Molfile
Inchi
Smiles
Synonyms:
-
elidel
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pimecrolimus
-
picrolimus
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an ascomycin derivative; mechanism of action involves calcineurin inhibition, blockage of T cell activation, blocking signal transduction pathways in T cells, and inhibition of the synthesis of inflammatory cytokines, specifically Th1- and Th2-type cytokines
- Molecular weight: 810.46
- Formula: C43H68ClNO11
- CLOGP: 7.10
- LIPINSKI: 3
- HAC: 12
- HDO: 2
- TPSA: 158.13
- ALOGS: -5.73
- ROTB: 6
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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