calcium phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4441 7758-87-4

Description:

MoleculeDescription

Synonyms:

  • calcium phosphate
  • tribasic calcium phosphate
  • tricalcium phosphate
refers to unspecified salt; see other calcium phosphates
  • Molecular weight: 310.17
  • Formula: Ca3O8P2
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 86.25
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Atrioventricular conduction time shortened 18.97 16.14 3 4640 21 56287403
Blood electrolytes increased 17.93 16.14 3 4640 31 56287393
Rectal lesion 16.54 16.14 3 4640 51 56287373

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Regurgitation 47.64 20.84 12 1965 1337 31694030
Dyspepsia 45.06 20.84 27 1950 32526 31662841
Oropharyngeal discomfort 35.05 20.84 11 1966 2720 31692647
Vitamin B12 deficiency 32.31 20.84 11 1966 3508 31691859
Eructation 30.46 20.84 11 1966 4168 31691199

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Regurgitation 34.97 16.21 11 5372 2245 70920816
Dyspepsia 32.74 16.21 37 5346 89040 70834021
Vitamin B12 deficiency 31.10 16.21 13 5370 5959 70917102
Oropharyngeal discomfort 24.36 16.21 11 5372 6068 70916993
Eructation 22.17 16.21 12 5371 9748 70913313
Atrioventricular conduction time shortened 19.22 16.21 3 5380 21 70923040

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA01 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium
MeSH PA D001672 Biocompatible Materials

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Pregnancy, function indication 289908002
Breastfeeding (mother) indication 413712001
Prevention of Fetal Neural Tube Defects during Pregnancy off-label use
Poisoning by digitalis glycoside contraindication 12876009
Peptic ulcer contraindication 13200003 DOID:750
Constipation contraindication 14760008 DOID:2089
Hyperphosphatemia contraindication 20165001 DOID:0050459
Gastroenteritis contraindication 25374005 DOID:2326
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Depressive disorder contraindication 35489007
Hemosiderosis contraindication 39011001 DOID:12119
Mental handicap contraindication 47437004
Systemic lupus erythematosus contraindication 55464009 DOID:9074
Schizophrenia contraindication 58214004 DOID:5419
Hemolytic anemia contraindication 61261009 DOID:583
Ulcerative colitis contraindication 64766004 DOID:8577
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Diabetes mellitus contraindication 73211009 DOID:9351
Autoimmune disease contraindication 85828009
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Neoplasm of prostate contraindication 126906006 DOID:10283
Disease of liver contraindication 235856003 DOID:409
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Diverticular disease contraindication 397881000
Hemochromatosis contraindication 399187006 DOID:2352
Repeated Blood Transfusions contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019973 VUID
N0000148058 NUI
1306-06-5 SECONDARY_CAS_RN
4019973 VANDF
4020044 VANDF
C0006711 UMLSCUI
CHEBI:9679 CHEBI
CHEMBL2107567 ChEMBL_ID
CHEMBL2106566 ChEMBL_ID
CHEMBL2218916 ChEMBL_ID
DB11348 DRUGBANK_ID
C020243 MESH_SUPPLEMENTAL_RECORD_UI
C018392 MESH_SUPPLEMENTAL_RECORD_UI
24456 PUBCHEM_CID
1919 RXNORM
4327 MMSL
4328 MMSL
NOCODE MMSL
d03803 MMSL
005047 NDDF
419939009 SNOMEDCT_US
44044007 SNOMEDCT_US
91D9GV0Z28 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Prenaissance HUMAN PRESCRIPTION DRUG LABEL 9 42192-341 CAPSULE, LIQUID FILLED 160 mg ORAL UNAPPROVED DRUG OTHER 10 sections
Dairy Allergen Mix HUMAN OTC DRUG LABEL 38 43742-1277 LIQUID 6 [hp_C] ORAL unapproved drug other 9 sections
CS Bone HUMAN OTC DRUG LABEL 11 57955-0211 LIQUID 10 [hp_X] ORAL unapproved homeopathic 9 sections
Exoden Sensitive HUMAN OTC DRUG LABEL 2 70602-006 PASTE 19 g TOPICAL unapproved drug other 8 sections
KUNDAL Sensitive Dental Care Tooth (Apple Chamomile Mint) HUMAN OTC DRUG LABEL 1 74773-0040 PASTE 17 g DENTAL unapproved drug other 7 sections
DIO Enamel Coating Pen Pro Tooth HUMAN OTC DRUG LABEL 3 75902-6001 PASTE, DENTIFRICE 20 g DENTAL unapproved drug other 7 sections