bemegride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3013 64-65-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bemegride
  • bemegrid
  • etimid
  • eukraton
  • megimid
  • megibal
  • megimide
  • methetharimide
  • mikedimide
  • zentraleptin
A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
  • Molecular weight: 155.20
  • Formula: C8H13NO2
  • CLOGP: 0.95
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 46.17
  • ALOGS: -0.79
  • ROTB: 1

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,ERBB2,FLT3,GRK2,ITK,MAP3K21,MAPK7,NTRK2,PDK1,PIK3CD,PRKDC,SIK2,SIK3,STK33,TEK,ULK1 26
kinase-selectivity-class ACVR2B,AXL,BRAF,CDK9,GRK2,MAPK7,STK33 7
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R07AB05 RESPIRATORY SYSTEM
OTHER RESPIRATORY SYSTEM PRODUCTS
OTHER RESPIRATORY SYSTEM PRODUCTS
Respiratory stimulants
MeSH PA D000697 Central Nervous System Stimulants
MeSH PA D003292 Convulsants
MeSH PA D019141 Respiratory System Agents

Related Drugs by ATC class:

R07AB Respiratory stimulants 8 drugs
almitrinedimeflinedoxaprametamivanmepixanoxnikethamidepentetrazolprethcamide

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.98 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01957 KEGG_DRUG
C0004960 UMLSCUI
CHEBI:92269 CHEBI
CHEMBL1214192 ChEMBL_ID
DB13740 DRUGBANK_ID
D001534 MESH_DESCRIPTOR_UI
2310 PUBCHEM_CID
511 INN_ID
57DQA39DO2 UNII
001380 NDDF

Pharmaceutical products:

None