All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

calcium glubionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4842	12569-38-9

Description:

Molecule	Description
Synonyms: calcium glubionate Neo-Calglucon calcium glubionate monohydrate	Molecular weight: 610.53 Formula: C18H34CaO20 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 220.43 ALOGS: ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Liver injury	1024.16	198.93	1257	131939	169310	90325941
Psoriatic arthropathy	964.08	198.93	1417	131779	226918	90268333
Type 2 diabetes mellitus	785.93	198.93	1211	131985	202033	90293218
Fibromyalgia	714.74	198.93	1169	132027	205100	90290151
Rheumatic fever	675.78	198.93	971	132225	152150	90343101
Helicobacter infection	667.97	198.93	1196	132000	225654	90269597
Blood cholesterol increased	654.24	198.93	1129	132067	206883	90288368
Hand deformity	652.67	198.93	1382	131814	294980	90200271
Duodenal ulcer perforation	644.25	198.93	1161	132035	220127	90275124
Injury	629.62	198.93	1078	132118	196271	90298980
Glossodynia	609.86	198.93	1413	131783	320366	90174885
Hypercholesterolaemia	607.26	198.93	745	132451	100147	90395104
Joint range of motion decreased	566.21	198.93	838	132358	134805	90360446
Pemphigus	561.80	198.93	1382	131814	325482	90169769
Folliculitis	551.66	198.93	1038	132158	203315	90291936
Facet joint syndrome	549.73	198.93	700	132496	97689	90397562
Wound	545.18	198.93	1304	131892	301676	90193575
Pericarditis	542.37	198.93	1214	131982	268937	90226314
Grip strength decreased	535.24	198.93	670	132526	91906	90403345
Cough	519.71	198.93	4	133192	368958	90126293
Systemic lupus erythematosus	505.35	198.93	1416	131780	360480	90134771
Lip dry	497.03	198.93	675	132521	100280	90394971
Mobility decreased	474.60	198.93	1101	132095	249633	90245618
Swollen joint count increased	472.60	198.93	693	132503	110513	90384738
Wound infection	457.85	198.93	667	132529	105735	90389516
Irritable bowel syndrome	456.87	198.93	968	132228	206480	90288771
Muscle injury	455.27	198.93	880	132316	175774	90319477
Anti-cyclic citrullinated peptide antibody positive	442.81	198.93	1034	132162	235399	90259852
Rheumatoid arthritis	441.17	198.93	1351	131845	361263	90133988
Deep vein thrombosis postoperative	440.77	198.93	532	132664	70277	90424974
Impaired healing	427.45	198.93	1014	132182	233185	90262066
Blister	427.03	198.93	1068	132128	253930	90241321
Adjustment disorder with depressed mood	419.68	198.93	466	132730	56287	90438964
Gait inability	411.34	198.93	757	132439	145699	90349552
Autoimmune disorder	409.76	198.93	534	132662	76210	90419041
Rheumatoid factor positive	409.60	198.93	828	132368	170822	90324429
Arthropathy	402.86	198.93	1318	131878	364924	90130327
Breast cancer stage III	390.62	198.93	548	132648	83899	90411352
Synovitis	371.85	198.93	1197	131999	328555	90166696
Hypotension	368.71	198.93	29	133167	325368	90169883
Back pain	357.33	198.93	29	133167	317146	90178105
Pulmonary fibrosis	356.67	198.93	598	132598	106905	90388346
Sleep disorder	355.37	198.93	852	132344	197178	90298073
Bursitis	347.83	198.93	663	132533	130991	90364260
C-reactive protein abnormal	335.75	198.93	641	132555	126788	90368463
Dislocation of vertebra	334.48	198.93	412	132784	55556	90439695
Wheezing	331.25	198.93	931	132265	237149	90258102
Stomatitis	330.52	198.93	1020	132176	273678	90221573
Peripheral venous disease	326.52	198.93	502	132694	83419	90411832
Hypoaesthesia	323.33	198.93	1106	132090	313104	90182147
General physical health deterioration	316.07	198.93	1192	132004	353923	90141328
Erythema	315.60	198.93	4	133192	229242	90266009
Lower limb fracture	309.17	198.93	493	132703	84520	90410731
Road traffic accident	295.42	198.93	551	132645	107075	90388176
Dyspepsia	293.53	198.93	793	132403	197367	90297884
Fall	288.17	198.93	176	133020	481634	90013617
Discomfort	278.93	198.93	962	132234	273373	90221878
Hepatic enzyme increased	277.56	198.93	1157	132039	359579	90135672
Urticaria	273.42	198.93	1044	132152	311690	90183561
X-ray abnormal	272.40	198.93	335	132861	45089	90450162
Swelling	269.54	198.93	1274	131922	417784	90077467
Sciatica	265.79	198.93	509	132687	100873	90394378
Breast cancer stage II	264.39	198.93	292	132904	35042	90460209
Obesity	261.13	198.93	517	132679	104990	90390261
Drug ineffective	260.14	198.93	1102	132094	1383196	89112055
Sleep disorder due to general medical condition, insomnia type	258.50	198.93	579	132617	128115	90367136
Blood pressure increased	257.09	198.93	7	133189	197210	90298041
Musculoskeletal stiffness	255.97	198.93	986	132210	295546	90199705
Lupus vulgaris	253.72	198.93	322	132874	44737	90450514
Prescribed underdose	249.67	198.93	418	132778	74601	90420650
Death	243.40	198.93	189	133007	456362	90038889
Anti-cyclic citrullinated peptide antibody	242.79	198.93	247	132949	26974	90468277
Bone erosion	239.07	198.93	340	132856	52681	90442570
Myalgia	232.91	198.93	5	133191	175120	90320131
Dry mouth	229.16	198.93	692	132504	183367	90311884
Ill-defined disorder	226.32	198.93	691	132505	184200	90311051
Feeling abnormal	225.53	198.93	4	133192	167231	90328020
Alopecia	225.48	198.93	1369	131827	493702	90001549
Prescribed overdose	224.46	198.93	464	132732	97161	90398090
Haemoglobin decreased	222.11	198.93	3	133193	161953	90333298
Lower respiratory tract infection	221.60	198.93	840	132356	249819	90245432
Blepharospasm	217.49	198.93	333	132863	55112	90440139
Osteoarthritis	213.49	198.93	703	132493	195027	90300224
Nail disorder	209.86	198.93	339	132857	58728	90436523
White blood cell count decreased	207.05	198.93	9	133187	167100	90328151
Infusion related reaction	204.80	198.93	1176	132020	415604	90079647
Night sweats	204.46	198.93	529	132667	128237	90367014
Abdominal discomfort	201.70	198.93	1295	131901	476033	90019218

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Psoriatic arthropathy	858.93	291.08	995	104039	195766	110288499
Type 2 diabetes mellitus	844.49	291.08	938	104096	176294	110307971
Fibromyalgia	835.85	291.08	917	104117	169992	110314273
Helicobacter infection	826.30	291.08	939	104095	180938	110303327
Hand deformity	824.43	291.08	1026	104008	217480	110266785
Liver injury	818.30	291.08	854	104180	149559	110334706
Facet joint syndrome	798.27	291.08	692	104342	96136	110388129
Rheumatic fever	797.45	291.08	767	104267	121812	110362453
Duodenal ulcer perforation	787.89	291.08	906	104128	176794	110307471
Glossodynia	767.30	291.08	998	104036	221006	110263259
Lip dry	725.25	291.08	665	104369	99418	110384847
Pemphigus	720.40	291.08	951	104083	213619	110270646
Systemic lupus erythematosus	714.07	291.08	1034	104000	253304	110230961
Folliculitis	703.43	291.08	831	104203	166822	110317443
Blood cholesterol increased	689.31	291.08	863	104171	183922	110300343
Wound	666.63	291.08	959	104075	233478	110250787
Pericarditis	659.44	291.08	921	104113	218193	110266072
Injury	615.51	291.08	799	104235	176466	110307799
Joint range of motion decreased	604.53	291.08	659	104375	121173	110363092
Anti-cyclic citrullinated peptide antibody positive	595.90	291.08	797	104237	181187	110303078
Muscle injury	590.61	291.08	698	104336	140109	110344156
Irritable bowel syndrome	571.35	291.08	741	104293	163474	110320791
Synovitis	559.41	291.08	963	104071	273129	110211136
Swollen joint count increased	556.18	291.08	530	104504	83131	110401134
Grip strength decreased	550.33	291.08	517	104517	79657	110404608
C-reactive protein abnormal	540.72	291.08	641	104393	129054	110355211
Bursitis	539.82	291.08	641	104393	129277	110354988
Mobility decreased	536.22	291.08	873	104161	236549	110247716
Blister	524.29	291.08	844	104190	226532	110257733
Impaired healing	523.19	291.08	780	104254	195937	110288328
Rheumatoid arthritis	510.07	291.08	973	104061	298640	110185625
Breast cancer stage III	504.72	291.08	490	104544	78627	110405638
Rheumatoid factor positive	492.52	291.08	616	104418	131024	110353241
Hypercholesterolaemia	485.12	291.08	511	104523	90326	110393939
Deep vein thrombosis postoperative	482.88	291.08	421	104613	58870	110425395
Peripheral venous disease	468.56	291.08	484	104550	83633	110400632
Wound infection	464.91	291.08	514	104520	95951	110388314
Arthropathy	444.74	291.08	897	104137	286625	110197640
Stomatitis	417.80	291.08	843	104191	269399	110214866
Sleep disorder	416.94	291.08	707	104327	197937	110286328
Cough	416.56	291.08	4	105030	461637	110022628
Autoimmune disorder	407.22	291.08	400	104634	65083	110419182
Swelling	401.24	291.08	970	104064	350071	110134194
Obesity	401.11	291.08	516	104518	112835	110371430
Hepatic enzyme increased	396.36	291.08	914	104120	319978	110164287
Gait inability	394.70	291.08	563	104471	135813	110348452
Ill-defined disorder	394.26	291.08	606	104428	156247	110328018
Hypotension	390.02	291.08	28	105006	523821	109960444
Dry mouth	377.16	291.08	679	104355	199269	110284996
Adjustment disorder with depressed mood	376.36	291.08	321	104713	43562	110440703
Alopecia	375.98	291.08	969	104065	363784	110120481
Wheezing	355.58	291.08	763	104271	254467	110229798
Lower limb fracture	355.27	291.08	397	104637	74951	110409314
Osteoarthritis	354.46	291.08	628	104406	181995	110302270
Road traffic accident	352.22	291.08	471	104563	106927	110377338
Sleep disorder due to general medical condition, insomnia type	350.59	291.08	466	104568	105177	110379088
Night sweats	348.47	291.08	526	104508	133457	110350808
Sciatica	348.06	291.08	434	104600	91965	110392300
Lower respiratory tract infection	344.69	291.08	732	104302	242374	110241891
Hypoaesthesia	333.28	291.08	844	104190	313379	110170886
Nail disorder	332.79	291.08	339	104695	57596	110426669
Discomfort	329.57	291.08	668	104366	214039	110270226
Inflammation	321.64	291.08	622	104412	192616	110291649
Maternal exposure during pregnancy	307.96	291.08	720	104314	254163	110230102
Blepharospasm	306.07	291.08	316	104718	54535	110429730
X-ray abnormal	302.96	291.08	267	104767	37850	110446415
Live birth	296.97	291.08	348	104686	69136	110415129
Urticaria	294.94	291.08	814	104220	318043	110166222
Dyspepsia	292.86	291.08	594	104440	190371	110293894

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12AA02	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS CALCIUM Calcium

Related Drugs by ATC class:

A12AA Calcium 11 drugs

calcium carbonatecalcium chloridecalcium citratecalcium glucoheptonatecalcium gluconatecalcium glycerylphosphatecalcium lactatecalcium lactate gluconatecalcium levulinatecalcium pangamatecalcium phosphate

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypocalcemia	indication	5291005

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
3CF7K0SD0Q	UNII
D03294	KEGG_DRUG
4020041	VUID
N0000179144	NUI
4020041	VANDF
C0061347	UMLSCUI
CHEBI:750927	CHEBI
CHEMBL2104594	ChEMBL_ID
6093269	PUBCHEM_CID
2890	INN_ID
C042131	MESH_SUPPLEMENTAL_RECORD_UI
218656	RXNORM
4335	MMSL
5173	MMSL
8444	MMSL
d03817	MMSL
000775	NDDF
32445001	SNOMEDCT_US

Pharmaceutical products:

None