docosanol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
940 661-19-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • docosanol
  • abreva
  • behenic alcohol
  • behenyl alcohol
  • docosyl alcohol
  • 1-Docosanol
  • Molecular weight: 326.61
  • Formula: C22H46O
  • CLOGP: 10.35
  • LIPINSKI: 1
  • HAC: 1
  • HDO: 1
  • TPSA: 20.23
  • ALOGS: -7.22
  • ROTB: 20

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
BA (Bioavailability) 0 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

DateAgencyCompanyOrphan
July 25, 2000 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D06BB11 DERMATOLOGICALS
ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
CHEMOTHERAPEUTICS FOR TOPICAL USE
Antivirals
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000998 Antiviral Agents
CHEBI has role CHEBI:22587 antiviral agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Herpes labialis indication 1475003




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Envelope glycoprotein Membrane other INHIBITOR CHEMBL CHEMBL

External reference:

IDSource
4027425 VUID
N0000179260 NUI
D03884 KEGG_DRUG
285039 RXNORM
4027425 VANDF
C0075770 UMLSCUI
CHEBI:31000 CHEBI
CHEMBL1200453 ChEMBL_ID
DB00632 DRUGBANK_ID
C529236 MESH_SUPPLEMENTAL_RECORD_UI
12620 PUBCHEM_CID
9G1OE216XY UNII
15675 MMSL
313096 MMSL
37939 MMSL
009100 NDDF
411095000 SNOMEDCT_US
736813006 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
ABREVA HUMAN OTC DRUG LABEL 1 0135-0200 CREAM 100 mg TOPICAL NDA 14 sections
ABREVA HUMAN OTC DRUG LABEL 1 0135-0300 CREAM 100 mg TOPICAL ANDA 14 sections
Docosanol HUMAN OTC DRUG LABEL 1 0363-2981 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 0363-9220 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 0363-9222 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 0363-9222 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 0472-2981 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 0591-2981 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11673-846 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11673-926 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11822-0951 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11822-3927 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11822-3951 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11822-3977 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 11822-4763 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 21130-422 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 21130-823 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister HUMAN OTC DRUG LABEL 1 30142-322 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister Treatment HUMAN OTC DRUG LABEL 1 30142-981 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Fever Blister HUMAN OTC DRUG LABEL 1 37808-223 CREAM 100 mg TOPICAL ANDA 13 sections
Cold Sore Treatment HUMAN OTC DRUG LABEL 1 37808-229 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 41163-722 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 41163-724 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 41250-867 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 41250-932 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 46122-624 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 46122-681 CREAM 100 mg TOPICAL ANDA 13 sections
Docosanol HUMAN OTC DRUG LABEL 1 49035-259 CREAM 100 mg TOPICAL ANDA 13 sections
ABREVA HUMAN OTC DRUG LABEL 1 50090-3476 CREAM 100 mg TOPICAL NDA 15 sections
Docosanol HUMAN OTC DRUG LABEL 1 55301-877 CREAM 100 mg TOPICAL ANDA 13 sections