ranimustine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antineoplastic, alkylating agents, (beta-chloroethyl)amine derivatives 3519 58994-96-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ranimustine
  • cymerin
  • cymerine
  • Molecular weight: 327.72
  • Formula: C10H18ClN3O7
  • CLOGP: -0.16
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 4
  • TPSA: 140.92
  • ALOGS: -1.32
  • ROTB: 6

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Ventricular hypokinesia 73.40 72.02 15 349 9264 79734760

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01AD07 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
ALKYLATING AGENTS
Nitrosoureas
MeSH PA D000970 Antineoplastic Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.95 acidic
pKa2 13.56 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01760 KEGG_DRUG
C0243666 UMLSCUI
CHEBI:32089 CHEBI
CHEMBL2105348 ChEMBL_ID
DB13832 DRUGBANK_ID
C020766 MESH_SUPPLEMENTAL_RECORD_UI
71741 PUBCHEM_CID
5900 INN_ID
RYH2T97J77 UNII
010958 NDDF

Pharmaceutical products:

None