calcium phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4441 7758-87-4

Description:

MoleculeDescription

Synonyms:

  • calcium phosphate
  • tribasic calcium phosphate
  • tricalcium phosphate
refers to unspecified salt; see other calcium phosphates
  • Molecular weight: 310.17
  • Formula: Ca3O8P2
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 86.25
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Product dose omission issue 28.75 14.75 63 6251 291624 90330509
Intracranial pressure increased 20.96 14.75 10 6304 6801 90615332
Atrioventricular conduction time shortened 19.48 14.75 3 6311 21 90622112
Diarrhoea 18.45 14.75 120 6194 939070 89683063
Blood electrolytes increased 18.35 14.75 3 6311 32 90622101
Eye irritation 16.96 14.75 16 6298 33962 90588171
Rectal lesion 16.89 14.75 3 6311 54 90622079
Elliptocytosis 15.87 14.75 3 6311 77 90622056
Systemic lupus erythematosus 15.87 14.75 3 6311 361893 90260240
Defaecation urgency 15.74 14.75 8 6306 6234 90615899
Back pain 15.54 14.75 53 6261 317122 90305011

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Regurgitation 45.63 20.37 13 3171 1927 42616224
Dyspepsia 36.91 20.37 28 3156 41324 42576827
Eructation 32.38 20.37 13 3171 5473 42612678
Oropharyngeal discomfort 32.21 20.37 12 3172 4137 42614014
Vitamin B12 deficiency 30.21 20.37 12 3172 4910 42613241
Periarthritis 26.93 20.37 8 3176 1372 42616779
Testicular haemorrhage 22.84 20.37 5 3179 252 42617899

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Eructation 37.53 15.20 19 8042 14038 110567200
Regurgitation 34.53 15.20 12 8049 3473 110577765
Vitamin B12 deficiency 31.03 15.20 15 8046 10040 110571198
Product dose omission issue 29.04 15.20 69 7992 321713 110259525
Therapeutic reaction time decreased 26.27 15.20 11 8050 5268 110575970
Testicular haemorrhage 23.03 15.20 5 8056 248 110580990
Dyspepsia 22.97 15.20 46 8015 190919 110390319
Oropharyngeal discomfort 21.99 15.20 12 8049 10315 110570923
Atrioventricular conduction time shortened 19.34 15.20 3 8058 21 110581217
Abdominal distension 17.37 15.20 39 8022 175064 110406174
Vascular occlusion 17.18 15.20 6 8055 1761 110579477
Penile haemorrhage 16.69 15.20 5 8056 903 110580335
Intracranial pressure increased 16.44 15.20 10 8051 10525 110570713
Spirometry abnormal 16.36 15.20 8 8053 5489 110575749
Mite allergy 15.95 15.20 8 8053 5795 110575443
Groin infection 15.88 15.20 5 8056 1065 110580173
Mycotic allergy 15.75 15.20 8 8053 5946 110575292
Dust allergy 15.69 15.20 8 8053 5993 110575245
Blood electrolytes increased 15.52 15.20 3 8058 83 110581155
Thrombosis 15.30 15.20 28 8033 108634 110472604

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA01 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium
MeSH PA D001672 Biocompatible Materials

Related Drugs by ATC class:

A12AA Calcium 11 drugs
calcium carbonatecalcium chloridecalcium citratecalcium glubionatecalcium glucoheptonatecalcium gluconatecalcium glycerylphosphatecalcium lactatecalcium lactate gluconatecalcium levulinatecalcium pangamate

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Pregnancy, function indication 289908002
Breastfeeding (mother) indication 413712001
Prevention of Fetal Neural Tube Defects during Pregnancy off-label use
Poisoning by digitalis glycoside contraindication 12876009
Peptic ulcer contraindication 13200003 DOID:750
Constipation contraindication 14760008 DOID:2089
Hyperphosphatemia contraindication 20165001 DOID:0050459
Gastroenteritis contraindication 25374005 DOID:2326
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Depressive disorder contraindication 35489007
Hemosiderosis contraindication 39011001 DOID:12119
Mental handicap contraindication 47437004
Systemic lupus erythematosus contraindication 55464009 DOID:9074
Schizophrenia contraindication 58214004 DOID:5419
Hemolytic anemia contraindication 61261009 DOID:583
Ulcerative colitis contraindication 64766004 DOID:8577
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Diabetes mellitus contraindication 73211009 DOID:9351
Autoimmune disease contraindication 85828009
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Neoplasm of prostate contraindication 126906006 DOID:10283
Disease of liver contraindication 235856003 DOID:409
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Diverticular disease contraindication 397881000
Hemochromatosis contraindication 399187006 DOID:2352
Repeated Blood Transfusions contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019973 VUID
N0000148058 NUI
1306-06-5 SECONDARY_CAS_RN
4019973 VANDF
4020044 VANDF
C0006711 UMLSCUI
CHEBI:9679 CHEBI
CHEMBL2107567 ChEMBL_ID
CHEMBL2106566 ChEMBL_ID
CHEMBL2218916 ChEMBL_ID
DB11348 DRUGBANK_ID
C020243 MESH_SUPPLEMENTAL_RECORD_UI
C018392 MESH_SUPPLEMENTAL_RECORD_UI
24456 PUBCHEM_CID
1919 RXNORM
17895 MMSL
35088 MMSL
41493 MMSL
41494 MMSL
4327 MMSL
4328 MMSL
NOCODE MMSL
d03803 MMSL
005047 NDDF
256579008 SNOMEDCT_US
419939009 SNOMEDCT_US
44044007 SNOMEDCT_US
91D9GV0Z28 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CS Bone HUMAN OTC DRUG LABEL 11 57955-0211 LIQUID 10 [hp_X] ORAL unapproved homeopathic 9 sections
Exoden Sensitive HUMAN OTC DRUG LABEL 2 70602-006 PASTE 19 g TOPICAL unapproved drug other 8 sections
DIO Enamel Coating Pen Pro Tooth HUMAN OTC DRUG LABEL 3 75902-6001 PASTE, DENTIFRICE 20 g DENTAL unapproved drug other 7 sections
FRAICHE 5000 PREVI HUMAN PRESCRIPTION DRUG LABEL 2 83592-815 GEL 3 g TOPICAL unapproved drug other 8 sections
Teeth Whitening Kit HUMAN OTC DRUG LABEL 3 83778-002 CREAM 1 g TOPICAL unapproved drug other 13 sections
TeethWhitening Kit HUMAN OTC DRUG LABEL 3 83778-012 CREAM 1 g TOPICAL OTC Monograph Drug 11 sections
Teeth Whitening Kit HUMAN OTC DRUG LABEL 3 83812-001 LIQUID 1 g TOPICAL unapproved drug other 12 sections
Teeth Cleaning HUMAN OTC DRUG LABEL 2 84732-051 TABLET, CHEWABLE 1 mg DENTAL OTC Monograph Drug 9 sections