voclosporin Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4366 515814-01-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ISATX247
  • ISA-247
  • ISA247
  • ISA 247
  • voclosporin
semi-synthetic cyclosporine A analog & calcineurin inhibitor
  • Molecular weight: 1214.65
  • Formula: C63H111N11O12
  • CLOGP: 14.47
  • LIPINSKI: 3
  • HAC: 23
  • HDO: 5
  • TPSA: 278.80
  • ALOGS: -5.48
  • ROTB: 16

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC L04AD03 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
IMMUNOSUPPRESSANTS
IMMUNOSUPPRESSANTS
Calcineurin inhibitors

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Noninfectious Uveitis indication

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D09033 KEGG_DRUG
2PN063X6B1 UNII
8889 INN_ID
DB11693 DRUGBANK_ID
CHEBI:135957 CHEBI
CHEMBL2218919 ChEMBL_ID
6918486 PUBCHEM_CID
C484071 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None