgaris 210.43 35.40 110 20596 33773 110534820
Lower limb fracture 173.14 35.40 130 20576 75218 110493375
Nasal oedema 149.40 35.40 54 20652 6785 110561808
Deep vein thrombosis postoperative 142.24 35.40 105 20601 59186 110509407
Drug hypersensitivity 126.68 35.40 269 20437 453821 110114772
Porphyria acute 122.40 35.40 63 20643 18717 110549876
Swollen joint count increased 118.33 35.40 109 20597 83552 110485041
Autoimmune disorder 111.94 35.40 95 20611 65388 110503205
Grip strength 110.46 35.40 47 20659 9094 110559499
Helicobacter infection 105.30 35.40 149 20557 181728 110386865
Drug tolerance decreased 104.96 35.40 65 20641 27475 110541118
Ulcer haemorrhage 103.49 35.40 60 20646 22511 110546082
Retinitis 102.64 35.40 68 20638 32259 110536334
Sciatica 101.83 35.40 105 20601 92294 110476299
Hepatic cirrhosis 101.29 35.40 91 20615 67535 110501058
Road traffic accident 93.84 35.40 108 20598 107290 110461303
Glossodynia 93.54 35.40 157 20549 221847 110346746
Lupus-like syndrome 92.81 35.40 70 20636 40722 110527871
Sleep disorder due to general medical condition, insomnia type 91.91 35.40 106 20600 105537 110463056
Hand deformity 90.03 35.40 153 20553 218353 110350240
Sleep disorder due to a general medical condition 89.87 35.40 76 20630 52036 110516557
Acute kidney injury 87.03 35.40 9 20697 635421 109933172
Prescribed overdose 86.68 35.40 94 20612 87487 110481106
Anti-cyclic citrullinated peptide antibody positive 86.57 35.40 136 20570 181848 110386745
Maternal exposure timing unspecified 86.23 35.40 52 20654 20961 110547632
X-ray abnormal 85.81 35.40 65 20641 38052 110530541
Rheumatoid factor positive 85.44 35.40 114 20592 131526 110437067
Hypotension 84.84 35.40 3 20703 523846 110044747
Adjustment disorder with depressed mood 84.01 35.40 68 20638 43815 110524778
Bone erosion 82.80 35.40 69 20637 46302 110522291
Hypercholesterolaemia 82.15 35.40 93 20613 90744 110477849
Muscle injury 80.94 35.40 115 20591 140692 110427901
Rheumatic fever 80.85 35.40 107 20599 122472 110446121
Drug interaction 80.53 35.40 3 20703 500180 110068413
Dislocation of vertebra 80.02 35.40 66 20640 43655 110524938
Grip strength decreased 77.51 35.40 85 20621 80089 110488504
Duodenal ulcer perforation 76.60 35.40 127 20579 177573 110391020
Irritable bowel syndrome 75.72 35.40 121 20585 164094 110404499
Laryngitis 75.50 35.40 63 20643 42348 110526245
Breast cancer stage III 73.24 35.40 82 20624 79035 110489558
Exostosis 73.10 35.40 64 20642 45892 110522701
Ill-defined disorder 72.90 35.40 116 20590 156737 110411856
Liver injury 72.34 35.40 113 20593 150300 110418293
Liver disorder 71.40 35.40 109 20597 142134 110426459
Pulmonary fibrosis 70.27 35.40 91 20615 101951 110466642
Drug ineffective 69.88 35.40 111 20595 1520429 109048164
Discomfort 68.96 35.40 135 20571 214572 110354021
Impaired healing 68.48 35.40 128 20578 196589 110372004
Death 66.42 35.40 24 20682 698845 109869748
Type 2 diabetes mellitus 66.33 35.40 119 20587 177113 110391480
Respiratory tract infection 65.90 35.40 74 20632 71543 110497050
Folliculitis 62.01 35.40 112 20594 167541 110401052
Foot deformity 60.57 35.40 59 20647 48421 110520172
Pemphigus 58.38 35.40 126 20580 214444 110354149
Fibromyalgia 57.97 35.40 110 20596 170799 110397794
Blood cholesterol increased 56.69 35.40 114 20592 184671 110383922
Pericarditis 56.58 35.40 126 20580 218988 110349605
Lower respiratory tract infection 56.39 35.40 134 20572 242972 110325621
Blister 55.66 35.40 128 20578 227248 110341345
Wound 55.22 35.40 130 20576 234307 110334286
Fall 53.58 35.40 23 20683 603459 109965134
Joint dislocation 53.14 35.40 47 20659 34143 110534450
Ear infection 52.95 35.40 62 20644 62670 110505923
Wound infection 52.80 35.40 77 20629 96388 110472205
Injury 51.57 35.40 107 20599 177158 110391435
Facet joint syndrome 51.13 35.40 76 20630 96752 110471841
Mobility decreased 49.89 35.40 126 20580 237296 110331297
Pregnancy 49.10 35.40 54 20652 51013 110517580
Laboratory test abnormal 48.37 35.40 50 20656 44029 110524564
Walking aid user 48.29 35.40 39 20667 25036 110543557
Swollen joint count 47.74 35.40 26 20680 8648 110559945
Hepatic enzyme increased 47.52 35.40 150 20556 320742 110247851
Gastrointestinal disorder 47.33 35.40 125 20581 241827 110326766
Psoriatic arthropathy 45.12 35.40 108 20598 196653 110371940
Respiratory disorder 45.03 35.40 61 20645 71321 110497272
Eye injury 44.79 35.40 24 20682 7731 110560862
Joint range of motion decreased 44.54 35.40 81 20625 121751 110446842
Systemic lupus erythematosus 44.37 35.40 126 20580 254212 110314381
Pancreatitis 43.19 35.40 69 20637 93464 110475129
Prescribed underdose 43.11 35.40 57 20649 65117 110503476
Peripheral venous disease 42.95 35.40 65 20641 84052 110484541
White blood cell count increased 42.75 35.40 70 20636 96772 110471821
Osteoporosis 42.61 35.40 66 20640 87086 110481507
Live birth 41.75 35.40 58 20648 69426 110499167
Colitis ulcerative 41.24 35.40 61 20645 77302 110491291
Somnolence 41.22 35.40 4 20702 297445 110271148
Chest pain 41.04 35.40 159 20547 376216 110192377
Synovitis 39.54 35.40 127 20579 273965 110294628
Frequent bowel movements 39.08 35.40 57 20649 71333 110497260
Urinary tract infection 39.00 35.40 7 20699 326275 110242318
Arthropathy 38.59 35.40 130 20576 287392 110281201
Therapy non-responder 37.86 35.40 88 20618 157219 110411374
C-reactive protein abnormal 37.37 35.40 78 20628 129617 110438976
Bursitis 37.28 35.40 78 20628 129840 110438753
Off label use 37.21 35.40 150 20556 1500035 109068558
Sepsis 37.07 35.40 8 20698 327338 110241255
Neutropenia 37.04 35.40 12 20694 374608 110193985
Rash pruritic 36.86 35.40 66 20640 98003 110470590
Maternal exposure during pregnancy 36.67 35.40 118 20588 254765 110313828
Osteonecrosis of jaw 36.50 35.40 45 20661 47972 110520621
Back pain 36.47 35.40 12 20694 370984 110197609
Sleep disorder 36.19 35.40 100 20606 198544 110370049
Amnesia 35.91 35.40 68 20638 105340 110463253
Lip dry 35.89 35.40 66 20640 100017 110468576
Joint stiffness 35.81 35.40 53 20653 67190 110501403

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA05 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium

Related Drugs by ATC class:

A12AA Calcium 11 drugs
calcium carbonatecalcium chloridecalcium citratecalcium glubionatecalcium glucoheptonatecalcium gluconatecalcium glycerylphosphatecalcium lactate gluconatecalcium levulinatecalcium pangamatecalcium phosphate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Hyperkalemia indication 14140009
Osteoporosis indication 64859006 DOID:11476
Hypermagnesemia indication 66978005
Postmenopausal osteoporosis indication 102447009
Hypocalcemic tetany indication 190869004
Disorder of electrolytes indication 237840007
Cardiac arrest indication 410429000 DOID:0060319
Neonatal hypocalcemic tetany off-label use 18442000
Poisoning by digitalis glycoside contraindication 12876009
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
End stage renal disease contraindication 46177005 DOID:784
Humoral hypercalcemia of malignancy contraindication 47709007
Heart disease contraindication 56265001 DOID:114
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Ventricular fibrillation contraindication 71908006
Hypercalciuria contraindication 71938000
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00936 KEGG_DRUG
4017706 VUID
N0000146076 NUI
4017684 VANDF
4017706 VANDF
C0108121 UMLSCUI
CHEMBL2106111 ChEMBL_ID
DB13231 DRUGBANK_ID
C110051 MESH_SUPPLEMENTAL_RECORD_UI
13144 PUBCHEM_CID
47622 RXNORM
4339 MMSL
6003 MMSL
d03802 MMSL
000779 NDDF
387217003 SNOMEDCT_US
40339003 SNOMEDCT_US

Pharmaceutical products:

None