syrosingopine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
derivatives of Rauwolfia alkaloids 2550 84-36-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • syrosingopine
  • methyl carbethoxysyringoyl reserpate
  • singoserp
  • syringopine
  • syrosingopin
  • Molecular weight: 666.72
  • Formula: C35H42N2O11
  • CLOGP: 3.60
  • LIPINSKI: 2
  • HAC: 13
  • HDO: 1
  • TPSA: 144.08
  • ALOGS: -4.83
  • ROTB: 13

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02LA09 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Rauwolfia alkaloids and diuretics in combination

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.2 acidic
pKa2 6.78 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01659 KEGG_DRUG
C0039148 UMLSCUI
CHEBI:32175 CHEBI
CHEMBL1399124 ChEMBL_ID
C084824 MESH_SUPPLEMENTAL_RECORD_UI
849 INN_ID
PPG46JF0EG UNII
6769 PUBCHEM_CID
000649 NDDF
12208001 SNOMEDCT_US

Pharmaceutical products:

None