laquinimod 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
immunomodulators, both stimulant/suppressive and stimulant 4825 248282-07-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nerventra
  • laquinimod
  • laquinimod sodium
  • ABR-215062 sodium
  • TV-5600
Laquinimod is an immunomodulator developed by Teva for oral treatment for multiple sclerosis.
  • Molecular weight: 356.81
  • Formula: C19H17ClN2O3
  • CLOGP: 3.07
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 60.85
  • ALOGS: -3.91
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 5, 2013 Ministry of Health of the Russian Federation Teva

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N07XX10 NERVOUS SYSTEM
OTHER NERVOUS SYSTEM DRUGS
OTHER NERVOUS SYSTEM DRUGS
Other nervous system drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Relapsing remitting multiple sclerosis indication 426373005 DOID:2378




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.66 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D08938 KEGG_DRUG
248281-84-7 SECONDARY_CAS_RN
CHEBI:134738 CHEBI
CHEMBL66092 ChEMBL_ID
CHEMBL2103814 ChEMBL_ID
C476223 MESH_SUPPLEMENTAL_RECORD_UI
7639 IUPHAR_LIGAND_ID
DB06685 DRUGBANK_ID
C1260208 UMLSCUI
8089 INN_ID
54677946 PUBCHEM_CID
908SY76S4G UNII

Pharmaceutical products:

None