All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

magnesium oxide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4293	1309-48-4

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: magnesium oxide	Magnesium oxide (MgO). An inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses. Molecular weight: 40.30 Formula: MgO CLOGP: -1.32 LIPINSKI: None HAC: 1 HDO: 0 TPSA: 17.07 ALOGS: ROTB: 0

Drug dosage:

Dose	Unit	Route
7	g	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
June 22, 1982	FDA	BAXTER HLTHCARE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Pemphigus	1708.29	10.28	4403	539384	179323	62765912
Systemic lupus erythematosus	1613.67	10.28	4677	539110	204241	62740994
Glossodynia	1424.90	10.28	4050	539737	174826	62770409
Hand deformity	1159.87	10.28	3496	540291	155961	62789274
Arthropathy	1056.63	10.28	4394	539393	230398	62714837
Wound	959.42	10.28	3328	540459	159935	62785300
Abdominal discomfort	956.14	10.28	5332	538455	315553	62629682
Alopecia	943.68	10.28	5514	538273	332022	62613213
Completed suicide	876.63	10.28	108	543679	145565	62799670
Maternal exposure during pregnancy	864.25	10.28	3954	539833	216108	62729127
Rheumatoid arthritis	831.69	10.28	4330	539457	249489	62695746
Toxicity to various agents	784.87	10.28	583	543204	246667	62698568
Synovitis	769.27	10.28	3406	540381	183512	62761723
Anti-cyclic citrullinated peptide antibody positive	724.53	10.28	2417	541370	113795	62831440
Pericarditis	723.59	10.28	2625	541162	128954	62816281
Infusion related reaction	694.37	10.28	4025	539762	241496	62703739
Contraindicated product administered	690.66	10.28	3681	540106	213967	62731268
Discomfort	683.36	10.28	3043	540744	164331	62780904
Swelling	662.64	10.28	4330	539457	271048	62674187
Joint swelling	593.29	10.28	4813	538974	322853	62622382
Pain	496.80	10.28	8996	534791	731632	62213603
Death	484.18	10.28	1618	542169	372763	62572472
Rheumatoid factor positive	459.55	10.28	1679	542108	82727	62862508
Duodenal ulcer perforation	458.27	10.28	1715	542072	85494	62859741
Product use issue	441.58	10.28	3317	540470	217203	62728032
Helicobacter infection	441.33	10.28	1768	542019	91017	62854218
Intentional overdose	413.25	10.28	69	543718	74083	62871152
Drug interaction	406.63	10.28	845	542942	228286	62716949
Hepatic enzyme increased	389.65	10.28	3016	540771	199312	62745923
Drug abuse	385.73	10.28	76	543711	72442	62872793
Arthralgia	323.41	10.28	6751	537036	562959	62382276
Psoriatic arthropathy	300.77	10.28	1564	542223	89956	62855279
Musculoskeletal stiffness	293.39	10.28	2636	541151	181982	62763253
Therapeutic product effect decreased	290.15	10.28	2725	541062	190462	62754773
Drug intolerance	274.92	10.28	3934	539853	304727	62640508
Exposure during pregnancy	261.10	10.28	2248	541539	153299	62791936
Suicide attempt	250.19	10.28	104	543683	60814	62884421
Treatment failure	247.64	10.28	2701	541086	196342	62748893
Hip arthroplasty	228.91	10.28	911	542876	46735	62898500
Knee arthroplasty	224.18	10.28	990	542797	53216	62892019
Overdose	210.24	10.28	417	543370	114661	62830574
Device expulsion	204.86	10.28	28	543759	34894	62910341
Cardiac arrest	204.33	10.28	297	543490	92248	62852987
Rheumatic fever	199.68	10.28	815	542972	42296	62902939
Hypersensitivity	193.32	10.28	3551	540236	289134	62656101
Impaired healing	187.46	10.28	1511	542276	101031	62844204
Nasopharyngitis	176.75	10.28	3110	540677	251147	62694088
Sedation	174.96	10.28	57	543730	38752	62906483
Swollen joint count increased	174.49	10.28	691	543096	35363	62909872
Acute kidney injury	171.99	10.28	1436	542351	261979	62683256
Constipation	169.63	10.28	1178	542609	223765	62721470
Anxiety	166.13	10.28	1135	542652	216406	62728829
Disease progression	163.46	10.28	523	543264	122235	62823000
Hypotension	161.74	10.28	1523	542264	271081	62674154
Folliculitis	159.11	10.28	1090	542697	69227	62876008
Red blood cell sedimentation rate abnormal	159.06	10.28	450	543337	19332	62925903
Lactic acidosis	156.19	10.28	66	543721	38221	62907014
Asthenia	156.01	10.28	2329	541458	381275	62563960
Muscle injury	155.09	10.28	1025	542762	64320	62880915
Nausea	154.95	10.28	5874	537913	848597	62096638
Diarrhoea	152.88	10.28	4817	538970	710549	62234686
Tremor	149.77	10.28	603	543184	131636	62813599
Blister	149.69	10.28	1736	542051	128078	62817157
Drug hypersensitivity	145.03	10.28	1834	541953	308853	62636382
Neutropenia	142.73	10.28	895	542892	174110	62771125
Hyperhidrosis	142.47	10.28	461	543326	107375	62837860
Bradycardia	139.25	10.28	259	543528	72968	62872267
Agitation	137.65	10.28	186	543601	59571	62885664
Dyspnoea	137.60	10.28	4468	539319	656845	62288390
Sleep disorder due to general medical condition, insomnia type	136.21	10.28	839	542948	51378	62893857
Sickle cell anaemia with crisis	135.54	10.28	209	543578	5794	62939441
Electrocardiogram QT prolonged	127.54	10.28	195	543592	59335	62885900
Depressed level of consciousness	126.71	10.28	210	543577	61868	62883367
Irritable bowel syndrome	125.29	10.28	1166	542621	81246	62863989
Sopor	124.85	10.28	20	543767	22144	62923091
Intentional self-injury	124.44	10.28	33	543754	25654	62919581
Somnolence	122.09	10.28	962	542825	177723	62767512
C-reactive protein abnormal	120.45	10.28	741	543046	45355	62899880
Drug reaction with eosinophilia and systemic symptoms	120.40	10.28	70	543717	33766	62911469
Syncope	111.53	10.28	571	543216	116814	62828421
Cognitive disorder	110.98	10.28	192	543595	55623	62889612
Hyponatraemia	108.21	10.28	541	543246	111359	62833876
Febrile neutropenia	107.06	10.28	586	543201	117863	62827372
Lower respiratory tract infection	106.43	10.28	1658	542129	130649	62814586
Rash	106.26	10.28	5844	537943	555027	62390208
Renal failure	105.82	10.28	583	543204	117069	62828166
Dizziness	105.32	10.28	2840	540947	427085	62518150
Coma	105.26	10.28	248	543539	64116	62881119
Myalgia	103.30	10.28	782	543005	145747	62799488
Vision blurred	100.42	10.28	425	543362	91499	62853736
Blood cholesterol increased	100.24	10.28	1239	542548	92793	62852442
Neuropathy peripheral	99.65	10.28	568	543219	113099	62832136
Tachycardia	99.56	10.28	598	543189	117558	62827677
Balance disorder	99.36	10.28	379	543408	84043	62861192
Type 2 diabetes mellitus	99.27	10.28	908	542879	62960	62882275
Drug withdrawal syndrome	98.56	10.28	55	543732	27139	62918096
Condition aggravated	98.50	10.28	4298	539489	397919	62547316
Multiple sclerosis relapse	98.00	10.28	165	543622	48313	62896922
Respiratory arrest	97.06	10.28	82	543705	32563	62912672
Osteoarthritis	96.41	10.28	1244	542543	94099	62851136
Liver injury	95.89	10.28	864	542923	59656	62885579
Drug dependence	95.47	10.28	45	543742	24438	62920797
Serotonin syndrome	94.27	10.28	65	543722	28617	62916618
Feeling abnormal	92.69	10.28	818	542969	147574	62797661
Arthritis	91.83	10.28	1449	542338	114472	62830763
Intentional product use issue	87.87	10.28	1562	542225	126330	62818905
Vomiting	87.19	10.28	3912	539875	555705	62389530
Angioedema	86.53	10.28	175	543612	47790	62897445
Product quality issue	86.33	10.28	108	543679	35757	62909478
Fibromyalgia	85.86	10.28	1060	542727	79360	62865875
No adverse event	85.49	10.28	139	543648	41266	62903969
Drug resistance	85.13	10.28	45	543742	22888	62922347
Live birth	84.81	10.28	439	543348	25191	62920044
Chest discomfort	84.73	10.28	572	543215	109397	62835838
C-reactive protein increased	83.20	10.28	1205	542582	93502	62851733
Intentional product misuse	82.13	10.28	258	543529	60659	62884576
Pregnancy	80.93	10.28	567	543220	36269	62908966
Disturbance in attention	80.93	10.28	126	543661	38063	62907172
Metabolic acidosis	80.82	10.28	165	543622	44904	62900331
Cardio-respiratory arrest	80.79	10.28	254	543533	59705	62885530
Fatigue	79.30	10.28	8722	535065	879306	62065929
Seizure	78.97	10.28	740	543047	131894	62813341
Drug ineffective for unapproved indication	77.45	10.28	107	543680	33956	62911279
Blood pressure diastolic abnormal	73.02	10.28	282	543505	14260	62930975
Myocardial infarction	72.83	10.28	528	543259	99365	62845870
Stomatitis	72.75	10.28	1627	542160	137098	62808137
Ill-defined disorder	71.72	10.28	1040	542747	80715	62864520
Creatinine renal clearance decreased	71.68	10.28	25	543762	16283	62928952
Joint effusion	71.58	10.28	313	543474	16747	62928488
Product dose omission issue	71.33	10.28	1497	542290	232816	62712419
Asthma	71.18	10.28	723	543064	126838	62818397
Hepatocellular injury	70.68	10.28	78	543709	27303	62917932
Sedation complication	70.37	10.28	16	543771	13806	62931429
Blood pressure systolic abnormal	70.03	10.28	263	543524	13123	62932112
Rhabdomyolysis	69.76	10.28	172	543615	43779	62901456
Emotional distress	69.35	10.28	107	543680	32442	62912793
Red blood cell sedimentation rate increased	68.70	10.28	626	543161	43356	62901879
Flushing	67.54	10.28	372	543415	74715	62870520
Hypoglycaemia	67.27	10.28	275	543512	59790	62885445
Malignant neoplasm progression	66.88	10.28	420	543367	81701	62863534
Blood pressure fluctuation	65.75	10.28	646	543141	45671	62899564
Disability assessment scale score increased	65.33	10.28	107	543680	3126	62942109
Thrombocytopenia	65.04	10.28	907	542880	150250	62794985
Cholestasis	64.41	10.28	95	543692	29339	62915896
Ejection fraction decreased	64.08	10.28	58	543729	22274	62922961
Suicidal ideation	63.69	10.28	296	543491	62125	62883110
Neoplasm progression	63.11	10.28	136	543651	36292	62908943
Abortion spontaneous	63.03	10.28	650	543137	46545	62898690
Depression	62.87	10.28	1245	542542	195247	62749988
Orthostatic hypotension	62.64	10.28	135	543652	36025	62909210
Contusion	62.59	10.28	1706	542081	148338	62796897
Muscle spasticity	62.07	10.28	57	543730	21737	62923498
Anaphylactic reaction	61.94	10.28	323	543464	65777	62879458
Multiple organ dysfunction syndrome	60.37	10.28	265	543522	56487	62888748
Poisoning	60.22	10.28	21	543766	13679	62931556
Pulmonary fibrosis	59.85	10.28	562	543225	39247	62905988
Urticaria	59.76	10.28	1029	542758	164773	62780462
Foot deformity	59.59	10.28	426	543361	27427	62917808
Fluid retention	58.57	10.28	287	543500	59399	62885836
Hypermagnesaemia	56.50	10.28	55	543732	931	62944304
Bone pain	56.40	10.28	258	543529	54383	62890852
Encephalopathy	56.07	10.28	158	543629	38462	62906773
Muscle spasms	55.66	10.28	971	542816	155179	62790056
Hepatic failure	55.45	10.28	141	543646	35515	62909720
Cardiac failure	55.37	10.28	492	543295	88650	62856585
Juvenile idiopathic arthritis	55.32	10.28	101	543686	3225	62942010
Mydriasis	54.88	10.28	17	543770	11939	62933296
Insomnia	54.65	10.28	1414	542373	213838	62731397
Wrong technique in product usage process	54.36	10.28	312	543475	62028	62883207
Grip strength decreased	54.32	10.28	352	543435	21935	62923300
Hallucination	54.13	10.28	263	543524	54554	62890681
Blood pressure systolic increased	52.43	10.28	629	543158	46768	62898467
Device dislocation	52.40	10.28	87	543700	25618	62919617
Pulmonary embolism	51.67	10.28	696	543091	115988	62829247
Peripheral swelling	51.52	10.28	2778	541009	263164	62682071
Joint laxity	50.40	10.28	82	543705	2382	62942853
Blood glucose increased	50.40	10.28	466	543321	83290	62861945
Cardiac failure congestive	50.28	10.28	527	543260	91906	62853329
Bone erosion	50.24	10.28	291	543496	17426	62927809
Osteoporosis	50.12	10.28	729	543058	56609	62888626
Unresponsive to stimuli	50.09	10.28	137	543650	33679	62911556
Respiratory failure	49.78	10.28	595	543192	101263	62843972
Blood calcium decreased	49.01	10.28	95	543692	26356	62918879
Metastases to bone	48.82	10.28	65	543722	20954	62924281
Infection	48.46	10.28	2414	541373	226759	62718476
Drug tolerance decreased	48.25	10.28	285	543502	17188	62928047
Caesarean section	47.81	10.28	279	543508	16753	62928482
Headache	47.67	10.28	4724	539063	628517	62316718
Palpitations	47.66	10.28	679	543108	112091	62833144
Hypoxia	47.55	10.28	308	543479	59484	62885751
Speech disorder	47.40	10.28	183	543604	40446	62904789
Cerebrovascular accident	47.23	10.28	646	543141	107378	62837857
Joint destruction	47.15	10.28	139	543648	6113	62939122
Disorientation	47.13	10.28	176	543611	39276	62905959
Dysarthria	46.92	10.28	197	543590	42514	62902721
Basal cell carcinoma	46.59	10.28	404	543383	27587	62917648
Hepatotoxicity	46.40	10.28	162	543625	36879	62908356
Pain in jaw	46.32	10.28	203	543584	43293	62901942
Premature labour	46.21	10.28	221	543566	12283	62932952
Device difficult to use	46.20	10.28	26	543761	12770	62932465
Hyperglycaemia	46.06	10.28	193	543594	41674	62903561
Memory impairment	45.76	10.28	623	543164	103635	62841600
Blood pressure diastolic decreased	45.55	10.28	342	543445	22364	62922871
Joint range of motion decreased	45.40	10.28	451	543336	31977	62913258
Psychotic disorder	45.37	10.28	95	543692	25617	62919618
Product use in unapproved indication	45.28	10.28	1177	542610	177903	62767332
Accidental exposure to product	45.27	10.28	105	543682	27300	62917935
Diabetic ketoacidosis	45.04	10.28	66	543721	20439	62924796
Vertigo	44.87	10.28	314	543473	59573	62885662
Suspected suicide	44.46	10.28	3	543784	6565	62938670
Hypothermia	44.34	10.28	31	543756	13550	62931685
Polyneuropathy	44.16	10.28	36	543751	14553	62930682
Inflammation	44.08	10.28	968	542819	81305	62863930
Psoriasis	44.04	10.28	1015	542772	85942	62859293
Bronchospasm	43.75	10.28	50	543737	17230	62928005
COVID-19	43.68	10.28	693	543094	112410	62832825
Product administration error	43.65	10.28	78	543709	22319	62922916
Chest pain	43.25	10.28	1465	542322	214494	62730741
Polyarthritis	43.22	10.28	187	543600	9959	62935276
Loss of personal independence in daily activities	42.79	10.28	1114	542673	96176	62849059
Hypomania	42.54	10.28	3	543784	6327	62938908
Leukopenia	42.31	10.28	440	543347	76850	62868385
Neurotoxicity	42.11	10.28	50	543737	16940	62928295
Mental status changes	42.05	10.28	185	543602	39414	62905821
Respiratory disorder	41.25	10.28	183	543604	38899	62906336
Acute hepatic failure	41.24	10.28	58	543729	18269	62926966
Back pain	40.87	10.28	1847	541940	262298	62682937
Dysphagia	40.82	10.28	524	543263	88061	62857174
Weight increased	40.61	10.28	2672	541115	258120	62687115
Torsade de pointes	40.35	10.28	33	543754	13318	62931917
Rheumatoid nodule	40.02	10.28	268	543519	16887	62928348
Posterior reversible encephalopathy syndrome	39.92	10.28	54	543733	17291	62927944
Gestational diabetes	39.88	10.28	160	543627	8236	62936999
Drug ineffective	39.87	10.28	9799	533988	1034966	61910269
Sinusitis	39.87	10.28	2347	541440	224306	62720929
Hospitalisation	39.68	10.28	502	543285	84579	62860656
Anaphylactic shock	39.48	10.28	90	543697	23543	62921692
Drug level increased	39.28	10.28	85	543702	22651	62922584
Dysgeusia	39.01	10.28	237	543550	46473	62898762
Withdrawal syndrome	38.65	10.28	70	543717	19927	62925308
Lethargy	38.45	10.28	301	543486	55706	62889529
Disability	38.32	10.28	279	543508	18068	62927167
Palmar-plantar erythrodysaesthesia syndrome	38.16	10.28	88	543699	22927	62922308
Ventricular tachycardia	37.67	10.28	71	543716	19908	62925327
Neck deformity	37.31	10.28	66	543721	2055	62943180
Paraesthesia	37.24	10.28	1041	542746	155925	62789310
Respiratory distress	37.04	10.28	157	543630	33794	62911441
Coagulopathy	37.01	10.28	75	543712	20469	62924766
Rash erythematous	36.92	10.28	213	543574	42297	62902938
Disease recurrence	36.88	10.28	120	543667	27910	62917325
Depressed mood	36.75	10.28	198	543589	39993	62905242
Acute generalised exanthematous pustulosis	36.68	10.28	25	543762	11074	62934161
Dyspnoea exertional	36.49	10.28	335	543452	59967	62885268
Extrapyramidal disorder	36.36	10.28	36	543751	13248	62931987
Dry skin	36.19	10.28	312	543475	56575	62888660
Muscle twitching	36.12	10.28	71	543716	19597	62925638
Haemorrhage	36.07	10.28	341	543446	60681	62884554
Chronic kidney disease	36.02	10.28	234	543553	45164	62900071
Tuberculosis	35.69	10.28	190	543597	11021	62934214
Hemiparesis	35.48	10.28	93	543694	23189	62922046
Respiratory depression	35.47	10.28	39	543748	13676	62931559
Injection site pruritus	35.34	10.28	563	543224	44553	62900682
Foetal exposure during pregnancy	35.28	10.28	424	543363	31538	62913697
Irritability	34.92	10.28	146	543641	31548	62913687
Lip swelling	34.91	10.28	142	543645	30921	62914314
Accidental overdose	34.85	10.28	94	543693	23215	62922020
Arrhythmia	34.82	10.28	188	543599	37952	62907283
Shock	34.80	10.28	95	543692	23368	62921867
Abnormal behaviour	34.67	10.28	83	543704	21343	62923892
Adverse event	34.65	10.28	790	542997	66769	62878466
Multiple fractures	34.56	10.28	156	543631	8462	62936773
Skin exfoliation	34.29	10.28	222	543565	42880	62902355
Dehydration	34.22	10.28	1178	542609	172176	62773059
Panic attack	34.19	10.28	89	543698	22242	62922993
Loss of consciousness	34.06	10.28	761	543026	117360	62827875
Exposure to toxic agent	33.93	10.28	4	543783	5583	62939652
Anaemia	33.86	10.28	2113	541674	291317	62653918
Prescribed underdose	33.71	10.28	396	543391	29293	62915942
Obstructive airways disorder	33.64	10.28	80	543707	20619	62924616
Chills	33.39	10.28	728	543059	112650	62832585
Thrombotic microangiopathy	33.31	10.28	25	543762	10536	62934699
Immune reconstitution inflammatory syndrome	33.14	10.28	6	543781	6078	62939157
Metastases to liver	32.65	10.28	99	543688	23540	62921695
Deep vein thrombosis	32.50	10.28	513	543274	83287	62861948
Hyperkalaemia	32.42	10.28	302	543485	53901	62891334
Dystonia	31.83	10.28	43	543744	13776	62931459
Infective pulmonary exacerbation of cystic fibrosis	31.71	10.28	18	543769	8799	62936436
Restlessness	31.64	10.28	137	543650	29316	62915919
Joint dislocation	31.63	10.28	272	543515	18528	62926707
Forced expiratory volume decreased	31.60	10.28	3	543784	4965	62940270
Swollen tongue	31.51	10.28	172	543615	34628	62910607
Nodule	31.19	10.28	296	543491	20730	62924505
Haematotoxicity	31.14	10.28	21	543766	9355	62935880
Atrial fibrillation	30.97	10.28	761	543026	115875	62829360
Laryngitis	30.96	10.28	250	543537	16717	62928518
Injection site erythema	30.87	10.28	932	542855	82242	62862993
International normalised ratio increased	30.72	10.28	252	543535	46173	62899062
Crying	30.66	10.28	100	543687	23243	62921992
Fear	30.64	10.28	55	543732	15711	62929524
Nightmare	30.55	10.28	75	543712	19119	62926116
Substance abuse	30.32	10.28	3	543784	4804	62940431
Eosinophilia	30.23	10.28	97	543690	22659	62922576
Cytomegalovirus infection	30.20	10.28	86	543701	20866	62924369
Bradyphrenia	30.17	10.28	11	543776	6969	62938266
Maternal exposure before pregnancy	30.02	10.28	137	543650	7466	62937769
Maternal drugs affecting foetus	29.96	10.28	106	543681	5136	62940099
Product adhesion issue	29.62	10.28	3	543784	4716	62940519
Pancreatitis acute	29.40	10.28	126	543661	27040	62918195
Enthesopathy	28.81	10.28	148	543639	8466	62936769
Uterine perforation	28.40	10.28	12	543775	6951	62938284
Heart rate decreased	28.32	10.28	548	543239	45012	62900223
Aphasia	28.31	10.28	166	543621	32834	62912401
Femur fracture	28.30	10.28	509	543278	41247	62903988
Visual impairment	27.91	10.28	532	543255	83914	62861321
Complication of device insertion	27.84	10.28	15	543772	7549	62937686
Cardiogenic shock	27.81	10.28	71	543716	17861	62927374
Cough	27.67	10.28	2145	541642	290598	62654637
Agranulocytosis	27.56	10.28	116	543671	25018	62920217
Latent tuberculosis	27.53	10.28	66	543721	2561	62942674
Blood pressure diastolic increased	27.47	10.28	163	543624	9847	62935388
Diabetes mellitus inadequate control	27.44	10.28	55	543732	15071	62930164
Pulmonary arterial hypertension	27.44	10.28	100	543687	22477	62922758
Post transplant lymphoproliferative disorder	27.32	10.28	5	543782	5026	62940209
Cholecystitis chronic	27.31	10.28	29	543758	10332	62934903
Complication associated with device	27.29	10.28	66	543721	16912	62928323
Ventricular septal defect	27.18	10.28	91	543696	4287	62940948
Ischaemic stroke	27.16	10.28	72	543715	17885	62927350
Akathisia	27.15	10.28	23	543764	9123	62936112
Status epilepticus	27.11	10.28	56	543731	15177	62930058
Fall	26.96	10.28	2945	540842	389389	62555846
Myelosuppression	26.86	10.28	108	543679	23595	62921640
Skin ulcer	26.84	10.28	518	543269	42527	62902708
Device use error	26.79	10.28	8	543779	5753	62939482
Infusion site pain	26.78	10.28	66	543721	16803	62928432
Wheelchair user	26.56	10.28	116	543671	6203	62939032
Tenderness	26.46	10.28	303	543484	22275	62922960
Breast cancer stage I	26.34	10.28	13	543774	6876	62938359
Feeling hot	26.21	10.28	290	543497	50064	62895171
Peripheral venous disease	26.08	10.28	224	543563	15253	62929982
Haematoma	25.87	10.28	183	543604	34637	62910598
Venoocclusive liver disease	25.84	10.28	5	543782	4830	62940405
Blood creatine phosphokinase increased	25.62	10.28	154	543633	30276	62914959
Limb deformity	25.57	10.28	84	543703	3918	62941317
Anhedonia	25.42	10.28	34	543753	10940	62934295
General physical health deterioration	25.42	10.28	2029	541758	199373	62745862
Personality disorder	25.38	10.28	9	543778	5802	62939433
Dyskinesia	25.37	10.28	165	543622	31837	62913398
Neuroleptic malignant syndrome	25.33	10.28	40	543747	12016	62933219
Paradoxical drug reaction	25.15	10.28	3	543784	4149	62941086
Small for dates baby	25.12	10.28	80	543707	3671	62941564
Mania	25.08	10.28	42	543745	12325	62932910
Schizophrenia	24.98	10.28	29	543758	9923	62935312
Second primary malignancy	24.86	10.28	19	543768	7934	62937301
Joint stiffness	24.82	10.28	500	543287	41369	62903866
Ankylosing spondylitis	24.65	10.28	164	543623	10310	62934925
Macular degeneration	24.62	10.28	116	543671	24260	62920975
Lupus-like syndrome	24.54	10.28	219	543568	15076	62930159
Multiple allergies	24.34	10.28	51	543736	13751	62931484
Temperature regulation disorder	24.33	10.28	11	543776	6121	62939114
Face oedema	24.25	10.28	90	543697	20122	62925113
Malignant mediastinal neoplasm	24.17	10.28	44	543743	1402	62943833
Pulmonary oedema	24.03	10.28	328	543459	54545	62890690
Obesity	23.92	10.28	375	543412	29577	62915658
Facet joint syndrome	23.88	10.28	182	543605	11956	62933279
Angina pectoris	23.88	10.28	155	543632	29923	62915312
Abdominal distension	23.85	10.28	562	543225	86053	62859182
Acute respiratory failure	23.82	10.28	185	543602	34300	62910935
Pancreatitis	23.79	10.28	287	543500	48768	62896467
Brain oedema	23.76	10.28	54	543733	14141	62931094
Sinus tachycardia	23.63	10.28	117	543670	24151	62921084
Off label use	23.62	10.28	5265	538522	669197	62276038
Premature rupture of membranes	23.59	10.28	95	543692	4898	62940337
Febrile bone marrow aplasia	23.54	10.28	17	543770	7308	62937927
Ventricular fibrillation	23.42	10.28	41	543746	11826	62933409
Transplant rejection	23.38	10.28	35	543752	10745	62934490
Unevaluable event	23.28	10.28	305	543482	51081	62894154
Hot flush	23.05	10.28	304	543483	50855	62894380
Gastrointestinal disorder	23.05	10.28	1359	542428	129880	62815355
Mental disorder	22.98	10.28	129	543658	25790	62919445
Infusion site swelling	22.91	10.28	30	543757	9740	62935495
Tenosynovitis	22.90	10.28	199	543588	13596	62931639
Tachypnoea	22.81	10.28	74	543713	17228	62928007
Acute graft versus host disease	22.80	10.28	5	543782	4423	62940812
Tenosynovitis stenosans	22.76	10.28	72	543715	3292	62941943
Body temperature decreased	22.62	10.28	270	543517	20049	62925186
Paralysis	22.60	10.28	31	543756	9869	62935366
Multiple-drug resistance	22.59	10.28	8	543779	5162	62940073
Injection site reaction	22.58	10.28	659	543128	57865	62887370
Aggression	22.47	10.28	114	543673	23384	62921851
Miosis	22.44	10.28	18	543769	7335	62937900
Renal impairment	22.23	10.28	581	543206	87774	62857461
Tardive dyskinesia	22.18	10.28	24	543763	8478	62936757
Pre-eclampsia	22.10	10.28	144	543643	8989	62936246
Gamma-glutamyltransferase increased	21.93	10.28	186	543601	33845	62911390
Red blood cell sedimentation rate	21.86	10.28	91	543696	4763	62940472
Psychomotor hyperactivity	21.82	10.28	36	543751	10627	62934608
Retinitis	21.81	10.28	108	543679	6088	62939147
Influenza like illness	21.77	10.28	422	543365	66402	62878833
Asphyxia	21.69	10.28	13	543774	6168	62939067
Lip dry	21.58	10.28	215	543572	15255	62929980
Affective disorder	21.46	10.28	13	543774	6133	62939102
Dislocation of vertebra	21.42	10.28	137	543650	8498	62936737
Pulmonary tuberculosis	21.39	10.28	86	543701	4431	62940804
Dysmorphism	21.23	10.28	55	543732	2241	62942994
Adjustment disorder with depressed mood	21.21	10.28	155	543632	10049	62935186
Localised infection	21.09	10.28	370	543417	29840	62915395
Hyperlipidaemia	21.04	10.28	91	543696	19480	62925755
Nervousness	21.02	10.28	167	543620	30812	62914423
Prescribed overdose	20.96	10.28	410	543377	33743	62911492
Coronary artery disease	20.85	10.28	177	543610	32200	62913035
Myoclonus	20.83	10.28	68	543719	15800	62929435
Labelled drug-drug interaction medication error	20.82	10.28	53	543734	13346	62931889
Smear cervix abnormal	20.80	10.28	64	543723	2882	62942353
Lymphoedema	20.79	10.28	43	543744	11649	62933586
Mobility decreased	20.78	10.28	1252	542535	119907	62825328
Nasal polyps	20.77	10.28	13	543774	6026	62939209
Complication of device removal	20.75	10.28	9	543778	5133	62940102
Infusion site erythema	20.73	10.28	43	543744	11636	62933599
Multiple sclerosis	20.70	10.28	123	543664	24249	62920986
Jaundice	20.64	10.28	156	543631	29095	62916140
Cyanosis	20.59	10.28	75	543712	16860	62928375
Maternal exposure timing unspecified	20.48	10.28	117	543670	6970	62938265
Anti-cyclic citrullinated peptide antibody	20.48	10.28	113	543674	6645	62938590
Bradypnoea	20.46	10.28	3	543784	3547	62941688
Leukocytosis	20.41	10.28	134	543653	25801	62919434
Sexual dysfunction	20.37	10.28	6	543781	4353	62940882
Pathogen resistance	20.37	10.28	15	543772	6383	62938852
Musculoskeletal pain	20.30	10.28	976	542811	91301	62853934
Tinnitus	20.25	10.28	201	543586	35427	62909808
Visual acuity reduced	20.25	10.28	107	543680	21719	62923516
Synovial fluid analysis	20.20	10.28	56	543731	2377	62942858
Mood altered	20.18	10.28	62	543725	14681	62930554
Urinary incontinence	20.18	10.28	176	543611	31838	62913397
Hereditary angioedema	20.12	10.28	21	543766	7541	62937694
Therapeutic response decreased	20.10	10.28	679	543108	60846	62884389
Therapy partial responder	19.99	10.28	38	543749	10620	62934615
Abdominal pain	19.84	10.28	2205	541582	291251	62653984
Injection site swelling	19.84	10.28	541	543246	47031	62898204
Haemophagocytic lymphohistiocytosis	19.83	10.28	38	543749	10589	62934646
Wound infection	19.82	10.28	275	543512	21135	62924100
Dermatitis atopic	19.74	10.28	33	543754	9691	62935544
Cardiotoxicity	19.69	10.28	26	543761	8412	62936823
Rotator cuff repair	19.61	10.28	51	543736	2083	62943152
Hepatic cytolysis	19.55	10.28	67	543720	15340	62929895
Cytopenia	19.52	10.28	44	543743	11557	62933678
Abdominal pain upper	19.43	10.28	1513	542274	204931	62740304
Toxic epidermal necrolysis	19.39	10.28	132	543655	25202	62920033
Cardiomyopathy	19.37	10.28	81	543706	17503	62927732
Placental disorder	19.35	10.28	41	543746	1463	62943772
Device breakage	19.24	10.28	44	543743	11498	62933737
Hypokalaemia	19.19	10.28	711	543076	103093	62842142
Product prescribing error	19.13	10.28	139	543648	26150	62919085
Muscle rigidity	19.04	10.28	44	543743	11456	62933779
Neck mass	19.02	10.28	71	543716	3532	62941703
Circulatory collapse	19.01	10.28	110	543677	21828	62923407
Product complaint	18.89	10.28	52	543735	12757	62932478
Body height below normal	18.87	10.28	51	543736	2132	62943103
Progressive multifocal leukoencephalopathy	18.87	10.28	53	543734	12918	62932317
Loose body in joint	18.85	10.28	37	543750	1249	62943986
Pancytopenia	18.82	10.28	1013	542774	95920	62849315
Anger	18.80	10.28	50	543737	12406	62932829
Cardiac disorder	18.73	10.28	314	543473	50502	62894733
Body temperature increased	18.64	10.28	216	543571	36976	62908259
Sepsis	18.63	10.28	1097	542690	152026	62793209
Food allergy	18.58	10.28	44	543743	11357	62933878
Swelling face	18.56	10.28	408	543379	63067	62882168
Rhinitis allergic	18.52	10.28	46	543741	11681	62933554
Toxic skin eruption	18.49	10.28	53	543734	12832	62932403
Product preparation error	18.48	10.28	15	543772	6077	62939158
Sleep apnoea syndrome	18.43	10.28	160	543627	28973	62916262
Pallor	18.41	10.28	170	543617	30398	62914837
Throat tightness	18.39	10.28	131	543656	24756	62920479
Schizoaffective disorder	18.38	10.28	4	543783	3558	62941677
Developmental hip dysplasia	18.35	10.28	38	543749	1334	62943901
Paranoia	18.30	10.28	46	543741	11633	62933602
Muscular weakness	18.20	10.28	859	542928	121494	62823741
Device issue	18.15	10.28	124	543663	23657	62921578
Rebound effect	18.14	10.28	8	543779	4518	62940717
Synovial cyst	18.11	10.28	152	543635	10281	62934954
Rash maculo-papular	18.10	10.28	180	543607	31716	62913519
Coordination abnormal	18.09	10.28	59	543728	13714	62931521
Catheter site erythema	18.04	10.28	7	543780	4269	62940966
Haematocrit decreased	18.03	10.28	453	543334	38887	62906348
Respiration abnormal	18.02	10.28	17	543770	6400	62938835
Foetal anticonvulsant syndrome	17.97	10.28	24	543763	581	62944654
Synovial disorder	17.91	10.28	48	543739	1997	62943238
Clostridium difficile colitis	17.90	10.28	103	543684	20466	62924769
Metastases to lung	17.89	10.28	53	543734	12697	62932538
Deep vein thrombosis postoperative	17.84	10.28	162	543625	11207	62934028
Catatonia	17.81	10.28	8	543779	4469	62940766
Spinal stenosis	17.81	10.28	201	543586	14724	62930511
Pregnancy with contraceptive device	17.74	10.28	9	543778	4685	62940550
Pulseless electrical activity	17.73	10.28	23	543764	7498	62937737
Interstitial lung disease	17.71	10.28	673	543114	61235	62884000
Pseudomonas infection	17.70	10.28	44	543743	11169	62934066
Hemiplegia	17.69	10.28	33	543754	9290	62935945
Renal tubular necrosis	17.68	10.28	48	543739	11830	62933405
Liver disorder	17.67	10.28	593	543194	53094	62892141
Cerebral haemorrhage	17.61	10.28	173	543614	30556	62914679
Stress cardiomyopathy	17.45	10.28	34	543753	9416	62935819
Sinus bradycardia	17.32	10.28	65	543722	14486	62930749
Ascites	17.28	10.28	245	543542	40483	62904752
Rheumatoid lung	17.22	10.28	72	543715	3776	62941459
Inappropriate antidiuretic hormone secretion	17.18	10.28	71	543716	15391	62929844
Ketoacidosis	17.14	10.28	8	543779	4370	62940865
Fracture	17.11	10.28	249	543538	19335	62925900
Sensitisation	17.08	10.28	4	543783	3382	62941853
Skin papilloma	17.06	10.28	86	543701	4883	62940352
Incorrect product administration duration	16.93	10.28	47	543740	11499	62933736
Threatened labour	16.90	10.28	28	543759	826	62944409
Device related infection	16.86	10.28	124	543663	23268	62921967
Sleep disorder due to a general medical condition	16.86	10.28	51	543736	12137	62933098
Product substitution issue	16.82	10.28	75	543712	15921	62929314
Abnormal dreams	16.81	10.28	41	543746	10475	62934760
Acute myocardial infarction	16.72	10.28	185	543602	31939	62913296
Polyhydramnios	16.66	10.28	50	543737	2221	62943014
Mucosal inflammation	16.64	10.28	292	543495	46636	62898599
Blood bilirubin increased	16.62	10.28	221	543566	36919	62908316
Acute coronary syndrome	16.56	10.28	39	543748	10087	62935148
Renal injury	16.55	10.28	35	543752	9404	62935831
Breast cancer female	16.51	10.28	60	543727	13499	62931736
Laryngospasm	16.47	10.28	3	543784	3025	62942210
Malignant melanoma	16.41	10.28	159	543628	11197	62934038
Acute chest syndrome	16.36	10.28	27	543760	794	62944441
Clear cell renal cell carcinoma	16.31	10.28	38	543749	1447	62943788
Product administered to patient of inappropriate age	16.21	10.28	4	543783	3264	62941971
Arthritis infective	16.21	10.28	103	543684	6375	62938860
Trigeminal neuralgia	16.16	10.28	5	543782	3514	62941721
Blood parathyroid hormone decreased	16.13	10.28	141	543646	9650	62935585
Hallucination, auditory	16.12	10.28	56	543731	12768	62932467
Congenital arterial malformation	16.03	10.28	17	543770	320	62944915
Eye pruritus	15.97	10.28	94	543693	18577	62926658
Atrial septal defect	15.95	10.28	108	543679	6830	62938405
Blood creatinine increased	15.94	10.28	603	543184	87241	62857994
Pulmonary hypertension	15.86	10.28	223	543564	36900	62908335
Stevens-Johnson syndrome	15.80	10.28	137	543650	24813	62920422
Human antichimeric antibody positive	15.79	10.28	41	543746	1673	62943562
Genital haemorrhage	15.72	10.28	24	543763	7308	62937927
Intracranial pressure increased	15.70	10.28	13	543774	5214	62940021
Presyncope	15.68	10.28	157	543630	27628	62917607
Anuria	15.64	10.28	55	543732	12496	62932739
Acidosis	15.54	10.28	47	543740	11186	62934049
Middle insomnia	15.36	10.28	56	543731	12587	62932648
Melaena	15.36	10.28	176	543611	30189	62915046
Osteonecrosis of jaw	15.36	10.28	210	543577	34913	62910322
Blood alkaline phosphatase increased	15.35	10.28	267	543520	42700	62902535
Multiple drug therapy	15.33	10.28	6	543781	3640	62941595
Breast feeding	15.33	10.28	27	543760	838	62944397
Haemorrhage intracranial	15.29	10.28	61	543726	13358	62931877
Hepatitis cholestatic	15.24	10.28	22	543765	6856	62938379
Bundle branch block left	15.23	10.28	23	543764	7036	62938199
Granuloma skin	15.22	10.28	124	543663	8313	62936922
Hypercholesterolaemia	15.15	10.28	262	543525	21072	62924163
Cytokine release syndrome	15.12	10.28	67	543720	14247	62930988
Glycosylated haemoglobin increased	15.01	10.28	55	543732	12343	62932892
Oedema peripheral	14.98	10.28	1408	542379	188103	62757132
Parkinsonism	14.94	10.28	43	543744	10396	62934839
Cushingoid	14.93	10.28	124	543663	8361	62936874
Gestational hypertension	14.79	10.28	50	543737	2367	62942868
Hypertransaminasaemia	14.78	10.28	21	543766	6588	62938647
Jaundice cholestatic	14.73	10.28	25	543762	7299	62937936
Infusion site pruritus	14.70	10.28	18	543769	6017	62939218
Myopathy	14.66	10.28	48	543739	11143	62934092
Graft versus host disease	14.63	10.28	22	543765	6741	62938494
Erythema	14.58	10.28	1301	542486	174450	62770785
Atrioventricular block	14.57	10.28	27	543760	7620	62937615
Hallucination, visual	14.54	10.28	101	543686	19197	62926038
Heart rate increased	14.54	10.28	659	543128	93579	62851656
Restless legs syndrome	14.46	10.28	96	543691	18435	62926800
Colitis	14.45	10.28	311	543476	48217	62897018
Exostosis	14.40	10.28	224	543563	17638	62927597
Respiratory acidosis	14.37	10.28	22	543765	6693	62938542
Acute myeloid leukaemia	14.32	10.28	87	543700	17060	62928175
Wrong product administered	14.25	10.28	19	543768	6122	62939113
Embedded device	14.21	10.28	6	543781	3477	62941758
Thrombosis	14.20	10.28	434	543353	64321	62880914
Lupus vulgaris	14.20	10.28	94	543693	5900	62939335
Aspergillus infection	14.19	10.28	30	543757	8063	62937172
Neurologic neglect syndrome	14.16	10.28	3	543784	2718	62942517
Epistaxis	14.15	10.28	495	543292	72230	62873005
Antinuclear antibody positive	14.13	10.28	117	543670	7882	62937353
Atrioventricular block complete	14.13	10.28	31	543756	8220	62937015
Eating disorder	14.10	10.28	100	543687	18916	62926319
Ageusia	14.06	10.28	65	543722	13663	62931572
Eye swelling	13.98	10.28	134	543653	23784	62921451
Hypomagnesaemia	13.98	10.28	168	543619	28569	62916666
Occult blood	13.97	10.28	33	543754	1268	62943967
Human herpesvirus 6 infection	13.95	10.28	4	543783	2953	62942282
Fear of injection	13.86	10.28	107	543680	7057	62938178
Bone lesion	13.85	10.28	18	543769	5863	62939372
Personality change	13.85	10.28	24	543763	6949	62938286
Skin toxicity	13.82	10.28	12	543775	4702	62940533
Stillbirth	13.73	10.28	102	543685	6648	62938587
Colitis microscopic	13.71	10.28	38	543749	9301	62935934
Drug abuser	13.70	10.28	4	543783	2919	62942316
Reversible cerebral vasoconstriction syndrome	13.69	10.28	3	543784	2655	62942580
Pruritus genital	13.66	10.28	3	543784	2651	62942584
Drug screen positive	13.65	10.28	7	543780	3622	62941613
Dermatitis exfoliative	13.60	10.28	16	543771	5443	62939792
Transplant dysfunction	13.57	10.28	13	543774	4859	62940376
Transaminases increased	13.55	10.28	188	543599	31179	62914056
Anti-neutrophil cytoplasmic antibody positive vasculitis	13.53	10.28	4	543783	2895	62942340
Motor dysfunction	13.52	10.28	47	543740	10714	62934521
Exomphalos	13.44	10.28	20	543767	537	62944698
Postoperative wound infection	13.43	10.28	148	543639	10777	62934458
Abortion incomplete	13.42	10.28	5	543782	3126	62942109
Premature delivery	13.38	10.28	347	543440	29934	62915301
Silent thyroiditis	13.36	10.28	9	543778	87	62945148
Blood iron increased	13.31	10.28	36	543751	1506	62943729
Acute respiratory distress syndrome	13.28	10.28	133	543654	23401	62921834
Flatulence	13.26	10.28	213	543574	34489	62910746
Rectal haemorrhage	13.25	10.28	319	543468	48711	62896524
Antibody test positive	13.19	10.28	52	543735	2655	62942580
Neutrophilia	13.18	10.28	11	543776	4395	62940840
Epstein-Barr virus infection	13.17	10.28	31	543756	8019	62937216
Electrocardiogram QRS complex prolonged	13.15	10.28	19	543768	5919	62939316
Cholinergic syndrome	13.07	10.28	19	543768	499	62944736
Gastrointestinal haemorrhage	13.06	10.28	565	543222	80611	62864624
Application site pain	13.06	10.28	10	543777	4172	62941063
Gastroenteritis viral	13.05	10.28	280	543507	23420	62921815
Fracture delayed union	13.01	10.28	48	543739	2374	62942861
Gastroschisis	12.90	10.28	17	543770	406	62944829
Acute pulmonary oedema	12.89	10.28	32	543755	8126	62937109
Blood glucose decreased	12.84	10.28	116	543671	20836	62924399
Crohn's disease	12.84	10.28	79	543708	4834	62940401
Short stature	12.83	10.28	22	543765	668	62944567
Ataxia	12.74	10.28	77	543710	15118	62930117
Scleritis	12.73	10.28	73	543714	4355	62940880
Haemoglobin decreased	12.71	10.28	1428	542359	144057	62801178
Pelvic pain	12.69	10.28	66	543721	13453	62931782
Tumour marker increased	12.69	10.28	14	543773	4901	62940334
Blood test abnormal	12.68	10.28	80	543707	15549	62929686
Bursitis	12.67	10.28	411	543376	36630	62908605
Injection site rash	12.64	10.28	229	543558	18580	62926655
Skin burning sensation	12.62	10.28	61	543726	12673	62932562
Affect lability	12.51	10.28	51	543736	11100	62934135
Extra dose administered	12.48	10.28	22	543765	6328	62938907
Haemoptysis	12.47	10.28	172	543615	28554	62916681
Post-traumatic stress disorder	12.44	10.28	16	543771	5235	62940000
Metastases to central nervous system	12.29	10.28	64	543723	13041	62932194
Hallucinations, mixed	12.20	10.28	14	543773	4815	62940420
Non-small cell lung cancer	12.19	10.28	62	543725	3533	62941702
Atrial tachycardia	12.18	10.28	11	543776	4229	62941006
Proteinuria	12.18	10.28	105	543682	19040	62926195
Increased appetite	12.14	10.28	42	543745	9588	62935647
Inadequate analgesia	12.12	10.28	5	543782	2938	62942297
Skin plaque	12.10	10.28	34	543753	8286	62936949
Malaise	12.10	10.28	3274	540513	412680	62532555
Defaecation disorder	12.09	10.28	23	543764	758	62944477
Bundle branch block right	12.08	10.28	15	543772	4983	62940252
Lymphatic fistula	11.99	10.28	23	543764	763	62944472
Endophthalmitis	11.99	10.28	8	543779	3584	62941651
Oliguria	11.94	10.28	39	543748	9062	62936173
Haemorrhage in pregnancy	11.94	10.28	40	543747	1885	62943350
Rales	11.91	10.28	62	543725	12635	62932600
Disturbance in social behaviour	11.90	10.28	10	543777	3983	62941252
Lacrimation increased	11.89	10.28	116	543671	20515	62924720
Toxic encephalopathy	11.87	10.28	24	543763	6555	62938680
Adenovirus infection	11.86	10.28	8	543779	3563	62941672
Haematemesis	11.84	10.28	186	543601	30226	62915009
Ejection fraction	11.83	10.28	3	543784	2403	62942832
Pharyngeal oedema	11.78	10.28	69	543718	13652	62931583
Hypoventilation	11.77	10.28	14	543773	4740	62940495
Speech disorder developmental	11.76	10.28	21	543766	659	62944576
Muscle contractions involuntary	11.72	10.28	3	543784	2389	62942846
Congenital cerebral cyst	11.72	10.28	13	543774	258	62944977
Joint noise	11.72	10.28	71	543716	4321	62940914
Panniculitis	11.69	10.28	149	543638	11236	62933999
Oligoarthritis	11.68	10.28	19	543768	552	62944683
Hepatic function abnormal	11.65	10.28	408	543379	36734	62908501
Herpes zoster	11.60	10.28	838	542949	81624	62863611
Drug eruption	11.59	10.28	325	543462	28369	62916866
Rash macular	11.59	10.28	136	543651	23228	62922007
Hypertelorism	11.57	10.28	17	543770	451	62944784
Troponin increased	11.54	10.28	46	543741	10075	62935160
Ankle arthroplasty	11.54	10.28	38	543749	1775	62943460
Autism spectrum disorder	11.52	10.28	24	543763	846	62944389
Nephropathy toxic	11.51	10.28	42	543745	9437	62935798
Ulcer	11.49	10.28	299	543488	25808	62919427
Pruritus	11.47	10.28	2834	540953	358619	62586616
Wound infection pseudomonas	11.46	10.28	31	543756	1297	62943938
Tubulointerstitial nephritis	11.43	10.28	112	543675	19791	62925444
Talipes	11.39	10.28	34	543753	1506	62943729
Hepatitis acute	11.34	10.28	40	543747	9080	62936155
Coronary arterial stent insertion	11.34	10.28	5	543782	2824	62942411
Bronchopulmonary aspergillosis	11.33	10.28	37	543750	8598	62936637
Foetal distress syndrome	11.31	10.28	31	543756	1307	62943928
Stoma site pruritus	11.31	10.28	3	543784	0	62945235
Cardiac monitoring abnormal	11.31	10.28	3	543784	0	62945235
Corneal opacity congenital	11.31	10.28	3	543784	0	62945235
X-ray gastrointestinal tract abnormal	11.31	10.28	3	543784	0	62945235
Renal mass	11.30	10.28	45	543742	2308	62942927
Vascular device infection	11.30	10.28	29	543758	7283	62937952
Oxygen consumption increased	11.25	10.28	10	543777	3874	62941361
Blood pressure decreased	11.22	10.28	449	543338	64573	62880662
Illness	11.20	10.28	327	543460	48732	62896503
White blood cell count decreased	11.20	10.28	1032	542755	138072	62807163
Induced labour	11.18	10.28	25	543762	926	62944309
Injection site bruising	11.14	10.28	452	543335	41458	62903777
Upper respiratory tract inflammation	11.13	10.28	47	543740	2476	62942759
Therapy change	11.13	10.28	22	543765	6059	62939176
Acute graft versus host disease in skin	11.11	10.28	8	543779	3444	62941791
Poor quality sleep	11.10	10.28	113	543674	19822	62925413
Hepatic cirrhosis	11.10	10.28	284	543503	24450	62920785
Full blood count abnormal	11.04	10.28	198	543589	31519	62913716
Dactylitis	11.02	10.28	48	543739	2564	62942671
Cholestasis of pregnancy	10.98	10.28	29	543758	1196	62944039
Soft tissue disorder	10.97	10.28	13	543774	4409	62940826
Haemodynamic instability	10.97	10.28	41	543746	9149	62936086
Nail injury	10.95	10.28	20	543767	639	62944596
Hyperpyrexia	10.95	10.28	9	543778	3623	62941612
Plasma cell myeloma recurrent	10.94	10.28	7	543780	3206	62942029
Femoral hernia incarcerated	10.91	10.28	23	543764	818	62944417
Human anti-human antibody test	10.90	10.28	16	543771	424	62944811
Device malfunction	10.89	10.28	99	543688	17758	62927477
Catheter management	10.88	10.28	6	543781	2981	62942254
Hyperthermia	10.83	10.28	41	543746	9115	62936120
Nasal obstruction	10.76	10.28	36	543751	1695	62943540
Metabolic disorder	10.67	10.28	25	543762	6478	62938757
Amnesia	10.66	10.28	379	543408	55206	62890029
Ear pain	10.60	10.28	232	543555	35886	62909349
Treatment noncompliance	10.60	10.28	241	543546	37084	62908151
Cervical incompetence	10.60	10.28	19	543768	598	62944637
Heat illness	10.59	10.28	11	543776	202	62945033
Lymphopenia	10.58	10.28	103	543684	18224	62927011
Breast cancer metastatic	10.55	10.28	60	543727	11958	62933277
Incoherent	10.53	10.28	14	543773	4516	62940719
Pyelonephritis acute	10.52	10.28	72	543715	4569	62940666
Myocarditis	10.50	10.28	49	543738	10276	62934959
Red blood cell count decreased	10.49	10.28	437	543350	40208	62905027
Cartilage injury	10.47	10.28	39	543748	1938	62943297
Hepatitis B reactivation	10.45	10.28	7	543780	3130	62942105
Dysuria	10.40	10.28	215	543572	33523	62911712
Learning disorder	10.40	10.28	20	543767	665	62944570
Intervertebral disc degeneration	10.39	10.28	191	543596	15541	62929694
Klebsiella infection	10.37	10.28	38	543749	8528	62936707
Pericardial effusion	10.35	10.28	188	543599	29870	62915365
Sleep terror	10.33	10.28	5	543782	2675	62942560
Incorrect route of product administration	10.32	10.28	169	543618	27283	62917952
Abortion threatened	10.32	10.28	18	543769	554	62944681
Rash morbilliform	10.32	10.28	8	543779	3317	62941918
Pain in extremity	10.32	10.28	3084	540703	328402	62616833
Forceps delivery	10.29	10.28	11	543776	209	62945026
Oral pain	10.29	10.28	176	543611	28218	62917017

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Rheumatoid arthritis	480.05	10.27	829	204170	37409	34714523
Drug abuse	437.50	10.27	39	204960	99057	34652875
Toxicity to various agents	386.04	10.27	364	204635	199998	34551934
Completed suicide	310.09	10.27	95	204904	98073	34653859
Foetal exposure during pregnancy	228.46	10.27	612	204387	37489	34714443
Drug interaction	189.09	10.27	685	204314	225261	34526671
Arthralgia	155.07	10.27	1601	203398	168440	34583492
Psoriatic arthropathy	151.35	10.27	349	204650	19449	34732483
Interstitial lung disease	145.70	10.27	762	204237	64520	34687412
Sickle cell anaemia with crisis	133.84	10.27	141	204858	3912	34748020
Dysmorphism	117.28	10.27	117	204882	3039	34748893
Intentional overdose	110.60	10.27	59	204940	43615	34708317
Product use in unapproved indication	99.56	10.27	354	204645	117145	34634787
Overdose	88.51	10.27	258	204741	90801	34661131
Acute kidney injury	88.22	10.27	1259	203740	303729	34448203
Death	83.91	10.27	1740	203259	396309	34355623
Joint swelling	83.18	10.27	619	204380	59271	34692661
Drug reaction with eosinophilia and systemic symptoms	74.61	10.27	51	204948	32961	34718971
Premature baby	74.47	10.27	269	204730	19364	34732568
Enthesopathy	72.78	10.27	111	204888	4502	34747430
Coma	72.41	10.27	97	204902	45581	34706351
C-reactive protein increased	68.91	10.27	548	204451	53550	34698382
Musculoskeletal stiffness	67.98	10.27	488	204511	46192	34705740
Tenosynovitis	67.95	10.27	107	204892	4463	34747469
Drug dependence	66.98	10.27	29	204970	24188	34727744
Synovitis	66.90	10.27	208	204791	13858	34738074
Blood pressure fluctuation	64.99	10.27	307	204692	24942	34726990
Speech disorder developmental	64.70	10.27	72	204927	2128	34749804
Platelet count decreased	62.94	10.27	1019	203980	118698	34633234
Drug resistance	62.79	10.27	37	204962	25890	34726042
Exposure during pregnancy	62.32	10.27	152	204847	8782	34743150
Suicide attempt	62.07	10.27	83	204916	39033	34712899
Suicidal ideation	59.82	10.27	90	204909	40298	34711634
C-reactive protein abnormal	58.44	10.27	146	204853	8564	34743368
Angioedema	56.60	10.27	82	204917	37292	34714640
Psoriasis	56.07	10.27	405	204594	38407	34713525
Foetal anticonvulsant syndrome	55.55	10.27	50	204949	1137	34750795
Drug ineffective	55.11	10.27	2157	202842	454594	34297338
Neonatal respiratory distress syndrome	53.92	10.27	90	204909	3944	34747988
Pneumonia	53.45	10.27	2618	202381	360009	34391923
Maternal exposure during pregnancy	51.95	10.27	99	204900	4819	34747113
Alanine aminotransferase abnormal	51.55	10.27	96	204903	4592	34747340
Psychotic disorder	49.85	10.27	42	204957	24410	34727522
Hypospadias	49.06	10.27	76	204923	3125	34748807
Atrial septal defect	48.64	10.27	123	204876	7269	34744663
Low birth weight baby	48.38	10.27	128	204871	7777	34744155
Hypermagnesaemia	47.00	10.27	25	204974	229	34751703
Nasopharyngitis	45.94	10.27	619	204380	69349	34682583
Off label use	45.50	10.27	2005	202994	417519	34334413
Learning disorder	45.33	10.27	43	204956	1048	34750884
Autism spectrum disorder	44.63	10.27	61	204938	2235	34749697
Cryptorchism	43.94	10.27	57	204942	1984	34749948
Blood pressure systolic increased	43.86	10.27	257	204742	22695	34729237
Lactic acidosis	43.70	10.27	86	204913	34686	34717246
Maternal drugs affecting foetus	43.35	10.27	81	204918	3884	34748048
Arthropathy	42.52	10.27	287	204712	26620	34725312
Intentional product misuse	42.30	10.27	132	204867	45479	34706453
Hepatic function abnormal	41.39	10.27	420	204579	43943	34707989
Arthritis	41.26	10.27	320	204679	31026	34720906
Maternal exposure during breast feeding	41.20	10.27	48	204951	1493	34750439
Hypoglycaemia neonatal	40.78	10.27	53	204946	1848	34750084
Drug withdrawal syndrome	40.51	10.27	34	204965	19800	34732132
Sedation	40.51	10.27	38	204961	20968	34730964
Haemoglobin decreased	40.38	10.27	960	204039	119812	34632120
Poisoning	40.09	10.27	11	204988	12215	34739717
Neutrophil count decreased	39.91	10.27	467	204532	50637	34701295
Pancytopenia	39.02	10.27	779	204220	94378	34657554
Small for dates baby	38.98	10.27	77	204922	3850	34748082
Lung neoplasm malignant	38.73	10.27	203	204796	17192	34734740
Serotonin syndrome	38.51	10.27	36	204963	19897	34732035
Tongue disorder	38.48	10.27	92	204907	5247	34746685
Rheumatoid nodule	38.39	10.27	65	204934	2882	34749050
Pulmonary fibrosis	37.78	10.27	210	204789	18186	34733746
Non-small cell lung cancer	37.60	10.27	76	204923	3864	34748068
Blood pressure systolic abnormal	37.50	10.27	76	204923	3872	34748060
Pain	37.37	10.27	1511	203488	203164	34548768
Rhabdomyolysis	37.36	10.27	240	204759	67923	34684009
Syndactyly	37.23	10.27	35	204964	843	34751089
Pathogen resistance	36.25	10.27	6	204993	9476	34742456
Agitation	35.75	10.27	194	204805	57205	34694727
Urticaria	35.54	10.27	217	204782	62160	34689772
Bradycardia	35.26	10.27	278	204721	75140	34676792
Blood pressure diastolic decreased	34.82	10.27	125	204874	8969	34742963
Ventricular septal defect	34.47	10.27	74	204925	3927	34748005
Renal failure	33.81	10.27	550	204449	130007	34621925
Respiratory arrest	33.01	10.27	72	204927	27971	34723961
Disease progression	32.95	10.27	441	204558	107636	34644296
Infusion related reaction	32.63	10.27	464	204535	52593	34699339
Blood pressure diastolic abnormal	32.57	10.27	81	204918	4737	34747195
Foot deformity	32.51	10.27	78	204921	4459	34747473
Hand deformity	32.21	10.27	69	204930	3656	34748276
Developmental delay	31.99	10.27	58	204941	2717	34749215
Confusional state	31.73	10.27	625	204374	143535	34608397
Joint laxity	31.24	10.27	23	204976	389	34751543
Exposure via breast milk	31.19	10.27	48	204951	1962	34749970
Joint effusion	30.68	10.27	83	204916	5110	34746822
Acute hepatic failure	30.16	10.27	23	204976	14051	34737881
Osteoarthritis	30.15	10.27	216	204783	20426	34731506
Grip strength decreased	30.09	10.27	61	204938	3108	34748824
Talipes	29.95	10.27	46	204953	1877	34750055
Drug ineffective for unapproved indication	29.50	10.27	59	204940	23656	34728276
Cardiac arrest	29.44	10.27	392	204607	95767	34656165
Substance abuse	28.85	10.27	5	204994	7636	34744296
Jaundice neonatal	28.06	10.27	37	204962	1309	34750623
Congenital hand malformation	27.72	10.27	25	204974	570	34751362
Toxic epidermal necrolysis	27.66	10.27	53	204946	21593	34730339
Aggression	27.52	10.27	126	204873	38838	34713094
Serum ferritin increased	27.50	10.27	89	204910	6057	34745875
Plagiocephaly	27.47	10.27	24	204975	524	34751408
Hypermobility syndrome	26.84	10.27	20	204979	345	34751587
Haematocrit decreased	26.77	10.27	298	204701	31918	34720014
Immune reconstitution inflammatory syndrome	26.69	10.27	9	204990	8750	34743182
Intentional self-injury	26.45	10.27	25	204974	13746	34738186
Tendonitis	26.40	10.27	115	204884	9025	34742907
Heart rate decreased	26.08	10.27	293	204706	31452	34720480
Tachycardia	25.43	10.27	347	204652	84425	34667507
Intellectual disability	25.18	10.27	35	204964	1303	34750629
White blood cell count decreased	24.76	10.27	734	204265	94711	34657221
Finger deformity	24.71	10.27	37	204962	1476	34750456
Somnolence	24.66	10.27	481	204518	110635	34641297
Infective pulmonary exacerbation of cystic fibrosis	24.50	10.27	5	204994	6796	34745136
Basal cell carcinoma	24.40	10.27	198	204801	19460	34732472
Polyarthritis	24.30	10.27	70	204929	4470	34747462
Cholestasis	24.27	10.27	79	204920	26869	34725063
Acute chest syndrome	24.21	10.27	27	204972	800	34751132
Cerebral infarction	23.75	10.27	256	204743	27199	34724733
Caesarean section	23.40	10.27	44	204955	2120	34749812
Language disorder	23.32	10.27	45	204954	2211	34749721
Knee arthroplasty	23.31	10.27	96	204903	7348	34744584
Multiple organ dysfunction syndrome	23.11	10.27	313	204686	76253	34675679
Blood lactate dehydrogenase increased	23.06	10.27	221	204778	22769	34729163
Dysgraphia	22.89	10.27	45	204954	2242	34749690
Red blood cell count decreased	22.78	10.27	266	204733	28824	34723108
Astigmatism	22.63	10.27	30	204969	1067	34750865
Depression	22.57	10.27	417	204582	96681	34655251
Liver disorder	22.50	10.27	294	204705	32703	34719229
Metabolic acidosis	22.32	10.27	157	204842	43523	34708409
No adverse event	22.22	10.27	65	204934	22862	34729070
Anal fistula	22.21	10.27	76	204923	5323	34746609
Pneumonia aspiration	22.10	10.27	357	204642	41546	34710386
Diaphragmatic disorder	22.00	10.27	32	204967	1243	34750689
Large for dates baby	21.92	10.27	27	204972	891	34751041
Red blood cell sedimentation rate increased	21.84	10.27	109	204890	9053	34742879
Pain in extremity	21.68	10.27	928	204071	125585	34626347
Foetal growth restriction	21.57	10.27	63	204936	4054	34747878
Hydrops foetalis	21.52	10.27	26	204973	841	34751091
Ultrasound antenatal screen	21.38	10.27	21	204978	535	34751397
Blood pressure increased	21.37	10.27	672	204327	87430	34664502
Hydrocele	20.81	10.27	41	204958	2046	34749886
Hypotonia neonatal	20.70	10.27	32	204967	1313	34750619
Radiation pneumonitis	20.68	10.27	47	204952	2593	34749339
Diabetic ketoacidosis	20.64	10.27	47	204952	17985	34733947
Hyperbilirubinaemia neonatal	20.31	10.27	24	204975	758	34751174
Selective eating disorder	20.29	10.27	37	204962	1741	34750191
Hepatocellular injury	20.08	10.27	65	204934	22146	34729786
Drug intolerance	20.03	10.27	474	204525	59096	34692836
Gastrointestinal infection	19.95	10.27	77	204922	5721	34746211
Knee deformity	19.88	10.27	22	204977	646	34751286
Motor developmental delay	19.88	10.27	22	204977	646	34751286
Product quality issue	19.83	10.27	44	204955	16991	34734941
Irritability	19.82	10.27	76	204923	24614	34727318
Inflammation	19.67	10.27	253	204746	28042	34723890
Dyspraxia	19.65	10.27	18	204981	419	34751513
Lower respiratory tract infection	19.57	10.27	277	204722	31360	34720572
Muscle twitching	19.42	10.27	19	204980	10279	34741653
Cancer pain	19.21	10.27	46	204953	2626	34749306
Hallucination	19.19	10.27	201	204798	51297	34700635
Blood pressure diastolic increased	19.18	10.27	69	204930	4956	34746976
Radiation inflammation	19.05	10.27	25	204974	880	34751052
Trisomy 18	18.94	10.27	23	204976	748	34751184
Electrocardiogram QRS complex prolonged	18.93	10.27	3	204996	4891	34747041
Respiratory depression	18.88	10.27	42	204957	16203	34735729
Drug withdrawal syndrome neonatal	18.60	10.27	55	204944	3564	34748368
Wound	18.60	10.27	150	204849	14714	34737218
Strabismus	18.47	10.27	35	204964	1696	34750236
Unresponsive to stimuli	18.39	10.27	91	204908	27478	34724454
Sexual dysfunction	18.32	10.27	7	204992	6296	34745636
Upper respiratory tract inflammation	18.29	10.27	35	204964	1709	34750223
Body temperature decreased	18.24	10.27	135	204864	12899	34739033
Nasal disorder	18.17	10.27	37	204962	1891	34750041
Myalgia	18.08	10.27	366	204633	83744	34668188
Otitis media	18.08	10.27	47	204952	2825	34749107
Hypotension	18.04	10.27	1090	203909	220559	34531373
Hyperhidrosis	17.92	10.27	324	204675	75368	34676564
Post transplant lymphoproliferative disorder	17.76	10.27	8	204991	6520	34745412
Foetal disorder	17.67	10.27	23	204976	803	34751129
Congenital foot malformation	17.57	10.27	17	204982	425	34751507
Peripheral swelling	17.57	10.27	580	204419	75961	34675971
Dyslexia	17.50	10.27	15	204984	319	34751613
Cleft lip and palate	17.38	10.27	24	204975	888	34751044
Ankylosing spondylitis	17.34	10.27	72	204927	5532	34746400
Disseminated intravascular coagulation	17.31	10.27	200	204799	21616	34730316
Withdrawal syndrome	17.26	10.27	29	204970	12426	34739506
Rash maculo-papular	17.25	10.27	97	204902	28354	34723578
Limb reduction defect	17.17	10.27	14	204985	277	34751655
Neurotoxicity	16.78	10.27	52	204947	17958	34733974
Vitamin D deficiency	16.74	10.27	80	204919	6528	34745404
Adenovirus infection	16.74	10.27	5	204994	5252	34746680
Infection	16.73	10.27	672	204327	90243	34661689
Neuroleptic malignant syndrome	16.55	10.27	52	204947	17882	34734050
Red blood cell sedimentation rate	16.54	10.27	27	204972	1161	34750771
Anal fissure	16.45	10.27	59	204940	4231	34747701
Progressive multifocal leukoencephalopathy	16.23	10.27	20	204979	9744	34742188
Respiratory disorder neonatal	16.23	10.27	32	204967	1598	34750334
Wrong technique in product usage process	16.19	10.27	134	204865	35852	34716080
Localised infection	16.15	10.27	166	204833	17421	34734511
Medical device implantation	15.91	10.27	19	204980	607	34751325
Paranoia	15.90	10.27	29	204970	12039	34739893
Blood parathyroid hormone decreased	15.89	10.27	30	204969	1450	34750482
Multiple congenital abnormalities	15.80	10.27	18	204981	546	34751386
Skin cancer	15.77	10.27	109	204890	10188	34741744
Immunodeficiency	15.74	10.27	69	204930	5429	34746503
Malignant melanoma	15.72	10.27	91	204908	7999	34743933
Tuberculosis	15.71	10.27	95	204904	8482	34743450
Crohn's disease	15.67	10.27	47	204952	3070	34748862
Therapy partial responder	15.66	10.27	20	204979	9596	34742336
Cellulitis	15.62	10.27	414	204585	52537	34699395
Nodule	15.47	10.27	80	204919	6739	34745193
Lacrimal disorder	15.42	10.27	14	204985	322	34751610
Congenital bladder anomaly	15.42	10.27	13	204986	270	34751662
Cleft lip	15.39	10.27	14	204985	323	34751609
Agitation neonatal	15.39	10.27	25	204974	1071	34750861
Cytomegalovirus infection	15.36	10.27	90	204909	26045	34725887
Arthritis bacterial	15.33	10.27	65	204934	5041	34746891
Weight decrease neonatal	15.32	10.27	14	204985	325	34751607
Lip swelling	15.28	10.27	46	204953	16034	34735898
Juvenile idiopathic arthritis	15.11	10.27	34	204965	1863	34750069
Granuloma skin	15.09	10.27	27	204972	1252	34750680
Loss of personal independence in daily activities	15.08	10.27	276	204723	32903	34719029
Pectus excavatum	15.04	10.27	12	204987	230	34751702
Microcephaly	14.94	10.27	21	204978	790	34751142
Inguinal hernia	14.88	10.27	86	204913	7555	34744377
Ankyloglossia congenital	14.87	10.27	13	204986	284	34751648
Obsessive-compulsive disorder	14.86	10.27	7	204992	5557	34746375
Poor venous access	14.81	10.27	65	204934	5118	34746814
Pruritus	14.79	10.27	681	204318	141300	34610632
Coronary artery disease	14.74	10.27	197	204802	48108	34703824
Renal injury	14.67	10.27	27	204972	11168	34740764
Blood albumin decreased	14.38	10.27	132	204867	13440	34738492
Skin injury	14.38	10.27	38	204961	2307	34749625
Renal aplasia	14.36	10.27	20	204979	746	34751186
Iron overload	14.29	10.27	27	204972	1306	34750626
Suspected suicide	14.26	10.27	5	204994	4743	34747189
Lymphangiosis carcinomatosa	14.10	10.27	22	204977	910	34751022
Joint range of motion decreased	14.05	10.27	82	204917	7230	34744702
Agranulocytosis	14.02	10.27	82	204917	23739	34728193
Haemangioma	14.01	10.27	33	204966	1864	34750068
Panniculitis	13.98	10.27	34	204965	1960	34749972
Aspergillus infection	13.98	10.27	32	204967	12222	34739710
Arthritis infective	13.95	10.27	48	204951	3371	34748561
Scoliosis	13.93	10.27	42	204957	2751	34749181
Device leakage	13.76	10.27	11	204988	6564	34745368
Cardiotoxicity	13.76	10.27	8	204991	5640	34746292
Potentiating drug interaction	13.70	10.27	6	204993	4971	34746961
Colon cancer	13.64	10.27	92	204907	8529	34743403
Haemangioma congenital	13.62	10.27	16	204983	502	34751430
Joint ankylosis	13.46	10.27	29	204970	1543	34750389
Congenital anomaly	13.45	10.27	27	204972	1366	34750566
Spinal disorder	13.45	10.27	55	204944	4197	34747735
Oxygen saturation decreased	13.44	10.27	412	204587	53406	34698526
Arthrodesis	13.38	10.27	15	204984	447	34751485
Oropharyngeal pain	13.38	10.27	287	204712	35198	34716734
Abortion spontaneous	13.36	10.27	14	204985	386	34751546
Second primary malignancy	13.27	10.27	16	204983	7870	34744062
Erectile dysfunction	13.26	10.27	69	204930	20568	34731364
Oesophageal fibrosis	13.25	10.27	10	204989	176	34751756
Electrocardiogram QT prolonged	13.24	10.27	165	204834	40787	34711145
Myocardial infarction	13.17	10.27	578	204421	120507	34631425
Spinal compression fracture	13.15	10.27	79	204920	7037	34744895
Vision blurred	13.11	10.27	190	204809	45773	34706159
Akathisia	13.07	10.27	17	204982	8092	34743840
Enteritis infectious	13.05	10.27	26	204973	1308	34750624
Tooth malformation	13.01	10.27	10	204989	181	34751751
Neck mass	12.95	10.27	29	204970	1584	34750348
Vascular insufficiency	12.93	10.27	13	204986	341	34751591
Arnold-Chiari malformation	12.93	10.27	13	204986	341	34751591
Musculoskeletal pain	12.86	10.27	261	204738	31702	34720230
C-reactive protein decreased	12.85	10.27	33	204966	1969	34749963
Hepatic failure	12.77	10.27	135	204864	34396	34717536
Meningeal disorder	12.77	10.27	13	204986	346	34751586
Blood insulin increased	12.74	10.27	13	204986	347	34751585
Decreased appetite	12.70	10.27	1137	203862	165255	34586677
Aspartate aminotransferase increased	12.70	10.27	502	204497	67281	34684651
Joint stiffness	12.68	10.27	108	204891	10765	34741167
Latent tuberculosis	12.66	10.27	26	204973	1337	34750595
Exposure to toxic agent	12.64	10.27	3	204996	3672	34748260
Squamous cell carcinoma of lung	12.59	10.27	32	204967	1897	34750035
Hyperthermia	12.57	10.27	27	204972	10550	34741382
Developmental coordination disorder	12.56	10.27	10	204989	191	34751741
Venoocclusive liver disease	12.53	10.27	17	204982	7949	34743983
Anti-cyclic citrullinated peptide antibody positive	12.47	10.27	31	204968	1812	34750120
Colitis ulcerative	12.46	10.27	150	204849	16370	34735562
Bronchiolitis	12.45	10.27	44	204955	3132	34748800
Pleural fibrosis	12.44	10.27	26	204973	1354	34750578
Maternal exposure before pregnancy	12.43	10.27	19	204980	772	34751160
Fistula discharge	12.41	10.27	20	204979	851	34751081
Synovial cyst	12.41	10.27	36	204963	2308	34749624
Paraesthesia	12.41	10.27	284	204715	63888	34688044
Autoscopy	12.37	10.27	11	204988	246	34751686
Attention deficit hyperactivity disorder	12.31	10.27	38	204961	2521	34749411
Polydactyly	12.30	10.27	24	204975	1189	34750743
Anxiety	12.22	10.27	468	204531	98960	34652972
Anaphylactic shock	12.20	10.27	50	204949	15891	34736041
Nocardiosis	12.15	10.27	4	204995	3947	34747985
Hypertelorism	12.13	10.27	16	204983	566	34751366
Dysstasia	12.12	10.27	117	204882	12078	34739854
Maternal exposure timing unspecified	12.07	10.27	13	204986	370	34751562
Ear disorder	12.05	10.27	29	204970	1661	34750271
Septic arthritis staphylococcal	12.04	10.27	15	204984	501	34751431
Bradycardia neonatal	12.02	10.27	21	204978	955	34750977
Hepatitis E antibody positive	12.01	10.27	11	204988	256	34751676
Weight decreased	12.01	10.27	1195	203804	175106	34576826
Blood test abnormal	12.01	10.27	76	204923	6895	34745037
Bone cyst	12.00	10.27	28	204971	1572	34750360
Adverse drug reaction	11.99	10.27	112	204887	29230	34722702
Nephropathy toxic	11.97	10.27	36	204963	12552	34739380
Foetal heart rate deceleration abnormality	11.92	10.27	15	204984	506	34751426
Pulmonary toxicity	11.85	10.27	69	204930	6078	34745854
Mechanical ileus	11.82	10.27	13	204986	379	34751553
Endophthalmitis	11.80	10.27	3	204996	3505	34748427
Pulmonary vasculitis	11.77	10.27	16	204983	583	34751349
Pleural effusion	11.77	10.27	588	204411	80958	34670974
Post procedural infection	11.74	10.27	58	204941	4798	34747134
Hepatitis	11.69	10.27	87	204912	23817	34728115
Ileus	11.67	10.27	148	204851	16351	34735581
Gross motor delay	11.65	10.27	12	204987	324	34751608
Eosinophilia	11.63	10.27	98	204901	26124	34725808
Drug use disorder	11.62	10.27	5	204994	4186	34747746
Vitamin B complex deficiency	11.55	10.27	13	204986	389	34751543
Malignant neoplasm progression	11.52	10.27	629	204370	87417	34664515
Alanine aminotransferase increased	11.51	10.27	582	204417	80233	34671699
Foetal distress syndrome	11.44	10.27	22	204977	1078	34750854
Extrapyramidal disorder	11.43	10.27	38	204961	12842	34739090
Haematotoxicity	11.43	10.27	19	204980	8175	34743757
Behaviour disorder	11.41	10.27	58	204941	4852	34747080
Umbilical hernia	11.40	10.27	56	204943	4621	34747311
Respiratory rate increased	11.39	10.27	98	204901	9796	34742136
Fracture	11.39	10.27	74	204925	6775	34745157
Bulbospinal muscular atrophy congenital	11.36	10.27	4	204995	11	34751921
Peripheral artery thrombosis	11.31	10.27	35	204964	2325	34749607
Reticulocyte count decreased	11.30	10.27	17	204982	681	34751251
Rheumatoid lung	11.26	10.27	20	204979	922	34751010
Syringe issue	11.21	10.27	10	204989	5654	34746278
Dyspnoea	11.20	10.27	1992	203007	374790	34377142
Back disorder	11.14	10.27	72	204927	6579	34745353
Hernia pain	11.14	10.27	11	204988	282	34751650
Patent ductus arteriosus	11.10	10.27	44	204955	3310	34748622
Muscle spasms	11.07	10.27	345	204654	74656	34677276
Educational problem	11.03	10.27	15	204984	547	34751385
Anal atresia	10.98	10.27	11	204988	287	34751645
Hypertransaminasaemia	10.98	10.27	10	204989	5596	34746336
Hepatitis E virus test positive	10.95	10.27	11	204988	288	34751644
Congestive cardiomyopathy	10.86	10.27	17	204982	7493	34744439
Graft versus host disease in gastrointestinal tract	10.85	10.27	4	204995	3679	34748253
Mydriasis	10.83	10.27	16	204983	7221	34744711
Folate deficiency	10.83	10.27	23	204976	1211	34750721
Small cell lung cancer	10.81	10.27	30	204969	1875	34750057
Spina bifida	10.72	10.27	12	204987	357	34751575
Infected dermal cyst	10.71	10.27	19	204980	875	34751057
Aplasia pure red cell	10.66	10.27	67	204932	6065	34745867
Rebound effect	10.63	10.27	3	204996	3271	34748661
Accidental exposure to product	10.54	10.27	39	204960	12763	34739169
Ear malformation	10.53	10.27	11	204988	302	34751630
Hypermetropia	10.51	10.27	14	204985	500	34751432
Nail pitting	10.47	10.27	11	204988	304	34751628
Gangrene neonatal	10.47	10.27	9	204990	192	34751740
Blood magnesium decreased	10.44	10.27	69	204930	6354	34745578
Palindromic rheumatism	10.44	10.27	9	204990	193	34751739
Pneumonia bacterial	10.40	10.27	111	204888	11761	34740171
Disinhibition	10.39	10.27	3	204996	3223	34748709
Vitamin B12 deficiency	10.36	10.27	49	204950	3982	34747950
Nail bed bleeding	10.36	10.27	12	204987	371	34751561
Abnormal behaviour	10.33	10.27	95	204904	24874	34727058
Forced expiratory volume decreased	10.28	10.27	3	204996	3200	34748732

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Completed suicide	1148.53	9.92	198	577066	245569	78921555
Toxicity to various agents	1132.16	9.92	840	576424	420700	78746424
Rheumatoid arthritis	1080.61	9.92	3643	573621	204827	78962297
Pemphigus	863.64	9.92	2096	575168	97486	79069638
Systemic lupus erythematosus	860.08	9.92	2365	574899	118784	79048340
Arthropathy	844.42	9.92	3011	574253	174100	78993024
Hand deformity	834.55	9.92	2124	575140	101795	79065329
Drug abuse	827.18	9.92	102	577162	162589	79004535
Synovitis	808.96	9.92	2666	574598	148068	79019056
Joint swelling	764.15	9.92	4111	573153	284535	78882589
Glossodynia	747.07	9.92	2031	575233	101306	79065818
Anti-cyclic citrullinated peptide antibody positive	639.21	9.92	1672	575592	81471	79085653
Wound	618.81	9.92	2050	575214	114129	79052995
Infusion related reaction	604.12	9.92	3272	573992	226965	78940159
Maternal exposure during pregnancy	599.74	9.92	2261	575003	134277	79032847
Arthralgia	584.80	9.92	6516	570748	565287	78601837
Pericarditis	571.90	9.92	1858	575406	102378	79064746
Drug interaction	538.94	9.92	1399	575865	413784	78753340
Abdominal discomfort	473.68	9.92	3273	573991	247454	78919670
Discomfort	438.74	9.92	1938	575326	123679	79043445
Alopecia	423.36	9.92	2997	574267	228358	78938766
Intentional overdose	421.10	9.92	122	577142	105838	79061286
Therapeutic product effect decreased	420.92	9.92	2316	574948	161547	79005577
Swelling	418.15	9.92	2844	574420	213867	78953257
Duodenal ulcer perforation	402.41	9.92	1223	576041	64988	79102136
Helicobacter infection	398.15	9.92	1260	576004	68444	79098680
Rheumatoid factor positive	395.76	9.92	1139	576125	58700	79108424
Contraindicated product administered	394.88	9.92	2212	575052	155326	79011798
Pain	387.14	9.92	7195	570069	696607	78470517
Death	375.90	9.92	2480	574784	564034	78603090
Musculoskeletal stiffness	358.18	9.92	2331	574933	172677	78994447
Nasopharyngitis	345.89	9.92	3073	574191	250808	78916316
Hepatic enzyme increased	328.93	9.92	2357	574907	180253	78986871
Drug intolerance	323.09	9.92	3124	574140	260995	78906129
Psoriatic arthropathy	314.04	9.92	1257	576007	76742	79090382
Acute kidney injury	289.10	9.92	2389	574875	517015	78650109
Exposure during pregnancy	268.72	9.92	1443	575821	99689	79067435
Overdose	260.40	9.92	593	576671	183613	78983511
Impaired healing	248.91	9.92	1274	575990	86381	79080743
Suicide attempt	226.30	9.92	162	577102	82770	79084354
Cardiac arrest	225.84	9.92	576	576688	171520	78995604
C-reactive protein abnormal	218.85	9.92	809	576455	47558	79119566
Muscle injury	218.69	9.92	811	576453	47750	79119374
Folliculitis	216.13	9.92	884	576380	54496	79112628
Irritable bowel syndrome	203.51	9.92	942	576322	61299	79105825
Sickle cell anaemia with crisis	199.53	9.92	266	576998	7656	79159468
Treatment failure	199.23	9.92	1998	575266	168488	78998636
Red blood cell sedimentation rate abnormal	195.35	9.92	454	576810	20509	79146615
Drug reaction with eosinophilia and systemic symptoms	195.14	9.92	111	577153	64133	79102991
Sleep disorder due to general medical condition, insomnia type	189.97	9.92	720	576544	42836	79124288
Hypersensitivity	187.63	9.92	2801	574463	259438	78907686
Product use issue	187.30	9.92	2332	574932	207490	78959634
Sedation	186.46	9.92	71	577193	51824	79115300
Lower respiratory tract infection	185.58	9.92	1583	575681	127637	79039487
Blister	184.06	9.92	1487	575777	117989	79049135
Lactic acidosis	181.02	9.92	146	577118	70213	79096911
Knee arthroplasty	177.26	9.92	701	576563	42547	79124577
Bradycardia	176.06	9.92	456	576808	135101	79032023
Sopor	174.45	9.92	18	577246	32992	79134132
Arthritis	172.22	9.92	1421	575843	113459	79053665
Peripheral swelling	169.46	9.92	2818	574446	266799	78900325
Sinusitis	169.00	9.92	2160	575104	193341	78973783
C-reactive protein increased	167.42	9.92	1546	575718	127481	79039643
Hip arthroplasty	159.19	9.92	595	576669	35161	79131963
Blood pressure fluctuation	157.72	9.92	927	576337	66218	79100906
Osteoarthritis	152.47	9.92	1119	576145	86190	79080934
Coma	152.13	9.92	312	576952	100337	79066787
Hypotension	151.42	9.92	2259	575005	438058	78729066
Drug resistance	149.59	9.92	59	577205	42154	79124970
Respiratory arrest	144.85	9.92	122	577142	57428	79109696
Renal failure	144.07	9.92	858	576406	200110	78967014
Rheumatic fever	143.47	9.92	494	576770	28031	79139093
Drug dependence	141.19	9.92	59	577205	40710	79126414
Weight increased	134.53	9.92	2785	574479	274601	78892523
Agitation	134.46	9.92	329	576935	99386	79067738
Stomatitis	129.99	9.92	1629	575635	145128	79021996
Infection	129.32	9.92	2463	574801	239249	78927875
Disease progression	125.42	9.92	800	576464	183562	78983562
Hyperhidrosis	123.83	9.92	619	576645	150873	79016251
Serotonin syndrome	122.77	9.92	88	577176	44939	79122185
Red blood cell sedimentation rate increased	120.93	9.92	654	576610	45288	79121836
Blood pressure systolic abnormal	120.54	9.92	335	576929	16912	79150212
Swollen joint count increased	120.54	9.92	403	576861	22524	79144600
Fibromyalgia	120.08	9.92	838	576426	63502	79103622
Angioedema	119.81	9.92	230	577034	75805	79091319
Blood pressure diastolic abnormal	119.73	9.92	358	576906	18844	79148280
Rhabdomyolysis	118.36	9.92	368	576896	102763	79064361
Blood pressure systolic increased	114.37	9.92	854	576410	66132	79100992
Intentional product misuse	113.93	9.92	333	576931	94832	79072292
Intentional self-injury	112.13	9.92	47	577217	32372	79134752
Neutropenia	111.67	9.92	1440	575824	286270	78880854
Ill-defined disorder	110.87	9.92	837	576427	65038	79102086
Poisoning	110.22	9.92	24	577240	25248	79141876
Device expulsion	109.90	9.92	26	577238	25835	79141289
Product use in unapproved indication	109.01	9.92	1222	576042	249137	78917987
Contusion	108.20	9.92	1594	575670	147182	79019942
Tachycardia	107.74	9.92	798	576466	176970	78990154
Pregnancy	107.44	9.92	432	576832	26419	79140705
Joint effusion	105.90	9.92	329	576935	17685	79149439
Abortion spontaneous	105.00	9.92	458	576806	29049	79138075
Condition aggravated	102.87	9.92	4522	572742	496602	78670522
Depressed level of consciousness	101.88	9.92	358	576906	96294	79070830
Hypermagnesaemia	101.57	9.92	79	577185	1165	79165959
Interstitial lung disease	101.04	9.92	1253	576011	111347	79055777
Metabolic acidosis	100.09	9.92	287	576977	82242	79084882
Multiple organ dysfunction syndrome	98.45	9.92	491	576773	119755	79047369
Grip strength decreased	98.25	9.92	365	576899	21504	79145620
Blood pressure diastolic decreased	93.41	9.92	450	576814	29766	79137358
Drug withdrawal syndrome	93.16	9.92	69	577195	34649	79132475
Somnolence	93.12	9.92	1195	576069	237786	78929338
Syncope	91.26	9.92	844	576420	178605	78988519
Electrocardiogram QT prolonged	91.16	9.92	341	576923	90045	79077079
Cholestasis	90.79	9.92	148	577116	51961	79115163
Constipation	90.12	9.92	1473	575791	281577	78885547
Enthesopathy	86.65	9.92	231	577033	11377	79155747
Inflammation	86.58	9.92	1049	576215	92704	79074420
Myocardial infarction	86.47	9.92	883	576381	183246	78983878
Osteoporosis	86.30	9.92	679	576585	53433	79113691
Anxiety	85.96	9.92	1273	575991	247239	78919885
Hepatocellular injury	85.93	9.92	132	577132	47461	79119663
Rheumatoid nodule	85.09	9.92	299	576965	17139	79149985
Rash	85.05	9.92	5055	572209	573303	78593821
Drug ineffective for unapproved indication	84.25	9.92	151	577113	51087	79116037
Disturbance in attention	84.17	9.92	149	577115	50652	79116472
Disability assessment scale score increased	83.87	9.92	114	577150	3344	79163780
Dyspnoea	83.71	9.92	5218	572046	851807	78315317
Asthenia	80.12	9.92	2963	574301	508726	78658398
Live birth	79.38	9.92	307	576957	18437	79148687
Myalgia	79.25	9.92	910	576354	184731	78982393
Cognitive disorder	78.48	9.92	252	577012	69674	79097450
Foot deformity	78.41	9.92	364	576900	23710	79143414
Cardio-respiratory arrest	78.38	9.92	462	576802	108048	79059076
Febrile neutropenia	77.92	9.92	1189	576075	229810	78937314
Psoriasis	77.41	9.92	990	576274	88597	79078527
Respiratory depression	75.32	9.92	54	577210	27576	79139548
Juvenile idiopathic arthritis	74.38	9.92	128	577136	4635	79162489
Suicidal ideation	73.77	9.92	293	576971	76047	79091077
Pulmonary fibrosis	73.38	9.92	559	576705	43553	79123571
Tremor	73.27	9.92	832	576432	169251	78997873
Vision blurred	72.76	9.92	458	576806	105440	79061684
Bone erosion	72.09	9.92	288	576976	17559	79149565
Tenosynovitis	71.89	9.92	262	577002	15292	79151832
Hepatic failure	71.23	9.92	217	577047	60995	79106129
Psychotic disorder	70.82	9.92	119	577145	41283	79125841
Heart rate decreased	69.00	9.92	796	576468	69520	79097604
Mydriasis	68.82	9.92	21	577243	17622	79149502
Intentional product use issue	68.09	9.92	1510	575754	150602	79016522
Polyarthritis	67.29	9.92	218	577046	11984	79155140
Immune reconstitution inflammatory syndrome	67.16	9.92	10	577254	13831	79153293
Hypoglycaemia	65.45	9.92	448	576816	101146	79065978
Respiratory failure	65.23	9.92	919	576345	179992	78987132
Blood cholesterol increased	65.22	9.92	908	576356	82812	79084312
Joint destruction	65	9.92	137	577127	5788	79161336
Neuropathy peripheral	64.13	9.92	683	576581	140622	79026502
Caesarean section	63.83	9.92	218	577046	12317	79154807
Balance disorder	63.15	9.92	437	576827	98420	79068704
Joint range of motion decreased	62.98	9.92	435	576829	32847	79134277
Acute hepatic failure	61.92	9.92	76	577188	30037	79137087
Gastrointestinal disorder	61.13	9.92	1233	576031	120972	79046152
Unresponsive to stimuli	60.57	9.92	204	577060	55584	79111540
Cytomegalovirus infection	60.43	9.92	137	577127	42507	79124617
Seizure	60.29	9.92	982	576282	187852	78979272
Loss of personal independence in daily activities	60.28	9.92	1061	576203	101519	79065605
Hyponatraemia	59.76	9.92	916	576348	176932	78990192
Musculoskeletal pain	58.49	9.92	1054	576210	101300	79065824
Joint laxity	57.95	9.92	78	577186	2266	79164858
Thrombocytopenia	57.64	9.92	1470	575794	263789	78903335
Nodule	57.61	9.92	323	576941	22671	79144453
Substance abuse	57.58	9.92	5	577259	10521	79156603
Sedation complication	57.02	9.92	21	577243	15648	79151476
Hallucination	56.28	9.92	376	576888	85369	79081755
Injection site erythema	56.10	9.92	836	576428	77361	79089763
Neurotoxicity	56.05	9.92	93	577171	32425	79134699
Gestational diabetes	55.06	9.92	133	577131	6160	79160964
Pain in extremity	54.95	9.92	3194	574070	361344	78805780
Irritability	54.47	9.92	137	577127	41007	79126117
Pathogen resistance	54.29	9.92	18	577246	14324	79152800
Emotional distress	53.76	9.92	132	577132	39837	79127287
Localised infection	53.72	9.92	460	576804	37115	79130009
Femur fracture	53.60	9.92	470	576794	38182	79128942
Injection site pruritus	53.47	9.92	504	576760	41779	79125345
Joint stiffness	53.30	9.92	490	576774	40340	79126784
Suspected suicide	52.82	9.92	7	577257	10569	79156555
Blood pressure diastolic increased	52.72	9.92	227	577037	14315	79152809
No adverse event	52.28	9.92	120	577144	37072	79130052
Hypothermia	51.59	9.92	53	577211	22693	79144431
Ejection fraction decreased	51.54	9.92	108	577156	34469	79132655
Ventricular tachycardia	50.72	9.92	146	577118	41789	79125335
Disorientation	50.41	9.92	258	577006	62518	79104606
Alanine aminotransferase abnormal	50.33	9.92	160	577104	8707	79158417
Diabetic ketoacidosis	49.68	9.92	108	577156	34014	79133110
Red blood cell sedimentation rate	49.11	9.92	118	577146	5447	79161677
Respiratory distress	49.01	9.92	236	577028	58103	79109021
Agranulocytosis	48.65	9.92	165	577099	44865	79122259
Fracture	48.63	9.92	297	576967	21504	79145620
Orthostatic hypotension	48.48	9.92	225	577039	55939	79111185
Flushing	48.44	9.92	407	576857	87861	79079263
Aggression	48.34	9.92	197	577067	50761	79116363
Speech disorder	48.25	9.92	216	577048	54229	79112895
Type 2 diabetes mellitus	47.97	9.92	628	576636	56494	79110630
Coronary artery disease	47.68	9.92	278	576986	65196	79101928
Dizziness	47.67	9.92	3226	574038	523215	78643909
Drug use disorder	47.62	9.92	4	577260	8647	79158477
Cerebrovascular accident	47.46	9.92	814	576450	154478	79012646
Disability	47.29	9.92	247	577017	16873	79150251
Encephalopathy	47.06	9.92	290	576974	67107	79100017
Body temperature decreased	46.74	9.92	395	576869	31750	79135374
Mucormycosis	46.39	9.92	4	577260	8465	79158659
Dysarthria	46.17	9.92	293	576971	67329	79099795
Withdrawal syndrome	46.10	9.92	77	577187	26777	79140347
Basal cell carcinoma	46.02	9.92	443	576821	36932	79130192
Anaphylactic shock	46.01	9.92	122	577142	35874	79131250
Post transplant lymphoproliferative disorder	45.89	9.92	13	577251	11451	79155673
Injection site reaction	45.88	9.92	602	576662	54183	79112941
Creatinine renal clearance decreased	45.74	9.92	42	577222	18960	79148164
Vomiting	44.99	9.92	4179	573085	661649	78505475
Hyperglycaemia	44.88	9.92	311	576953	70024	79097100
Cardiac failure congestive	44.63	9.92	743	576521	141659	79025465
Shock	44.09	9.92	164	577100	43384	79123740
Bronchospasm	43.87	9.92	70	577194	24789	79142335
Infective pulmonary exacerbation of cystic fibrosis	43.85	9.92	19	577245	12832	79154292
Neuroleptic malignant syndrome	43.72	9.92	83	577181	27476	79139648
Posterior reversible encephalopathy syndrome	43.61	9.92	77	577187	26204	79140920
Urticaria	43.58	9.92	1014	576250	184187	78982937
Exposure to toxic agent	43.56	9.92	7	577257	9151	79157973
Muscle twitching	43.45	9.92	70	577194	24694	79142430
Tongue disorder	43.10	9.92	208	577056	13767	79153357
Depression	43.00	9.92	1217	576047	215573	78951551
Fatigue	42.95	9.92	7500	569764	922227	78244897
Neoplasm progression	42.88	9.92	210	577054	51472	79115652
Extrapyramidal disorder	42.79	9.92	61	577203	22618	79144506
Haematotoxicity	42.74	9.92	30	577234	15489	79151635
Chest discomfort	42.69	9.92	722	576542	137322	79029802
Myoclonus	42.41	9.92	85	577179	27575	79139549
Leukopenia	42.29	9.92	591	576673	115922	79051202
Multiple sclerosis relapse	42.21	9.92	183	577081	46350	79120774
Wrong technique in product usage process	42.20	9.92	337	576927	73538	79093586
Blood pressure increased	41.85	9.92	1901	575363	209459	78957665
Abnormal behaviour	41.74	9.92	130	577134	36291	79130833
Coagulopathy	41.64	9.92	128	577136	35878	79131246
Fear	41.62	9.92	59	577205	21927	79145197
Miosis	41.56	9.92	32	577232	15757	79151367
Tendonitis	41.34	9.92	305	576959	23525	79143599
Laryngitis	41.31	9.92	227	577037	15812	79151312
Product quality issue	41.16	9.92	118	577146	33822	79133302
Pancytopenia	41.13	9.92	1527	575737	164218	79002906
Cardiogenic shock	41.04	9.92	160	577104	41754	79125370
Adverse event	40.97	9.92	638	576626	59576	79107548
Latent tuberculosis	40.89	9.92	81	577183	3272	79163852
Psychomotor hyperactivity	40.84	9.92	37	577227	16812	79150312
Venoocclusive liver disease	40.81	9.92	17	577247	11754	79155370
Mental status changes	40.81	9.92	300	576964	66659	79100465
Paradoxical drug reaction	40.46	9.92	3	577261	7182	79159942
Premature labour	40.20	9.92	143	577121	8247	79158877
Eosinophilia	40.12	9.92	180	577084	45165	79121959
Accidental overdose	40.11	9.92	149	577115	39432	79127692
Aspergillus infection	39.78	9.92	48	577216	19113	79148011
Forced expiratory volume decreased	39.44	9.92	5	577259	7809	79159315
Toxic epidermal necrolysis	39.43	9.92	177	577087	44404	79122720
Blood parathyroid hormone decreased	39.38	9.92	166	577098	10370	79156754
Thrombotic microangiopathy	39.30	9.92	53	577211	20116	79147008
Anaphylactic reaction	39.12	9.92	402	576862	83341	79083783
Skin ulcer	38.48	9.92	578	576686	53572	79113552
Nausea	38.25	9.92	6218	571046	950978	78216146
Neck deformity	37.81	9.92	56	577208	1781	79165343
Mobility decreased	37.78	9.92	1155	576109	121020	79046104
Liver disorder	37.66	9.92	735	576529	71682	79095442
Lip swelling	37.66	9.92	160	577104	40751	79126373
Diarrhoea	37.34	9.92	5700	571564	874789	78292335
Tenderness	36.78	9.92	295	576969	23347	79143777
Second primary malignancy	36.62	9.92	30	577234	14320	79152804
Drug level increased	36.54	9.92	155	577109	39496	79127628
Torsade de pointes	36.38	9.92	52	577212	19260	79147864
Off label use	36.37	9.92	5892	571372	901323	78265801
Granuloma skin	36.22	9.92	147	577117	9027	79158097
Acute generalised exanthematous pustulosis	36.06	9.92	43	577221	17211	79149913
Cardiac failure	35.81	9.92	850	576414	153992	79013132
Maternal exposure before pregnancy	35.70	9.92	90	577174	4283	79162841
Acute chest syndrome	35.66	9.92	50	577214	1511	79165613
Synovial cyst	35.63	9.92	156	577108	9909	79157215
Herpes zoster	35.52	9.92	904	576360	92179	79074945
Ischaemic stroke	35.38	9.92	122	577142	33009	79134115
Acute graft versus host disease	34.74	9.92	15	577249	10152	79156972
Feeling abnormal	34.35	9.92	883	576381	158316	79008808
Bradyphrenia	34.34	9.92	17	577247	10623	79156501
Unintentional medical device removal	34.29	9.92	7	577257	7705	79159419
Hepatotoxicity	34.29	9.92	224	577040	51128	79115996
Device difficult to use	34.14	9.92	28	577236	13357	79153767
Transplant rejection	34.05	9.92	55	577209	19382	79147742
Fluid retention	33.90	9.92	332	576932	69477	79097647
Hepatic function abnormal	33.73	9.92	729	576535	72378	79094746
Pulmonary embolism	33.68	9.92	965	576299	170689	78996435
Oropharyngeal pain	33.60	9.92	1033	576231	108320	79058804
Brain oedema	33.53	9.92	84	577180	25179	79141945
Arrhythmia	33.40	9.92	283	576981	60989	79106135
Rash maculo-papular	33.34	9.92	253	577011	55825	79111299
Wheelchair user	33.31	9.92	109	577155	6023	79161101
Hypoxia	33.23	9.92	536	576728	102707	79064417
Injection site swelling	33.07	9.92	502	576762	46630	79120494
Adenovirus infection	33.04	9.92	10	577254	8437	79158687
Joint dislocation	33.00	9.92	223	577041	16716	79150408
Chronic kidney disease	32.80	9.92	313	576951	65841	79101283
Tuberculosis	32.61	9.92	205	577059	14993	79152131
Hyperthermia	32.58	9.92	50	577214	17987	79149137
Facet joint syndrome	32.57	9.92	165	577099	11137	79155987
Lip dry	32.48	9.92	207	577057	15211	79151913
Pancreatitis acute	32.30	9.92	218	577046	49386	79117738
Hemiparesis	32.25	9.92	130	577134	33603	79133521
Aphasia	32.15	9.92	202	577062	46530	79120594
Premature delivery	31.84	9.92	284	576980	23183	79143941
Panniculitis	31.80	9.92	175	577089	12196	79154928
BK virus infection	31.70	9.92	12	577252	8792	79158332
Therapeutic response decreased	31.61	9.92	669	576595	66184	79100940
Bursitis	31.33	9.92	397	576867	35447	79131677
Multiple fractures	31.21	9.92	128	577136	7898	79159226
Status epilepticus	31.15	9.92	86	577178	24955	79142169
Blood glucose increased	30.96	9.92	616	576648	114359	79052765
Haematoma	30.79	9.92	236	577028	51959	79115165
Polyneuropathy	30.75	9.92	82	577182	24069	79143055
Peripheral venous disease	30.73	9.92	209	577055	15700	79151424
Disease recurrence	30.69	9.92	190	577074	43919	79123205
Maternal exposure timing unspecified	30.61	9.92	102	577162	5690	79161434
Acute respiratory distress syndrome	30.56	9.92	190	577074	43877	79123247
Fear of injection	30.50	9.92	121	577143	7353	79159771
Limb deformity	30.48	9.92	75	577189	3515	79163609
Atrial fibrillation	30.40	9.92	1148	576116	196738	78970386
Premature rupture of membranes	30.40	9.92	81	577183	3988	79163136
Tachypnoea	30.38	9.92	124	577140	31939	79135185
Pre-eclampsia	30.37	9.92	116	577148	6925	79160199
Lethargy	30.34	9.92	410	576854	80882	79086242
Product administration error	30.27	9.92	123	577141	31723	79135401
Chest pain	30.20	9.92	1703	575561	280601	78886523
Progressive multifocal leukoencephalopathy	30.15	9.92	65	577199	20535	79146589
Akathisia	29.95	9.92	31	577233	13228	79153896
Restlessness	29.94	9.92	205	577059	46287	79120837
Polyomavirus-associated nephropathy	29.91	9.92	3	577261	5624	79161500
Asthma	29.76	9.92	747	576517	134348	79032776
Red blood cell count decreased	29.65	9.92	583	576681	56930	79110194
Non-small cell lung cancer	29.28	9.92	107	577157	6253	79160871
Neck mass	29.26	9.92	84	577180	4320	79162804
Anhedonia	29.18	9.92	39	577225	14859	79152265
Pulmonary oedema	29.13	9.92	456	576808	87798	79079326
Haematocrit decreased	29.13	9.92	614	576650	60698	79106426
Ankylosing spondylitis	28.97	9.92	169	577095	12036	79155088
Blood creatine phosphokinase increased	28.95	9.92	322	576942	65768	79101356
Sexual dysfunction	28.94	9.92	10	577254	7753	79159371
Malignant mediastinal neoplasm	28.93	9.92	43	577221	1372	79165752
Bronchopulmonary aspergillosis	28.92	9.92	75	577189	22219	79144905
Bone pain	28.82	9.92	261	577003	55481	79111643
Adjustment disorder with depressed mood	28.57	9.92	136	577128	8950	79158174
Electrocardiogram QRS complex prolonged	28.46	9.92	22	577242	10811	79156313
Smear cervix abnormal	28.24	9.92	59	577205	2477	79164647
Haemoglobin decreased	28.23	9.92	1918	575346	220201	78946923
Clostridium difficile colitis	28.05	9.92	129	577135	32154	79134970
Lupus-like syndrome	27.94	9.92	184	577080	13673	79153451
Ulcer	27.94	9.92	336	576928	29636	79137488
Accidental exposure to product	27.91	9.92	124	577140	31198	79135926
Leukocytosis	27.79	9.92	192	577072	43263	79123861
Retinitis	27.74	9.92	97	577167	5546	79161578
Deep vein thrombosis postoperative	27.57	9.92	152	577112	10600	79156524
Drug hypersensitivity	27.45	9.92	1829	575435	297087	78870037
Anti-cyclic citrullinated peptide antibody	27.40	9.92	99	577165	5753	79161371
Vertigo	27.40	9.92	344	576920	68738	79098386
Affective disorder	27.29	9.92	13	577251	8306	79158818
Muscle spasms	27.21	9.92	1012	576252	173718	78993406
Drug tolerance decreased	27.19	9.92	174	577090	12804	79154320
Arthritis infective	26.89	9.92	125	577139	8146	79158978
Hypertransaminasaemia	26.80	9.92	28	577236	11896	79155228
Spinal stenosis	26.76	9.92	201	577063	15590	79151534
Febrile bone marrow aplasia	26.62	9.92	33	577231	12987	79154137
Joint injury	26.52	9.92	345	576919	30990	79136134
Skin exfoliation	26.35	9.92	263	577001	54837	79112287
Rotator cuff repair	26.30	9.92	48	577216	1822	79165302
Dystonia	26.24	9.92	74	577190	21325	79145799
International normalised ratio increased	26.22	9.92	443	576821	84278	79082846
Breast cancer stage I	26.09	9.92	8	577256	6692	79160432
Exostosis	26.03	9.92	210	577054	16648	79150476
Injection site bruising	25.85	9.92	429	576835	40573	79126551
Tenosynovitis stenosans	25.81	9.92	64	577200	3014	79164110
Muscle spasticity	25.80	9.92	75	577189	21400	79145724
Acute myocardial infarction	25.78	9.92	397	576867	76639	79090485
Melaena	25.75	9.92	299	576965	60591	79106533
Haemorrhage intracranial	25.64	9.92	100	577164	26093	79141031
Platelet count decreased	25.64	9.92	1686	575578	192978	78974146
Wound infection	25.54	9.92	276	576988	23715	79143409
Paranoia	25.49	9.92	65	577199	19367	79147757
Therapy partial responder	25.38	9.92	55	577209	17342	79149782
Palpitations	25.28	9.92	710	576554	125900	79041224
Synovial fluid analysis	25.25	9.92	54	577210	2305	79164819
Acute coronary syndrome	25.24	9.92	74	577190	21059	79146065
Coordination abnormal	25.03	9.92	55	577209	17257	79149867
Muscle rigidity	24.94	9.92	68	577196	19814	79147310
Haemorrhage	24.88	9.92	487	576777	90631	79076493
Visual acuity reduced	24.87	9.92	119	577145	29350	79137774
Hyperkalaemia	24.81	9.92	634	576630	113764	79053360
Mania	24.80	9.92	60	577204	18200	79148924
Ear infection	24.64	9.92	368	576896	34064	79133060
Temperature regulation disorder	24.64	9.92	6	577258	5847	79161277
Anuria	24.61	9.92	74	577190	20889	79146235
Haemodynamic instability	24.50	9.92	56	577208	17326	79149798
Rheumatoid lung	24.46	9.92	77	577187	4168	79162956
Endophthalmitis	24.45	9.92	8	577256	6420	79160704
Cardiomyopathy	24.40	9.92	116	577148	28658	79138466
Foot fracture	24.39	9.92	255	577009	21726	79145398
Sinus bradycardia	24.32	9.92	97	577167	25150	79141974
Rash erythematous	24.31	9.92	284	576980	57485	79109639
Respiration abnormal	24.31	9.92	13	577251	7775	79159349
Poor venous access	24.29	9.92	219	577045	17930	79149194
Renal injury	24.29	9.92	54	577210	16873	79150251
Multiple-drug resistance	24.29	9.92	17	577247	8791	79158333
Scleritis	24.18	9.92	78	577186	4278	79162846
Rebound effect	24.16	9.92	11	577253	7215	79159909
Ventricular fibrillation	24.08	9.92	134	577130	31792	79135332
Graft versus host disease	24.06	9.92	45	577219	14981	79152143
Cardiotoxicity	24.01	9.92	32	577232	12207	79154917
Palmar-plantar erythrodysaesthesia syndrome	23.95	9.92	141	577123	32993	79134131
Pancreatitis	23.77	9.92	351	576913	68224	79098900
Asphyxia	23.66	9.92	30	577234	11690	79155434
Injection site pain	23.59	9.92	1158	576106	128680	79038444
Nocardiosis	23.56	9.92	6	577258	5673	79161451
Oral herpes	23.54	9.92	303	576961	27151	79139973
Chills	23.42	9.92	935	576329	159299	79007825
Dislocation of vertebra	23.38	9.92	116	577148	7764	79159360
Respiratory acidosis	23.31	9.92	28	577236	11172	79155952
Loose body in joint	23.17	9.92	37	577227	1258	79165866
Labelled drug-drug interaction medication error	23.14	9.92	112	577152	27538	79139586
Sciatica	22.98	9.92	353	576911	32869	79134255
Prescribed underdose	22.93	9.92	320	576944	29194	79137930
Myelosuppression	22.93	9.92	184	577080	40112	79127012
Venoocclusive disease	22.90	9.92	3	577261	4570	79162554
Injection site rash	22.69	9.92	214	577050	17740	79149384
Nephropathy toxic	22.62	9.92	74	577190	20345	79146779
Dehydration	22.55	9.92	1520	575744	246667	78920457
Immunodeficiency	22.51	9.92	249	577015	21519	79145605
Dyspnoea exertional	22.40	9.92	470	576794	86603	79080521
Pruritus genital	22.33	9.92	3	577261	4483	79162641
Graft versus host disease in gastrointestinal tract	22.33	9.92	9	577255	6347	79160777
Acidosis	22.32	9.92	71	577193	19691	79147433
Angina pectoris	22.28	9.92	253	577011	51479	79115645
Cyanosis	22.25	9.92	100	577164	25082	79142042
Product prescribing error	22.23	9.92	212	577052	44601	79122523
Bradypnoea	22.21	9.92	8	577256	6044	79161080
Skin papilloma	22.20	9.92	93	577171	5793	79161331
Acute graft versus host disease in skin	22.17	9.92	14	577250	7644	79159480
Sleep terror	22.15	9.92	3	577261	4455	79162669
Generalised tonic-clonic seizure	22.09	9.92	207	577057	43703	79123421
Device use error	21.95	9.92	12	577252	7089	79160035
Synovial disorder	21.93	9.92	46	577218	1937	79165187
Potentiating drug interaction	21.82	9.92	19	577245	8800	79158324
Sinus tachycardia	21.71	9.92	167	577097	36741	79130383
Gastroenteritis viral	21.69	9.92	275	576989	24556	79142568
Mental disorder	21.69	9.92	135	577129	31167	79135957
Dysgeusia	21.47	9.92	288	576976	56889	79110235
Tardive dyskinesia	21.40	9.92	27	577237	10544	79156580
Malignant melanoma	21.35	9.92	181	577083	14560	79152564
Pulseless electrical activity	21.30	9.92	44	577220	14116	79153008
Hallucination, visual	21.23	9.92	144	577120	32585	79134539
Hepatic cirrhosis	21.20	9.92	363	576901	34543	79132581
Myopathy	21.10	9.92	77	577187	20486	79146638
Fracture delayed union	21.10	9.92	47	577217	2063	79165061
Klebsiella infection	21.08	9.92	52	577212	15668	79151456
Haemophagocytic lymphohistiocytosis	20.97	9.92	84	577180	21753	79145371
Hydrops foetalis	20.95	9.92	27	577237	751	79166373
Colorectal cancer	20.94	9.92	19	577245	8628	79158496
Skin cancer	20.91	9.92	183	577081	14857	79152267
Pulmonary arterial hypertension	20.89	9.92	120	577144	28246	79138878
Drug eruption	20.88	9.92	440	576824	43495	79123629
Hepatitis cholestatic	20.87	9.92	43	577221	13809	79153315
Diabetes insipidus	20.85	9.92	6	577258	5231	79161893
Drug screen positive	20.63	9.92	9	577255	6054	79161070
Threatened labour	20.60	9.92	24	577240	600	79166524
Paraesthesia	20.46	9.92	1055	576209	175268	78991856
Virologic failure	20.40	9.92	3	577261	4188	79162936
Upper respiratory tract inflammation	20.39	9.92	70	577194	3965	79163159
Product dose omission issue	20.37	9.92	1529	575735	246008	78921116
Drug abuser	20.34	9.92	9	577255	6004	79161120
Cytokine release syndrome	20.19	9.92	165	577099	35833	79131291
Ultrasound antenatal screen	20.17	9.92	25	577239	668	79166456
Obesity	20.16	9.92	362	576902	34763	79132361
Cleft lip and palate	20.03	9.92	25	577239	673	79166451
Compartment syndrome	19.91	9.92	6	577258	5076	79162048
Acute respiratory failure	19.86	9.92	307	576957	59234	79107890
Depressed mood	19.76	9.92	240	577024	48240	79118884
Memory impairment	19.73	9.92	637	576627	111097	79056027
Device leakage	19.70	9.92	30	577234	10826	79156298
Blood calcium decreased	19.66	9.92	142	577122	31677	79135447
Jaundice	19.57	9.92	270	576994	53079	79114045
Personality change	19.54	9.92	27	577237	10143	79156981
Hyperlactacidaemia	19.53	9.92	8	577256	5587	79161537
Pain in jaw	19.37	9.92	227	577037	45924	79121200
Intracranial pressure increased	19.32	9.92	19	577245	8303	79158821
Erectile dysfunction	19.28	9.92	49	577215	14615	79152509
Joint noise	19.27	9.92	68	577196	3906	79163218
Human antichimeric antibody positive	19.24	9.92	39	577225	1602	79165522
Panic attack	19.17	9.92	100	577164	24116	79143008
Nasal polyps	19.10	9.92	15	577249	7312	79159812
Epstein-Barr virus infection	19.08	9.92	48	577216	14368	79152756
Coronary arterial stent insertion	18.99	9.92	10	577254	6034	79161090
Uterine perforation	18.98	9.92	11	577253	6292	79160832
Renal tubular necrosis	18.94	9.92	105	577159	24934	79142190
Dyskinesia	18.88	9.92	220	577044	44553	79122571
Accidental death	18.86	9.92	4	577260	4287	79162837
Blood lactic acid increased	18.83	9.92	40	577224	12704	79154420
Mouth ulceration	18.73	9.92	386	576878	38008	79129116
Finger deformity	18.73	9.92	105	577159	7369	79159755
Cytopenia	18.58	9.92	80	577184	20303	79146821
Bone disorder	18.58	9.92	216	577048	18897	79148227
Antinuclear antibody positive	18.56	9.92	109	577155	7781	79159343
Pseudomonas infection	18.48	9.92	83	577181	20820	79146304
Dry skin	18.39	9.92	364	576900	67631	79099493
Iodine allergy	18.30	9.92	22	577242	569	79166555
Osteomyelitis	18.26	9.92	337	576927	32528	79134596
Cellulitis	18.23	9.92	965	576299	108095	79059029
Transaminases increased	18.22	9.92	264	577000	51479	79115645
Proteinuria	18.22	9.92	149	577115	32353	79134771
Prescribed overdose	18.20	9.92	380	576884	37503	79129621
Foot operation	18.17	9.92	86	577178	5647	79161477
Loss of consciousness	18.15	9.92	1012	576252	166931	79000193
Atrial tachycardia	18.09	9.92	15	577249	7118	79160006
Breast feeding	18.07	9.92	24	577240	688	79166436
Bronchitis	18.01	9.92	1136	576128	129508	79037616
Polyhydramnios	17.98	9.92	39	577225	1681	79165443
Liver injury	17.97	9.92	537	576727	56077	79111047
Multiple allergies	17.95	9.92	30	577234	10430	79156694
Respiratory disorder	17.92	9.92	223	577041	44633	79122491
Hyperbilirubinaemia	17.90	9.92	104	577160	24414	79142710
Influenza	17.87	9.92	1127	576137	128479	79038645
Anger	17.79	9.92	64	577200	17098	79150026
Trisomy 18	17.77	9.92	22	577242	587	79166537
Myocardial ischaemia	17.71	9.92	110	577154	25409	79141715
Toxic skin eruption	17.68	9.92	92	577172	22201	79144923
Nightmare	17.68	9.92	112	577152	25749	79141375
Face oedema	17.65	9.92	125	577139	28011	79139113
Pleuritic pain	17.64	9.92	130	577134	10022	79157102
Autoimmune disorder	17.63	9.92	191	577073	16421	79150703
Ankle arthroplasty	17.59	9.92	36	577228	1489	79165635
Presyncope	17.59	9.92	201	577063	40853	79126271
Deep vein thrombosis	17.57	9.92	706	576558	120213	79046911
Multiple drug therapy	17.53	9.92	4	577260	4074	79163050
Anti-neutrophil cytoplasmic antibody positive vasculitis	17.40	9.92	3	577261	3726	79163398
Oxygen saturation decreased	17.40	9.92	1120	576144	127927	79039197
Dysphagia	17.35	9.92	715	576549	121421	79045703
Cross sensitivity reaction	17.29	9.92	3	577261	3709	79163415
Lung neoplasm malignant	17.23	9.92	290	576974	27502	79139622
Surgery	17.18	9.92	333	576931	32433	79134691
Stevens-Johnson syndrome	17.08	9.92	191	577073	38975	79128149
Device dislocation	16.98	9.92	114	577150	25856	79141268
Metabolic disorder	16.97	9.92	25	577239	9145	79157979
Lung disorder	16.90	9.92	729	576535	79828	79087296
Cancer pain	16.85	9.92	79	577185	5166	79161958
Pulmonary tuberculosis	16.82	9.92	106	577158	7759	79159365
Drug tolerance	16.78	9.92	114	577150	8561	79158563
Personality disorder	16.77	9.92	12	577252	6134	79160990
Pharyngitis	16.75	9.92	241	577023	22134	79144990
Gastrointestinal haemorrhage	16.73	9.92	886	576378	146833	79020291
Anticholinergic syndrome	16.65	9.92	3	577261	3608	79163516
Hemiplegia	16.64	9.92	54	577210	14885	79152239
Postoperative wound infection	16.64	9.92	155	577109	12806	79154318
Hypomania	16.63	9.92	18	577246	7526	79159598
Paralysis	16.58	9.92	45	577219	13132	79153992
Injection site warmth	16.53	9.92	172	577092	14635	79152489
Swollen tongue	16.50	9.92	213	577051	42357	79124767
Body height below normal	16.50	9.92	42	577222	2011	79165113
Hyperpyrexia	16.48	9.92	12	577252	6080	79161044
Inappropriate antidiuretic hormone secretion	16.46	9.92	117	577147	26196	79140928
Cerebral haemorrhage	16.43	9.92	306	576958	57367	79109757
Short stature	16.43	9.92	23	577241	694	79166430
Strongyloidiasis	16.40	9.92	4	577260	3894	79163230
Drug ineffective	16.39	9.92	8333	568931	1072580	78094544
Foetal distress syndrome	16.37	9.92	19	577245	473	79166651
Product administered to patient of inappropriate age	16.29	9.92	10	577254	5543	79161581
Catatonia	16.08	9.92	24	577240	8732	79158392
Skin toxicity	16.05	9.92	22	577242	8292	79158832
Disturbance in social behaviour	15.95	9.92	8	577256	4962	79162162
Rhinorrhoea	15.87	9.92	688	576576	75386	79091738
Ingrown hair	15.85	9.92	23	577241	718	79166406
Neutrophil count decreased	15.83	9.92	832	576432	93127	79073997
Unevaluable event	15.82	9.92	295	576969	55290	79111834
Induced labour	15.72	9.92	25	577239	847	79166277
Mood altered	15.69	9.92	71	577193	17776	79149348
Skin necrosis	15.67	9.92	200	577064	17887	79149237
Cholecystitis chronic	15.57	9.92	30	577234	9876	79157248
Alcohol interaction	15.41	9.92	8	577256	4866	79162258
Defaecation disorder	15.35	9.92	22	577242	679	79166445
Complication of device insertion	15.32	9.92	14	577250	6336	79160788
Hepatitis B reactivation	15.30	9.92	13	577251	6095	79161029
Cushingoid	15.30	9.92	120	577144	9432	79157692
Alcohol abuse	15.26	9.92	10	577254	5353	79161771
Pneumonia aspiration	15.18	9.92	611	576653	66356	79100768
Lymphoedema	15.17	9.92	43	577221	12370	79154754
Laryngospasm	15.16	9.92	5	577259	3992	79163132
Obstructive airways disorder	15.11	9.92	150	577114	31309	79135815
Transplant dysfunction	15.08	9.92	18	577246	7203	79159921
Diplopia	15.07	9.92	162	577102	33304	79133820
Renal impairment	15.05	9.92	962	576302	156821	79010303
Radiation inflammation	15.03	9.92	25	577239	880	79166244
Blood creatinine increased	15.03	9.92	944	576320	154113	79013011
Wound infection pseudomonas	14.98	9.92	35	577229	1586	79165538
Lymphopenia	14.97	9.92	145	577119	30412	79136712
Feeling hot	14.90	9.92	324	576940	59410	79107714
Spinal compression fracture	14.89	9.92	188	577076	16770	79150354
Hepatitis acute	14.79	9.92	60	577204	15482	79151642
Aplasia	14.79	9.92	21	577243	7799	79159325
Sickle cell anaemia	14.77	9.92	21	577243	643	79166481
Bacteraemia	14.74	9.92	159	577105	32665	79134459
Radiation pneumonitis	14.72	9.92	62	577202	3871	79163253
Hypotonia	14.70	9.92	46	577218	12824	79154300
Gestational hypertension	14.64	9.92	38	577226	1841	79165283
Crying	14.64	9.92	102	577162	22941	79144183
Metastases to bone	14.61	9.92	110	577154	24317	79142807
Psychomotor skills impaired	14.59	9.92	10	577254	5227	79161897
Swelling face	14.56	9.92	398	576866	70814	79096310
Post procedural infection	14.54	9.92	136	577128	11248	79155876
Pulmonary haemorrhage	14.52	9.92	56	577208	14661	79152463
Candida infection	14.52	9.92	192	577072	38022	79129102
Placental disorder	14.47	9.92	25	577239	908	79166216
Hallucination, auditory	14.46	9.92	89	577175	20604	79146520
Hyperlipidaemia	14.45	9.92	120	577144	25973	79141151
Lymphatic fistula	14.45	9.92	23	577241	780	79166344
Troponin increased	14.42	9.92	81	577183	19174	79147950
Ataxia	14.40	9.92	114	577150	24925	79142199
Normal newborn	14.32	9.92	94	577170	6978	79160146
Mental impairment	14.30	9.92	80	577184	18956	79148168
Lacrimal disorder	14.24	9.92	18	577246	491	79166633
Clear cell renal cell carcinoma	14.18	9.92	46	577218	2530	79164594
Acute pulmonary oedema	14.14	9.92	54	577210	14176	79152948
Atrioventricular block	14.13	9.92	53	577211	13988	79153136
Troponin T increased	14.09	9.92	4	577260	3518	79163606
Dactylitis	14.08	9.92	48	577216	2709	79164415
Chronic graft versus host disease	14.06	9.92	17	577247	6764	79160360
Confusional state	14.03	9.92	2053	575211	315944	78851180
Onychomycosis	13.91	9.92	105	577159	8156	79158968
Gastroenteritis	13.89	9.92	334	576930	33748	79133376
Coronary artery bypass	13.89	9.92	14	577250	6048	79161076
Oesophageal carcinoma	13.84	9.92	38	577226	11046	79156078
Renal cancer	13.76	9.92	44	577220	12182	79154942
Product preparation error	13.71	9.92	13	577251	5780	79161344
Oliguria	13.68	9.92	66	577198	16243	79150881
Femoral hernia incarcerated	13.64	9.92	23	577241	819	79166305
Sepsis	13.60	9.92	1725	575539	267703	78899421
Anal fissure	13.59	9.92	99	577165	7604	79159520
Mitochondrial toxicity	13.49	9.92	3	577261	3111	79164013
Metastasis	13.49	9.92	18	577246	6862	79160262
Abortion threatened	13.46	9.92	16	577248	409	79166715
Hypokalaemia	13.43	9.92	880	576384	143160	79023964
Vascular purpura	13.39	9.92	3	577261	3095	79164029
Cytomegalovirus chorioretinitis	13.37	9.92	12	577252	5478	79161646
Clavicle fracture	13.36	9.92	65	577199	4316	79162808
Endodontic procedure	13.35	9.92	47	577217	2696	79164428
Spinal osteoarthritis	13.34	9.92	184	577080	16743	79150381
Catheter site erythema	13.32	9.92	11	577253	5229	79161895
Rash morbilliform	13.20	9.92	15	577249	6135	79160989
Acute lymphocytic leukaemia recurrent	13.18	9.92	9	577255	4715	79162409
Colon cancer	13.18	9.92	162	577102	14361	79152763
Abortion incomplete	13.18	9.92	3	577261	3061	79164063
Bronchopulmonary aspergillosis allergic	13.16	9.92	3	577261	3058	79164066
Left ventricular dysfunction	13.16	9.92	84	577180	19277	79147847
Visual impairment	13.15	9.92	539	576725	91592	79075532
Reversible cerebral vasoconstriction syndrome	13.14	9.92	3	577261	3054	79164070
Knee operation	13.14	9.92	80	577184	5786	79161338
Hypoventilation	13.07	9.92	20	577244	7204	79159920
Cell death	13.05	9.92	9	577255	4690	79162434
Stillbirth	13.02	9.92	60	577204	3895	79163229
Ileus	12.94	9.92	264	577000	25947	79141177
Antibody test positive	12.88	9.92	47	577217	2745	79164379
Congestive cardiomyopathy	12.84	9.92	43	577221	11737	79155387
Joint warmth	12.82	9.92	33	577231	1591	79165533
Sensitisation	12.81	9.92	4	577260	3307	79163817
Type I hypersensitivity	12.79	9.92	8	577256	4390	79162734
Extra dose administered	12.78	9.92	26	577238	8389	79158735
Pyelonephritis acute	12.77	9.92	81	577183	5942	79161182
Human herpesvirus 6 infection	12.77	9.92	12	577252	5358	79161766
Incorrect route of product administration	12.73	9.92	177	577087	34752	79132372
Wrong product administered	12.73	9.92	29	577235	8983	79158141
Motor dysfunction	12.72	9.92	59	577205	14674	79152450
Nail injury	12.72	9.92	19	577245	609	79166515
Hypertensive crisis	12.68	9.92	93	577171	20677	79146447
Bladder cancer	12.62	9.92	86	577178	19440	79147684
Drug dose omission by device	12.61	9.92	16	577248	6234	79160890
Haematemesis	12.61	9.92	285	576979	51979	79115145
Bronchial secretion retention	12.59	9.92	7	577257	4097	79163027
Bone density increased	12.58	9.92	22	577242	807	79166317
Lymph gland infection	12.57	9.92	18	577246	555	79166569
Haemorrhage in pregnancy	12.50	9.92	30	577234	1384	79165740
Heat illness	12.47	9.92	18	577246	559	79166565
Polyuria	12.46	9.92	61	577203	14953	79152171
Gamma-glutamyltransferase increased	12.40	9.92	301	576963	54379	79112745
Glycosylated haemoglobin increased	12.36	9.92	85	577179	19175	79147949
Placental insufficiency	12.36	9.92	26	577238	1097	79166027
Musculoskeletal disorder	12.29	9.92	221	577043	21227	79145897
Osteoporotic fracture	12.29	9.92	62	577202	4178	79162946
Toothache	12.24	9.92	208	577056	19762	79147362
Diaphragmatic disorder	12.24	9.92	34	577230	1716	79165408
Cervical incompetence	12.22	9.92	17	577247	510	79166614
Throat tightness	12.21	9.92	136	577128	27771	79139353
Tuberculin test positive	12.20	9.92	53	577211	3355	79163769
Lower limb fracture	12.19	9.92	236	577028	22979	79144145
Cryptococcosis	12.18	9.92	5	577259	3488	79163636
Dermatitis atopic	12.17	9.92	35	577229	10021	79157103
Complications of transplanted kidney	12.13	9.92	17	577247	6349	79160775
Stoma site pruritus	12.12	9.92	4	577260	6	79167118
Kidney infection	12.12	9.92	224	577040	21627	79145497
Infusion site pain	12.11	9.92	57	577207	14119	79153005
Joint ankylosis	12.07	9.92	39	577225	2141	79164983
Oligoarthritis	12.03	9.92	20	577244	704	79166420
Blood folate increased	12.00	9.92	17	577247	519	79166605
Oxygen consumption increased	11.99	9.92	11	577253	4968	79162156
Lower respiratory tract congestion	11.97	9.92	59	577205	3938	79163186
Haemoptysis	11.96	9.92	311	576953	55688	79111436
Prostatic specific antigen increased	11.95	9.92	37	577227	10349	79156775
Drug specific antibody	11.92	9.92	44	577220	2584	79164540
Intraocular pressure increased	11.91	9.92	31	577233	9174	79157950
Tooth disorder	11.91	9.92	261	577003	25972	79141152
Brain injury	11.90	9.92	43	577221	11474	79155650
Osteonecrosis	11.90	9.92	156	577108	30939	79136185
Palmoplantar keratoderma	11.90	9.92	6	577258	3710	79163414
Human anti-human antibody test	11.90	9.92	15	577249	408	79166716
Iron overload	11.85	9.92	35	577229	1829	79165295
C-reactive protein	11.85	9.92	69	577195	4910	79162214
Psychiatric decompensation	11.81	9.92	7	577257	3956	79163168
End stage renal disease	11.74	9.92	47	577217	12173	79154951
Neutrophilia	11.71	9.92	25	577239	7926	79159198
Cystitis	11.70	9.92	480	576784	52252	79114872
Hyperprolactinaemia	11.66	9.92	10	577254	4666	79162458
Lung adenocarcinoma	11.62	9.92	97	577167	7767	79159357
Capillary leak syndrome	11.61	9.92	7	577257	3918	79163206
Hepatic cytolysis	11.61	9.92	133	577131	27018	79140106
Fulminant type 1 diabetes mellitus	11.57	9.92	30	577234	1453	79165671
Cytomegalovirus infection reactivation	11.55	9.92	29	577235	8687	79158437
C-reactive protein decreased	11.54	9.92	44	577220	2624	79164500
Device issue	11.51	9.92	133	577131	26975	79140149
Post-traumatic stress disorder	11.50	9.92	11	577253	4870	79162254
Arthritis bacterial	11.46	9.92	109	577155	9057	79158067
Glomerular filtration rate decreased	11.43	9.92	107	577157	22595	79144529
Joint lock	11.43	9.92	50	577214	3175	79163949
Oesophageal fibrosis	11.40	9.92	10	577254	176	79166948
Stress cardiomyopathy	11.34	9.92	42	577222	11124	79156000
Maternal exposure during breast feeding	11.29	9.92	45	577219	2740	79164384
Serum ferritin increased	11.29	9.92	115	577149	9732	79157392
Hypertonia	11.28	9.92	22	577242	7210	79159914
Bone density abnormal	11.27	9.92	48	577216	3012	79164112
Hypoxic-ischaemic encephalopathy	11.18	9.92	25	577239	7795	79159329
Foetal exposure during pregnancy	11.14	9.92	76	577188	5714	79161410
Tumour lysis syndrome	11.14	9.92	115	577149	23824	79143300
Bulbospinal muscular atrophy congenital	11.09	9.92	4	577260	9	79167115
Ascites	11.01	9.92	441	576823	75121	79092003
General physical health deterioration	11.00	9.92	2205	575059	273033	78894091
Anal fistula	10.99	9.92	87	577177	6857	79160267
Toxic encephalopathy	10.99	9.92	44	577220	11396	79155728
Plasma cell myeloma recurrent	10.95	9.92	12	577252	4989	79162135
Lip oedema	10.94	9.92	18	577246	6298	79160826
Spondylitis	10.90	9.92	65	577199	4666	79162458
Colitis ulcerative	10.88	9.92	329	576935	34413	79132711
Hypercapnia	10.88	9.92	31	577233	8904	79158220
Myofascial pain syndrome	10.88	9.92	36	577228	2001	79165123
Cardiac disorder	10.87	9.92	378	576886	65379	79101745
Temperature intolerance	10.87	9.92	35	577229	9670	79157454
Cerebral haematoma	10.86	9.92	26	577238	7916	79159208
Silent thyroiditis	10.82	9.92	10	577254	189	79166935
Graft versus host disease in skin	10.81	9.92	17	577247	6056	79161068
Heparin-induced thrombocytopenia	10.79	9.92	35	577229	9647	79157477
Dissociation	10.78	9.92	8	577256	4013	79163111
Shock haemorrhagic	10.77	9.92	93	577171	19967	79147157
Renal tubular disorder	10.76	9.92	19	577245	6467	79160657
Paresis	10.76	9.92	9	577255	4252	79162872
Sputum discoloured	10.72	9.92	103	577161	21640	79145484
Dyspnoea at rest	10.72	9.92	23	577241	7279	79159845
Ventricular hypokinesia	10.72	9.92	33	577231	9246	79157878
Circulatory collapse	10.69	9.92	200	577064	37468	79129656
Ischaemic cardiomyopathy	10.68	9.92	25	577239	7670	79159454
Incoherent	10.66	9.92	25	577239	7667	79159457
Pulmonary pain	10.66	9.92	62	577202	4411	79162713
Injection site extravasation	10.65	9.92	112	577152	9557	79157567
Benign ovarian tumour	10.64	9.92	13	577251	342	79166782
Rales	10.62	9.92	93	577171	19908	79147216
Thinking abnormal	10.62	9.92	54	577210	13107	79154017
Colitis microscopic	10.61	9.92	41	577223	10727	79156397
Lymphangiosis carcinomatosa	10.57	9.92	37	577227	2117	79165007
Hypercholesterolaemia	10.55	9.92	230	577034	22865	79144259
Platelet count increased	10.52	9.92	224	577040	22182	79144942
Seronegative arthritis	10.51	9.92	64	577200	4628	79162496
Ketoacidosis	10.51	9.92	26	577238	7828	79159296
Immune-mediated myositis	10.51	9.92	6	577258	3461	79163663
Small for dates baby	10.51	9.92	15	577249	461	79166663
Metastases to liver	10.49	9.92	143	577121	28171	79138953
Anal skin tags	10.49	9.92	15	577249	462	79166662
Jaundice cholestatic	10.46	9.92	44	577220	11240	79155884
Frequent bowel movements	10.43	9.92	284	576980	29255	79137869
Immunosuppression	10.43	9.92	140	577124	12663	79154461
Eye swelling	10.42	9.92	132	577132	26336	79140788
Hepatic siderosis	10.42	9.92	9	577255	155	79166969
Neurologic neglect syndrome	10.40	9.92	4	577260	2903	79164221
Device related infection	10.39	9.92	180	577084	34114	79133010
Acute myeloid leukaemia	10.38	9.92	159	577105	30726	79136398
Delivery	10.38	9.92	19	577245	723	79166401
Complication associated with device	10.37	9.92	79	577185	17417	79149707
Pulmonary congestion	10.35	9.92	136	577128	26964	79140160
Folate deficiency	10.35	9.92	50	577214	3310	79163814
Cardiopulmonary failure	10.34	9.92	21	577243	6780	79160344
Cyst	10.33	9.92	149	577115	13691	79153433
Partial seizures	10.32	9.92	32	577232	8946	79158178
Disinhibition	10.30	9.92	3	577261	2595	79164529
Blindness	10.28	9.92	144	577120	28239	79138885
Tubulointerstitial nephritis	10.24	9.92	205	577059	38030	79129094
Mixed liver injury	10.21	9.92	25	577239	7553	79159571
Hyperthyroidism	10.21	9.92	107	577157	22102	79145022
Catheter management	10.19	9.92	7	577257	3656	79163468
Pelvic pain	10.18	9.92	56	577208	13325	79153799
Pulmonary function test abnormal	10.16	9.92	9	577255	4135	79162989
Twin pregnancy	10.16	9.92	21	577243	875	79166249
Upper respiratory tract infection	10.16	9.92	779	576485	90389	79076735
Polydactyly	10.13	9.92	7	577257	85	79167039
Respiratory tract infection viral	10.12	9.92	59	577205	4200	79162924
Diastolic dysfunction	10.12	9.92	42	577222	10769	79156355
Ligament rupture	10.10	9.92	50	577214	3344	79163780
Abortion missed	10.05	9.92	26	577238	1257	79165867
Hepatitis E antibody positive	10.03	9.92	11	577253	257	79166867
Aphthous ulcer	10.02	9.92	175	577089	16714	79150410
Skin ulcer haemorrhage	10.02	9.92	16	577248	544	79166580
Vacuum extractor delivery	10.01	9.92	8	577256	123	79167001
Mucosal inflammation	9.99	9.92	446	576818	75134	79091990
Livedo reticularis	9.96	9.92	9	577255	4094	79163030
Sleep apnoea syndrome	9.95	9.92	195	577069	36283	79130841
Acute lung injury	9.93	9.92	5	577259	3095	79164029
Diabetes mellitus inadequate control	9.93	9.92	120	577144	24144	79142980
Nervousness	9.93	9.92	176	577088	33239	79133885

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A02AA02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS ANTACIDS Magnesium compounds
ATC	A06AD02	ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Osmotically acting laxatives
ATC	A12CC10	ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Magnesium
MeSH PA	D000863	Antacids
MeSH PA	D005765	Gastrointestinal Agents
CHEBI has role	CHEBI:33287	fertilizers
CHEBI has role	CHEBI:65265	antacids

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypocalcemia	indication	5291005
Constipation	indication	14760008	DOID:2089
Osteoporosis	indication	64859006	DOID:11476
Postmenopausal osteoporosis	indication	102447009
Indigestion	indication	162031009
Hypomagnesemia	indication	190855004
Incomplete passage of stool	indication	249515001
Peptic ulcer	contraindication	13200003	DOID:750
Bipolar disorder	contraindication	13746004	DOID:3312
Hyperkalemia	contraindication	14140009
Hypocupremia	contraindication	19577007
Hyperphosphatemia	contraindication	20165001	DOID:0050459
Hypervitaminosis D	contraindication	27712000	DOID:9971
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
Conduction disorder of the heart	contraindication	44808001
Low blood pressure	contraindication	45007003
Chronic heart failure	contraindication	48447003
Metabolic acidosis	contraindication	59455009
Diarrhea	contraindication	62315008
Blood coagulation disorder	contraindication	64779008	DOID:1247
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Hypercalciuria	contraindication	71938000
Gastrointestinal hemorrhage	contraindication	74474003
Phototoxicity	contraindication	84326006
Kidney disease	contraindication	90708001	DOID:557
Kidney stone	contraindication	95570007
Neoplasm of endometrium	contraindication	123844007	DOID:1380
Gastrointestinal obstruction	contraindication	126765001
Seizure disorder	contraindication	128613002
Impaired renal function disorder	contraindication	197663003
Osteolysis	contraindication	203522001
Hypomania	contraindication	231496004
Gastroparesis	contraindication	235675006
Disease of liver	contraindication	235856003	DOID:409
Rhabdomyolysis	contraindication	240131006
Endometrial carcinoma	contraindication	254878006	DOID:2871
Esophageal dysmotility	contraindication	266434009	DOID:9192
Arteriosclerosis obliterans	contraindication	361133006	DOID:5160
Primary adrenocortical insufficiency	contraindication	373662000
Ketoacidosis in diabetes mellitus	contraindication	420422005	DOID:1837
Carcinoma of female breast	contraindication	447782002
Genitourinary Tract Infections	contraindication
Vitamin K Deficiency Induced Hypoprothrombinemia	contraindication
Esophageal Compression	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strength	Trade name	Applicant	Application number	Approval date	Type	Dose form	Route	Patent number	Patent expiration date	Patent use
12GM/BOT;3.5GM/BOT;10MG/BOT	CLENPIQ	FERRING PHARMS INC	N209589	Nov. 28, 2017	RX	SOLUTION	ORAL	11191753	June 23, 2034	FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY
12GM/BOT;3.5GM/BOT;10MG/BOT	CLENPIQ	FERRING PHARMS INC	N209589	Nov. 28, 2017	RX	SOLUTION	ORAL	9827231	June 26, 2034	FOR CLEANSING THE LARGE INTESTINE AS A PREPARATION FOR COLONOSCOPY

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4020248	VUID
N0000148146	NUI
D01167	KEGG_DRUG
4017641	VANDF
4017717	VANDF
4020248	VANDF
C0024477	UMLSCUI
CHEBI:31794	CHEBI
CHEMBL1200572	ChEMBL_ID
D008277	MESH_DESCRIPTOR_UI
DB01377	DRUGBANK_ID
3A3U0GI71G	UNII
6850729	PUBCHEM_CID
6582	RXNORM
40492	MMSL
42624	MMSL
5015	MMSL
5585	MMSL
d03797	MMSL
000788	NDDF
002435	NDDF
419521006	SNOMEDCT_US
66389008	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Calcemin Advance	HUMAN OTC DRUG LABEL	5	0280-0272	TABLET, FILM COATED	40 mg	ORAL	Export only	2 sections
Calcemin Silver	HUMAN OTC DRUG LABEL	3	0280-0273	TABLET, FILM COATED	40 mg	ORAL	Export only	2 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	0603-0209	TABLET	400 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	0603-0213	TABLET	253 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	0603-0213	TABLET	253 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
Vitafol Ultra	HUMAN PRESCRIPTION DRUG LABEL	17	0642-0093	CAPSULE, LIQUID FILLED	20 mg	ORAL	UNAPPROVED DRUG OTHER	13 sections
Vitafol Ultra	HUMAN PRESCRIPTION DRUG LABEL	17	0642-0093	CAPSULE, LIQUID FILLED	20 mg	ORAL	UNAPPROVED DRUG OTHER	13 sections
Select OB	HUMAN PRESCRIPTION DRUG LABEL	15	0642-0120	TABLET, CHEWABLE	25 mg	ORAL	UNAPPROVED DRUG OTHER	13 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Strovite One Caplets	HUMAN PRESCRIPTION DRUG LABEL	20	0642-0207	TABLET	50 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Vitafol Fe Plus	HUMAN PRESCRIPTION DRUG LABEL	17	0642-7473	CAPSULE, LIQUID FILLED	20 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Vitafol Fe Plus	HUMAN PRESCRIPTION DRUG LABEL	17	0642-7473	CAPSULE, LIQUID FILLED	20 mg	ORAL	UNAPPROVED DRUG OTHER	14 sections
Marnatal F	HUMAN PRESCRIPTION DRUG LABEL	13	0682-1570	CAPSULE	25 mg	ORAL	UNAPPROVED DRUG OTHER	4 sections
BACMIN	HUMAN PRESCRIPTION DRUG LABEL	19	0682-3001	TABLET, COATED	50 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	10135-583	TABLET	400 mg	ORAL	OTC MONOGRAPH FINAL	12 sections
magnesium oxide	HUMAN OTC DRUG LABEL	1	10135-721	TABLET	420 mg	ORAL	OTC monograph final	9 sections
Quflora Pediatric Drops	HUMAN PRESCRIPTION DRUG LABEL	13	15370-100	LIQUID	10 mg	ORAL	UNAPPROVED DRUG OTHER	11 sections
Quflora Pediatric Drops	HUMAN PRESCRIPTION DRUG LABEL	13	15370-101	LIQUID	12 mg	ORAL	UNAPPROVED DRUG OTHER	11 sections
Quflora Pediatric	HUMAN PRESCRIPTION DRUG LABEL	14	15370-103	TABLET, CHEWABLE	15 mg	ORAL	UNAPPROVED DRUG OTHER	12 sections
Quflora Pediatric	HUMAN PRESCRIPTION DRUG LABEL	14	15370-104	TABLET, CHEWABLE	15 mg	ORAL	UNAPPROVED DRUG OTHER	12 sections
Quflora Pediatric	HUMAN PRESCRIPTION DRUG LABEL	14	15370-105	TABLET, CHEWABLE	15 mg	ORAL	UNAPPROVED DRUG OTHER	12 sections
TriStart DHA	HUMAN PRESCRIPTION DRUG LABEL	15	15370-250	CAPSULE, LIQUID FILLED	30 mg	ORAL	UNAPPROVED DRUG OTHER	12 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	24689-132	TABLET	400 mg	ORAL	OTC monograph final	11 sections
SODIUM PICOSULFATE, MAGNESIUM OXIDE AND ANHYDROUS CITRIC ACID	HUMAN PRESCRIPTION DRUG LABEL	3	31722-874	POWDER, METERED	3.50 g	ORAL	ANDA	25 sections
PNV-Select	HUMAN PRESCRIPTION DRUG LABEL	18	42192-320	TABLET, FILM COATED	30 ug	ORAL	unapproved drug other	10 sections
PNV-Omega	HUMAN PRESCRIPTION DRUG LABEL	13	42192-332	CAPSULE, GELATIN COATED	45 mg	ORAL	unapproved drug other	12 sections
MigralexDr. Mauskop	HUMAN OTC DRUG LABEL	2	49886-001	TABLET, COATED	75 mg	ORAL	OTC monograph not final	26 sections
Nestabs ONE	HUMAN PRESCRIPTION DRUG LABEL	10	50967-410	CAPSULE, GELATIN COATED	15 mg	ORAL	unapproved drug other	12 sections
Nestabs ONE	HUMAN PRESCRIPTION DRUG LABEL	10	50967-410	CAPSULE, GELATIN COATED	15 mg	ORAL	unapproved drug other	12 sections
Magnesium Oxide	HUMAN OTC DRUG LABEL	1	53808-0684	TABLET	400 mg	ORAL	OTC MONOGRAPH FINAL	13 sections