reposal 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
hypnotics, barbituric acid derivatives 3824 3625-25-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • reposal
  • reposamal
  • Molecular weight: 262.31
  • Formula: C14H18N2O3
  • CLOGP: 2.71
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 75.27
  • ALOGS: -3.16
  • ROTB: 2

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,BRAF,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,MAPK7,PDK1,PDK2,PRKDC,TEK 14
kinase-selectivity-class GRK2,PDK1 2
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05CA12 NERVOUS SYSTEM
PSYCHOLEPTICS
HYPNOTICS AND SEDATIVES
Barbiturates, plain

Related Drugs by ATC class:

N05CA Barbiturates, plain 17 drugs
allobarbitalamobarbitalaprobarbitalbarbitalbutobarbitalcyclobarbitaletallobarbitalheptabarbhexobarbitalmethohexitalpentobarbitalproxibarbal show all 17 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.62 acidic
pKa2 9.32 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C3652551 UMLSCUI
CHEBI:135079 CHEBI
CHEMBL505851 ChEMBL_ID
DB13805 DRUGBANK_ID
19254 PUBCHEM_CID
3T5TIX1AYI UNII
3T5TIX1AYI INXIGHT DRUGS

Pharmaceutical products:

None