edoxudine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
uridine derivatives used as antiviral agents and as antineoplastics 3173 15176-29-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • edoxudine
  • epoxudine
  • Molecular weight: 256.26
  • Formula: C11H16N2O5
  • CLOGP: -0.86
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 99.10
  • ALOGS: -0.62
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D06BB09 DERMATOLOGICALS
ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
CHEMOTHERAPEUTICS FOR TOPICAL USE
Antivirals

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.34 acidic
pKa2 13.02 acidic
pKa3 13.7 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Thymidine kinase Kinase IC50 6.82 CHEMBL

External reference:

IDSource
D03956 KEGG_DRUG
C0115510 UMLSCUI
CHEBI:135051 CHEBI
CHEMBL318153 ChEMBL_ID
DB13421 DRUGBANK_ID
66377 PUBCHEM_CID
5512 INN_ID
15ZQM81Y3R UNII
49428 RXNORM
005116 NDDF

Pharmaceutical products:

None