calcium phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4441	7758-87-4

Description:

Molecule	Description
Synonyms: calcium phosphate tribasic calcium phosphate tricalcium phosphate	refers to unspecified salt; see other calcium phosphates Molecular weight: 310.17 Formula: Ca3O8P2 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 86.25 ALOGS: ROTB: None

Molecule

Description

Synonyms:

calcium phosphate
tribasic calcium phosphate
tricalcium phosphate

refers to unspecified salt; see other calcium phosphates

Molecular weight: 310.17
Formula: Ca3O8P2
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 86.25
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
2	g	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Atrioventricular conduction time shortened	18.97	16.14	3	4640	21	56287403
Blood electrolytes increased	17.93	16.14	3	4640	31	56287393
Rectal lesion	16.54	16.14	3	4640	51	56287373

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Regurgitation	47.64	20.84	12	1965	1337	31694030
Dyspepsia	45.06	20.84	27	1950	32526	31662841
Oropharyngeal discomfort	35.05	20.84	11	1966	2720	31692647
Vitamin B12 deficiency	32.31	20.84	11	1966	3508	31691859
Eructation	30.46	20.84	11	1966	4168	31691199

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Regurgitation	34.97	16.21	11	5372	2245	70920816
Dyspepsia	32.74	16.21	37	5346	89040	70834021
Vitamin B12 deficiency	31.10	16.21	13	5370	5959	70917102
Oropharyngeal discomfort	24.36	16.21	11	5372	6068	70916993
Eructation	22.17	16.21	12	5371	9748	70913313
Atrioventricular conduction time shortened	19.22	16.21	3	5380	21	70923040

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A12AA01	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS CALCIUM Calcium
MeSH PA	D001672	Biocompatible Materials

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypocalcemia	indication	5291005
Osteoporosis	indication	64859006	DOID:11476
Postmenopausal osteoporosis	indication	102447009
Pregnancy, function	indication	289908002
Breastfeeding (mother)	indication	413712001
Prevention of Fetal Neural Tube Defects during Pregnancy	off-label use
Poisoning by digitalis glycoside	contraindication	12876009
Peptic ulcer	contraindication	13200003	DOID:750
Constipation	contraindication	14760008	DOID:2089
Hyperphosphatemia	contraindication	20165001	DOID:0050459
Gastroenteritis	contraindication	25374005	DOID:2326
Hypervitaminosis D	contraindication	27712000	DOID:9971
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
Depressive disorder	contraindication	35489007
Hemosiderosis	contraindication	39011001	DOID:12119
Mental handicap	contraindication	47437004
Systemic lupus erythematosus	contraindication	55464009	DOID:9074
Schizophrenia	contraindication	58214004	DOID:5419
Hemolytic anemia	contraindication	61261009	DOID:583
Ulcerative colitis	contraindication	64766004	DOID:8577
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Hypercalciuria	contraindication	71938000
Diabetes mellitus	contraindication	73211009	DOID:9351
Autoimmune disease	contraindication	85828009
Kidney disease	contraindication	90708001	DOID:557
Kidney stone	contraindication	95570007
Neoplasm of prostate	contraindication	126906006	DOID:10283
Disease of liver	contraindication	235856003	DOID:409
Arteriosclerosis obliterans	contraindication	361133006	DOID:5160
Diverticular disease	contraindication	397881000
Hemochromatosis	contraindication	399187006	DOID:2352
Repeated Blood Transfusions	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4019973	VUID
N0000148058	NUI
1306-06-5	SECONDARY_CAS_RN
4019973	VANDF
4020044	VANDF
C0006711	UMLSCUI
CHEBI:9679	CHEBI
CHEMBL2107567	ChEMBL_ID
CHEMBL2106566	ChEMBL_ID
CHEMBL2218916	ChEMBL_ID
DB11348	DRUGBANK_ID
C020243	MESH_SUPPLEMENTAL_RECORD_UI
C018392	MESH_SUPPLEMENTAL_RECORD_UI
24456	PUBCHEM_CID
1919	RXNORM
4327	MMSL
4328	MMSL
NOCODE	MMSL
d03803	MMSL
005047	NDDF
419939009	SNOMEDCT_US
44044007	SNOMEDCT_US
91D9GV0Z28	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Prenaissance	HUMAN PRESCRIPTION DRUG LABEL	9	42192-341	CAPSULE, LIQUID FILLED	160 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Dairy Allergen Mix	HUMAN OTC DRUG LABEL	38	43742-1277	LIQUID	6 [hp_C]	ORAL	unapproved drug other	9 sections
CS Bone	HUMAN OTC DRUG LABEL	11	57955-0211	LIQUID	10 [hp_X]	ORAL	unapproved homeopathic	9 sections
Exoden Sensitive	HUMAN OTC DRUG LABEL	2	70602-006	PASTE	19 g	TOPICAL	unapproved drug other	8 sections
KUNDAL Sensitive Dental Care Tooth (Apple Chamomile Mint)	HUMAN OTC DRUG LABEL	1	74773-0040	PASTE	17 g	DENTAL	unapproved drug other	7 sections
DIO Enamel Coating Pen Pro Tooth	HUMAN OTC DRUG LABEL	3	75902-6001	PASTE, DENTIFRICE	20 g	DENTAL	unapproved drug other	7 sections