tacrolimus 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
immunosuppressants, rapamycin derivatives 2552 104987-11-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • FK-506
  • tacrolimus hydrate
  • tacrolimus
  • fujimycin
  • tsukubaenolide
  • anhydrous tacrolimus
  • tacrolimus anhydrous
  • modigraf
  • FR900506
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
  • Molecular weight: 804.03
  • Formula: C44H69NO12
  • CLOGP: 5.78
  • LIPINSKI: 3
  • HAC: 13
  • HDO: 3
  • TPSA: 178.36
  • ALOGS: -5.30
  • ROTB: 7
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
5 mg O
5 mg P

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 2 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 0.01 mg/mL Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 0.50 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 0.24 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability) 25 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 1.20 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 0.70 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.01 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 26 hours Lombardo F, Berellini G, Obach RS

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,CDK5,EIF2AK3,GRK2,ITK,NTRK2,PDK1,PDK2,PDK4,PRKDC 10
mdck-mdr1-bcrp-efflux MDCK-MDR1-BCRP efflux ratio 3.990 High 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0
rat-kpuu-brain Rat brain Kpuu 0.045 % High 1

Approvals:

DateAgencyCompanyOrphan
April 8, 1994 FDA ASTELLAS
Feb. 27, 2002 EMA LEO PHARMA A/S

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 5489.75 10.92 1709 181688 11049 90434001
Post transplant lymphoproliferative disorder 3826.64 10.92 1126 182271 5823 90439227
Cytomegalovirus infection 3701.34 10.92 1545 181852 25057 90419993
Thrombotic microangiopathy 2948.50 10.92 1133 182264 14610 90430440
Immunosuppressant drug level increased 2314.19 10.92 698 182699 3982 90441068
Kidney transplant rejection 1812.13 10.92 584 182813 4273 90440777
Epstein-Barr virus infection 1782.56 10.92 701 182696 9643 90435407
Cytomegalovirus viraemia 1656.19 10.92 611 182786 6975 90438075
Polyomavirus-associated nephropathy 1536.66 10.92 441 182956 2049 90443001
Transplant dysfunction 1515.30 10.92 521 182876 4761 90440289
BK virus infection 1318.87 10.92 451 182946 4047 90441003
Liver transplant rejection 1165.29 10.92 328 183069 1400 90443650
Off label use 1165.16 10.92 4848 178549 1097404 89347646
Posterior reversible encephalopathy syndrome 1161.08 10.92 662 182735 21677 90423373
Complications of transplanted kidney 1106.15 10.92 354 183043 2524 90442526
Cytomegalovirus infection reactivation 1027.19 10.92 436 182961 7364 90437686
Acute kidney injury 1024.57 10.92 2102 181295 318285 90126765
Renal impairment 1013.26 10.92 1156 182241 104265 90340785
Product use in unapproved indication 1008.81 10.92 2149 181248 334087 90110963
Multiple organ dysfunction syndrome 995.85 10.92 937 182460 67399 90377651
Drug interaction 950.80 10.92 1870 181527 274583 90170467
Acute graft versus host disease 922.48 10.92 365 183032 5103 90439947
Aspergillus infection 875.54 10.92 431 182966 10392 90434658
Graft versus host disease 867.15 10.92 392 183005 7752 90437298
Drug level increased 863.82 10.92 594 182803 27168 90417882
Fatigue 854.12 10.92 656 182741 1153367 89291683
Pneumocystis jirovecii pneumonia 834.01 10.92 529 182868 21087 90423963
Bronchopulmonary aspergillosis 833.94 10.92 424 182973 10974 90434076
Acute graft versus host disease in skin 769.34 10.92 308 183089 4448 90440602
Smooth muscle cell neoplasm 753.45 10.92 222 183175 1151 90443899
Transplant failure 747.71 10.92 240 183157 1729 90443321
Nephropathy toxic 740.96 10.92 406 182991 12282 90432768
Chronic graft versus host disease 739.42 10.92 288 183109 3851 90441199
COVID-19 717.84 10.92 1252 182145 167591 90277459
Joint swelling 707.64 10.92 92 183305 503208 89941842
Klebsiella infection 698.35 10.92 364 183033 9933 90435117
Nocardiosis 696.51 10.92 243 183154 2327 90442723
Polyomavirus viraemia 688.04 10.92 205 183192 1112 90443938
Septic shock 668.81 10.92 838 182559 83322 90361728
Premature delivery 651.53 10.92 576 182821 38186 90406864
Pain 650.49 10.92 637 182760 995704 89449346
Epstein-Barr virus associated lymphoproliferative disorder 642.31 10.92 231 183166 2436 90442614
Parvovirus B19 infection 624.42 10.92 179 183218 827 90444223
Pemphigus 619.29 10.92 8 183389 326856 90118194
Arthropathy 616.31 10.92 30 183367 366212 90078838
Trichodysplasia spinulosa 611.09 10.92 163 183234 541 90444509
Immunosuppressant drug level decreased 605.47 10.92 181 183216 995 90444055
Glossodynia 604.75 10.92 9 183388 321770 90123280
Synovitis 604.26 10.92 13 183384 329739 90115311
Escherichia infection 600.73 10.92 384 183013 15511 90429539
Diffuse large B-cell lymphoma 598.89 10.92 310 183087 8335 90436715
Renal transplant failure 594.84 10.92 177 183220 955 90444095
Infusion related reaction 586.10 10.92 76 183321 416704 90028346
Delayed graft function 575.35 10.92 182 183215 1243 90443807
Enterococcal infection 573.20 10.92 316 183081 9675 90435375
Arthralgia 571.36 10.92 445 182952 778077 89666973
Graft versus host disease in gastrointestinal tract 556.98 10.92 239 183158 4149 90440901
Adenovirus infection 551.53 10.92 241 183156 4381 90440669
Haemophagocytic lymphohistiocytosis 551.07 10.92 360 183037 15099 90429951
Hypersensitivity 541.34 10.92 128 183269 454549 89990501
Dermatitis atopic 536.76 10.92 417 182980 23055 90421995
Swelling 514.84 10.92 110 183287 418948 90026102
Sepsis 513.68 10.92 1128 182269 178686 90266364
Leukopenia 507.00 10.92 806 182591 99904 90345146
Respiratory failure 505.47 10.92 880 182517 117538 90327512
Contraindicated product administered 500.26 10.92 39 183358 320100 90124950
Drug hypersensitivity 486.30 10.92 166 183231 463443 89981607
Chronic allograft nephropathy 475.63 10.92 138 183259 671 90444379
Wound 470.34 10.92 38 183359 302942 90142108
Epstein-Barr viraemia 460.80 10.92 155 183242 1315 90443735
Peripheral swelling 450.72 10.92 138 183259 412968 90032082
Graft versus host disease in skin 447.10 10.92 197 183200 3656 90441394
Histoplasmosis disseminated 446.03 10.92 170 183227 2135 90442915
Abdominal discomfort 444.75 10.92 205 183192 477123 89967927
Blood creatinine increased 442.54 10.92 761 182636 100625 90344425
Dizziness 441.86 10.92 329 183068 588955 89856095
Pseudomonas infection 441.09 10.92 309 183088 14556 90430494
Ovarian cyst 440.81 10.92 328 183069 16990 90428060
Mucormycosis 435.76 10.92 193 183204 3628 90441422
Dyspnoea 416.70 10.92 716 182681 880239 89564811
Phaeohyphomycosis 415.31 10.92 111 183286 372 90444678
Helicobacter infection 415.22 10.92 9 183388 226841 90218209
Drug ineffective for unapproved indication 411.77 10.92 587 182810 66057 90378993
Kidney fibrosis 404.55 10.92 157 183240 2077 90442973
Systemic lupus erythematosus 403.63 10.92 116 183281 361780 90083270
Human herpesvirus 6 infection 396.71 10.92 175 183222 3257 90441793
Post transplant distal limb syndrome 386.14 10.92 99 183298 268 90444782
Pericarditis 382.59 10.92 48 183349 270103 90174947
Aplasia pure red cell 379.29 10.92 193 183204 5001 90440049
Bacteraemia 377.91 10.92 333 183064 21967 90423083
Pain in extremity 375.98 10.92 223 183174 450306 89994744
Fibromyalgia 374.33 10.92 9 183388 206260 90238790
Folliculitis 370.53 10.92 9 183388 204344 90240706
Cytomegalovirus colitis 370.04 10.92 166 183231 3220 90441830
Nasopharyngitis 365.12 10.92 184 183213 406920 90038130
Irritable bowel syndrome 362.07 10.92 13 183384 207435 90237615
Mobility decreased 358.85 10.92 43 183354 250691 90194359
Heart transplant rejection 354.08 10.92 111 183286 733 90444317
Haemolytic uraemic syndrome 353.14 10.92 152 183245 2659 90442391
Renal tubular necrosis 351.19 10.92 267 183130 14288 90430762
Pathogen resistance 349.38 10.92 213 183184 7902 90437148
Pulmonary nocardiosis 347.56 10.92 108 183289 690 90444360
Malacoplakia 346.58 10.92 89 183308 243 90444807
Sinusitis 344.01 10.92 132 183265 342956 90102094
Fall 339.53 10.92 286 183111 481524 89963526
Psoriatic arthropathy 337.25 10.92 35 183362 228300 90216750
Malaise 331.49 10.92 420 182977 585566 89859484
Focal segmental glomerulosclerosis 331.35 10.92 129 183268 1722 90443328
Cytomegalovirus test positive 326.64 10.92 155 183242 3436 90441614
Chronic graft versus host disease in skin 323.59 10.92 114 183283 1126 90443924
Musculoskeletal stiffness 323.36 10.92 99 183298 296433 90148617
JC virus infection 321.90 10.92 141 183256 2578 90442472
Hypogammaglobulinaemia 321.64 10.92 224 183173 10450 90434600
Pneumonia cytomegaloviral 316.20 10.92 145 183252 2966 90442084
Toxicity to various agents 313.95 10.92 1283 182114 286563 90158487
Graft loss 313.45 10.92 88 183309 371 90444679
Acute graft versus host disease in intestine 313.16 10.92 128 183269 1955 90443095
Hepatic enzyme increased 313.12 10.92 170 183227 360566 90084484
Lower respiratory tract infection 311.29 10.92 64 183333 250595 90194455
Atypical haemolytic uraemic syndrome 308.68 10.92 104 183293 887 90444163
Strongyloidiasis 305.84 10.92 117 183280 1485 90443565
Therapeutic product effect decreased 303.86 10.92 92 183305 277479 90167571
Wheezing 303.61 10.92 57 183340 238023 90207027
Lung transplant rejection 299.77 10.92 103 183294 938 90444112
Brain abscess 298.21 10.92 135 183262 2677 90442373
Nausea 296.59 10.92 1201 182196 1109115 89335935
Headache 296.53 10.92 836 182561 861910 89583140
Renal tubular injury 296.34 10.92 107 183290 1142 90443908
Pre-eclampsia 294.11 10.92 215 183182 10833 90434217
Acne 293.01 10.92 324 183073 28183 90416867
Human polyomavirus infection 284.54 10.92 81 183316 363 90444687
Venoocclusive liver disease 283.15 10.92 167 183230 5826 90439224
Hypoaesthesia 283.14 10.92 141 183256 314069 90130981
Varicella zoster virus infection 282.92 10.92 144 183253 3733 90441317
Viraemia 280.07 10.92 111 183286 1558 90443492
Cystitis haemorrhagic 279.99 10.92 161 183236 5352 90439698
Systemic mycosis 278.74 10.92 108 183289 1422 90443628
Confusional state 277.22 10.92 225 183172 385980 90059070
Weight increased 276.46 10.92 263 183134 417664 90027386
Proteinuria 273.36 10.92 284 183113 23007 90422043
Renal failure 273.09 10.92 728 182669 130279 90314771
Herpes simplex 273.00 10.92 199 183198 9982 90435068
Human herpesvirus 8 infection 271.74 10.92 76 183321 315 90444735
Infection reactivation 270.62 10.92 113 183284 1827 90443223
Injury 269.99 10.92 39 183358 197310 90247740
Pneumatosis intestinalis 269.42 10.92 134 183263 3303 90441747
Type 2 diabetes mellitus 267.09 10.92 45 183352 203199 90241851
Completed suicide 264.43 10.92 6 183391 145052 90299998
Disease recurrence 263.08 10.92 352 183045 37301 90407749
Pancytopenia 262.61 10.92 680 182717 119583 90325467
West Nile viral infection 261.60 10.92 79 183318 452 90444598
Blister 260.74 10.92 95 183302 254903 90190147
Blood cholesterol increased 260.56 10.92 52 183345 207960 90237090
Viral haemorrhagic cystitis 260.02 10.92 102 183295 1391 90443659
Lymphoproliferative disorder 253.29 10.92 138 183259 4124 90440926
Renal graft infection 249.98 10.92 71 183326 315 90444735
Systemic candida 249.66 10.92 144 183253 4815 90440235
Candida infection 245.04 10.92 323 183074 33734 90411316
Ill-defined disorder 245.02 10.92 40 183357 184851 90260199
Epstein-Barr virus infection reactivation 244.08 10.92 100 183297 1537 90443513
Acute respiratory distress syndrome 239.53 10.92 293 183104 28393 90416657
Scedosporium infection 238.92 10.92 82 183315 744 90444306
Alternaria infection 238.28 10.92 68 183329 308 90444742
Drug resistance 238.21 10.92 301 183096 30148 90414902
Cryptococcosis 236.99 10.92 95 183302 1376 90443674
Contusion 236.62 10.92 106 183291 251110 90193940
Urticaria 233.47 10.92 175 183222 312559 90132491
End stage renal disease 233.16 10.92 169 183228 8402 90436648
Dry mouth 232.65 10.92 45 183352 184014 90261036
Insomnia 231.00 10.92 201 183196 333273 90111777
Osteoarthritis 228.90 10.92 57 183340 195673 90249377
Lymphocele 228.71 10.92 79 183318 732 90444318
Impaired healing 228.25 10.92 94 183303 234105 90210945
Asthenia 227.65 10.92 461 182936 533290 89911760
Musculoskeletal pain 222.61 10.92 39 183358 171212 90273838
Toxoplasmosis 222.52 10.92 96 183301 1689 90443361
Progressive multifocal leukoencephalopathy 220.86 10.92 211 183186 15444 90429606
Diabetes mellitus 218.86 10.92 436 182961 64439 90380611
Discomfort 217.29 10.92 144 183253 274191 90170859
Depression 217.04 10.92 174 183223 300427 90144623
Muscle spasms 213.69 10.92 122 183275 251761 90193289
Pyelonephritis 213.44 10.92 239 183158 21077 90423973
Rheumatoid arthritis 213.09 10.92 252 183145 362362 90082688
Bursitis 211.35 10.92 14 183383 131640 90313410
Renal transplant 211.14 10.92 91 183306 1597 90443453
General physical health deterioration 210.59 10.92 245 183152 354870 90090180
Rash 208.98 10.92 866 182531 795234 89649816
Chest pain 207.96 10.92 204 183193 319441 90125609
Hepatitis C 207.07 10.92 134 183263 5526 90439524
Drug intolerance 204.39 10.92 371 183026 447220 89997830
Anxiety 203.50 10.92 196 183201 309576 90135474
Memory impairment 200.73 10.92 74 183323 197170 90247880
Asthma 200.17 10.92 121 183276 242039 90203011
Mycobacterial infection 199.81 10.92 95 183302 2115 90442935
Meningitis cryptococcal 197.55 10.92 89 183308 1744 90443306
Exposure during pregnancy 195.50 10.92 977 182420 237433 90207617
Stomatitis 194.57 10.92 162 183235 274536 90170514
Cerebral toxoplasmosis 189.83 10.92 80 183317 1325 90443725
Pancreas transplant rejection 189.11 10.92 48 183349 123 90444927
Joint range of motion decreased 187.38 10.92 26 183371 135617 90309433
Neurotoxicity 186.95 10.92 224 183173 21243 90423807
Paraesthesia 186.89 10.92 140 183257 250186 90194864
C-reactive protein abnormal 186.89 10.92 20 183377 127409 90317641
Renal tubular atrophy 184.30 10.92 70 183327 870 90444180
Staphylococcal infection 179.82 10.92 339 183058 48100 90396950
Pneumonia bacterial 179.70 10.92 172 183225 12618 90432432
Pulmonary mucormycosis 179.15 10.92 61 183336 539 90444511
Back pain 177.30 10.92 229 183168 316946 90128104
Drug level decreased 176.35 10.92 151 183246 9579 90435471
Acute graft versus host disease in liver 176.18 10.92 65 183332 741 90444309
Ureaplasma infection 176.02 10.92 67 183330 838 90444212
Lip dry 173.79 10.92 7 183390 100948 90344102
Abortion spontaneous 173.64 10.92 356 183041 53700 90391350
Hepatitis E 172.82 10.92 82 183315 1817 90443233
Chronic kidney disease 172.52 10.92 340 183057 49851 90395199
Gait inability 170.54 10.92 43 183354 146413 90298637
Blastomycosis 170.17 10.92 55 183342 406 90444644
Constipation 169.93 10.92 190 183207 280205 90164845
Grip strength decreased 164.31 10.92 5 183392 92571 90352479
Encephalitis viral 164.09 10.92 79 183318 1810 90443240
Cholangitis 162.87 10.92 127 183270 7055 90437995
Abdominal pain upper 162.53 10.92 264 183133 332410 90112640
New onset diabetes after transplantation 161.59 10.92 43 183354 141 90444909
Dyspepsia 160.98 10.92 101 183296 198059 90246991
Pneumonia fungal 160.90 10.92 125 183272 6906 90438144
Tubulointerstitial nephritis 159.08 10.92 225 183172 25118 90419932
COVID-19 pneumonia 158.82 10.92 190 183207 17987 90427063
Nephrotic syndrome 158.30 10.92 126 183271 7213 90437837
Escherichia urinary tract infection 157.71 10.92 166 183231 13649 90431401
Shock haemorrhagic 157.69 10.92 157 183240 12088 90432962
Cytomegalovirus enteritis 156.37 10.92 49 183348 323 90444727
Complications of transplanted liver 155.65 10.92 50 183347 361 90444689
Road traffic accident 155.03 10.92 18 183379 107608 90337442
Drug ineffective 154.78 10.92 3774 179623 1380524 89064526
Immune reconstitution inflammatory syndrome 154.60 10.92 122 183275 6897 90438153
Obesity 153.59 10.92 17 183380 105490 90339560
Premature baby 153.52 10.92 220 183177 24857 90420193
Infective aneurysm 152.53 10.92 50 183347 388 90444662
Donor specific antibody present 152.09 10.92 43 183354 187 90444863
Peripheral venous disease 150.91 10.92 4 183393 83917 90361133
Gait disturbance 150.86 10.92 183 183214 260313 90184737
Fungal infection 150.27 10.92 292 183105 42369 90402681
Migraine 149.28 10.92 101 183296 190291 90254759
Prescribed overdose 149.27 10.92 13 183384 97612 90347438
Acute myeloid leukaemia recurrent 148.93 10.92 76 183321 1981 90443069
Disseminated intravascular coagulation 148.37 10.92 200 183197 21338 90423712
Night sweats 147.63 10.92 39 183358 128727 90316323
Enterobacter infection 146.23 10.92 81 183316 2502 90442548
Cryptosporidiosis infection 145.81 10.92 48 183349 378 90444672
Haemolytic anaemia 145.17 10.92 147 183250 11550 90433500
Encephalopathy 144.63 10.92 302 183095 46142 90398908
Complications of transplanted lung 143.94 10.92 46 183351 326 90444724
Drug level fluctuating 143.27 10.92 50 183347 479 90444571
Urinary tract infection 142.79 10.92 1083 182314 304549 90140501
Cytomegalovirus chorioretinitis 140.09 10.92 77 183320 2342 90442708
Liver injury 139.83 10.92 86 183311 170481 90274569
Stenotrophomonas infection 139.60 10.92 78 183319 2451 90442599
Knee arthroplasty 139.14 10.92 7 183390 83175 90361875
Locked-in syndrome 139.03 10.92 48 183349 444 90444606
Sciatica 138.69 10.92 20 183377 101362 90343688
Glomerulonephritis 138.59 10.92 77 183320 2393 90442657
Decreased appetite 137.05 10.92 354 183043 376186 90068864
Arthritis 136.28 10.92 85 183312 167230 90277820
Low birth weight baby 136.21 10.92 129 183268 9338 90435712
Papilloma viral infection 135.33 10.92 68 183329 1714 90443336
Emphysematous pyelonephritis 133.32 10.92 43 183354 315 90444735
Cytomegalovirus gastrointestinal infection 130.72 10.92 44 183353 374 90444676
Adverse event 130.06 10.92 38 183359 117380 90327670
Escherichia bacteraemia 129.16 10.92 101 183296 5634 90439416
Microangiopathic haemolytic anaemia 128.86 10.92 52 183345 767 90444283
Deep vein thrombosis postoperative 128.75 10.92 3 183394 70806 90374244
Norovirus infection 127.35 10.92 66 183331 1778 90443272
Graft versus host disease in liver 127.33 10.92 54 183343 909 90444141
Histoplasmosis 127.21 10.92 70 183327 2134 90442916
Oesophageal candidiasis 125.85 10.92 107 183290 6722 90438328
Somnolence 125.20 10.92 143 183254 208941 90236109
Mycobacterium abscessus infection 124.84 10.92 55 183342 1020 90444030
Vaccination failure 124.73 10.92 57 183340 1156 90443894
Ascites 124.39 10.92 289 183108 47451 90397599
Pulmonary fibrosis 124.31 10.92 32 183365 107471 90337579
IgA nephropathy 123.40 10.92 52 183345 861 90444189
Syncope 123.25 10.92 57 183340 132606 90312444
Chest discomfort 123.15 10.92 63 183334 138302 90306748
Drug abuse 123.13 10.92 12 183385 82335 90362715
Hip arthroplasty 122.60 10.92 8 183389 76200 90368850
Complications of transplant surgery 121.85 10.92 35 183362 163 90444887
Squamous cell carcinoma of skin 121.74 10.92 109 183288 7340 90437710
Lymphopenia 120.39 10.92 187 183210 22694 90422356
Squamous cell carcinoma 120.01 10.92 124 183273 9977 90435073
Hydronephrosis 118.96 10.92 136 183261 12266 90432784
Alveolar proteinosis 118.76 10.92 50 183347 826 90444224
Graft complication 118.10 10.92 38 183359 276 90444774
Feeling abnormal 117.89 10.92 99 183298 167136 90277914
Autoimmune haemolytic anaemia 117.67 10.92 95 183302 5550 90439500
Epidermodysplasia verruciformis 117.56 10.92 33 183364 139 90444911
Mycoplasma infection 117.56 10.92 50 183347 848 90444202
Cat scratch disease 117.42 10.92 37 183360 249 90444801
Hypercholesterolaemia 116.72 10.92 30 183367 100862 90344188
Liver abscess 116.30 10.92 78 183319 3418 90441632
Splenomegaly 116.06 10.92 137 183260 12787 90432263
Organising pneumonia 116.00 10.92 107 183290 7490 90437560
Gestational hypertension 115.74 10.92 74 183323 2988 90442062
Human ehrlichiosis 115.42 10.92 34 183363 176 90444874
Drug level above therapeutic 115.28 10.92 95 183302 5714 90439336
Chronic obstructive pulmonary disease 115.17 10.92 9 183388 73820 90371230
Enterocolitis 114.35 10.92 123 183274 10367 90434683
Gastroenteritis norovirus 114.32 10.92 67 183330 2309 90442741
Cerebral aspergillosis 113.39 10.92 43 183354 532 90444518
Hepatosplenic T-cell lymphoma 113.06 10.92 45 183352 639 90444411
Gastrooesophageal reflux disease 112.97 10.92 102 183295 166235 90278815
Weight decreased 112.47 10.92 393 183004 379517 90065533
Vomiting 112.45 10.92 1037 182360 787256 89657794
Disseminated aspergillosis 112.27 10.92 41 183356 453 90444597
Cytomegalovirus enterocolitis 112.22 10.92 48 183349 826 90444224
Rhodococcus infection 111.91 10.92 31 183366 123 90444927
Obliterative bronchiolitis 111.91 10.92 69 183328 2612 90442438
Product dose omission issue 111.73 10.92 267 183130 291420 90153630
Disseminated mycobacterium avium complex infection 110.89 10.92 35 183362 237 90444813
Muscular weakness 110.55 10.92 154 183243 206512 90238538
Engraftment syndrome 110.52 10.92 45 183352 680 90444370
Hepatic failure 109.59 10.92 246 183151 39482 90405568
Citrobacter infection 108.61 10.92 44 183353 656 90444394
Intentional overdose 108.36 10.92 28 183369 93806 90351244
Renal tubular acidosis 108.03 10.92 64 183333 2251 90442799
Cytomegalovirus oesophagitis 107.62 10.92 38 183359 378 90444672
Sleep disorder 107.50 10.92 146 183251 197884 90247166
Hyperhidrosis 107.24 10.92 72 183325 136233 90308817
Lower limb fracture 106.93 10.92 21 183376 84992 90360058
Glomerulosclerosis 106.57 10.92 40 183357 480 90444570
Glomerulonephritis membranoproliferative 106.04 10.92 36 183361 315 90444735
Eczema 105.26 10.92 289 183108 52581 90392469
Mycobacterium avium complex infection 105.13 10.92 78 183319 4020 90441030
Epstein-Barr virus test positive 105.12 10.92 43 183354 658 90444392
Therapy partial responder 104.78 10.92 172 183225 21871 90423179
Graft versus host disease in lung 104.39 10.92 40 183357 510 90444540
Oesophageal ulcer 104.28 10.92 85 183312 5034 90440016
Clostridium difficile colitis 104.23 10.92 191 183206 26515 90418535
Cytomegalovirus gastritis 102.82 10.92 35 183362 309 90444741
Red blood cell sedimentation rate increased 102.64 10.92 21 183376 82574 90362476
Reversible cerebral vasoconstriction syndrome 102.36 10.92 77 183320 4053 90440997
Bacterial infection 102.22 10.92 176 183221 23268 90421782
Polyomavirus test positive 102.05 10.92 26 183371 68 90444982
Venoocclusive disease 102.01 10.92 63 183334 2392 90442658
Perinephric abscess 101.95 10.92 34 183363 280 90444770
Disseminated toxoplasmosis 101.57 10.92 30 183367 157 90444893
Infection in an immunocompromised host 100.86 10.92 45 183352 861 90444189
Passenger lymphocyte syndrome 100.46 10.92 26 183371 74 90444976
Fungal skin infection 99.62 10.92 84 183313 5217 90439833
Dislocation of vertebra 99.40 10.92 3 183394 55965 90389085
Klebsiella bacteraemia 98.86 10.92 63 183334 2529 90442521
Prophylaxis against transplant rejection 98.81 10.92 22 183375 23 90445027
Amnesia 98.67 10.92 48 183349 108457 90336593
Autoimmune disorder 98.56 10.92 18 183379 76726 90368324
Bone marrow failure 98.55 10.92 208 183189 32013 90413037
SARS-CoV-2 RNA increased 98.51 10.92 27 183370 102 90444948
Neutropenia 98.34 10.92 785 182612 224119 90220931
Peritonitis 98.08 10.92 157 183240 19548 90425502
Thrombotic thrombocytopenic purpura 97.82 10.92 75 183322 4063 90440987
Ureteric stenosis 97.73 10.92 41 183356 671 90444379
Chronic myeloid leukaemia 97.28 10.92 63 183334 2601 90442449
Brain oedema 96.99 10.92 146 183251 17239 90427811
Alopecia 96.75 10.92 596 182801 494475 89950575
Joint stiffness 96.65 10.92 20 183377 78022 90367028
Angiosarcoma 96.48 10.92 31 183366 224 90444826
Nail disorder 95.61 10.92 6 183391 59061 90385989
Disseminated cryptococcosis 94.69 10.92 41 183356 728 90444322
Visceral leishmaniasis 94.57 10.92 39 183358 610 90444440
Neck pain 94.03 10.92 57 183340 113906 90331144
Transplantation associated food allergy 93.35 10.92 21 183376 24 90445026
Anti-erythropoietin antibody negative 93.30 10.92 26 183371 106 90444944
Graft thrombosis 93.22 10.92 30 183367 218 90444832
MELAS syndrome 93.09 10.92 29 183368 187 90444863
Encapsulating peritoneal sclerosis 92.60 10.92 33 183364 338 90444712
Proteus infection 92.32 10.92 50 183347 1476 90443574
Flushing 92.03 10.92 32 183365 88459 90356591
Hepatitis B 91.98 10.92 75 183322 4444 90440606
Encephalitis 91.77 10.92 113 183284 11021 90434029
Blepharospasm 91.68 10.92 5 183392 55440 90389610
Pneumonia klebsiella 91.45 10.92 64 183333 3008 90442042
Leukoencephalopathy 91.13 10.92 77 183320 4796 90440254
Foot deformity 91.03 10.92 8 183389 59643 90385407
Encephalitis cytomegalovirus 90.56 10.92 39 183358 683 90444367
Disseminated tuberculosis 89.62 10.92 65 183332 3234 90441816
Pneumomediastinum 89.20 10.92 54 183343 1977 90443073
Hyperammonaemia 88.93 10.92 86 183311 6389 90438661
Multiple sclerosis relapse 88.77 10.92 4 183393 52301 90392749
Renal abscess 88.74 10.92 44 183353 1077 90443973
Human herpesvirus 6 infection reactivation 88.67 10.92 37 183360 597 90444453
Intestine transplant rejection 88.23 10.92 22 183375 51 90444999
Pyelonephritis acute 87.81 10.92 79 183318 5353 90439697
Pneumonia cryptococcal 87.72 10.92 45 183352 1186 90443864
Disseminated cytomegaloviral infection 87.52 10.92 30 183367 271 90444779
Urinary tract infection bacterial 87.31 10.92 84 183313 6201 90438849
Chronic graft versus host disease in liver 87.21 10.92 31 183366 315 90444735
Thrombocytopenia 86.63 10.92 720 182677 208005 90237045
Pleural effusion 86.13 10.92 451 182946 111540 90333510
Haemorrhage intracranial 85.54 10.92 128 183269 15034 90430016
Periostitis 84.86 10.92 33 183364 439 90444611
Epstein-Barr virus associated lymphoma 84.74 10.92 37 183360 671 90444379
Hyperuricaemia 84.40 10.92 85 183312 6634 90438416
Anogenital warts 83.98 10.92 35 183362 563 90444487
Liver transplant failure 83.87 10.92 19 183378 23 90445027
Balance disorder 83.73 10.92 46 183351 97034 90348016
Feeling hot 83.23 10.92 27 183370 77981 90367069
Lung transplant 83.10 10.92 65 183332 3627 90441423
Oedema peripheral 83.04 10.92 257 183140 257658 90187392
Pneumonia pseudomonal 82.25 10.92 61 183336 3142 90441908
Clostridium difficile infection 82.20 10.92 208 183189 36037 90409013
Splenic abscess 81.97 10.92 28 183369 250 90444800
Cerebral fungal infection 81.88 10.92 28 183369 251 90444799
Human herpesvirus 6 encephalitis 81.85 10.92 31 183366 382 90444668
Eye infection toxoplasmal 81.20 10.92 31 183366 391 90444659
C-reactive protein increased 81.18 10.92 152 183245 181237 90263813
Acute respiratory failure 80.90 10.92 230 183167 42688 90402362
Herpes simplex hepatitis 80.63 10.92 34 183363 564 90444486
Complications of transplanted heart 80.45 10.92 23 183374 105 90444945
Bacterial sepsis 79.98 10.92 72 183325 4883 90440167
Genital herpes simplex 79.88 10.92 31 183366 410 90444640
Rhinovirus infection 79.65 10.92 78 183319 5885 90439165
Acinetobacter infection 79.57 10.92 50 183347 1958 90443092
Escherichia sepsis 79.41 10.92 77 183320 5739 90439311
Rectal haemorrhage 79.29 10.92 34 183363 82710 90362340
Enterococcal bacteraemia 79.11 10.92 50 183347 1978 90443072
Oesophageal stenosis 78.78 10.92 64 183333 3772 90441278
Wound infection 78.72 10.92 60 183337 106342 90338708
Liver function test abnormal 78.48 10.92 254 183143 50591 90394459
Actinic keratosis 78.04 10.92 59 183338 3129 90441921
Back injury 77.73 10.92 4 183393 46618 90398432
Coccidioidomycosis 77.54 10.92 41 183356 1152 90443898
Hypertrophic cardiomyopathy 77.23 10.92 51 183346 2177 90442873
Disseminated mucormycosis 76.86 10.92 34 183363 637 90444413
Dermatophytosis 76.49 10.92 25 183372 192 90444858
Interstitial lung disease 76.42 10.92 332 183065 76073 90368977
Malignant neoplasm progression 75.63 10.92 63 183334 106807 90338243
Urosepsis 75.58 10.92 146 183251 21086 90423964
Pulmonary alveolar haemorrhage 75.57 10.92 76 183321 5922 90439128
Hyperglycaemia 75.43 10.92 251 183146 50719 90394331
Product quality issue 75.36 10.92 33 183364 79292 90365758
Nephropathy 74.94 10.92 93 183304 9142 90435908
Infectious pleural effusion 73.95 10.92 47 183350 1878 90443172
Pneumocystis jirovecii infection 73.70 10.92 47 183350 1889 90443161
Babesiosis 73.60 10.92 26 183371 259 90444791
Injection site reaction 73.28 10.92 48 183349 92032 90353018
Intussusception 73.21 10.92 38 183359 1027 90444023
Acanthamoeba infection 72.92 10.92 19 183378 56 90444994
Anuria 72.30 10.92 117 183280 14701 90430349
Heart rate increased 72.25 10.92 73 183324 112829 90332221
Tremor 72.11 10.92 544 182853 152629 90292421
Palpitations 71.99 10.92 103 183294 136625 90308425
Laryngitis 71.82 10.92 9 183388 50744 90394306
Lupus vulgaris 71.69 10.92 5 183392 45054 90399996
Prescribed underdose 71.60 10.92 31 183366 74988 90370062
Influenza like illness 71.28 10.92 37 183360 80574 90364476
Calciphylaxis 70.76 10.92 57 183340 3319 90441731
Meningoencephalitis herpetic 69.83 10.92 41 183356 1418 90443632
Lupus nephritis 69.81 10.92 66 183331 4766 90440284
Fusarium infection 69.80 10.92 37 183360 1045 90444005
Endophthalmitis 69.62 10.92 65 183332 4620 90440430
Pleural mesothelioma malignant 69.61 10.92 18 183379 51 90444999
Drug effective for unapproved indication 69.56 10.92 83 183314 7835 90437215
Parainfluenzae virus infection 68.89 10.92 52 183345 2751 90442299
Subcutaneous abscess 68.89 10.92 76 183321 6590 90438460
Malacoplakia gastrointestinal 68.60 10.92 18 183379 55 90444995
Central nervous system lymphoma 68.52 10.92 46 183351 2019 90443031
Atypical mycobacterial infection 68.25 10.92 42 183355 1584 90443466
Blood pressure increased 68.20 10.92 190 183207 197027 90248023
Varicella 66.79 10.92 48 183349 2354 90442696
Hepatic function abnormal 66.77 10.92 226 183171 46062 90398988
Hepatic artery thrombosis 66.59 10.92 19 183378 86 90444964
Central nervous system viral infection 66.56 10.92 21 183376 142 90444908
Cough 66.52 10.92 455 182942 368507 90076543
Chronic graft versus host disease oral 66.50 10.92 23 183374 214 90444836
Clostridial infection 66.37 10.92 63 183334 4573 90440477
Renal artery stenosis 66.32 10.92 46 183351 2131 90442919
Taste disorder 66.19 10.92 21 183376 61525 90383525
Dry skin 65.87 10.92 352 183045 87721 90357329
Bacillary angiomatosis 65.71 10.92 20 183377 118 90444932
Angiosarcoma metastatic 65.68 10.92 18 183379 68 90444982
Adenoviral hepatitis 65.31 10.92 27 183370 425 90444625
Microtia 64.96 10.92 26 183371 375 90444675
Drug level below therapeutic 64.83 10.92 69 183328 5745 90439305
Renal disorder 64.77 10.92 196 183201 37663 90407387
Pyelonephritis fungal 64.65 10.92 22 183375 194 90444856
Placental insufficiency 64.60 10.92 41 183356 1634 90443416
Haemodialysis 64.52 10.92 84 183313 8663 90436387
Cytomegalovirus hepatitis 64.46 10.92 26 183371 383 90444667
Adenoviral haemorrhagic cystitis 64.39 10.92 21 183376 160 90444890
Pericardial effusion 64.25 10.92 192 183205 36641 90408409
Vesicoureteric reflux 64.25 10.92 24 183373 284 90444766
Device expulsion 63.72 10.92 5 183392 40881 90404169
Malacoplakia vesicae 63.60 10.92 17 183380 57 90444993
Hepatic artery stenosis 63.53 10.92 18 183379 79 90444971
Urinary tract infection enterococcal 63.38 10.92 51 183346 2965 90442085
Candida sepsis 62.61 10.92 40 183357 1613 90443437
Renal necrosis 62.49 10.92 17 183380 62 90444988
BK polyomavirus test positive 62.31 10.92 20 183377 144 90444906
Oedema 62.06 10.92 203 183194 200092 90244958
Peliosis hepatis 62.01 10.92 19 183378 115 90444935
Inflammation 61.79 10.92 172 183225 178420 90266630
Gastric ulcer 61.71 10.92 157 183240 27291 90417759
Haemolysis 61.65 10.92 81 183316 8429 90436621
Endocarditis 61.56 10.92 74 183323 7039 90438011
Microsporidia infection 61.53 10.92 24 183373 322 90444728
Staphylococcal sepsis 61.40 10.92 85 183312 9298 90435752
Epstein Barr virus positive mucocutaneous ulcer 61.26 10.92 28 183369 568 90444482
Cytomegalovirus gastroenteritis 60.93 10.92 24 183373 331 90444719
Loss of consciousness 60.57 10.92 120 183277 140118 90304932
Campylobacter infection 60.49 10.92 35 183362 1177 90443873
Dysphonia 60.31 10.92 26 183371 63058 90381992
Heart rate decreased 59.82 10.92 17 183380 53488 90391562
Aplastic anaemia 59.67 10.92 101 183296 13168 90431882
Optic neuropathy 59.64 10.92 47 183350 2651 90442399
Intracranial infection 59.55 10.92 21 183376 208 90444842
Osmotic demyelination syndrome 59.52 10.92 33 183364 1021 90444029
Necrosis 59.24 10.92 70 183327 6540 90438510
Angiocentric lymphoma 59.16 10.92 29 183368 692 90444358
Enterovirus infection 59.15 10.92 37 183360 1437 90443613
Ear infection 58.82 10.92 34 183363 69741 90375309
Hyperkalaemia 58.75 10.92 274 183123 64690 90380360
Toxic encephalopathy 58.73 10.92 80 183317 8619 90436431
Dysplasia 58.50 10.92 36 183361 1358 90443692
Cytopenia 58.50 10.92 117 183280 17332 90427718
Cerebrovascular accident 58.42 10.92 100 183297 123433 90321617
Therapeutic product effect incomplete 58.37 10.92 199 183198 193697 90251353
Bile duct stenosis 58.27 10.92 39 183358 1703 90443347
Trichophytosis 58.26 10.92 16 183381 61 90444989
Joint dislocation 58.24 10.92 10 183387 44572 90400478
Sebaceous carcinoma 58.06 10.92 16 183381 62 90444988
Urinary tract candidiasis 58.00 10.92 29 183368 723 90444327
Cleft palate 57.82 10.92 35 183362 1281 90443769
Haemodynamic instability 57.69 10.92 93 183304 11646 90433404
Penicillium infection 57.66 10.92 22 183375 277 90444773
Biloma 57.55 10.92 17 183380 89 90444961
Lung disorder 57.50 10.92 137 183260 149746 90295304
Perinephric collection 57.40 10.92 18 183379 119 90444931
Underdose 57.09 10.92 19 183378 53998 90391052
Liver transplant 56.98 10.92 43 183354 2274 90442776
Bacterial pyelonephritis 56.97 10.92 25 183372 459 90444591
Agranulocytosis 56.89 10.92 178 183219 34824 90410226
Frequent bowel movements 56.81 10.92 22 183375 56913 90388137
Renal tubular disorder 56.55 10.92 49 183348 3158 90441892
Gastrointestinal disorder 56.55 10.92 297 183100 256390 90188660
Hepatic fibrosis 56.49 10.92 55 183342 4120 90440930
Neutrophil Pelger-Huet anomaly present 56.48 10.92 17 183380 96 90444954
Walking aid user 56.31 10.92 4 183393 35502 90409548
Sarcoma of skin 56.28 10.92 14 183383 32 90445018
Chronic graft versus host disease in eye 56.02 10.92 20 183377 206 90444844
Muscle spasticity 55.96 10.92 4 183393 35318 90409732
Skin mass 55.82 10.92 72 183325 7358 90437692
Pseudomonal bacteraemia 55.79 10.92 40 183357 1954 90443096
Biliary anastomosis complication 55.69 10.92 14 183383 34 90445016
Central nervous system fungal infection 55.44 10.92 18 183379 135 90444915
Heart disease congenital 55.36 10.92 37 183360 1612 90443438
Metastatic squamous cell carcinoma 54.93 10.92 21 183376 266 90444784
Vertigo 54.73 10.92 37 183360 69774 90375276
Encephalitis autoimmune 54.66 10.92 40 183357 2018 90443032
Opportunistic infection 54.60 10.92 41 183356 2152 90442898
Delirium 54.55 10.92 79 183318 104280 90340770
Reticulocytopenia 54.45 10.92 16 183381 82 90444968
Brain herniation 54.35 10.92 54 183343 4146 90440904
Respiratory distress 54.29 10.92 188 183209 38758 90406292
Finger deformity 54.28 10.92 3 183394 32894 90412156
Injection site erythema 54.06 10.92 72 183325 98430 90346620
Chronic graft versus host disease in intestine 54.00 10.92 18 183379 148 90444902
Bradycardia 53.89 10.92 54 183343 83793 90361257
Enterocolitis viral 53.88 10.92 22 183375 335 90444715
Medication error 53.85 10.92 55 183342 84597 90360453
Idiopathic intracranial hypertension 53.83 10.92 50 183347 3531 90441519
Upper respiratory fungal infection 53.54 10.92 19 183378 192 90444858
Linear IgA disease 53.28 10.92 41 183356 2233 90442817
Diffuse alveolar damage 53.01 10.92 31 183366 1064 90443986
Myocardial infarction 52.71 10.92 83 183314 105889 90339161
Sedation 52.59 10.92 16 183381 48155 90396895
Nodular melanoma 52.20 10.92 15 183382 70 90444980
Steroid diabetes 51.93 10.92 42 183355 2460 90442590
Azotaemia 51.89 10.92 59 183338 5289 90439761
Device dislocation 51.55 10.92 3 183394 31479 90413571
Hypoalbuminaemia 51.39 10.92 105 183292 15792 90429258
Placental disorder 51.34 10.92 35 183362 1576 90443474
Skin exfoliation 51.17 10.92 272 183125 67641 90377409
Tuberculosis gastrointestinal 51.15 10.92 22 183375 384 90444666
Oedematous kidney 51.08 10.92 17 183380 139 90444911
Hypokalaemia 50.97 10.92 119 183278 130997 90314053
Dysmorphism 50.97 10.92 42 183355 2526 90442524
Hepatic necrosis 50.91 10.92 64 183333 6374 90438676
Product use issue 50.84 10.92 425 182972 329494 90115556
Oxygen saturation decreased 50.83 10.92 87 183310 107396 90337654
Chromoblastomycosis 50.75 10.92 13 183384 35 90445015
Glomerulonephritis membranous 50.28 10.92 26 183371 697 90444353
Suicide attempt 50.27 10.92 47 183350 75352 90369698
Arteritis infective 50.24 10.92 15 183382 82 90444968
Philadelphia positive chronic myeloid leukaemia 50.23 10.92 13 183384 37 90445013
Plasmablastic lymphoma 50.18 10.92 19 183378 234 90444816
Guillain-Barre syndrome 50.13 10.92 54 183343 4558 90440492
Respiratory syncytial virus infection 50.11 10.92 82 183315 10398 90434652
Premature labour 50.11 10.92 94 183303 13282 90431768
Pancreatitis haemorrhagic 49.97 10.92 25 183372 624 90444426
Gastroenteritis eosinophilic 49.95 10.92 17 183380 150 90444900
Normocytic anaemia 49.94 10.92 44 183353 2900 90442150
Hepatitis viral 49.94 10.92 25 183372 625 90444425
Fungal endocarditis 49.93 10.92 21 183376 346 90444704
Anaemia 49.78 10.92 996 182401 351806 90093244
Wrong technique in product usage process 49.64 10.92 43 183354 71528 90373522
Osteoporosis 49.55 10.92 74 183323 96457 90348593
Cholestasis 49.54 10.92 174 183223 36125 90408925
Retinitis 49.42 10.92 9 183388 38449 90406601
Delayed engraftment 49.40 10.92 16 183381 119 90444931
Cardiac failure congestive 49.37 10.92 77 183320 98617 90346433
Dialysis 49.32 10.92 85 183312 11244 90433806
Trichosporon infection 49.17 10.92 21 183376 360 90444690
Infected neoplasm 49.12 10.92 21 183376 361 90444689
Pain in jaw 48.78 10.92 18 183379 47967 90397083
Coronavirus infection 48.76 10.92 58 183339 5457 90439593
Graft ischaemia 48.65 10.92 15 183382 93 90444957
Macular degeneration 48.55 10.92 9 183388 37961 90407089
Subarachnoid haemorrhage 48.41 10.92 110 183287 17794 90427256
Disseminated varicella zoster virus infection 48.33 10.92 22 183375 442 90444608
Large intestinal ulcer 48.19 10.92 49 183348 3868 90441182
Humoral immune defect 48.19 10.92 21 183376 379 90444671
Complications of bone marrow transplant 48.01 10.92 22 183375 449 90444601
Oliguria 47.95 10.92 81 183316 10543 90434507
Staphylococcal bacteraemia 47.89 10.92 67 183330 7402 90437648
Limb reduction defect 47.79 10.92 24 183373 604 90444446
Skin graft rejection 47.49 10.92 12 183385 30 90445020
Pneumonia influenzal 47.33 10.92 38 183359 2202 90442848
Cytomegalovirus urinary tract infection 47.28 10.92 14 183383 74 90444976
Mediastinitis 47.14 10.92 20 183377 337 90444713
Urinary tract infection viral 47.13 10.92 14 183383 75 90444975
Mycotic endophthalmitis 47.11 10.92 17 183380 181 90444869
Anorexia nervosa 47.10 10.92 19 183378 280 90444770
Lymphocytic infiltration 46.81 10.92 29 183368 1107 90443943
Cytomegalovirus duodenitis 46.65 10.92 13 183384 53 90444997
Hepatitis cholestatic 46.48 10.92 71 183326 8490 90436560
Diabetic ketoacidosis 46.19 10.92 131 183266 24276 90420774
Escherichia pyelonephritis 46.19 10.92 25 183372 737 90444313
Neuroendocrine carcinoma of the skin 46.10 10.92 26 183371 832 90444218
Cystitis viral 46.05 10.92 18 183379 243 90444807
Fluid retention 45.73 10.92 67 183330 88024 90357026
Coagulation test abnormal 45.72 10.92 27 183370 944 90444106
Abdominal wall infection 45.69 10.92 15 183382 117 90444933
Loss of personal independence in daily activities 45.66 10.92 133 183264 135972 90309078
Renal vein thrombosis 45.54 10.92 23 183374 586 90444464
Onychomycosis 45.41 10.92 10 183387 37366 90407684
Vascular hyalinosis 45.41 10.92 12 183385 38 90445012
Lupus-like syndrome 45.33 10.92 21 183376 48825 90396225
Pneumonia pneumococcal 45.07 10.92 40 183357 2662 90442388
Lymphadenopathy 45.07 10.92 198 183199 45577 90399473
Biliary obstruction 44.95 10.92 44 183353 3318 90441732
Orf 44.89 10.92 11 183386 23 90445027
Necrotising retinitis 44.80 10.92 22 183375 527 90444523
Gastritis fungal 44.80 10.92 16 183381 165 90444885
Neuropathy peripheral 44.40 10.92 136 183261 136834 90308216
Cryptococcal cutaneous infection 44.33 10.92 14 183383 95 90444955
Pulmonary haemorrhage 44.28 10.92 67 183330 7946 90437104
Gestational diabetes 44.25 10.92 78 183319 10504 90434546
Hyperglycaemic hyperosmolar nonketotic syndrome 44.24 10.92 30 183367 1339 90443711
Psoriasis 44.22 10.92 152 183245 147602 90297448
Adrenal mass 43.87 10.92 28 183369 1127 90443923
Nosocomial infection 43.75 10.92 34 183363 1879 90443171
Hypotension 43.69 10.92 434 182963 324963 90120087
Ureteral necrosis 43.44 10.92 12 183385 47 90445003
Cervical dysplasia 43.44 10.92 47 183350 3987 90441063
Cutaneous nocardiosis 43.40 10.92 13 183384 72 90444978
Pancreas transplant 43.32 10.92 10 183387 14 90445036
Urate nephropathy 43.14 10.92 15 183382 142 90444908
Serum sickness 43.01 10.92 44 183353 3498 90441552
Foetal growth restriction 42.98 10.92 72 183325 9308 90435742
Engraft failure 42.85 10.92 19 183378 358 90444692
Biliary tract disorder 42.83 10.92 25 183372 855 90444195
Gastrointestinal mucormycosis 42.83 10.92 18 183379 296 90444754
Gastrointestinal lymphoma 42.81 10.92 13 183384 76 90444974
Central nervous system infection 42.80 10.92 25 183372 856 90444194
Herpes simplex oesophagitis 42.78 10.92 16 183381 190 90444860
Distributive shock 42.43 10.92 43 183354 3381 90441669
Hypouricaemia 42.36 10.92 17 183380 247 90444803
Swollen tongue 42.28 10.92 20 183377 45936 90399114
Panophthalmitis 42.23 10.92 15 183382 152 90444898
Treatment failure 42.22 10.92 402 182995 303526 90141524
Abdominal distension 42.10 10.92 130 183267 130471 90314579
Throat irritation 42.09 10.92 23 183374 48672 90396378
Bone pain 42.07 10.92 38 183359 61945 90383105
Illness 41.91 10.92 63 183334 81906 90363144
Viral diarrhoea 41.90 10.92 16 183381 202 90444848
Superinfection bacterial 41.89 10.92 26 183371 996 90444054
Blood pressure systolic increased 41.76 10.92 34 183363 58311 90386739
Truncus arteriosus persistent 41.73 10.92 19 183378 382 90444668
Encephalomalacia 41.34 10.92 21 183376 542 90444508
Aspergillus test positive 41.32 10.92 19 183378 391 90444659
Myalgia 41.19 10.92 198 183199 174927 90270123
Moyamoya disease 41.06 10.92 13 183384 89 90444961
Glomerulonephritis rapidly progressive 41.05 10.92 28 183369 1262 90443788
Fungal sepsis 41.04 10.92 30 183367 1511 90443539
Hot flush 40.94 10.92 36 183361 59452 90385598
Osteonecrosis of jaw 40.89 10.92 14 183383 39089 90405961
Ileal ulcer 40.88 10.92 26 183371 1040 90444010
Cerebral haemorrhage 40.83 10.92 158 183239 34364 90410686
Purpura fulminans 40.69 10.92 13 183384 92 90444958
Adverse drug reaction 40.65 10.92 112 183285 116589 90328461
Herpes zoster 40.58 10.92 329 183068 94315 90350735
Glycosuria 40.52 10.92 29 183368 1413 90443637
Disseminated varicella zoster vaccine virus infection 40.44 10.92 12 183385 64 90444986
Photodermatosis 40.24 10.92 21 183376 574 90444476
Device issue 39.99 10.92 6 183391 29531 90415519
Septic embolus 39.94 10.92 25 183372 972 90444078
Urinary fistula 39.86 10.92 10 183387 24 90445026
Subcapsular renal haematoma 39.85 10.92 18 183379 355 90444695
Adenovirus reactivation 39.59 10.92 16 183381 237 90444813
Paraesthesia oral 39.43 10.92 8 183389 31651 90413399
Fluorosis 39.41 10.92 14 183383 142 90444908
Disseminated blastomycosis 39.11 10.92 12 183385 73 90444977
Neuropsychiatric lupus 38.81 10.92 15 183382 196 90444854
Post procedural bile leak 38.81 10.92 14 183383 149 90444901
Transplant 38.78 10.92 25 183372 1024 90444026
Genital herpes 38.65 10.92 33 183364 2085 90442965
Colon injury 38.52 10.92 16 183381 255 90444795
Drug withdrawal syndrome 38.51 10.92 6 183391 28717 90416333
Full blood count abnormal 38.45 10.92 13 183384 36584 90408466
Mycobacterium chelonae infection 38.28 10.92 21 183376 636 90444414
Bronchitis 38.28 10.92 169 183228 152758 90292292
Drug tolerance decreased 38.23 10.92 9 183388 32121 90412929
Nasal congestion 38.10 10.92 69 183328 83345 90361705
Cutaneous blastomycosis 38.05 10.92 9 183388 15 90445035
Hypertrophic osteoarthropathy 38.00 10.92 10 183387 31 90445019
Paternal exposure during pregnancy 37.97 10.92 17 183380 328 90444722
Metapneumovirus infection 37.86 10.92 27 183370 1308 90443742
Congenital cardiovascular anomaly 37.81 10.92 19 183378 479 90444571
Parvovirus infection 37.77 10.92 19 183378 480 90444570
SARS-CoV-2 viraemia 37.76 10.92 10 183387 32 90445018
Blood lactate dehydrogenase increased 37.74 10.92 127 183270 25805 90419245
Steroid withdrawal syndrome 37.72 10.92 21 183376 655 90444395
Immunosuppressant drug level 37.68 10.92 9 183388 16 90445034
Nephrogenic systemic fibrosis 37.64 10.92 44 183353 4064 90440986
Post procedural urine leak 37.53 10.92 10 183387 33 90445017
Renal haemorrhage 37.53 10.92 25 183372 1083 90443967
Treatment noncompliance 37.49 10.92 205 183192 51522 90393528
Subcutaneous emphysema 37.45 10.92 25 183372 1087 90443963
Hepatic cyst infection 37.39 10.92 13 183384 123 90444927
T-cell lymphoma 37.08 10.92 22 183375 776 90444274
Leukaemia in remission 36.99 10.92 9 183388 18 90445032
Vascular graft complication 36.86 10.92 10 183387 36 90445014
Renal aneurysm 36.86 10.92 10 183387 36 90445014
Haemothorax 36.81 10.92 34 183363 2384 90442666
Renal cortical necrosis 36.80 10.92 16 183381 287 90444763
Injection site bruising 36.80 10.92 31 183366 52276 90392774
Congenital nail disorder 36.73 10.92 12 183385 92 90444958
Gastroenteritis rotavirus 36.47 10.92 15 183382 233 90444817
Oesophageal atresia 36.33 10.92 20 183377 610 90444440
American trypanosomiasis 36.29 10.92 15 183382 236 90444814
Kaposi sarcoma inflammatory cytokine syndrome 36.11 10.92 8 183389 8 90445042
Meningitis 36.10 10.92 63 183334 8418 90436632
Adverse reaction 36.00 10.92 8 183389 29704 90415346
Porokeratosis 35.98 10.92 13 183384 139 90444911
Disseminated trichosporonosis 35.86 10.92 12 183385 100 90444950
External auditory canal atresia 35.84 10.92 11 183386 67 90444983
Urinary tract infection pseudomonal 35.83 10.92 23 183374 935 90444115
Immunosuppression 35.81 10.92 77 183320 12000 90433050
Orthostatic hypotension 35.80 10.92 20 183377 41807 90403243
Upper respiratory tract inflammation 35.78 10.92 35 183362 2637 90442413
Histoplasmosis cutaneous 35.76 10.92 9 183388 22 90445028
Cutaneous malacoplakia 35.76 10.92 9 183388 22 90445028
Stoma closure 35.75 10.92 14 183383 190 90444860
Intervertebral disc protrusion 35.74 10.92 6 183391 27190 90417860
Corynebacterium infection 35.61 10.92 23 183374 945 90444105
Bacteriuria 35.61 10.92 25 183372 1181 90443869
Adult T-cell lymphoma/leukaemia 35.56 10.92 15 183382 249 90444801
Intentional product use issue 35.41 10.92 275 183122 216617 90228433
Renal ischaemia 35.30 10.92 20 183377 646 90444404
Blood potassium decreased 35.18 10.92 27 183370 47700 90397350
Back disorder 35.18 10.92 5 183392 25626 90419424
Hydrocephalus 35.17 10.92 52 183345 6042 90439008
Kaposi's sarcoma 35.09 10.92 13 183384 150 90444900
Klebsiella sepsis 35.08 10.92 29 183368 1752 90443298
Drug-induced liver injury 35.07 10.92 82 183315 90236 90354814
Foetal exposure during pregnancy 35.06 10.92 176 183221 42799 90402251
Substance-induced psychotic disorder 35.05 10.92 36 183361 2876 90442174
Colitis 34.94 10.92 252 183145 69690 90375360
Epistaxis 34.92 10.92 75 183322 85050 90360000
Skin plaque 34.78 10.92 68 183329 9907 90435143
Molluscum contagiosum 34.77 10.92 16 183381 330 90444720
Burkholderia cepacia complex infection 34.72 10.92 14 183383 206 90444844
Granuloma 34.58 10.92 52 183345 6133 90438917
Coeliac disease 34.49 10.92 24 183373 44586 90400464
Chronic hepatitis 34.43 10.92 24 183373 1121 90443929
Apoptosis 34.29 10.92 12 183385 116 90444934
Blood 1,25-dihydroxycholecalciferol increased 34.23 10.92 10 183387 50 90445000
Chronic sinusitis 34.22 10.92 4 183393 23798 90421252
Transplant abscess 34.18 10.92 9 183388 28 90445022
Scleroderma 34.10 10.92 52 183345 6209 90438841
Vasogenic cerebral oedema 34.10 10.92 25 183372 1265 90443785
Presyncope 33.94 10.92 11 183386 31794 90413256
Meningitis bacterial 33.91 10.92 28 183369 1689 90443361
Post herpetic neuralgia 33.80 10.92 34 183363 2650 90442400
Renal artery thrombosis 33.49 10.92 12 183385 125 90444925
Chronic hepatitis C 33.42 10.92 13 183384 173 90444877
Pancreatitis necrotising 33.41 10.92 32 183365 2349 90442701
B-cell lymphoma 33.32 10.92 39 183358 3607 90441443
Renal infarct 33.28 10.92 27 183370 1588 90443462
Demodicidosis 33.28 10.92 7 183390 4 90445046
Pulmonary sepsis 33.24 10.92 31 183366 2200 90442850
Sinus disorder 33.24 10.92 14 183383 34433 90410617
Intrauterine infection 33.24 10.92 12 183385 128 90444922
Cytomegalovirus nephritis 33.22 10.92 8 183389 15 90445035
Crying 32.96 10.92 6 183391 25639 90419411
Blood pressure diastolic decreased 32.95 10.92 7 183390 26819 90418231
Suicidal ideation 32.92 10.92 62 183335 73793 90371257
Hepatic artery aneurysm 32.88 10.92 8 183389 16 90445034
Injection site pain 32.87 10.92 211 183186 173488 90271562
Visual impairment 32.69 10.92 147 183250 132218 90312832
Blood creatine increased 32.62 10.92 54 183343 6913 90438137
Fungaemia 32.57 10.92 37 183360 3313 90441737
Dysgeusia 32.47 10.92 35 183362 52525 90392525
Epilepsy 32.43 10.92 74 183323 82132 90362918
Solid organ transplant rejection 32.43 10.92 9 183388 36 90445014
Skin papilloma 32.43 10.92 48 183349 5582 90439468
Nephrectomy 32.40 10.92 29 183368 1952 90443098
Live birth 32.20 10.92 70 183327 79037 90366013
Viral uveitis 32.20 10.92 12 183385 141 90444909
White blood cell count decreased 32.13 10.92 202 183195 166907 90278143
Acidosis hyperchloraemic 32.04 10.92 21 183376 885 90444165
Respiratory tract congestion 31.98 10.92 8 183389 27402 90417648
Joint injury 31.97 10.92 13 183384 32651 90412399
Pulmonary tuberculosis 31.95 10.92 44 183353 4790 90440260
Peptostreptococcus infection 31.84 10.92 11 183386 102 90444948
Acid fast bacilli infection 31.84 10.92 11 183386 102 90444948
Bacterial endophthalmitis 31.84 10.92 13 183384 198 90444852
Vascular pseudoaneurysm 31.75 10.92 27 183370 1696 90443354
Pneumonia staphylococcal 31.71 10.92 38 183359 3603 90441447
Mycobacterium haemophilum infection 31.66 10.92 13 183384 201 90444849
Orthobunyavirus test positive 31.60 10.92 7 183390 7 90445043
Rebound effect 31.55 10.92 63 183334 9321 90435729
Gastroenteritis 31.54 10.92 130 183267 29099 90415951
Transplantation complication 31.43 10.92 13 183384 205 90444845
Legionella infection 31.38 10.92 17 183380 502 90444548
Splenic vein thrombosis 31.35 10.92 16 183381 417 90444633
Skin lesion 31.17 10.92 154 183243 37211 90407839
Tooth disorder 31.04 10.92 12 183385 31078 90413972
Metabolic acidosis 31 10.92 206 183191 55470 90389580
Osteonecrosis 30.95 10.92 120 183277 26121 90418929
Pancreatitis acute 30.92 10.92 138 183259 31977 90413073
Capillaritis 30.83 10.92 12 183385 160 90444890
Enteritis 30.83 10.92 66 183331 10255 90434795
Toxic leukoencephalopathy 30.72 10.92 20 183377 833 90444217
Bronchial anastomosis complication 30.69 10.92 10 183387 76 90444974
Caesarean section 30.67 10.92 95 183302 18482 90426568
Neoplasm progression 30.52 10.92 27 183370 44459 90400591
Soft tissue sarcoma 30.50 10.92 12 183385 165 90444885
Fat necrosis 30.49 10.92 19 183378 733 90444317
Inflammatory myofibroblastic tumour 30.46 10.92 10 183387 78 90444972
Pseudohypoaldosteronism 30.33 10.92 9 183388 48 90445002
Monocytosis 30.27 10.92 21 183376 973 90444077
Shock 30.27 10.92 127 183270 28651 90416399
Evans syndrome 30.18 10.92 15 183382 369 90444681
Infective scleritis 30.17 10.92 9 183388 49 90445001
Placenta accreta 30.17 10.92 13 183384 228 90444822
Anal squamous cell carcinoma 30.13 10.92 18 183379 643 90444407
Renal atrophy 30.12 10.92 27 183370 1821 90443229
Blood pressure fluctuation 30.11 10.92 37 183360 52376 90392674
Ulcer haemorrhage 30.10 10.92 8 183389 26313 90418737
Ulcerative keratitis 30.01 10.92 36 183361 3417 90441633
Pleocytosis 30.01 10.92 21 183376 987 90444063
Eyelid irritation 30.01 10.92 21 183376 987 90444063
Rheumatoid nodule 29.98 10.92 3 183394 20163 90424887
Diaphragmatic hernia 29.98 10.92 18 183379 649 90444401
Tonsillitis 29.96 10.92 52 183345 6917 90438133
Viral load increased 29.95 10.92 25 183372 1531 90443519
Haemophilus infection 29.91 10.92 24 183373 1390 90443660
Abdominal abscess 29.71 10.92 45 183352 5342 90439708
Speech disorder 29.70 10.92 29 183368 45556 90399494
Cerebral microhaemorrhage 29.66 10.92 13 183384 238 90444812
Cardiac tamponade 29.58 10.92 46 183351 5586 90439464
Coagulopathy 29.53 10.92 109 183288 23180 90421870
Cytokine storm 29.48 10.92 17 183380 568 90444482
Pleomorphism 29.47 10.92 7 183390 12 90445038
Beta-N-acetyl-D-glucosaminidase increased 29.45 10.92 8 183389 29 90445021
Blood beta-D-glucan increased 29.35 10.92 14 183383 314 90444736
Rash pruritic 29.31 10.92 78 183319 82136 90362914
Bronchiolitis obliterans syndrome 29.22 10.92 15 183382 396 90444654
Rhinocerebral mucormycosis 29.15 10.92 19 183378 793 90444257
Acute myeloid leukaemia 29.08 10.92 100 183297 20540 90424510
Acquired plagiocephaly 28.77 10.92 7 183390 14 90445036
Fibromatosis colli of infancy 28.77 10.92 7 183390 14 90445036
Mastitis bacterial 28.76 10.92 9 183388 59 90444991
Myopathy toxic 28.72 10.92 17 183380 597 90444453
Cognitive disorder 28.60 10.92 61 183336 69346 90375704
Abdominal wound dehiscence 28.52 10.92 13 183384 262 90444788
Agitation 28.46 10.92 58 183339 67040 90378010
Disturbance in attention 28.41 10.92 32 183365 47077 90397973
Myocardial necrosis 28.40 10.92 12 183385 200 90444850
Pallor 28.30 10.92 17 183380 34148 90410902
Achromobacter infection 28.26 10.92 9 183388 63 90444987
Inflammatory bowel disease 28.24 10.92 43 183354 5128 90439922
Systemic bacterial infection 28.14 10.92 7 183390 16 90445034
Human herpesvirus 7 infection 28.04 10.92 11 183386 150 90444900
Graft infection 28.03 10.92 13 183384 273 90444777
Chylothorax 27.97 10.92 15 183382 434 90444616
Scleroderma renal crisis 27.87 10.92 15 183382 437 90444613
Acute promyelocytic leukaemia 27.87 10.92 21 183376 1108 90443942
Limb hypoplasia congenital 27.82 10.92 12 183385 211 90444839
Portal vein thrombosis 27.74 10.92 33 183364 3105 90441945
Stress 27.69 10.92 79 183318 81316 90363734
Immune thrombocytopenia 27.67 10.92 74 183323 13252 90431798
Conjunctival melanoma 27.60 10.92 6 183391 5 90445045
Cholangitis infective 27.48 10.92 15 183382 450 90444600
Hypoglycaemia 27.45 10.92 63 183334 69785 90375265
Pruritus 27.33 10.92 861 182536 540664 89904386
Renal amyloidosis 27.32 10.92 13 183384 290 90444760
Cardiac septal defect 27.29 10.92 18 183379 767 90444283
Leiomyosarcoma 27.26 10.92 12 183385 222 90444828
Stomatococcal infection 27.26 10.92 10 183387 112 90444938
Sopor 27.24 10.92 8 183389 24636 90420414
Catatonia 27.10 10.92 46 183351 6010 90439040
Graft versus host disease in eye 27.10 10.92 10 183387 114 90444936
Congenital diaphragmatic hernia 27.07 10.92 12 183385 226 90444824
Porocarcinoma 27.03 10.92 7 183390 20 90445030
Gastrointestinal necrosis 27.01 10.92 33 183364 3192 90441858
Renal haematoma 26.97 10.92 12 183385 228 90444822
Blood albumin increased 26.97 10.92 21 183376 1164 90443886
Respiratory tract infection bacterial 26.94 10.92 15 183382 468 90444582
Swelling face 26.91 10.92 80 183317 81272 90363778
Bullous haemorrhagic dermatosis 26.88 10.92 12 183385 230 90444820
Lupus enteritis 26.79 10.92 9 183388 76 90444974
Complications of intestinal transplant 26.77 10.92 7 183390 21 90445029
Granulicatella bacteraemia 26.77 10.92 7 183390 21 90445029
Intestinal perforation 26.75 10.92 75 183322 13806 90431244
Bacterial colitis 26.62 10.92 11 183386 173 90444877
Removal of renal transplant 26.60 10.92 6 183391 7 90445043
Apoptotic colonopathy 26.58 10.92 9 183388 78 90444972
Acute hepatitis C 26.48 10.92 9 183388 79 90444971
Diabetic macroangiopathy 26.42 10.92 10 183387 123 90444927
Rhesus antigen positive 26.35 10.92 10 183387 124 90444926
Upper respiratory tract infection 26.30 10.92 152 183245 128166 90316884
Liver function test increased 26.27 10.92 86 183311 84769 90360281
Depressed mood 26.26 10.92 38 183359 50184 90394866
Immune recovery uveitis 26.17 10.92 8 183389 48 90445002
Tongue ulceration 26.15 10.92 37 183360 4131 90440919
Gingival hypertrophy 26.12 10.92 27 183370 2173 90442877
Nephrogenic diabetes insipidus 26.09 10.92 19 183378 951 90444099
Muir-Torre syndrome 26.07 10.92 7 183390 24 90445026
Drug level 26.03 10.92 5 183392 0 90445050
Gallbladder rupture 25.86 10.92 15 183382 507 90444543
Cardiac valve abscess 25.81 10.92 9 183388 86 90444964
Balamuthia infection 25.81 10.92 9 183388 86 90444964
Multiple sclerosis 25.79 10.92 12 183385 27828 90417222
Eosinophilic oesophagitis 25.78 10.92 18 183379 843 90444207
Morphoea 25.77 10.92 14 183383 416 90444634
Herpes simplex viraemia 25.77 10.92 14 183383 416 90444634
Squamous cell carcinoma of the vulva 25.76 10.92 8 183389 51 90444999
Mycobacterium kansasii infection 25.72 10.92 10 183387 133 90444917
Acute hepatic failure 25.66 10.92 102 183295 22459 90422591
Hepatocellular carcinoma 25.64 10.92 28 183369 2400 90442650
Aspergillosis oral 25.63 10.92 8 183389 52 90444998
Renal injury 25.58 10.92 61 183336 10182 90434868
Myelitis 25.57 10.92 26 183371 2052 90442998
Listeriosis 25.55 10.92 24 183373 1719 90443331
Sporotrichosis 25.50 10.92 8 183389 53 90444997
Plasmapheresis 25.43 10.92 13 183384 340 90444710
Cerebral infarction 25.39 10.92 114 183283 26482 90418568
Parotitis 25.37 10.92 25 183372 1900 90443150
Renal cell carcinoma 25.37 10.92 35 183362 3816 90441234
Epstein-Barr virus antibody positive 25.36 10.92 13 183384 342 90444708
Transient ischaemic attack 25.31 10.92 30 183367 43146 90401904
Endocarditis staphylococcal 25.26 10.92 14 183383 433 90444617
Ear pain 25.23 10.92 49 183348 57653 90387397
Diffuse large B-cell lymphoma stage IV 25.23 10.92 13 183384 346 90444704
Cholangiocarcinoma 25.21 10.92 21 183376 1282 90443768
Feeling cold 25.19 10.92 12 183385 27453 90417597
Urine output decreased 25.18 10.92 69 183328 12534 90432516
Necrotising fasciitis 25.17 10.92 35 183362 3845 90441205
Endothelial dysfunction 25.17 10.92 11 183386 200 90444850
Pyuria 25.15 10.92 26 183371 2093 90442957
Idiopathic pneumonia syndrome 25.14 10.92 14 183383 437 90444613
Surgical procedure repeated 25.12 10.92 12 183385 270 90444780
Lung infiltration 25.09 10.92 78 183319 15204 90429846
Bone marrow oedema 25.09 10.92 22 183375 1441 90443609
Limb discomfort 25.04 10.92 24 183373 38036 90407014
Pseudallescheria infection 25.00 10.92 6 183391 11 90445039
Transient acantholytic dermatosis 24.93 10.92 9 183388 96 90444954
Oedematous pancreatitis 24.89 10.92 17 183380 768 90444282
Histology abnormal 24.87 10.92 10 183387 146 90444904
Aspergilloma 24.84 10.92 12 183385 277 90444773
Haemorrhagic diathesis 24.78 10.92 42 183355 5482 90439568
Peripheral T-cell lymphoma unspecified 24.76 10.92 12 183385 279 90444771
Muscle twitching 24.73 10.92 9 183388 24193 90420857
Device malfunction 24.71 10.92 6 183391 20971 90424079
Congenital oral malformation 24.63 10.92 11 183386 211 90444839
Volume blood decreased 24.63 10.92 11 183386 211 90444839
Upper respiratory tract infection bacterial 24.63 10.92 10 183387 150 90444900
Weight fluctuation 24.58 10.92 5 183392 19744 90425306
Acquired macroglossia 24.53 10.92 11 183386 213 90444837
Fryns syndrome 24.53 10.92 8 183389 61 90444989
Hepatic infarction 24.50 10.92 16 183381 670 90444380
Dysstasia 24.47 10.92 10 183387 25042 90420008
Dehiscence 24.39 10.92 10 183387 154 90444896
Oropharyngeal pain 24.39 10.92 135 183262 115052 90329998
Gastroenteritis sapovirus 24.34 10.92 6 183391 13 90445037
Renal and pancreas transplant rejection 24.34 10.92 6 183391 13 90445037
Hepatic echinococciasis 24.30 10.92 8 183389 63 90444987
Portal hypertension 24.14 10.92 38 183359 4663 90440387
Measles 24.12 10.92 13 183384 380 90444670
Gastroenteritis adenovirus 24.08 10.92 12 183385 297 90444753
Myopathy 24.08 10.92 71 183326 13447 90431603
Pelvic deformity 23.98 10.92 11 183386 225 90444825
Dyspnoea exertional 23.98 10.92 71 183326 72217 90372833
Microangiopathy 23.97 10.92 23 183374 1692 90443358
Central nervous system necrosis 23.93 10.92 10 183387 162 90444888
Diarrhoea infectious 23.90 10.92 20 183377 1229 90443821
Myelosuppression 23.90 10.92 188 183209 53403 90391647
Enteritis infectious 23.86 10.92 27 183370 2408 90442642
Cutaneous leishmaniasis 23.83 10.92 9 183388 110 90444940
Interleukin level increased 23.76 10.92 16 183381 706 90444344
Viral myositis 23.74 10.92 6 183391 15 90445035
Affect lability 23.71 10.92 4 183393 18059 90426991
Pancreatic leak 23.68 10.92 5 183392 3 90445047
Intentional product misuse 23.66 10.92 97 183300 89507 90355543
Herpes simplex test positive 23.60 10.92 13 183384 397 90444653
Colorectal cancer 23.60 10.92 34 183363 3859 90441191
Tracheobronchitis 23.57 10.92 22 183375 1563 90443487
Pneumoperitoneum 23.54 10.92 23 183374 1730 90443320
Cholangitis acute 23.52 10.92 15 183382 603 90444447
Mental status changes 23.49 10.92 163 183234 44516 90400534
Bone marrow transplant 23.49 10.92 17 183380 843 90444207
Therapy change 23.47 10.92 52 183345 8270 90436780
Panic attack 23.45 10.92 12 183385 26353 90418697
Drug tolerance 23.44 10.92 4 183393 17912 90427138
Tuberculosis 23.40 10.92 67 183330 12482 90432568
Hair follicle tumour benign 23.37 10.92 13 183384 405 90444645
Chronic active Epstein-Barr virus infection 23.33 10.92 7 183390 39 90445011
Papilloedema 23.28 10.92 37 183360 4578 90440472
Neutrophil count decreased 23.19 10.92 71 183326 71461 90373589
Procedural pain 23.18 10.92 20 183377 33340 90411710
Respiratory tract infection fungal 23.14 10.92 14 183383 512 90444538
Renal arteriosclerosis 23.12 10.92 10 183387 177 90444873
Haematuria 23.03 10.92 135 183262 34802 90410248
Reperfusion injury 22.98 10.92 8 183389 76 90444974
Nervousness 22.97 10.92 21 183376 34035 90411015
Restlessness 22.95 10.92 23 183374 35697 90409353
Hepatic angiosarcoma 22.95 10.92 6 183391 18 90445032
Dyslipidaemia 22.91 10.92 58 183339 10049 90435001
Inflammatory pseudotumour 22.90 10.92 7 183390 42 90445008
Skin fissures 22.80 10.92 93 183304 20716 90424334
Avian influenza 22.80 10.92 8 183389 78 90444972
Blood test abnormal 22.79 10.92 7 183390 20945 90424105
Hypophosphataemia 22.73 10.92 74 183323 14780 90430270
Gastrointestinal fungal infection 22.69 10.92 13 183384 429 90444621
Abortion induced 22.68 10.92 64 183333 11824 90433226
Enterobacter pneumonia 22.62 10.92 7 183390 44 90445006
Phaeohyphomycotic brain abscess 22.57 10.92 5 183392 5 90445045
Joint effusion 22.52 10.92 6 183391 19704 90425346
Pustular psoriasis 22.47 10.92 5 183392 18551 90426499
Injection site pruritus 22.44 10.92 47 183350 53787 90391263
Pseudomonal sepsis 22.41 10.92 35 183362 4267 90440783
Orbital apex syndrome 22.36 10.92 7 183390 46 90445004
Mycobacterium fortuitum infection 22.36 10.92 8 183389 83 90444967
Acid base balance abnormal 22.35 10.92 12 183385 348 90444702
Hypocomplementaemia 22.34 10.92 11 183386 265 90444785
HELLP syndrome 22.28 10.92 19 183378 1198 90443852
Localised infection 22.27 10.92 21 183376 33541 90411509
Bone marrow granuloma 22.25 10.92 6 183391 21 90445029
Ventricular remodelling 22.25 10.92 6 183391 21 90445029
Granulomatous rosacea 22.25 10.92 6 183391 21 90445029
Body temperature increased 22.24 10.92 35 183362 44675 90400375
Renal salt-wasting syndrome 22.23 10.92 13 183384 446 90444604
Retinal haemorrhage 22.21 10.92 41 183356 5723 90439327
Arthritis reactive 22.15 10.92 14 183383 554 90444496
Angina pectoris 22.12 10.92 28 183369 39132 90405918
Biliary tract infection fungal 22.09 10.92 5 183392 6 90445044
Capnocytophaga sepsis 22.09 10.92 5 183392 6 90445044
Lacrimal gland enlargement 22.03 10.92 6 183391 22 90445028
Exposure to SARS-CoV-2 22.03 10.92 26 183371 2426 90442624
Lymphadenitis 22.03 10.92 34 183363 4103 90440947
Optic atrophy 21.94 10.92 21 183376 1540 90443510
Hiatus hernia 21.89 10.92 12 183385 25349 90419701
Moraxella infection 21.85 10.92 13 183384 461 90444589
Normochromic normocytic anaemia 21.84 10.92 38 183359 5064 90439986
Pulmonary hypoplasia 21.83 10.92 12 183385 365 90444685
Disseminated coccidioidomycosis 21.81 10.92 9 183388 141 90444909
Infective keratitis 21.74 10.92 7 183390 51 90444999
Anaphylactic reaction 21.73 10.92 97 183300 87427 90357623
Infection 21.73 10.92 562 182835 361532 90083518
Coordination abnormal 21.73 10.92 8 183389 21348 90423702
Chorioretinitis 21.69 10.92 16 183381 817 90444233
Alpha haemolytic streptococcal infection 21.68 10.92 22 183375 1732 90443318
Arteriovenous fistula 21.68 10.92 12 183385 370 90444680
Skin squamous cell carcinoma recurrent 21.66 10.92 5 183392 7 90445043
Thyroid gland abscess 21.66 10.92 5 183392 7 90445043
Vitritis infective 21.62 10.92 6 183391 24 90445026
Bullous erysipelas 21.62 10.92 6 183391 24 90445026
Focal myositis 21.62 10.92 6 183391 24 90445026
Hip fracture 21.60 10.92 21 183376 33056 90411994
Septic pulmonary embolism 21.52 10.92 9 183388 146 90444904
Gastrointestinal viral infection 21.52 10.92 20 183377 1413 90443637
Transitional cell carcinoma 21.30 10.92 15 183382 712 90444338
Monkeypox 21.24 10.92 6 183391 26 90445024
Joint tuberculosis 21.19 10.92 9 183388 152 90444898
Ileectomy 21.17 10.92 11 183386 298 90444752
Arterial rupture 21.11 10.92 12 183385 390 90444660
Sleep disorder due to general medical condition, insomnia type 21.08 10.92 163 183234 128531 90316519
Systemic inflammatory response syndrome 21.02 10.92 43 183354 6473 90438577
Autoimmune hepatitis 21.01 10.92 57 183340 10294 90434756
Bone tuberculosis 21.00 10.92 11 183386 303 90444747
Hypertrichosis 20.98 10.92 20 183377 1459 90443591
Viral vasculitis 20.95 10.92 8 183389 101 90444949
Inappropriate schedule of product administration 20.93 10.92 198 183199 149735 90295315
Herpes simplex reactivation 20.92 10.92 17 183380 1002 90444048
Acidosis 20.91 10.92 65 183332 12671 90432379
Symptom masked 20.90 10.92 17 183380 1004 90444046
Poisoning deliberate 20.88 10.92 4 183393 16482 90428568
Septic encephalopathy 20.88 10.92 9 183388 158 90444892
Sinus congestion 20.88 10.92 15 183382 27409 90417641
Vision blurred 20.85 10.92 134 183263 110159 90334891
Urinary tract infection fungal 20.85 10.92 15 183382 737 90444313
Skin weeping 20.82 10.92 27 183370 2773 90442277
Biliary ischaemia 20.82 10.92 4 183393 0 90445050
Metastases to spleen 20.81 10.92 10 183387 228 90444822
Squamous cell carcinoma of the cervix 20.81 10.92 12 183385 401 90444649
Erythema infectiosum 20.74 10.92 8 183389 104 90444946
Breast cancer 20.72 10.92 49 183348 53712 90391338
Multiple allergies 20.68 10.92 3 183394 15143 90429907
Hepatic vein occlusion 20.64 10.92 7 183390 61 90444989
Neuroleptic malignant syndrome 20.59 10.92 3 183394 15093 90429957
Red blood cell count decreased 20.58 10.92 39 183358 46312 90398738
Anastomotic stenosis 20.57 10.92 12 183385 410 90444640
Viral myelitis 20.54 10.92 6 183391 30 90445020
Eating disorder 20.54 10.92 16 183381 28057 90416993
Perihepatic abscess 20.54 10.92 6 183391 30 90445020
Arterioenteric fistula 20.54 10.92 6 183391 30 90445020
Fungal peritonitis 20.50 10.92 14 183383 632 90444418
Pneumonia necrotising 20.48 10.92 14 183383 633 90444417
Wound sepsis 20.47 10.92 9 183388 166 90444884
Squamous cell carcinoma of the oral cavity 20.46 10.92 12 183385 414 90444636
Herpes zoster meningoencephalitis 20.44 10.92 12 183385 415 90444635
Immunodeficiency 20.43 10.92 35 183362 43199 90401851
Periorbital cellulitis 20.41 10.92 15 183382 762 90444288
Japanese spotted fever 20.38 10.92 6 183391 31 90445019
Papule 20.35 10.92 48 183349 7954 90437096
Urinary retention 20.29 10.92 28 183369 37716 90407334
Tinnitus 20.27 10.92 35 183362 43067 90401983
Drug specific antibody absent 20.27 10.92 8 183389 111 90444939
Hepatitis B reactivation 20.24 10.92 32 183365 3942 90441108
Intervertebral disc degeneration 20.24 10.92 5 183392 17269 90427781
Oral lichen planus 20.17 10.92 15 183382 776 90444274
Maternal exposure during pregnancy 20.11 10.92 906 182491 359157 90085893
Nephrocalcinosis 20.08 10.92 18 183379 1214 90443836
Neuropsychiatric syndrome 20.06 10.92 7 183390 67 90444983
Skin discomfort 20.02 10.92 22 183375 1899 90443151
Endocarditis enterococcal 20.01 10.92 10 183387 249 90444801
Maternal exposure during breast feeding 20.01 10.92 41 183356 6179 90438871
Labelled drug-drug interaction medication error 19.98 10.92 70 183327 14512 90430538
Continuous haemodiafiltration 19.93 10.92 16 183381 927 90444123
Ureteric obstruction 19.93 10.92 23 183374 2095 90442955
Mantle cell lymphoma 19.87 10.92 14 183383 665 90444385
Bone disorder 19.87 10.92 11 183386 23109 90421941
Oral herpes 19.86 10.92 126 183271 33398 90411652
Retrognathia 19.77 10.92 13 183384 551 90444499
Oesophagitis ulcerative 19.75 10.92 15 183382 801 90444249
Transaminases increased 19.74 10.92 136 183261 37056 90407994
Atrial fibrillation 19.71 10.92 174 183223 133437 90311613
Skin hypertrophy 19.69 10.92 30 183367 3580 90441470
Laboratory test abnormal 19.67 10.92 34 183363 41820 90403230
Central nervous system vasculitis 19.67 10.92 17 183380 1092 90443958
Ischaemic nephropathy 19.65 10.92 5 183392 13 90445037
Gastroenteritis Escherichia coli 19.63 10.92 12 183385 447 90444603
Glomerular filtration rate decreased 19.62 10.92 77 183320 16855 90428195
Anaphylactic shock 19.59 10.92 21 183376 31596 90413454
Type 1 diabetes mellitus 19.52 10.92 35 183362 4777 90440273
Nephritis 19.51 10.92 28 183369 3167 90441883
Metastases to lymph nodes 19.51 10.92 60 183337 11629 90433421
Malignant ascites 19.51 10.92 16 183381 956 90444094
Drug trough level 19.49 10.92 6 183391 37 90445013
Lung adenocarcinoma 19.48 10.92 38 183359 5527 90439523
Pericarditis constrictive 19.48 10.92 13 183384 565 90444485
Septal panniculitis 19.44 10.92 7 183390 74 90444976
Cholelithiasis 19.34 10.92 49 183348 52457 90392593
Hypervolaemia 19.33 10.92 123 183274 32634 90412416
Neurofibrosarcoma 19.32 10.92 9 183388 191 90444859
Blood pressure diastolic abnormal 19.31 10.92 8 183389 19873 90425177
Leukocytosis 19.31 10.92 118 183279 30872 90414178
Arteriovenous fistula occlusion 19.28 10.92 11 183386 360 90444690
Upper airway necrosis 19.22 10.92 6 183391 39 90445011
Lymphadenitis bacterial 19.22 10.92 6 183391 39 90445011
Ureterolithiasis 19.21 10.92 23 183374 2179 90442871
Total cholesterol/HDL ratio abnormal 19.20 10.92 7 183390 77 90444973
Red blood cell schistocytes present 19.17 10.92 11 183386 364 90444686
Vaccine virus shedding 19.12 10.92 5 183392 15 90445035
Pancreatic abscess 19.12 10.92 5 183392 15 90445035
Meningoencephalitis viral 19.12 10.92 11 183386 366 90444684
Cutaneous mucormycosis 19.12 10.92 7 183390 78 90444972
Cytotoxic oedema 19.11 10.92 9 183388 196 90444854
Fear 19.11 10.92 5 183392 16617 90428433
Gastrointestinal toxicity 19.09 10.92 52 183345 9415 90435635
Flatulence 19.08 10.92 34 183363 41333 90403717
Infusion site pain 19.08 10.92 8 183389 19730 90425320
Neutrophilic dermatosis 19.07 10.92 10 183387 276 90444774
Product administered to patient of inappropriate age 19.07 10.92 34 183363 4619 90440431
Tracheo-oesophageal fistula 19.03 10.92 14 183383 712 90444338
Potentiating drug interaction 19.02 10.92 38 183359 5624 90439426
Hypoxic-ischaemic encephalopathy 18.99 10.92 34 183363 4634 90440416
Protein urine present 18.98 10.92 43 183354 6941 90438109
Cardiac infection 18.98 10.92 13 183384 590 90444460
Emotional distress 18.91 10.92 28 183369 36634 90408416
Nasal cavity cancer 18.88 10.92 7 183390 81 90444969
Medical device site abscess 18.86 10.92 9 183388 202 90444848
Skin laceration 18.85 10.92 15 183382 26020 90419030
Talipes 18.84 10.92 20 183377 1660 90443390
Abscess 18.81 10.92 82 183315 18809 90426241
Increased insulin requirement 18.80 10.92 7 183390 82 90444968
Growth failure 18.80 10.92 11 183386 378 90444672
Asterixis 18.79 10.92 20 183377 1665 90443385
Injection site warmth 18.79 10.92 6 183391 17509 90427541
Heart transplant 18.78 10.92 13 183384 600 90444450
Limbic encephalitis 18.78 10.92 10 183387 285 90444765
Cardiac disorder 18.76 10.92 56 183341 56816 90388234
Solar lentigo 18.76 10.92 17 183380 1163 90443887
Drug level changed 18.74 10.92 9 183388 205 90444845
Coinfection 18.72 10.92 6 183391 43 90445007
Meningomyelitis herpes 18.72 10.92 6 183391 43 90445007
Radiculopathy 18.71 10.92 7 183390 18498 90426552
Lymphoid tissue hyperplasia 18.70 10.92 9 183388 206 90444844
Mucinous adenocarcinoma of appendix 18.65 10.92 5 183392 17 90445033
Candida pneumonia 18.62 10.92 9 183388 208 90444842
Head discomfort 18.61 10.92 5 183392 16328 90428722
Tendonitis 18.61 10.92 10 183387 21362 90423688
Complications of transplanted pancreas 18.59 10.92 4 183393 3 90445047
Echinococciasis 18.59 10.92 4 183393 3 90445047
Epstein-Barr virus test negative 18.59 10.92 4 183393 3 90445047
Hyperparathyroidism 18.58 10.92 28 183369 3309 90441741
Device related infection 18.55 10.92 102 183295 25684 90419366
Hypertensive encephalopathy 18.54 10.92 14 183383 741 90444309
Osteomalacia 18.52 10.92 15 183382 880 90444170
Wound complication 18.50 10.92 34 183363 4729 90440321
Encephalitis Japanese B 18.48 10.92 6 183391 45 90445005
Chronic inflammatory demyelinating polyradiculoneuropathy 18.47 10.92 16 183381 1031 90444019
Toxic shock syndrome streptococcal 18.44 10.92 10 183387 296 90444754
Rhinorrhoea 18.43 10.92 104 183293 88212 90356838
Skin hyperpigmentation 18.42 10.92 42 183355 6809 90438241
Gastrointestinal stromal tumour 18.41 10.92 18 183379 1355 90443695
Hypoproteinaemia 18.40 10.92 27 183370 3115 90441935
Pneumonia herpes viral 18.37 10.92 6 183391 46 90445004
Osteomyelitis fungal 18.37 10.92 6 183391 46 90445004
Eczema herpeticum 18.31 10.92 9 183388 216 90444834
Blood culture positive 18.20 10.92 35 183362 5037 90440013
Chromaturia 18.19 10.92 8 183389 19179 90425871
Poor quality sleep 18.16 10.92 14 183383 24679 90420371
Urinary incontinence 18.13 10.92 30 183367 37536 90407514
Drug reaction with eosinophilia and systemic symptoms 18.10 10.92 37 183360 42721 90402329
Unevaluable event 18.10 10.92 54 183343 54794 90390256
Acute generalised exanthematous pustulosis 18.06 10.92 3 183394 13700 90431350
Fascioliasis 18.06 10.92 4 183393 4 90445046
Diffuse mesangial sclerosis 18.06 10.92 4 183393 4 90445046
Portal vein embolism 18.01 10.92 7 183390 93 90444957
Sensory loss 18.01 10.92 7 183390 18068 90426982
Pyelocaliectasis 17.99 10.92 14 183383 775 90444275
Normal newborn 17.89 10.92 94 183303 23268 90421782
Arterial thrombosis 17.86 10.92 19 183378 1581 90443469
Amyloidosis 17.85 10.92 17 183380 1239 90443811
Encephalomyelitis 17.84 10.92 8 183389 155 90444895
Febrile neutropenia 17.83 10.92 433 182964 157916 90287134
Cutaneous sporotrichosis 17.82 10.92 5 183392 21 90445029
Blood iron decreased 17.82 10.92 7 183390 17952 90427098
Pneumothorax spontaneous 17.81 10.92 15 183382 930 90444120
Pancreatic pseudoaneurysm 17.81 10.92 7 183390 96 90444954
Oesophageal achalasia 17.78 10.92 13 183384 655 90444395
Post procedural complication 17.72 10.92 81 183316 18961 90426089
Nonspecific reaction 17.71 10.92 25 183372 2784 90442266
Enterococcal sepsis 17.70 10.92 19 183378 1597 90443453
Product complaint 17.69 10.92 3 183394 13497 90431553
Neurocryptococcosis 17.64 10.92 5 183392 22 90445028
Skin induration 17.64 10.92 27 183370 3235 90441815
Sleep apnoea syndrome 17.62 10.92 23 183374 31724 90413326
Pancreatic pseudocyst 17.59 10.92 14 183383 801 90444249
Extranodal marginal zone B-cell lymphoma (MALT type) stage IV 17.59 10.92 4 183393 5 90445045
Lip swelling 17.57 10.92 32 183365 38578 90406472
Lymphoma 17.56 10.92 64 183333 13527 90431523
Meningitis viral 17.55 10.92 19 183378 1613 90443437
Thyroid disorder 17.53 10.92 7 183390 17778 90427272
Mesothelioma malignant 17.52 10.92 6 183391 54 90444996
Temperature regulation disorder 17.51 10.92 4 183393 14575 90430475
Anal pruritus 17.51 10.92 15 183382 952 90444098
Paternal exposure before pregnancy 17.49 10.92 7 183390 101 90444949
Biliary fistula 17.46 10.92 5 183392 23 90445027
Choriomeningitis lymphocytic 17.46 10.92 5 183392 23 90445027
Leukaemia recurrent 17.41 10.92 18 183379 1449 90443601
Salmonellosis 17.41 10.92 17 183380 1278 90443772
B-lymphocyte count decreased 17.39 10.92 18 183379 1451 90443599
Cryptococcal fungaemia 17.36 10.92 7 183390 103 90444947
Intention tremor 17.34 10.92 11 183386 438 90444612
Delusional disorder, erotomanic type 17.33 10.92 6 183391 56 90444994
Joint destruction 17.31 10.92 3 183394 13284 90431766
Malnutrition 17.31 10.92 79 183318 18479 90426571
Leukaemic infiltration extramedullary 17.29 10.92 8 183389 167 90444883
Cerebral artery thrombosis 17.23 10.92 11 183386 443 90444607
Serositis 17.17 10.92 17 183380 1300 90443750
Metastases to lung 17.15 10.92 71 183326 15920 90429130
Labelled drug-drug interaction issue 17.15 10.92 22 183375 2236 90442814
Cytomegalovirus myocarditis 17.14 10.92 6 183391 58 90444992
Blood pressure systolic abnormal 17.13 10.92 9 183388 19469 90425581
Chimerism 17.12 10.92 5 183392 25 90445025
Thyroid tuberculosis 17.12 10.92 5 183392 25 90445025
Asteatosis 17.05 10.92 6 183391 59 90444991
Productive cough 17.04 10.92 89 183308 76974 90368076
Aeromonas infection 17.04 10.92 8 183389 173 90444877
Intestinal pseudo-obstruction 17.02 10.92 16 183381 1147 90443903
Full blood count decreased 17.01 10.92 21 183376 29668 90415382
Glomerulonephropathy 17.00 10.92 7 183390 109 90444941
Arteriovenous fistula thrombosis 16.98 10.92 9 183388 254 90444796
Dermatomyositis 16.97 10.92 27 183370 3343 90441707
Ear neoplasm malignant 16.95 10.92 5 183392 26 90445024
Right ventricle outflow tract obstruction 16.95 10.92 5 183392 26 90445024
Pelvic pain 16.94 10.92 5 183392 15352 90429698
Seasonal allergy 16.94 10.92 13 183384 22970 90422080
Pantoea agglomerans infection 16.88 10.92 6 183391 61 90444989
Folate deficiency 16.83 10.92 26 183371 3139 90441911
Pneumonia respiratory syncytial viral 16.80 10.92 17 183380 1334 90443716
Renal vessel disorder 16.80 10.92 5 183392 27 90445023
Pancreatic pseudocyst haemorrhage 16.79 10.92 4 183393 7 90445043
Desmoplastic melanoma 16.79 10.92 4 183393 7 90445043
Flavobacterium infection 16.79 10.92 4 183393 7 90445043
B-lymphocyte abnormalities 16.76 10.92 9 183388 261 90444789
Failure to thrive 16.76 10.92 46 183351 8365 90436685
Mucosal necrosis 16.72 10.92 7 183390 114 90444936
Hypoacusis 16.70 10.92 19 183378 27831 90417219
Inferior vena caval occlusion 16.65 10.92 5 183392 28 90445022
Pterygium colli 16.65 10.92 5 183392 28 90445022
Adult T-cell lymphoma/leukaemia recurrent 16.65 10.92 5 183392 28 90445022
Cold sweat 16.64 10.92 4 183393 14077 90430973
Hyperoxaluria 16.63 10.92 8 183389 183 90444867
Hepatitis 16.61 10.92 80 183317 70659 90374391
Paraspinal abscess 16.61 10.92 9 183388 266 90444784
Blue toe syndrome 16.54 10.92 11 183386 475 90444575
Abscess limb 16.53 10.92 37 183360 5925 90439125
Blood immunoglobulin M decreased 16.53 10.92 17 183380 1360 90443690
Haptoglobin decreased 16.53 10.92 15 183382 1028 90444022
Coombs positive haemolytic anaemia 16.46 10.92 11 183386 479 90444571
Acute oesophageal mucosal lesion 16.44 10.92 7 183390 119 90444931
Diffuse panbronchiolitis 16.44 10.92 4 183393 8 90445042
Parapox virus infection 16.44 10.92 4 183393 8 90445042
Acarodermatitis 16.44 10.92 17 183380 1369 90443681
Colorectal adenocarcinoma 16.43 10.92 8 183389 188 90444862
Biopsy kidney 16.39 10.92 8 183389 189 90444861
Intestinal tuberculosis 16.39 10.92 7 183390 120 90444930
Nightmare 16.38 10.92 12 183385 21713 90423337
Stem cell transplant 16.38 10.92 21 183376 2133 90442917
Serum ferritin increased 16.36 10.92 42 183355 7339 90437711
Dengue fever 16.35 10.92 14 183383 888 90444162
Postoperative wound infection 16.33 10.92 62 183335 13364 90431686
Clear cell renal cell carcinoma 16.30 10.92 18 183379 1562 90443488
Oropharyngeal candidiasis 16.28 10.92 16 183381 1212 90443838
Injection site haemorrhage 16.26 10.92 20 183377 28298 90416752
Gastrointestinal ulcer 16.24 10.92 24 183373 2787 90442263
Tuberculosis of genitourinary system 16.22 10.92 5 183392 31 90445019
Pancreatic enzyme abnormality 16.22 10.92 5 183392 31 90445019
Purulent pericarditis 16.22 10.92 6 183391 69 90444981
Epileptic encephalopathy 16.21 10.92 10 183387 379 90444671
Abdominal infection 16.16 10.92 22 183375 2368 90442682
Cachexia 16.15 10.92 40 183357 6838 90438212
Haemorrhagic pneumonia 16.12 10.92 4 183393 9 90445041
Abdominal pain 16.10 10.92 646 182751 395075 90049975
Renal cyst infection 16.08 10.92 7 183390 126 90444924
Hepatic neoplasm 16.04 10.92 21 183376 2177 90442873
Hyperparathyroidism secondary 16.02 10.92 19 183378 1782 90443268
Herpes zoster reactivation 16.02 10.92 8 183389 199 90444851
Photosensitivity reaction 16.01 10.92 75 183322 17732 90427318
Wound dehiscence 16.00 10.92 36 183361 5786 90439264
Ophthalmic herpes simplex 15.96 10.92 12 183385 631 90444419
Superinfection viral 15.95 10.92 5 183392 33 90445017
Abdominal compartment syndrome 15.95 10.92 13 183384 770 90444280
Eastern Cooperative Oncology Group performance status 15.93 10.92 7 183390 129 90444921
Head injury 15.91 10.92 24 183373 31164 90413886
Immunoglobulins decreased 15.88 10.92 18 183379 1608 90443442
Toothache 15.85 10.92 13 183384 22217 90422833
Chronic myeloid leukaemia recurrent 15.82 10.92 9 183388 293 90444757
Jejunal ulcer perforation 15.70 10.92 5 183392 35 90445015
Body temperature decreased 15.69 10.92 15 183382 23801 90421249
Lethargy 15.66 10.92 70 183327 63069 90381981
Mycoplasma test positive 15.64 10.92 7 183390 135 90444915
Retroperitoneal haematoma 15.63 10.92 26 183371 3342 90441708
Blood calcium decreased 15.62 10.92 23 183374 30159 90414891
Mesenteric fibrosis 15.62 10.92 3 183394 0 90445050
Renal cell carcinoma stage III 15.62 10.92 3 183394 0 90445050
Pseudoxanthoma elasticum 15.62 10.92 3 183394 0 90445050
Multiple organ transplant rejection 15.62 10.92 3 183394 0 90445050
Anti-HLA antibody test positive 15.62 10.92 3 183394 0 90445050
Disseminated paracoccidioidomycosis 15.62 10.92 3 183394 0 90445050
Herpes sepsis 15.62 10.92 3 183394 0 90445050
Eccrine carcinoma 15.62 10.92 3 183394 0 90445050
Dientamoeba infection 15.62 10.92 3 183394 0 90445050
Cystinosis 15.62 10.92 3 183394 0 90445050
Oropharyngeal lymphoid hyperplasia 15.62 10.92 3 183394 0 90445050
Hepatic steatosis 15.61 10.92 32 183365 36913 90408137
Musculoskeletal chest pain 15.60 10.92 15 183382 23735 90421315
Venous haemorrhage 15.57 10.92 9 183388 302 90444748
Unmasking of previously unidentified disease 15.55 10.92 17 183380 1459 90443591
Eyelid rash 15.50 10.92 10 183387 410 90444640
Throat cancer 15.46 10.92 13 183384 804 90444246
Cerebral ventricle collapse 15.46 10.92 5 183392 37 90445013
Maternal drugs affecting foetus 15.44 10.92 33 183364 5122 90439928
Herpes simplex encephalitis 15.44 10.92 10 183387 413 90444637
Hypertelorism 15.42 10.92 11 183386 533 90444517
Acute pulmonary histoplasmosis 15.41 10.92 7 183390 140 90444910
Tooth infection 15.40 10.92 11 183386 20159 90424891
Erythropoiesis abnormal 15.39 10.92 9 183388 309 90444741
Medical device site cellulitis 15.35 10.92 8 183389 218 90444832
Polyhydramnios 15.34 10.92 22 183375 2486 90442564
Anogenital dysplasia 15.34 10.92 5 183392 38 90445012
Capnocytophaga infection 15.30 10.92 4 183393 12 90445038
Community acquired infection 15.30 10.92 4 183393 12 90445038
Cerebral cavernous malformation 15.30 10.92 4 183393 12 90445038
Renal glycosuria 15.30 10.92 4 183393 12 90445038
Dermatitis papillaris capillitii 15.30 10.92 4 183393 12 90445038
Pneumonia haemophilus 15.30 10.92 17 183380 1486 90443564
Ileocaecal resection 15.28 10.92 11 183386 541 90444509
Adenocarcinoma 15.27 10.92 25 183372 3171 90441879
Product prescribing issue 15.27 10.92 43 183354 7936 90437114
Hepatic infection bacterial 15.23 10.92 5 183392 39 90445011
Neurological symptom 15.22 10.92 39 183358 6808 90438242
Spinal osteoarthritis 15.21 10.92 10 183387 19138 90425912
Blood glucose decreased 15.15 10.92 15 183382 23414 90421636
Hirsutism 15.14 10.92 18 183379 1692 90443358
Arthritis bacterial 15.12 10.92 41 183356 7404 90437646
Biliary tract infection 15.09 10.92 13 183384 831 90444219
Choking 15.07 10.92 3 183394 12030 90433020
Fungal abscess central nervous system 15.06 10.92 4 183393 13 90445037
Acute allograft nephropathy 15.06 10.92 4 183393 13 90445037
H3N2 influenza 15.06 10.92 4 183393 13 90445037
Delusional disorder, persecutory type 15.05 10.92 9 183388 322 90444728
Pyoderma gangrenosum 15.04 10.92 30 183367 4434 90440616
Pupil fixed 15.02 10.92 20 183377 2108 90442942
Combined immunodeficiency 15.01 10.92 7 183390 149 90444901
Cervicitis 15.00 10.92 11 183386 557 90444493
Milk allergy 14.98 10.92 10 183387 435 90444615
Small intestinal perforation 14.97 10.92 19 183378 1910 90443140
Pneumopericardium 14.96 10.92 6 183391 87 90444963
Body height decreased 14.92 10.92 3 183394 11946 90433104
Upper limb fracture 14.92 10.92 13 183384 21565 90423485
Clostridial sepsis 14.91 10.92 11 183386 562 90444488
Myocardial calcification 14.90 10.92 8 183389 232 90444818
Brucellosis 14.90 10.92 6 183391 88 90444962
Hypomagnesaemia 14.86 10.92 123 183274 35465 90409585
Anastomotic complication 14.85 10.92 9 183388 330 90444720
Hypersomnia 14.85 10.92 13 183384 21518 90423532
Breast cancer metastatic 14.84 10.92 6 183391 15126 90429924
Diffuse large B-cell lymphoma stage I 14.83 10.92 4 183393 14 90445036
Tumour lysis syndrome 14.82 10.92 53 183344 11099 90433951
Hemianopia homonymous 14.82 10.92 13 183384 852 90444198
Renal-limited thrombotic microangiopathy 14.81 10.92 8 183389 235 90444815
Norovirus test positive 14.81 10.92 8 183389 235 90444815
Acute motor axonal neuropathy 14.80 10.92 5 183392 43 90445007
Imprisonment 14.78 10.92 9 183388 333 90444717
Ageusia 14.78 10.92 7 183390 16069 90428981
Electrocardiogram QT prolonged 14.75 10.92 86 183311 72370 90372680
Hypertension 14.74 10.92 766 182631 456766 89988284
Herpes simplex pneumonia 14.72 10.92 6 183391 91 90444959
Odynophagia 14.70 10.92 46 183351 8997 90436053
Haemorrhagic ovarian cyst 14.66 10.92 12 183385 715 90444335
Cholestasis of pregnancy 14.63 10.92 17 183380 1560 90443490
Oesophageal squamous cell carcinoma stage IV 14.62 10.92 4 183393 15 90445035
Disseminated varicella 14.62 10.92 4 183393 15 90445035
Hepatic cirrhosis 14.58 10.92 72 183325 63181 90381869
Traumatic haemothorax 14.56 10.92 8 183389 243 90444807
Cardiogenic shock 14.52 10.92 92 183305 24376 90420674
Thymus enlargement 14.51 10.92 7 183390 161 90444889
Lung consolidation 14.51 10.92 31 183366 4809 90440241
Pulmonary cavitation 14.51 10.92 14 183383 1037 90444013
Peripheral coldness 14.48 10.92 5 183392 13887 90431163
Arterial disorder 14.48 10.92 16 183381 1390 90443660
Toxic optic neuropathy 14.47 10.92 8 183389 246 90444804
Injection site mass 14.45 10.92 14 183383 22076 90422974
Organ failure 14.45 10.92 24 183373 3081 90441969
Genitourinary tract infection 14.45 10.92 8 183389 247 90444803
Tonsillar exudate 14.41 10.92 4 183393 16 90445034
Rebound atopic dermatitis 14.40 10.92 17 183380 1587 90443463
Fibrosis 14.38 10.92 35 183362 5917 90439133
Wound infection fungal 14.36 10.92 7 183390 165 90444885
Pelvic infection 14.36 10.92 9 183388 351 90444699
Cerebral mass effect 14.34 10.92 14 183383 1052 90443998
Oesophagitis 14.32 10.92 71 183326 17178 90427872
Beta 2 microglobulin urine increased 14.32 10.92 5 183392 48 90445002
Autoimmune pancytopenia 14.31 10.92 6 183391 98 90444952
Cytomegalovirus syndrome 14.31 10.92 6 183391 98 90444952
Cleft lip and palate 14.25 10.92 12 183385 744 90444306
Epstein-Barr virus antigen positive 14.23 10.92 5 183392 49 90445001
Periportal oedema 14.23 10.92 5 183392 49 90445001
Lymphocytopenia neonatal 14.22 10.92 4 183393 17 90445033
Peritoneal dialysis 14.21 10.92 10 183387 474 90444576
Aortic rupture 14.20 10.92 6 183391 100 90444950
C3 glomerulopathy 14.17 10.92 7 183390 170 90444880
Metastases to pleura 14.11 10.92 19 183378 2025 90443025
Visual field defect 14.09 10.92 39 183358 7127 90437923
Tuberculoma of central nervous system 14.08 10.92 9 183388 363 90444687
Preterm premature rupture of membranes 14.08 10.92 17 183380 1624 90443426
Coarctation of the aorta 14.07 10.92 11 183386 613 90444437
Portal vein flow decreased 14.04 10.92 4 183393 18 90445032
Mouth ulceration 14.03 10.92 133 183264 39841 90405209
Acute motor-sensory axonal neuropathy 14.02 10.92 9 183388 366 90444684
Blood parathyroid hormone increased 13.94 10.92 25 183372 3412 90441638
Arteriosclerosis 13.93 10.92 51 183346 10802 90434248
Lower respiratory tract infection fungal 13.91 10.92 8 183389 266 90444784
Immune-mediated cytopenia 13.88 10.92 6 183391 106 90444944
Splenic marginal zone lymphoma 13.88 10.92 5 183392 53 90444997
Retinal degeneration 13.88 10.92 14 183383 1095 90443955
Skin squamous cell carcinoma metastatic 13.86 10.92 4 183393 19 90445031
Malignant anorectal neoplasm 13.86 10.92 4 183393 19 90445031
Restless legs syndrome 13.84 10.92 15 183382 22455 90422595
Acinetobacter bacteraemia 13.83 10.92 6 183391 107 90444943
Renal cell carcinoma stage I 13.79 10.92 5 183392 54 90444996
Premature rupture of membranes 13.77 10.92 33 183364 5525 90439525
Blood alkaline phosphatase 13.77 10.92 7 183390 181 90444869
Hypertransaminasaemia 13.76 10.92 66 183331 15759 90429291
Craniofacial deformity 13.73 10.92 7 183390 182 90444868
Ischaemia 13.73 10.92 32 183365 5263 90439787
Hypothyroidism 13.72 10.92 58 183339 53069 90391981
Acute myeloid leukaemia (in remission) 13.69 10.92 4 183393 20 90445030
Hepatic amoebiasis 13.69 10.92 4 183393 20 90445030
Left ventricular hypertrophy 13.66 10.92 35 183362 6109 90438941
Large intestine perforation 13.64 10.92 47 183350 9665 90435385
Parvovirus B19 test positive 13.63 10.92 6 183391 111 90444939
Gastrointestinal pain 13.61 10.92 3 183394 11203 90433847
Haematemesis 13.59 10.92 30 183367 33696 90411354
Paraneoplastic pemphigus 13.58 10.92 6 183391 112 90444938
Neutrophilic panniculitis 13.55 10.92 5 183392 57 90444993
Lymphorrhoea 13.55 10.92 5 183392 57 90444993
Conjunctival neoplasm 13.54 10.92 3 183394 3 90445047
Anion gap normal 13.54 10.92 3 183394 3 90445047
Retroviral infection 13.54 10.92 3 183394 3 90445047
Vitamin E deficiency 13.54 10.92 3 183394 3 90445047
Acute vestibular syndrome 13.53 10.92 4 183393 21 90445029
Metabolic encephalopathy 13.52 10.92 37 183360 6715 90438335
Splenic infarction 13.52 10.92 19 183378 2108 90442942
Sepsis syndrome 13.51 10.92 13 183384 960 90444090
Jejunal ulcer 13.49 10.92 6 183391 114 90444936
Adenocarcinoma of colon 13.48 10.92 22 183375 2784 90442266
Troponin increased 13.47 10.92 5 183392 13276 90431774
Metastases to spinal cord 13.46 10.92 8 183389 283 90444767
Vaccination site inflammation 13.40 10.92 5 183392 59 90444991
Femur fracture 13.38 10.92 48 183349 46034 90399016
Tuberculosis liver 13.38 10.92 4 183393 22 90445028
Pneumonia serratia 13.38 10.92 4 183393 22 90445028
Autoinflammatory disease 13.36 10.92 8 183389 287 90444763
Hypogonadism 13.34 10.92 6 183391 117 90444933
Enterobacter bacteraemia 13.33 10.92 12 183385 814 90444236
Chronic recurrent multifocal osteomyelitis 13.32 10.92 5 183392 60 90444990
Fanconi syndrome 13.32 10.92 18 183379 1925 90443125
Injection site swelling 13.29 10.92 69 183328 59770 90385280
Otitis externa 13.26 10.92 18 183379 1933 90443117
IIIrd nerve paralysis 13.25 10.92 12 183385 820 90444230
Sputum discoloured 13.25 10.92 13 183384 20378 90424672
Bronchoalveolar lavage abnormal 13.23 10.92 7 183390 197 90444853
Microgenia 13.23 10.92 4 183393 23 90445027
Blood urea increased 13.18 10.92 106 183291 30307 90414743
Respiratory tract infection viral 13.18 10.92 23 183374 3073 90441977
Vascular graft thrombosis 13.17 10.92 5 183392 62 90444988
Diverticulitis 13.17 10.92 47 183350 45140 90399910
Aggression 13.15 10.92 21 183376 26647 90418403
Mycetoma mycotic 13.09 10.92 4 183393 24 90445026
Complement fixation abnormal 13.08 10.92 3 183394 4 90445046
Therapeutic product ineffective 13.08 10.92 20 183377 2394 90442656
Rotator cuff syndrome 13.07 10.92 8 183389 15911 90429139
Exposure via partner 13.07 10.92 6 183391 123 90444927
Keratitis fungal 13.07 10.92 7 183390 202 90444848
Mutism 13.07 10.92 17 183380 1752 90443298
Hallucination 13.05 10.92 79 183318 65880 90379170
Arrhythmia 13.03 10.92 43 183354 42289 90402761
Gastroenteritis bacterial 13.03 10.92 9 183388 414 90444636
Pulmonary oedema 13.03 10.92 187 183210 61893 90383157
Rash maculo-papular 13.00 10.92 41 183356 40892 90404158
Genital candidiasis 12.97 10.92 7 183390 205 90444845
Pemphigoid 12.95 10.92 44 183353 8982 90436068
Anti-interferon antibody positive 12.95 10.92 4 183393 25 90445025
Lung abscess 12.94 10.92 19 183378 2194 90442856
Incorrect product administration duration 12.93 10.92 12 183385 19310 90425740
Throat tightness 12.92 10.92 25 183372 29459 90415591
Needle issue 12.91 10.92 6 183391 13928 90431122
Hypertensive emergency 12.91 10.92 19 183378 2198 90442852
Escherichia test positive 12.91 10.92 21 183376 2649 90442401
Procedural failure 12.89 10.92 5 183392 66 90444984
Bacteroides infection 12.88 10.92 8 183389 307 90444743
Chronic cutaneous lupus erythematosus 12.84 10.92 12 183385 854 90444196
Tonsil cancer 12.83 10.92 8 183389 309 90444741
Anastomotic haemorrhage 12.82 10.92 5 183392 67 90444983
Leiomyosarcoma metastatic 12.81 10.92 4 183393 26 90445024
Herpes simplex meningoencephalitis 12.81 10.92 4 183393 26 90445024
Small cell lung cancer recurrent 12.81 10.92 4 183393 26 90445024
Herpes virus infection 12.80 10.92 35 183362 6349 90438701
Granulomatous dermatitis 12.79 10.92 7 183390 211 90444839
Venous thrombosis 12.79 10.92 32 183365 5505 90439545
Jarisch-Herxheimer reaction 12.79 10.92 9 183388 427 90444623
Extranodal marginal zone B-cell lymphoma (MALT type) 12.77 10.92 10 183387 559 90444491
Nervous system disorder 12.69 10.92 81 183316 21512 90423538
Herpes simplex meningitis 12.69 10.92 5 183392 69 90444981
Hepatitis infectious mononucleosis 12.68 10.92 6 183391 132 90444918
Hepatobiliary infection 12.68 10.92 4 183393 27 90445023
Portal vein stenosis 12.68 10.92 3 183394 5 90445045
Spinal stenosis 12.66 10.92 10 183387 17414 90427636
Acute lymphocytic leukaemia recurrent 12.62 10.92 21 183376 2700 90442350
Erosive oesophagitis 12.61 10.92 17 183380 1814 90443236
Blood stem cell transplant failure 12.58 10.92 7 183390 218 90444832
Paroxysmal nocturnal haemoglobinuria 12.58 10.92 8 183389 320 90444730
Mood swings 12.55 10.92 14 183383 20688 90424362
Pneumococcal infection 12.53 10.92 14 183383 1231 90443819
Spinal disorder 12.53 10.92 4 183393 11675 90433375
Periumbilical abscess 12.53 10.92 7 183390 220 90444830
Abscess fungal 12.50 10.92 5 183392 72 90444978
Oesophageal squamous cell carcinoma 12.48 10.92 6 183391 137 90444913
Ichthyosis 12.44 10.92 5 183392 73 90444977
Abdominal wall abscess 12.42 10.92 13 183384 1062 90443988
Skin infection 12.41 10.92 70 183327 17794 90427256
Agnosia 12.40 10.92 6 183391 139 90444911
Infectious thyroiditis 12.37 10.92 5 183392 74 90444976
Blindness cortical 12.37 10.92 10 183387 585 90444465
Intracranial pressure increased 12.35 10.92 36 183361 6775 90438275
Infective thrombosis 12.33 10.92 3 183394 6 90445044
Iliac artery perforation 12.33 10.92 3 183394 6 90445044
Encephalitis protozoal 12.33 10.92 3 183394 6 90445044
Bartonella test positive 12.33 10.92 3 183394 6 90445044
Hepatitis C virus test 12.33 10.92 3 183394 6 90445044
Vulvovaginal warts 12.33 10.92 3 183394 6 90445044
Emphysematous cholecystitis 12.33 10.92 3 183394 6 90445044
Benign familial haematuria 12.33 10.92 3 183394 6 90445044
Meningitis aspergillus 12.33 10.92 3 183394 6 90445044
Keratoacanthoma 12.31 10.92 10 183387 589 90444461
Therapy non-responder 12.28 10.92 363 183034 136341 90308709
Renal phospholipidosis 12.27 10.92 7 183390 229 90444821
Hypercreatininaemia 12.27 10.92 11 183386 742 90444308
Mucosal inflammation 12.26 10.92 174 183223 57451 90387599
Skin cancer 12.20 10.92 57 183340 13462 90431588
Blood immunoglobulin G decreased 12.19 10.92 24 183373 3514 90441536
Mass 12.15 10.92 63 183334 15514 90429536
Dilatation intrahepatic duct acquired 12.08 10.92 11 183386 757 90444293
Palmar-plantar erythrodysaesthesia syndrome 12.07 10.92 24 183373 27999 90417051
Heart rate irregular 12.07 10.92 19 183378 24249 90420801
Peritonitis bacterial 12.06 10.92 30 183367 5141 90439909
Biopsy heart abnormal 12.02 10.92 3 183394 7 90445043
Keratitis viral 12.02 10.92 3 183394 7 90445043
Loose associations 12.02 10.92 3 183394 7 90445043
Foetal distress syndrome 12.00 10.92 16 183381 1689 90443361
Biopsy kidney abnormal 11.99 10.92 4 183393 33 90445017
Wound necrosis 11.93 10.92 9 183388 476 90444574
Foetal hypokinesia 11.91 10.92 10 183387 617 90444433
Intestinal villi atrophy 11.90 10.92 8 183389 352 90444698
Gingivitis ulcerative 11.90 10.92 7 183390 243 90444807
Hepatic vein stenosis 11.88 10.92 4 183393 34 90445016
Tonic clonic movements 11.87 10.92 16 183381 1706 90443344
Osteomyelitis bacterial 11.87 10.92 7 183390 244 90444806
Partial seizures 11.87 10.92 37 183360 7223 90437827
Mesangioproliferative glomerulonephritis 11.85 10.92 5 183392 83 90444967
Cervix carcinoma stage IV 11.85 10.92 5 183392 83 90444967
Musculoskeletal disorder 11.85 10.92 16 183381 21753 90423297
Status epilepticus 11.85 10.92 72 183325 18802 90426248
Reticulocytosis 11.82 10.92 7 183390 246 90444804
Spondylitis 11.82 10.92 7 183390 14171 90430879
Lacrimation increased 11.81 10.92 23 183374 27039 90418011
Necrotising soft tissue infection 11.77 10.92 7 183390 248 90444802
Catheter site abscess 11.77 10.92 7 183390 248 90444802
Scopulariopsis infection 11.73 10.92 3 183394 8 90445042
Leiomyoma 11.70 10.92 9 183388 490 90444560
Eye infection fungal 11.67 10.92 6 183391 159 90444891
Gastric disorder 11.65 10.92 32 183365 33352 90411698
Mental impairment 11.65 10.92 10 183387 16710 90428340
Multi-organ disorder 11.60 10.92 18 183379 2182 90442868
Glomerulonephritis proliferative 11.59 10.92 7 183390 255 90444795
Blood creatine phosphokinase increased 11.58 10.92 33 183364 33990 90411060
Bronchiolitis 11.58 10.92 23 183374 3389 90441661
Hypercalcaemia 11.56 10.92 113 183284 34127 90410923
Concussion 11.55 10.92 4 183393 11087 90433963
Fibrin degradation products increased 11.53 10.92 6 183391 163 90444887
Cardiac valve vegetation 11.53 10.92 8 183389 371 90444679
Glucose tolerance impaired 11.52 10.92 39 183358 7946 90437104
Nephrosclerosis 11.52 10.92 13 183384 1156 90443894
Skin tightness 11.50 10.92 27 183370 4461 90440589
Spinal cord disorder 11.50 10.92 15 183382 1550 90443500
Renal tubular dysfunction 11.48 10.92 9 183388 504 90444546
Lymphadenitis fungal 11.47 10.92 3 183394 9 90445041
Ureteral stent removal 11.47 10.92 3 183394 9 90445041
Acquired mitochondrial DNA mutation 11.47 10.92 3 183394 9 90445041
Blood lactate dehydrogenase 11.47 10.92 3 183394 9 90445041
Bile duct necrosis 11.47 10.92 3 183394 9 90445041
Compulsive handwashing 11.47 10.92 3 183394 9 90445041
Pharyngeal necrosis 11.47 10.92 3 183394 9 90445041
Cryptococcal meningoencephalitis 11.46 10.92 6 183391 165 90444885
Blast crisis in myelogenous leukaemia 11.46 10.92 10 183387 651 90444399
Cardiac hypertrophy 11.44 10.92 13 183384 1165 90443885
Gastroenteritis viral 11.43 10.92 28 183369 30327 90414723
Temperature intolerance 11.43 10.92 5 183392 12025 90433025
Salmonella bacteraemia 11.43 10.92 6 183391 166 90444884
Haemostasis 11.43 10.92 8 183389 376 90444674
Hyperammonaemic encephalopathy 11.42 10.92 20 183377 2679 90442371
Renal tuberculosis 11.40 10.92 4 183393 39 90445011
Limbal stem cell deficiency 11.40 10.92 4 183393 39 90445011
Pancreatitis relapsing 11.40 10.92 14 183383 1362 90443688
Mesenteric abscess 11.38 10.92 5 183392 92 90444958
Meningoencephalitis bacterial 11.38 10.92 7 183390 264 90444786
Campylobacter gastroenteritis 11.36 10.92 11 183386 818 90444232
Pneumothorax 11.33 10.92 72 183325 19095 90425955
Amniotic fluid index decreased 11.31 10.92 4 183393 40 90445010
Anomaly of external ear congenital 11.30 10.92 6 183391 170 90444880
Hypothermia 11.24 10.92 9 183388 15566 90429484
Vaginal dysplasia 11.24 10.92 5 183392 95 90444955
Nasal septum ulceration 11.24 10.92 3 183394 10 90445040
Hepatic artery occlusion 11.24 10.92 3 183394 10 90445040
Antithrombin III deficiency 11.24 10.92 3 183394 10 90445040
Amniotic cavity infection 11.23 10.92 14 183383 1382 90443668
Methaemoglobinaemia 11.22 10.92 25 183372 3990 90441060
Focal peritonitis 11.22 10.92 4 183393 41 90445009
Gastrointestinal vascular malformation 11.22 10.92 4 183393 41 90445009
Apgar score low 11.21 10.92 13 183384 1190 90443860
Increased tendency to bruise 11.21 10.92 5 183392 11885 90433165
Eructation 11.20 10.92 4 183393 10878 90434172
Acinetobacter test positive 11.19 10.92 5 183392 96 90444954
Nodular regenerative hyperplasia 11.17 10.92 10 183387 673 90444377
Anger 11.12 10.92 7 183390 13713 90431337
Mucocutaneous leishmaniasis 11.12 10.92 8 183389 393 90444657
Mucosal toxicity 11.10 10.92 8 183389 394 90444656
Cutaneous T-cell lymphoma 11.09 10.92 15 183382 1605 90443445
Hepatosplenomegaly 11.09 10.92 21 183376 2988 90442062
Rib fracture 11.08 10.92 23 183374 26412 90418638
Leukocyturia 11.08 10.92 15 183382 1607 90443443
Hepatic haematoma 11.07 10.92 9 183388 531 90444519
Metastatic malignant melanoma 11.06 10.92 15 183382 1609 90443441
Urinoma 11.05 10.92 4 183393 43 90445007
Muscle abscess 11.03 10.92 8 183389 398 90444652
Eye inflammation 11.03 10.92 38 183359 7813 90437237
Sarcoma metastatic 11.02 10.92 3 183394 11 90445039
Renal cell carcinoma recurrent 11.02 10.92 3 183394 11 90445039
Increased appetite 11.01 10.92 5 183392 11760 90433290
Lupus pneumonitis 11.00 10.92 5 183392 100 90444950
Carotid artery aneurysm 10.98 10.92 8 183389 401 90444649
Biopsy liver abnormal 10.96 10.92 7 183390 282 90444768
Gingival ulceration 10.96 10.92 12 183385 1032 90444018
Anal incontinence 10.95 10.92 10 183387 16220 90428830
Neuropsychiatric symptoms 10.95 10.92 10 183387 691 90444359
Angiopathy 10.95 10.92 30 183367 5450 90439600
Feeling jittery 10.95 10.92 9 183388 15362 90429688
Lichen planus 10.94 10.92 20 183377 2771 90442279

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 4314.36 11.46 1891 230749 11697 42376998
Cytomegalovirus infection 2830.50 11.46 1913 230727 30393 42358302
Post transplant lymphoproliferative disorder 2793.31 11.46 1238 231402 7882 42380813
Immunosuppressant drug level increased 2557.52 11.46 1108 231532 6623 42382072
Polyomavirus-associated nephropathy 2389.44 11.46 963 231677 4652 42384043
Thrombotic microangiopathy 1807.14 11.46 1081 231559 13701 42374994
Kidney transplant rejection 1617.91 11.46 838 231802 7845 42380850
Cytomegalovirus viraemia 1477.77 11.46 838 231802 9539 42379156
Complications of transplanted kidney 1384.40 11.46 646 231994 4704 42383991
Nocardiosis 1291.51 11.46 610 232030 4580 42384115
BK virus infection 1209.49 11.46 694 231946 8090 42380605
Acute graft versus host disease 1051.43 11.46 619 232021 7596 42381099
Liver transplant rejection 1048.31 11.46 425 232215 2088 42386607
Transplant dysfunction 1043.19 11.46 460 232180 2883 42385812
Graft versus host disease 1042.63 11.46 728 231912 12197 42376498
Aspergillus infection 1023.33 11.46 780 231860 15057 42373638
Epstein-Barr virus infection 967.93 11.46 624 232016 9094 42379601
Drug interaction 875.87 11.46 3317 229323 263682 42125013
Drug level increased 857.70 11.46 877 231763 25323 42363372
COVID-19 832.82 11.46 1907 230733 114041 42274654
Mucormycosis 804.92 11.46 496 232144 6647 42382048
Fatigue 800.03 11.46 723 231917 434918 41953777
Product use in unapproved indication 790.89 11.46 2506 230134 181950 42206745
Bronchopulmonary aspergillosis 785.16 11.46 730 231910 18699 42369996
Adenovirus infection 755.05 11.46 468 232172 6341 42382354
Polyomavirus viraemia 741.99 11.46 316 232324 1796 42386899
Phaeohyphomycosis 725.74 11.46 265 232375 919 42387776
Nephropathy toxic 721.95 11.46 654 231986 16184 42372511
Parvovirus B19 infection 715.53 11.46 291 232349 1443 42387252
Chronic graft versus host disease 662.72 11.46 412 232228 5613 42383082
Graft versus host disease in skin 649.31 11.46 386 232254 4826 42383869
Acute graft versus host disease in skin 647.85 11.46 439 232201 6985 42381710
Transplant failure 636.79 11.46 349 232291 3695 42385000
Dizziness 635.65 11.46 283 232357 248971 42139724
Pulmonary nocardiosis 626.28 11.46 268 232372 1544 42387151
Fall 622.43 11.46 251 232389 234269 42154426
Chronic allograft nephropathy 611.20 11.46 254 232386 1344 42387351
Malacoplakia 600.69 11.46 216 232424 708 42387987
Posterior reversible encephalopathy syndrome 591.33 11.46 519 232121 12302 42376393
Renal transplant failure 581.64 11.46 241 232399 1264 42387431
Enterococcal infection 576.72 11.46 498 232142 11541 42377154
Dyspnoea 573.62 11.46 961 231679 441660 41947035
Cytomegalovirus infection reactivation 573.55 11.46 481 232159 10697 42377998
Off label use 564.96 11.46 5628 227012 632707 41755988
Immunosuppressant drug level decreased 556.25 11.46 247 232393 1577 42387118
Cryptococcosis 552.73 11.46 294 232346 2917 42385778
Pneumocystis jirovecii pneumonia 543.71 11.46 679 231961 24502 42364193
Drug abuse 539.22 11.46 6 232634 104765 42283930
Renal impairment 523.25 11.46 1553 231087 108675 42280020
Pseudomonas infection 515.56 11.46 530 232110 15393 42373302
Delayed graft function 507.12 11.46 260 232380 2375 42386320
Multiple organ dysfunction syndrome 499.94 11.46 1408 231232 95627 42293068
Pain 495.87 11.46 368 232272 244480 42144215
Brain abscess 494.19 11.46 302 232338 3982 42384713
Klebsiella infection 487.41 11.46 441 232199 10891 42377804
Focal segmental glomerulosclerosis 474.75 11.46 246 232394 2302 42386393
Human herpesvirus 8 infection 473.54 11.46 208 232432 1289 42387406
Kidney fibrosis 467.89 11.46 249 232391 2473 42386222
Escherichia infection 461.92 11.46 429 232211 10967 42377728
Hepatitis E 459.32 11.46 258 232382 2876 42385819
Graft versus host disease in gastrointestinal tract 458.00 11.46 308 232332 4835 42383860
Meningitis cryptococcal 448.15 11.46 258 232382 3025 42385670
Completed suicide 444.97 11.46 19 232621 96446 42292249
Acute respiratory distress syndrome 443.53 11.46 675 231965 29433 42359262
Constipation 428.12 11.46 175 232465 162116 42226579
Nausea 414.94 11.46 976 231664 395823 41992872
Strongyloidiasis 414.12 11.46 249 232391 3182 42385513
Acute kidney injury 412.36 11.46 3414 229226 363923 42024772
Septic shock 410.82 11.46 1266 231374 90406 42298289
Heart transplant rejection 383.74 11.46 181 232459 1353 42387342
Infection reactivation 383.61 11.46 203 232437 1991 42386704
Asthenia 370.90 11.46 601 232039 280192 42108503
Haemophagocytic lymphohistiocytosis 369.02 11.46 476 232164 17746 42370949
Blastomycosis 367.25 11.46 140 232500 564 42388131
Alternaria infection 361.23 11.46 133 232507 475 42388220
Fungal infection 357.54 11.46 488 232152 19234 42369461
Epstein-Barr viraemia 353.38 11.46 195 232445 2094 42386601
Somnolence 353.31 11.46 164 232476 140941 42247754
Diffuse large B-cell lymphoma 352.81 11.46 340 232300 9114 42379581
Renal tubular atrophy 352.70 11.46 168 232472 1287 42387408
Cytomegalovirus colitis 351.12 11.46 237 232403 3744 42384951
Malignant neoplasm progression 346.21 11.46 83 232557 108317 42280378
Arthralgia 341.58 11.46 370 232270 204868 42183827
Renal tubular injury 332.15 11.46 172 232468 1607 42387088
Anxiety 330.63 11.46 117 232523 118443 42270252
Rash 318.10 11.46 646 231994 276308 42112387
Hypotension 314.92 11.46 579 232061 257052 42131643
Cryptosporidiosis infection 314.21 11.46 129 232511 658 42388037
Lung transplant rejection 313.55 11.46 140 232500 907 42387788
Scedosporium infection 312.24 11.46 158 232482 1400 42387295
Neurotoxicity 310.50 11.46 503 232137 23148 42365547
Pneumatosis intestinalis 308.94 11.46 235 232405 4517 42384178
West Nile viral infection 304.99 11.46 132 232508 785 42387910
Drug hypersensitivity 302.26 11.46 84 232556 99305 42289390
JC virus infection 301.80 11.46 194 232446 2810 42385885
Varicella zoster virus infection 301.65 11.46 184 232456 2417 42386278
Acute graft versus host disease in intestine 301.05 11.46 215 232425 3736 42384959
Pain in extremity 299.84 11.46 230 232410 150374 42238321
Leukopenia 298.10 11.46 992 231648 73754 42314941
Product dose omission issue 295.72 11.46 245 232395 154120 42234575
Cytomegalovirus test positive 290.56 11.46 218 232422 4101 42384594
Malaise 288.52 11.46 445 232195 211711 42176984
Myocardial infarction 285.24 11.46 161 232479 123848 42264847
Epstein-Barr virus associated lymphoproliferative disorder 283.78 11.46 173 232467 2270 42386425
Post transplant distal limb syndrome 282.75 11.46 103 232537 354 42388341
Histoplasmosis disseminated 276.57 11.46 161 232479 1930 42386765
Chronic graft versus host disease in skin 276.28 11.46 147 232493 1459 42387236
Respiratory failure 276.28 11.46 1406 231234 126726 42261969
Pneumonia cytomegaloviral 274.78 11.46 207 232433 3919 42384776
Hepatitis C 274.62 11.46 307 232333 9826 42378869
Candida infection 273.41 11.46 452 232188 21158 42367537
Back pain 272.81 11.46 224 232416 141552 42247143
Depression 268.70 11.46 136 232504 111227 42277468
Disease recurrence 266.47 11.46 535 232105 29143 42359552
COVID-19 pneumonia 265.33 11.46 446 232194 21167 42367528
Graft loss 263.35 11.46 119 232521 796 42387899
Syncope 259.05 11.46 109 232531 99297 42289398
Renal tubular necrosis 256.94 11.46 402 232238 17952 42370743
Trichodysplasia spinulosa 255.95 11.46 92 232548 301 42388394
Hyperhidrosis 254.57 11.46 88 232552 90424 42298271
Stenotrophomonas infection 251.50 11.46 188 232452 3516 42385179
Viraemia 249.35 11.46 142 232498 1628 42387067
Human polyomavirus infection 249.09 11.46 128 232512 1175 42387520
Fungal skin infection 248.12 11.46 179 232461 3162 42385533
Death 246.46 11.46 1536 231104 469649 41919046
Squamous cell carcinoma of skin 244.55 11.46 324 232316 12402 42376293
Chronic obstructive pulmonary disease 243.94 11.46 29 232611 63085 42325610
Cystitis haemorrhagic 242.74 11.46 247 232393 7082 42381613
Disseminated cryptococcosis 240.89 11.46 143 232497 1782 42386913
Alveolar proteinosis 239.25 11.46 104 232536 626 42388069
Venoocclusive liver disease 237.16 11.46 287 232353 10015 42378680
Actinic keratosis 235.57 11.46 208 232432 4968 42383727
Epstein-Barr virus infection reactivation 233.13 11.46 157 232483 2470 42386225
Staphylococcal infection 231.83 11.46 584 232056 37059 42351636
Drug ineffective for unapproved indication 231.73 11.46 664 231976 45499 42343196
Renal graft infection 230.55 11.46 85 232555 305 42388390
Aplasia pure red cell 227.37 11.46 236 232404 6930 42381765
Pulmonary mucormycosis 224.74 11.46 124 232516 1331 42387364
Chest pain 219.49 11.46 263 232377 139267 42249428
Blood creatinine increased 218.39 11.46 1180 231460 108823 42279872
Histoplasmosis 213.88 11.46 129 232511 1658 42387037
Systemic mycosis 207.87 11.46 141 232499 2246 42386449
Peripheral swelling 207.81 11.46 117 232523 90153 42298542
Squamous cell carcinoma 206.79 11.46 302 232338 12680 42376015
Insomnia 204.61 11.46 206 232434 118047 42270648
Joint swelling 202.14 11.46 60 232580 67962 42320733
Intentional overdose 200.45 11.46 23 232617 51433 42337262
Dermatitis atopic 198.23 11.46 289 232351 12115 42376580
Proteinuria 195.27 11.46 405 232235 22578 42366117
Pneumonia cryptococcal 193.88 11.46 114 232526 1394 42387301
Dermatophytosis 193.84 11.46 70 232570 233 42388462
Decreased appetite 191.80 11.46 487 232153 192650 42196045
Progressive multifocal leukoencephalopathy 184.67 11.46 269 232371 11267 42377428
Feeling abnormal 184.23 11.46 75 232565 69711 42318984
Rhodococcus infection 180.41 11.46 69 232571 281 42388414
Monkeypox 179.49 11.46 72 232568 342 42388353
Muscle spasms 179.45 11.46 125 232515 85919 42302776
Platelet count decreased 179.42 11.46 300 232340 138281 42250414
Toxoplasmosis 176.98 11.46 110 232530 1497 42387198
Blood pressure increased 176.95 11.46 177 232463 101751 42286944
Suicide attempt 176.13 11.46 22 232618 46078 42342617
Disseminated mucormycosis 173.19 11.46 103 232537 1288 42387407
Enterobacter infection 172.39 11.46 138 232502 2866 42385829
Drug reaction with eosinophilia and systemic symptoms 171.13 11.46 16 232624 42059 42346636
Suicidal ideation 170.07 11.46 29 232611 48132 42340563
Acute graft versus host disease in liver 168.94 11.46 115 232525 1843 42386852
Organising pneumonia 167.16 11.46 206 232434 7326 42381369
Pulmonary embolism 166.15 11.46 247 232393 119365 42269330
Herpes simplex 165.50 11.46 199 232441 6896 42381799
Glomerulonephritis 164.83 11.46 126 232514 2440 42386255
Human herpesvirus 6 infection 164.43 11.46 125 232515 2400 42386295
Toxicity to various agents 163.80 11.46 1941 230699 227195 42161500
Musculoskeletal stiffness 162.67 11.46 56 232584 57709 42330986
Graft versus host disease in lung 162.12 11.46 80 232560 668 42388027
Bradycardia 159.50 11.46 139 232501 85345 42303350
Osmotic demyelination syndrome 158.38 11.46 87 232553 925 42387770
Asthma 158.05 11.46 71 232569 62243 42326452
Complications of transplanted lung 157.94 11.46 62 232578 275 42388420
Wheezing 157.94 11.46 51 232589 54730 42333965
Vaccination failure 157.68 11.46 99 232541 1373 42387322
Norovirus infection 157.27 11.46 79 232561 688 42388007
Lymphoproliferative disorder 156.73 11.46 136 232504 3171 42385524
Infusion related reaction 156.25 11.46 68 232572 60738 42327957
Nasopharyngitis 156.21 11.46 137 232503 83859 42304836
Hypersensitivity 155.10 11.46 102 232538 72268 42316427
Drug level above therapeutic 155.02 11.46 176 232464 5730 42382965
Cat scratch disease 154.31 11.46 62 232578 296 42388399
Atrial fibrillation 152.88 11.46 334 232306 139259 42249436
Gingival hypertrophy 152.81 11.46 118 232522 2321 42386374
Malacoplakia gastrointestinal 150.86 11.46 51 232589 131 42388564
Renal tubular acidosis 150.76 11.46 123 232517 2627 42386068
Pneumonia fungal 150.38 11.46 216 232424 8930 42379765
Mycobacterium abscessus infection 149.17 11.46 76 232564 684 42388011
Epistaxis 148.97 11.46 90 232550 66736 42321959
Hepatic artery thrombosis 148.38 11.46 56 232584 218 42388477
Mycobacterial infection 147.67 11.46 120 232520 2548 42386147
Inappropriate schedule of product administration 147.33 11.46 184 232456 95718 42292977
Trichophytosis 147.07 11.46 62 232578 342 42388353
Stress 146.80 11.46 31 232609 44181 42344514
Rheumatoid arthritis 146.71 11.46 27 232613 42413 42346282
Urticaria 146.03 11.46 114 232526 73922 42314773
Pneumonia pseudomonal 145.65 11.46 156 232484 4753 42383942
Angiosarcoma 144.74 11.46 60 232580 315 42388380
Smooth muscle cell neoplasm 144.55 11.46 56 232584 238 42388457
Pneumocystis jirovecii infection 144.48 11.46 122 232518 2738 42385957
Acinetobacter infection 144.30 11.46 95 232545 1436 42387259
Heart rate decreased 143.11 11.46 16 232624 36516 42352179
Drug level fluctuating 142.85 11.46 71 232569 603 42388092
Cardiac failure congestive 142.53 11.46 154 232486 85448 42303247
Weight increased 142.30 11.46 231 232409 107752 42280943
Hypoaesthesia 140.99 11.46 110 232530 71353 42317342
Obliterative bronchiolitis 140.98 11.46 92 232548 1369 42387326
Neuropathy peripheral 140.78 11.46 211 232429 101642 42287053
Graft complication 140.75 11.46 72 232568 654 42388041
Vomiting 140.07 11.46 966 231674 288757 42099938
Paraesthesia 140.03 11.46 117 232523 73342 42315353
Disseminated blastomycosis 137.98 11.46 59 232581 339 42388356
Neutrophil count decreased 137.77 11.46 88 232552 63327 42325368
Gait disturbance 137.42 11.46 201 232439 97799 42290896
Complications of transplanted liver 137.15 11.46 55 232585 261 42388434
New onset diabetes after transplantation 137.00 11.46 50 232590 173 42388522
Loss of consciousness 136.91 11.46 182 232458 92172 42296523
Mycoplasma infection 136.87 11.46 68 232572 577 42388118
Gastroenteritis norovirus 136.44 11.46 96 232544 1627 42387068
Rectal haemorrhage 136.41 11.46 50 232590 49556 42339139
Haemolytic uraemic syndrome 136.16 11.46 111 232529 2368 42386327
IgA nephropathy 136.11 11.46 109 232531 2265 42386430
Human herpesvirus 6 encephalitis 135.40 11.46 66 232574 535 42388160
Pyelonephritis 134.68 11.46 190 232450 7724 42380971
Necrotising oesophagitis 134.37 11.46 77 232563 894 42387801
Atypical mycobacterial infection 134.22 11.46 87 232553 1279 42387416
White blood cell count decreased 133.79 11.46 249 232391 110147 42278548
International normalised ratio increased 133.38 11.46 48 232592 48120 42340575
Encephalitis viral 132.44 11.46 90 232550 1438 42387257
Corynebacterium infection 130.23 11.46 73 232567 810 42387885
Rhabdomyolysis 129.17 11.46 141 232499 77878 42310817
Blood creatine phosphokinase increased 129.12 11.46 51 232589 48287 42340408
Lymphocele 129.07 11.46 89 232551 1458 42387237
Atypical haemolytic uraemic syndrome 127.78 11.46 62 232578 497 42388198
Mycetoma mycotic 127.04 11.46 54 232586 305 42388390
General physical health deterioration 126.87 11.46 413 232227 150833 42237862
Chest discomfort 124.13 11.46 99 232541 63517 42325178
Palpitations 124.01 11.46 61 232579 50736 42337959
Pruritus 123.96 11.46 569 232071 188202 42200493
Papilloma viral infection 123.95 11.46 66 232574 656 42388039
Renal transplant 123.64 11.46 104 232536 2321 42386374
Abdominal discomfort 123.49 11.46 137 232503 75118 42313577
Bacillary angiomatosis 122.90 11.46 46 232594 174 42388521
Microsporidia infection 122.20 11.46 77 232563 1075 42387620
Enterocolitis viral 121.52 11.46 57 232583 420 42388275
Hydronephrosis 121.28 11.46 226 232414 11639 42377056
Ureteric stenosis 121.09 11.46 79 232561 1175 42387520
Complications of transplanted heart 121.02 11.46 51 232589 281 42388414
Vascular pseudoaneurysm ruptured 120.84 11.46 57 232583 426 42388269
Hypoglycaemia 120.79 11.46 90 232550 59764 42328931
Anogenital warts 120.05 11.46 65 232575 670 42388025
Drug level decreased 119.93 11.46 204 232436 9773 42378922
Bacteraemia 119.67 11.46 354 232286 24686 42364009
Confusional state 119.28 11.46 490 232150 167107 42221588
Injection site pain 117.81 11.46 86 232554 57712 42330983
Intentional product misuse 117.47 11.46 99 232541 61801 42326894
Pseudoaneurysm infection 117.24 11.46 44 232596 168 42388527
Headache 116.66 11.46 796 231844 238573 42150122
Disseminated tuberculosis 115.75 11.46 107 232533 2717 42385978
Drug resistance 115.26 11.46 430 232210 33818 42354877
Balance disorder 115.12 11.46 58 232582 47587 42341108
Oxygen saturation decreased 114.92 11.46 110 232530 64577 42324118
Cerebrovascular accident 114.34 11.46 223 232417 96937 42291758
Neutrophil Pelger-Huet anomaly present 114.09 11.46 46 232594 222 42388473
Loss of personal independence in daily activities 113.98 11.46 65 232575 49751 42338944
Epidermodysplasia verruciformis 113.65 11.46 47 232593 245 42388450
Central nervous system infection 113.40 11.46 67 232573 827 42387868
Blood pressure decreased 112.29 11.46 92 232548 58240 42330455
Adenoviral haemorrhagic cystitis 111.55 11.46 56 232584 487 42388208
Skin papilloma 110.92 11.46 104 232536 2690 42386005
Chronic graft versus host disease oral 110.57 11.46 51 232589 360 42388335
Full blood count abnormal 109.97 11.46 16 232624 29860 42358835
Endophthalmitis 109.44 11.46 128 232512 4305 42384390
Pancreas transplant rejection 109.44 11.46 42 232598 173 42388522
Oedema peripheral 109.03 11.46 379 232261 135697 42252998
Agitation 108.95 11.46 114 232526 64200 42324495
Immune reconstitution inflammatory syndrome 107.19 11.46 196 232444 9947 42378748
Donor specific antibody present 106.41 11.46 39 232601 137 42388558
Angiosarcoma metastatic 106.04 11.46 34 232606 69 42388626
Encephalitis 105.81 11.46 184 232456 8974 42379721
Biliary anastomosis complication 105.72 11.46 34 232606 70 42388625
Transitional cell carcinoma 105.64 11.46 99 232541 2559 42386136
Pneumoperitoneum 105.10 11.46 94 232546 2284 42386411
Contusion 104.65 11.46 49 232591 41936 42346759
Pathogen resistance 104.65 11.46 208 232432 11242 42377453
Graft versus host disease in liver 104.22 11.46 80 232560 1559 42387136
Gastroenteritis cryptosporidial 104.00 11.46 43 232597 224 42388471
Nightmare 103.09 11.46 9 232631 25003 42363692
Hallucination 103.08 11.46 97 232543 57410 42331285
Cerebral aspergillosis 102.75 11.46 82 232558 1695 42387000
Complications of transplant surgery 102.44 11.46 52 232588 464 42388231
Penicillium infection 102.42 11.46 45 232595 279 42388416
Angioedema 102.19 11.46 52 232588 42425 42346270
Idiopathic pneumonia syndrome 101.93 11.46 51 232589 440 42388255
Osteomyelitis fungal 101.88 11.46 46 232594 307 42388388
Coronary artery disease 101.83 11.46 86 232554 53634 42335061
Transplantation associated food allergy 101.71 11.46 30 232610 39 42388656
Glomerulonephritis membranoproliferative 101.13 11.46 52 232588 478 42388217
Pneumonia klebsiella 100.91 11.46 120 232520 4109 42384586
Ureaplasma infection 100.43 11.46 55 232585 581 42388114
Mycobacterium haemophilum infection 99.92 11.46 49 232591 403 42388292
Wrong technique in product usage process 99.90 11.46 54 232586 42581 42346114
Acute myeloid leukaemia recurrent 99.63 11.46 109 232531 3403 42385292
Demodicidosis 99.38 11.46 40 232600 192 42388503
Renal artery stenosis 99.28 11.46 90 232550 2227 42386468
Pneumonia bacterial 99.25 11.46 246 232394 15446 42373249
Abdominal distension 98.72 11.46 149 232491 71586 42317109
Memory impairment 98.17 11.46 78 232562 50144 42338551
Mobility decreased 98.06 11.46 35 232605 35271 42353424
Hypokalaemia 97.71 11.46 150 232490 71571 42317124
Drug dependence 97.41 11.46 20 232620 29074 42359621
Cardiac disorder 96.91 11.46 75 232565 48857 42339838
Post procedural bile leak 96.89 11.46 43 232597 274 42388421
Chronic graft versus host disease in liver 96.54 11.46 55 232585 631 42388064
Sedation 95.92 11.46 24 232616 30451 42358244
Cytomegalovirus chorioretinitis 95.76 11.46 122 232518 4489 42384206
Hypogammaglobulinaemia 95.72 11.46 205 232435 11686 42377009
Lymphopenia 95.67 11.46 297 232343 21266 42367429
Tachycardia 95.56 11.46 261 232379 100826 42287869
Viral haemorrhagic cystitis 95.53 11.46 80 232560 1774 42386921
American trypanosomiasis 95.22 11.46 44 232596 312 42388383
Myalgia 94.67 11.46 243 232397 95837 42292858
Dry mouth 94.18 11.46 50 232590 39829 42348866
Prostate cancer 94.18 11.46 64 232576 44579 42344116
Heart rate increased 94.08 11.46 91 232549 53164 42335531
Chronic graft versus host disease in eye 94.01 11.46 41 232599 249 42388446
Vascular hyalinosis 93.20 11.46 33 232607 102 42388593
Tubulointerstitial nephritis 93.07 11.46 380 232260 31168 42357527
Cardiac failure 92.21 11.46 288 232352 106568 42282127
Drug ineffective 91.86 11.46 4258 228382 625939 41762756
Glomerulosclerosis 91.66 11.46 58 232582 816 42387879
Infection in an immunocompromised host 91.00 11.46 62 232578 995 42387700
Aggression 90.93 11.46 65 232575 44098 42344597
Arthritis 90.50 11.46 59 232581 42006 42346689
Acanthamoeba infection 90.33 11.46 48 232592 475 42388220
Fusarium infection 90.11 11.46 73 232567 1543 42387152
Pancytopenia 89.10 11.46 1009 231631 116734 42271961
Cytomegalovirus gastritis 88.96 11.46 40 232600 264 42388431
Human ehrlichiosis 88.80 11.46 47 232593 461 42388234
Hepatocellular carcinoma 88.70 11.46 160 232480 8034 42380661
Enterovirus infection 88.61 11.46 66 232574 1227 42387468
Visceral leishmaniasis 88.38 11.46 63 232577 1091 42387604
Arthropathy 88.09 11.46 26 232614 29571 42359124
Cutaneous malacoplakia 87.40 11.46 32 232608 112 42388583
Disseminated varicella zoster virus infection 87.38 11.46 54 232586 727 42387968
Central nervous system lymphoma 86.75 11.46 67 232573 1318 42387377
Nodular regenerative hyperplasia 86.75 11.46 60 232580 988 42387707
Chronic hepatitis 86.56 11.46 53 232587 701 42387994
Gastroenteritis sapovirus 86.22 11.46 34 232606 153 42388542
Cytomegalovirus gastrointestinal infection 86.08 11.46 41 232599 314 42388381
Encephalopathy 85.73 11.46 449 232191 40884 42347811
Dehydration 85.65 11.46 440 232200 141327 42247368
Gastrointestinal mucormycosis 85.28 11.46 42 232598 349 42388346
Ileal ulcer 85.16 11.46 57 232583 887 42387808
Chronic kidney disease 85.14 11.46 494 232146 46747 42341948
Dysgeusia 85.05 11.46 40 232600 34149 42354546
Choroiditis 85.00 11.46 66 232574 1309 42387386
Flatulence 84.81 11.46 17 232623 25135 42363560
Febrile neutropenia 84.33 11.46 630 232010 185073 42203622
Cystitis viral 84.23 11.46 63 232577 1179 42387516
Fungal endocarditis 84.15 11.46 44 232596 420 42388275
Flushing 83.73 11.46 49 232591 36979 42351716
Tinnitus 83.30 11.46 27 232613 28911 42359784
Therapeutic product effect decreased 82.75 11.46 56 232584 39094 42349601
Mycobacterium avium complex infection 82.51 11.46 92 232548 2935 42385760
Cytokine release syndrome 82.30 11.46 73 232567 44454 42344241
Nephropathy 81.34 11.46 140 232500 6771 42381924
Hypertrophic cardiomyopathy 81.31 11.46 66 232574 1399 42387296
Neck pain 81.25 11.46 31 232609 29983 42358712
Bacterial sepsis 81.18 11.46 135 232505 6347 42382348
Non-cirrhotic portal hypertension 80.95 11.46 41 232599 364 42388331
Oliguria 80.13 11.46 165 232475 9148 42379547
Hot flush 79.92 11.46 13 232627 22338 42366357
Unevaluable event 79.50 11.46 44 232596 34244 42354451
Pyelonephritis acute 78.71 11.46 82 232558 2418 42386277
Cough 78.61 11.46 609 232031 177494 42211201
Muscular weakness 78.60 11.46 216 232424 83282 42305413
Herpes simplex hepatitis 78.53 11.46 31 232609 140 42388555
Mycobacterium chelonae infection 78.21 11.46 59 232581 1119 42387576
Muscle abscess 78.03 11.46 54 232586 890 42387805
Nephrotic syndrome 78.03 11.46 157 232483 8561 42380134
Encapsulating peritoneal sclerosis 77.98 11.46 46 232594 566 42388129
Urinoma 77.59 11.46 35 232605 233 42388462
Herpes zoster meningoencephalitis 76.95 11.46 43 232597 474 42388221
Incorrect route of product administration 76.77 11.46 19 232621 24286 42364409
Weight decreased 76.70 11.46 745 231895 207203 42181492
Cardio-respiratory arrest 76.68 11.46 126 232514 58510 42330185
Meningoencephalitis viral 76.16 11.46 31 232609 154 42388541
Therapeutic product effect incomplete 75.73 11.46 172 232468 70767 42317928
Cerebral toxoplasmosis 75.54 11.46 74 232566 2024 42386671
Liver transplant 75.44 11.46 83 232557 2608 42386087
Cryptococcal cutaneous infection 75.38 11.46 30 232610 139 42388556
Cerebral fungal infection 75.06 11.46 38 232602 337 42388358
Thrombosis 74.87 11.46 164 232476 68347 42320348
Chills 74.63 11.46 263 232377 93803 42294892
Adverse drug reaction 74.60 11.46 57 232583 37377 42351318
Choriomeningitis lymphocytic 74.35 11.46 29 232611 126 42388569
Abdominal pain upper 73.86 11.46 219 232421 82390 42306305
Dermoid cyst 73.55 11.46 30 232610 150 42388545
Herpes simplex pneumonia 72.77 11.46 34 232606 248 42388447
Inflammatory bowel disease 72.70 11.46 93 232547 3436 42385259
Sepsis 72.65 11.46 1508 231132 197826 42190869
Humoral immune defect 72.62 11.46 37 232603 333 42388362
Emphysematous cystitis 72.55 11.46 34 232606 250 42388445
Cytomegalovirus enteritis 72.17 11.46 45 232595 616 42388079
Scleroderma 72.16 11.46 67 232573 1711 42386984
Cytomegalovirus oesophagitis 72.01 11.46 43 232597 542 42388153
Engraftment syndrome 71.67 11.46 60 232580 1330 42387365
Histology abnormal 71.62 11.46 36 232604 314 42388381
Overdose 71.59 11.46 313 232327 104951 42283744
Transplantation complication 71.53 11.46 33 232607 233 42388462
Acute myocardial infarction 71.48 11.46 130 232510 58035 42330660
Mycobacterium fortuitum infection 71.25 11.46 38 232602 379 42388316
Opportunistic infection 70.97 11.46 70 232570 1931 42386764
Mediastinitis 70.85 11.46 53 232587 992 42387703
Epstein-Barr virus test positive 70.76 11.46 45 232595 639 42388056
Gastrooesophageal reflux disease 70.56 11.46 85 232555 44938 42343757
Pneumomediastinum 70.40 11.46 86 232554 3030 42385665
Transient ischaemic attack 70.32 11.46 49 232591 33690 42355005
Bacterial pyelonephritis 69.95 11.46 35 232605 302 42388393
Bile duct stenosis 69.68 11.46 59 232581 1329 42387366
Cytomegalovirus nephritis 69.46 11.46 27 232613 116 42388579
Pericarditis fungal 69.02 11.46 31 232609 204 42388491
Food allergy 68.40 11.46 72 232568 2149 42386546
Low birth weight baby 68.24 11.46 161 232479 9794 42378901
Oesophageal achalasia 68.23 11.46 38 232602 416 42388279
Cutaneous mucormycosis 68.13 11.46 43 232597 602 42388093
Inferior vena cava stenosis 68.07 11.46 24 232616 73 42388622
Respiratory arrest 68.06 11.46 35 232605 28389 42360306
Cytomegalovirus enterocolitis 67.82 11.46 58 232582 1325 42387370
Hepatic fibrosis 67.18 11.46 106 232534 4766 42383929
Haematochezia 67.11 11.46 136 232504 58300 42330395
Kaposi sarcoma inflammatory cytokine syndrome 66.85 11.46 27 232613 131 42388564
Prophylaxis against transplant rejection 66.71 11.46 21 232619 39 42388656
Hypothyroidism 66.34 11.46 47 232593 32037 42356658
Adenoviral hepatitis 65.99 11.46 40 232600 519 42388176
Bronchitis 65.94 11.46 97 232543 47104 42341591
Labelled drug-drug interaction medication error 65.80 11.46 211 232429 15371 42373324
Wound dehiscence 65.80 11.46 92 232548 3708 42384987
Autoimmune haemolytic anaemia 65.59 11.46 114 232526 5557 42383138
Disseminated strongyloidiasis 65.55 11.46 39 232601 488 42388207
Blood glucose increased 65.44 11.46 196 232444 73503 42315192
Renal vein thrombosis 65.38 11.46 38 232602 454 42388241
Hepatic cancer recurrent 65.34 11.46 33 232607 291 42388404
Dysphonia 65.25 11.46 37 232603 28413 42360282
Glomerulonephritis membranous 65.10 11.46 58 232582 1402 42387293
Steroid diabetes 64.90 11.46 79 232561 2773 42385922
Prostatic specific antigen increased 64.83 11.46 8 232632 16917 42371778
Cutaneous nocardiosis 64.80 11.46 29 232611 189 42388506
Kaposi's sarcoma 64.60 11.46 45 232595 750 42387945
Philadelphia positive chronic myeloid leukaemia 64.23 11.46 26 232614 127 42388568
Pneumonia necrotising 64.04 11.46 51 232589 1051 42387644
Malignant fibrous histiocytoma 63.94 11.46 31 232609 248 42388447
Infectious pleural effusion 63.94 11.46 83 232557 3112 42385583
Meningitis viral 63.91 11.46 51 232589 1054 42387641
Neuroendocrine carcinoma of the skin 63.69 11.46 48 232592 909 42387786
Liver transplant failure 63.68 11.46 24 232616 93 42388602
Infective aneurysm 63.66 11.46 50 232590 1009 42387686
Serotonin syndrome 63.12 11.46 31 232609 25814 42362881
Respiratory depression 63.10 11.46 13 232627 18855 42369840
Superinfection bacterial 63.05 11.46 56 232584 1348 42387347
Liver abscess 62.90 11.46 104 232536 4866 42383829
Emphysematous pyelonephritis 62.18 11.46 27 232613 162 42388533
Chromoblastomycosis 62.13 11.46 24 232616 101 42388594
Burkholderia cepacia complex infection 61.97 11.46 32 232608 297 42388398
Hyperkalaemia 61.96 11.46 692 231948 79766 42308929
Metastatic squamous cell carcinoma 61.92 11.46 41 232599 626 42388069
C3 glomerulopathy 61.88 11.46 26 232614 142 42388553
Atypical mycobacterial pneumonia 61.68 11.46 29 232611 215 42388480
Orthostatic hypotension 61.62 11.46 46 232594 30524 42358171
Adverse event 61.41 11.46 26 232614 23614 42365081
Polyomavirus test positive 61.37 11.46 27 232613 168 42388527
Neuralgia 60.79 11.46 32 232608 25615 42363080
Bronchiolitis obliterans syndrome 60.75 11.46 31 232609 280 42388415
Abscess fungal 60.62 11.46 32 232608 312 42388383
Coronavirus infection 60.55 11.46 105 232535 5109 42383586
Drug withdrawal syndrome 60.46 11.46 21 232619 21528 42367167
Sleep disorder 60.44 11.46 106 232534 47989 42340706
Meningoencephalitis herpetic 60.40 11.46 48 232592 986 42387709
Central nervous system fungal infection 60.23 11.46 35 232605 418 42388277
Subcapsular renal haematoma 60.21 11.46 38 232602 532 42388163
Aspergilloma 60.08 11.46 35 232605 420 42388275
Passenger lymphocyte syndrome 59.87 11.46 22 232618 78 42388617
Oropharyngeal pain 59.73 11.46 87 232553 42423 42346272
Aspartate aminotransferase increased 59.70 11.46 218 232422 76945 42311750
Trichosporon infection 59.51 11.46 46 232594 906 42387789
Lung consolidation 59.46 11.46 120 232520 6557 42382138
Urinary tract infection bacterial 59.45 11.46 69 232571 2301 42386394
Glomerulonephritis proliferative 59.29 11.46 29 232611 237 42388458
Enterococcal bacteraemia 59.27 11.46 73 232567 2594 42386101
Erectile dysfunction 59.17 11.46 31 232609 24882 42363813
Swollen tongue 59.04 11.46 21 232619 21210 42367485
Heartland virus infection 59.02 11.46 17 232623 19 42388676
Erythema infectiosum 58.99 11.46 25 232615 140 42388555
Herpes zoster oticus 58.98 11.46 29 232611 240 42388455
Enterococcal sepsis 58.96 11.46 64 232576 1980 42386715
Solar lentigo 58.93 11.46 39 232601 595 42388100
Intentional self-injury 58.68 11.46 7 232633 15195 42373500
Necrotising retinitis 58.43 11.46 47 232593 983 42387712
Dysplastic naevus 58.39 11.46 40 232600 648 42388047
Diabetes mellitus 58.34 11.46 542 232098 59545 42329150
Microangiopathic haemolytic anaemia 58.08 11.46 49 232591 1098 42387597
Toxic optic neuropathy 58.03 11.46 47 232593 993 42387702
Palmar-plantar erythrodysaesthesia syndrome 57.85 11.46 20 232620 20562 42368133
Appendicolith 57.82 11.46 4 232636 13452 42375243
Anaphylactic shock 57.75 11.46 28 232612 23489 42365206
Intestine transplant rejection 57.68 11.46 18 232622 32 42388663
Disturbance in attention 57.59 11.46 47 232593 29819 42358876
Escherichia urinary tract infection 57.52 11.46 93 232547 4270 42384425
Periostitis 57.22 11.46 31 232609 320 42388375
Migraine 56.93 11.46 34 232606 25380 42363315
Dyskinesia 56.84 11.46 34 232606 25356 42363339
End stage renal disease 56.62 11.46 209 232431 16349 42372346
Toxic skin eruption 56.42 11.46 5 232635 13725 42374970
Myasthenia gravis 56.34 11.46 10 232630 16127 42372568
Blood pressure fluctuation 56.18 11.46 39 232601 26869 42361826
Joint injury 56.06 11.46 7 232633 14669 42374026
Anuria 56.01 11.46 164 232476 11368 42377327
SARS-CoV-2 viraemia 55.99 11.46 21 232619 80 42388615
Heart rate irregular 55.92 11.46 10 232630 16040 42372655
Fungaemia 55.91 11.46 77 232563 3059 42385636
Central nervous system viral infection 55.27 11.46 24 232616 144 42388551
Eczema herpeticum 55.27 11.46 29 232611 279 42388416
Dengue fever 55.19 11.46 33 232607 417 42388278
Stevens-Johnson syndrome 55.08 11.46 26 232614 22152 42366543
Miosis 54.97 11.46 5 232635 13441 42375254
Nasal congestion 54.96 11.46 48 232592 29453 42359242
Morganella infection 54.94 11.46 37 232603 582 42388113
Dyspnoea exertional 54.82 11.46 120 232520 50028 42338667
Photodermatosis 54.80 11.46 40 232600 720 42387975
Herpes virus infection 54.65 11.46 83 232557 3609 42385086
Disease progression 54.47 11.46 511 232129 143145 42245550
Chronic graft versus host disease in intestine 54.32 11.46 33 232607 430 42388265
Obstructive airways disorder 54.25 11.46 34 232606 24725 42363970
Rhinorrhoea 54.23 11.46 56 232584 31738 42356957
Large intestinal ulcer 54.06 11.46 67 232573 2396 42386299
Haemoglobin decreased 53.82 11.46 463 232177 132008 42256687
Abdominal wall abscess 53.81 11.46 38 232602 648 42388047
Skin squamous cell carcinoma metastatic 53.78 11.46 20 232620 74 42388621
Biliary tract disorder 53.76 11.46 47 232593 1107 42387588
Contraindicated product administered 53.61 11.46 36 232604 25236 42363459
Reversible cerebral vasoconstriction syndrome 53.48 11.46 39 232601 701 42387994
Arrhythmia 53.30 11.46 86 232554 40231 42348464
Erythema 53.27 11.46 361 232279 108432 42280263
Granuloma 53.09 11.46 86 232554 3955 42384740
Abnormal behaviour 53.06 11.46 40 232600 26411 42362284
Locked-in syndrome 52.93 11.46 31 232609 376 42388319
Paranoia 52.82 11.46 7 232633 14019 42374676
Pulmonary tuberculosis 52.77 11.46 102 232538 5399 42383296
Troponin increased 52.75 11.46 19 232621 19043 42369652
Clostridium difficile colitis 52.73 11.46 243 232397 21009 42367686
Osteonecrosis of jaw 52.70 11.46 19 232621 19030 42369665
Medication error 52.58 11.46 62 232578 33092 42355603
Guillain-Barre syndrome 52.57 11.46 120 232520 7143 42381552
Lung transplant 52.53 11.46 65 232575 2321 42386374
Lethargy 52.25 11.46 111 232529 46779 42341916
Postoperative wound infection 52.16 11.46 103 232537 5539 42383156
Upper gastrointestinal haemorrhage 52.10 11.46 53 232587 30246 42358449
Hyponatraemia 52.04 11.46 332 232308 101130 42287565
Staphylococcal bacteraemia 51.97 11.46 156 232484 10965 42377730
Product prescribing error 51.72 11.46 40 232600 26072 42362623
Blood pressure systolic increased 51.50 11.46 46 232594 27922 42360773
Osteoarthritis 51.45 11.46 35 232605 24370 42364325
Trench fever 51.33 11.46 17 232623 40 42388655
Venoocclusive disease 51.00 11.46 83 232557 3832 42384863
Haemodialysis 50.88 11.46 147 232493 10113 42378582
Primary effusion lymphoma 50.73 11.46 16 232624 30 42388665
Neoplasm progression 50.70 11.46 50 232590 28950 42359745
Drug level changed 50.52 11.46 30 232610 374 42388321
Anaphylactic reaction 50.34 11.46 98 232542 42645 42346050
Device issue 50.26 11.46 7 232633 13502 42375193
Hepatic artery stenosis 50.26 11.46 23 232617 159 42388536
Musculoskeletal pain 50.09 11.46 65 232575 33275 42355420
Bone marrow transplant rejection 50.03 11.46 25 232615 215 42388480
Cold sweat 49.77 11.46 3 232637 11327 42377368
Amnesia 49.75 11.46 49 232591 28388 42360307
Injection site erythema 49.66 11.46 24 232616 20171 42368524
B-cell lymphoma 49.48 11.46 93 232547 4820 42383875
Histoplasmosis cutaneous 49.41 11.46 16 232624 34 42388661
Oesophageal ulcer 49.38 11.46 80 232560 3679 42385016
Gait inability 49.14 11.46 32 232608 22801 42365894
Neuroleptic malignant syndrome 49.13 11.46 28 232612 21444 42367251
Intestinal tuberculosis 48.83 11.46 22 232618 146 42388549
Swelling 48.69 11.46 146 232494 54739 42333956
Muir-Torre syndrome 48.44 11.46 14 232626 16 42388679
Optic neuropathy 48.32 11.46 64 232576 2448 42386247
Injection site reaction 48.29 11.46 13 232627 15708 42372987
Nephrolithiasis 48.28 11.46 79 232561 36751 42351944
Skin lesion 48.20 11.46 283 232357 26891 42361804
Impaired work ability 48.10 11.46 5 232635 12086 42376609
Road traffic accident 48.01 11.46 22 232618 19071 42369624
Lip swelling 47.84 11.46 22 232618 19031 42369664
Withdrawal syndrome 47.74 11.46 11 232629 14764 42373931
Bone pain 47.70 11.46 36 232604 23756 42364939
Sinusitis fungal 47.64 11.46 37 232603 734 42387961
Synovitis 47.58 11.46 13 232627 15554 42373141
Drug eruption 47.45 11.46 34 232606 23041 42365654
Graft infection 47.29 11.46 30 232610 424 42388271
Hepatic cytolysis 47.25 11.46 46 232594 26798 42361897
Burning sensation 47.23 11.46 28 232612 20985 42367710
Rhinovirus infection 47.18 11.46 108 232532 6440 42382255
Epstein-Barr virus associated lymphoma 46.84 11.46 42 232598 1024 42387671
Sopor 46.49 11.46 8 232632 13194 42375501
Cutaneous blastomycosis 46.29 11.46 15 232625 32 42388663
Klebsiella sepsis 46.18 11.46 65 232575 2636 42386059
Perinephric collection 46.02 11.46 22 232618 170 42388525
Disseminated paracoccidioidomycosis 45.87 11.46 13 232627 13 42388682
Laboratory test abnormal 45.77 11.46 35 232605 22943 42365752
Abdominal pain 45.56 11.46 748 231892 189723 42198972
Skin necrosis 45.34 11.46 104 232536 6210 42382485
Injection site bruising 45.25 11.46 5 232635 11520 42377175
Dyspepsia 45.16 11.46 99 232541 41253 42347442
Hypoacusis 44.82 11.46 23 232617 18679 42370016
Toxic epidermal necrolysis 44.63 11.46 48 232592 26702 42361993
Portal vein thrombosis 44.44 11.46 85 232555 4464 42384231
Injury 44.44 11.46 34 232606 22282 42366413
Urinary fistula 44.17 11.46 19 232621 111 42388584
Body temperature decreased 44.12 11.46 12 232628 14401 42374294
Meningitis fungal 44.05 11.46 22 232618 189 42388506
Full blood count decreased 44.00 11.46 29 232611 20531 42368164
Gastrointestinal fungal infection 43.87 11.46 24 232616 253 42388442
Underdose 43.82 11.46 18 232622 16648 42372047
Postoperative thoracic procedure complication 43.71 11.46 15 232625 41 42388654
Biopsy kidney abnormal 43.62 11.46 19 232621 115 42388580
Klebsiella bacteraemia 43.59 11.46 59 232581 2305 42386390
Blood potassium decreased 43.28 11.46 29 232611 20355 42368340
Dysphagia 43.14 11.46 227 232413 72492 42316203
Candida sepsis 43.01 11.46 46 232594 1399 42387296
Tularaemia 42.79 11.46 21 232619 173 42388522
Feeling hot 42.79 11.46 39 232601 23443 42365252
Urosepsis 42.78 11.46 179 232461 14841 42373854
Parvovirus infection 42.69 11.46 29 232611 463 42388232
Graft thrombosis 42.68 11.46 24 232616 268 42388427
Yersinia infection 42.65 11.46 16 232624 61 42388634
Disseminated intravascular coagulation 42.55 11.46 256 232384 24538 42364157
Mouth ulceration 42.37 11.46 178 232462 14785 42373910
Cytomegalovirus gastroenteritis 42.35 11.46 25 232615 308 42388387
Bacterial infection 42.34 11.46 279 232361 27600 42361095
Cognitive disorder 42.31 11.46 76 232564 34096 42354599
Oesophageal stenosis 42.27 11.46 54 232586 1992 42386703
Lung abscess 42.26 11.46 69 232571 3194 42385501
Thyroid gland abscess 42.25 11.46 16 232624 63 42388632
Neutralising antibodies negative 42.16 11.46 10 232630 0 42388695
Graft versus host disease in eye 42.08 11.46 25 232615 312 42388383
Orf 42.05 11.46 13 232627 22 42388673
Ventricular remodelling 42.00 11.46 17 232623 83 42388612
Acarodermatitis 41.95 11.46 34 232606 719 42387976
Plasma cell myeloma 41.89 11.46 127 232513 47451 42341244
Hepatic failure 41.79 11.46 353 232287 37747 42350948
Basal cell carcinoma 41.78 11.46 239 232401 22494 42366201
Pneumonia aspiration 41.75 11.46 137 232503 49941 42338754
Pancreatitis necrotising 41.74 11.46 73 232567 3576 42385119
Isosporiasis 41.59 11.46 18 232622 107 42388588
Renal-limited thrombotic microangiopathy 41.36 11.46 23 232617 251 42388444
Ecthyma 41.15 11.46 32 232608 636 42388059
Breath sounds abnormal 41.13 11.46 8 232632 12085 42376610
Blood phosphorus increased 41.12 11.46 9 232631 12516 42376179
Irritability 41.07 11.46 56 232584 28072 42360623
Pain in jaw 40.91 11.46 14 232626 14488 42374207
Frequent bowel movements 40.89 11.46 34 232606 21373 42367322
Urinary tract infection viral 40.86 11.46 14 232626 38 42388657
Epstein Barr virus positive mucocutaneous ulcer 40.77 11.46 30 232610 547 42388148
Hepatic necrosis 40.57 11.46 75 232565 3838 42384857
Purtscher retinopathy 40.44 11.46 15 232625 55 42388640
Intracranial pressure increased 40.43 11.46 83 232557 4591 42384104
Renal failure 40.14 11.46 1048 231592 142678 42246017
Sinusitis aspergillus 40.14 11.46 17 232623 95 42388600
Restlessness 39.98 11.46 61 232579 29188 42359507
Legionella infection 39.95 11.46 30 232610 565 42388130
Cyanosis 39.90 11.46 16 232624 15015 42373680
Blood immunoglobulin A decreased 39.87 11.46 32 232608 667 42388028
Presyncope 39.83 11.46 38 232602 22349 42366346
Diaphragmatic hernia 39.69 11.46 24 232616 310 42388385
Chronic inflammatory demyelinating polyradiculoneuropathy 39.65 11.46 41 232599 1198 42387497
Pulmonary mass 39.63 11.46 185 232455 16080 42372615
Protothecosis 39.62 11.46 15 232625 59 42388636
Extrapyramidal disorder 39.60 11.46 20 232620 16392 42372303
Skin squamous cell carcinoma recurrent 39.57 11.46 17 232623 99 42388596
Fungal abscess central nervous system 39.40 11.46 19 232621 150 42388545
Haemosiderosis 39.23 11.46 24 232616 317 42388378
Faeces discoloured 39.20 11.46 22 232618 16992 42371703
Angina pectoris 39.11 11.46 75 232565 32821 42355874
Seizure 39.06 11.46 445 232195 120116 42268579
Arteritis infective 39.04 11.46 15 232625 62 42388633
Pneumopericardium 39.03 11.46 18 232622 127 42388568
Head injury 38.93 11.46 33 232607 20549 42368146
Skin graft rejection 38.84 11.46 13 232627 32 42388663
Pasteurella infection 38.74 11.46 17 232623 105 42388590
Ejection fraction decreased 38.70 11.46 38 232602 22049 42366646
Tick-borne viral encephalitis 38.57 11.46 12 232628 21 42388674
Influenza like illness 38.37 11.46 72 232568 31768 42356927
Cytomegalovirus hepatitis 38.31 11.46 28 232612 505 42388190
Eosinophilic colitis 38.30 11.46 23 232617 293 42388402
Blood cholesterol increased 38.28 11.46 54 232586 26687 42362008
Reticulocytopenia 38.26 11.46 19 232621 161 42388534
Mycobacterium marinum infection 38.22 11.46 28 232612 507 42388188
Hypersomnia 38.09 11.46 16 232624 14602 42374093
Sleep apnoea syndrome 38.06 11.46 37 232603 21571 42367124
Oesophageal perforation 38.02 11.46 40 232600 1193 42387502
Gastroenteritis adenovirus 37.89 11.46 20 232620 195 42388500
Peritonitis pneumococcal 37.87 11.46 12 232628 23 42388672
Gastric haemorrhage 37.85 11.46 6 232634 10509 42378186
Appendicitis 37.84 11.46 34 232606 20579 42368116
Infectious thyroiditis 37.83 11.46 17 232623 112 42388583
Akathisia 37.54 11.46 6 232634 10445 42378250
Injection site haemorrhage 37.40 11.46 9 232631 11727 42376968
Psoriatic arthropathy 37.17 11.46 49 232591 24918 42363777
White blood cell count increased 37.14 11.46 124 232516 44963 42343732
Septic embolus 37.09 11.46 42 232598 1363 42387332
Rash pruritic 37.06 11.46 80 232560 33523 42355172
Cutaneous T-cell lymphoma 37.05 11.46 50 232590 1948 42386747
Accidental exposure to product 37.00 11.46 34 232606 20359 42368336
Gastroenteritis Escherichia coli 36.99 11.46 35 232605 916 42387779
Pallor 36.89 11.46 63 232577 28823 42359872
Chronic myeloid leukaemia 36.85 11.46 56 232584 2436 42386259
Drug effective for unapproved indication 36.80 11.46 99 232541 6534 42382161
Emotional distress 36.80 11.46 21 232619 16072 42372623
Cardiogenic shock 36.75 11.46 88 232552 35552 42353143
Electrocardiogram QT prolonged 36.72 11.46 136 232504 47809 42340886
Hepatic vein occlusion 36.71 11.46 21 232619 243 42388452
Necrosis 36.63 11.46 99 232541 6552 42382143
Hepatic infection fungal 36.56 11.46 21 232619 245 42388450
Odynophagia 36.51 11.46 100 232540 6670 42382025
Cardiac infection 36.41 11.46 21 232619 247 42388448
C-reactive protein abnormal 36.41 11.46 4 232636 9257 42379438
Hepatitis C RNA increased 36.39 11.46 22 232618 284 42388411
Arterial haemorrhage 36.36 11.46 39 232601 1190 42387505
Cholangitis 36.34 11.46 135 232505 10592 42378103
Nocardia sepsis 36.30 11.46 12 232628 28 42388667
Meningoencephalitis amoebic 36.22 11.46 20 232620 215 42388480
Metastases to salivary gland 36.14 11.46 15 232625 79 42388616
Engraft failure 36.07 11.46 28 232612 555 42388140
Prostatic abscess 36.07 11.46 31 232609 713 42387982
Metastases to nervous system 36.06 11.46 13 232627 43 42388652
Sebaceous carcinoma 35.99 11.46 15 232625 80 42388615
Coccidioidomycosis 35.99 11.46 33 232607 829 42387866
Dysarthria 35.95 11.46 105 232535 39702 42348993
Empyema 35.89 11.46 74 232566 4106 42384589
Deep vein thrombosis 35.87 11.46 259 232381 76698 42311997
Optic atrophy 35.84 11.46 39 232601 1210 42387485
Eccrine carcinoma 35.81 11.46 11 232629 18 42388677
Urinary tract infection enterococcal 35.69 11.46 36 232604 1021 42387674
Salivary hypersecretion 35.65 11.46 8 232632 10935 42377760
Blood immunoglobulin G decreased 35.65 11.46 53 232587 2261 42386434
Ureteral necrosis 35.61 11.46 13 232627 45 42388650
Post procedural urine leak 35.49 11.46 17 232623 132 42388563
Oxalosis 35.45 11.46 12 232628 31 42388664
Alanine aminotransferase increased 35.43 11.46 310 232330 88096 42300599
Renal tubular disorder 35.41 11.46 81 232559 4828 42383867
Aortic pseudoaneurysm 35.40 11.46 13 232627 46 42388649
Arteriosclerosis coronary artery 35.26 11.46 30 232610 18647 42370048
Transplant 35.00 11.46 34 232606 920 42387775
Escherichia bacteraemia 34.99 11.46 83 232557 5066 42383629
Endocarditis 34.97 11.46 111 232529 8041 42380654
Poor quality sleep 34.87 11.46 5 232635 9435 42379260
Limb discomfort 34.87 11.46 13 232627 12754 42375941
Pollakiuria 34.72 11.46 43 232597 22462 42366233
Depressed mood 34.71 11.46 46 232594 23338 42365357
Vascular pseudoaneurysm 34.66 11.46 57 232583 2655 42386040
Anastomotic stenosis 34.60 11.46 24 232616 397 42388298
Anger 34.32 11.46 14 232626 13004 42375691
Iron deficiency 34.25 11.46 9 232631 11052 42377643
Skin laceration 34.12 11.46 17 232623 14041 42374654
Speech disorder 34.09 11.46 67 232573 29054 42359641
Febrile bone marrow aplasia 34.07 11.46 7 232633 10174 42378521
Metastases to lung 34.00 11.46 138 232502 11286 42377409
Vision blurred 33.91 11.46 164 232476 53535 42335160
Subdural haematoma 33.85 11.46 46 232594 23092 42365603
Renal arteriosclerosis 33.83 11.46 21 232619 285 42388410
Pneumocephalus 33.80 11.46 18 232622 179 42388516
Superinfection 33.71 11.46 59 232581 2892 42385803
Orbital infection 33.60 11.46 13 232627 55 42388640
Premature baby 33.53 11.46 229 232411 22924 42365771
Lower respiratory tract infection 33.48 11.46 114 232526 41092 42347603
Swelling face 33.47 11.46 62 232578 27492 42361203
Systemic candida 33.22 11.46 83 232557 5236 42383459
Haematemesis 33.22 11.46 72 232568 30127 42358568
Disseminated aspergillosis 33.16 11.46 44 232596 1686 42387009
Hip fracture 33.14 11.46 16 232624 13456 42375239
Impaired quality of life 33.14 11.46 18 232622 14159 42374536
Respiratory syncytial virus infection 33.11 11.46 100 232540 7052 42381643
Scrotal ulcer 33.06 11.46 25 232615 476 42388219
Diffuse large B-cell lymphoma stage IV 33.01 11.46 26 232614 527 42388168
Vertigo 32.94 11.46 88 232552 34259 42354436
Hypoaldosteronism 32.85 11.46 21 232619 301 42388394
Red blood cell sedimentation rate increased 32.85 11.46 7 232633 9917 42378778
Varicella 32.82 11.46 48 232592 2017 42386678
H1N1 influenza 32.80 11.46 36 232604 1128 42387567
Dysstasia 32.76 11.46 18 232622 14068 42374627
Incorrect dose administered 32.75 11.46 163 232477 52811 42335884
Hyperammonaemia 32.74 11.46 106 232534 7760 42380935
Renal lymphocele 32.71 11.46 13 232627 60 42388635
Micturition urgency 32.69 11.46 12 232628 11886 42376809
Shock haemorrhagic 32.68 11.46 175 232465 16067 42372628
Hyperphosphataemia 32.67 11.46 15 232625 12989 42375706
Cytokine storm 32.64 11.46 32 232608 876 42387819
Disseminated cytomegaloviral infection 32.63 11.46 20 232620 265 42388430
Disseminated mycobacterium avium complex infection 32.62 11.46 19 232621 228 42388467
Feeling cold 32.54 11.46 15 232625 12958 42375737
BK polyomavirus test positive 32.53 11.46 13 232627 61 42388634
Depressed level of consciousness 32.37 11.46 143 232497 47827 42340868
Injection site swelling 32.36 11.46 27 232613 16946 42371749
Bartonellosis 32.34 11.46 11 232629 29 42388666
Infection protozoal 32.32 11.46 10 232630 17 42388678
Endocarditis bacterial 32.31 11.46 37 232603 1216 42387479
Ventricular tachycardia 32.28 11.46 73 232567 30087 42358608
Pharyngeal polyp 32.27 11.46 9 232631 8 42388687
Increased appetite 32.24 11.46 5 232635 8901 42379794
Product quality issue 32.22 11.46 30 232610 17852 42370843
Eye abscess 32.18 11.46 17 232623 166 42388529
Anaplastic large cell lymphoma T- and null-cell types 32.18 11.46 16 232624 136 42388559
Urinary retention 32.16 11.46 120 232520 42094 42346601
Psoriasis 32.13 11.46 146 232494 48458 42340237
Disseminated varicella zoster vaccine virus infection 32.03 11.46 13 232627 64 42388631
Herpes zoster cutaneous disseminated 32.01 11.46 18 232622 201 42388494
Tuberculosis gastrointestinal 31.99 11.46 19 232621 237 42388458
Nocturia 31.97 11.46 13 232627 12099 42376596
Central nervous system vasculitis 31.93 11.46 27 232613 607 42388088
Electrocardiogram abnormal 31.90 11.46 8 232632 10137 42378558
Fluid retention 31.87 11.46 79 232561 31540 42357155
Chimerism 31.85 11.46 19 232621 239 42388456
Central nervous system lesion 31.81 11.46 105 232535 7765 42380930
Hallucination, auditory 31.76 11.46 21 232619 14843 42373852
Peritonitis 31.72 11.46 192 232448 18441 42370254
Sinus bradycardia 31.71 11.46 21 232619 14832 42373863
Diabetic cardiomyopathy 31.62 11.46 10 232630 19 42388676
Disseminated trichosporonosis 31.57 11.46 14 232626 89 42388606
Meningomyelitis herpes 31.56 11.46 11 232629 32 42388663
Zoonotic bacterial infection 31.55 11.46 13 232627 67 42388628
Soft tissue mass 31.51 11.46 33 232607 979 42387716
Large intestine perforation 31.46 11.46 119 232521 9417 42379278
Chronic hepatitis C 31.44 11.46 25 232615 514 42388181
Oral lichenoid reaction 31.37 11.46 15 232625 116 42388579
Hepatic artery aneurysm 31.35 11.46 12 232628 49 42388646
Coma 31.30 11.46 168 232472 53386 42335309
Throat irritation 31.29 11.46 16 232624 13020 42375675
Renal tuberculosis 31.28 11.46 10 232630 20 42388675
Lymphadenitis fungal 31.28 11.46 9 232631 10 42388685
Seroma 31.27 11.46 27 232613 625 42388070
Renal cell carcinoma 31.27 11.46 83 232557 5434 42383261
Second primary malignancy 31.20 11.46 7 232633 9568 42379127
Fungal sepsis 31.11 11.46 34 232606 1060 42387635
Skin discolouration 31.10 11.46 41 232599 20849 42367846
Malignant neoplasm of conjunctiva 31.07 11.46 11 232629 34 42388661
Lymphadenitis bacterial 30.97 11.46 12 232628 51 42388644
Graft ischaemia 30.83 11.46 11 232629 35 42388660
Nephritis haemorrhagic 30.82 11.46 9 232631 11 42388684
Transitional cell carcinoma metastatic 30.81 11.46 14 232626 95 42388600
Pleocytosis 30.81 11.46 27 232613 638 42388057
Myocarditis infectious 30.79 11.46 12 232628 52 42388643
Blood test abnormal 30.74 11.46 16 232624 12890 42375805
Angina unstable 30.69 11.46 12 232628 11436 42377259
Bronchospasm 30.65 11.46 16 232624 12869 42375826
Panic attack 30.58 11.46 11 232629 11034 42377661
Osteomyelitis 30.53 11.46 187 232453 18036 42370659
Hyperoxaluria 30.49 11.46 16 232624 154 42388541
Unresponsive to stimuli 30.46 11.46 80 232560 31323 42357372
Glomerulonephritis rapidly progressive 30.45 11.46 31 232609 889 42387806
Ascites 30.33 11.46 456 232184 56222 42332473
Viral test positive 30.27 11.46 18 232622 225 42388470
Perinephric abscess 29.91 11.46 12 232628 57 42388638
Plasmablastic lymphoma 29.86 11.46 26 232614 609 42388086
Uraemic encephalopathy 29.86 11.46 22 232618 402 42388293
Blister 29.86 11.46 66 232574 27424 42361271
Kidney rupture 29.84 11.46 17 232623 195 42388500
Rhinitis 29.81 11.46 14 232626 11963 42376732
Urinary incontinence 29.80 11.46 45 232595 21623 42367072
Device malfunction 29.78 11.46 15 232625 12312 42376383
Necrotising herpetic retinopathy 29.72 11.46 11 232629 40 42388655
Mood swings 29.68 11.46 6 232634 8820 42379875
Microangiopathy 29.54 11.46 41 232599 1641 42387054
Hypopnoea 29.52 11.46 4 232636 7878 42380817
Granulomatous liver disease 29.52 11.46 27 232613 676 42388019
Oral hairy leukoplakia 29.51 11.46 7 232633 0 42388695
Acanthamoeba keratitis 29.51 11.46 7 232633 0 42388695
Complications of transplanted pancreas 29.49 11.46 10 232630 26 42388669
Tremor 29.48 11.46 715 231925 96214 42292481
Pyelonephritis fungal 29.40 11.46 13 232627 82 42388613
Papule 29.40 11.46 84 232556 5742 42382953
Hyperplasia 29.26 11.46 27 232613 684 42388011
Ureteritis 29.25 11.46 15 232625 137 42388558
Acanthoma 29.23 11.46 10 232630 27 42388668
Proteus infection 29.22 11.46 37 232603 1353 42387342
Metastatic malignant melanoma 29.15 11.46 49 232591 2324 42386371
Abnormal dreams 29.15 11.46 5 232635 8266 42380429
Nervousness 29.07 11.46 19 232621 13513 42375182
No adverse event 29.02 11.46 112 232528 38909 42349786
Ventricular fibrillation 29.02 11.46 77 232563 30046 42358649
Squamous cell carcinoma of the oral cavity 28.98 11.46 19 232621 285 42388410
Biloma 28.98 11.46 14 232626 111 42388584
Periodontitis 28.97 11.46 47 232593 2164 42386531
Parvovirus B19 infection reactivation 28.96 11.46 10 232630 28 42388667
Infection 28.95 11.46 809 231831 111259 42277436
Herpes simplex oesophagitis 28.89 11.46 18 232622 246 42388449
Meningitis staphylococcal 28.89 11.46 13 232627 86 42388609
Aspiration 28.84 11.46 33 232607 17853 42370842
Tuberculosis of central nervous system 28.83 11.46 17 232623 209 42388486
Adult T-cell lymphoma/leukaemia 28.82 11.46 16 232624 174 42388521
Portal vein occlusion 28.79 11.46 12 232628 64 42388631
Pulmonary alveolar haemorrhage 28.70 11.46 158 232482 14658 42374037
Illness 28.63 11.46 58 232582 24872 42363823
Serratia infection 28.63 11.46 35 232605 1234 42387461
Injection site mass 28.48 11.46 6 232634 8569 42380126
Rib fracture 28.47 11.46 29 232611 16542 42372153
Metabolic acidosis 28.44 11.46 419 232221 51439 42337256
Sporotrichosis 28.34 11.46 12 232628 67 42388628
Anhedonia 28.33 11.46 4 232636 7636 42381059
Abdominal infection 28.30 11.46 50 232590 2469 42386226
Stomatitis 28.25 11.46 160 232480 50169 42338526
Disseminated toxoplasmosis 28.22 11.46 18 232622 257 42388438
Ageusia 28.22 11.46 14 232626 11591 42377104
Multimorbidity 28.19 11.46 30 232610 907 42387788
Granulomatous dermatitis 28.15 11.46 19 232621 300 42388395
Multiple sclerosis 28.12 11.46 4 232636 7594 42381101
Shock 27.91 11.46 262 232378 28859 42359836
Acute pulmonary histoplasmosis 27.90 11.46 16 232624 186 42388509
Petechiae 27.87 11.46 11 232629 10424 42378271
Skin mass 27.85 11.46 73 232567 4743 42383952
Back disorder 27.71 11.46 4 232636 7510 42381185
Extranodal marginal zone B-cell lymphoma (MALT type) 27.67 11.46 19 232621 309 42388386
Eye infection toxoplasmal 27.67 11.46 19 232621 309 42388386
Phaeohyphomycotic brain abscess 27.63 11.46 11 232629 51 42388644
Human herpes virus 8 test positive 27.53 11.46 10 232630 34 42388661
Human T-cell lymphotropic virus type I infection 27.53 11.46 10 232630 34 42388661
Knee arthroplasty 27.47 11.46 7 232633 8774 42379921
Serum sickness 27.41 11.46 46 232594 2179 42386516
Crystal nephropathy 27.40 11.46 25 232615 624 42388071
Hepatosplenomegaly 27.32 11.46 71 232569 4589 42384106
Asphyxia 27.30 11.46 6 232634 8320 42380375
Therapy non-responder 27.28 11.46 426 232214 52933 42335762
Diffuse alveolar damage 27.27 11.46 50 232590 2542 42386153
Cytomegalovirus gastrointestinal ulcer 27.24 11.46 13 232627 100 42388595
Oedema 27.24 11.46 169 232471 51832 42336863
Giardiasis 27.17 11.46 23 232617 518 42388177
Eye infection fungal 27.15 11.46 22 232618 465 42388230
Diffuse mesangial sclerosis 27.13 11.46 11 232629 54 42388641
Haemodynamic instability 27.13 11.46 138 232502 12419 42376276
Cholangitis sclerosing 27.08 11.46 42 232598 1860 42386835
Burkholderia cepacia complex sepsis 27.03 11.46 7 232633 3 42388692
Endocarditis enterococcal 27.03 11.46 13 232627 102 42388593
Dementia 27.02 11.46 30 232610 16450 42372245
Pneumonia viral 27.02 11.46 67 232573 4207 42384488
Musculoskeletal discomfort 26.99 11.46 9 232631 9467 42379228
Limb injury 26.98 11.46 23 232617 14282 42374413
Obesity 26.94 11.46 30 232610 16429 42372266
Central nervous system immune reconstitution inflammatory response 26.93 11.46 9 232631 22 42388673
Pneumonia staphylococcal 26.91 11.46 59 232581 3417 42385278
Pericarditis constrictive 26.80 11.46 23 232617 528 42388167
Brain herniation 26.77 11.46 72 232568 4751 42383944
Respiratory tract inflammation 26.73 11.46 21 232619 424 42388271
Acute coronary syndrome 26.71 11.46 25 232615 14840 42373855
Arterial rupture 26.66 11.46 23 232617 532 42388163
Hepatitis B 26.65 11.46 89 232551 6622 42382073
Acute generalised exanthematous pustulosis 26.60 11.46 7 232633 8588 42380107
Renal abscess 26.48 11.46 20 232620 380 42388315
Hepatic vein stenosis 26.37 11.46 7 232633 4 42388691
Encephalitis autoimmune 26.36 11.46 35 232605 1342 42387353
Photosensitivity reaction 26.34 11.46 138 232502 12564 42376131
Delirium 26.32 11.46 173 232467 52346 42336349
Gastritis fungal 26.22 11.46 14 232626 140 42388555
Osteomyelitis chronic 26.22 11.46 19 232621 338 42388357
Glomerulonephritis minimal lesion 26.21 11.46 25 232615 661 42388034
Lymphocytic infiltration 26.21 11.46 29 232611 917 42387778
Metastases to skin 26.19 11.46 23 232617 545 42388150
Tuberculosis 26.19 11.46 117 232523 9982 42378713
Drug level below therapeutic 26.17 11.46 87 232553 6458 42382237
Tumour lysis syndrome 26.15 11.46 51 232589 22180 42366515
Gingival pain 26.13 11.46 7 232633 8487 42380208
Portal hypertension 26.11 11.46 71 232569 4716 42383979
Cyclosporidium infection 26.08 11.46 8 232632 13 42388682
Schistocytosis 26.08 11.46 8 232632 13 42388682
Hepatitis B reactivation 26.08 11.46 69 232571 4509 42384186
Corneal endotheliitis 26.04 11.46 11 232629 61 42388634
Retroperitoneal abscess 26.03 11.46 19 232621 342 42388353
Bone tuberculosis 25.76 11.46 21 232619 448 42388247
Meningitis bacterial 25.73 11.46 35 232605 1374 42387321
Lymph node tuberculosis 25.64 11.46 22 232618 505 42388190
Superinfection viral 25.62 11.46 9 232631 27 42388668
Biphasic mesothelioma 25.61 11.46 11 232629 64 42388631
Central nervous system abscess 25.54 11.46 10 232630 44 42388651
Emphysematous cholecystitis 25.52 11.46 12 232628 89 42388606
Nephrosclerosis 25.46 11.46 30 232610 1017 42387678
Body temperature increased 25.45 11.46 45 232595 20313 42368382
Keratouveitis 25.37 11.46 9 232631 28 42388667
Prescribed overdose 25.35 11.46 20 232620 12907 42375788
Apoptosis 25.34 11.46 23 232617 570 42388125
Immunosuppressant drug level 25.30 11.46 6 232634 0 42388695
Diarrhoea haemorrhagic 25.28 11.46 96 232544 7611 42381084
Productive cough 25.28 11.46 171 232469 51396 42337299
Chemical peritonitis 25.23 11.46 13 232627 120 42388575
Pathergy reaction 25.21 11.46 7 232633 6 42388689
Drug intolerance 25.20 11.46 299 232341 80125 42308570
Herpes simplex test positive 25.17 11.46 16 232624 227 42388468
Renal and pancreas transplant rejection 25.14 11.46 9 232631 29 42388666
Renal cortical necrosis 25.05 11.46 15 232625 190 42388505
Cutaneous tuberculosis 25.05 11.46 13 232627 122 42388573
Mucosal hypertrophy 25.01 11.46 10 232630 47 42388648
Sputum discoloured 24.97 11.46 12 232628 10120 42378575
Influenza 24.92 11.46 218 232422 61957 42326738
Red blood cell count decreased 24.91 11.46 93 232547 32622 42356073
Myelitis 24.89 11.46 30 232610 1042 42387653
Metastasis 24.88 11.46 69 232571 4636 42384059
Acute hepatitis C 24.87 11.46 13 232627 124 42388571
Hyperparathyroidism 24.84 11.46 33 232607 1266 42387429
Euphoric mood 24.84 11.46 3 232637 6450 42382245
Bladder cancer 24.83 11.46 34 232606 17013 42371682
Gastrointestinal toxicity 24.76 11.46 62 232578 3917 42384778
Endothelial dysfunction 24.75 11.46 12 232628 96 42388599
Extrapulmonary tuberculosis 24.69 11.46 14 232626 159 42388536
Mycobacterial peritonitis 24.69 11.46 14 232626 159 42388536
Eosinophil count increased 24.67 11.46 14 232626 10749 42377946
Metastatic carcinoma of the bladder 24.64 11.46 16 232624 236 42388459
Rash maculo-papular 24.58 11.46 113 232527 37390 42351305
C-reactive protein increased 24.53 11.46 225 232415 63335 42325360
Blood pressure diastolic decreased 24.50 11.46 13 232627 10362 42378333
Systemic bacterial infection 24.47 11.46 9 232631 32 42388663
Portal fibrosis 24.47 11.46 18 232622 328 42388367
Disseminated coccidioidomycosis 24.44 11.46 12 232628 99 42388596
Diabetic ketoacidosis 24.40 11.46 207 232433 22160 42366535
Erythema multiforme 24.31 11.46 12 232628 9965 42378730
Respiratory tract infection fungal 24.25 11.46 26 232614 793 42387902
Ill-defined disorder 24.24 11.46 32 232608 16264 42372431
Renal cyst haemorrhage 24.22 11.46 24 232616 666 42388029
Rectal prolapse 24.21 11.46 22 232618 546 42388149
Viral vasculitis 24.13 11.46 12 232628 102 42388593
Coordination abnormal 24.08 11.46 7 232633 8043 42380652
Hepatitis viral 23.99 11.46 26 232614 803 42387892
Gastric disorder 23.95 11.46 18 232622 11904 42376791
Eye swelling 23.94 11.46 18 232622 11902 42376793
Hyperparathyroidism secondary 23.92 11.46 39 232601 1803 42386892
Device related infection 23.90 11.46 191 232449 20088 42368607
Hepatitis C virus test 23.89 11.46 10 232630 54 42388641
Activated partial thromboplastin time prolonged 23.89 11.46 31 232609 15872 42372823
Staphylococcal scalded skin syndrome 23.83 11.46 18 232622 342 42388353
Hypophosphataemia 23.82 11.46 49 232591 20896 42367799
Herpes simplex meningomyelitis 23.78 11.46 7 232633 9 42388686
Peripheral coldness 23.77 11.46 8 232632 8367 42380328
Chronic papillomatous dermatitis 23.74 11.46 10 232630 55 42388640
Gastrointestinal ulcer perforation 23.74 11.46 10 232630 55 42388640
Cytomegalovirus mucocutaneous ulcer 23.69 11.46 11 232629 79 42388616
Splenic infection viral 23.66 11.46 9 232631 36 42388659
Haemorrhage 23.54 11.46 214 232426 60349 42328346
Skin angiosarcoma 23.54 11.46 8 232632 21 42388674
Giant cell myocarditis 23.54 11.46 8 232632 21 42388674
Hidradenocarcinoma 23.54 11.46 8 232632 21 42388674
Hypocalcaemia 23.49 11.46 85 232555 30088 42358607
Epiploic appendagitis 23.45 11.46 10 232630 57 42388638
Pyuria 23.42 11.46 28 232612 964 42387731
Thrombotic thrombocytopenic purpura 23.38 11.46 59 232581 3745 42384950
Face oedema 23.38 11.46 24 232616 13642 42375053
Acinetobacter sepsis 23.36 11.46 12 232628 110 42388585
Post infection glomerulonephritis 23.36 11.46 12 232628 110 42388585
Disseminated varicella 23.36 11.46 7 232633 10 42388685
Ankylosing spondylitis 23.31 11.46 5 232635 7051 42381644
Sphincter of Oddi dysfunction 23.29 11.46 15 232625 218 42388477
CEC syndrome 23.28 11.46 8 232632 22 42388673
Streptococcal bacteraemia 23.15 11.46 48 232592 2674 42386021
Acinetobacter bacteraemia 23.14 11.46 14 232626 181 42388514
Blood immunoglobulin M decreased 23.05 11.46 26 232614 840 42387855
Systemic lupus erythematosus 23.05 11.46 11 232629 9313 42379382
Pancreas transplant 23.02 11.46 8 232632 23 42388672
Infected lymphocele 23.02 11.46 8 232632 23 42388672
Cholelithiasis 23.01 11.46 59 232581 23287 42365408
Microtia 23 11.46 16 232624 266 42388429
Mental impairment 22.99 11.46 20 232620 12297 42376398
Arterial fibrosis 22.96 11.46 7 232633 11 42388684
Pericardial cyst 22.96 11.46 7 232633 11 42388684
Glomerulonephropathy 22.94 11.46 15 232625 224 42388471
Gastrointestinal haemorrhage 22.93 11.46 385 232255 97341 42291354
Pneumonia legionella 22.92 11.46 43 232597 2225 42386470
Pharyngeal oedema 22.92 11.46 3 232637 6065 42382630
Sinus tachycardia 22.91 11.46 49 232591 20604 42368091
Retinitis 22.81 11.46 20 232620 473 42388222
Roseolovirus test positive 22.79 11.46 11 232629 87 42388608
Rhabdoid tumour 22.77 11.46 8 232632 24 42388671
Parasitic gastroenteritis 22.75 11.46 13 232627 150 42388545
Ocular lymphoma 22.69 11.46 11 232629 88 42388607
Hantaviral infection 22.59 11.46 7 232633 12 42388683
Cryoglobulinaemia 22.53 11.46 21 232619 539 42388156
Benign prostatic hyperplasia 22.49 11.46 51 232589 21001 42367694
Hepatitis infectious mononucleosis 22.48 11.46 11 232629 90 42388605
Metastases to lymph nodes 22.46 11.46 78 232562 5920 42382775
Myelitis transverse 22.42 11.46 32 232608 1315 42387380
Gastrinoma 22.39 11.46 9 232631 43 42388652
Seasonal allergy 22.34 11.46 8 232632 8047 42380648
Pneumonia 22.24 11.46 1993 230647 420156 41968539
Gastroenteritis 22.24 11.46 160 232480 16289 42372406
Ureteric anastomosis complication 22.23 11.46 9 232631 44 42388651
Propionibacterium infection 22.21 11.46 15 232625 237 42388458
Chromaturia 22.19 11.46 33 232607 15956 42372739
Herpes oesophagitis 22.17 11.46 13 232627 158 42388537
Blood glucose decreased 22.11 11.46 27 232613 14192 42374503
Gastrointestinal injury 22.08 11.46 29 232611 1100 42387595
Hyperglycaemic hyperosmolar nonketotic syndrome 22.03 11.46 35 232605 1583 42387112
Sexual dysfunction 21.98 11.46 5 232635 6770 42381925
Immunosuppression 21.97 11.46 98 232542 8355 42380340
Abdominal wall haemorrhage 21.96 11.46 20 232620 498 42388197
Haemoperitoneum 21.92 11.46 40 232600 2026 42386669
Parametritis 21.90 11.46 7 232633 14 42388681
Bronchial anastomosis complication 21.90 11.46 7 232633 14 42388681
Blood creatinine abnormal 21.87 11.46 51 232589 3078 42385617
Rebound effect 21.85 11.46 89 232551 7290 42381405
Type III immune complex mediated reaction 21.84 11.46 21 232619 561 42388134
Choking 21.77 11.46 4 232636 6294 42382401
Pancreatitis haemorrhagic 21.77 11.46 18 232622 392 42388303
Peritonitis bacterial 21.75 11.46 85 232555 6830 42381865
Tooth disorder 21.70 11.46 20 232620 11959 42376736
Incision site pain 21.68 11.46 38 232602 1865 42386830
Sebaceous hyperplasia 21.65 11.46 12 232628 130 42388565
Product administration error 21.64 11.46 42 232598 18301 42370394
Microsporum infection 21.64 11.46 8 232632 29 42388666
Pneumonitis 21.63 11.46 136 232504 41582 42347113
Potentiating drug interaction 21.58 11.46 81 232559 6387 42382308
Bordetella infection 21.49 11.46 13 232627 168 42388527
Trichophytic granuloma 21.44 11.46 9 232631 49 42388646
Obstructive nephropathy 21.44 11.46 9 232631 49 42388646
Hyperparathyroidism tertiary 21.44 11.46 9 232631 49 42388646
Cow pox 21.43 11.46 8 232632 30 42388665
Pleural adhesion 21.30 11.46 14 232626 211 42388484
Transmission of an infectious agent via transplant 21.27 11.46 7 232633 16 42388679
Ventricular extrasystoles 21.27 11.46 25 232615 13365 42375330
Wound 21.25 11.46 38 232602 17079 42371616
Hepatitis cholestatic 21.25 11.46 108 232532 9716 42378979
Mycobacterium kansasii infection 21.24 11.46 17 232623 353 42388342
Lymphangiectasia 21.23 11.46 8 232632 31 42388664
Penile ulceration 21.22 11.46 24 232616 778 42387917
Cardiac valve vegetation 21.21 11.46 20 232620 521 42388174
Steatohepatitis 21.16 11.46 19 232621 464 42388231
Bile output increased 21.08 11.46 5 232635 0 42388695
Eating disorder 21.07 11.46 14 232626 9871 42378824
Metapneumovirus pneumonia 21.06 11.46 10 232630 76 42388619
Wound infection fungal 21.03 11.46 8 232632 32 42388663
Labelled drug-drug interaction issue 21.00 11.46 36 232604 1735 42386960
Immune-mediated enterocolitis 20.98 11.46 3 232637 5674 42383021
Q fever 20.96 11.46 12 232628 139 42388556
Neutrophil morphology abnormal 20.95 11.46 10 232630 77 42388618
Myoclonic dystonia 20.95 11.46 10 232630 77 42388618
Limbic encephalitis 20.95 11.46 18 232622 414 42388281
Red cell distribution width increased 20.94 11.46 6 232634 6958 42381737
Bacillus infection 20.90 11.46 23 232617 723 42387972
Renal cyst infection 20.86 11.46 11 232629 107 42388588
Muscle rigidity 20.84 11.46 21 232619 12038 42376657
Lip squamous cell carcinoma 20.82 11.46 12 232628 141 42388554
Surgical procedure repeated 20.80 11.46 17 232623 364 42388331
Gastrointestinal tract adenoma 20.79 11.46 16 232624 313 42388382
Ischaemic cardiomyopathy 20.79 11.46 5 232635 6517 42382178
Respiratory symptom 20.77 11.46 18 232622 11088 42377607
Vascular graft complication 20.74 11.46 12 232628 142 42388553
Pulmonary air leakage 20.74 11.46 14 232626 221 42388474
Enteritis 20.72 11.46 115 232525 10701 42377994
Movement disorder 20.72 11.46 30 232610 14668 42374027
Blood uric acid increased 20.70 11.46 33 232607 15514 42373181
Genitourinary tract infection 20.69 11.46 11 232629 109 42388586
Sinus disorder 20.67 11.46 9 232631 8041 42380654
Chest wall abscess 20.64 11.46 14 232626 223 42388472
Accidental overdose 20.63 11.46 82 232558 28248 42360447
Gout 20.56 11.46 81 232559 27974 42360721
Chronic myelomonocytic leukaemia 20.47 11.46 23 232617 740 42387955
Gastric ulcer haemorrhage, obstructive 20.43 11.46 7 232633 19 42388676
Acute disseminated encephalomyelitis 20.39 11.46 12 232628 147 42388548
Sinusitis bacterial 20.39 11.46 20 232620 548 42388147
Blood creatine increased 20.38 11.46 73 232567 5627 42383068
Burkitt's lymphoma 20.35 11.46 11 232629 113 42388582
Pneumonia adenoviral 20.34 11.46 17 232623 376 42388319
Spindle cell sarcoma 20.32 11.46 12 232628 148 42388547
Immune-mediated adverse reaction 20.29 11.46 26 232614 962 42387733
Seroconversion test negative 20.26 11.46 6 232634 8 42388687
Cytomegalovirus myocarditis 20.26 11.46 6 232634 8 42388687
Erythropoiesis abnormal 20.20 11.46 16 232624 327 42388368
Dystonia 20.19 11.46 24 232616 12766 42375929
Cataract 20.18 11.46 92 232548 30512 42358183
Cardiac murmur 20.14 11.46 24 232616 12751 42375944
Hyperaesthesia 20.11 11.46 4 232636 5948 42382747
Tonsillar hypertrophy 20.04 11.46 25 232615 900 42387795
Anaemia 19.99 11.46 1290 231350 278988 42109707
Treatment failure 19.96 11.46 465 232175 62159 42326536
Obsessive-compulsive disorder 19.92 11.46 6 232634 6737 42381958
Argentine haemorrhagic fever 19.92 11.46 7 232633 21 42388674
Rabies 19.85 11.46 6 232634 9 42388686
Lymphangitis 19.84 11.46 21 232619 631 42388064
Prostatitis 19.82 11.46 77 232563 6171 42382524
Phospholipidosis 19.82 11.46 9 232631 61 42388634
Lactic acidosis 19.81 11.46 155 232485 45106 42343589
Renal haematoma 19.78 11.46 21 232619 633 42388062
Acute respiratory failure 19.77 11.46 310 232330 38548 42350147
Human herpesvirus 6 infection reactivation 19.73 11.46 18 232622 449 42388246
Device dislocation 19.72 11.46 9 232631 7822 42380873
Wound infection pseudomonas 19.72 11.46 16 232624 339 42388356
Sudden death 19.69 11.46 38 232602 16591 42372104
Adenovirus test positive 19.63 11.46 10 232630 90 42388605
Schistosomiasis 19.61 11.46 8 232632 40 42388655
Joint stiffness 19.58 11.46 23 232617 12299 42376396
Biliary ischaemia 19.53 11.46 10 232630 91 42388604
Nephrocalcinosis 19.51 11.46 23 232617 780 42387915
Orchitis 19.50 11.46 40 232600 2211 42386484
Intervertebral disc protrusion 19.45 11.46 19 232621 11053 42377642
Mesangioproliferative glomerulonephritis 19.45 11.46 12 232628 161 42388534
Cellulitis orbital 19.41 11.46 18 232622 459 42388236
Gynaecomastia 19.40 11.46 24 232616 12543 42376152
Tongue necrosis 19.30 11.46 8 232632 42 42388653
Polyneuropathy 19.30 11.46 46 232594 18615 42370080
Mood altered 19.29 11.46 18 232622 10700 42377995
Thirst 19.28 11.46 13 232627 9095 42379600
Platelet count increased 19.23 11.46 18 232622 10685 42378010
Melaena 19.23 11.46 128 232512 38618 42350077
Epstein-Barr virus antibody positive 19.21 11.46 15 232625 300 42388395
Pre-engraftment immune reaction 19.20 11.46 12 232628 165 42388530
Eschar 19.11 11.46 22 232618 727 42387968
Pericarditis infective 19.11 11.46 9 232631 67 42388628
Evans syndrome 19.01 11.46 17 232623 413 42388282
Cutaneous leishmaniasis 18.99 11.46 14 232626 256 42388439
Hypertensive emergency 18.97 11.46 29 232611 1268 42387427
Renal vessel disorder 18.95 11.46 13 232627 211 42388484
Cryptococcal fungaemia 18.95 11.46 12 232628 169 42388526
Blood pressure abnormal 18.94 11.46 16 232624 9982 42378713
Pulmonary cavitation 18.86 11.46 29 232611 1275 42387420
Skin infection 18.82 11.46 101 232539 9279 42379416
Pneumonia influenzal 18.79 11.46 36 232604 1893 42386802
Extra-axial haemorrhage 18.77 11.46 6 232634 12 42388683
Bundle branch block left 18.71 11.46 6 232634 6470 42382225
Bronchostenosis 18.71 11.46 17 232623 422 42388273
T-cell lymphoma 18.62 11.46 27 232613 1126 42387569
Hepatic haematoma 18.61 11.46 17 232623 425 42388270
Cardiomyopathy 18.58 11.46 49 232591 19161 42369534
Cholestasis 18.55 11.46 267 232373 32612 42356083
Viral skin infection 18.42 11.46 8 232632 48 42388647
Renal necrosis 18.42 11.46 12 232628 178 42388517
Skin plaque 18.39 11.46 72 232568 5791 42382904
Gastroenteritis eosinophilic 18.34 11.46 13 232627 223 42388472
Mycotic endophthalmitis 18.34 11.46 13 232627 223 42388472
Lung disorder 18.34 11.46 170 232470 47753 42340942
Capnocytophaga infection 18.33 11.46 11 232629 140 42388555
Decreased activity 18.33 11.46 3 232637 5132 42383563
Lip ulceration 18.31 11.46 25 232615 985 42387710
Lymphorrhoea 18.25 11.46 9 232631 75 42388620
Dehiscence 18.24 11.46 20 232620 626 42388069
Middle insomnia 18.23 11.46 10 232630 7823 42380872
Wound infection 18.22 11.46 92 232548 8254 42380441
Granulocytopenia 18.19 11.46 8 232632 7106 42381589
Leukoencephalopathy 18.18 11.46 64 232576 4890 42383805
Disorientation 18.17 11.46 120 232520 36269 42352426
Splenic vein thrombosis 18.16 11.46 19 232621 563 42388132
Alopecia 18.14 11.46 90 232550 29186 42359509
Latent autoimmune diabetes in adults 18.13 11.46 11 232629 143 42388552
Gingival bleeding 18.11 11.46 12 232628 8473 42380222
Oesophageal squamous cell carcinoma 18.09 11.46 16 232624 383 42388312
Paradoxical drug reaction 18.08 11.46 62 232578 4676 42384019
Vena cava injury 18.05 11.46 15 232625 329 42388366
Rotavirus infection 18.03 11.46 18 232622 504 42388191
Hiccups 18.00 11.46 24 232616 12147 42376548
Stenotrophomonas bacteraemia 18.00 11.46 11 232629 145 42388550
Sinusitis 17.99 11.46 168 232472 47124 42341571
Blood calcium increased 17.99 11.46 12 232628 8442 42380253
Gingivitis ulcerative 17.95 11.46 13 232627 231 42388464
Arteriovenous fistula thrombosis 17.94 11.46 15 232625 332 42388363
Alpha haemolytic streptococcal infection 17.92 11.46 35 232605 1867 42386828
Restrictive pulmonary disease 17.89 11.46 29 232611 1334 42387361
Lymphadenopathy mediastinal 17.89 11.46 48 232592 3163 42385532
Respiratory papilloma 17.86 11.46 6 232634 15 42388680
Genital disorder 17.86 11.46 6 232634 15 42388680
Leuconostoc infection 17.86 11.46 6 232634 15 42388680
Encephalitis protozoal 17.84 11.46 7 232633 31 42388664
Hemianopia heteronymous 17.84 11.46 7 232633 31 42388664
Complications of bone marrow transplant 17.81 11.46 13 232627 234 42388461
Musculoskeletal chest pain 17.71 11.46 21 232619 11183 42377512
Paraspinal abscess 17.66 11.46 9 232631 81 42388614
Membranous-like glomerulopathy with masked IgG-kappa deposits 17.64 11.46 5 232635 5 42388690
Epithelioid mesothelioma 17.64 11.46 5 232635 5 42388690
Pseudohypoaldosteronism 17.64 11.46 5 232635 5 42388690
Bone marrow transplant 17.64 11.46 27 232613 1182 42387513
Toxic encephalopathy 17.61 11.46 80 232560 6873 42381822
Pyogenic granuloma 17.60 11.46 14 232626 288 42388407
Pemphigoid 17.59 11.46 22 232618 11445 42377250
Acquired porokeratosis 17.59 11.46 6 232634 16 42388679
Meningitis histoplasma 17.59 11.46 6 232634 16 42388679
Lipase increased 17.58 11.46 19 232621 10547 42378148
Cell-mediated immune deficiency 17.57 11.46 9 232631 82 42388613
Escherichia sepsis 17.56 11.46 70 232570 5677 42383018
Oedematous kidney 17.52 11.46 8 232632 55 42388640
Citrobacter infection 17.52 11.46 20 232620 655 42388040
Rotator cuff syndrome 17.50 11.46 7 232633 6579 42382116
Normocytic anaemia 17.50 11.46 51 232589 3526 42385169
Haematocrit decreased 17.49 11.46 115 232525 34793 42353902
Cerebral cyst 17.48 11.46 14 232626 291 42388404
Pleural effusion 17.47 11.46 672 231968 96494 42292201
Gallbladder disorder 17.47 11.46 9 232631 7293 42381402
Autoimmune anaemia 17.33 11.46 6 232634 17 42388678
Symptom recurrence 17.29 11.46 30 232610 1460 42387235
Malassezia infection 17.28 11.46 8 232632 57 42388638
Cell death 17.26 11.46 45 232595 2914 42385781
Abdominal abscess 17.17 11.46 64 232576 5029 42383666
Fluoride increased 17.16 11.46 8 232632 58 42388637
Graft haemorrhage 17.16 11.46 8 232632 58 42388637
Sebaceous gland disorder 17.16 11.46 7 232633 35 42388660
Vascular anastomotic haemorrhage 17.16 11.46 14 232626 299 42388396
Delusion 17.16 11.46 34 232606 14700 42373995
Diarrhoea 17.15 11.46 2229 230411 458620 41930075
Neoplasm malignant 17.09 11.46 65 232575 22678 42366017
Intestinal ulcer 17.07 11.46 25 232615 1052 42387643
Femur fracture 17.05 11.46 17 232623 9795 42378900
SARS-CoV-2 RNA increased 17.05 11.46 8 232632 59 42388636
Injection site rash 17.03 11.46 5 232635 5707 42382988
Hypertriglyceridaemia 17.02 11.46 104 232536 10022 42378673
Gastric perforation 16.99 11.46 46 232594 3047 42385648
Incisional hernia 16.99 11.46 29 232611 1393 42387302
Hepatic infection 16.99 11.46 21 232619 749 42387946
Incontinence 16.97 11.46 8 232632 6822 42381873
Eyelid oedema 16.95 11.46 5 232635 5690 42383005
Muscle spasticity 16.94 11.46 8 232632 6814 42381881
Pneumonia pneumococcal 16.89 11.46 41 232599 2540 42386155
Cerebral ventricle collapse 16.89 11.46 10 232630 124 42388571
Interferon gamma decreased 16.86 11.46 4 232636 0 42388695
Cystitis glandularis 16.86 11.46 4 232636 0 42388695
Sarcomatoid carcinoma 16.86 11.46 4 232636 0 42388695
Clostridial infection 16.85 11.46 53 232587 3821 42384874
Renal adenoma 16.85 11.46 7 232633 37 42388658
Bradyphrenia 16.84 11.46 4 232636 5258 42383437
Soft tissue infection 16.80 11.46 42 232598 2651 42386044
Quadriplegia 16.80 11.46 37 232603 2150 42386545
Hyperthyroidism 16.78 11.46 33 232607 14308 42374387
Pneumonia mycoplasmal 16.77 11.46 21 232619 759 42387936
Sinus node dysfunction 16.76 11.46 3 232637 4809 42383886
Milk allergy 16.75 11.46 10 232630 126 42388569
High grade B-cell lymphoma Burkitt-like lymphoma stage IV 16.74 11.46 5 232635 7 42388688
Small intestine gangrene 16.74 11.46 5 232635 7 42388688
Muscle neoplasm 16.74 11.46 5 232635 7 42388688
Priapism 16.71 11.46 7 232633 6400 42382295
Acute allograft nephropathy 16.70 11.46 7 232633 38 42388657
Injection site pruritus 16.69 11.46 16 232624 9389 42379306
IIIrd nerve paralysis 16.68 11.46 18 232622 553 42388142
Crying 16.66 11.46 7 232633 6387 42382308
Muscle twitching 16.65 11.46 24 232616 11756 42376939
Abscess soft tissue 16.61 11.46 10 232630 128 42388567
Spinal cord abscess 16.56 11.46 16 232624 430 42388265
Viral sepsis 16.55 11.46 10 232630 129 42388566
Ureteric dilatation 16.53 11.46 12 232628 214 42388481
Granulomatous lymphadenitis 16.53 11.46 12 232628 214 42388481
Left ventricular hypertrophy 16.49 11.46 97 232543 9222 42379473
Deafness 16.47 11.46 29 232611 13111 42375584
Hyperthermia 16.45 11.46 27 232613 12547 42376148
Product storage error 16.44 11.46 22 232618 11118 42377577
Segmented hyalinising vasculitis 16.40 11.46 7 232633 40 42388655
Affective disorder 16.39 11.46 6 232634 5954 42382741
Pneumonia proteus 16.35 11.46 5 232635 8 42388687
Hyperglycaemia 16.34 11.46 346 232294 45513 42343182
Coeliac disease 16.34 11.46 23 232617 933 42387762
Blood lactic acid increased 16.32 11.46 12 232628 8027 42380668
Bile duct necrosis 16.29 11.46 8 232632 66 42388629
Infective tenosynovitis 16.28 11.46 9 232631 97 42388598
Throat tightness 16.26 11.46 17 232623 9582 42379113
Respiratory tract congestion 16.20 11.46 11 232629 7667 42381028
Blood pressure systolic abnormal 16.19 11.46 5 232635 5523 42383172
Lemierre syndrome 16.17 11.46 6 232634 22 42388673
Eosinophilia 16.17 11.46 109 232531 32790 42355905
Incoherent 16.15 11.46 3 232637 4682 42384013
Endocarditis staphylococcal 16.12 11.46 20 232620 716 42387979
Localised infection 16.12 11.46 57 232583 20316 42368379
Hernial eventration 16.09 11.46 8 232632 68 42388627
Dyslipidaemia 16.00 11.46 97 232543 9321 42379374
Cardiac autonomic neuropathy 15.99 11.46 8 232632 69 42388626
Restrictive allograft syndrome 15.97 11.46 6 232634 23 42388672
Brucellosis 15.97 11.46 6 232634 23 42388672
Herpes simplex meningoencephalitis 15.97 11.46 6 232634 23 42388672
SARS-CoV-2 antibody test positive 15.96 11.46 15 232625 389 42388306
Foot deformity 15.93 11.46 4 232636 5064 42383631
Oesophageal candidiasis 15.92 11.46 67 232573 5568 42383127
Spinal fracture 15.88 11.46 16 232624 9174 42379521
Dialysis 15.86 11.46 116 232524 11870 42376825
Atrial septal defect 15.85 11.46 12 232628 7907 42380788
Fear 15.84 11.46 22 232618 10943 42377752
Pericardial effusion 15.84 11.46 236 232404 29039 42359656
Polyp 15.80 11.46 3 232637 4611 42384084
Red blood cell schistocytes present 15.80 11.46 14 232626 336 42388359
Radiculitis brachial 15.77 11.46 6 232634 24 42388671
Immune effector cell-associated neurotoxicity syndrome 15.76 11.46 17 232623 9444 42379251
Procedural pneumothorax 15.72 11.46 7 232633 45 42388650
Nephritis 15.72 11.46 51 232589 3738 42384957
Internal haemorrhage 15.70 11.46 5 232635 5416 42383279
Pseudomonal sepsis 15.69 11.46 55 232585 4194 42384501
Myeloma cast nephropathy 15.67 11.46 9 232631 105 42388590
Duodenitis 15.65 11.46 66 232574 5490 42383205
Hyperviscosity syndrome 15.61 11.46 13 232627 286 42388409
Meningitis Escherichia 15.58 11.46 6 232634 25 42388670
Dermatitis allergic 15.56 11.46 14 232626 8469 42380226
Blood urine present 15.53 11.46 25 232615 11708 42376987
Nosocomial infection 15.49 11.46 28 232612 1408 42387287
Bacteriuria 15.46 11.46 13 232627 290 42388405
Urine output decreased 15.42 11.46 107 232533 10766 42377929
Schizophrenia 15.40 11.46 21 232619 10529 42378166
Pneumococcal infection 15.38 11.46 17 232623 537 42388158
Dizziness postural 15.36 11.46 12 232628 7783 42380912
Myocarditis mycotic 15.35 11.46 7 232633 48 42388647
Cutaneous sporotrichosis 15.35 11.46 7 232633 48 42388647
Biliary anastomosis 15.33 11.46 5 232635 11 42388684
Fracture 15.31 11.46 13 232627 8090 42380605
Drug level abnormal 15.31 11.46 13 232627 294 42388401
Haemolytic anaemia 15.28 11.46 116 232524 12011 42376684
Intraductal papillary mucinous neoplasm 15.27 11.46 16 232624 475 42388220
Acidosis 15.21 11.46 117 232523 12162 42376533
Splenic rupture 15.14 11.46 30 232610 1617 42387078
Foetal growth restriction 15.07 11.46 63 232577 5220 42383475
Metastases to peritoneum 15.07 11.46 38 232602 2411 42386284
Fungal peritonitis 15.07 11.46 22 232618 923 42387772
Retinal ischaemia 15.05 11.46 16 232624 483 42388212
Laryngeal mass 15.04 11.46 6 232634 28 42388667
Angioimmunoblastic T-cell lymphoma 15.03 11.46 14 232626 359 42388336
Oesophageal tuberculosis 15.03 11.46 5 232635 12 42388683
Cryptococcal meningoencephalitis 15.02 11.46 11 232629 199 42388496
Tuberculosis of genitourinary system 14.98 11.46 8 232632 80 42388615
Varicella zoster pneumonia 14.96 11.46 12 232628 250 42388445
Stem cell transplant 14.94 11.46 40 232600 2632 42386063
Viral load increased 14.92 11.46 43 232597 2954 42385741
Metapneumovirus infection 14.91 11.46 25 232615 1183 42387512
Bladder transitional cell carcinoma 14.91 11.46 40 232600 2636 42386059
Oligoarthritis 14.88 11.46 11 232629 202 42388493
NPM1 gene mutation 14.83 11.46 9 232631 117 42388578
Scrotal cellulitis 14.81 11.46 8 232632 82 42388613
Pneumonia herpes viral 14.77 11.46 9 232631 118 42388577
Vanishing bile duct syndrome 14.76 11.46 32 232608 1839 42386856
Septic arthritis streptococcal 14.75 11.46 5 232635 13 42388682
Psychotic disorder 14.74 11.46 96 232544 29112 42359583
Weight fluctuation 14.74 11.46 7 232633 5944 42382751
Metastases to central nervous system 14.73 11.46 21 232619 10334 42378361
Sinus congestion 14.73 11.46 10 232630 6970 42381725
Bacterial translocation 14.71 11.46 18 232622 635 42388060
Cytomegalovirus syndrome 14.70 11.46 9 232631 119 42388576
Hiatus hernia 14.68 11.46 15 232625 8545 42380150
Metastases to diaphragm 14.64 11.46 4 232636 3 42388692
Balamuthia infection 14.64 11.46 4 232636 3 42388692
Histiocytic sarcoma 14.64 11.46 4 232636 3 42388692
Granulicatella infection 14.64 11.46 4 232636 3 42388692
Temperature intolerance 14.63 11.46 4 232636 4784 42383911
Antineutrophil cytoplasmic antibody positive 14.61 11.46 3 232637 4362 42384333
Head discomfort 14.60 11.46 5 232635 5172 42383523
Erosive duodenitis 14.58 11.46 31 232609 1758 42386937
Conjunctivitis allergic 14.57 11.46 7 232633 5904 42382791
Metastases to retroperitoneum 14.56 11.46 12 232628 260 42388435
Mouth haemorrhage 14.56 11.46 8 232632 6253 42382442
Hypoaesthesia oral 14.56 11.46 4 232636 4769 42383926
Cardiac arrest 14.55 11.46 470 232170 108850 42279845
Toothache 14.53 11.46 12 232628 7571 42381124
Carpal tunnel syndrome 14.53 11.46 6 232634 5533 42383162
Hospice care 14.51 11.46 15 232625 8498 42380197
Gastroenteritis rotavirus 14.50 11.46 13 232627 317 42388378
T-cell lymphoma stage IV 14.49 11.46 10 232630 164 42388531
Ocular hyperaemia 14.49 11.46 42 232598 15921 42372774
Oral papilloma 14.48 11.46 5 232635 14 42388681
Abscess bacterial 14.48 11.46 11 232629 211 42388484
Drug dose omission by device 14.46 11.46 7 232633 5879 42382816
Myelosuppression 14.44 11.46 146 232494 40315 42348380
Osteitis 14.43 11.46 30 232610 1674 42387021
Clostridium difficile infection 14.41 11.46 188 232452 22471 42366224
Erythrophagocytosis 14.40 11.46 6 232634 32 42388663
Skin abrasion 14.40 11.46 14 232626 8161 42380534
Enterobacter bacteraemia 14.39 11.46 17 232623 578 42388117
Vascular compression 14.38 11.46 14 232626 380 42388315
Myocarditis toxoplasmal 14.33 11.46 7 232633 57 42388638
Bronchopneumopathy 14.30 11.46 17 232623 582 42388113
Oropharyngeal squamous cell carcinoma 14.30 11.46 12 232628 267 42388428
Poikiloderma 14.29 11.46 13 232627 323 42388372
Colitis 14.28 11.46 344 232296 46228 42342467
Encephalitis fungal 14.26 11.46 11 232629 216 42388479
Adhesiolysis 14.23 11.46 5 232635 15 42388680
Spontaneous intrahepatic portosystemic venous shunt 14.23 11.46 5 232635 15 42388680
Taste disorder 14.23 11.46 21 232619 10186 42378509
Brain oedema 14.22 11.46 144 232496 16183 42372512
Purpura 14.19 11.46 27 232613 11852 42376843
Encephalomyelitis 14.14 11.46 9 232631 128 42388567
Retroperitonitis 14.11 11.46 4 232636 4 42388691
Sinus perforation 14.11 11.46 4 232636 4 42388691
Oesophageal compression 14.11 11.46 4 232636 4 42388691
Insulin resistant diabetes 14.11 11.46 4 232636 4 42388691
Respiratory distress 14.09 11.46 313 232327 41507 42347188
Infertility 14.05 11.46 11 232629 221 42388474
Aortic valve thickening 14.03 11.46 7 232633 60 42388635
Septic pulmonary embolism 13.96 11.46 9 232631 131 42388564
Infusion site pain 13.90 11.46 6 232634 5389 42383306
Psychomotor hyperactivity 13.90 11.46 24 232616 10934 42377761
Otitis media 13.88 11.46 48 232592 3635 42385060
Renal artery thrombosis 13.84 11.46 13 232627 337 42388358
Norovirus test positive 13.83 11.46 7 232633 62 42388633
Myopathy 13.78 11.46 125 232515 13636 42375059
Hypotonia 13.78 11.46 19 232621 9480 42379215
Peripheral artery aneurysm 13.75 11.46 16 232624 535 42388160
Urethral polyp 13.74 11.46 7 232633 63 42388632
Cyst 13.69 11.46 6 232634 5340 42383355
Page kidney 13.68 11.46 6 232634 37 42388658
Intra-abdominal haemorrhage 13.61 11.46 41 232599 2887 42385808
Tooth loss 13.61 11.46 3 232637 4151 42384544
Rash morbilliform 13.60 11.46 3 232637 4150 42384545
Intestinal metastasis 13.59 11.46 13 232627 345 42388350
Blood sodium decreased 13.59 11.46 52 232588 18110 42370585
Oropharyngeal discomfort 13.58 11.46 3 232637 4146 42384549
Disseminated Bacillus Calmette-Guerin infection 13.57 11.46 12 232628 287 42388408
Abscess 13.56 11.46 128 232512 14120 42374575
Inhibin B 13.55 11.46 5 232635 18 42388677
Angiosarcoma recurrent 13.55 11.46 5 232635 18 42388677
Hip arthroplasty 13.51 11.46 6 232634 5299 42383396
Glomerular vascular disorder 13.50 11.46 9 232631 139 42388556
Biopsy kidney 13.46 11.46 7 232633 66 42388629
Pulmonary oedema 13.45 11.46 207 232433 53065 42335630
Perineal cyst 13.44 11.46 11 232629 236 42388459
Pulse absent 13.43 11.46 9 232631 6318 42382377
Oral disorder 13.43 11.46 57 232583 4755 42383940
Gastrointestinal ulcer 13.43 11.46 31 232609 1859 42386836
Emotional disorder 13.38 11.46 9 232631 6305 42382390
Peritoneal candidiasis 13.34 11.46 5 232635 19 42388676
Arteriovenous fistula aneurysm 13.34 11.46 5 232635 19 42388676
Splenic peliosis 13.34 11.46 5 232635 19 42388676
Splenic neoplasm malignancy unspecified 13.34 11.46 5 232635 19 42388676
Feeding disorder 13.33 11.46 16 232624 8475 42380220
Pulmonary fibrosis 13.31 11.46 88 232552 26593 42362102
Staphylococcal skin infection 13.31 11.46 22 232618 1029 42387666
Unmasking of previously unidentified disease 13.30 11.46 24 232616 1205 42387490
Urinary tract infection pseudomonal 13.30 11.46 25 232615 1296 42387399
Dysbiosis 13.29 11.46 19 232621 782 42387913
High-grade B-cell lymphoma 13.29 11.46 10 232630 189 42388506
Poor venous access 13.26 11.46 12 232628 7240 42381455
Solid organ transplant rejection 13.23 11.46 4 232636 6 42388689
Anal fissure 13.23 11.46 6 232634 5233 42383462
Subcutaneous emphysema 13.22 11.46 29 232611 1680 42387015
Sweat gland tumour 13.22 11.46 14 232626 421 42388274
Pulmonary arterial hypertension 13.21 11.46 22 232618 10165 42378530
Reactive gastropathy 13.20 11.46 16 232624 559 42388136
Disability 13.20 11.46 8 232632 5925 42382770
Heparin-induced thrombocytopenia 13.20 11.46 10 232630 6587 42382108
Tongue ulceration 13.16 11.46 26 232614 1399 42387296
Colitis herpes 13.14 11.46 5 232635 20 42388675
Coronary artery occlusion 13.13 11.46 25 232615 10972 42377723
Renal haemorrhage 13.13 11.46 28 232612 1591 42387104
Lung adenocarcinoma stage IV 13.13 11.46 9 232631 146 42388549
Alcohol abuse 13.11 11.46 3 232637 4046 42384649
Periorbital cellulitis 13.11 11.46 13 232627 361 42388334
Hypokinesia 13.10 11.46 21 232619 9850 42378845
Muscle tightness 13.05 11.46 7 232633 5546 42383149
Papilloma 13.05 11.46 13 232627 363 42388332
Tuberculous pleurisy 13.03 11.46 14 232626 428 42388267
Blood pressure ambulatory increased 13.03 11.46 7 232633 71 42388624
Cytomegalovirus duodenitis 13.03 11.46 7 232633 71 42388624
Perforation bile duct 13.03 11.46 7 232633 71 42388624
Intentional dose omission 13.01 11.46 18 232622 8968 42379727
Wound evisceration 12.99 11.46 8 232632 107 42388588
Morphoea 12.98 11.46 11 232629 248 42388447
Iron overload 12.97 11.46 27 232613 1508 42387187
Anosmia 12.96 11.46 6 232634 5170 42383525
Lacrimation increased 12.96 11.46 28 232612 11730 42376965
Protein-losing gastroenteropathy 12.95 11.46 14 232626 431 42388264
B-lymphocyte abnormalities 12.95 11.46 5 232635 21 42388674
Tooth hypoplasia 12.95 11.46 11 232629 249 42388446
Precursor T-lymphoblastic lymphoma/leukaemia 12.93 11.46 6 232634 43 42388652
Tracheobronchitis 12.87 11.46 25 232615 1328 42387367
Haemarthrosis 12.87 11.46 3 232637 3995 42384700
Hypochromic anaemia 12.87 11.46 22 232618 1058 42387637
Malacoplakia vesicae 12.86 11.46 4 232636 7 42388688
Vestibular nystagmus 12.86 11.46 4 232636 7 42388688
Carotid artery perforation 12.86 11.46 4 232636 7 42388688
Endocarditis viral 12.86 11.46 4 232636 7 42388688
St. Louis encephalitis 12.86 11.46 4 232636 7 42388688
Anal ulcer 12.84 11.46 23 232617 1148 42387547
Cold type haemolytic anaemia 12.81 11.46 10 232630 200 42388495
Dysplasia 12.78 11.46 22 232618 1064 42387631
Meningitis enterococcal 12.77 11.46 9 232631 153 42388542
Dermatitis exfoliative generalised 12.75 11.46 8 232632 5816 42382879
Renal tubular dysfunction 12.72 11.46 14 232626 440 42388255
MAGIC syndrome 12.70 11.46 6 232634 45 42388650
Actinomyces test positive 12.65 11.46 3 232637 0 42388695
Optic pathway injury 12.65 11.46 3 232637 0 42388695
Aeromonas test positive 12.65 11.46 3 232637 0 42388695
Small intestine transplant 12.65 11.46 3 232637 0 42388695
Exserohilum infection 12.65 11.46 3 232637 0 42388695
Aprosody 12.65 11.46 3 232637 0 42388695
Retroperitoneal effusion 12.65 11.46 3 232637 0 42388695
Conjunctival neoplasm 12.65 11.46 3 232637 0 42388695
Pulmonary sensitisation 12.65 11.46 3 232637 0 42388695
Organ transplant 12.65 11.46 3 232637 0 42388695
Leukoencephalomyelitis 12.65 11.46 3 232637 0 42388695
Bile duct cancer recurrent 12.65 11.46 3 232637 0 42388695
Libido decreased 12.62 11.46 6 232634 5092 42383603
Pneumonia escherichia 12.62 11.46 17 232623 661 42388034
Bladder spasm 12.62 11.46 23 232617 1164 42387531
Granulomatous rosacea 12.62 11.46 9 232631 156 42388539
Adult failure to thrive 12.62 11.46 7 232633 76 42388619
Back injury 12.61 11.46 4 232636 4344 42384351
Cervical spinal cord paralysis 12.59 11.46 5 232635 23 42388672
Corneal graft rejection 12.59 11.46 6 232634 46 42388649
Bladder transitional cell carcinoma stage III 12.59 11.46 6 232634 46 42388649
Pneumonia toxoplasmal 12.59 11.46 6 232634 46 42388649
Blood beta-D-glucan increased 12.58 11.46 15 232625 515 42388180
Wound infection bacterial 12.56 11.46 12 232628 318 42388377
Narrow anterior chamber angle 12.55 11.46 8 232632 114 42388581
Meningitis streptococcal 12.54 11.46 7 232633 77 42388618
Intervertebral disc degeneration 12.53 11.46 13 232627 7354 42381341
Seborrhoeic keratosis 12.53 11.46 28 232612 1643 42387052
Varicella keratitis 12.51 11.46 4 232636 8 42388687
Adenovirus reactivation 12.51 11.46 13 232627 382 42388313
Burns second degree 12.51 11.46 9 232631 6087 42382608
Heart transplant 12.49 11.46 21 232619 996 42387699
Plasma cell myeloma recurrent 12.48 11.46 8 232632 5749 42382946
Parainfluenzae virus infection 12.47 11.46 46 232594 3597 42385098
Arterial disorder 12.45 11.46 24 232616 1268 42387427
Perihepatic abscess 12.44 11.46 8 232632 116 42388579
Post procedural complication 12.43 11.46 114 232526 12476 42376219
Panophthalmitis 12.42 11.46 5 232635 24 42388671
VIth nerve paralysis 12.42 11.46 20 232620 915 42387780
Anal incontinence 12.41 11.46 20 232620 9361 42379334
Irritable bowel syndrome 12.40 11.46 5 232635 4676 42384019
Drooling 12.39 11.46 4 232636 4295 42384400
Wound infection staphylococcal 12.37 11.46 26 232614 1462 42387233
Hepatorenal syndrome 12.37 11.46 39 232601 2815 42385880
Decubitus ulcer 12.35 11.46 24 232616 10453 42378242
Cardiac septal hypertrophy 12.35 11.46 13 232627 388 42388307
Colorectal adenocarcinoma 12.35 11.46 12 232628 325 42388370
Lymph gland infection 12.32 11.46 10 232630 212 42388483
Small intestine adenocarcinoma 12.28 11.46 10 232630 213 42388482
Cardiac index increased 12.26 11.46 5 232635 25 42388670
Drug trough level 12.20 11.46 4 232636 9 42388686
Tropical spastic paresis 12.20 11.46 4 232636 9 42388686
Varicella zoster sepsis 12.20 11.46 4 232636 9 42388686
Depressive symptom 12.19 11.46 3 232637 3850 42384845
Hypocalvaria 12.17 11.46 6 232634 50 42388645
Palatal ulcer 12.17 11.46 6 232634 50 42388645
Tracheitis 12.16 11.46 21 232619 1018 42387677
Dyspnoea at rest 12.16 11.46 4 232636 4245 42384450
Coinfection 12.16 11.46 7 232633 82 42388613
Aphthous ulcer 12.16 11.46 64 232576 5837 42382858
Dyschromatopsia 12.16 11.46 15 232625 534 42388161
Subcutaneous abscess 12.15 11.46 53 232587 4475 42384220
Hirsutism 12.11 11.46 11 232629 273 42388422
Acquired macroglossia 12.10 11.46 5 232635 26 42388669
Primary syphilis 12.10 11.46 5 232635 26 42388669
Hypertrophic osteoarthropathy 12.09 11.46 7 232633 83 42388612
Muscle necrosis 12.08 11.46 21 232619 1024 42387671
Escherichia test positive 12.07 11.46 24 232616 1297 42387398
Peripheral vascular disorder 12.07 11.46 7 232633 5310 42383385
Milk-alkali syndrome 12.07 11.46 17 232623 690 42388005
Diabetic nephropathy 12.05 11.46 34 232606 2307 42386388
Acid fast bacilli infection 12.03 11.46 8 232632 123 42388572
Bone disorder 12.03 11.46 11 232629 6602 42382093
Intestinal adenocarcinoma 12.02 11.46 7 232633 84 42388611
Metastases to abdominal cavity 11.97 11.46 11 232629 277 42388418
Megakaryocytes abnormal 11.97 11.46 6 232634 52 42388643
Leiomyosarcoma 11.96 11.46 9 232631 170 42388525
Oesophageal infection 11.93 11.46 12 232628 339 42388356
International normalised ratio decreased 11.92 11.46 5 232635 4567 42384128
Haemorrhagic pneumonia 11.92 11.46 9 232631 171 42388524
Encephalitis cytomegalovirus 11.92 11.46 23 232617 1216 42387479
Immune-mediated myositis 11.91 11.46 3 232637 3790 42384905
Ureteric fistula 11.91 11.46 4 232636 10 42388685
Tonsillar neoplasm 11.91 11.46 4 232636 10 42388685
Atrial flutter 11.89 11.46 51 232589 17200 42371495
Urethral stenosis 11.82 11.46 20 232620 954 42387741
Refractoriness to platelet transfusion 11.81 11.46 7 232633 87 42388608
Asymptomatic viral hepatitis 11.80 11.46 5 232635 28 42388667
Splenic lesion 11.79 11.46 12 232628 344 42388351
Blood testosterone decreased 11.79 11.46 6 232634 4896 42383799
Ectropion 11.78 11.46 9 232631 174 42388521
Perioral dermatitis 11.78 11.46 10 232630 226 42388469
Rash erythematous 11.78 11.46 115 232525 31976 42356719
Circulatory collapse 11.77 11.46 78 232562 23558 42365137
Molluscum contagiosum 11.76 11.46 12 232628 345 42388350
Capillary leak syndrome 11.74 11.46 37 232603 2670 42386025
Prescribed underdose 11.74 11.46 24 232616 10258 42378437
Anastomotic haemorrhage 11.71 11.46 10 232630 228 42388467
Cholangiocarcinoma 11.70 11.46 27 232613 1619 42387076
Eosinophilic pneumonia 11.67 11.46 6 232634 4868 42383827
Plasmacytoma 11.65 11.46 51 232589 4313 42384382
Hepatic cancer metastatic 11.64 11.46 18 232622 795 42387900
Tooth infection 11.64 11.46 16 232624 7995 42380700
Ankle fracture 11.64 11.46 6 232634 4860 42383835
Herpes zoster reactivation 11.63 11.46 13 232627 416 42388279
Systemic viral infection 11.60 11.46 8 232632 131 42388564
Enamel anomaly 11.60 11.46 10 232630 231 42388464
Beta haemolytic streptococcal infection 11.60 11.46 19 232621 882 42387813
Feeling jittery 11.60 11.46 5 232635 4493 42384202
Primary hyperaldosteronism 11.57 11.46 9 232631 179 42388516
Geotrichum infection 11.56 11.46 15 232625 562 42388133
Hepatic vein thrombosis 11.54 11.46 7 232633 91 42388604
Optic perineuritis 11.52 11.46 5 232635 30 42388665
Hepatitis B surface antigen positive 11.50 11.46 8 232632 133 42388562
Cord blood transplant therapy 11.50 11.46 6 232634 57 42388638
Serositis 11.50 11.46 11 232629 292 42388403
Madarosis 11.49 11.46 14 232626 492 42388203

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 9216.66 11.03 3383 374899 21184 110189833
Post transplant lymphoproliferative disorder 6467.21 11.03 2314 375968 13299 110197718
Cytomegalovirus infection 6399.98 11.03 3305 374977 51139 110159878
Immunosuppressant drug level increased 4754.83 11.03 1711 376571 10013 110201004
Thrombotic microangiopathy 4511.80 11.03 2135 376147 27014 110184003
Polyomavirus-associated nephropathy 4183.18 11.03 1420 376862 6781 110204236
Kidney transplant rejection 3071.35 11.03 1252 377030 10735 110200282
Cytomegalovirus viraemia 3017.63 11.03 1388 376894 16376 110194641
BK virus infection 2621.28 11.03 1148 377134 11958 110199059
Epstein-Barr virus infection 2475.72 11.03 1232 377050 17506 110193511
Complications of transplanted kidney 2432.09 11.03 927 377355 6515 110204502
Transplant dysfunction 2404.26 11.03 948 377334 7380 110203637
Nocardiosis 2087.16 11.03 831 377451 6655 110204362
Acute graft versus host disease 2024.80 11.03 954 377328 11927 110199090
Drug interaction 2014.30 11.03 4932 373350 495251 109715766
Liver transplant rejection 2008.07 11.03 681 377601 3237 110207780
Aspergillus infection 1977.48 11.03 1180 377102 24436 110186581
Graft versus host disease 1878.22 11.03 1025 377257 17781 110193236
Product use in unapproved indication 1865.46 11.03 4472 373810 442905 109768112
Drug level increased 1804.17 11.03 1414 376868 46305 110164712
COVID-19 1678.57 11.03 3007 375275 242053 109968964
Off label use 1630.62 11.03 9692 368590 1490493 108720524
Bronchopulmonary aspergillosis 1610.63 11.03 1097 377185 28766 110182251
Posterior reversible encephalopathy syndrome 1590.93 11.03 1143 377139 32718 110178299
Renal impairment 1565.01 11.03 2520 375762 185925 110025092
Acute kidney injury 1561.51 11.03 5245 373037 630185 109580832
Cytomegalovirus infection reactivation 1545.15 11.03 894 377388 17439 110193578
Multiple organ dysfunction syndrome 1535.33 11.03 2224 376058 149486 110061531
Fatigue 1494.42 11.03 1188 377094 1214770 108996247
Polyomavirus viraemia 1464.72 11.03 522 377760 2952 110208065
Nephropathy toxic 1386.74 11.03 969 377313 26509 110184508
Mucormycosis 1360.21 11.03 684 377598 9944 110201073
Pneumocystis jirovecii pneumonia 1340.77 11.03 1136 377146 41599 110169418
Chronic graft versus host disease 1336.12 11.03 651 377631 8806 110202211
Parvovirus B19 infection 1333.42 11.03 464 377818 2417 110208600
Adenovirus infection 1318.02 11.03 677 377605 10317 110200700
Pain 1255.82 11.03 868 377414 954087 109256930
Transplant failure 1252.71 11.03 532 377750 5103 110205914
Acute graft versus host disease in skin 1251.93 11.03 649 377633 10091 110200926
Phaeohyphomycosis 1244.69 11.03 388 377894 1326 110209691
Klebsiella infection 1233.58 11.03 799 377483 19210 110191807
Enterococcal infection 1186.61 11.03 785 377497 19581 110191436
Renal transplant failure 1172.82 11.03 414 377868 2266 110208751
Septic shock 1168.58 11.03 2003 376279 155525 110055492
Dizziness 1098.64 11.03 508 377774 697685 109513332
Delayed graft function 1088.15 11.03 444 377838 3813 110207204
Arthralgia 1068.30 11.03 676 377606 778956 109432061
Joint swelling 1048.69 11.03 138 378144 442707 109768310
Escherichia infection 1046.18 11.03 772 377510 23044 110187973
Pseudomonas infection 1045.37 11.03 822 377460 27031 110183986
Chronic allograft nephropathy 1040.48 11.03 357 377925 1769 110209248
Pulmonary nocardiosis 1029.38 11.03 374 377908 2255 110208762
Immunosuppressant drug level decreased 1021.23 11.03 377 377905 2394 110208623
Malacoplakia 991.93 11.03 303 377979 949 110210068
Diffuse large B-cell lymphoma 955.90 11.03 625 377657 15273 110195744
Fall 930.73 11.03 451 377831 603031 109607986
Haemophagocytic lymphohistiocytosis 929.03 11.03 809 377473 30750 110180267
Graft versus host disease in skin 922.67 11.03 485 377797 7769 110203248
Dyspnoea 917.41 11.03 1486 376796 1105386 109105631
Drug hypersensitivity 913.50 11.03 216 378066 453874 109757143
Epstein-Barr viraemia 907.01 11.03 371 377911 3208 110207809
Respiratory failure 900.96 11.03 2158 376124 213174 109997843
Infusion related reaction 889.91 11.03 124 378158 381038 109829979
Leukopenia 863.50 11.03 1702 376580 147089 110063928
Focal segmental glomerulosclerosis 861.01 11.03 373 377909 3772 110207245
Graft versus host disease in gastrointestinal tract 857.36 11.03 475 377807 8493 110202524
Cryptococcosis 856.23 11.03 384 377898 4247 110206770
Nausea 855.76 11.03 1850 376432 1233840 108977177
Brain abscess 855.22 11.03 432 377850 6342 110204675
Arthropathy 829.61 11.03 36 378246 287486 109923531
Synovitis 823.05 11.03 25 378257 274067 109936950
Hypersensitivity 812.84 11.03 192 378090 403806 109807211
Epstein-Barr virus associated lymphoproliferative disorder 808.37 11.03 373 377909 4429 110206588
Trichodysplasia spinulosa 797.44 11.03 246 378036 804 110210213
Acute respiratory distress syndrome 787.89 11.03 941 377341 52257 110158760
Peripheral swelling 766.94 11.03 216 378066 403818 109807199
Strongyloidiasis 752.04 11.03 359 377923 4627 110206390
Cytomegalovirus colitis 747.16 11.03 400 377882 6661 110204356
Human herpesvirus 8 infection 746.87 11.03 270 378012 1601 110209416
Malaise 737.61 11.03 727 377555 671092 109539925
Histoplasmosis disseminated 729.48 11.03 326 377956 3573 110207444
Completed suicide 720.93 11.03 24 378258 242357 109968660
Kidney fibrosis 720.18 11.03 335 377947 4057 110206960
Glossodynia 711.22 11.03 9 378273 221995 109989022
Smooth muscle cell neoplasm 705.37 11.03 241 378041 1176 110209841
Pain in extremity 703.36 11.03 396 377886 486722 109724295
Meningitis cryptococcal 700.40 11.03 337 377945 4425 110206592
Pemphigus 690.50 11.03 8 378274 214562 109996455
Post transplant distal limb syndrome 687.85 11.03 211 378071 673 110210344
Heart transplant rejection 661.19 11.03 252 378030 1769 110209248
Blood creatinine increased 651.84 11.03 1725 376557 181164 110029853
Contraindicated product administered 650.04 11.03 53 378229 248214 109962803
Nasopharyngitis 647.77 11.03 269 378013 394092 109816925
Renal tubular injury 627.04 11.03 274 378008 2834 110208183
Infection reactivation 625.17 11.03 297 377985 3784 110207233
Abdominal discomfort 621.03 11.03 285 377997 393573 109817444
Alternaria infection 618.89 11.03 201 378081 811 110210206
JC virus infection 617.48 11.03 320 377962 4970 110206047
Renal tubular necrosis 617.00 11.03 635 377647 29840 110181177
Swelling 612.09 11.03 218 378064 350823 109860194
Disease recurrence 611.21 11.03 889 377393 59895 110151122
Drug ineffective for unapproved indication 610.56 11.03 1188 377094 101650 110109367
Acute graft versus host disease in intestine 603.85 11.03 322 377960 5317 110205700
Rash 600.82 11.03 1189 377093 819775 109391242
Hepatitis E 600.15 11.03 297 377985 4162 110206855
Varicella zoster virus infection 594.29 11.03 332 377950 6036 110204981
Graft loss 584.36 11.03 206 378076 1122 110209895
Mobility decreased 583.72 11.03 65 378217 237357 109973660
Lung transplant rejection 579.06 11.03 226 378056 1705 110209312
Pneumonia cytomegaloviral 577.64 11.03 336 377946 6618 110204399
Aplasia pure red cell 576.92 11.03 377 377905 9201 110201816
Wheezing 574.83 11.03 92 378190 255138 109955879
Wound 574.31 11.03 65 378217 234372 109976645
Scedosporium infection 572.83 11.03 240 378042 2218 110208799
Blastomycosis 572.66 11.03 195 378087 940 110210077
Chronic graft versus host disease in skin 571.34 11.03 244 378038 2375 110208642
Musculoskeletal stiffness 568.53 11.03 130 378152 279692 109931325
Human polyomavirus infection 565.56 11.03 218 378064 1584 110209433
Neurotoxicity 562.54 11.03 708 377574 41499 110169518
Asthenia 559.13 11.03 936 377346 688063 109522954
Fibromyalgia 551.58 11.03 6 378276 170903 110040114
Duodenal ulcer perforation 545.33 11.03 13 378269 177687 110033330
Pneumatosis intestinalis 543.97 11.03 348 377934 8181 110202836
Sepsis 543.23 11.03 2389 375893 324957 109886060
Candida infection 541.70 11.03 742 377540 47267 110163750
Hepatitis C 535.21 11.03 400 377882 12173 110198844
Venoocclusive liver disease 534.69 11.03 432 377850 14775 110196242
Drug abuse 533.14 11.03 16 378266 177395 110033622
Cystitis haemorrhagic 532.20 11.03 394 377888 11815 110199202
Systemic lupus erythematosus 531.21 11.03 111 378171 254227 109956790
Fungal infection 523.84 11.03 752 377530 50054 110160963
Anxiety 523.61 11.03 263 378019 344815 109866202
Cytomegalovirus test positive 521.84 11.03 316 377966 6720 110204297
West Nile viral infection 513.06 11.03 187 378095 1139 110209878
Helicobacter infection 510.89 11.03 27 378255 181850 110029167
Hypoaesthesia 508.41 11.03 219 378063 314004 109897013
Headache 507.78 11.03 1451 376831 880926 109330091
COVID-19 pneumonia 504.50 11.03 629 377653 36514 110174503
Viraemia 501.50 11.03 256 378026 3846 110207171
Weight increased 498.18 11.03 422 377860 419222 109791795
Constipation 497.58 11.03 304 377978 357482 109853535
Systemic mycosis 494.54 11.03 248 378034 3581 110207436
Cryptosporidiosis infection 490.38 11.03 174 378108 969 110210048
Irritable bowel syndrome 489.17 11.03 16 378266 164199 110046818
Psoriatic arthropathy 488.40 11.03 52 378230 196709 110014308
Epstein-Barr virus infection reactivation 488.07 11.03 251 378031 3833 110207184
Renal tubular atrophy 486.47 11.03 209 378073 2067 110208950
Depression 485.75 11.03 239 378043 317096 109893921
Staphylococcal infection 480.06 11.03 860 377422 69084 110141933
Therapeutic product effect decreased 475.79 11.03 124 378158 244192 109966825
Bacteraemia 475.01 11.03 653 377629 41737 110169280
Toxicity to various agents 474.30 11.03 3038 375244 477517 109733500
Urticaria 473.35 11.03 250 378032 318607 109892410
Proteinuria 472.01 11.03 632 377650 39386 110171631
Dermatitis atopic 466.84 11.03 504 377778 25037 110185980
Pericarditis 463.00 11.03 93 378189 219021 109991996
Muscle spasms 459.38 11.03 188 378094 277969 109933048
Pulmonary mucormycosis 455.45 11.03 196 378086 1947 110209070
Renal graft infection 453.25 11.03 149 378133 630 110210387
Pathogen resistance 445.10 11.03 415 377867 17257 110193760
Haemolytic uraemic syndrome 441.11 11.03 251 378031 4734 110206283
Human herpesvirus 6 infection 438.36 11.03 276 378006 6305 110204712
Asthma 435.19 11.03 156 378126 250135 109960882
Insomnia 434.84 11.03 357 377925 360233 109850784
Herpes simplex 433.75 11.03 389 377893 15375 110195642
Dry mouth 424.27 11.03 84 378198 199864 110011153
Stenotrophomonas infection 423.95 11.03 259 378023 5599 110205418
Squamous cell carcinoma of skin 423.71 11.03 399 377883 16804 110194213
Contusion 422.13 11.03 136 378146 233225 109977792
Back pain 416.37 11.03 393 377889 370603 109840414
Rheumatoid arthritis 407.64 11.03 261 378021 299352 109911665
Sinusitis 407.02 11.03 256 378026 296432 109914585
Pancytopenia 406.36 11.03 1605 376677 208008 110003009
Injury 405.66 11.03 61 378221 177204 110033813
Lower respiratory tract infection 400.29 11.03 165 378117 242941 109968076
Folliculitis 397.01 11.03 52 378230 167601 110043416
Progressive multifocal leukoencephalopathy 395.28 11.03 457 377825 24499 110186518
Hepatic enzyme increased 395.25 11.03 311 377971 320581 109890436
Chest pain 393.49 11.03 424 377858 375951 109835066
Drug resistance 390.50 11.03 696 377586 55678 110155339
Toxoplasmosis 386.88 11.03 199 378083 3040 110207977
Histoplasmosis 386.51 11.03 193 378089 2760 110208257
Blister 384.73 11.03 148 378134 227228 109983789
Atypical haemolytic uraemic syndrome 381.26 11.03 157 378125 1383 110209634
Osteoarthritis 380.66 11.03 80 378202 182543 110028474
Squamous cell carcinoma 376.05 11.03 386 377896 18077 110192940
Paraesthesia 376.01 11.03 241 378041 276280 109934737
Disseminated cryptococcosis 375.58 11.03 183 378099 2474 110208543
Lymphoproliferative disorder 374.53 11.03 259 378023 6959 110204058
Fungal skin infection 373.52 11.03 259 378023 6990 110204027
Vomiting 373.12 11.03 1725 376557 908950 109302067
Blood cholesterol increased 372.94 11.03 87 378195 184698 110026319
Mycobacterial infection 371.06 11.03 215 378067 4202 110206815
Somnolence 369.21 11.03 286 377996 297163 109913854
C-reactive protein abnormal 368.19 11.03 18 378264 129677 110081340
Drug ineffective 365.00 11.03 7251 371031 1513289 108697728
Abdominal pain upper 364.13 11.03 394 377888 348717 109862300
Type 2 diabetes mellitus 360.56 11.03 82 378200 177150 110033867
Ill-defined disorder 358.85 11.03 54 378228 156799 110054218
Alveolar proteinosis 354.68 11.03 149 378133 1387 110209630
Musculoskeletal pain 354.19 11.03 94 378188 182929 110028088
Confusional state 351.53 11.03 668 377614 468012 109743005
Memory impairment 341.90 11.03 123 378159 196821 110014196
Hypogammaglobulinaemia 338.92 11.03 380 377902 19696 110191321
Actinic keratosis 334.48 11.03 239 378043 6774 110204243
Drug intolerance 333.18 11.03 548 377734 405964 109805053
Premature delivery 329.91 11.03 463 377819 30169 110180848
Viral haemorrhagic cystitis 327.55 11.03 181 378101 3218 110207799
Product dose omission issue 326.94 11.03 371 377911 321411 109889606
Bursitis 325.82 11.03 33 378249 129885 110081132
Migraine 323.11 11.03 93 378189 171559 110039458
Syncope 322.98 11.03 144 378138 202392 110008625
Ovarian cyst 320.16 11.03 311 377971 13619 110197398
Lymphocele 320.15 11.03 147 378135 1724 110209293
Transplantation associated food allergy 317.02 11.03 78 378204 67 110210950
General physical health deterioration 316.41 11.03 609 377673 424686 109786331
Stomatitis 315.34 11.03 276 378006 269966 109941051
Pneumonia cryptococcal 314.71 11.03 160 378122 2382 110208635
Diabetes mellitus 312.72 11.03 896 377386 98485 110112532
Renal failure 310.66 11.03 1565 376717 225009 109986008
Intentional overdose 309.18 11.03 43 378239 132458 110078559
Pneumonia fungal 306.92 11.03 312 377970 14442 110196575
Enterobacter infection 300.30 11.03 208 378074 5603 110205414
Lip dry 297.16 11.03 10 378272 100073 110110944
Glomerulonephritis 296.71 11.03 191 378091 4539 110206478
Rhodococcus infection 295.28 11.03 97 378185 409 110210608
Decreased appetite 293.70 11.03 755 377527 475091 109735926
New onset diabetes after transplantation 291.90 11.03 92 378190 329 110210688
Complications of transplanted lung 291.05 11.03 104 378178 593 110210424
Organising pneumonia 288.67 11.03 297 377985 13946 110197071
Vaccination failure 287.92 11.03 150 378132 2356 110208661
Pyelonephritis 285.93 11.03 391 377891 24859 110186158
Immune reconstitution inflammatory syndrome 285.74 11.03 314 377968 15912 110195105
Chronic obstructive pulmonary disease 283.68 11.03 24 378258 109134 110101883
Chronic kidney disease 281.15 11.03 729 377553 75562 110135455
Hyperhidrosis 280.56 11.03 145 378137 187153 110023864
Disseminated mucormycosis 279.90 11.03 139 378143 1963 110209054
Acute graft versus host disease in liver 276.19 11.03 143 378139 2216 110208801
Gait inability 275.58 11.03 64 378218 136312 110074705
Road traffic accident 275.33 11.03 25 378257 107373 110103644
Feeling abnormal 275.02 11.03 137 378145 180574 110030443
Drug level fluctuating 273.12 11.03 109 378173 878 110210139
Ureaplasma infection 272.50 11.03 124 378158 1422 110209595
Discomfort 272.06 11.03 202 378080 214505 109996512
Joint range of motion decreased 271.76 11.03 45 378237 121787 110089230
Obesity 271.14 11.03 34 378248 113317 110097700
Dermatophytosis 270.67 11.03 94 378188 486 110210531
Renal tubular acidosis 270.39 11.03 180 378102 4535 110206482
Malignant neoplasm progression 269.22 11.03 130 378152 174437 110036580
Dyspepsia 267.06 11.03 161 378121 190804 110020213
Cat scratch disease 265.85 11.03 96 378186 567 110210450
Pneumonia bacterial 263.80 11.03 384 377898 25877 110185140
Drug level decreased 262.96 11.03 321 377961 18227 110192790
Drug level above therapeutic 261.24 11.03 256 378026 11332 110199685
Tubulointerstitial nephritis 260.82 11.03 575 377707 53709 110157308
Hydronephrosis 258.55 11.03 336 377946 20329 110190688
Sleep disorder 256.74 11.03 183 378099 198461 110012556
Norovirus infection 256.24 11.03 136 378146 2223 110208794
Impaired healing 255.86 11.03 180 378102 196537 110014480
Pruritus 255.64 11.03 1072 377210 580488 109630529
Arthritis 255.10 11.03 127 378155 167459 110043558
IgA nephropathy 254.80 11.03 150 378132 3023 110207994
Mycobacterium abscessus infection 254.74 11.03 122 378160 1584 110209433
Gastrooesophageal reflux disease 252.70 11.03 151 378131 179825 110031192
Mycoplasma infection 252.33 11.03 114 378168 1284 110209733
Pancreas transplant rejection 251.72 11.03 80 378202 296 110210721
Gait disturbance 250.03 11.03 352 377930 277856 109933161
Disseminated tuberculosis 249.17 11.03 177 378105 4969 110206048
Chest discomfort 248.14 11.03 143 378139 173705 110037312
Gastroenteritis norovirus 246.94 11.03 154 378128 3457 110207560
Complications of transplanted liver 246.75 11.03 85 378197 427 110210590
Hypotension 245.76 11.03 941 377341 522908 109688109
Pneumonia pseudomonal 245.65 11.03 205 378077 7341 110203676
Grip strength decreased 245.41 11.03 6 378276 80168 110130849
Encephalopathy 244.62 11.03 720 377562 80335 110130682
End stage renal disease 243.88 11.03 333 377949 21140 110189877
Pneumocystis jirovecii infection 242.79 11.03 164 378118 4236 110206781
Papilloma viral infection 240.00 11.03 126 378156 2012 110209005
Encephalitis viral 238.45 11.03 141 378141 2866 110208151
Blood pressure increased 236.09 11.03 323 377959 258050 109952967
Graft versus host disease in lung 233.16 11.03 105 378177 1173 110209844
Cytomegalovirus chorioretinitis 232.78 11.03 194 378088 6934 110204083
Malacoplakia gastrointestinal 232.40 11.03 69 378213 190 110210827
Angiosarcoma 230.45 11.03 83 378199 486 110210531
Systemic candida 227.94 11.03 222 378060 9752 110201265
Cerebral toxoplasmosis 227.58 11.03 139 378143 3003 110208014
Human herpesvirus 6 encephalitis 227.49 11.03 98 378184 976 110210041
Adverse event 226.02 11.03 48 378234 108761 110102256
Graft complication 225.77 11.03 99 378183 1033 110209984
Atypical mycobacterial infection 224.88 11.03 131 378151 2587 110208430
Cytomegalovirus enteritis 223.87 11.03 97 378185 981 110210036
Acute myeloid leukaemia recurrent 222.09 11.03 165 378117 4974 110206043
Night sweats 221.99 11.03 90 378192 133893 110077124
Renal transplant 221.20 11.03 138 378144 3100 110207917
Trichophytosis 220.32 11.03 77 378205 407 110210610
Lymphopenia 220.19 11.03 449 377833 39721 110171296
Osmotic demyelination syndrome 218.63 11.03 117 378165 1946 110209071
Donor specific antibody present 217.63 11.03 73 378209 333 110210684
Epidermodysplasia verruciformis 217.20 11.03 75 378207 380 110210637
Peripheral venous disease 217.19 11.03 19 378263 84098 110126919
Anogenital warts 215.77 11.03 96 378186 1040 110209977
Ureteric stenosis 213.82 11.03 106 378176 1491 110209526
Acinetobacter infection 213.62 11.03 140 378142 3433 110207584
Neck pain 213.49 11.03 77 378205 123053 110087964
Complications of transplant surgery 211.99 11.03 85 378197 694 110210323
Nephrotic syndrome 211.88 11.03 249 378033 13582 110197435
Rectal haemorrhage 209.37 11.03 74 378208 119759 110091258
Cerebral aspergillosis 206.62 11.03 117 378165 2185 110208832
Obliterative bronchiolitis 205.98 11.03 139 378143 3584 110207433
Myocardial infarction 205.50 11.03 212 378070 191871 110019146
Palpitations 205.30 11.03 147 378135 159065 110051952
Infection in an immunocompromised host 203.41 11.03 109 378173 1818 110209199
Encephalitis 200.26 11.03 283 377999 18556 110192461
Hepatic artery thrombosis 199.65 11.03 68 378214 328 110210689
Therapeutic product effect incomplete 199.24 11.03 285 377997 223520 109987497
Pneumonia klebsiella 199.15 11.03 172 378110 6460 110204557
Alopecia 198.86 11.03 614 377668 364139 109846878
Gingival hypertrophy 198.32 11.03 144 378138 4187 110206830
Sciatica 197.67 11.03 38 378244 92361 110118656
Disseminated blastomycosis 197.38 11.03 71 378211 414 110210603
Mycobacterium avium complex infection 196.18 11.03 162 378120 5715 110205302
Bacillary angiomatosis 195.20 11.03 66 378216 310 110210707
Muscular weakness 194.20 11.03 345 377937 248123 109962894
Prescribed overdose 193.88 11.03 33 378249 87548 110123469
Endophthalmitis 192.32 11.03 185 378097 8002 110203015
Heart rate decreased 188.09 11.03 29 378253 82727 110128290
Human ehrlichiosis 187.62 11.03 76 378206 639 110210378
Visceral leishmaniasis 187.25 11.03 100 378182 1656 110209361
Deep vein thrombosis postoperative 187.22 11.03 3 378279 59288 110151729
Disseminated intravascular coagulation 186.78 11.03 427 377855 40859 110170158
Cytomegalovirus gastrointestinal infection 186.70 11.03 76 378206 648 110210369
Glomerulosclerosis 186.67 11.03 90 378192 1187 110209830
Enterocolitis viral 185.33 11.03 80 378202 801 110210216
Knee arthroplasty 184.37 11.03 9 378273 64939 110146078
Balance disorder 184.01 11.03 84 378198 116476 110094541
Microsporidia infection 182.31 11.03 92 378190 1347 110209670
Infective aneurysm 182.06 11.03 93 378189 1399 110209618
Red blood cell sedimentation rate increased 181.28 11.03 26 378256 78276 110132741
Complications of transplanted heart 180.52 11.03 66 378216 406 110210611
Suicide attempt 180.37 11.03 64 378218 103330 110107687
Cytomegalovirus oesophagitis 179.86 11.03 81 378201 905 110210112
Glomerulonephritis membranoproliferative 178.21 11.03 77 378205 773 110210244
Emphysematous pyelonephritis 178.10 11.03 69 378213 509 110210508
Hypertrophic cardiomyopathy 177.17 11.03 119 378163 3044 110207973
Shock haemorrhagic 176.72 11.03 327 377955 26920 110184097
Neutrophil Pelger-Huet anomaly present 176.27 11.03 62 378220 335 110210682
Angiosarcoma metastatic 175.19 11.03 52 378230 143 110210874
Mycobacterium haemophilum infection 173.59 11.03 72 378210 647 110210370
Renal artery stenosis 173.16 11.03 125 378157 3601 110207416
Locked-in syndrome 173.00 11.03 78 378204 874 110210143
Oedema peripheral 171.59 11.03 564 377718 328096 109882921
Liver injury 171.32 11.03 157 378125 150256 110060761
Flushing 170.84 11.03 72 378210 104664 110106353
Escherichia urinary tract infection 170.63 11.03 242 378040 15920 110195097
Lower limb fracture 169.89 11.03 27 378255 75321 110135696
Cytomegalovirus gastritis 169.85 11.03 70 378212 618 110210399
Oxygen saturation decreased 169.34 11.03 172 378110 156810 110054207
Adenoviral haemorrhagic cystitis 169.26 11.03 70 378212 624 110210393
Epstein-Barr virus test positive 168.65 11.03 85 378197 1241 110209776
Autoimmune haemolytic anaemia 168.16 11.03 194 378088 10373 110200644
Injection site reaction 168.05 11.03 48 378234 89022 110121995
Penicillium infection 166.72 11.03 68 378214 583 110210434
Fusarium infection 166.71 11.03 109 378173 2662 110208355
Central nervous system infection 166.26 11.03 92 378190 1640 110209377
Chronic graft versus host disease in liver 165.83 11.03 75 378207 847 110210170
Bacterial sepsis 165.22 11.03 191 378091 10235 110200782
Nail disorder 164.54 11.03 8 378274 57927 110153090
Microangiopathic haemolytic anaemia 164.34 11.03 95 378187 1848 110209169
Heart rate increased 163.98 11.03 150 378132 143684 110067333
Liver abscess 163.42 11.03 165 378117 7574 110203443
Loss of consciousness 163.13 11.03 262 378020 196044 110014973
Injection site pain 162.92 11.03 222 378060 177700 110033317
Suicidal ideation 162.41 11.03 59 378223 93878 110117139
Pneumomediastinum 162.25 11.03 136 378146 4900 110206117
Biliary anastomosis complication 161.19 11.03 48 378234 134 110210883
Mycetoma mycotic 160.55 11.03 59 378223 369 110210648
Bacterial infection 160.53 11.03 431 377851 45605 110165412
Pre-eclampsia 160.36 11.03 172 378110 8478 110202539
Cytomegalovirus enterocolitis 160.34 11.03 99 378183 2182 110208835
Engraftment syndrome 159.53 11.03 93 378189 1839 110209178
Acanthamoeba infection 159.29 11.03 65 378217 558 110210459
Necrotising oesophagitis 159.13 11.03 87 378195 1513 110209504
Drug reaction with eosinophilia and systemic symptoms 159.09 11.03 42 378240 82053 110128964
Bradycardia 158.16 11.03 179 378103 155338 110055679
Hypokalaemia 157.81 11.03 237 378045 182211 110028806
Inflammation 157.68 11.03 261 378021 192977 110018040
Monkeypox 157.06 11.03 56 378226 317 110210700
Corynebacterium infection 156.55 11.03 93 378189 1907 110209110
Opportunistic infection 155.90 11.03 115 378167 3428 110207589
Feeling hot 154.53 11.03 59 378223 91047 110119970
Hip arthroplasty 154.47 11.03 9 378273 55804 110155213
Blepharospasm 154.43 11.03 8 378274 54843 110156174
Cerebral fungal infection 153.94 11.03 66 378216 649 110210368
Ascites 153.34 11.03 677 377605 92131 110118886
Graft versus host disease in liver 153.29 11.03 99 378183 2366 110208651
Infectious pleural effusion 153.29 11.03 130 378152 4761 110206256
Acne 153.10 11.03 348 377934 33172 110177845
Central nervous system lymphoma 152.72 11.03 107 378175 2937 110208080
Autoimmune disorder 150.99 11.03 22 378260 65461 110145556
Transitional cell carcinoma 150.95 11.03 108 378174 3067 110207950
Oesophageal ulcer 150.53 11.03 160 378122 7804 110203213
Hypercholesterolaemia 150.49 11.03 61 378221 90776 110120241
Nephropathy 150.15 11.03 207 378075 13260 110197757
Hepatic failure 150.10 11.03 547 377735 68192 110142825
Passenger lymphocyte syndrome 149.65 11.03 46 378236 148 110210869
Escherichia bacteraemia 149.13 11.03 179 378103 9985 110201032
Polyomavirus test positive 148.55 11.03 50 378232 231 110210786
Pneumoperitoneum 148.20 11.03 117 378165 3867 110207150
Hyperkalaemia 147.65 11.03 881 377401 134915 110076102
Vascular pseudoaneurysm ruptured 146.95 11.03 60 378222 516 110210501
Drug effective for unapproved indication 146.43 11.03 210 378072 13957 110197060
Multiple sclerosis relapse 145.76 11.03 6 378276 50234 110160783
Cholangitis 145.73 11.03 226 378056 16109 110194908
Stress 145.60 11.03 90 378192 105258 110105759
Enterovirus infection 145.14 11.03 100 378182 2670 110208347
C-reactive protein increased 145.12 11.03 332 377950 217587 109993430
Pseudoaneurysm infection 144.78 11.03 46 378236 170 110210847
American trypanosomiasis 144.72 11.03 61 378221 573 110210444
Cough 144.34 11.03 955 377327 460686 109750331
Demodicidosis 142.91 11.03 47 378235 199 110210818
Onychomadesis 141.37 11.03 3 378279 45660 110165357
Herpes simplex hepatitis 141.33 11.03 64 378218 725 110210292
Post procedural bile leak 141.32 11.03 54 378228 382 110210635
Liver transplant failure 140.85 11.03 42 378240 118 110210899
Oliguria 140.44 11.03 239 378043 18418 110192599
Medication error 140.18 11.03 94 378188 105272 110105745
Oedema 139.74 11.03 320 377962 209656 110001361
Disseminated varicella zoster virus infection 139.56 11.03 74 378208 1207 110209810
Osteomyelitis fungal 139.05 11.03 53 378229 372 110210645
Hepatocellular carcinoma 138.45 11.03 170 378112 9710 110201307
Skin papilloma 138.31 11.03 143 378139 6753 110204264
Sedation 138.20 11.03 34 378248 69649 110141368
Guillain-Barre syndrome 138.02 11.03 177 378105 10567 110200450
Cystitis viral 138 11.03 77 378205 1396 110209621
Fungal endocarditis 137.79 11.03 64 378218 772 110210245
Amnesia 137.61 11.03 96 378186 105312 110105705
Prophylaxis against transplant rejection 137.41 11.03 38 378244 73 110210944
Back injury 136.39 11.03 6 378276 47393 110163624
Product quality issue 136.29 11.03 47 378235 77252 110133765
Epistaxis 135.93 11.03 147 378135 130225 110080792
Periostitis 135.63 11.03 63 378219 760 110210257
Haemolytic anaemia 135.59 11.03 251 378031 20669 110190348
Cerebrovascular accident 135.15 11.03 259 378023 181025 110029992
Inappropriate schedule of product administration 134.98 11.03 311 377971 203326 110007691
Dislocation of vertebra 134.85 11.03 3 378279 43718 110167299
Pyelonephritis acute 134.72 11.03 144 378138 7069 110203948
Loss of personal independence in daily activities 134.52 11.03 190 378092 149830 110061187
Pleural effusion 134.24 11.03 1054 377228 176655 110034362
Epstein-Barr virus associated lymphoma 134.24 11.03 79 378203 1591 110209426
Injection site erythema 133.59 11.03 78 378204 94098 110116919
Cutaneous malacoplakia 132.44 11.03 41 378241 136 110210881
Gastrointestinal mucormycosis 132.40 11.03 60 378222 681 110210336
Adenoviral hepatitis 132.03 11.03 66 378216 946 110210071
Coronavirus infection 131.76 11.03 163 378119 9382 110201635
Klebsiella bacteraemia 131.67 11.03 119 378163 4750 110206267
Chronic graft versus host disease oral 131.63 11.03 53 378229 438 110210579
Abdominal distension 131.56 11.03 249 378033 174854 110036163
Humoral immune defect 131.47 11.03 60 378222 693 110210324
Clostridium difficile colitis 131.22 11.03 388 377894 43390 110167627
Weight decreased 130.87 11.03 1000 377282 467057 109743960
Gastroenteritis sapovirus 130.20 11.03 43 378239 185 110210832
Reversible cerebral vasoconstriction syndrome 130.01 11.03 117 378165 4644 110206373
Urinary tract infection bacterial 129.88 11.03 149 378133 7918 110203099
Joint stiffness 129.16 11.03 35 378247 67208 110143809
Tremor 129.12 11.03 1155 377127 201077 110009940
Wrong technique in product usage process 128.73 11.03 69 378213 87279 110123738
Enterococcal bacteraemia 128.52 11.03 113 378169 4348 110206669
Cryptococcal cutaneous infection 128.34 11.03 46 378236 265 110210752
Foot deformity 127.78 11.03 10 378272 48470 110162547
Neutrophil count decreased 127.62 11.03 135 378147 120806 110090211
White blood cell count decreased 127.18 11.03 383 377899 229007 109982010
Cardiac failure congestive 126.89 11.03 200 378082 150800 110060217
Peritonitis 126.76 11.03 318 377964 32289 110178728
Chronic myeloid leukaemia 126.65 11.03 110 378172 4163 110206854
Frequent bowel movements 126.57 11.03 43 378239 71347 110139670
Kaposi's sarcoma 125.93 11.03 57 378225 645 110210372
Staphylococcal bacteraemia 125.91 11.03 214 378068 16474 110194543
Disseminated mycobacterium avium complex infection 125.49 11.03 52 378230 466 110210551
Anuria 125.11 11.03 265 378017 24076 110186941
Chronic graft versus host disease in eye 124.82 11.03 49 378233 376 110210641
Full blood count abnormal 124.33 11.03 21 378261 56031 110154986
Optic neuropathy 124.31 11.03 113 378169 4545 110206472
Underdose 124.13 11.03 32 378250 63522 110147495
Oesophageal candidiasis 123.68 11.03 174 378108 11360 110199657
Bile duct stenosis 122.59 11.03 89 378193 2587 110208430
Steroid diabetes 122.05 11.03 118 378164 5136 110205881
Taste disorder 121.95 11.03 36 378246 65351 110145666
Liver transplant 121.83 11.03 111 378171 4478 110206539
Haemodialysis 121.69 11.03 218 378064 17501 110193516
Hepatic fibrosis 121.55 11.03 144 378138 7922 110203095
Central nervous system viral infection 121.45 11.03 45 378237 289 110210728
Intestine transplant rejection 121.02 11.03 35 378247 85 110210932
Lung disorder 120.92 11.03 273 378009 179774 110031243
BK polyomavirus test positive 120.71 11.03 44 378238 268 110210749
Oesophageal stenosis 119.98 11.03 116 378166 5049 110205968
Hypoglycaemia 119.84 11.03 132 378150 115972 110095045
Mediastinitis 119.51 11.03 69 378213 1339 110209678
Meningoencephalitis herpetic 119.50 11.03 84 378198 2318 110208699
Disseminated aspergillosis 119.38 11.03 85 378197 2395 110208622
Idiopathic pneumonia syndrome 119.13 11.03 59 378223 828 110210189
Bronchitis 119.12 11.03 222 378060 156810 110054207
Inflammatory bowel disease 118.81 11.03 135 378147 7099 110203918
Graft thrombosis 118.77 11.03 50 378232 468 110210549
Bone erosion 118.29 11.03 11 378271 46360 110164657
Adverse drug reaction 118.05 11.03 112 378170 105447 110105570
Intentional product misuse 117.50 11.03 170 378112 132734 110078283
Pulmonary alveolar haemorrhage 117.33 11.03 231 378051 19919 110191098
Chromoblastomycosis 117.25 11.03 37 378245 133 110210884
Gastroenteritis cryptosporidial 117.09 11.03 45 378237 324 110210693
Vascular hyalinosis 116.61 11.03 37 378245 136 110210881
Central nervous system fungal infection 116.42 11.03 52 378230 569 110210448
Necrosis 116.32 11.03 168 378114 11238 110199779
X-ray abnormal 116.09 11.03 3 378279 38114 110172903
Neuroendocrine carcinoma of the skin 115.76 11.03 73 378209 1672 110209345
Pulmonary fibrosis 115.61 11.03 107 378175 101935 110109082
Philadelphia positive chronic myeloid leukaemia 115.34 11.03 38 378244 162 110210855
Dysphonia 114.83 11.03 58 378224 75871 110135146
Chronic hepatitis 114.73 11.03 73 378209 1699 110209318
Hyperammonaemia 114.23 11.03 184 378098 13548 110197469
Perinephric abscess 114.15 11.03 46 378236 381 110210636
Lung transplant 114.00 11.03 114 378168 5172 110205845
Nasal congestion 113.80 11.03 101 378181 98181 110112836
Glomerulonephritis membranous 113.73 11.03 76 378206 1927 110209090
Myalgia 113.69 11.03 385 377897 221996 109989021
Psoriasis 113.34 11.03 190 378092 139803 110071214
Encapsulating peritoneal sclerosis 113.17 11.03 57 378225 831 110210186
Metastatic squamous cell carcinoma 113.03 11.03 54 378228 697 110210320
Superinfection bacterial 112.61 11.03 81 378201 2320 110208697
Blood pressure systolic increased 111.80 11.03 73 378209 82918 110128099
Necrotising retinitis 111.50 11.03 69 378213 1527 110209490
Chronic graft versus host disease in intestine 111.17 11.03 52 378230 638 110210379
Bacterial pyelonephritis 111.17 11.03 55 378227 770 110210247
Hepatitis B 110.57 11.03 150 378132 9462 110201555
Disseminated cytomegaloviral infection 109.52 11.03 50 378232 578 110210439
Cutaneous nocardiosis 108.90 11.03 41 378241 277 110210740
Venoocclusive disease 108.55 11.03 121 378161 6229 110204788
Trichosporon infection 108.46 11.03 63 378219 1237 110209780
Laryngitis 108.35 11.03 10 378272 42401 110168616
Ileal ulcer 108.15 11.03 71 378211 1746 110209271
Biliary tract disorder 107.83 11.03 71 378211 1755 110209262
Rhinovirus infection 107.83 11.03 165 378117 11624 110199393
Photodermatosis 107.61 11.03 59 378223 1032 110209985
Kaposi sarcoma inflammatory cytokine syndrome 107.22 11.03 35 378247 144 110210873
Mycobacterium fortuitum infection 107.14 11.03 46 378236 454 110210563
Hot flush 106.72 11.03 46 378236 65990 110145027
Disseminated toxoplasmosis 105.90 11.03 45 378237 432 110210585
Swollen tongue 105.90 11.03 37 378245 60325 110150692
Large intestinal ulcer 105.82 11.03 114 378168 5647 110205370
Citrobacter infection 105.74 11.03 63 378219 1299 110209718
Burkholderia cepacia complex infection 104.83 11.03 45 378237 444 110210573
Cytomegalovirus nephritis 104.72 11.03 34 378248 137 110210880
Endocarditis 104.25 11.03 174 378108 13197 110197820
Pulmonary tuberculosis 104.19 11.03 142 378140 8997 110202020
SARS-CoV-2 RNA increased 103.76 11.03 35 378247 163 110210854
Cutaneous mucormycosis 102.35 11.03 50 378232 680 110210337
Oropharyngeal pain 101.93 11.03 192 378090 135084 110075933
Choriomeningitis lymphocytic 101.91 11.03 34 378248 152 110210865
Epstein Barr virus positive mucocutaneous ulcer 101.22 11.03 58 378224 1109 110209908
Urinoma 101.15 11.03 37 378245 228 110210789
Influenza like illness 101.00 11.03 92 378190 88320 110122697
Urosepsis 100.78 11.03 281 378001 30394 110180623
Intentional self-injury 100.71 11.03 7 378275 37422 110173595
Cytomegalovirus hepatitis 100.58 11.03 53 378229 853 110210164
Blood pressure fluctuation 100.54 11.03 66 378216 74758 110136259
Renal vein thrombosis 100.49 11.03 57 378225 1068 110209949
Eye infection toxoplasmal 100.44 11.03 50 378232 710 110210307
SARS-CoV-2 viraemia 100.15 11.03 32 378250 121 110210896
B-cell lymphoma 100.09 11.03 123 378159 7031 110203986
Coccidioidomycosis 99.97 11.03 65 378217 1572 110209445
Labelled drug-drug interaction medication error 99.82 11.03 272 378010 29030 110181987
Cutaneous blastomycosis 99.22 11.03 28 378254 60 110210957
Lupus vulgaris 98.45 11.03 4 378278 33879 110177138
Brain oedema 98.38 11.03 281 378001 30817 110180200
Choroiditis 98.31 11.03 64 378218 1551 110209466
Illness 98.11 11.03 82 378200 82089 110128928
Varicella 98.07 11.03 90 378192 3665 110207352
Candida sepsis 97.54 11.03 81 378201 2880 110208137
Leukoencephalopathy 97.54 11.03 138 378144 9057 110201960
Subcapsular renal haematoma 97.39 11.03 53 378229 913 110210104
Transplantation complication 97.08 11.03 42 378240 423 110210594
Herpes simplex pneumonia 97.07 11.03 40 378242 353 110210664
Acute respiratory failure 96.18 11.03 510 377772 74750 110136267
Hyperglycaemia 95.67 11.03 557 377725 84533 110126484
Diabetic ketoacidosis 95.48 11.03 339 377943 41719 110169298
Sebaceous carcinoma 95.39 11.03 32 378250 146 110210871
Orthostatic hypotension 95.20 11.03 54 378228 66195 110144822
Pneumonia necrotising 95.18 11.03 65 378217 1710 110209307
Lung consolidation 94.94 11.03 146 378136 10330 110200687
Neuropathy peripheral 94.64 11.03 306 377976 178971 110032046
Proteus infection 94.49 11.03 78 378204 2750 110208267
Fluid retention 94.30 11.03 110 378172 94197 110116820
Cytomegalovirus syndrome 94.02 11.03 37 378245 286 110210731
Arteritis infective 94.01 11.03 32 378250 154 110210863
Pain in jaw 93.95 11.03 29 378253 51148 110159869
Prescribed underdose 93.83 11.03 53 378229 65121 110145896
Muscle abscess 93.83 11.03 60 378222 1409 110209608
Cytomegalovirus gastroenteritis 93.69 11.03 47 378235 679 110210338
Renal abscess 93.10 11.03 61 378221 1495 110209522
Herpes zoster meningoencephalitis 91.96 11.03 53 378229 1025 110209992
Throat irritation 91.95 11.03 34 378248 53518 110157499
Haemodynamic instability 91.90 11.03 226 378056 22662 110188355
Dysgeusia 91.00 11.03 64 378218 69921 110141096
Hepatic artery stenosis 90.71 11.03 35 378247 255 110210762
Meningoencephalitis viral 90.69 11.03 42 378240 503 110210514
Fungaemia 90.63 11.03 108 378174 5978 110205039
Pyelonephritis fungal 90.20 11.03 36 378246 290 110210727
Granuloma 89.88 11.03 135 378147 9355 110201662
Thrombotic thrombocytopenic purpura 89.54 11.03 116 378166 6995 110204022
Injection site bruising 88.94 11.03 32 378250 51231 110159786
Joint injury 88.67 11.03 15 378267 39979 110171038
Device expulsion 88.58 11.03 4 378278 30887 110180130
Live birth 88.44 11.03 65 378217 69419 110141598
Blood creatine phosphokinase increased 88.39 11.03 72 378210 73005 110138012
Bronchiolitis obliterans syndrome 87.08 11.03 44 378238 646 110210371
Orf 86.82 11.03 24 378258 46 110210971
Bone pain 86.77 11.03 58 378224 65075 110145942
Pericardial effusion 86.76 11.03 407 377875 56810 110154207
Histoplasmosis cutaneous 86.65 11.03 25 378257 60 110210957
Oesophageal achalasia 86.57 11.03 50 378232 971 110210046
Disseminated strongyloidiasis 86.24 11.03 42 378240 567 110210450
Poisoning 86.06 11.03 3 378279 29102 110181915
Respiratory distress 85.48 11.03 463 377819 68411 110142606
Perinephric collection 85.24 11.03 37 378245 376 110210641
Mycobacterium chelonae infection 85.14 11.03 76 378206 2984 110208033
Pericarditis fungal 84.54 11.03 34 378248 280 110210737
Clostridial infection 84.40 11.03 106 378176 6196 110204821
Clostridium difficile infection 84.38 11.03 378 377904 51751 110159266
Toxic optic neuropathy 84.22 11.03 54 378228 1274 110209743
Angioedema 84.14 11.03 129 378153 98371 110112646
Abdominal infection 84.07 11.03 92 378190 4639 110206378
Blood potassium decreased 83.85 11.03 40 378242 54074 110156943
Brain herniation 83.83 11.03 126 378156 8737 110202280
Agitation 83.82 11.03 162 378120 112889 110098128
Wound dehiscence 83.73 11.03 119 378163 7843 110203174
Septic embolus 83.72 11.03 67 378215 2259 110208758
Respiratory syncytial virus infection 83.07 11.03 165 378117 14319 110196698
Muscle spasticity 82.95 11.03 12 378270 35903 110175114
Tuberculosis gastrointestinal 82.81 11.03 41 378241 575 110210442
International normalised ratio increased 82.75 11.03 105 378177 86667 110124350
Hypothyroidism 81.92 11.03 77 378205 72822 110138195
Tinnitus 81.89 11.03 53 378229 60487 110150530
Abscess fungal 81.72 11.03 37 378245 419 110210598
Meningitis bacterial 81.53 11.03 75 378207 3064 110207953
Abdominal pain 81.45 11.03 1249 377033 511740 109699277
Rash pruritic 81.33 11.03 131 378151 97938 110113079
Skin lesion 81.04 11.03 371 377911 51260 110159757
Device issue 81.03 11.03 11 378271 34524 110176493
Aspergilloma 81.00 11.03 44 378238 755 110210262
Nightmare 80.99 11.03 17 378265 38846 110172171
Portal vein thrombosis 80.97 11.03 110 378172 6948 110204069
Paraesthesia oral 80.75 11.03 10 378272 33661 110177356
Plasmablastic lymphoma 80.44 11.03 44 378238 766 110210251
Disability 80.31 11.03 6 378276 30217 110180800
Osteonecrosis of jaw 79.93 11.03 32 378250 47985 110163032
Device dislocation 79.61 11.03 8 378274 31696 110179321
Bone marrow failure 79.46 11.03 400 377882 57448 110153569
Metabolic acidosis 79.41 11.03 599 377683 99145 110111872
Reticulocytopenia 79.23 11.03 33 378249 300 110210717
Legionella infection 78.89 11.03 46 378236 910 110210107
Rhinorrhoea 78.86 11.03 144 378138 102522 110108495
Skin graft rejection 78.84 11.03 24 378258 74 110210943
Graft infection 78.79 11.03 43 378239 745 110210272
Lupus-like syndrome 78.78 11.03 21 378261 40771 110170246
Hepatic necrosis 78.54 11.03 130 378152 9792 110201225
Blood pressure decreased 78.50 11.03 173 378109 114918 110096099
Atrial fibrillation 78.44 11.03 462 377820 229180 109981837
Skin mass 78.22 11.03 129 378153 9687 110201330
Inferior vena cava stenosis 77.74 11.03 25 378257 97 110210920
Pancreatitis necrotising 77.64 11.03 95 378187 5406 110205611
Pulmonary embolism 77.29 11.03 424 377858 214050 109996967
Splenomegaly 77.14 11.03 221 378061 24277 110186740
Renal cell carcinoma 76.92 11.03 111 378171 7419 110203598
Human herpesvirus 6 infection reactivation 76.83 11.03 48 378234 1081 110209936
Renal tubular disorder 76.60 11.03 110 378172 7319 110203698
Urinary tract infection enterococcal 76.47 11.03 78 378204 3624 110207393
Histology abnormal 76.36 11.03 34 378248 369 110210648
Tuberculosis 76.19 11.03 180 378102 17594 110193423
Sopor 76.13 11.03 16 378266 36530 110174487
Klebsiella sepsis 75.96 11.03 82 378200 4071 110206946
Therapy partial responder 75.96 11.03 289 377993 36772 110174245
Encephalitis autoimmune 75.93 11.03 76 378206 3452 110207565
Vertigo 75.91 11.03 112 378170 86758 110124259
Meningitis viral 75.67 11.03 64 378218 2335 110208682
Joint dislocation 75.41 11.03 13 378269 34177 110176840
Vascular pseudoaneurysm 75.36 11.03 82 378200 4108 110206909
Anaphylactic reaction 75.36 11.03 175 378107 114125 110096892
Dermoid cyst 75.33 11.03 36 378246 465 110210552
Graft versus host disease in eye 75.15 11.03 35 378247 425 110210592
Solar lentigo 75.13 11.03 53 378229 1471 110209546
Muir-Torre syndrome 75.06 11.03 21 378261 43 110210974
Diaphragmatic hernia 74.07 11.03 38 378244 577 110210440
Disseminated varicella zoster vaccine virus infection 73.99 11.03 26 378256 140 110210877
Transient ischaemic attack 73.77 11.03 66 378216 63916 110147101
Anti-erythropoietin antibody negative 73.65 11.03 31 378251 290 110210727
Poisoning deliberate 73.62 11.03 4 378278 26327 110184690
Death 73.60 11.03 1824 376458 697045 109513972
Fungal sepsis 73.29 11.03 61 378221 2176 110208841
Swelling face 73.16 11.03 127 378155 92194 110118823
Drug level below therapeutic 73.08 11.03 138 378144 11535 110199482
Urinary tract infection viral 73.03 11.03 23 378259 82 110210935
Cardio-respiratory arrest 72.70 11.03 182 378100 115654 110095363
Anaphylactic shock 72.67 11.03 43 378239 51503 110159514
Rhabdomyolysis 72.62 11.03 193 378089 120208 110090809
Hyperglycaemic hyperosmolar nonketotic syndrome 72.58 11.03 69 378213 2940 110208077
Dysplasia 72.49 11.03 56 378226 1792 110209225
Enterococcal sepsis 72.48 11.03 72 378210 3240 110207777
Diffuse alveolar damage 72.44 11.03 79 378203 3968 110207049
Hepatitis cholestatic 72.18 11.03 175 378107 17391 110193626
Chronic hepatitis C 72.17 11.03 39 378243 662 110210355
Ear infection 71.98 11.03 65 378217 62667 110148350
Serum sickness 71.98 11.03 82 378200 4324 110206693
Lip swelling 71.80 11.03 42 378240 50625 110160392
Herpes simplex oesophagitis 71.78 11.03 34 378248 430 110210587
Malignant fibrous histiocytoma 71.37 11.03 29 378253 246 110210771
Impaired work ability 70.91 11.03 5 378277 26414 110184603
Encephalitis cytomegalovirus 70.85 11.03 56 378226 1854 110209163
Unevaluable event 70.83 11.03 59 378223 59168 110151849
Epilepsy 70.53 11.03 148 378134 100061 110110956
Shock 70.43 11.03 366 377916 53222 110157795
Flatulence 70.06 11.03 46 378236 52103 110158914
Erythema 69.94 11.03 648 377634 290799 109920218
Lung abscess 69.84 11.03 86 378196 4926 110206091
Gastritis fungal 69.53 11.03 30 378252 300 110210717
Dengue fever 69.36 11.03 48 378234 1291 110209726
Abdominal wall abscess 69.11 11.03 51 378231 1521 110209496
Ureteral necrosis 68.89 11.03 22 378260 83 110210934
Engraft failure 68.84 11.03 40 378242 786 110210231
Graft ischaemia 68.80 11.03 24 378258 126 110210891
Sleep disorder due to general medical condition, insomnia type 68.65 11.03 163 378119 105480 110105537
C3 glomerulopathy 68.62 11.03 25 378257 152 110210865
Cytopenia 68.58 11.03 243 378039 29873 110181144
Blood pressure diastolic decreased 68.31 11.03 19 378263 35866 110175151
Vesicoureteric reflux 67.91 11.03 26 378256 185 110210832
Disseminated paracoccidioidomycosis 67.86 11.03 17 378265 17 110211000
Metastases to lung 67.78 11.03 203 378079 22860 110188157
Red blood cell sedimentation rate abnormal 67.67 11.03 4 378278 24505 110186512
Body temperature decreased 67.67 11.03 21 378261 36914 110174103
Staphylococcal sepsis 67.61 11.03 170 378112 17284 110193733
Wound infection 67.45 11.03 143 378139 96322 110114695
Heartland virus infection 66.89 11.03 17 378265 19 110210998
Biloma 66.86 11.03 27 378255 225 110210792
Splenic abscess 66.75 11.03 42 378240 958 110210059
Intestinal tuberculosis 66.71 11.03 28 378254 260 110210757
Intentional product use issue 66.70 11.03 535 377747 247371 109963646
Intracranial pressure increased 66.52 11.03 125 378157 10410 110200607
Viral load 66.36 11.03 20 378262 59 110210958
MELAS syndrome 66.35 11.03 29 378253 300 110210717
Parvovirus infection 66.15 11.03 41 378241 910 110210107
Glomerulonephritis proliferative 66.14 11.03 33 378249 471 110210546
Urinary tract infection 66.12 11.03 1521 376761 324761 109886256
Atypical mycobacterial pneumonia 66.10 11.03 29 378253 303 110210714
Chronic inflammatory demyelinating polyradiculoneuropathy 66.05 11.03 57 378225 2138 110208879
Lymphocytic infiltration 65.89 11.03 55 378227 1970 110209047
Parainfluenzae virus infection 65.75 11.03 99 378183 6875 110204142
Disseminated trichosporonosis 65.63 11.03 26 378256 205 110210812
Ventricular remodelling 65.59 11.03 23 378259 123 110210894
Hallucination 65.51 11.03 157 378125 101275 110109742
Gastroenteritis Escherichia coli 65.39 11.03 46 378236 1271 110209746
Dysplastic naevus 65.25 11.03 39 378243 809 110210208
Drug level changed 65.25 11.03 35 378247 585 110210432
Thyroid gland abscess 65.20 11.03 21 378261 82 110210935
Hepatitis viral 65.18 11.03 48 378234 1427 110209590
Erythema infectiosum 65.09 11.03 26 378256 210 110210807
Cardiac disorder 65.05 11.03 100 378182 76180 110134837
Escherichia sepsis 65.01 11.03 122 378160 10150 110200867
Product label confusion 64.82 11.03 3 378279 22674 110188343
Skin squamous cell carcinoma metastatic 64.80 11.03 21 378261 84 110210933
Postoperative wound infection 64.79 11.03 157 378125 15596 110195421
Cytokine storm 64.74 11.03 48 378234 1442 110209575
Gastroenteritis adenovirus 64.35 11.03 31 378251 408 110210609
Tachycardia 64.30 11.03 482 377800 226163 109984854
Malacoplakia vesicae 64.01 11.03 20 378262 69 110210948
Drug withdrawal syndrome 63.93 11.03 25 378257 38029 110172988
Heart rate irregular 63.68 11.03 19 378263 34255 110176762
Adverse reaction 63.65 11.03 12 378270 29582 110181435
Post procedural urine leak 63.53 11.03 23 378259 137 110210880
Drug dependence 63.39 11.03 47 378235 49973 110161044
Complications of bone marrow transplant 63.30 11.03 35 378247 623 110210394
Diffuse large B-cell lymphoma stage IV 63.19 11.03 39 378243 859 110210158
Bone marrow transplant rejection 63.12 11.03 28 378254 301 110210716
Neutropenia 63.03 11.03 1703 376579 372917 109838100
Gastrointestinal fungal infection 63.01 11.03 37 378245 742 110210275
Sinus disorder 62.92 11.03 17 378265 32711 110178306
Normocytic anaemia 62.68 11.03 93 378189 6374 110204643
Enteritis 62.45 11.03 175 378107 18981 110192036
Gastrointestinal disorder 62.43 11.03 528 377754 241424 109969593
Emotional distress 62.39 11.03 38 378244 44809 110166208
Large intestine perforation 62.37 11.03 160 378122 16469 110194548
T-cell lymphoma 62.35 11.03 48 378234 1528 110209489
Breath sounds abnormal 62.27 11.03 7 378275 25397 110185620
Limb discomfort 62.08 11.03 31 378251 40823 110170194
Device related infection 62.04 11.03 284 377998 39235 110171782
Renal cortical necrosis 62.02 11.03 32 378250 492 110210525
Renal arteriosclerosis 62.02 11.03 32 378250 492 110210525
Cognitive disorder 61.79 11.03 129 378153 87382 110123635
Odynophagia 61.75 11.03 144 378138 13957 110197060
Hepatic artery aneurysm 61.71 11.03 20 378262 80 110210937
Renal disorder 61.65 11.03 333 377949 49146 110161871
Glomerulonephritis rapidly progressive 61.60 11.03 55 378227 2160 110208857
Delirium 61.60 11.03 245 378037 134780 110076237
Dehydration 61.37 11.03 635 377647 278876 109932141
Eczema herpeticum 61.36 11.03 31 378251 455 110210562
Empyema 61.17 11.03 85 378197 5485 110205532
Feeling cold 61.07 11.03 20 378262 33967 110177050
Mycobacterium marinum infection 61.00 11.03 36 378246 729 110210288
Mycotic endophthalmitis 60.89 11.03 30 378252 416 110210601
Neoplasm progression 60.73 11.03 79 378203 64516 110146501
Renal necrosis 60.72 11.03 27 378255 292 110210725
Burning sensation 60.70 11.03 89 378193 69123 110141894
Herpes virus infection 60.25 11.03 107 378175 8531 110202486
Disturbance in attention 60.18 11.03 74 378208 61921 110149096
Urinary fistula 59.84 11.03 20 378262 90 110210927
Haematochezia 59.70 11.03 199 378083 115325 110095692
Presyncope 59.33 11.03 48 378234 48839 110162178
Optic atrophy 59.28 11.03 57 378225 2464 110208553
Back disorder 59.06 11.03 3 378279 20919 110190098
Dyspnoea exertional 58.90 11.03 172 378110 103888 110107129
Liver function test increased 58.83 11.03 135 378147 88413 110122604
Pancreatitis haemorrhagic 58.77 11.03 39 378243 977 110210040
Trench fever 58.29 11.03 17 378265 43 110210974
Platelet count decreased 58.06 11.03 506 377776 229937 109981080
Ecthyma 57.98 11.03 39 378243 1000 110210017
Babesiosis 57.93 11.03 30 378252 465 110210552
Chills 57.60 11.03 398 377884 190182 110020835
Apoptosis 57.45 11.03 34 378248 692 110210325
Chimerism 57.38 11.03 26 378256 295 110210722
Cutaneous T-cell lymphoma 57.02 11.03 64 378218 3320 110207697
Cholestasis 56.84 11.03 397 377885 64121 110146896
Adult T-cell lymphoma/leukaemia 56.72 11.03 28 378254 390 110210627
Microangiopathy 56.69 11.03 60 378222 2912 110208105
Hepatosplenic T-cell lymphoma 56.68 11.03 38 378244 969 110210048
Injection site swelling 56.63 11.03 77 378205 61713 110149304
Pneumopericardium 56.61 11.03 24 378258 229 110210788
Injection site pruritus 56.59 11.03 55 378227 51203 110159814
Nosocomial infection 56.48 11.03 62 378220 3137 110207880
Pleocytosis 56.46 11.03 47 378235 1677 110209340
Primary effusion lymphoma 56.19 11.03 17 378265 51 110210966
Anastomotic stenosis 56.14 11.03 33 378249 663 110210354
Meningitis fungal 56.02 11.03 26 378256 313 110210704
Pneumonia influenzal 55.80 11.03 67 378215 3738 110207279
Respiratory tract congestion 55.72 11.03 18 378264 30839 110180178
Drug tolerance decreased 55.47 11.03 13 378269 27527 110183490
Emphysematous cystitis 55.42 11.03 32 378250 621 110210396
Intracranial infection 55.37 11.03 26 378256 322 110210695
Sporotrichosis 55.26 11.03 20 378262 119 110210898
Urinary tract candidiasis 55.21 11.03 40 378242 1159 110209858
Aggression 55.06 11.03 73 378209 59137 110151880
Renal-limited thrombotic microangiopathy 55.06 11.03 30 378252 518 110210499
Immunosuppression 54.75 11.03 159 378123 17600 110193417
Infectious thyroiditis 54.62 11.03 22 378260 182 110210835
Toxic encephalopathy 54.61 11.03 144 378138 15070 110195947
Cardiac infection 54.44 11.03 32 378250 643 110210374
Adenovirus reactivation 54.27 11.03 33 378249 707 110210310
Colitis 54.20 11.03 562 377720 101761 110109256
Cold sweat 54.18 11.03 6 378276 22025 110188992
Tularaemia 54.10 11.03 22 378260 187 110210830
Rheumatoid nodule 54.01 11.03 4 378278 20292 110190725
Head injury 53.77 11.03 41 378241 42976 110168041
Photosensitivity reaction 53.64 11.03 201 378081 25388 110185629
Abortion spontaneous 53.55 11.03 246 378036 34036 110176981
Angiocentric lymphoma 53.52 11.03 40 378242 1217 110209800
Left ventricular hypertrophy 53.41 11.03 131 378151 13113 110197904
Pneumonia pneumococcal 53.38 11.03 75 378207 4890 110206127
Arterial rupture 53.30 11.03 35 378247 861 110210156
Metapneumovirus infection 53.25 11.03 53 378229 2391 110208626
Haemolysis 53.09 11.03 145 378137 15494 110195523
Respiratory arrest 53.08 11.03 73 378209 58226 110152791
Enterocolitis 53.07 11.03 164 378118 18785 110192232
Hip fracture 52.92 11.03 27 378255 35124 110175893
Sinus congestion 52.86 11.03 19 378263 30440 110180577
Blood immunoglobulin G decreased 52.83 11.03 78 378204 5322 110205695
Portal hypertension 52.71 11.03 101 378181 8536 110202481
Eccrine carcinoma 52.39 11.03 14 378268 22 110210995
Fungal abscess central nervous system 52.35 11.03 22 378260 205 110210812
Serotonin syndrome 51.94 11.03 76 378206 59077 110151940
Blood creatine increased 51.93 11.03 119 378163 11402 110199615
Prostatic abscess 51.92 11.03 30 378252 583 110210434
Oedematous kidney 51.87 11.03 23 378259 247 110210770
Aplastic anaemia 51.84 11.03 192 378090 24116 110186901
Injection site haemorrhage 51.81 11.03 24 378258 33004 110178013
Respiratory tract infection fungal 51.67 11.03 40 378242 1284 110209733
Overdose 51.37 11.03 531 377751 233263 109977754
Pulmonary mass 51.28 11.03 258 378024 37043 110173974
Hepatosplenomegaly 51.24 11.03 88 378194 6831 110204186
Abdominal abscess 51.22 11.03 101 378181 8718 110202299
Gastrointestinal toxicity 51.19 11.03 116 378166 11032 110199985
Blood test abnormal 50.96 11.03 17 378265 28537 110182480
Meningomyelitis herpes 50.95 11.03 17 378265 76 110210941
Subcutaneous abscess 50.88 11.03 104 378178 9213 110201804
Hepatic vein occlusion 50.84 11.03 24 378258 301 110210716
Acarodermatitis 50.81 11.03 47 378235 1934 110209083
Depressed mood 50.63 11.03 81 378201 60728 110150289
Intussusception 50.63 11.03 43 378239 1578 110209439
Thrombocytopenia 50.40 11.03 1556 376726 347329 109863688
Walking aid user 50.18 11.03 12 378270 25063 110185954
Dysstasia 50.17 11.03 25 378257 32961 110178056
Palmar-plantar erythrodysaesthesia syndrome 50.14 11.03 40 378242 40985 110170032
Ear pain 50.14 11.03 65 378217 53161 110157856
Hepatitis B reactivation 50.02 11.03 91 378191 7393 110203624
Potentiating drug interaction 50.00 11.03 118 378164 11525 110199492
Renal haemorrhage 49.99 11.03 52 378230 2473 110208544
Phaeohyphomycotic brain abscess 49.97 11.03 16 378266 61 110210956
Crying 49.86 11.03 13 378269 25615 110185402
Toxic skin eruption 49.78 11.03 16 378266 27499 110183518
Weight fluctuation 49.77 11.03 8 378274 22137 110188880
Biopsy kidney abnormal 49.49 11.03 20 378262 167 110210850
Cytomegalovirus duodenitis 49.41 11.03 19 378263 137 110210880
Troponin increased 49.28 11.03 20 378262 29746 110181271
Bone tuberculosis 49.27 11.03 31 378251 707 110210310
Incorrect route of product administration 49.06 11.03 90 378192 63971 110147046
Respiratory depression 49.05 11.03 24 378258 31977 110179040
Coordination abnormal 48.70 11.03 13 378269 25215 110185802
Hyperuricaemia 48.61 11.03 134 378148 14397 110196620
Infusion site reaction 48.48 11.03 3 378279 17679 110193338
Pneumonia staphylococcal 48.47 11.03 80 378202 6011 110205006
Systemic bacterial infection 48.40 11.03 15 378267 50 110210967
Metastatic malignant melanoma 48.32 11.03 59 378223 3350 110207667
Chronic sinusitis 48.28 11.03 13 378269 25071 110185946
Angina pectoris 48.17 11.03 87 378195 62208 110148809
Pallor 48.17 11.03 74 378208 56393 110154624
Neutralising antibodies negative 48.10 11.03 11 378271 4 110211013
Coeliac disease 48.07 11.03 46 378236 43141 110167876
Pancreatitis acute 47.99 11.03 362 377920 59912 110151105
Haemosiderosis 47.93 11.03 28 378254 556 110210461
Osteoporosis 47.92 11.03 146 378136 87006 110124011
Prostatitis 47.92 11.03 70 378212 4731 110206286
Poor quality sleep 47.91 11.03 18 378264 28059 110182958
Vascular graft complication 47.90 11.03 20 378262 183 110210834
Renal tuberculosis 47.87 11.03 16 378266 72 110210945
Immunosuppressant drug level 47.70 11.03 13 378269 23 110210994
Splenic vein thrombosis 47.66 11.03 34 378248 961 110210056
Speech disorder 47.60 11.03 86 378196 61483 110149534
Blood pressure systolic abnormal 47.60 11.03 13 378269 24837 110186180
Pulmonary haemorrhage 47.56 11.03 144 378138 16312 110194705
Sputum discoloured 47.54 11.03 18 378264 27927 110183090
Sarcoma of skin 47.52 11.03 16 378266 74 110210943
Scleroderma 47.42 11.03 81 378201 6260 110204757
Serratia infection 47.40 11.03 48 378234 2211 110208806
Drug-induced liver injury 47.39 11.03 230 378052 119837 110091180
Miosis 47.10 11.03 9 378273 21974 110189043
Rebound effect 47.04 11.03 134 378148 14672 110196345
Panic attack 47.01 11.03 20 378262 28920 110182097
Viral load increased 46.97 11.03 58 378224 3332 110207685
Hepatic infection fungal 46.87 11.03 23 378259 316 110210701
Hepatitis C RNA increased 46.81 11.03 25 378257 414 110210603
Restlessness 46.79 11.03 75 378207 56184 110154833
Squamous cell carcinoma of the oral cavity 46.78 11.03 30 378252 708 110210309
Metastases to lymph nodes 46.74 11.03 135 378147 14897 110196120
Osteomyelitis 46.74 11.03 248 378034 36352 110174665
Laboratory test abnormal 46.72 11.03 49 378233 44030 110166987
Bronchial anastomosis complication 46.71 11.03 17 378265 103 110210914
Endocarditis bacterial 46.63 11.03 43 378239 1762 110209255
Anaplastic large cell lymphoma T- and null-cell types 46.62 11.03 20 378262 197 110210820
Acute hepatitis C 46.60 11.03 22 378260 276 110210741
Disseminated coccidioidomycosis 46.60 11.03 21 378261 235 110210782
Peritonitis bacterial 46.60 11.03 108 378174 10425 110200592
Coronary artery disease 46.26 11.03 111 378171 71579 110139438
Scrotal ulcer 46.23 11.03 25 378257 425 110210592
Nervousness 46.22 11.03 35 378247 36816 110174201
Calciphylaxis 46.14 11.03 64 378218 4123 110206894
Epstein-Barr virus antibody positive 46.11 11.03 29 378253 661 110210356
Dehiscence 46.05 11.03 30 378252 728 110210289
Gestational hypertension 46.02 11.03 47 378235 2187 110208830
Morganella infection 46.00 11.03 38 378244 1341 110209676
Endothelial dysfunction 45.99 11.03 23 378259 330 110210687
Vision blurred 45.96 11.03 256 378026 128766 110082251
Granulomatous rosacea 45.84 11.03 20 378262 206 110210811
Oesophageal perforation 45.76 11.03 41 378241 1618 110209399
Corneal endotheliitis 45.64 11.03 17 378265 111 110210906
Visual impairment 45.59 11.03 271 378011 134157 110076860
Retinitis 45.52 11.03 27 378255 32300 110178717
Dyslipidaemia 45.48 11.03 139 378143 15826 110195191
Diffuse mesangial sclerosis 45.33 11.03 15 378267 65 110210952
Fungal peritonitis 45.22 11.03 37 378245 1288 110209729
Endocarditis staphylococcal 45.16 11.03 34 378248 1046 110209971
Viral vasculitis 45.09 11.03 20 378262 215 110210802
Sinusitis fungal 45.08 11.03 51 378231 2669 110208348
Abscess 45.06 11.03 200 378082 27269 110183748
Superinfection 44.93 11.03 75 378207 5688 110205329
Hypoacusis 44.68 11.03 33 378249 35158 110175859
Multiple sclerosis 44.65 11.03 16 378266 25682 110185335
Upper respiratory fungal infection 44.64 11.03 24 378258 403 110210614
Bacteriuria 44.61 11.03 38 378244 1400 110209617
Hypertrophic osteoarthropathy 44.52 11.03 17 378265 120 110210897
Neuroleptic malignant syndrome 44.47 11.03 31 378251 34028 110176989
Stevens-Johnson syndrome 44.46 11.03 57 378225 46844 110164173
Dialysis 44.41 11.03 158 378124 19461 110191556
Diarrhoea haemorrhagic 44.40 11.03 136 378146 15503 110195514
Transplant 44.38 11.03 36 378246 1238 110209779
Meningoencephalitis amoebic 44.37 11.03 20 378262 224 110210793
Alpha haemolytic streptococcal infection 44.29 11.03 58 378224 3535 110207482
Device malfunction 44.26 11.03 16 378266 25542 110185475
Acute generalised exanthematous pustulosis 44.08 11.03 10 378272 21654 110189363
Mouth ulceration 44.06 11.03 299 377983 47839 110163178
Tooth disorder 43.93 11.03 23 378259 29486 110181531
Central nervous system vasculitis 43.89 11.03 40 378242 1614 110209403
Lupus nephritis 43.88 11.03 66 378216 4579 110206438
Obstructive airways disorder 43.84 11.03 56 378226 46093 110164924
Skin squamous cell carcinoma recurrent 43.82 11.03 16 378266 98 110210919
Renal and pancreas transplant rejection 43.80 11.03 14 378268 53 110210964
Panophthalmitis 43.78 11.03 19 378263 193 110210824
Skin laceration 43.70 11.03 31 378251 33722 110177295
Intervertebral disc protrusion 43.64 11.03 20 378262 27678 110183339
Acute pulmonary histoplasmosis 43.62 11.03 21 378261 276 110210741
Affect lability 43.58 11.03 6 378276 18631 110192386
Cytomegalovirus urinary tract infection 43.55 11.03 16 378266 100 110210917
Needle issue 43.52 11.03 5 378277 17835 110193182
Peritonitis pneumococcal 43.41 11.03 12 378270 23 110210994
Meningitis 43.27 11.03 112 378170 11590 110199427
Herpes zoster oticus 43.25 11.03 28 378254 672 110210345
Femur fracture 43.25 11.03 53 378229 44416 110166601
Pleural mesothelioma malignant 43.18 11.03 18 378264 164 110210853
Evans syndrome 43.13 11.03 29 378253 743 110210274
Withdrawal syndrome 43.08 11.03 27 378255 31353 110179664
Herpes simplex test positive 43.02 11.03 27 378255 613 110210404
Metastases to salivary gland 42.96 11.03 15 378267 79 110210938
Nephritis 42.88 11.03 76 378206 6050 110204967
Emphysematous cholecystitis 42.76 11.03 16 378266 106 110210911
Body temperature increased 42.68 11.03 76 378206 54637 110156380
Haemothorax 42.63 11.03 82 378200 6949 110204068
Superinfection viral 42.62 11.03 14 378268 59 110210958
Ureteritis 42.57 11.03 20 378262 248 110210769
Hypoalbuminaemia 42.39 11.03 204 378078 28770 110182247
Dyskinesia 42.39 11.03 69 378213 51377 110159640
Glomerulonephropathy 42.26 11.03 22 378260 345 110210672
Streptococcal bacteraemia 42.21 11.03 65 378217 4604 110206413
Lymphadenitis fungal 42.13 11.03 12 378270 27 110210990
Macular degeneration 42.11 11.03 11 378271 21648 110189369
Isosporiasis 42.07 11.03 18 378264 176 110210841
Pseudohypoaldosteronism 42.07 11.03 14 378268 62 110210955
Hyperoxaluria 41.92 11.03 22 378260 351 110210666
Lethargy 41.91 11.03 171 378111 93405 110117612
Myopathy 41.91 11.03 183 378099 24777 110186240
Neuralgia 41.87 11.03 63 378219 48415 110162602
Campylobacter infection 41.82 11.03 46 378236 2333 110208684
Yersinia infection 41.77 11.03 16 378266 114 110210903
Throat tightness 41.75 11.03 32 378250 33457 110177560
Escherichia pyelonephritis 41.68 11.03 31 378251 936 110210081
Catatonia 41.63 11.03 108 378174 11192 110199825
Hepatic function abnormal 41.55 11.03 478 377804 88817 110122200
Myelitis 41.38 11.03 53 378229 3160 110207857
Lymphadenitis bacterial 41.34 11.03 15 378267 90 110210927
Akathisia 41.24 11.03 5 378277 17108 110193909
Labelled drug-drug interaction issue 41.23 11.03 60 378222 4041 110206976
Hepatic cancer recurrent 41.22 11.03 21 378261 314 110210703
Cholelithiasis 41.08 11.03 98 378184 63324 110147693
Delayed engraftment 40.94 11.03 20 378262 272 110210745
Cutaneous leishmaniasis 40.73 11.03 22 378260 373 110210644
Solid organ transplant rejection 40.72 11.03 13 378269 49 110210968
Postoperative thoracic procedure complication 40.69 11.03 14 378268 70 110210947
Nodular regenerative hyperplasia 40.49 11.03 38 378244 1593 110209424
Device leakage 40.42 11.03 4 378278 16044 110194973
Eating disorder 40.41 11.03 28 378254 30830 110180187
Hiatus hernia 40.39 11.03 22 378260 27584 110183433
Listeriosis 40.37 11.03 49 378233 2765 110208252
Vasogenic cerebral oedema 40.28 11.03 44 378238 2214 110208803
Hyperparathyroidism secondary 40.21 11.03 53 378229 3251 110207766
Liver disorder 40.09 11.03 303 377979 141940 110069077
Injection site mass 40.00 11.03 17 378265 24596 110186421
Mood swings 39.98 11.03 14 378268 22798 110188219
Granulomatous dermatitis 39.98 11.03 24 378258 502 110210515
Rib fracture 39.94 11.03 34 378248 33736 110177281
Bone marrow transplant 39.92 11.03 38 378244 1622 110209395
Complications of transplanted pancreas 39.91 11.03 12 378270 35 110210982
Azotaemia 39.87 11.03 99 378183 9986 110201031
Pericarditis constrictive 39.80 11.03 31 378251 1004 110210013
Viral diarrhoea 39.78 11.03 25 378257 569 110210448
Zoonotic bacterial infection 39.75 11.03 14 378268 76 110210941
Herpes zoster cutaneous disseminated 39.68 11.03 24 378258 509 110210508
Pneumothorax 39.66 11.03 231 378051 35054 110175963
Limbic encephalitis 39.60 11.03 28 378254 780 110210237
Porphyria acute 39.58 11.03 8 378274 18772 110192245
Muscle twitching 39.41 11.03 27 378255 29908 110181109
Central nervous system lesion 39.36 11.03 130 378152 15423 110195594
Ulcer haemorrhage 39.31 11.03 14 378268 22557 110188460
Gastroenteritis rotavirus 39.25 11.03 25 378257 583 110210434
Dysphagia 39.24 11.03 336 377946 153264 110057753
Hepatitis C virus test 39.17 11.03 13 378269 57 110210960
Aspartate aminotransferase increased 39.03 11.03 354 377928 159582 110051435
Aortic pseudoaneurysm 39.01 11.03 14 378268 81 110210936
Toxic epidermal necrolysis 38.90 11.03 85 378197 56642 110154375
Blood iron decreased 38.83 11.03 9 378273 19205 110191812
Nocardia sepsis 38.81 11.03 13 378269 59 110210958
Subcutaneous emphysema 38.72 11.03 46 378236 2538 110208479
Immune thrombocytopenia 38.60 11.03 166 378116 22328 110188689
Arterial haemorrhage 38.58 11.03 56 378226 3763 110207254
Peliosis hepatis 38.55 11.03 17 378265 180 110210837
Cytokine release syndrome 38.49 11.03 118 378164 70188 110140829
Breast cancer 38.48 11.03 45 378237 38497 110172520
Onychomycosis 38.45 11.03 45 378237 38486 110172531
Mental status changes 38.39 11.03 414 377868 75708 110135309
Molluscum contagiosum 38.36 11.03 25 378257 607 110210410
Urine output decreased 38.29 11.03 152 378130 19724 110191293
Mycobacterial peritonitis 38.19 11.03 18 378264 225 110210792
Lymph node tuberculosis 38.04 11.03 31 378251 1073 110209944
Drug eruption 37.96 11.03 79 378203 53580 110157437
Porokeratosis 37.91 11.03 19 378263 274 110210743
Lymphadenopathy 37.88 11.03 359 377923 63476 110147541
Pneumonia herpes viral 37.82 11.03 17 378265 189 110210828
Basal cell carcinoma 37.81 11.03 275 378007 44995 110166022
Carpal tunnel syndrome 37.74 11.03 15 378267 22595 110188422
Pasteurella infection 37.71 11.03 16 378266 153 110210864
Cataract 37.67 11.03 142 378140 79343 110131674
Cutaneous tuberculosis 37.66 11.03 19 378263 278 110210739
Pyuria 37.60 11.03 46 378236 2617 110208400
Infusion site pain 37.60 11.03 7 378275 17412 110193605
Substance-induced psychotic disorder 37.59 11.03 67 378215 5357 110205660
Encephalomyelitis 37.57 11.03 20 378262 329 110210688
Limb injury 37.51 11.03 44 378238 37592 110173425
Choking 37.45 11.03 4 378278 15106 110195911
Urinary tract infection pseudomonal 37.40 11.03 42 378240 2180 110208837
Parvovirus B19 infection reactivation 37.39 11.03 11 378271 29 110210988
Renal aneurysm 37.36 11.03 19 378263 283 110210734
Hypersomnia 37.36 11.03 25 378257 28036 110182981
Red blood cell count decreased 37.28 11.03 109 378173 65814 110145203
Therapy interrupted 37.27 11.03 71 378211 49751 110161266
Mycobacterium kansasii infection 37.24 11.03 21 378261 389 110210628
Arrhythmia 37.23 11.03 118 378164 69457 110141560
Cryptococcal fungaemia 37.18 11.03 19 378263 286 110210731
Bladder transitional cell carcinoma 37.13 11.03 47 378235 2769 110208248
Localised infection 37.12 11.03 56 378226 42992 110168025
Paranoia 37.09 11.03 15 378267 22359 110188658
Non-cirrhotic portal hypertension 37.06 11.03 26 378256 715 110210302
Pseudomonal bacteraemia 36.95 11.03 59 378223 4312 110206705
Anorexia nervosa 36.83 11.03 19 378263 292 110210725
Renal injury 36.77 11.03 144 378138 18569 110192448
Purpura fulminans 36.72 11.03 20 378262 345 110210672
Gallbladder rupture 36.69 11.03 32 378250 1218 110209799
Cytomegalovirus gastrointestinal ulcer 36.64 11.03 15 378267 130 110210887
Papule 36.46 11.03 96 378186 10037 110200980
Urate nephropathy 36.31 11.03 17 378265 209 110210808
Herpes zoster reactivation 36.30 11.03 21 378261 409 110210608
Anger 36.30 11.03 10 378272 18997 110192020
Hepatic angiosarcoma 36.29 11.03 14 378268 102 110210915
Head discomfort 36.28 11.03 10 378272 18990 110192027
Renal artery thrombosis 36.27 11.03 23 378259 532 110210485
Cholangiocarcinoma 36.23 11.03 47 378235 2838 110208179
Renal vessel disorder 36.21 11.03 19 378263 303 110210714
Endocarditis enterococcal 36.12 11.03 20 378262 357 110210660
H1N1 influenza 36.09 11.03 48 378234 2970 110208047
Blood glucose increased 36.05 11.03 285 377997 132211 110078806
Extranodal marginal zone B-cell lymphoma (MALT type) 35.98 11.03 26 378256 750 110210267
Blood beta-D-glucan increased 35.78 11.03 26 378256 757 110210260
Inflammatory myofibroblastic tumour 35.75 11.03 17 378265 217 110210800
Blood pressure diastolic abnormal 35.74 11.03 22 378260 25793 110185224
Electrocardiogram QT prolonged 35.72 11.03 222 378060 108738 110102279
Granulomatous liver disease 35.72 11.03 35 378247 1549 110209468
Abdominal wall infection 35.67 11.03 15 378267 140 110210877
Bartonellosis 35.64 11.03 11 378271 36 110210981
Hypertriglyceridaemia 35.63 11.03 129 378153 16025 110194992
Human herpes virus 8 test positive 35.55 11.03 12 378270 56 110210961
Salivary hypersecretion 35.53 11.03 8 378274 17413 110193604
Erythropoiesis abnormal 35.49 11.03 24 378258 621 110210396
Injection site warmth 35.48 11.03 8 378274 17397 110193620
Pneumonia viral 35.47 11.03 101 378181 11056 110199961
Haematemesis 35.45 11.03 95 378187 59013 110152004
Encephalomalacia 35.39 11.03 34 378248 1468 110209549
Transplant abscess 35.38 11.03 12 378270 57 110210960
Tracheobronchitis 35.29 11.03 45 378237 2671 110208346
Human T-cell lymphotropic virus type I infection 35.27 11.03 14 378268 111 110210906
Plasmacytoma 35.19 11.03 64 378218 5198 110205819
Type III immune complex mediated reaction 35.09 11.03 29 378253 1024 110209993
Papilloedema 35.03 11.03 78 378204 7331 110203686
Hydrocephalus 35.03 11.03 96 378186 10279 110200738
Nephritis haemorrhagic 34.98 11.03 9 378273 11 110211006
Pharyngeal polyp 34.98 11.03 9 378273 11 110211006
Acinetobacter bacteraemia 34.93 11.03 19 378263 327 110210690
Viral uveitis 34.82 11.03 16 378266 188 110210829
Soft tissue mass 34.80 11.03 34 378248 1499 110209518
Giardiasis 34.77 11.03 23 378259 573 110210444
Appendicolith 34.76 11.03 4 378278 14251 110196766
Gastrointestinal lymphoma 34.75 11.03 17 378265 232 110210785
Renal haematoma 34.71 11.03 28 378254 955 110210062
Hypoaldosteronism 34.69 11.03 24 378258 645 110210372
Genital herpes simplex 34.65 11.03 22 378260 510 110210507
Faeces discoloured 34.58 11.03 39 378243 33909 110177108
Orchitis 34.47 11.03 37 378245 1825 110209192
Hyponatraemia 34.45 11.03 530 377752 217123 109993894
Pulmonary cavitation 34.44 11.03 40 378242 2154 110208863
Gastroenteritis 34.32 11.03 239 378043 38561 110172456
Chemical peritonitis 34.31 11.03 18 378264 287 110210730
Glomerulonephritis minimal lesion 34.19 11.03 29 378253 1062 110209955
Toothache 34.18 11.03 19 378263 23556 110187461
Retinal haemorrhage 34.18 11.03 90 378192 9411 110201606
Renal cyst haemorrhage 34.16 11.03 25 378257 736 110210281
Irritability 34.15 11.03 70 378212 47739 110163278
Morphoea 34.01 11.03 23 378259 595 110210422
Cholangitis sclerosing 33.99 11.03 51 378231 3531 110207486
Tongue ulceration 33.98 11.03 60 378222 4762 110206255
Infective pulmonary exacerbation of cystic fibrosis 33.96 11.03 5 378277 14766 110196251
Parosmia 33.96 11.03 3 378279 13177 110197840
Seronegative arthritis 33.95 11.03 3 378279 13174 110197843
Disseminated varicella 33.94 11.03 11 378271 44 110210973
Genitourinary tract infection 33.92 11.03 18 378264 294 110210723
Bronchospasm 33.90 11.03 32 378250 30207 110180810
Productive cough 33.89 11.03 240 378042 114065 110096952
Product complaint 33.87 11.03 4 378278 13968 110197049
Gastric ulcer 33.87 11.03 243 378039 39584 110171433
Ureteric anastomosis complication 33.82 11.03 10 378272 27 110210990
Eye infection fungal 33.78 11.03 23 378259 602 110210415
Leiomyosarcoma 33.76 11.03 20 378262 408 110210609
Kidney rupture 33.74 11.03 17 378265 248 110210769
Nephrosclerosis 33.67 11.03 38 378244 1983 110209034
Penile ulceration 33.65 11.03 24 378258 678 110210339
Diabetic cardiomyopathy 33.56 11.03 10 378272 28 110210989
Sleep apnoea syndrome 33.56 11.03 54 378228 40393 110170624
Central nervous system abscess 33.56 11.03 11 378271 46 110210971
Nephrocalcinosis 33.50 11.03 36 378246 1778 110209239
Balamuthia infection 33.43 11.03 13 378269 97 110210920
Acid fast bacilli infection 33.39 11.03 16 378266 208 110210809
Blood immunoglobulin M decreased 33.37 11.03 38 378244 2003 110209014
Cardiac valve vegetation 33.33 11.03 28 378254 1012 110210005
Therapy non-responder 33.29 11.03 738 377544 156569 110054448
Dysarthria 33.28 11.03 161 378121 83960 110127057
Device breakage 33.24 11.03 4 378278 13765 110197252
Incision site pain 33.18 11.03 47 378235 3088 110207929
Acinetobacter sepsis 33.17 11.03 14 378268 132 110210885
Peripheral coldness 33.15 11.03 11 378271 18529 110192488
Urinary incontinence 33.15 11.03 73 378209 48514 110162503
Metastatic carcinoma of the bladder 33.15 11.03 17 378265 258 110210759
Viral test positive 33.12 11.03 26 378256 852 110210165
Acute hepatic failure 33.06 11.03 226 378056 36242 110174775
Upper limb fracture 33.04 11.03 15 378267 20873 110190144
Pollakiuria 33.04 11.03 63 378219 44132 110166885
Pancreas transplant 33.00 11.03 11 378271 49 110210968
Cerebral ventricle collapse 32.96 11.03 15 378267 172 110210845
Renal amyloidosis 32.82 11.03 18 378264 315 110210702
Crystal nephropathy 32.82 11.03 36 378246 1820 110209197
Vanishing bile duct syndrome 32.80 11.03 47 378235 3121 110207896
Acute myocardial infarction 32.76 11.03 161 378121 83616 110127401
Uraemic encephalopathy 32.71 11.03 25 378257 787 110210230
Urinary retention 32.69 11.03 125 378157 69558 110141459
Depressed level of consciousness 32.68 11.03 237 378045 112041 110098976
Transitional cell carcinoma metastatic 32.62 11.03 14 378268 138 110210879
Accidental exposure to product 32.61 11.03 77 378205 49931 110161086
Septic pulmonary embolism 32.52 11.03 18 378264 321 110210696
Blood calcium decreased 32.51 11.03 45 378237 35800 110175217
Capnocytophaga infection 32.44 11.03 15 378267 179 110210838
Infected neoplasm 32.41 11.03 22 378260 573 110210444
Chronic papillomatous dermatitis 32.40 11.03 12 378270 77 110210940
Herpes zoster 32.37 11.03 536 377746 107843 110103174
Distributive shock 32.36 11.03 66 378216 5838 110205179
Bone disorder 32.32 11.03 16 378266 21176 110189841
Leukaemia in remission 32.31 11.03 9 378273 18 110210999
Transmission of an infectious agent via transplant 32.31 11.03 9 378273 18 110210999
Skin plaque 32.27 11.03 106 378176 12539 110198478
Colon injury 32.22 11.03 19 378263 384 110210633
Hypertensive emergency 32.21 11.03 48 378234 3303 110207714
Acute promyelocytic leukaemia 32.19 11.03 36 378246 1860 110209157
Abdominal wall haemorrhage 32.14 11.03 24 378258 729 110210288
Periorbital cellulitis 32.14 11.03 28 378254 1064 110209953
Arteriovenous fistula thrombosis 32.14 11.03 22 378260 581 110210436
Hepatic vein stenosis 32.14 11.03 11 378271 54 110210963
Blood glucose decreased 32.14 11.03 32 378250 29456 110181561
Retroperitoneal abscess 32.04 11.03 22 378260 584 110210433
Cutaneous sporotrichosis 32.01 11.03 12 378270 80 110210937
Sebaceous hyperplasia 32.01 11.03 12 378270 80 110210937
Radiculopathy 32.00 11.03 13 378269 19323 110191694
Cerebral microhaemorrhage 31.99 11.03 20 378262 451 110210566
Scleroderma renal crisis 31.98 11.03 26 378256 897 110210120
Product administered to patient of inappropriate age 31.89 11.03 79 378203 7957 110203060
Cytomegalovirus myocarditis 31.88 11.03 12 378270 81 110210936
Bacterial colitis 31.78 11.03 16 378266 233 110210784
Gastric perforation 31.77 11.03 59 378223 4870 110206147
Treatment failure 31.75 11.03 714 377568 276520 109934497
Glycosuria 31.71 11.03 42 378240 2588 110208429
Red blood cell schistocytes present 31.64 11.03 24 378258 747 110210270
Tonsil cancer 31.60 11.03 30 378252 1276 110209741
Sinusitis aspergillus 31.59 11.03 17 378265 286 110210731
Roseolovirus test positive 31.59 11.03 17 378265 286 110210731
Nephrectomy 31.59 11.03 42 378240 2598 110208419
Idiopathic intracranial hypertension 31.58 11.03 52 378230 3900 110207117
Haemorrhage intracranial 31.50 11.03 188 378094 28781 110182236
Full blood count decreased 31.49 11.03 38 378244 32061 110178956
Skin infection 31.16 11.03 156 378126 22353 110188664
Gastric haemorrhage 31.10 11.03 8 378274 15907 110195110
Pneumonia adenoviral 30.96 11.03 22 378260 618 110210399
Post procedural complication 30.93 11.03 176 378106 26482 110184535
Unresponsive to stimuli 30.86 11.03 113 378169 63677 110147340
Myocarditis infectious 30.85 11.03 13 378269 122 110210895
Hepatitis 30.82 11.03 181 378101 89873 110121144
Arterial disorder 30.80 11.03 38 378244 2181 110208836
Eye abscess 30.78 11.03 18 378264 358 110210659
Angina unstable 30.72 11.03 9 378273 16423 110194594
Angiopathy 30.70 11.03 82 378200 8648 110202369
Acquired macroglossia 30.67 11.03 16 378266 252 110210765
Microsporum infection 30.66 11.03 10 378272 41 110210976
Peripheral T-cell lymphoma unspecified 30.66 11.03 25 378257 866 110210151
Haemoperitoneum 30.44 11.03 61 378221 5327 110205690
Tongue disorder 30.32 11.03 6 378276 14292 110196725
Fluorosis 30.32 11.03 15 378267 210 110210807
Increased appetite 30.30 11.03 7 378275 14970 110196047
Hyperparathyroidism 30.26 11.03 50 378232 3760 110207257
Gingivitis ulcerative 30.18 11.03 20 378262 500 110210517
Lung infiltration 30.17 11.03 165 378117 24463 110186554
Surgical procedure repeated 30.15 11.03 23 378259 722 110210295
Second primary malignancy 30.14 11.03 12 378270 18056 110192961
Febrile bone marrow aplasia 30.13 11.03 11 378271 17454 110193563
Renal cyst infection 30.12 11.03 16 378266 262 110210755
Immune-mediated adverse reaction 30.11 11.03 33 378249 1667 110209350
Herpes simplex viraemia 30.08 11.03 22 378260 647 110210370
Oxalosis 30.04 11.03 13 378269 131 110210886
Oesophageal squamous cell carcinoma 30.04 11.03 20 378262 504 110210513
Musculoskeletal discomfort 29.98 11.03 22 378260 23516 110187501
Pneumonia legionella 29.93 11.03 48 378234 3521 110207496
Tuberculosis of genitourinary system 29.93 11.03 12 378270 98 110210919
Encephalitis protozoal 29.92 11.03 10 378272 45 110210972
IIIrd nerve paralysis 29.89 11.03 30 378252 1367 110209650
Sinus bradycardia 29.89 11.03 34 378248 29449 110181568
Erosive duodenitis 29.83 11.03 38 378244 2253 110208764
Coinfection 29.79 11.03 13 378269 134 110210883
Cyclosporidium infection 29.78 11.03 8 378274 13 110211004
Abdominal wound dehiscence 29.76 11.03 17 378265 323 110210694
Cell death 29.70 11.03 63 378219 5728 110205289
Purtscher retinopathy 29.70 11.03 15 378267 220 110210797
Lymphadenopathy mediastinal 29.69 11.03 61 378221 5423 110205594
Malignant ascites 29.66 11.03 30 378252 1380 110209637
Acanthamoeba keratitis 29.62 11.03 7 378275 4 110211013
Burkholderia cepacia complex sepsis 29.62 11.03 7 378275 4 110211013
Tuberculosis of central nervous system 29.59 11.03 20 378262 517 110210500
Musculoskeletal chest pain 29.53 11.03 33 378249 28814 110182203
Adenovirus test positive 29.51 11.03 12 378270 102 110210915
Periodontitis 29.47 11.03 59 378223 5149 110205868
Acanthoma 29.40 11.03 10 378272 48 110210969
Spinal disorder 29.34 11.03 3 378279 11725 110199292
Propionibacterium infection 29.18 11.03 16 378266 280 110210737
Gastric disorder 29.15 11.03 43 378239 33314 110177703
Pelvic deformity 29.13 11.03 11 378271 75 110210942
Biliary obstruction 29.13 11.03 61 378221 5497 110205520
Renal atrophy 29.12 11.03 38 378244 2308 110208709
Upper-airway cough syndrome 29.08 11.03 9 378273 15848 110195169
Soft tissue infection 29.07 11.03 58 378224 5049 110205968
Protein urine present 29.07 11.03 96 378186 11388 110199629
Beta-N-acetyl-D-glucosaminidase increased 29.07 11.03 10 378272 50 110210967
Aspergillus test positive 29.06 11.03 26 378256 1024 110209993
Salmonellosis 29.04 11.03 37 378245 2194 110208823
Middle insomnia 29.04 11.03 17 378265 20485 110190532
Parasitic gastroenteritis 28.99 11.03 15 378267 232 110210785
Protothecosis 28.93 11.03 20 378262 537 110210480
Giant cell myocarditis 28.91 11.03 10 378272 51 110210966
Obstructive nephropathy 28.89 11.03 11 378271 77 110210940
Post infection glomerulonephritis 28.88 11.03 13 378269 145 110210872
Paraspinal abscess 28.71 11.03 18 378264 408 110210609
Intervertebral disc degeneration 28.59 11.03 13 378269 18072 110192945
Eosinophilic colitis 28.58 11.03 21 378261 622 110210395
Liver function test abnormal 28.54 11.03 361 377921 68589 110142428
Stem cell transplant 28.54 11.03 53 378229 4374 110206643
Chromaturia 28.54 11.03 35 378247 29325 110181692
Pneumocephalus 28.53 11.03 19 378263 479 110210538
Acidosis hyperchloraemic 28.46 11.03 31 378251 1555 110209462
Eczema 28.45 11.03 375 377907 71918 110139099
Drug trough level 28.44 11.03 10 378272 54 110210963
Injection site rash 28.41 11.03 23 378259 23396 110187621
Cryoglobulinaemia 28.35 11.03 28 378254 1251 110209766
Cyanosis 28.34 11.03 36 378246 29705 110181312
Hyperthyroidism 28.32 11.03 35 378247 29226 110181791
Acute allograft nephropathy 28.28 11.03 10 378272 55 110210962
Mesangioproliferative glomerulonephritis 28.27 11.03 15 378267 245 110210772
Rotator cuff syndrome 28.27 11.03 11 378271 16783 110194234
Burkitt's lymphoma 28.26 11.03 12 378270 115 110210902
Tonsillar hypertrophy 28.22 11.03 34 378248 1904 110209113
Adrenal mass 28.20 11.03 31 378251 1571 110209446
Faecaloma 28.18 11.03 8 378274 14900 110196117
Petechiae 28.16 11.03 23 378259 23294 110187723
Hepatic infection 27.99 11.03 28 378254 1271 110209746
Gastrointestinal tract adenoma 27.98 11.03 20 378262 567 110210450
Orthobunyavirus test positive 27.94 11.03 7 378275 7 110211010
Lacrimation increased 27.93 11.03 39 378243 30911 110180106
Metapneumovirus pneumonia 27.92 11.03 14 378268 202 110210815
Reperfusion injury 27.92 11.03 14 378268 202 110210815
Splenic infection viral 27.77 11.03 9 378273 36 110210981
Rotavirus infection 27.75 11.03 24 378258 903 110210114
Cholangitis infective 27.74 11.03 23 378259 816 110210201
Small intestinal perforation 27.73 11.03 52 378230 4324 110206693
Acidosis 27.64 11.03 151 378131 22380 110188637
Facial pain 27.60 11.03 9 378273 15330 110195687
Cryptococcal meningoencephalitis 27.60 11.03 17 378265 373 110210644
Agranulocytosis 27.58 11.03 328 377954 61432 110149585
Biphasic mesothelioma 27.56 11.03 10 378272 60 110210957
Myasthenia gravis 27.53 11.03 20 378262 21491 110189526
Intestinal perforation 27.49 11.03 143 378139 20801 110190216
Perihepatic abscess 27.47 11.03 13 378269 164 110210853
Anal squamous cell carcinoma 27.43 11.03 23 378259 829 110210188
Moyamoya disease 27.38 11.03 12 378270 125 110210892
Pancreatic pseudocyst 27.33 11.03 31 378251 1627 110209390
Temperature intolerance 27.28 11.03 7 378275 13943 110197074
Cardiac tamponade 27.28 11.03 93 378189 11214 110199803
Paternal exposure during pregnancy 27.27 11.03 14 378268 213 110210804
Pharyngeal oedema 27.26 11.03 11 378271 16417 110194600
Congenital cystic kidney disease 27.24 11.03 17 378265 382 110210635
Hidradenocarcinoma 27.22 11.03 8 378274 21 110210996
Restrictive allograft syndrome 27.22 11.03 8 378274 21 110210996
Complications of intestinal transplant 27.22 11.03 8 378274 21 110210996
Rash erythematous 27.20 11.03 166 378116 81666 110129351
Abnormal behaviour 27.18 11.03 58 378224 38981 110172036
Failure to thrive 27.11 11.03 105 378177 13469 110197548
Status epilepticus 27.06 11.03 193 378089 31378 110179639
Influenza 27.02 11.03 411 377871 168690 110042327
Herpes simplex meningomyelitis 27.01 11.03 7 378275 9 110211008
Blood phosphorus increased 27.01 11.03 11 378271 16329 110194688
Hypercalcaemia 26.99 11.03 261 378021 46396 110164621
CEC syndrome 26.95 11.03 8 378274 22 110210995
Chylothorax 26.92 11.03 26 378256 1130 110209887
Alanine aminotransferase increased 26.91 11.03 454 377828 183319 110027698
Hepatic haematoma 26.91 11.03 24 378258 941 110210076
Joint destruction 26.86 11.03 3 378279 10940 110200077
Arteriovenous fistula occlusion 26.85 11.03 19 378263 530 110210487
Tick-borne viral encephalitis 26.79 11.03 13 378269 174 110210843
Haemophilus infection 26.76 11.03 40 378242 2760 110208257
Hypertension 26.74 11.03 1449 376833 508635 109702382
Blood parathyroid hormone decreased 26.72 11.03 6 378276 13083 110197934
Genital herpes 26.68 11.03 38 378244 2509 110208508
Varicella zoster pneumonia 26.67 11.03 17 378265 397 110210620
Lymphoma 26.66 11.03 138 378144 20033 110190984
Orbital infection 26.66 11.03 13 378269 176 110210841
Fear 26.64 11.03 24 378258 23169 110187848
Continuous haemodiafiltration 26.64 11.03 33 378249 1902 110209115
Necrosis of artery 26.59 11.03 7 378275 10 110211007
Epstein-Barr virus test negative 26.59 11.03 7 378275 10 110211007
Renal tubular dysfunction 26.56 11.03 23 378259 867 110210150
Bordetella infection 26.53 11.03 14 378268 226 110210791
Enterobacter bacteraemia 26.52 11.03 29 378253 1461 110209556
Intrauterine infection 26.51 11.03 10 378272 68 110210949
Diabetic nephropathy 26.48 11.03 45 378237 3463 110207554
Rhabdoid tumour 26.44 11.03 8 378274 24 110210993
Adjustment disorder 26.40 11.03 3 378279 10792 110200225
Wound infection fungal 26.37 11.03 14 378268 229 110210788
Renal ischaemia 26.34 11.03 36 378246 2287 110208730
Gallbladder disorder 26.34 11.03 20 378262 21009 110190008
Procedural pain 26.32 11.03 51 378231 35514 110175503
Cytomegalovirus mucocutaneous ulcer 26.26 11.03 12 378270 139 110210878
Sneezing 26.26 11.03 43 378239 31941 110179076
Neuropsychiatric lupus 26.21 11.03 14 378268 232 110210785
Restrictive pulmonary disease 26.20 11.03 43 378239 3216 110207801
Vitritis infective 26.16 11.03 9 378273 45 110210972
Duodenitis 26.13 11.03 80 378202 9116 110201901
Drug tolerance 26.09 11.03 12 378270 16573 110194444
Rhinocerebral mucormycosis 26.09 11.03 29 378253 1488 110209529
Upper gastrointestinal haemorrhage 26.08 11.03 86 378196 50010 110161007
Acute disseminated encephalomyelitis 26.08 11.03 17 378265 413 110210604
Hyperplasia 26.08 11.03 29 378253 1489 110209528
Multimorbidity 26.04 11.03 29 378253 1491 110209526
Unmasking of previously unidentified disease 26.03 11.03 40 378242 2828 110208189
Hypouricaemia 25.97 11.03 19 378263 559 110210458
Removal of renal transplant 25.97 11.03 8 378274 26 110210991
Pulmonary air leakage 25.94 11.03 15 378267 292 110210725
Ankle fracture 25.93 11.03 18 378264 19801 110191216
Hypopnoea 25.83 11.03 4 378278 11376 110199641
Ejection fraction decreased 25.82 11.03 64 378218 40816 110170201
Hantaviral infection 25.82 11.03 7 378275 12 110211005
Oral hairy leukoplakia 25.82 11.03 7 378275 12 110211005
Pleomorphism 25.82 11.03 7 378275 12 110211005
Tonsillitis 25.77 11.03 74 378208 8139 110202878
Blood immunoglobulin A decreased 25.73 11.03 35 378247 2213 110208804
Cerebral infarction 25.71 11.03 281 378001 51557 110159460
Eye swelling 25.69 11.03 46 378236 33002 110178015
Pleural adhesion 25.67 11.03 15 378267 298 110210719
Blood creatinine abnormal 25.61 11.03 60 378222 5832 110205185
Dementia 25.61 11.03 43 378239 31630 110179387
Peripheral artery aneurysm 25.60 11.03 18 378264 497 110210520
Granuloma skin 25.53 11.03 4 378278 11279 110199738
Blood calcium increased 25.50 11.03 15 378267 18025 110192992
Ageusia 25.49 11.03 18 378264 19627 110191390
Metastasis 25.47 11.03 74 378208 8193 110202824
Tendonitis 25.45 11.03 31 378251 26052 110184965
Herpes simplex meningoencephalitis 25.44 11.03 10 378272 77 110210940
Apoptotic colonopathy 25.42 11.03 13 378269 196 110210821
Myelitis transverse 25.42 11.03 36 378246 2365 110208652
Movement disorder 25.41 11.03 54 378228 36350 110174667
Bile duct necrosis 25.33 11.03 10 378272 78 110210939
Lung adenocarcinoma 25.32 11.03 81 378201 9450 110201567
Prostate cancer 25.32 11.03 57 378225 37584 110173433
Gastrinoma 25.23 11.03 9 378273 51 110210966
Moraxella infection 25.23 11.03 21 378261 749 110210268
Renal cell carcinoma stage I 25.22 11.03 10 378272 79 110210938
Myoclonic dystonia 25.22 11.03 10 378272 79 110210938
Stomatococcal infection 25.16 11.03 16 378266 372 110210645
Blood lactate dehydrogenase increased 25.15 11.03 247 378035 44087 110166930
Fibromatosis colli of infancy 25.13 11.03 7 378275 14 110211003
Acquired plagiocephaly 25.13 11.03 7 378275 14 110211003
Parametritis 25.13 11.03 7 378275 14 110211003
Cow pox 25.09 11.03 8 378274 30 110210987
Maternal exposure timing unspecified 25.04 11.03 21 378261 20992 110190025
Gastrointestinal necrosis 25.02 11.03 64 378218 6576 110204441
Gastrointestinal ulcer 25.00 11.03 49 378233 4211 110206806
Mycoplasma test positive 24.98 11.03 14 378268 256 110210761
Emotional disorder 24.95 11.03 12 378270 16148 110194869
Hepatic cyst infection 24.91 11.03 13 378269 205 110210812
Osteonecrosis 24.83 11.03 199 378083 33542 110177475
Trichophytic granuloma 24.80 11.03 9 378273 54 110210963
Brucellosis 24.77 11.03 12 378270 160 110210857
Leukaemia recurrent 24.75 11.03 41 378241 3090 110207927
Pyogenic granuloma 24.74 11.03 18 378264 525 110210492
Interstitial lung disease 24.71 11.03 638 377644 138696 110072321
Phospholipidosis 24.68 11.03 15 378267 321 110210696
Neutrophil morphology abnormal 24.66 11.03 11 378271 120 110210897
Electrocardiogram QRS complex prolonged 24.59 11.03 7 378275 13014 110198003
Disseminated Bacillus Calmette-Guerin infection 24.52 11.03 15 378267 325 110210692
Escherichia test positive 24.49 11.03 44 378238 3540 110207477
Conjunctival melanoma 24.47 11.03 6 378276 5 110211012
Hepatitis infectious mononucleosis 24.46 11.03 13 378269 213 110210804
Seasonal allergy 24.39 11.03 19 378263 19703 110191314
Pulmonary sepsis 24.32 11.03 55 378227 5223 110205794
Infection protozoal 24.26 11.03 9 378273 58 110210959
Abscess limb 24.22 11.03 74 378208 8423 110202594
Protein-losing gastroenteropathy 24.22 11.03 22 378260 884 110210133
White blood cell count increased 24.22 11.03 213 378069 96629 110114388
Nocturia 24.19 11.03 14 378268 16976 110194041
SARS-CoV-2 antibody test positive 24.18 11.03 16 378266 399 110210618
Pseudomonal sepsis 24.14 11.03 77 378205 8969 110202048
Mastitis bacterial 24.13 11.03 9 378273 59 110210958
Gastrointestinal ulcer perforation 24.13 11.03 9 378273 59 110210958
Anastomotic haemorrhage 24.12 11.03 15 378267 335 110210682
Blood 1,25-dihydroxycholecalciferol increased 24.10 11.03 10 378272 90 110210927
Vena cava injury 24.04 11.03 15 378267 337 110210680
Graft haemorrhage 24 11.03 10 378272 91 110210926
Acute myeloid leukaemia 23.95 11.03 217 378065 37893 110173124
Squamous cell carcinoma of the vulva 23.95 11.03 6 378276 6 110211011
Conjunctival neoplasm 23.95 11.03 6 378276 6 110211011
Latent autoimmune diabetes in adults 23.94 11.03 12 378270 173 110210844
Face oedema 23.91 11.03 49 378233 33420 110177597
Gastrointestinal injury 23.89 11.03 31 378251 1872 110209145
Iron deficiency 23.88 11.03 17 378265 18459 110192558
Pneumonia escherichia 23.86 11.03 25 378257 1199 110209818
Bone marrow oedema 23.82 11.03 33 378249 2123 110208894
Nephrolithiasis 23.78 11.03 131 378151 66081 110144936
Metastases to retroperitoneum 23.73 11.03 16 378266 412 110210605
Eosinophilic granulomatosis with polyangiitis 23.70 11.03 4 378278 10682 110200335
Meningitis staphylococcal 23.68 11.03 13 378269 228 110210789
Gastric ulcer haemorrhage, obstructive 23.65 11.03 7 378275 19 110210998
Metastases to skin 23.64 11.03 34 378248 2265 110208752
Central nervous system immune reconstitution inflammatory response 23.63 11.03 9 378273 63 110210954
Drug dose omission by device 23.63 11.03 10 378272 14506 110196511
Serositis 23.62 11.03 28 378254 1541 110209476
Beta haemolytic streptococcal infection 23.61 11.03 39 378243 2932 110208085
Renal infarct 23.61 11.03 42 378240 3353 110207664
Herpes simplex encephalitis 23.54 11.03 21 378261 824 110210193
Soft tissue sarcoma 23.53 11.03 14 378268 288 110210729
Necrotising fasciitis 23.43 11.03 68 378214 7523 110203494
Steroid withdrawal syndrome 23.42 11.03 22 378260 923 110210094
Pneumococcal infection 23.42 11.03 30 378252 1789 110209228
Rash maculo-papular 23.41 11.03 153 378129 74069 110136948
Optic pathway injury 23.41 11.03 5 378277 0 110211017
Coma 23.37 11.03 274 378008 117595 110093422
Thrombosis 23.36 11.03 248 378034 108414 110102603
Haemorrhagic pneumonia 23.29 11.03 12 378270 184 110210833
Skin angiosarcoma 23.14 11.03 7 378275 21 110210996
Granulicatella bacteraemia 23.14 11.03 7 378275 21 110210996
Prostatic specific antigen increased 23.12 11.03 7 378275 12504 110198513
Bacterial translocation 23.08 11.03 27 378255 1465 110209552
Vascular anastomotic haemorrhage 23.06 11.03 14 378268 299 110210718
Breast cancer female 23 11.03 7 378275 12461 110198556
Bacillus infection 22.98 11.03 28 378254 1586 110209431
Maternal exposure during pregnancy 22.90 11.03 680 377602 254203 109956814
Pelvic pain 22.89 11.03 13 378269 15929 110195088
Monocytosis 22.88 11.03 29 378253 1711 110209306
Pneumonia mycoplasmal 22.86 11.03 29 378253 1712 110209305
Viral skin infection 22.84 11.03 12 378270 192 110210825
Biliary ischaemia 22.83 11.03 10 378272 104 110210913
Pre-engraftment immune reaction 22.71 11.03 16 378266 443 110210574
Neutrophilic dermatosis 22.69 11.03 20 378262 772 110210245
Hyperaesthesia 22.64 11.03 11 378271 14716 110196301
Extrapyramidal disorder 22.60 11.03 40 378242 28827 110182190
Osteomyelitis chronic 22.58 11.03 20 378262 777 110210240
Viral mutation identified 22.58 11.03 48 378234 4371 110206646
Hirsutism 22.58 11.03 29 378253 1734 110209283
Spindle cell sarcoma 22.57 11.03 13 378269 251 110210766
Malassezia infection 22.50 11.03 9 378273 73 110210944
Encephalitis fungal 22.48 11.03 13 378269 253 110210764
Symptom masked 22.45 11.03 30 378252 1865 110209152
Staphylococcal scalded skin syndrome 22.44 11.03 17 378265 528 110210489
Multiple allergies 22.42 11.03 7 378275 12256 110198761
Skin discolouration 22.35 11.03 89 378193 48957 110162060
Type 1 diabetes mellitus 22.34 11.03 75 378207 8972 110202045
Mucosal hypertrophy 22.26 11.03 10 378272 111 110210906
Temperature regulation disorder 22.26 11.03 8 378274 12818 110198199
Impaired quality of life 22.26 11.03 43 378239 29974 110181043
Intestinal ulcer 22.24 11.03 34 378248 2393 110208624
Thyroid tuberculosis 22.22 11.03 7 378275 25 110210992
Lupus enteritis 22.18 11.03 9 378273 76 110210941
Immune-mediated enterocolitis 22.18 11.03 4 378278 10181 110200836
Systemic inflammatory response syndrome 22.18 11.03 96 378186 12947 110198070
Parvovirus B19 test positive 22.17 11.03 11 378271 155 110210862
Tooth infection 22.11 11.03 26 378256 22190 110188827
Musculoskeletal disorder 22.05 11.03 27 378255 22637 110188380
Arterial fibrosis 22.00 11.03 7 378275 26 110210991
Platelet count increased 22.00 11.03 35 378247 26299 110184718
Cardiac septal hypertrophy 21.98 11.03 15 378267 394 110210623
Retroperitoneal haematoma 21.98 11.03 58 378224 6073 110204944
Electrocardiogram abnormal 21.93 11.03 19 378263 18690 110192327
Diarrhoea infectious 21.90 11.03 30 378252 1910 110209107
Arthritis bacterial 21.86 11.03 84 378198 10736 110200281
Vitamin B12 deficiency 21.79 11.03 4 378278 10051 110200966
Schistosomiasis 21.77 11.03 8 378274 50 110210967
Coagulation test abnormal 21.76 11.03 27 378255 1559 110209458
Lung adenocarcinoma stage IV 21.74 11.03 17 378265 554 110210463
Bronchostenosis 21.66 11.03 21 378261 917 110210100
Herpes oesophagitis 21.66 11.03 15 378267 404 110210613
Pericardial cyst 21.64 11.03 8 378274 51 110210966
Myocarditis mycotic 21.64 11.03 8 378274 51 110210966
Placenta accreta 21.63 11.03 12 378270 215 110210802
Eschar 21.59 11.03 26 378256 1455 110209562
Enterococcus test positive 21.59 11.03 37 378245 2867 110208150
Respiratory tract inflammation 21.59 11.03 22 378260 1021 110209996
Cyst 21.56 11.03 15 378267 16481 110194536
Extra-axial haemorrhage 21.54 11.03 6 378276 12 110211005
Chest wall abscess 21.52 11.03 14 378268 339 110210678
Aspergillosis oral 21.51 11.03 8 378274 52 110210965
Fluoride increased 21.40 11.03 9 378273 84 110210933
Atrial tachycardia 21.35 11.03 3 378279 9175 110201842
Pulmonary arterial hypertension 21.35 11.03 50 378232 32518 110178499
Hypervolaemia 21.35 11.03 261 378021 49199 110161818
Arteriosclerosis coronary artery 21.35 11.03 33 378249 25085 110185932
Ear discomfort 21.33 11.03 6 378276 11243 110199774
Adenocarcinoma 21.31 11.03 46 378236 4234 110206783
Intraductal papillary mucinous neoplasm 21.30 11.03 20 378262 839 110210178
Hepatorenal syndrome 21.29 11.03 48 378234 4549 110206468
Rhesus antigen positive 21.29 11.03 10 378272 124 110210893
Renal lymphocele 21.29 11.03 10 378272 124 110210893
Adult T-cell lymphoma/leukaemia recurrent 21.25 11.03 8 378274 54 110210963
Cardiac failure 21.25 11.03 484 377798 187142 110023875
Corneal graft rejection 21.21 11.03 10 378272 125 110210892
Hallucination, auditory 21.19 11.03 36 378246 26361 110184656
Heart transplant 21.19 11.03 27 378255 1601 110209416
Feeling jittery 21.15 11.03 12 378270 14710 110196307
Glomerular vascular disorder 21.15 11.03 12 378270 225 110210792
Cell-mediated immune deficiency 21.15 11.03 12 378270 225 110210792
Breast cancer metastatic 21.13 11.03 6 378276 11175 110199842
Peptostreptococcus infection 21.10 11.03 11 378271 173 110210844
Keratouveitis 21.03 11.03 7 378275 31 110210986
Acute lymphocytic leukaemia recurrent 21.00 11.03 55 378227 5732 110205285
Dyschromatopsia 21.00 11.03 24 378258 1270 110209747
Mental impairment 20.96 11.03 28 378254 22611 110188406
Arterial thrombosis 20.94 11.03 38 378244 3081 110207936
Cystitis 20.89 11.03 136 378146 65900 110145117
NPM1 gene mutation 20.87 11.03 10 378272 130 110210887
Hemianopia homonymous 20.85 11.03 26 378256 1509 110209508
Metastases to nervous system 20.80 11.03 13 378269 293 110210724
Portal vein occlusion 20.77 11.03 9 378273 91 110210926
Blood urea increased 20.77 11.03 283 377999 54674 110156343
Renal salt-wasting syndrome 20.73 11.03 20 378262 868 110210149
Upper respiratory tract infection 20.70 11.03 320 377962 131008 110080009
Immunodeficiency 20.68 11.03 66 378216 38772 110172245
Arterioenteric fistula 20.68 11.03 7 378275 33 110210984
Ankylosing spondylitis 20.66 11.03 14 378268 15598 110195419
Intra-abdominal haemorrhage 20.66 11.03 52 378230 5290 110205727
Upper respiratory tract inflammation 20.65 11.03 46 378236 4325 110206692
Urinary tract injury 20.62 11.03 6 378276 15 110211002
Multiple fractures 20.62 11.03 3 378279 8937 110202080
Incontinence 20.60 11.03 16 378266 16619 110194398
Necrotising herpetic retinopathy 20.50 11.03 11 378271 184 110210833
Product prescribing error 20.44 11.03 98 378184 51233 110159784
Incisional hernia 20.42 11.03 35 378247 2712 110208305
Foot fracture 20.36 11.03 35 378247 25511 110185506
Capillary leak syndrome 20.28 11.03 49 378233 4859 110206158
Foetal growth restriction 20.27 11.03 37 378245 3013 110208004
Squamous cell carcinoma of the cervix 20.26 11.03 13 378269 307 110210710
Gastroenteritis eosinophilic 20.21 11.03 14 378268 377 110210640
Anhedonia 20.20 11.03 14 378268 15414 110195603
Visual field defect 20.19 11.03 78 378204 9994 110201023
Pancreatic abscess 20.19 11.03 11 378271 190 110210827
Arteritis 20.14 11.03 22 378260 1107 110209910
Sinus tachycardia 20.11 11.03 81 378201 44412 110166605
Diabetic macroangiopathy 20.09 11.03 10 378272 142 110210875
Plasmapheresis 20.08 11.03 19 378263 805 110210212
Synovial cyst 20.06 11.03 7 378275 11423 110199594
Surgery 20.05 11.03 73 378209 41210 110169807
Meningoencephalitis bacterial 20.05 11.03 15 378267 457 110210560
Dermatitis allergic 19.98 11.03 27 378255 21697 110189320
Frustration tolerance decreased 19.97 11.03 3 378279 8728 110202289
Lip squamous cell carcinoma 19.97 11.03 13 378269 315 110210702
Epithelioid mesothelioma 19.96 11.03 5 378277 5 110211012
Membranous-like glomerulopathy with masked IgG-kappa deposits 19.96 11.03 5 378277 5 110211012
Injection site induration 19.93 11.03 7 378275 11376 110199641
Arteriovenous fistula 19.92 11.03 25 378257 1460 110209557
Lactic acidosis 19.88 11.03 212 378070 92599 110118418
Abscess soft tissue 19.86 11.03 12 378270 254 110210763
Transaminases increased 19.86 11.03 316 377966 63074 110147943
Muscle tightness 19.86 11.03 13 378269 14749 110196268
Renal artery arteriosclerosis 19.78 11.03 8 378274 67 110210950
Hernial eventration 19.78 11.03 8 378274 67 110210950
Hyperparathyroidism tertiary 19.78 11.03 8 378274 67 110210950
Haptoglobin decreased 19.77 11.03 27 378255 1714 110209303
Oral discomfort 19.72 11.03 7 378275 11304 110199713
Rabies 19.72 11.03 7 378275 39 110210978
Angioimmunoblastic T-cell lymphoma 19.71 11.03 17 378265 637 110210380
Drug level abnormal 19.70 11.03 16 378266 551 110210466
Hypomagnesaemia 19.69 11.03 303 377979 60067 110150950
Anal ulcer 19.67 11.03 28 378254 1848 110209169
Gingival pain 19.66 11.03 15 378267 15721 110195296
Anosmia 19.66 11.03 9 378273 12463 110198554
Infective thrombosis 19.64 11.03 9 378273 105 110210912
Lymphorrhoea 19.64 11.03 11 378271 201 110210816
Hepatic echinococciasis 19.57 11.03 8 378274 69 110210948
Osteomyelitis bacterial 19.56 11.03 16 378266 557 110210460
Premature baby 19.55 11.03 48 378234 4807 110206210
Sweat gland tumour 19.53 11.03 16 378266 558 110210459
Tooth extraction 19.52 11.03 10 378272 12981 110198036
Lymphangiectasia 19.49 11.03 9 378273 107 110210910
Biliary tract infection fungal 19.49 11.03 5 378277 6 110211011
Bacterial endophthalmitis 19.48 11.03 13 378269 329 110210688
Cardiac autonomic neuropathy 19.47 11.03 8 378274 70 110210947
VIth nerve paralysis 19.46 11.03 27 378255 1740 110209277
Fibrosis 19.45 11.03 64 378218 7578 110203439
Eructation 19.43 11.03 12 378270 14045 110196972
Post herpetic neuralgia 19.41 11.03 38 378244 3263 110207754
Fat necrosis 19.38 11.03 20 378262 942 110210075
Otitis media 19.38 11.03 63 378219 7413 110203604
Pancreatic leak 19.36 11.03 6 378276 20 110210997
Increased tendency to bruise 19.30 11.03 8 378274 11750 110199267
Product administration error 19.30 11.03 64 378218 37153 110173864
Hepatic infection bacterial 19.29 11.03 7 378275 42 110210975
Metabolic encephalopathy 19.27 11.03 82 378200 10978 110200039
Enterocolitis haemorrhagic 19.13 11.03 33 378249 2571 110208446
Hepatic infarction 19.06 11.03 20 378262 961 110210056
Urogenital infection bacterial 19.06 11.03 9 378273 113 110210904
High grade B-cell lymphoma Burkitt-like lymphoma stage IV 19.05 11.03 5 378277 7 110211010
Hypoaesthesia oral 19.05 11.03 18 378264 16984 110194033
Leishmaniasis 19.04 11.03 15 378267 494 110210523
Nodular melanoma 19.02 11.03 12 378270 275 110210742
Urethral polyp 18.99 11.03 8 378274 75 110210942
Infective scleritis 18.99 11.03 9 378273 114 110210903
Spinal fracture 18.98 11.03 30 378252 22603 110188414
Thirst 18.95 11.03 28 378254 21679 110189338
Pseudallescheria infection 18.92 11.03 6 378276 22 110210995
Urine protein/creatinine ratio increased 18.78 11.03 25 378257 1548 110209469
Spinal operation 18.78 11.03 7 378275 10965 110200052
Multiple organ transplant rejection 18.73 11.03 4 378278 0 110211017
Mesenteric fibrosis 18.73 11.03 4 378278 0 110211017
Petrositis 18.73 11.03 4 378278 0 110211017
Vasoconstriction 18.72 11.03 21 378261 1089 110209928
Viral sepsis 18.71 11.03 11 378271 221 110210796
Pancreatic pseudocyst haemorrhage 18.66 11.03 5 378277 8 110211009
Seroconversion test negative 18.66 11.03 5 378277 8 110211009
Bullous haemorrhagic dermatosis 18.64 11.03 13 378269 354 110210663
Arthropod bite 18.63 11.03 5 378277 9666 110201351
Splenic neoplasm malignancy unspecified 18.63 11.03 7 378275 47 110210970
Optic perineuritis 18.63 11.03 7 378275 47 110210970
Retinal ischaemia 18.62 11.03 20 378262 987 110210030
Cachexia 18.62 11.03 91 378191 12914 110198103
Viral infection 18.62 11.03 270 378012 52869 110158148
Device related bacteraemia 18.60 11.03 22 378260 1208 110209809
Coagulopathy 18.58 11.03 218 378064 40693 110170324
Wound infection staphylococcal 18.55 11.03 38 378244 3371 110207646
Eosinophil count increased 18.54 11.03 27 378255 21031 110189986
Focal myositis 18.51 11.03 6 378276 24 110210993
Cardiac murmur 18.50 11.03 35 378247 24593 110186424
Epiploic appendagitis 18.49 11.03 10 378272 170 110210847
Cytotoxic oedema 18.48 11.03 14 378268 435 110210582
Asphyxia 18.48 11.03 13 378269 14202 110196815
Stenotrophomonas sepsis 18.45 11.03 11 378271 227 110210790
Ophthalmic herpes simplex 18.41 11.03 19 378263 895 110210122
Milk allergy 18.39 11.03 12 378270 292 110210725
Oesophagitis ulcerative 18.39 11.03 25 378257 1580 110209437
Scrotal cellulitis 18.37 11.03 8 378274 82 110210935
Osteomyelitis acute 18.34 11.03 16 378266 609 110210408
Gastrointestinal stromal tumour 18.34 11.03 29 378253 2102 110208915
Scopulariopsis infection 18.34 11.03 10 378272 173 110210844
T-cell lymphoma stage IV 18.34 11.03 10 378272 173 110210844
Deafness 18.33 11.03 40 378242 26669 110184348
Autoimmune anaemia 18.32 11.03 6 378276 25 110210992
Genital disorder 18.32 11.03 6 378276 25 110210992
Product use issue 18.32 11.03 875 377407 310820 109900197
Renal arteritis 18.29 11.03 5 378277 9 110211008
Toxic leukoencephalopathy 18.24 11.03 25 378257 1592 110209425
Hypokinesia 18.24 11.03 29 378253 21797 110189220
Feeding disorder 18.22 11.03 28 378254 21334 110189683
Perineal cyst 18.20 11.03 11 378271 233 110210784
Perforation bile duct 18.20 11.03 8 378274 84 110210933
No adverse event 18.20 11.03 163 378119 73676 110137341
Erectile dysfunction 18.16 11.03 22 378260 18534 110192483
Dizziness postural 18.16 11.03 14 378268 14595 110196422
Small intestine adenocarcinoma 18.16 11.03 11 378271 234 110210783
Retching 18.15 11.03 31 378251 22651 110188366
Bullous erysipelas 18.13 11.03 6 378276 26 110210991
Staphylococcal skin infection 18.12 11.03 27 378255 1858 110209159
Refractoriness to platelet transfusion 18.04 11.03 11 378271 237 110210780
Capillaritis 18.03 11.03 31 378251 2408 110208609
Product storage error 18.03 11.03 29 378253 21699 110189318
Gastrointestinal pain 18.02 11.03 9 378273 11851 110199166
Oral lichenoid reaction 17.99 11.03 10 378272 180 110210837
Bone marrow granuloma 17.95 11.03 6 378276 27 110210990
Pneumonia acinetobacter 17.84 11.03 13 378269 380 110210637
Metastases to spleen 17.83 11.03 18 378264 826 110210191
Oral allergy syndrome 17.79 11.03 8 378274 89 110210928
Sarcoma metastatic 17.79 11.03 8 378274 89 110210928
Meningitis Escherichia 17.78 11.03 6 378276 28 110210989
Ischaemic cardiomyopathy 17.77 11.03 3 378279 8008 110203009
Extrapulmonary tuberculosis 17.76 11.03 15 378267 546 110210471
Exposure during pregnancy 17.76 11.03 721 377561 166703 110044314
B-lymphocyte count decreased 17.73 11.03 28 378254 2027 110208990
Organ failure 17.71 11.03 46 378236 4771 110206246
Muscle neoplasm 17.69 11.03 7 378275 55 110210962
Hypergammaglobulinaemia 17.67 11.03 19 378263 939 110210078
Vaginal haemorrhage 17.66 11.03 37 378245 25037 110185980
Muscle necrosis 17.64 11.03 26 378256 1771 110209246
Blood albumin increased 17.62 11.03 27 378255 1904 110209113
Spinal cord abscess 17.61 11.03 16 378266 643 110210374
Hypernatraemia 17.61 11.03 21 378261 17812 110193205
Palatal ulcer 17.60 11.03 11 378271 248 110210769
Anal incontinence 17.59 11.03 30 378252 21934 110189083
HIV infection 17.58 11.03 22 378260 1281 110209736
Neurologic neglect syndrome 17.56 11.03 5 378277 9293 110201724
Deep vein thrombosis 17.54 11.03 355 377927 139532 110071485
Hepatic neoplasm 17.49 11.03 40 378242 3827 110207190
Renal adenoma 17.47 11.03 7 378275 57 110210960
Cardiac valve abscess 17.47 11.03 9 378273 138 110210879
Retroperitoneal lymphadenopathy 17.42 11.03 23 378259 1413 110209604
Malignant melanoma 17.34 11.03 108 378174 16783 110194234
Oesophageal tuberculosis 17.33 11.03 5 378277 12 110211005
Meningitis enterococcal 17.32 11.03 10 378272 194 110210823
Cerebral cyst 17.29 11.03 14 378268 480 110210537
Generalised tonic-clonic seizure 17.29 11.03 273 378009 54407 110156610
Japanese spotted fever 17.28 11.03 6 378276 31 110210986
Respiratory papilloma 17.28 11.03 6 378276 31 110210986
HELLP syndrome 17.27 11.03 18 378264 858 110210159
Hypocomplementaemia 17.27 11.03 12 378270 325 110210692
Tuberculosis liver 17.26 11.03 8 378274 96 110210921
Joint effusion 17.26 11.03 28 378254 20877 110190140
Treatment noncompliance 17.24 11.03 348 377934 72642 110138375
Respiration abnormal 17.23 11.03 6 378276 9803 110201214
Motor dysfunction 17.21 11.03 36 378246 24370 110186647
Skin cancer 17.20 11.03 112 378170 17672 110193345
Decreased activity 17.17 11.03 8 378274 10966 110200051
Sphincter of Oddi dysfunction 17.15 11.03 15 378267 573 110210444
Familial mediterranean fever 17.14 11.03 10 378272 198 110210819
Biliary fistula 17.13 11.03 9 378273 144 110210873
Porocarcinoma 17.12 11.03 6 378276 32 110210985
Meningitis histoplasma 17.12 11.03 6 378276 32 110210985
Accident 17.11 11.03 8 378274 10944 110200073
Leukocytosis 17.11 11.03 269 378013 53559 110157458
Keratitis viral 17.05 11.03 5 378277 13 110211004
Acquired porokeratosis 17.05 11.03 5 378277 13 110211004
Oropharyngeal squamous cell carcinoma 17.04 11.03 12 378270 332 110210685
Parotitis 16.99 11.03 35 378247 3118 110207899
Orbital apex syndrome 16.97 11.03 8 378274 100 110210917
Hepatobiliary infection 16.97 11.03 6 378276 33 110210984
Myocarditis toxoplasmal 16.96 11.03 7 378275 62 110210955
Bronchopulmonary aspergillosis allergic 16.92 11.03 4 378278 8422 110202595
Gingival bleeding 16.92 11.03 26 378256 19813 110191204
Cerebral mass effect 16.92 11.03 30 378252 2389 110208628
Epstein-Barr virus antigen positive 16.90 11.03 8 378274 101 110210916
Overlap syndrome 16.87 11.03 5 378277 9054 110201963
Respiratory rate increased 16.85 11.03 38 378244 25045 110185972
Jejunal perforation 16.83 11.03 13 378269 416 110210601
Erythrophagocytosis 16.82 11.03 6 378276 34 110210983
Fungal test positive 16.78 11.03 20 378262 1107 110209910
Argentine haemorrhagic fever 16.78 11.03 5 378277 14 110211003
Iron overload 16.78 11.03 28 378254 2123 110208894
Mucosal necrosis 16.75 11.03 10 378272 207 110210810
Thyroid disorder 16.74 11.03 20 378262 16949 110194068
Henoch-Schonlein purpura 16.73 11.03 38 378244 3619 110207398
Small cell carcinoma 16.64 11.03 12 378270 345 110210672
Metastatic neoplasm 16.60 11.03 51 378231 5822 110205195
Page kidney 16.58 11.03 7 378275 66 110210951
Necrotising colitis 16.56 11.03 25 378257 1740 110209277
Enterocolitis fungal 16.54 11.03 6 378276 36 110210981
Drug level 16.53 11.03 5 378277 15 110211002
Spontaneous intrahepatic portosystemic venous shunt 16.53 11.03 5 378277 15 110211002
Bartonella test positive 16.53 11.03 5 378277 15 110211002
Groin pain 16.52 11.03 17 378265 15411 110195606
Product administration interrupted 16.52 11.03 9 378273 11283 110199734
Paradoxical drug reaction 16.50 11.03 72 378210 9745 110201272
Microtia 16.50 11.03 4 378278 3 110211014
Organ transplant 16.50 11.03 4 378278 3 110211014
Fungating wound 16.49 11.03 7 378275 67 110210950
Sebaceous gland disorder 16.49 11.03 7 378275 67 110210950
Encephalitis Japanese B 16.49 11.03 7 378275 67 110210950
Pelvic venous thrombosis 16.47 11.03 32 378250 2732 110208285
Stenotrophomonas bacteraemia 16.46 11.03 11 378271 279 110210738
Multi-organ disorder 16.45 11.03 36 378246 3345 110207672
Blood stem cell transplant failure 16.44 11.03 16 378266 702 110210315
Tongue oedema 16.42 11.03 4 378278 8252 110202765
Schizophrenia 16.41 11.03 31 378251 21795 110189222
Acinetobacter test positive 16.36 11.03 11 378271 282 110210735
Candida pneumonia 16.35 11.03 19 378263 1024 110209993
T-lymphocyte count decreased 16.34 11.03 15 378267 611 110210406
Ventricular tachycardia 16.33 11.03 102 378180 49907 110161110
Optic discs blurred 16.31 11.03 7 378275 69 110210948
Oesophagitis 16.30 11.03 160 378122 28555 110182462
Metastases to pleura 16.29 11.03 27 378255 2036 110208981
Funguria 16.29 11.03 5 378277 16 110211001
Lacrimal gland enlargement 16.26 11.03 6 378276 38 110210979
Pathergy reaction 16.22 11.03 7 378275 70 110210947
Linear IgA disease 16.22 11.03 42 378240 4347 110206670
Achromobacter infection 16.19 11.03 11 378271 287 110210730
Lymphoid tissue hyperplasia 16.19 11.03 11 378271 287 110210730
Papilloma 16.18 11.03 14 378268 527 110210490
Asymptomatic bacteriuria 16.18 11.03 13 378269 441 110210576
Streptococcal infection 16.17 11.03 77 378205 10813 110200204
Splenic lesion 16.16 11.03 15 378267 620 110210397
Eyelid oedema 16.13 11.03 17 378265 15245 110195772
Hair follicle tumour benign 16.13 11.03 13 378269 443 110210574
Hepatic cytolysis 16.12 11.03 116 378166 54937 110156080
Urinary tract infection fungal 16.11 11.03 21 378261 1274 110209743
Avian influenza 16.11 11.03 8 378274 113 110210904
Breast pain 16.10 11.03 7 378275 9993 110201024
Wound sepsis 16.09 11.03 10 378272 223 110210794
Blood urine present 16.07 11.03 37 378245 24208 110186809
Arteriovenous fistula aneurysm 16.06 11.03 5 378277 17 110211000
Reactive gastropathy 16.02 11.03 16 378266 725 110210292
Blood culture positive 15.99 11.03 67 378215 8909 110202108
Infusion site extravasation 15.99 11.03 10 378272 11624 110199393
Gastroenteritis viral 15.98 11.03 54 378228 31172 110179845
Retroperitonitis 15.97 11.03 4 378278 4 110211013
Insulin resistant diabetes 15.97 11.03 4 378278 4 110211013
Extranodal marginal zone B-cell lymphoma (MALT type) stage IV 15.97 11.03 4 378278 4 110211013
Fascioliasis 15.97 11.03 4 378278 4 110211013
Malignant neoplasm of conjunctiva 15.97 11.03 7 378275 73 110210944
Q fever 15.89 11.03 11 378271 296 110210721
Tooth fracture 15.89 11.03 13 378269 13154 110197863
Sebaceous adenoma 15.88 11.03 6 378276 41 110210976
Blood pressure abnormal 15.87 11.03 33 378249 22391 110188626
Myocardial necrosis 15.87 11.03 14 378268 541 110210476
Lymphangitis 15.80 11.03 23 378259 1549 110209468
Biopsy liver abnormal 15.80 11.03 13 378269 456 110210561
Blood pressure ambulatory increased 15.80 11.03 7 378275 75 110210942
Glomerular filtration rate decreased 15.79 11.03 160 378122 28796 110182221
Ligament sprain 15.78 11.03 19 378263 16049 110194968
Anal fissure 15.78 11.03 7 378275 9874 110201143
Upper airway necrosis 15.76 11.03 6 378276 42 110210975
Concussion 15.74 11.03 10 378272 11528 110199489
Haemarthrosis 15.70 11.03 3 378279 7326 110203691
Enamel anomaly 15.67 11.03 10 378272 234 110210783
Hyperviscosity syndrome 15.66 11.03 14 378268 551 110210466
Pharyngeal swelling 15.64 11.03 11 378271 12021 110198996
Sarcomatoid carcinoma 15.64 11.03 6 378276 43 110210974
Hypertensive encephalopathy 15.63 11.03 20 378262 1191 110209826
Splenic peliosis 15.63 11.03 5 378277 19 110210998
Peritoneal candidiasis 15.63 11.03 5 378277 19 110210998
Cryptitis 15.61 11.03 12 378270 381 110210636
Sensation of foreign body 15.60 11.03 4 378278 7971 110203046
Resting tremor 15.59 11.03 24 378258 1699 110209318
Schistocytosis 15.56 11.03 7 378275 78 110210939
Ischaemia 15.56 11.03 67 378215 9016 110202001
Total cholesterol/HDL ratio abnormal 15.56 11.03 7 378275 78 110210939
Actinomycosis 15.55 11.03 21 378261 1319 110209698
Herpes simplex reactivation 15.52 11.03 22 378260 1446 110209571
Acid base balance abnormal 15.52 11.03 13 378269 468 110210549
Hyperamylasaemia 15.50 11.03 20 378262 1201 110209816
Hepatic vein thrombosis 15.45 11.03 11 378271 310 110210707
Tropical spastic paresis 15.43 11.03 5 378277 20 110210997
Laryngeal mass 15.40 11.03 7 378275 80 110210937
Pneumonia respiratory syncytial viral 15.39 11.03 31 378251 2718 110208299
Oligoarthritis 15.31 11.03 16 378266 765 110210252
Vascular compression 15.31 11.03 16 378266 765 110210252
Leuconostoc infection 15.29 11.03 6 378276 46 110210971
Tongue necrosis 15.28 11.03 8 378274 127 110210890
High-grade B-cell lymphoma 15.27 11.03 10 378272 245 110210772
Haemoglobin decreased 15.26 11.03 695 377587 248032 109962985
Septic encephalopathy 15.24 11.03 12 378270 395 110210622
Ventricular fibrillation 15.24 11.03 81 378201 41232 110169785
Angiosarcoma recurrent 15.24 11.03 5 378277 21 110210996
Blood lactic acid increased 15.23 11.03 19 378263 15802 110195215
Pericarditis infective 15.23 11.03 10 378272 246 110210771
Essential hypertension 15.23 11.03 4 378278 7843 110203174
Flavobacterium infection 15.22 11.03 8 378274 128 110210889
Bundle branch block left 15.21 11.03 13 378269 12875 110198142
Transient acantholytic dermatosis 15.20 11.03 11 378271 318 110210699
Pyonephrosis 15.17 11.03 9 378273 184 110210833
Oral disorder 15.10 11.03 81 378201 11922 110199095
Dystonia 15.08 11.03 42 378240 25763 110185254
Splenic rupture 15.07 11.03 30 378252 2607 110208410
Peritoneal dialysis 15.07 11.03 17 378265 887 110210130
Hereditary angioedema 15.06 11.03 3 378279 7111 110203906
Blindness cortical 15.05 11.03 19 378263 1116 110209901
Hypertrichosis 15.03 11.03 24 378258 1754 110209263
Nerve injury 15.01 11.03 9 378273 10704 110200313
Procedural pneumothorax 15.01 11.03 8 378274 132 110210885
Ureteric obstruction 14.97 11.03 33 378249 3081 110207936
Nephrogenic systemic fibrosis 14.93 11.03 47 378235 5436 110205581
Neurological symptom 14.91 11.03 98 378184 15510 110195507
Bradyphrenia 14.89 11.03 11 378271 11717 110199300
Marrow hyperplasia 14.85 11.03 24 378258 1772 110209245
Wound evisceration 14.85 11.03 8 378274 135 110210882
Renal hypertension 14.85 11.03 10 378272 257 110210760
Dyspnoea at rest 14.84 11.03 5 378277 8341 110202676
Arteriovenous fistula site infection 14.83 11.03 9 378273 192 110210825
Enterobacter pneumonia 14.83 11.03 14 378268 591 110210426
Portal fibrosis 14.83 11.03 15 378267 690 110210327
Vascular graft thrombosis 14.81 11.03 10 378272 258 110210759
Tuberculous pleurisy 14.81 11.03 15 378267 691 110210326
Chronic active Epstein-Barr virus infection 14.79 11.03 8 378274 136 110210881
Autoimmune hepatitis 14.79 11.03 94 378188 14710 110196307
Knee operation 14.78 11.03 3 378279 7019 110203998
Blood sodium decreased 14.77 11.03 74 378208 38245 110172772
Quadriplegia 14.75 11.03 39 378243 4088 110206929
Autoimmune neutropenia 14.72 11.03 15 378267 696 110210321
Mucosal inflammation 14.72 11.03 432 377850 95709 110115308
Anastomotic complication 14.72 11.03 14 378268 597 110210420
Vestibular nystagmus 14.70 11.03 4 378278 7 110211010
Endocarditis viral 14.70 11.03 4 378278 7 110211010
St. Louis encephalitis 14.70 11.03 4 378278 7 110211010
Sinus perforation 14.70 11.03 4 378278 7 110211010
Mucinous adenocarcinoma of appendix 14.70 11.03 5 378277 24 110210993
Steatohepatitis 14.70 11.03 20 378262 1265 110209752
Hemianopia heteronymous 14.68 11.03 7 378275 90 110210927
Chorioretinitis 14.66 11.03 21 378261 1394 110209623
Incorrect product administration duration 14.65 11.03 30 378252 20468 110190549
Myeloma cast nephropathy 14.64 11.03 10 378272 263 110210754
Systemic viral infection 14.64 11.03 8 378274 139 110210878
Corynebacterium bacteraemia 14.63 11.03 9 378273 197 110210820
Bladder transitional cell carcinoma stage III 14.56 11.03 6 378276 53 110210964
Mydriasis 14.54 11.03 34 378248 22123 110188894
Septal panniculitis 14.54 11.03 8 378274 141 110210876
Varicose vein 14.53 11.03 3 378279 6937 110204080
Abdominal lymphadenopathy 14.53 11.03 24 378258 1804 110209213
Immune recovery uveitis 14.49 11.03 8 378274 142 110210875
Pulmonary granuloma 14.48 11.03 29 378253 2532 110208485
Medical device site abscess 14.47 11.03 9 378273 201 110210816
Pneumonia haemophilus 14.47 11.03 30 378252 2685 110208332
Lung squamous cell carcinoma stage IV 14.46 11.03 6 378276 54 110210963
Eye infection 14.44 11.03 17 378265 14501 110196516
Hypoproteinaemia 14.43 11.03 49 378233 5896 110205121
Seborrhoeic keratosis 14.42 11.03 33 378249 3159 110207858
Tooth hypoplasia 14.40 11.03 11 378271 346 110210671
Colitis herpes 14.37 11.03 5 378277 26 110210991
Cervical spinal cord paralysis 14.37 11.03 5 378277 26 110210991
Capnocytophaga sepsis 14.37 11.03 5 378277 26 110210991
External ear neoplasm malignant 14.37 11.03 5 378277 26 110210991
Portal vein stenosis 14.37 11.03 5 378277 26 110210991
Primary syphilis 14.37 11.03 5 378277 26 110210991
CSF culture positive 14.36 11.03 6 378276 55 110210962
Parapox virus infection 14.36 11.03 4 378278 8 110211009
Varicella keratitis 14.36 11.03 4 378278 8 110211009
Burkholderia pseudomallei infection 14.34 11.03 8 378274 145 110210872
Candida endophthalmitis 14.32 11.03 9 378273 205 110210812
Keratoacanthoma 14.29 11.03 21 378261 1427 110209590
Aeromonas infection 14.28 11.03 13 378269 524 110210493
Inflammatory pseudotumour 14.28 11.03 7 378275 96 110210921
Atelectasis 14.26 11.03 190 378092 36522 110174495
Nasal oedema 14.23 11.03 3 378279 6836 110204181
Myopathy toxic 14.22 11.03 20 378262 1305 110209712
Psychomotor hyperactivity 14.22 11.03 30 378252 20247 110190770
Echinococciasis 14.22 11.03 5 378277 27 110210990
Biliary tract infection 14.20 11.03 23 378259 1701 110209316
Enteritis infectious 14.20 11.03 37 378245 3845 110207172
Milk-alkali syndrome 14.19 11.03 25 378257 1980 110209037
Metastases to central nervous system 14.19 11.03 36 378246 22781 110188236
Infusion site erythema 14.19 11.03 12 378270 11947 110199070
Otitis externa 14.19 11.03 30 378252 2722 110208295
Incorrect dose administered by device 14.16 11.03 3 378279 6811 110204206
Clear cell renal cell carcinoma 14.16 11.03 30 378252 2726 110208291
Secretion discharge 14.15 11.03 30 378252 20214 110190803
Red cell distribution width increased 14.14 11.03 24 378258 17578 110193439
Tooth loss 14.14 11.03 5 378277 8091 110202926
Muscle rigidity 14.13 11.03 39 378243 23992 110187025
Hypocalcaemia 14.12 11.03 149 378133 65217 110145800
Gastroduodenal ulcer 14.08 11.03 17 378265 954 110210063
Papillary renal cell carcinoma 14.08 11.03 11 378271 358 110210659
Skin weeping 14.07 11.03 36 378246 3699 110207318
Dry throat 14.05 11.03 7 378275 9231 110201786
Cystinosis 14.04 11.03 3 378279 0 110211017
Burkitt's leukaemia 14.04 11.03 3 378279 0 110211017
Aprosody 14.04 11.03 3 378279 0 110211017
Subvalvular aortic stenosis 14.04 11.03 3 378279 0 110211017
Pulmonary sensitisation 14.04 11.03 3 378279 0 110211017
Retroperitoneal effusion 14.04 11.03 3 378279 0 110211017
Abdominal wall neoplasm 14.04 11.03 3 378279 0 110211017
Anti-HLA antibody test positive 14.04 11.03 3 378279 0 110211017
Dientamoeba infection 14.04 11.03 3 378279 0 110211017
Pneumonia proteus 14.04 11.03 3 378279 0 110211017
Lymphoid hyperplasia of intestine 14.04 11.03 3 378279 0 110211017
Oropharyngeal lymphoid hyperplasia 14.04 11.03 3 378279 0 110211017
Herpes sepsis 14.04 11.03 4 378278 9 110211008
Anorectal infection bacterial 14.04 11.03 4 378278 9 110211008
ABO incompatibility 14.04 11.03 4 378278 9 110211008
Diffuse large B-cell lymphoma stage III 14.02 11.03 7 378275 100 110210917
Peripancreatic fluid collection 14.02 11.03 7 378275 100 110210917
Oropharyngeal discomfort 14.02 11.03 9 378273 10318 110200699
Neuropsychiatric syndrome 13.98 11.03 9 378273 214 110210803
Portal vein embolism 13.96 11.03 7 378275 101 110210916
Inferior vena caval occlusion 13.96 11.03 7 378275 101 110210916
Inappropriate antidiuretic hormone secretion 13.91 11.03 177 378105 33674 110177343
CNS ventriculitis 13.89 11.03 14 378268 641 110210376
Venous haemorrhage 13.87 11.03 11 378271 366 110210651
Pulmonary valve stenosis 13.87 11.03 8 378274 155 110210862
Apallic syndrome 13.86 11.03 18 378264 1088 110209929
Amyloidosis senile 13.84 11.03 7 378275 103 110210914
Subarachnoid haemorrhage 13.82 11.03 159 378123 29543 110181474
Retinal vasculitis 13.80 11.03 25 378257 2024 110208993
Blood lactate dehydrogenase 13.78 11.03 5 378277 30 110210987
Metastases to abdominal cavity 13.77 11.03 16 378266 862 110210155
Joint tuberculosis 13.76 11.03 9 378273 220 110210797
Infective myositis 13.76 11.03 9 378273 220 110210797
Haematoma infection 13.75 11.03 22 378260 1610 110209407
Carotid artery perforation 13.75 11.03 4 378278 10 110211007
Respiratory disorder 13.74 11.03 167 378115 71215 110139802
Premature labour 13.72 11.03 65 378217 9107 110201910
Metastases to muscle 13.67 11.03 11 378271 374 110210643
Cardiac index increased 13.64 11.03 5 378277 31 110210986
Endotoxic shock 13.64 11.03 5 378277 31 110210986
Splenic infection fungal 13.60 11.03 8 378274 161 110210856
Blood 25-hydroxycholecalciferol decreased 13.60 11.03 12 378270 464 110210553
Malnutrition 13.58 11.03 148 378134 27131 110183886
Eyelid irritation 13.54 11.03 18 378264 1113 110209904
Retinal scar 13.53 11.03 12 378270 467 110210550
Ureteric cancer 13.53 11.03 10 378272 299 110210718
Mucosal ulceration 13.52 11.03 27 378255 2352 110208665
Aortic rupture 13.51 11.03 9 378273 227 110210790
Typhoid fever 13.49 11.03 7 378275 109 110210908
Infertility male 13.49 11.03 7 378275 109 110210908
Hepatitis G 13.49 11.03 7 378275 109 110210908
Anorectal varices 13.49 11.03 6 378276 65 110210952
Blood thyroid stimulating hormone decreased 13.47 11.03 4 378278 7235 110203782
Strabismus 13.47 11.03 34 378248 3465 110207552
Onychoclasis 13.47 11.03 4 378278 7233 110203784
Eye disorder 13.46 11.03 52 378230 28854 110182163
Pustular psoriasis 13.46 11.03 16 378266 13589 110197428
Metastases to peritoneum 13.41 11.03 46 378236 5564 110205453
Acanthosis 13.38 11.03 13 378269 569 110210448
Postoperative hypertension 13.38 11.03 5 378277 33 110210984
Chronic myeloid leukaemia recurrent 13.37 11.03 11 378271 386 110210631
Epileptic encephalopathy 13.37 11.03 14 378268 671 110210346
Erythema multiforme 13.35 11.03 33 378249 21064 110189953
Injection site urticaria 13.35 11.03 24 378258 17191 110193826
Delusional disorder, erotomanic type 13.33 11.03 6 378276 67 110210950
Neurocryptococcosis 13.33 11.03 6 378276 67 110210950
Skin hyperpigmentation 13.28 11.03 62 378220 8634 110202383
B-lymphocyte abnormalities 13.26 11.03 8 378274 169 110210848
Varicella virus test positive 13.25 11.03 11 378271 391 110210626
Viral myositis 13.25 11.03 6 378276 68 110210949
Terminal ileitis 13.24 11.03 22 378260 1662 110209355
Renal vascular resistance increased 13.22 11.03 4 378278 12 110211005
Anti-interferon antibody positive 13.22 11.03 4 378278 12 110211005
Bile duct cancer recurrent 13.22 11.03 4 378278 12 110211005
Dermatitis papillaris capillitii 13.22 11.03 4 378278 12 110211005
Narrow anterior chamber angle 13.21 11.03 8 378274 170 110210847
Drooling 13.18 11.03 4 378278 7135 110203882
Pleomorphic malignant fibrous histiocytoma 13.13 11.03 5 378277 35 110210982
Cervical dysplasia 13.13 11.03 29 378253 2711 110208306
Ventricular extrasystoles 13.12 11.03 37 378245 22604 110188413
Ulcerative keratitis 13.12 11.03 41 378241 4725 110206292
Arteriosclerosis 13.09 11.03 136 378146 24631 110186386
Hospice care 13.07 11.03 14 378268 12459 110198558
Gestational diabetes 13.04 11.03 55 378227 7334 110203683
Immobile 13.04 11.03 5 378277 7697 110203320
Intentional dose omission 13.03 11.03 31 378251 20049 110190968
Sinusitis bacterial 13.02 11.03 27 378255 2417 110208600
Restless legs syndrome 13.01 11.03 42 378240 24584 110186433
Severe acute respiratory syndrome 13.01 11.03 9 378273 242 110210775
Skin abrasion 12.99 11.03 22 378260 16129 110194888
Bronchopneumopathy 12.99 11.03 16 378266 917 110210100
Iliac artery disease 12.98 11.03 4 378278 13 110211004
Parotid abscess 12.98 11.03 4 378278 13 110211004
Splenic haemorrhage 12.96 11.03 15 378267 805 110210212
Psychomotor skills impaired 12.95 11.03 4 378278 7054 110203963
Infective tenosynovitis 12.95 11.03 12 378270 495 110210522
Radiculitis brachial 12.95 11.03 6 378276 72 110210945
Therapy change 12.94 11.03 68 378214 9929 110201088
Raoultella ornithinolytica infection 12.93 11.03 8 378274 177 110210840
Biopsy kidney 12.91 11.03 9 378273 245 110210772
Necrotising fasciitis fungal 12.89 11.03 5 378277 37 110210980
Infusion site swelling 12.88 11.03 9 378273 9868 110201149
Metastases to spinal cord 12.88 11.03 9 378273 246 110210771
Autoimmune enteropathy 12.87 11.03 6 378276 73 110210944
Cerebral haemorrhage 12.87 11.03 302 377980 64666 110146351
Initial insomnia 12.86 11.03 10 378272 10379 110200638
Osteomalacia 12.84 11.03 21 378261 1566 110209451
Antipsychotic drug level increased 12.83 11.03 4 378278 7011 110204006
Polyneuropathy 12.82 11.03 61 378221 31951 110179066
Acute oesophageal mucosal lesion 12.81 11.03 8 378274 180 110210837
Brown-Sequard syndrome 12.80 11.03 6 378276 74 110210943
Herpes zoster meningitis 12.78 11.03 9 378273 249 110210768
Human herpes virus 6 serology positive 12.78 11.03 9 378273 249 110210768
Diarrhoea 12.78 11.03 3588 374694 1135917 109075100
Neurological decompensation 12.75 11.03 52 378230 6831 110204186
Tuberculoma of central nervous system 12.75 11.03 13 378269 604 110210413
Renal artery occlusion 12.73 11.03 8 378274 182 110210835
Scoliosis 12.72 11.03 7 378275 8726 110202291
Mesenteric artery thrombosis 12.72 11.03 16 378266 937 110210080
Abnormal dreams 12.67 11.03 15 378267 12765 110198252
Blood thyroid stimulating hormone increased 12.67 11.03 14 378268 12287 110198730
Necrotising soft tissue infection 12.63 11.03 12 378270 511 110210506
Seroma 12.63 11.03 32 378250 3269 110207748
Disorientation 12.61 11.03 168 378114 70503 110140514
Pulse absent 12.60 11.03 12 378270 11280 110199737
Fracture 12.60 11.03 43 378239 24745 110186272
Anti-GAD antibody positive 12.59 11.03 6 378276 77 110210940
Upper motor neurone lesion 12.58 11.03 10 378272 334 110210683
Oesophageal squamous cell carcinoma stage IV 12.54 11.03 4 378278 15 110211002
Reticulocyte count decreased 12.54 11.03 16 378266 950 110210067
Accidental overdose 12.52 11.03 115 378167 51719 110159298
Wrong technique in device usage process 12.51 11.03 4 378278 6897 110204120
Neurofibrosarcoma 12.47 11.03 9 378273 259 110210758
Enterobacter sepsis 12.43 11.03 19 378263 1337 110209680
Keratitis fungal 12.41 11.03 11 378271 428 110210589
Creatinine renal clearance decreased 12.38 11.03 36 378246 21779 110189238
Leukaemic infiltration extramedullary 12.37 11.03 10 378272 342 110210675
Ear neoplasm malignant 12.35 11.03 7 378275 131 110210886
Renal artery perforation 12.34 11.03 4 378278 16 110211001
Amyloidosis 12.34 11.03 31 378251 3150 110207867
Abdominal compartment syndrome 12.34 11.03 23 378259 1904 110209113
Campylobacter gastroenteritis 12.32 11.03 23 378259 1906 110209111
Carotid artery thrombosis 12.28 11.03 9 378273 9629 110201388
Skin necrosis 12.28 11.03 120 378162 21392 110189625
Vaginal dysplasia 12.25 11.03 5 378277 43 110210974
Spleen tuberculosis 12.25 11.03 5 378277 43 110210974
Blood pressure diastolic increased 12.23 11.03 29 378253 18778 110192239
Rhinitis 12.23 11.03 38 378244 22507 110188510
Dermatitis contact 12.18 11.03 18 378264 13935 110197082
Rhinitis allergic 12.17 11.03 27 378255 17895 110193122
Varicella zoster sepsis 12.15 11.03 4 378278 17 110211000
Peritonitis lupus 12.15 11.03 4 378278 17 110211000
Gingival ulceration 12.15 11.03 18 378264 1232 110209785
Thyroid stimulating hormone deficiency 12.15 11.03 5 378277 44 110210973
Cancer pain 12.14 11.03 4 378278 6768 110204249
Intestinal metastasis 12.14 11.03 12 378270 537 110210480
Sinus node dysfunction 12.12 11.03 8 378274 9039 110201978
Primary hyperaldosteronism 12.12 11.03 9 378273 271 110210746
Glucose tolerance impaired 12.11 11.03 66 378216 9771 110201246
N-terminal prohormone brain natriuretic peptide increased 12.11 11.03 3 378279 6118 110204899
Precursor T-lymphoblastic lymphoma/leukaemia 12.07 11.03 7 378275 137 110210880
Skin discomfort 12.06 11.03 24 378258 2086 110208931
Granulomatous lymphadenitis 12.03 11.03 11 378271 446 110210571
Bacterial disease carrier 12.01 11.03 25 378257 2244 110208773
Biliary anastomosis 11.98 11.03 3 378279 3 110211014
Sustained viral response 11.98 11.03 3 378279 3 110211014
Visual agnosia 11.98 11.03 3 378279 3 110211014
Pseudoxanthoma elasticum 11.98 11.03 3 378279 3 110211014
Systemic bartonellosis 11.98 11.03 3 378279 3 110211014
Brachyspira infection 11.98 11.03 3 378279 3 110211014
Panel-reactive antibody increased 11.98 11.03 3 378279 3 110211014
Exserohilum infection 11.98 11.03 3 378279 3 110211014
Extravasation of urine 11.98 11.03 3 378279 3 110211014
Removal of transplanted organ 11.98 11.03 3 378279 3 110211014
West Nile virus test positive 11.98 11.03 3 378279 3 110211014
Iliac artery rupture 11.98 11.03 3 378279 3 110211014
Sialocele 11.98 11.03 3 378279 3 110211014
Endocrine pancreatic disorder 11.98 11.03 3 378279 3 110211014
Thrombasthenia 11.98 11.03 3 378279 3 110211014
Hantavirus pulmonary infection 11.98 11.03 3 378279 3 110211014
Drug level therapeutic 11.98 11.03 3 378279 3 110211014
Bronchitis fungal 11.98 11.03 3 378279 3 110211014
Aeromonas test positive 11.98 11.03 3 378279 3 110211014
Renal transplant torsion 11.98 11.03 3 378279 3 110211014
Tonsillar neoplasm 11.97 11.03 4 378278 18 110210999
Diffuse panbronchiolitis 11.95 11.03 5 378277 46 110210971
Visual evoked potentials abnormal 11.95 11.03 5 378277 46 110210971
Decubitus ulcer 11.95 11.03 28 378254 18208 110192809
Fistula repair 11.94 11.03 6 378276 87 110210930
Metastases to abdominal wall 11.93 11.03 8 378274 204 110210813
Intention tremor 11.91 11.03 15 378267 879 110210138
Oesophageal infection 11.91 11.03 14 378268 764 110210253
Oral pain 11.90 11.03 77 378205 37367 110173650
Laryngeal cancer 11.89 11.03 14 378268 765 110210252
Chronic cutaneous lupus erythematosus 11.87 11.03 16 378266 1003 110210014
Mononeuropathy 11.87 11.03 10 378272 363 110210654
Therapeutic product ineffective 11.85 11.03 27 378255 2577 110208440
Measles 11.84 11.03 13 378269 658 110210359
Neisseria infection 11.83 11.03 8 378274 207 110210810
Skin bacterial infection 11.82 11.03 15 378267 886 110210131
Ocular lymphoma 11.76 11.03 8 378274 209 110210808
Cord blood transplant therapy 11.76 11.03 6 378276 90 110210927
Cellulitis orbital 11.74 11.03 16 378266 1014 110210003
Atrophy 11.72 11.03 26 378256 2438 110208579
Gastrointestinal viral infection 11.70 11.03 21 378261 1688 110209329
Culture positive 11.69 11.03 17 378265 1144 110209873
Meningitis listeria 11.65 11.03 18 378264 1279 110209738
Cerebrovascular insufficiency 11.64 11.03 7 378275 147 110210870
Micturition urgency 11.62 11.03 31 378251 19289 110191728
Coombs positive haemolytic anaemia 11.60 11.03 20 378262 1557 110209460
Tracheitis 11.60 11.03 21 378261 1700 110209317
Proctalgia 11.59 11.03 17 378265 13205 110197812
Mean cell haemoglobin concentration 11.59 11.03 5 378277 50 110210967
Pantoea agglomerans infection 11.55 11.03 7 378275 149 110210868
Incorrect dose administered 11.55 11.03 268 378014 103373 110107644
Alanine aminotransferase abnormal 11.53 11.03 9 378273 9325 110201692
Pleurisy 11.53 11.03 76 378206 12040 110198977
Segmented hyalinising vasculitis 11.53 11.03 6 378276 94 110210923
Seroconversion test positive 11.50 11.03 5 378277 51 110210966
Portal vein flow decreased 11.50 11.03 5 378277 51 110210966
Bronchoalveolar lavage abnormal 11.50 11.03 10 378272 379 110210638
Granulocytopenia 11.49 11.03 16 378266 12699 110198318
Poor venous access 11.49 11.03 44 378238 24478 110186539
Eosinophilic oesophagitis 11.49 11.03 18 378264 1294 110209723
Acute graft versus host disease oral 11.47 11.03 6 378276 95 110210922
Paracoccidioides infection 11.47 11.03 6 378276 95 110210922
Skin hypopigmentation 11.47 11.03 19 378263 1432 110209585
Pancreatic pseudoaneurysm 11.42 11.03 6 378276 96 110210921
Parasitic encephalitis 11.42 11.03 5 378277 52 110210965
Fibrosarcoma 11.42 11.03 5 378277 52 110210965
Herpes simplex meningitis 11.42 11.03 6 378276 96 110210921
Joint abscess 11.37 11.03 13 378269 688 110210329
Drug half-life increased 11.36 11.03 9 378273 299 110210718
Abscess bacterial 11.36 11.03 15 378267 922 110210095
Affective disorder 11.35 11.03 13 378269 11228 110199789
Beta 2 microglobulin urine increased 11.35 11.03 7 378275 154 110210863
Lung squamous cell carcinoma stage II 11.31 11.03 4 378278 22 110210995
Arthritis reactive 11.31 11.03 14 378268 806 110210211
Medical device site cellulitis 11.31 11.03 8 378274 223 110210794
Pleural mesothelioma 11.31 11.03 6 378276 98 110210919
Retinal thickening 11.31 11.03 9 378273 301 110210716
Symptom recurrence 11.29 11.03 39 378243 4733 110206284
Toxic shock syndrome streptococcal 11.23 11.03 9 378273 304 110210713
Bursitis infective 11.23 11.03 19 378263 1457 110209560
Urethral stenosis 11.22 11.03 17 378265 1187 110209830
Cholangitis acute 11.22 11.03 22 378260 1891 110209126
Hypomania 11.22 11.03 11 378271 10199 110200818
Pneumaturia 11.17 11.03 5 378277 55 110210962
Large cell lung cancer 11.17 11.03 4 378278 23 110210994
Small intestinal haemorrhage 11.15 11.03 38 378244 4580 110206437
Arm amputation 11.15 11.03 7 378275 159 110210858
Euglycaemic diabetic ketoacidosis 11.15 11.03 14 378268 11609 110199408
Diabetic neuropathy 11.11 11.03 5 378277 6994 110204023
Echopraxia 11.09 11.03 5 378277 56 110210961
Proctitis 11.09 11.03 26 378256 16901 110194116
Condition aggravated 11.08 11.03 2282 376000 732554 109478463
Subdural haematoma 11.07 11.03 76 378206 36378 110174639
Cold type haemolytic anaemia 11.06 11.03 11 378271 496 110210521
Lemierre syndrome 11.04 11.03 7 378275 162 110210855
Rectal prolapse 11.03 11.03 26 378256 2537 110208480
Glomerulonephritis acute 11.03 11.03 9 378273 312 110210705

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D11AH01 DERMATOLOGICALS
OTHER DERMATOLOGICAL PREPARATIONS
OTHER DERMATOLOGICAL PREPARATIONS
Agents for dermatitis, excluding corticosteroids
ATC L04AD02 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Calcineurin inhibitors
FDA EPC N0000175457 Calcineurin Inhibitor Immunosuppressant
FDA MoA N0000175458 Calcineurin Inhibitors
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D007155 Immunologic Factors
MeSH PA D007166 Immunosuppressive Agents
MeSH PA D065095 Calcineurin Inhibitors
CHEBI has role CHEBI:35705 immunosuppressive agent
CHEBI has role CHEBI:22587 antiviral agent
CHEBI has role CHEBI:35441 antiinfective agent
CHEBI has role CHEBI:35526 hypoglycemic agent
CHEBI has role CHEBI:35554 cardiovascular drug
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35674 antihypertensive agent
CHEBI has role CHEBI:35718 antifungal agent
CHEBI has role CHEBI:35842 antirheumatic drug
CHEBI has role CHEBI:50177 dermatologic drug
CHEBI has role CHEBI:50748 antipsoriatic
CHEBI has role CHEBI:65023 anti-asthmatic agent
CHEBI has role CHEBI:66981 ophthalmology drug
CHEBI has role CHEBI:67079 anti-inflammatory agent
CHEBI has role CHEBI:73336 vulnerary
CHEBI has role CHEBI:75835 anti-anaemic agent
CHEBI has role CHEBI:76595 nephroprotective agent
CHEBI has role CHEBI:231911 renoprotective agent
CHEBI has role CHEBI:233423 antifibrotic agent

Related Drugs by ATC class:

D11AH Agents for dermatitis, excluding corticosteroids 11 drugs
abrocitinibalitretinoincrisaborolecromoglicic aciddelgocitinibdupilumablebrikizumabnemolizumabpimecrolimusruxolitinibtralokinumab
L04AD Calcineurin inhibitors 2 drugs
ciclosporinvoclosporin

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Atopic dermatitis indication 24079001 DOID:3310
Transplanted organ rejection indication 213148006
Liver transplant rejection indication 235911006
Renal transplant rejection indication 236570004
Prevention of Cardiac Transplant Rejection indication
Prevention of Transplant Rejection indication
Prevention of Liver Transplant Rejection indication
Intractable Eczema indication
Prevention of Kidney Transplant Rejection indication
Prevention of Lung Transplant Rejection off-label use
Delirium contraindication 2776000
Herpes zoster contraindication 4740000 DOID:8536
Hyperkalemia contraindication 14140009
Progressive multifocal leukoencephalopathy contraindication 22255007 DOID:643
Constitutional aplastic anemia contraindication 28975000 DOID:1342
Lymphadenopathy contraindication 30746006
Torsades de pointes contraindication 31722008
Immunosuppression contraindication 38013005
Hypertensive disorder contraindication 38341003 DOID:10763
Infectious disease contraindication 40733004
Mental handicap contraindication 47437004
Chronic heart failure contraindication 48447003
Left ventricular hypertrophy contraindication 55827005
Hepatic failure contraindication 59927004
Diabetes mellitus contraindication 73211009 DOID:9351
Hyperglycemia contraindication 80394007 DOID:4195
Herpes simplex contraindication 88594005 DOID:8566
Kidney disease contraindication 90708001 DOID:557
Prolonged QT interval contraindication 111975006
Malignant lymphoma contraindication 118600007 DOID:0060058
Seizure disorder contraindication 128613002
Eczema herpeticum contraindication 186535001 DOID:9123
Toxic nephropathy contraindication 236514003
Post-transplant lymphoproliferative disorder contraindication 254290004
Infectious mononucleosis contraindication 271558008 DOID:8568
Netherton's syndrome contraindication 312514006
Coma contraindication 371632003
Primary malignant neoplasm contraindication 372087000
Neuropathy contraindication 386033004 DOID:870
Breastfeeding (mother) contraindication 413712001
Congenital long QT syndrome contraindication 442917000
Posterior reversible encephalopathy syndrome contraindication 450886002
Tacrolimus Toxicity contraindication
Tremors contraindication
BK Polyomavirus Reactivation Nephropathy contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.4 acidic
pKa2 13.12 acidic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11110081 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11123331 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 12083103 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11110081 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11123331 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 12083103 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 10864199 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11110081 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 11123331 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 12083103 May 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 0.75MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 1MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8664239 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN DE NOVO TRANSPLANT PATIENT
EQ 4MG BASE ENVARSUS XR VELOXIS PHARMS INC N206406 July 10, 2015 RX TABLET, EXTENDED RELEASE ORAL 8685998 Aug. 30, 2028 PROPHYLAXIS OF ORGAN REJECTION IN PATIENTS CONVERTED FROM TACROLIMUS IMMEDIATE-RELEASE FORMULATIONS

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
EQ 0.5MG BASE PROGRAF ASTELLAS N050708 Aug. 24, 1998 RX CAPSULE ORAL July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT
EQ 1MG BASE PROGRAF ASTELLAS N050708 April 8, 1994 RX CAPSULE ORAL July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT
EQ 5MG BASE PROGRAF ASTELLAS N050708 April 8, 1994 RX CAPSULE ORAL July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT
EQ 5MG BASE/ML PROGRAF ASTELLAS N050709 April 8, 1994 RX INJECTABLE INJECTION July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT
EQ 0.2MG BASE/PACKET PROGRAF ASTELLAS N210115 May 24, 2018 RX FOR SUSPENSION ORAL July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT
EQ 1MG BASE/PACKET PROGRAF ASTELLAS N210115 May 24, 2018 RX FOR SUSPENSION ORAL July 16, 2028 FOR PROPHYLAXIS OF ORGAN REJECTION IN ADULT AND PEDIATRIC PATIENTS RECEIVING ALLOGENEIC LUNG TRANSPLANT

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Peptidyl-prolyl cis-trans isomerase FKBP1A Enzyme INHIBITOR Kd 9.40 WOMBAT-PK CHEMBL
Cytochrome P450 3A4 Enzyme IC50 6 DRUG MATRIX
Interleukin-5 Cytokine IC50 10.22 WOMBAT-PK
Interferon gamma Cytokine IC50 10.22 WOMBAT-PK
ATP-binding cassette sub-family G member 2 Transporter IC50 5.48 CHEMBL
Interleukin-2 Cytokine IC50 9.72 WOMBAT-PK
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform Enzyme Ki 7.46 WOMBAT-PK
Serine/threonine-protein kinase mTOR Kinase IC50 9.02 CHEMBL
Peptidyl-prolyl cis-trans isomerase FKBP4 Enzyme Kd 7.64 CHEMBL
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Enzyme Kd 7.70 CHEMBL
Peptidyl-prolyl cis-trans isomerase FKBP1B Enzyme Kd 9.40 CHEMBL
Transient receptor potential cation channel subfamily M member 8 Ion channel ACTIVATOR EC50 4.85 IUPHAR
Peptidyl-prolyl cis-trans isomerase FKBP5 Enzyme Ki 7.10 CHEMBL
Splicing factor 3B subunit 3 Nuclear other IC50 7.96 CHEMBL
Potassium voltage-gated channel subfamily H member 2 Ion channel IC50 6 WOMBAT-PK
Peptidyl-prolyl cis-trans isomerase FKBP10 Enzyme IC50 9.02 WOMBAT-PK

External reference:

IDSource
4020868 VUID
N0000148372 NUI
D00107 KEGG_DRUG
109581-93-3 SECONDARY_CAS_RN
4020868 VANDF
C0085149 UMLSCUI
CHEBI:61049 CHEBI
CHEMBL269732 ChEMBL_ID
CHEMBL3989887 ChEMBL_ID
D016559 MESH_DESCRIPTOR_UI
DB00864 DRUGBANK_ID
6784 IUPHAR_LIGAND_ID
WM0HAQ4WNM UNII
445643 PUBCHEM_CID
235991 RXNORM
133309 MMSL
5539 MMSL
66434 MMSL
d03752 MMSL
004446 NDDF
004447 NDDF
109129008 SNOMEDCT_US
1269093001 SNOMEDCT_US
386975001 SNOMEDCT_US
6878 INN_ID
WM0HAQ4WNM INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0168-0416 OINTMENT 1 mg TOPICAL ANDA 26 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0168-0417 OINTMENT 0.30 mg TOPICAL ANDA 26 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0378-2045 CAPSULE 0.50 mg ORAL ANDA 29 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0378-2046 CAPSULE 1 mg ORAL ANDA 29 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0378-2047 CAPSULE 5 mg ORAL ANDA 29 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-0607 CAPSULE, GELATIN COATED 0.50 mg ORAL NDA 30 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-0617 CAPSULE, GELATIN COATED 1 mg ORAL NDA 30 sections
ASTAGRAF XL HUMAN PRESCRIPTION DRUG LABEL 1 0469-0647 CAPSULE, COATED, EXTENDED RELEASE 0.50 mg ORAL NDA 27 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-0657 CAPSULE, GELATIN COATED 5 mg ORAL NDA 30 sections
ASTAGRAF XL HUMAN PRESCRIPTION DRUG LABEL 1 0469-0677 CAPSULE, COATED, EXTENDED RELEASE 1 mg ORAL NDA 27 sections
ASTAGRAF XL HUMAN PRESCRIPTION DRUG LABEL 1 0469-0687 CAPSULE, COATED, EXTENDED RELEASE 5 mg ORAL NDA 27 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-1230 GRANULE, FOR SUSPENSION 0.20 mg ORAL NDA 30 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-1330 GRANULE, FOR SUSPENSION 1 mg ORAL NDA 30 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 0469-3016 INJECTION, SOLUTION 5 mg INTRAVENOUS NDA 30 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0781-2102 CAPSULE 0.50 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0781-2103 CAPSULE 1 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0781-2104 CAPSULE 5 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0904-6623 CAPSULE 0.50 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0904-6624 CAPSULE 5 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 0904-7097 CAPSULE 1 mg ORAL ANDA 26 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 14789-135 INJECTION 5 mg INTRAVENOUS ANDA 32 sections
tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16714-098 CAPSULE 0.50 mg ORAL ANDA 28 sections
tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16714-099 CAPSULE 1 mg ORAL ANDA 28 sections
tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16714-100 CAPSULE 5 mg ORAL ANDA 28 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16729-041 CAPSULE 0.50 mg ORAL ANDA 29 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16729-042 CAPSULE 1 mg ORAL ANDA 29 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16729-043 CAPSULE 5 mg ORAL ANDA 29 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16729-421 OINTMENT 0.30 mg TOPICAL ANDA 25 sections
Tacrolimus HUMAN PRESCRIPTION DRUG LABEL 1 16729-422 OINTMENT 1 mg TOPICAL ANDA 25 sections
Prograf HUMAN PRESCRIPTION DRUG LABEL 1 21695-170 CAPSULE, GELATIN COATED 1 mg ORAL NDA 24 sections