All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

calcium lactate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4383	814-80-2

Description:

Molecule	Description
Synonyms: calcium lactate	Molecular weight: 218.22 Formula: C6H10CaO6 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 60.36 ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
2	g	O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Asthma	274.26	35.93	310	20959	241850	90365328
Oedema	225.93	35.93	256	21013	200039	90407139
Lupus vulgaris	189.68	35.93	123	21146	44936	90562242
Lower limb fracture	170.93	35.93	149	21120	84864	90522314
Wheezing	165.02	35.93	239	21030	237841	90369337
Deep vein thrombosis postoperative	146.15	35.93	126	21143	70683	90536495
Nasal oedema	132.44	35.93	52	21217	6532	90600646
Autoimmune disorder	120.17	35.93	117	21152	76627	90530551
Ulcer haemorrhage	116.04	35.93	74	21195	26247	90580931
Porphyria acute	106.25	35.93	61	21208	17914	90589264
Road traffic accident	105.24	35.93	128	21141	107498	90499680
Grip strength	98.05	35.93	46	21223	8919	90598259
Drug hypersensitivity	95.13	35.93	281	20988	463328	90143850
Prescribed overdose	93.64	35.93	115	21154	97510	90509668
Swollen joint count increased	89.38	35.93	120	21149	111086	90496092
Hepatic cirrhosis	88.99	35.93	91	21178	63162	90544016
Sleep disorder due to general medical condition, insomnia type	85.83	35.93	127	21142	128567	90478611
Helicobacter infection	84.46	35.93	173	21096	226677	90380501
Liver disorder	84.24	35.93	122	21147	121147	90486031
Drug tolerance decreased	80.49	35.93	64	21205	32066	90575112
Sciatica	79.34	35.93	108	21161	101274	90505904
Retinitis	76.42	35.93	67	21202	38391	90568787
Eye injury	74.92	35.93	41	21228	10979	90596199
Drug ineffective	69.55	35.93	138	21131	1384160	89223018
Lupus-like syndrome	68.20	35.93	70	21199	48776	90558402
Maternal exposure timing unspecified	67.76	35.93	50	21219	22433	90584745
Muscle injury	67.23	35.93	136	21133	176518	90430660
Fall	64.08	35.93	17	21252	481793	90125385
Duodenal ulcer perforation	63.41	35.93	152	21117	221136	90386042
Hand deformity	61.96	35.93	181	21088	296181	90310997
Liver injury	61.00	35.93	128	21141	170439	90436739
Type 2 diabetes mellitus	60.82	35.93	142	21127	203102	90404076
Respiratory tract infection	60.55	35.93	72	21197	59006	90548172
Bone erosion	60.00	35.93	68	21201	52953	90554225
Irritable bowel syndrome	59.97	35.93	143	21126	207305	90399873
Rheumatic fever	59.59	35.93	119	21150	153002	90454176
Sleep disorder due to a general medical condition	58.66	35.93	62	21207	44676	90562502
X-ray abnormal	57.88	35.93	62	21207	45362	90561816
Death	57.22	35.93	18	21251	456533	90150645
Anti-cyclic citrullinated peptide antibody positive	56.88	35.93	152	21117	236281	90370897
Glossodynia	56.56	35.93	185	21084	321594	90285584
Impaired healing	55.77	35.93	150	21119	234049	90373129
Blood cholesterol increased	55.46	35.93	139	21130	207873	90399305
Hypercholesterolaemia	55.30	35.93	91	21178	100801	90506377
Acute kidney injury	54.13	35.93	6	21263	320381	90286797
Discomfort	53.96	35.93	164	21105	274171	90333007
Laryngitis	53.91	35.93	63	21206	50690	90556488
Urinary tract infection	53.52	35.93	5	21264	305627	90301551
Exostosis	53.21	35.93	64	21205	53070	90554108
Adjustment disorder with depressed mood	53.02	35.93	66	21203	56687	90550491
Folliculitis	52.85	35.93	135	21134	204218	90402960
Chest pain	52.82	35.93	180	21089	319465	90287713
Drug interaction	52.75	35.93	3	21266	276450	90330728
Fibromyalgia	52.04	35.93	135	21134	206134	90401044
Dislocation of vertebra	50.55	35.93	64	21205	55904	90551274
Breast cancer stage III	50.15	35.93	79	21190	84368	90522810
Grip strength decreased	50.06	35.93	83	21186	92493	90514685
Rheumatoid factor positive	49.25	35.93	118	21151	171532	90435646
Back pain	48.70	35.93	8	21261	317167	90290011
Rash pruritic	47.56	35.93	76	21193	82138	90525040
White blood cell count increased	47.18	35.93	68	21201	67173	90540005
Lower respiratory tract infection	46.64	35.93	147	21122	250512	90356666
Psoriatic arthropathy	45.35	35.93	137	21132	228198	90378980
Pulmonary fibrosis	44.78	35.93	86	21183	107417	90499761
Ill-defined disorder	44.58	35.93	119	21150	184772	90422406
Injury	43.59	35.93	123	21146	197226	90409952
Therapeutic response decreased	42.67	35.93	76	21193	89653	90517525
Pancreatitis	42.39	35.93	66	21203	69760	90537418
Swollen joint count	42.34	35.93	26	21243	8627	90598551
Pericarditis	41.89	35.93	149	21120	270002	90337176
Colitis ulcerative	40.90	35.93	60	21209	60206	90546972
Foot deformity	39.92	35.93	59	21210	59592	90547586
Laboratory test abnormal	39.61	35.93	49	21220	41805	90565373
Gastrointestinal disorder	38.45	35.93	140	21129	256547	90350631
Therapy non-responder	38.15	35.93	93	21176	136611	90470567
Somnolence	37.74	35.93	3	21266	209081	90398097
Frequent bowel movements	37.65	35.93	56	21213	56879	90550299
Respiratory disorder	37.60	35.93	60	21209	64756	90542422
Ear infection	36.97	35.93	62	21207	69713	90537465

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Osteonecrosis of jaw	96.61	44.30	29	850	19020	42601436
Mycotic allergy	45.53	44.30	12	867	4879	42615577
Mite allergy	45.16	44.30	12	867	5034	42615422
Spirometry abnormal	44.92	44.30	12	867	5134	42615322
Dust allergy	44.50	44.30	12	867	5320	42615136

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Asthma	312.89	35.40	304	20402	249987	110318606
Oedema	262.21	35.40	255	20451	209721	110358872
Wheezing	214.12	35.40	251	20455	254979	110313614
Lupus vulgaris	210.43	35.40	110	20596	33773	110534820
Lower limb fracture	173.14	35.40	130	20576	75218	110493375
Nasal oedema	149.40	35.40	54	20652	6785	110561808
Deep vein thrombosis postoperative	142.24	35.40	105	20601	59186	110509407
Drug hypersensitivity	126.68	35.40	269	20437	453821	110114772
Porphyria acute	122.40	35.40	63	20643	18717	110549876
Swollen joint count increased	118.33	35.40	109	20597	83552	110485041
Autoimmune disorder	111.94	35.40	95	20611	65388	110503205
Grip strength	110.46	35.40	47	20659	9094	110559499
Helicobacter infection	105.30	35.40	149	20557	181728	110386865
Drug tolerance decreased	104.96	35.40	65	20641	27475	110541118
Ulcer haemorrhage	103.49	35.40	60	20646	22511	110546082
Retinitis	102.64	35.40	68	20638	32259	110536334
Sciatica	101.83	35.40	105	20601	92294	110476299
Hepatic cirrhosis	101.29	35.40	91	20615	67535	110501058
Road traffic accident	93.84	35.40	108	20598	107290	110461303
Glossodynia	93.54	35.40	157	20549	221847	110346746
Lupus-like syndrome	92.81	35.40	70	20636	40722	110527871
Sleep disorder due to general medical condition, insomnia type	91.91	35.40	106	20600	105537	110463056
Hand deformity	90.03	35.40	153	20553	218353	110350240
Sleep disorder due to a general medical condition	89.87	35.40	76	20630	52036	110516557
Acute kidney injury	87.03	35.40	9	20697	635421	109933172
Prescribed overdose	86.68	35.40	94	20612	87487	110481106
Anti-cyclic citrullinated peptide antibody positive	86.57	35.40	136	20570	181848	110386745
Maternal exposure timing unspecified	86.23	35.40	52	20654	20961	110547632
X-ray abnormal	85.81	35.40	65	20641	38052	110530541
Rheumatoid factor positive	85.44	35.40	114	20592	131526	110437067
Hypotension	84.84	35.40	3	20703	523846	110044747
Adjustment disorder with depressed mood	84.01	35.40	68	20638	43815	110524778
Bone erosion	82.80	35.40	69	20637	46302	110522291
Hypercholesterolaemia	82.15	35.40	93	20613	90744	110477849
Muscle injury	80.94	35.40	115	20591	140692	110427901
Rheumatic fever	80.85	35.40	107	20599	122472	110446121
Drug interaction	80.53	35.40	3	20703	500180	110068413
Dislocation of vertebra	80.02	35.40	66	20640	43655	110524938
Grip strength decreased	77.51	35.40	85	20621	80089	110488504
Duodenal ulcer perforation	76.60	35.40	127	20579	177573	110391020
Irritable bowel syndrome	75.72	35.40	121	20585	164094	110404499
Laryngitis	75.50	35.40	63	20643	42348	110526245
Breast cancer stage III	73.24	35.40	82	20624	79035	110489558
Exostosis	73.10	35.40	64	20642	45892	110522701
Ill-defined disorder	72.90	35.40	116	20590	156737	110411856
Liver injury	72.34	35.40	113	20593	150300	110418293
Liver disorder	71.40	35.40	109	20597	142134	110426459
Pulmonary fibrosis	70.27	35.40	91	20615	101951	110466642
Drug ineffective	69.88	35.40	111	20595	1520429	109048164
Discomfort	68.96	35.40	135	20571	214572	110354021
Impaired healing	68.48	35.40	128	20578	196589	110372004
Death	66.42	35.40	24	20682	698845	109869748
Type 2 diabetes mellitus	66.33	35.40	119	20587	177113	110391480
Respiratory tract infection	65.90	35.40	74	20632	71543	110497050
Folliculitis	62.01	35.40	112	20594	167541	110401052
Foot deformity	60.57	35.40	59	20647	48421	110520172
Pemphigus	58.38	35.40	126	20580	214444	110354149
Fibromyalgia	57.97	35.40	110	20596	170799	110397794
Blood cholesterol increased	56.69	35.40	114	20592	184671	110383922
Pericarditis	56.58	35.40	126	20580	218988	110349605
Lower respiratory tract infection	56.39	35.40	134	20572	242972	110325621
Blister	55.66	35.40	128	20578	227248	110341345
Wound	55.22	35.40	130	20576	234307	110334286
Fall	53.58	35.40	23	20683	603459	109965134
Joint dislocation	53.14	35.40	47	20659	34143	110534450
Ear infection	52.95	35.40	62	20644	62670	110505923
Wound infection	52.80	35.40	77	20629	96388	110472205
Injury	51.57	35.40	107	20599	177158	110391435
Facet joint syndrome	51.13	35.40	76	20630	96752	110471841
Mobility decreased	49.89	35.40	126	20580	237296	110331297
Pregnancy	49.10	35.40	54	20652	51013	110517580
Laboratory test abnormal	48.37	35.40	50	20656	44029	110524564
Walking aid user	48.29	35.40	39	20667	25036	110543557
Swollen joint count	47.74	35.40	26	20680	8648	110559945
Hepatic enzyme increased	47.52	35.40	150	20556	320742	110247851
Gastrointestinal disorder	47.33	35.40	125	20581	241827	110326766
Psoriatic arthropathy	45.12	35.40	108	20598	196653	110371940
Respiratory disorder	45.03	35.40	61	20645	71321	110497272
Eye injury	44.79	35.40	24	20682	7731	110560862
Joint range of motion decreased	44.54	35.40	81	20625	121751	110446842
Systemic lupus erythematosus	44.37	35.40	126	20580	254212	110314381
Pancreatitis	43.19	35.40	69	20637	93464	110475129
Prescribed underdose	43.11	35.40	57	20649	65117	110503476
Peripheral venous disease	42.95	35.40	65	20641	84052	110484541
White blood cell count increased	42.75	35.40	70	20636	96772	110471821
Osteoporosis	42.61	35.40	66	20640	87086	110481507
Live birth	41.75	35.40	58	20648	69426	110499167
Colitis ulcerative	41.24	35.40	61	20645	77302	110491291
Somnolence	41.22	35.40	4	20702	297445	110271148
Chest pain	41.04	35.40	159	20547	376216	110192377
Synovitis	39.54	35.40	127	20579	273965	110294628
Frequent bowel movements	39.08	35.40	57	20649	71333	110497260
Urinary tract infection	39.00	35.40	7	20699	326275	110242318
Arthropathy	38.59	35.40	130	20576	287392	110281201
Therapy non-responder	37.86	35.40	88	20618	157219	110411374
C-reactive protein abnormal	37.37	35.40	78	20628	129617	110438976
Bursitis	37.28	35.40	78	20628	129840	110438753
Off label use	37.21	35.40	150	20556	1500035	109068558
Sepsis	37.07	35.40	8	20698	327338	110241255
Neutropenia	37.04	35.40	12	20694	374608	110193985
Rash pruritic	36.86	35.40	66	20640	98003	110470590
Maternal exposure during pregnancy	36.67	35.40	118	20588	254765	110313828
Osteonecrosis of jaw	36.50	35.40	45	20661	47972	110520621
Back pain	36.47	35.40	12	20694	370984	110197609
Sleep disorder	36.19	35.40	100	20606	198544	110370049
Amnesia	35.91	35.40	68	20638	105340	110463253
Lip dry	35.89	35.40	66	20640	100017	110468576
Joint stiffness	35.81	35.40	53	20653	67190	110501403

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12AA05	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS CALCIUM Calcium

Related Drugs by ATC class:

A12AA Calcium 11 drugs

calcium carbonatecalcium chloridecalcium citratecalcium glubionatecalcium glucoheptonatecalcium gluconatecalcium glycerylphosphatecalcium lactate gluconatecalcium levulinatecalcium pangamatecalcium phosphate

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypocalcemia	indication	5291005
Hyperkalemia	indication	14140009
Osteoporosis	indication	64859006	DOID:11476
Hypermagnesemia	indication	66978005
Postmenopausal osteoporosis	indication	102447009
Hypocalcemic tetany	indication	190869004
Disorder of electrolytes	indication	237840007
Cardiac arrest	indication	410429000	DOID:0060319
Neonatal hypocalcemic tetany	off-label use	18442000
Poisoning by digitalis glycoside	contraindication	12876009
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
End stage renal disease	contraindication	46177005	DOID:784
Humoral hypercalcemia of malignancy	contraindication	47709007
Heart disease	contraindication	56265001	DOID:114
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Ventricular fibrillation	contraindication	71908006
Hypercalciuria	contraindication	71938000
Kidney disease	contraindication	90708001	DOID:557
Kidney stone	contraindication	95570007

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
D00936	KEGG_DRUG
4017706	VUID
N0000146076	NUI
4017684	VANDF
4017706	VANDF
C0108121	UMLSCUI
CHEMBL2106111	ChEMBL_ID
DB13231	DRUGBANK_ID
C110051	MESH_SUPPLEMENTAL_RECORD_UI
13144	PUBCHEM_CID
47622	RXNORM
4339	MMSL
6003	MMSL
d03802	MMSL
000779	NDDF
387217003	SNOMEDCT_US
40339003	SNOMEDCT_US

Pharmaceutical products:

None