tirilazad 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4063 110101-66-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tirilazad mesylate
  • tirilazad
  • tirilazad mesilate
  • freedox
a lazaroid; potent inhibitor of iron-dependent lipid peroxidation; has shown excellent activity in in vivo models of experimental central nervous system trauma & ischemia; structure given in first source; tradename Freedox
  • Molecular weight: 624.87
  • Formula: C38H52N6O2
  • CLOGP: 7.70
  • LIPINSKI: 2
  • HAC: 8
  • HDO: 0
  • TPSA: 72.88
  • ALOGS: -3.91
  • ROTB: 6

Drug dosage:

DoseUnitRoute
0.42 g P

ADMET properties:

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

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