Stem definition | Drug id | CAS RN |
---|---|---|
serotonin reuptake inhibitors | 2436 | 79617-96-2 |
Dose | Unit | Route |
---|---|---|
50 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 3.80 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.20 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 9.33 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 44 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 30, 1991 | FDA | PFIZER |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Intentional self-injury | 1141.66 | 9.58 | 866 | 207853 | 22246 | 50374159 |
Intentional overdose | 942.68 | 9.58 | 1224 | 207495 | 61280 | 50335125 |
Serotonin syndrome | 808.11 | 9.58 | 729 | 207990 | 23984 | 50372421 |
Suicidal ideation | 728.69 | 9.58 | 1015 | 207704 | 54370 | 50342035 |
Suicide attempt | 713.60 | 9.58 | 970 | 207749 | 50762 | 50345643 |
Drug abuse | 623.54 | 9.58 | 983 | 207736 | 58863 | 50337542 |
Anxiety | 454.19 | 9.58 | 1686 | 207033 | 175920 | 50220485 |
Synovitis | 411.01 | 9.58 | 25 | 208694 | 123840 | 50272565 |
Contraindicated product administered | 390.87 | 9.58 | 71 | 208648 | 148887 | 50247518 |
Drug interaction | 384.36 | 9.58 | 1736 | 206983 | 197885 | 50198520 |
Agitation | 373.01 | 9.58 | 736 | 207983 | 52648 | 50343757 |
Systemic lupus erythematosus | 364.72 | 9.58 | 69 | 208650 | 140553 | 50255852 |
Hand deformity | 359.18 | 9.58 | 12 | 208707 | 100187 | 50296218 |
Drug intolerance | 329.61 | 9.58 | 253 | 208466 | 218851 | 50177554 |
Completed suicide | 320.27 | 9.58 | 1232 | 207487 | 130657 | 50265748 |
Treatment failure | 314.32 | 9.58 | 89 | 208630 | 137548 | 50258857 |
Joint swelling | 305.31 | 9.58 | 337 | 208382 | 244949 | 50151456 |
Tremor | 299.41 | 9.58 | 1098 | 207621 | 113805 | 50282600 |
Glossodynia | 294.81 | 9.58 | 59 | 208660 | 115510 | 50280895 |
Rheumatoid arthritis | 293.18 | 9.58 | 243 | 208476 | 202307 | 50194098 |
Akathisia | 279.28 | 9.58 | 248 | 208471 | 7981 | 50388424 |
Infusion related reaction | 268.96 | 9.58 | 185 | 208534 | 169372 | 50227033 |
Arthropathy | 258.93 | 9.58 | 166 | 208553 | 157740 | 50238665 |
Toxicity to various agents | 255.43 | 9.58 | 1624 | 207095 | 210875 | 50185530 |
Drug ineffective | 253.47 | 9.58 | 2166 | 206553 | 817167 | 49579238 |
Withdrawal syndrome | 248.69 | 9.58 | 334 | 208385 | 17256 | 50379149 |
Depression | 247.80 | 9.58 | 1340 | 207379 | 164083 | 50232322 |
Abnormal behaviour | 230.07 | 9.58 | 341 | 208378 | 19317 | 50377088 |
Alopecia | 228.04 | 9.58 | 414 | 208305 | 244633 | 50151772 |
Pericarditis | 214.05 | 9.58 | 34 | 208685 | 78655 | 50317750 |
Sopor | 213.06 | 9.58 | 331 | 208388 | 19548 | 50376857 |
Hallucination | 207.84 | 9.58 | 538 | 208181 | 46119 | 50350286 |
Panic attack | 204.43 | 9.58 | 320 | 208399 | 19022 | 50377383 |
Swelling | 199.97 | 9.58 | 325 | 208394 | 200547 | 50195858 |
Aggression | 183.66 | 9.58 | 320 | 208399 | 20796 | 50375609 |
Mania | 182.11 | 9.58 | 225 | 208494 | 10691 | 50385714 |
Therapeutic product effect decreased | 177.96 | 9.58 | 179 | 208540 | 135871 | 50260534 |
Bruxism | 177.31 | 9.58 | 126 | 208593 | 2914 | 50393491 |
Overdose | 175.87 | 9.58 | 846 | 207873 | 98881 | 50297524 |
Rash | 173.91 | 9.58 | 1075 | 207644 | 436396 | 49960009 |
Wound | 172.28 | 9.58 | 112 | 208607 | 105682 | 50290723 |
Arthralgia | 166.19 | 9.58 | 1094 | 207625 | 437608 | 49958797 |
Abdominal discomfort | 164.21 | 9.58 | 454 | 208265 | 231187 | 50165218 |
Hallucination, auditory | 162.91 | 9.58 | 211 | 208508 | 10517 | 50385888 |
Hepatic enzyme increased | 162.88 | 9.58 | 196 | 208523 | 137184 | 50259221 |
Somnolence | 157.03 | 9.58 | 1136 | 207583 | 153849 | 50242556 |
Mydriasis | 156.69 | 9.58 | 206 | 208513 | 10421 | 50385984 |
Restlessness | 154.40 | 9.58 | 329 | 208390 | 24844 | 50371561 |
Hyponatraemia | 154.22 | 9.58 | 794 | 207925 | 95345 | 50301060 |
Duodenal ulcer perforation | 148.85 | 9.58 | 10 | 208709 | 45601 | 50350804 |
Rheumatoid factor positive | 146.35 | 9.58 | 17 | 208702 | 49842 | 50346563 |
Off label use | 145.53 | 9.58 | 1255 | 207464 | 473171 | 49923234 |
Paranoia | 145.52 | 9.58 | 196 | 208523 | 10152 | 50386253 |
Helicobacter infection | 143.29 | 9.58 | 18 | 208701 | 49684 | 50346721 |
Nasopharyngitis | 140.54 | 9.58 | 373 | 208346 | 192554 | 50203851 |
Psychotic disorder | 137.16 | 9.58 | 288 | 208431 | 21524 | 50374881 |
Extrapyramidal disorder | 134.61 | 9.58 | 202 | 208517 | 11568 | 50384837 |
Self-injurious ideation | 131.42 | 9.58 | 93 | 208626 | 2136 | 50394269 |
Peripheral swelling | 131.23 | 9.58 | 424 | 208295 | 205512 | 50190893 |
Product use issue | 129.75 | 9.58 | 263 | 208456 | 149212 | 50247193 |
Hypersensitivity | 127.59 | 9.58 | 457 | 208262 | 214704 | 50181701 |
Folliculitis | 126.84 | 9.58 | 9 | 208710 | 39216 | 50357189 |
Drug withdrawal syndrome | 125.10 | 9.58 | 302 | 208417 | 24779 | 50371626 |
Discomfort | 118.76 | 9.58 | 164 | 208555 | 108216 | 50288189 |
Dyskinesia | 118.67 | 9.58 | 316 | 208403 | 27545 | 50368860 |
Disorientation | 117.79 | 9.58 | 368 | 208351 | 35116 | 50361289 |
Anger | 117.67 | 9.58 | 186 | 208533 | 11147 | 50385258 |
Tic | 116.86 | 9.58 | 69 | 208650 | 1148 | 50395257 |
Electrocardiogram QT prolonged | 116.30 | 9.58 | 473 | 208246 | 51413 | 50344992 |
Depressed mood | 114.93 | 9.58 | 355 | 208364 | 33668 | 50362737 |
Insomnia | 113.91 | 9.58 | 1162 | 207557 | 173703 | 50222702 |
Delusion | 111.87 | 9.58 | 175 | 208544 | 10394 | 50386011 |
Crying | 111.82 | 9.58 | 255 | 208464 | 20161 | 50376244 |
Disturbance in attention | 110.59 | 9.58 | 331 | 208388 | 30855 | 50365550 |
Galactorrhoea | 110.32 | 9.58 | 104 | 208615 | 3619 | 50392786 |
Pyrexia | 110.17 | 9.58 | 1020 | 207699 | 379183 | 50017222 |
Confusional state | 109.18 | 9.58 | 1210 | 207509 | 184718 | 50211687 |
Dizziness | 108.83 | 9.58 | 2019 | 206700 | 344350 | 50052055 |
Irritability | 108.75 | 9.58 | 310 | 208409 | 28116 | 50368289 |
Muscle injury | 105.62 | 9.58 | 14 | 208705 | 37097 | 50359308 |
Stomatitis | 105.47 | 9.58 | 159 | 208560 | 101185 | 50295220 |
Pain | 103.61 | 9.58 | 1723 | 206996 | 577180 | 49819225 |
Infection | 102.72 | 9.58 | 367 | 208352 | 172587 | 50223818 |
Seizure | 100.93 | 9.58 | 831 | 207888 | 117043 | 50279362 |
Myoclonus | 100.38 | 9.58 | 199 | 208520 | 14271 | 50382134 |
Homicidal ideation | 100.32 | 9.58 | 71 | 208648 | 1631 | 50394774 |
Apathy | 97.16 | 9.58 | 137 | 208582 | 7411 | 50388994 |
Febrile neutropenia | 96.16 | 9.58 | 159 | 208560 | 97508 | 50298897 |
Feeling abnormal | 95.56 | 9.58 | 862 | 207857 | 124630 | 50271775 |
Lower respiratory tract infection | 93.72 | 9.58 | 155 | 208564 | 95046 | 50301359 |
Thinking abnormal | 92.48 | 9.58 | 152 | 208567 | 9415 | 50386990 |
Muscle rigidity | 92.11 | 9.58 | 154 | 208565 | 9675 | 50386730 |
Nightmare | 88.18 | 9.58 | 201 | 208518 | 15885 | 50380520 |
Malignant neoplasm progression | 86.35 | 9.58 | 92 | 208627 | 68032 | 50328373 |
Inappropriate antidiuretic hormone secretion | 85.51 | 9.58 | 176 | 208543 | 12967 | 50383438 |
Impaired healing | 85.41 | 9.58 | 97 | 208622 | 69689 | 50326716 |
Blister | 85.08 | 9.58 | 138 | 208581 | 85280 | 50311125 |
Sinusitis | 84.24 | 9.58 | 389 | 208330 | 170169 | 50226236 |
Emotional distress | 84.07 | 9.58 | 285 | 208434 | 28378 | 50368027 |
Poisoning deliberate | 83.73 | 9.58 | 131 | 208588 | 7781 | 50388624 |
Psychomotor hyperactivity | 83.55 | 9.58 | 143 | 208576 | 9158 | 50387247 |
Hyperreflexia | 82.97 | 9.58 | 104 | 208615 | 5014 | 50391391 |
Mood swings | 81.60 | 9.58 | 194 | 208525 | 15760 | 50380645 |
Hyperhidrosis | 81.18 | 9.58 | 639 | 208080 | 88787 | 50307618 |
Loss of consciousness | 81.07 | 9.58 | 720 | 207999 | 103633 | 50292772 |
Hallucinations, mixed | 80.71 | 9.58 | 92 | 208627 | 4011 | 50392394 |
C-reactive protein abnormal | 80.33 | 9.58 | 10 | 208709 | 27799 | 50368606 |
Dystonia | 80.31 | 9.58 | 162 | 208557 | 11764 | 50384641 |
Homicide | 79.13 | 9.58 | 36 | 208683 | 336 | 50396069 |
C-reactive protein increased | 78.56 | 9.58 | 95 | 208624 | 66379 | 50330026 |
Product substitution issue | 77.45 | 9.58 | 176 | 208543 | 13881 | 50382524 |
Delirium | 76.13 | 9.58 | 336 | 208383 | 37856 | 50358549 |
Hyperprolactinaemia | 75.78 | 9.58 | 81 | 208638 | 3284 | 50393121 |
Treatment noncompliance | 74.96 | 9.58 | 284 | 208435 | 29866 | 50366539 |
Anorgasmia | 73.87 | 9.58 | 39 | 208680 | 516 | 50395889 |
General physical health deterioration | 73.24 | 9.58 | 320 | 208399 | 142114 | 50254291 |
Suicidal behaviour | 72.63 | 9.58 | 67 | 208652 | 2267 | 50394138 |
Foetal exposure during pregnancy | 72.44 | 9.58 | 263 | 208456 | 27096 | 50369309 |
Neutropenia | 72.15 | 9.58 | 339 | 208380 | 147626 | 50248779 |
Hallucination, visual | 71.54 | 9.58 | 189 | 208530 | 16393 | 50380012 |
Social avoidant behaviour | 71.39 | 9.58 | 72 | 208647 | 2725 | 50393680 |
Mental disorder | 70.16 | 9.58 | 225 | 208494 | 21766 | 50374639 |
Renal impairment | 70.07 | 9.58 | 128 | 208591 | 75533 | 50320872 |
Poisoning | 68.90 | 9.58 | 156 | 208563 | 12273 | 50384132 |
Oromandibular dystonia | 67.45 | 9.58 | 34 | 208685 | 406 | 50395999 |
Infarction | 67.01 | 9.58 | 64 | 208655 | 2264 | 50394141 |
Drug dependence | 66.56 | 9.58 | 206 | 208513 | 19553 | 50376852 |
Abnormal dreams | 66.30 | 9.58 | 130 | 208589 | 9247 | 50387158 |
Libido decreased | 65.91 | 9.58 | 64 | 208655 | 2312 | 50394093 |
Salivary hypersecretion | 65.44 | 9.58 | 106 | 208613 | 6485 | 50389920 |
Neuroleptic malignant syndrome | 65.41 | 9.58 | 143 | 208576 | 10987 | 50385418 |
Muscle twitching | 64.67 | 9.58 | 174 | 208545 | 15257 | 50381148 |
Hypomania | 64.36 | 9.58 | 86 | 208633 | 4419 | 50391986 |
Parkinsonism | 64.19 | 9.58 | 124 | 208595 | 8723 | 50387682 |
Obsessive-compulsive disorder | 64.19 | 9.58 | 74 | 208645 | 3266 | 50393139 |
Tardive dyskinesia | 64.18 | 9.58 | 111 | 208608 | 7168 | 50389237 |
Emotional disorder | 63.89 | 9.58 | 147 | 208572 | 11689 | 50384716 |
Maculopathy | 62.07 | 9.58 | 57 | 208662 | 1917 | 50394488 |
Ill-defined disorder | 61.56 | 9.58 | 81 | 208638 | 54573 | 50341832 |
Formication | 60.57 | 9.58 | 75 | 208644 | 3571 | 50392834 |
Activation syndrome | 60.05 | 9.58 | 25 | 208694 | 184 | 50396221 |
Impulsive behaviour | 59.81 | 9.58 | 49 | 208670 | 1409 | 50394996 |
Product complaint | 59.26 | 9.58 | 140 | 208579 | 11326 | 50385079 |
Dysarthria | 58.59 | 9.58 | 307 | 208412 | 37096 | 50359309 |
Thrombocytopenia | 57.36 | 9.58 | 301 | 208418 | 127372 | 50269033 |
Hip arthroplasty | 57.04 | 9.58 | 27 | 208692 | 30402 | 50366003 |
Bradykinesia | 55.92 | 9.58 | 75 | 208644 | 3868 | 50392537 |
Trismus | 55.82 | 9.58 | 69 | 208650 | 3279 | 50393126 |
Colitis microscopic | 55.63 | 9.58 | 98 | 208621 | 6422 | 50389983 |
Drug screen false positive | 54.95 | 9.58 | 37 | 208682 | 782 | 50395623 |
Agitation neonatal | 54.91 | 9.58 | 31 | 208688 | 472 | 50395933 |
Pancytopenia | 54.85 | 9.58 | 171 | 208548 | 83859 | 50312546 |
Psychomotor retardation | 54.69 | 9.58 | 69 | 208650 | 3349 | 50393056 |
Stiff person syndrome | 54.39 | 9.58 | 24 | 208695 | 207 | 50396198 |
Major depression | 54.31 | 9.58 | 100 | 208619 | 6784 | 50389621 |
Irritable bowel syndrome | 54.18 | 9.58 | 80 | 208639 | 51361 | 50345044 |
Flat affect | 53.83 | 9.58 | 44 | 208675 | 1261 | 50395144 |
Newborn persistent pulmonary hypertension | 53.64 | 9.58 | 21 | 208698 | 129 | 50396276 |
Generalised tonic-clonic seizure | 53.60 | 9.58 | 233 | 208486 | 26077 | 50370328 |
Blood prolactin increased | 53.50 | 9.58 | 65 | 208654 | 3034 | 50393371 |
Gestational diabetes | 53.39 | 9.58 | 104 | 208615 | 7361 | 50389044 |
Amenorrhoea | 53.31 | 9.58 | 112 | 208607 | 8372 | 50388033 |
Gastrointestinal disorder | 53.04 | 9.58 | 205 | 208514 | 94251 | 50302154 |
Knee arthroplasty | 53.02 | 9.58 | 42 | 208677 | 35804 | 50360601 |
Persistent genital arousal disorder | 52.39 | 9.58 | 24 | 208695 | 228 | 50396177 |
Mental impairment | 51.68 | 9.58 | 137 | 208582 | 11907 | 50384498 |
Mucosal inflammation | 51.09 | 9.58 | 54 | 208665 | 40088 | 50356317 |
Bradyphrenia | 50.60 | 9.58 | 91 | 208628 | 6061 | 50390344 |
Yawning | 50.59 | 9.58 | 37 | 208682 | 896 | 50395509 |
Euphoric mood | 49.84 | 9.58 | 72 | 208647 | 3983 | 50392422 |
Mood altered | 48.56 | 9.58 | 139 | 208580 | 12634 | 50383771 |
Negative thoughts | 48.45 | 9.58 | 35 | 208684 | 831 | 50395574 |
Cytomegalovirus infection | 48.29 | 9.58 | 8 | 208711 | 17954 | 50378451 |
Psychotic symptom | 48.19 | 9.58 | 40 | 208679 | 1172 | 50395233 |
Memory impairment | 48.11 | 9.58 | 520 | 208199 | 78840 | 50317565 |
Tachycardia | 47.84 | 9.58 | 625 | 208094 | 99138 | 50297267 |
Death | 47.83 | 9.58 | 1001 | 207718 | 324378 | 50072027 |
Abnormal weight gain | 47.76 | 9.58 | 43 | 208676 | 1409 | 50394996 |
Reversible cerebral vasoconstriction syndrome | 47.71 | 9.58 | 51 | 208668 | 2068 | 50394337 |
Fear | 46.54 | 9.58 | 149 | 208570 | 14400 | 50382005 |
Intrusive thoughts | 46.40 | 9.58 | 20 | 208699 | 162 | 50396243 |
Eye movement disorder | 46.36 | 9.58 | 74 | 208645 | 4471 | 50391934 |
Drug withdrawal syndrome neonatal | 46.27 | 9.58 | 47 | 208672 | 1794 | 50394611 |
Inflammation | 46.11 | 9.58 | 104 | 208615 | 56808 | 50339597 |
Burning mouth syndrome | 45.99 | 9.58 | 26 | 208693 | 397 | 50396008 |
Alcoholism | 45.62 | 9.58 | 44 | 208675 | 1576 | 50394829 |
Depressed level of consciousness | 45.35 | 9.58 | 368 | 208351 | 51585 | 50344820 |
Intentional product use issue | 45.09 | 9.58 | 164 | 208555 | 76754 | 50319651 |
Respiratory arrest | 44.07 | 9.58 | 242 | 208477 | 29767 | 50366638 |
Cardiac failure | 44.00 | 9.58 | 163 | 208556 | 75877 | 50320528 |
Loss of libido | 43.78 | 9.58 | 38 | 208681 | 1185 | 50395220 |
Disease progression | 43.61 | 9.58 | 225 | 208494 | 95641 | 50300764 |
Cholecystitis chronic | 43.55 | 9.58 | 112 | 208607 | 9557 | 50386848 |
Acute kidney injury | 43.15 | 9.58 | 671 | 208048 | 227387 | 50169018 |
Abulia | 43.09 | 9.58 | 25 | 208694 | 402 | 50396003 |
Drug screen positive | 42.68 | 9.58 | 61 | 208658 | 3341 | 50393064 |
Pleurothotonus | 41.75 | 9.58 | 38 | 208681 | 1263 | 50395142 |
Emotional poverty | 41.68 | 9.58 | 22 | 208697 | 291 | 50396114 |
Tension | 41.43 | 9.58 | 54 | 208665 | 2708 | 50393697 |
Flashback | 41.32 | 9.58 | 17 | 208702 | 121 | 50396284 |
Torticollis | 41.25 | 9.58 | 43 | 208676 | 1693 | 50394712 |
Schizophrenia | 41.18 | 9.58 | 93 | 208626 | 7304 | 50389101 |
Fall | 40.75 | 9.58 | 1729 | 206990 | 333203 | 50063202 |
Drowning | 40.66 | 9.58 | 24 | 208695 | 399 | 50396006 |
Amnesia | 40.56 | 9.58 | 306 | 208413 | 41954 | 50354451 |
Musculoskeletal stiffness | 40.02 | 9.58 | 338 | 208381 | 128143 | 50268262 |
Balance disorder | 39.80 | 9.58 | 456 | 208263 | 70134 | 50326271 |
Arthritis | 39.19 | 9.58 | 204 | 208515 | 86517 | 50309888 |
Restless legs syndrome | 38.89 | 9.58 | 149 | 208570 | 15748 | 50380657 |
Injection site pain | 38.80 | 9.58 | 283 | 208436 | 110741 | 50285664 |
Sensation of foreign body | 38.67 | 9.58 | 63 | 208656 | 3873 | 50392532 |
Pruritus | 38.59 | 9.58 | 883 | 207836 | 282685 | 50113720 |
Depersonalisation/derealisation disorder | 38.47 | 9.58 | 35 | 208684 | 1163 | 50395242 |
Cardiac arrest | 38.41 | 9.58 | 520 | 208199 | 83131 | 50313274 |
Catatonia | 38.35 | 9.58 | 61 | 208658 | 3675 | 50392730 |
Depressive symptom | 38.14 | 9.58 | 56 | 208663 | 3144 | 50393261 |
Cycloplegia | 37.88 | 9.58 | 9 | 208710 | 3 | 50396402 |
Therapeutic product effect incomplete | 37.68 | 9.58 | 222 | 208497 | 91293 | 50305112 |
Conjunctival abrasion | 37.45 | 9.58 | 11 | 208708 | 22 | 50396383 |
Vertigo | 37.36 | 9.58 | 352 | 208367 | 51480 | 50344925 |
Speech disorder | 37.33 | 9.58 | 263 | 208456 | 35285 | 50361120 |
Sedation | 37.29 | 9.58 | 235 | 208484 | 30375 | 50366030 |
Musculoskeletal pain | 37.17 | 9.58 | 162 | 208557 | 72015 | 50324390 |
Hypersomnia | 37.03 | 9.58 | 143 | 208576 | 15171 | 50381234 |
Affective disorder | 36.84 | 9.58 | 72 | 208647 | 5109 | 50391296 |
Anhedonia | 36.55 | 9.58 | 104 | 208615 | 9420 | 50386985 |
Psoriatic arthropathy | 36.45 | 9.58 | 88 | 208631 | 46944 | 50349461 |
Retroplacental haematoma | 36.36 | 9.58 | 16 | 208703 | 137 | 50396268 |
Paraesthesia | 35.91 | 9.58 | 696 | 208023 | 119547 | 50276858 |
Tremor neonatal | 35.36 | 9.58 | 14 | 208705 | 89 | 50396316 |
Pneumonia | 35.26 | 9.58 | 1242 | 207477 | 377159 | 50019246 |
Syncope | 34.51 | 9.58 | 607 | 208112 | 102395 | 50294010 |
Pregnancy with implant contraceptive | 34.23 | 9.58 | 42 | 208677 | 1981 | 50394424 |
Intentional product misuse | 34.00 | 9.58 | 318 | 208401 | 46416 | 50349989 |
Cerebral vasoconstriction | 33.86 | 9.58 | 30 | 208689 | 962 | 50395443 |
Anaemia | 33.80 | 9.58 | 788 | 207931 | 251668 | 50144737 |
Sepsis | 33.62 | 9.58 | 368 | 208351 | 132557 | 50263848 |
Eosinophilic pneumonia acute | 33.55 | 9.58 | 19 | 208700 | 291 | 50396114 |
Psychomotor skills impaired | 33.55 | 9.58 | 42 | 208677 | 2022 | 50394383 |
Clonus | 33.38 | 9.58 | 61 | 208658 | 4114 | 50392291 |
Hyponatraemic seizure | 33.31 | 9.58 | 21 | 208698 | 395 | 50396010 |
Hallucination, olfactory | 33.15 | 9.58 | 17 | 208702 | 211 | 50396194 |
Rabbit syndrome | 32.99 | 9.58 | 19 | 208700 | 301 | 50396104 |
Pleural effusion | 32.79 | 9.58 | 199 | 208520 | 81255 | 50315150 |
Palpitations | 32.77 | 9.58 | 560 | 208159 | 93946 | 50302459 |
Pain in extremity | 32.67 | 9.58 | 866 | 207853 | 271999 | 50124406 |
Heavy menstrual bleeding | 31.95 | 9.58 | 138 | 208581 | 15399 | 50381006 |
Disorganised speech | 31.91 | 9.58 | 29 | 208690 | 962 | 50395443 |
Neuropathy peripheral | 31.74 | 9.58 | 251 | 208468 | 96506 | 50299899 |
Uterine perforation | 31.72 | 9.58 | 77 | 208642 | 6338 | 50390067 |
Therapeutic response unexpected | 31.70 | 9.58 | 140 | 208579 | 15775 | 50380630 |
Somatic symptom disorder of pregnancy | 31.66 | 9.58 | 13 | 208706 | 92 | 50396313 |
Septic shock | 31.50 | 9.58 | 125 | 208594 | 57050 | 50339355 |
Rhabdomyolysis | 31.17 | 9.58 | 271 | 208448 | 38756 | 50357649 |
Victim of chemical submission | 30.87 | 9.58 | 17 | 208702 | 246 | 50396159 |
Neonatal asphyxia | 30.82 | 9.58 | 16 | 208703 | 204 | 50396201 |
Tinnitus | 30.64 | 9.58 | 210 | 208509 | 27922 | 50368483 |
Mental status changes | 30.62 | 9.58 | 255 | 208464 | 36017 | 50360388 |
Disturbance in sexual arousal | 30.61 | 9.58 | 12 | 208707 | 74 | 50396331 |
Vision blurred | 30.60 | 9.58 | 475 | 208244 | 78172 | 50318233 |
Schizoaffective disorder bipolar type | 30.41 | 9.58 | 13 | 208706 | 103 | 50396302 |
Bipolar disorder | 30.15 | 9.58 | 78 | 208641 | 6679 | 50389726 |
Conversion disorder | 30.07 | 9.58 | 35 | 208684 | 1561 | 50394844 |
Lethargy | 30.00 | 9.58 | 324 | 208395 | 49108 | 50347297 |
Nystagmus | 29.94 | 9.58 | 69 | 208650 | 5492 | 50390913 |
Bipolar I disorder | 29.79 | 9.58 | 34 | 208685 | 1484 | 50394921 |
Phobia | 29.74 | 9.58 | 18 | 208701 | 314 | 50396091 |
Bradycardia neonatal | 29.71 | 9.58 | 26 | 208693 | 820 | 50395585 |
Bone erosion | 29.71 | 9.58 | 6 | 208713 | 11681 | 50384724 |
Injection site erythema | 29.68 | 9.58 | 184 | 208535 | 74752 | 50321653 |
Neonatal respiratory distress syndrome | 29.56 | 9.58 | 45 | 208674 | 2609 | 50393796 |
Herpes zoster | 29.52 | 9.58 | 171 | 208548 | 70615 | 50325790 |
Central vision loss | 29.51 | 9.58 | 8 | 208711 | 10 | 50396395 |
Poverty of thought content | 29.51 | 9.58 | 8 | 208711 | 10 | 50396395 |
Psychiatric symptom | 29.49 | 9.58 | 61 | 208658 | 4509 | 50391896 |
Foaming at mouth | 29.29 | 9.58 | 29 | 208690 | 1073 | 50395332 |
Platelet count decreased | 29.14 | 9.58 | 270 | 208449 | 100456 | 50295949 |
Pancreatic fibrosis | 29.09 | 9.58 | 12 | 208707 | 86 | 50396319 |
Skin ulcer | 29.05 | 9.58 | 64 | 208655 | 35254 | 50361151 |
Coordination abnormal | 28.95 | 9.58 | 109 | 208610 | 11425 | 50384980 |
Dyspnoea | 28.53 | 9.58 | 1911 | 206808 | 545697 | 49850708 |
Alcohol poisoning | 28.26 | 9.58 | 36 | 208683 | 1764 | 50394641 |
Hyponatraemic syndrome | 28.21 | 9.58 | 21 | 208698 | 523 | 50395882 |
Bone marrow failure | 28.08 | 9.58 | 44 | 208675 | 27580 | 50368825 |
Borderline personality disorder | 27.97 | 9.58 | 23 | 208696 | 665 | 50395740 |
Depression suicidal | 27.92 | 9.58 | 33 | 208686 | 1496 | 50394909 |
Idiopathic intracranial hypertension | 27.84 | 9.58 | 41 | 208678 | 2308 | 50394097 |
Suppressed lactation | 27.75 | 9.58 | 19 | 208700 | 413 | 50395992 |
Cardio-respiratory arrest | 27.68 | 9.58 | 342 | 208377 | 53550 | 50342855 |
Respiratory disorder neonatal | 27.33 | 9.58 | 26 | 208693 | 915 | 50395490 |
Basal cell carcinoma | 26.93 | 9.58 | 34 | 208685 | 23322 | 50373083 |
Violence-related symptom | 26.75 | 9.58 | 18 | 208701 | 380 | 50396025 |
Alcohol abuse | 26.71 | 9.58 | 36 | 208683 | 1865 | 50394540 |
Leukopenia | 26.64 | 9.58 | 166 | 208553 | 67362 | 50329043 |
Hereditary angioedema | 26.56 | 9.58 | 65 | 208654 | 5377 | 50391028 |
Cough | 26.48 | 9.58 | 775 | 207944 | 240489 | 50155916 |
Nervousness | 26.41 | 9.58 | 200 | 208519 | 27451 | 50368954 |
Neutrophil count decreased | 26.40 | 9.58 | 99 | 208620 | 45927 | 50350478 |
Confabulation | 26.39 | 9.58 | 16 | 208703 | 280 | 50396125 |
Urinary incontinence | 26.36 | 9.58 | 203 | 208516 | 28005 | 50368400 |
Upper gastrointestinal haemorrhage | 26.07 | 9.58 | 133 | 208586 | 15902 | 50380503 |
Device dislocation | 25.99 | 9.58 | 165 | 208554 | 21381 | 50375024 |
Hemivertebra | 25.92 | 9.58 | 12 | 208707 | 117 | 50396288 |
Antisocial behaviour | 25.80 | 9.58 | 16 | 208703 | 292 | 50396113 |
Blood creatinine increased | 25.71 | 9.58 | 196 | 208523 | 75964 | 50320441 |
Perinatal depression | 25.45 | 9.58 | 20 | 208699 | 541 | 50395864 |
Somnambulism | 25.31 | 9.58 | 60 | 208659 | 4864 | 50391541 |
Injection site bruising | 25.29 | 9.58 | 73 | 208646 | 36695 | 50359710 |
Maternal drugs affecting foetus | 25.17 | 9.58 | 61 | 208658 | 5016 | 50391389 |
White blood cell count decreased | 25.00 | 9.58 | 335 | 208384 | 116387 | 50280018 |
Pulmonary embolism | 24.93 | 9.58 | 572 | 208147 | 101132 | 50295273 |
Caesarean section | 24.92 | 9.58 | 129 | 208590 | 15510 | 50380895 |
Inappropriate affect | 24.79 | 9.58 | 23 | 208696 | 784 | 50395621 |
Maternal exposure during pregnancy | 24.77 | 9.58 | 487 | 208232 | 159291 | 50237114 |
Food interaction | 24.74 | 9.58 | 21 | 208698 | 635 | 50395770 |
Lung disorder | 24.64 | 9.58 | 98 | 208621 | 44701 | 50351704 |
Device placement issue | 24.57 | 9.58 | 23 | 208696 | 793 | 50395612 |
Fatigue | 24.50 | 9.58 | 2551 | 206168 | 705050 | 49691355 |
Neutropenic sepsis | 24.37 | 9.58 | 14 | 208705 | 14133 | 50382272 |
Hypotonia neonatal | 24.24 | 9.58 | 25 | 208694 | 972 | 50395433 |
Dysphemia | 24.15 | 9.58 | 38 | 208681 | 2268 | 50394137 |
Muscle tightness | 24.05 | 9.58 | 95 | 208624 | 10185 | 50386220 |
Factor XIII deficiency | 23.97 | 9.58 | 10 | 208709 | 74 | 50396331 |
Respiratory tract infection | 23.95 | 9.58 | 61 | 208658 | 31956 | 50364449 |
Mutism | 23.90 | 9.58 | 29 | 208690 | 1352 | 50395053 |
Large for dates baby | 23.88 | 9.58 | 18 | 208701 | 457 | 50395948 |
Intermenstrual bleeding | 23.84 | 9.58 | 72 | 208647 | 6742 | 50389663 |
Osteoporosis | 23.55 | 9.58 | 100 | 208619 | 44779 | 50351626 |
Embedded device | 23.38 | 9.58 | 42 | 208677 | 2795 | 50393610 |
Incoherent | 23.34 | 9.58 | 53 | 208666 | 4177 | 50392228 |
Mobility decreased | 23.26 | 9.58 | 214 | 208505 | 79734 | 50316671 |
Herbal interaction | 23.10 | 9.58 | 10 | 208709 | 82 | 50396323 |
Antipsychotic drug level increased | 23.08 | 9.58 | 44 | 208675 | 3065 | 50393340 |
Tachyphrenia | 22.95 | 9.58 | 27 | 208692 | 1218 | 50395187 |
Haemophagocytic lymphohistiocytosis | 22.86 | 9.58 | 4 | 208715 | 8629 | 50387776 |
Red blood cell sedimentation rate increased | 22.82 | 9.58 | 55 | 208664 | 29361 | 50367044 |
Obsessive thoughts | 22.78 | 9.58 | 18 | 208701 | 491 | 50395914 |
Swollen tongue | 22.44 | 9.58 | 198 | 208521 | 28432 | 50367973 |
Dissociative disorder | 22.24 | 9.58 | 13 | 208706 | 212 | 50396193 |
Abortion missed | 22.21 | 9.58 | 30 | 208689 | 1558 | 50394847 |
Persistent foetal circulation | 22.19 | 9.58 | 13 | 208706 | 213 | 50396192 |
Tuberculosis | 22.12 | 9.58 | 7 | 208712 | 10076 | 50386329 |
Transient psychosis | 21.96 | 9.58 | 8 | 208711 | 39 | 50396366 |
Adrenal insufficiency | 21.94 | 9.58 | 16 | 208703 | 14227 | 50382178 |
Coma | 21.92 | 9.58 | 343 | 208376 | 56536 | 50339869 |
Sleep-related eating disorder | 21.89 | 9.58 | 21 | 208698 | 747 | 50395658 |
Hallucination, gustatory | 21.88 | 9.58 | 9 | 208710 | 64 | 50396341 |
Injection site pruritus | 21.85 | 9.58 | 89 | 208630 | 40322 | 50356083 |
Unresponsive to stimuli | 21.62 | 9.58 | 207 | 208512 | 30402 | 50366003 |
Mitochondrial encephalomyopathy | 21.61 | 9.58 | 7 | 208712 | 22 | 50396383 |
Creatinine renal clearance decreased | 21.57 | 9.58 | 11 | 208708 | 11870 | 50384535 |
Environmental exposure | 21.53 | 9.58 | 9 | 208710 | 67 | 50396338 |
Cold sweat | 21.48 | 9.58 | 94 | 208625 | 10550 | 50385855 |
Soliloquy | 21.41 | 9.58 | 12 | 208707 | 180 | 50396225 |
Rheumatoid nodule | 21.38 | 9.58 | 13 | 208706 | 12722 | 50383683 |
Alcohol intolerance | 21.30 | 9.58 | 9 | 208710 | 69 | 50396336 |
Foreign body in reproductive tract | 21.26 | 9.58 | 17 | 208702 | 472 | 50395933 |
Hypersensitivity pneumonitis | 21.25 | 9.58 | 36 | 208683 | 2286 | 50394119 |
Diplopia | 21.11 | 9.58 | 144 | 208575 | 19116 | 50377289 |
Impaired reasoning | 21.08 | 9.58 | 9 | 208710 | 71 | 50396334 |
Self esteem decreased | 21.02 | 9.58 | 18 | 208701 | 551 | 50395854 |
Drug hypersensitivity | 20.98 | 9.58 | 1250 | 207469 | 249760 | 50146645 |
Amniotic fluid volume increased | 20.81 | 9.58 | 11 | 208708 | 146 | 50396259 |
Neoplasm progression | 20.71 | 9.58 | 57 | 208662 | 29100 | 50367305 |
Judgement impaired | 20.69 | 9.58 | 18 | 208701 | 563 | 50395842 |
Pneumocystis jirovecii pneumonia | 20.67 | 9.58 | 18 | 208701 | 14645 | 50381760 |
Right ventricular hypertrophy | 20.59 | 9.58 | 19 | 208700 | 643 | 50395762 |
Anaphylactic shock | 20.59 | 9.58 | 32 | 208687 | 20123 | 50376282 |
Post-traumatic stress disorder | 20.59 | 9.58 | 51 | 208668 | 4252 | 50392153 |
Parkinsonian gait | 20.58 | 9.58 | 16 | 208703 | 426 | 50395979 |
Urine sodium decreased | 20.55 | 9.58 | 11 | 208708 | 150 | 50396255 |
Injury | 20.39 | 9.58 | 299 | 208420 | 48626 | 50347779 |
Bundle branch block right | 20.09 | 9.58 | 53 | 208666 | 4592 | 50391813 |
Drug eruption | 20.06 | 9.58 | 42 | 208677 | 23564 | 50372841 |
Hypochloraemia | 19.89 | 9.58 | 29 | 208690 | 1618 | 50394787 |
Stress | 19.83 | 9.58 | 322 | 208397 | 53471 | 50342934 |
Erythromelalgia | 19.72 | 9.58 | 10 | 208709 | 121 | 50396284 |
Thermal burn | 19.70 | 9.58 | 54 | 208665 | 4787 | 50391618 |
Brain injury | 19.61 | 9.58 | 62 | 208657 | 5952 | 50390453 |
Tongue spasm | 19.56 | 9.58 | 8 | 208711 | 56 | 50396349 |
Congenital brain damage | 19.55 | 9.58 | 5 | 208714 | 4 | 50396401 |
Exposure during pregnancy | 19.55 | 9.58 | 645 | 208074 | 120370 | 50276035 |
Flight of ideas | 19.54 | 9.58 | 14 | 208705 | 328 | 50396077 |
Drug resistance | 19.54 | 9.58 | 30 | 208689 | 18959 | 50377446 |
Complication of device insertion | 19.44 | 9.58 | 62 | 208657 | 5979 | 50390426 |
Small for dates baby | 19.43 | 9.58 | 44 | 208675 | 3461 | 50392944 |
Haematoma muscle | 19.06 | 9.58 | 19 | 208700 | 709 | 50395696 |
Femur-fibula-ulna complex | 19.03 | 9.58 | 5 | 208714 | 5 | 50396400 |
Tearfulness | 19.03 | 9.58 | 45 | 208674 | 3642 | 50392763 |
Sexual dysfunction | 19.01 | 9.58 | 42 | 208677 | 3250 | 50393155 |
Gallbladder cholesterolosis | 18.97 | 9.58 | 19 | 208700 | 713 | 50395692 |
Panic disorder | 18.86 | 9.58 | 34 | 208685 | 2269 | 50394136 |
Cataract | 18.80 | 9.58 | 116 | 208603 | 47184 | 50349221 |
Delusion of reference | 18.74 | 9.58 | 9 | 208710 | 96 | 50396309 |
Miosis | 18.73 | 9.58 | 63 | 208656 | 6247 | 50390158 |
Menstruation irregular | 18.71 | 9.58 | 62 | 208657 | 6100 | 50390305 |
Polymenorrhoea | 18.69 | 9.58 | 23 | 208696 | 1088 | 50395317 |
Posture abnormal | 18.61 | 9.58 | 32 | 208687 | 2057 | 50394348 |
Affect lability | 18.56 | 9.58 | 80 | 208639 | 8918 | 50387487 |
Multiple sclerosis relapse | 18.47 | 9.58 | 264 | 208455 | 42700 | 50353705 |
Long QT syndrome | 18.44 | 9.58 | 39 | 208680 | 2928 | 50393477 |
Negative symptoms in schizophrenia | 18.27 | 9.58 | 9 | 208710 | 102 | 50396303 |
Maternal exposure during breast feeding | 18.21 | 9.58 | 41 | 208678 | 3213 | 50393192 |
Metabolic syndrome | 18.16 | 9.58 | 25 | 208694 | 1322 | 50395083 |
Neonatal seizure | 18.16 | 9.58 | 14 | 208705 | 368 | 50396037 |
Ophthalmic vein thrombosis | 18.14 | 9.58 | 10 | 208709 | 145 | 50396260 |
Target skin lesion | 18.04 | 9.58 | 9 | 208710 | 105 | 50396300 |
Catastrophic reaction | 18.03 | 9.58 | 6 | 208713 | 21 | 50396384 |
Intracranial meningioma malignant | 17.98 | 9.58 | 4 | 208715 | 0 | 50396405 |
Slow response to stimuli | 17.97 | 9.58 | 20 | 208699 | 849 | 50395556 |
Renal dysplasia | 17.96 | 9.58 | 10 | 208709 | 148 | 50396257 |
Ductus arteriosus premature closure | 17.84 | 9.58 | 13 | 208706 | 313 | 50396092 |
Athetosis | 17.82 | 9.58 | 6 | 208713 | 22 | 50396383 |
Palmar-plantar erythrodysaesthesia syndrome | 17.72 | 9.58 | 35 | 208684 | 20063 | 50376342 |
Dissociation | 17.72 | 9.58 | 33 | 208686 | 2258 | 50394147 |
Lack of spontaneous speech | 17.67 | 9.58 | 10 | 208709 | 153 | 50396252 |
Suicide threat | 17.61 | 9.58 | 6 | 208713 | 23 | 50396382 |
Persistent depressive disorder | 17.56 | 9.58 | 20 | 208699 | 871 | 50395534 |
Hyperkalaemia | 17.56 | 9.58 | 121 | 208598 | 47968 | 50348437 |
Infantile vomiting | 17.53 | 9.58 | 9 | 208710 | 112 | 50396293 |
Urinary retention | 17.46 | 9.58 | 175 | 208544 | 26015 | 50370390 |
Congenital skin dimples | 17.46 | 9.58 | 9 | 208710 | 113 | 50396292 |
Tenosynovitis | 17.44 | 9.58 | 11 | 208708 | 10554 | 50385851 |
Water intoxication | 17.40 | 9.58 | 14 | 208705 | 392 | 50396013 |
Vanishing bile duct syndrome | 17.37 | 9.58 | 17 | 208702 | 620 | 50395785 |
Injection site swelling | 17.36 | 9.58 | 101 | 208618 | 41672 | 50354733 |
Personality disorder | 17.36 | 9.58 | 48 | 208671 | 4276 | 50392129 |
Photophobia | 17.33 | 9.58 | 113 | 208606 | 14774 | 50381631 |
Urine chloride decreased | 17.28 | 9.58 | 8 | 208711 | 78 | 50396327 |
Product taste abnormal | 17.24 | 9.58 | 28 | 208691 | 1717 | 50394688 |
Heat stroke | 17.24 | 9.58 | 17 | 208702 | 626 | 50395779 |
Bronchopulmonary aspergillosis | 17.14 | 9.58 | 5 | 208714 | 7587 | 50388818 |
Somatic delusion | 17.13 | 9.58 | 16 | 208703 | 550 | 50395855 |
CYP3A4 polymorphism | 17.11 | 9.58 | 8 | 208711 | 80 | 50396325 |
Hypercalcaemia | 17.08 | 9.58 | 45 | 208674 | 23307 | 50373098 |
Alcohol use | 17.04 | 9.58 | 30 | 208689 | 1965 | 50394440 |
Hepatic function abnormal | 17.03 | 9.58 | 73 | 208646 | 32608 | 50363797 |
Dopamine dysregulation syndrome | 16.96 | 9.58 | 10 | 208709 | 166 | 50396239 |
Therapy non-responder | 16.89 | 9.58 | 132 | 208587 | 50890 | 50345515 |
Ataxia | 16.89 | 9.58 | 106 | 208613 | 13680 | 50382725 |
Illness anxiety disorder | 16.86 | 9.58 | 9 | 208710 | 122 | 50396283 |
Vomiting | 16.76 | 9.58 | 2157 | 206562 | 458601 | 49937804 |
Libido disorder | 16.64 | 9.58 | 7 | 208712 | 53 | 50396352 |
Blood creatine phosphokinase increased | 16.54 | 9.58 | 174 | 208545 | 26193 | 50370212 |
Action tremor | 16.43 | 9.58 | 12 | 208707 | 290 | 50396115 |
Phalangeal hypoplasia | 16.41 | 9.58 | 5 | 208714 | 12 | 50396393 |
Myelosuppression | 16.30 | 9.58 | 19 | 208700 | 13498 | 50382907 |
Tongue discolouration | 16.27 | 9.58 | 36 | 208683 | 2788 | 50393617 |
Postural orthostatic tachycardia syndrome | 16.22 | 9.58 | 19 | 208700 | 853 | 50395552 |
Pelvic pain | 16.17 | 9.58 | 90 | 208629 | 11123 | 50385282 |
Logorrhoea | 16.16 | 9.58 | 32 | 208687 | 2292 | 50394113 |
Lipidosis | 16.12 | 9.58 | 5 | 208714 | 13 | 50396392 |
Alkalosis hypochloraemic | 16.12 | 9.58 | 9 | 208710 | 134 | 50396271 |
Visceral congestion | 16.08 | 9.58 | 12 | 208707 | 300 | 50396105 |
Partner stress | 16.08 | 9.58 | 12 | 208707 | 300 | 50396105 |
Delusional disorder, unspecified type | 16.04 | 9.58 | 13 | 208706 | 368 | 50396037 |
Myocardial fibrosis | 15.95 | 9.58 | 17 | 208702 | 687 | 50395718 |
Gallbladder injury | 15.94 | 9.58 | 23 | 208696 | 1271 | 50395134 |
Hypertonia | 15.85 | 9.58 | 44 | 208675 | 3929 | 50392476 |
Ascites | 15.83 | 9.58 | 85 | 208634 | 35776 | 50360629 |
Substance abuse | 15.79 | 9.58 | 45 | 208674 | 4079 | 50392326 |
Morbid thoughts | 15.79 | 9.58 | 15 | 208704 | 527 | 50395878 |
Sluggishness | 15.79 | 9.58 | 47 | 208672 | 4366 | 50392039 |
Drug dose titration not performed | 15.77 | 9.58 | 14 | 208705 | 450 | 50395955 |
Glucose tolerance impaired in pregnancy | 15.75 | 9.58 | 4 | 208715 | 3 | 50396402 |
Petit mal epilepsy | 15.75 | 9.58 | 39 | 208680 | 3250 | 50393155 |
Drug reaction with eosinophilia and systemic symptoms | 15.75 | 9.58 | 62 | 208657 | 28362 | 50368043 |
Diaphragmatic rupture | 15.72 | 9.58 | 11 | 208708 | 248 | 50396157 |
Dry mouth | 15.69 | 9.58 | 322 | 208397 | 55856 | 50340549 |
Economic problem | 15.69 | 9.58 | 28 | 208691 | 1854 | 50394551 |
Muscle contracture | 15.67 | 9.58 | 22 | 208697 | 1185 | 50395220 |
Electrocardiogram T wave abnormal | 15.64 | 9.58 | 31 | 208688 | 2222 | 50394183 |
Physical assault | 15.60 | 9.58 | 19 | 208700 | 889 | 50395516 |
Oral discomfort | 15.57 | 9.58 | 70 | 208649 | 7947 | 50388458 |
Social anxiety disorder | 15.46 | 9.58 | 13 | 208706 | 388 | 50396017 |
Peritonitis | 15.43 | 9.58 | 25 | 208694 | 15461 | 50380944 |
Suspiciousness | 15.42 | 9.58 | 12 | 208707 | 320 | 50396085 |
Teratoma benign | 15.33 | 9.58 | 7 | 208712 | 66 | 50396339 |
Weight increased | 15.30 | 9.58 | 997 | 207722 | 200894 | 50195511 |
Metastases to bone | 15.30 | 9.58 | 32 | 208687 | 17963 | 50378442 |
Distractibility | 15.29 | 9.58 | 13 | 208706 | 394 | 50396011 |
Device expulsion | 15.27 | 9.58 | 184 | 208535 | 28638 | 50367767 |
Biliary dyskinesia | 15.25 | 9.58 | 33 | 208686 | 2517 | 50393888 |
Compulsions | 15.24 | 9.58 | 10 | 208709 | 202 | 50396203 |
Nephropathy toxic | 15.24 | 9.58 | 7 | 208712 | 8022 | 50388383 |
Localised infection | 15.15 | 9.58 | 54 | 208665 | 25431 | 50370974 |
Snoring | 15.03 | 9.58 | 39 | 208680 | 3345 | 50393060 |
Diverticulitis | 15.01 | 9.58 | 78 | 208641 | 33104 | 50363301 |
Screaming | 15.00 | 9.58 | 36 | 208683 | 2942 | 50393463 |
Derealisation | 14.99 | 9.58 | 20 | 208699 | 1026 | 50395379 |
Hypokalaemia | 14.99 | 9.58 | 472 | 208247 | 87520 | 50308885 |
Osteonecrosis of jaw | 14.97 | 9.58 | 76 | 208643 | 32450 | 50363955 |
Hypoaesthesia eye | 14.97 | 9.58 | 7 | 208712 | 70 | 50396335 |
Postural tremor | 14.86 | 9.58 | 10 | 208709 | 211 | 50396194 |
Marital problem | 14.82 | 9.58 | 9 | 208710 | 158 | 50396247 |
Lip blister | 14.78 | 9.58 | 28 | 208691 | 1941 | 50394464 |
Thrombotic microangiopathy | 14.72 | 9.58 | 9 | 208710 | 8782 | 50387623 |
Attention-seeking behaviour | 14.71 | 9.58 | 7 | 208712 | 73 | 50396332 |
Atrioventricular dissociation | 14.66 | 9.58 | 10 | 208709 | 216 | 50396189 |
Grip strength decreased | 14.66 | 9.58 | 17 | 208702 | 12104 | 50384301 |
Serum serotonin increased | 14.62 | 9.58 | 9 | 208710 | 162 | 50396243 |
Complication of device removal | 14.57 | 9.58 | 44 | 208675 | 4120 | 50392285 |
Infantile apnoea | 14.57 | 9.58 | 18 | 208701 | 855 | 50395550 |
Transplant rejection | 14.54 | 9.58 | 11 | 208708 | 9598 | 50386807 |
Spleen congestion | 14.51 | 9.58 | 8 | 208711 | 116 | 50396289 |
May-Thurner syndrome | 14.51 | 9.58 | 5 | 208714 | 20 | 50396385 |
Fear of weight gain | 14.51 | 9.58 | 5 | 208714 | 20 | 50396385 |
Postpartum haemorrhage | 14.50 | 9.58 | 26 | 208693 | 1728 | 50394677 |
Drug tolerance decreased | 14.49 | 9.58 | 10 | 208709 | 9150 | 50387255 |
Joint hyperextension | 14.44 | 9.58 | 11 | 208708 | 284 | 50396121 |
Accommodation disorder | 14.42 | 9.58 | 12 | 208707 | 353 | 50396052 |
Acute myeloid leukaemia | 14.40 | 9.58 | 25 | 208694 | 15049 | 50381356 |
Collagen-vascular disease | 14.39 | 9.58 | 7 | 208712 | 77 | 50396328 |
Hypercapnic coma | 14.34 | 9.58 | 9 | 208710 | 168 | 50396237 |
Asocial behaviour | 14.32 | 9.58 | 5 | 208714 | 21 | 50396384 |
Pulmonary infarction | 14.31 | 9.58 | 31 | 208688 | 2367 | 50394038 |
Gross motor delay | 14.22 | 9.58 | 8 | 208711 | 121 | 50396284 |
Feeling guilty | 14.18 | 9.58 | 14 | 208705 | 516 | 50395889 |
Leukaemoid reaction | 14.06 | 9.58 | 9 | 208710 | 174 | 50396231 |
Cognitive disorder | 14.05 | 9.58 | 258 | 208461 | 43865 | 50352540 |
Pre-eclampsia | 13.98 | 9.58 | 68 | 208651 | 7976 | 50388429 |
Loss of personal independence in daily activities | 13.94 | 9.58 | 204 | 208515 | 69846 | 50326559 |
Tunnel vision | 13.94 | 9.58 | 16 | 208703 | 703 | 50395702 |
Wrong patient | 13.93 | 9.58 | 7 | 208712 | 83 | 50396322 |
Chorea | 13.92 | 9.58 | 22 | 208697 | 1318 | 50395087 |
Metastases to lung | 13.83 | 9.58 | 15 | 208704 | 11005 | 50385400 |
Blood pressure diastolic abnormal | 13.80 | 9.58 | 11 | 208708 | 9350 | 50387055 |
Female orgasmic disorder | 13.77 | 9.58 | 6 | 208713 | 50 | 50396355 |
Menopausal disorder | 13.77 | 9.58 | 6 | 208713 | 50 | 50396355 |
Drug monitoring procedure incorrectly performed | 13.77 | 9.58 | 8 | 208711 | 129 | 50396276 |
Rectal cancer metastatic | 13.75 | 9.58 | 10 | 208709 | 240 | 50396165 |
Psychogenic seizure | 13.75 | 9.58 | 24 | 208695 | 1561 | 50394844 |
Morning sickness | 13.72 | 9.58 | 15 | 208704 | 624 | 50395781 |
Neoplasm malignant | 13.61 | 9.58 | 51 | 208668 | 23664 | 50372741 |
Blood calcium decreased | 13.60 | 9.58 | 42 | 208677 | 20664 | 50375741 |
Dysphoria | 13.58 | 9.58 | 47 | 208672 | 4727 | 50391678 |
Neonatal tachypnoea | 13.57 | 9.58 | 6 | 208713 | 52 | 50396353 |
Cardiotoxicity | 13.53 | 9.58 | 6 | 208713 | 7021 | 50389384 |
COVID-19 | 13.52 | 9.58 | 125 | 208594 | 46537 | 50349868 |
Erythema | 13.49 | 9.58 | 481 | 208238 | 145933 | 50250472 |
Postictal headache | 13.49 | 9.58 | 3 | 208716 | 0 | 50396405 |
Anaplastic large cell lymphoma T- and null-cell types stage IV | 13.49 | 9.58 | 3 | 208716 | 0 | 50396405 |
Analgesic drug level increased | 13.47 | 9.58 | 25 | 208694 | 1706 | 50394699 |
Vasodilation procedure | 13.46 | 9.58 | 5 | 208714 | 26 | 50396379 |
Foetal death | 13.40 | 9.58 | 68 | 208651 | 8112 | 50388293 |
Opisthotonus | 13.38 | 9.58 | 11 | 208708 | 318 | 50396087 |
Multiple sclerosis | 13.22 | 9.58 | 136 | 208583 | 20357 | 50376048 |
Hypokinesia | 13.18 | 9.58 | 91 | 208628 | 12126 | 50384279 |
Impulse-control disorder | 13.14 | 9.58 | 15 | 208704 | 655 | 50395750 |
Congenital tricuspid valve incompetence | 13.10 | 9.58 | 7 | 208712 | 95 | 50396310 |
Laryngomalacia | 13.10 | 9.58 | 6 | 208713 | 57 | 50396348 |
Product odour abnormal | 13.06 | 9.58 | 19 | 208700 | 1058 | 50395347 |
Decreased activity | 13.00 | 9.58 | 49 | 208670 | 5138 | 50391267 |
Myoclonic epilepsy | 13.00 | 9.58 | 18 | 208701 | 957 | 50395448 |
Urinary hesitation | 13.00 | 9.58 | 27 | 208692 | 2002 | 50394403 |
Gambling disorder | 12.96 | 9.58 | 20 | 208699 | 1174 | 50395231 |
Decreased interest | 12.92 | 9.58 | 34 | 208685 | 2942 | 50393463 |
Belligerence | 12.90 | 9.58 | 8 | 208711 | 146 | 50396259 |
Alice in wonderland syndrome | 12.87 | 9.58 | 5 | 208714 | 30 | 50396375 |
Purple glove syndrome | 12.82 | 9.58 | 9 | 208710 | 204 | 50396201 |
Panic reaction | 12.76 | 9.58 | 38 | 208681 | 3531 | 50392874 |
Seizure like phenomena | 12.68 | 9.58 | 18 | 208701 | 980 | 50395425 |
Gynaecomastia | 12.67 | 9.58 | 8 | 208711 | 151 | 50396254 |
Gaze palsy | 12.64 | 9.58 | 21 | 208698 | 1312 | 50395093 |
Gait deviation | 12.58 | 9.58 | 6 | 208713 | 63 | 50396342 |
Abnormal uterine bleeding | 12.56 | 9.58 | 20 | 208699 | 1206 | 50395199 |
Panniculitis | 12.52 | 9.58 | 10 | 208709 | 8493 | 50387912 |
Serositis | 12.51 | 9.58 | 14 | 208705 | 598 | 50395807 |
Death of relative | 12.41 | 9.58 | 9 | 208710 | 215 | 50396190 |
Disinhibition | 12.40 | 9.58 | 16 | 208703 | 794 | 50395611 |
Haemoglobin decreased | 12.39 | 9.58 | 415 | 208304 | 126801 | 50269604 |
Pathogen resistance | 12.39 | 9.58 | 4 | 208715 | 5685 | 50390720 |
Reduced facial expression | 12.38 | 9.58 | 23 | 208696 | 1571 | 50394834 |
Delusional perception | 12.38 | 9.58 | 9 | 208710 | 216 | 50396189 |
Product communication issue | 12.36 | 9.58 | 11 | 208708 | 355 | 50396050 |
Subchorionic haemorrhage | 12.35 | 9.58 | 8 | 208711 | 158 | 50396247 |
Trance | 12.34 | 9.58 | 5 | 208714 | 34 | 50396371 |
CSF glucose decreased | 12.33 | 9.58 | 6 | 208713 | 66 | 50396339 |
Blood parathyroid hormone decreased | 12.31 | 9.58 | 7 | 208712 | 7107 | 50389298 |
Oral herpes | 12.26 | 9.58 | 44 | 208675 | 20681 | 50375724 |
Negativism | 12.25 | 9.58 | 11 | 208708 | 359 | 50396046 |
Exposure via breast milk | 12.24 | 9.58 | 23 | 208696 | 1585 | 50394820 |
Neurological examination abnormal | 12.16 | 9.58 | 9 | 208710 | 222 | 50396183 |
Overweight | 12.14 | 9.58 | 34 | 208685 | 3052 | 50393353 |
Proteinuria | 12.12 | 9.58 | 32 | 208687 | 16565 | 50379840 |
Communication disorder | 12.11 | 9.58 | 28 | 208691 | 2233 | 50394172 |
Altered state of consciousness | 12.10 | 9.58 | 141 | 208578 | 21769 | 50374636 |
Large intestine polyp | 12.05 | 9.58 | 61 | 208658 | 7271 | 50389134 |
Reflexes abnormal | 12.02 | 9.58 | 13 | 208706 | 534 | 50395871 |
Temporomandibular joint syndrome | 12.01 | 9.58 | 37 | 208682 | 3502 | 50392903 |
Nausea | 11.94 | 9.58 | 3175 | 205544 | 702223 | 49694182 |
Hyperthermia | 11.93 | 9.58 | 63 | 208656 | 7633 | 50388772 |
Ulcer | 11.88 | 9.58 | 43 | 208676 | 20157 | 50376248 |
Atrial fibrillation | 11.86 | 9.58 | 324 | 208395 | 101421 | 50294984 |
Attention deficit hyperactivity disorder | 11.84 | 9.58 | 29 | 208690 | 2400 | 50394005 |
Unintended pregnancy | 11.81 | 9.58 | 46 | 208673 | 4900 | 50391505 |
Eosinophilic pneumonia | 11.80 | 9.58 | 25 | 208694 | 1879 | 50394526 |
Glomerulonephritis minimal lesion | 11.79 | 9.58 | 9 | 208710 | 233 | 50396172 |
Right ventricular dilatation | 11.79 | 9.58 | 17 | 208702 | 939 | 50395466 |
Ear infection | 11.77 | 9.58 | 61 | 208658 | 25909 | 50370496 |
Presyncope | 11.75 | 9.58 | 152 | 208567 | 24046 | 50372359 |
Trichotillomania | 11.72 | 9.58 | 7 | 208712 | 119 | 50396286 |
Head injury | 11.72 | 9.58 | 151 | 208568 | 23869 | 50372536 |
Dyspnoea exertional | 11.71 | 9.58 | 145 | 208574 | 51088 | 50345317 |
Blood pressure fluctuation | 11.71 | 9.58 | 93 | 208626 | 35730 | 50360675 |
Metastases to liver | 11.69 | 9.58 | 43 | 208676 | 20061 | 50376344 |
Pseudomonas infection | 11.65 | 9.58 | 13 | 208706 | 9417 | 50386988 |
Hypoosmolar state | 11.64 | 9.58 | 8 | 208711 | 175 | 50396230 |
Anticholinergic syndrome | 11.63 | 9.58 | 24 | 208695 | 1771 | 50394634 |
Staphylococcal scalded skin syndrome | 11.62 | 9.58 | 7 | 208712 | 121 | 50396284 |
Tendonitis | 11.61 | 9.58 | 33 | 208686 | 16672 | 50379733 |
Serum serotonin decreased | 11.61 | 9.58 | 4 | 208715 | 16 | 50396389 |
Crime | 11.61 | 9.58 | 4 | 208715 | 16 | 50396389 |
Granulocytopenia neonatal | 11.61 | 9.58 | 4 | 208715 | 16 | 50396389 |
Interstitial lung disease | 11.60 | 9.58 | 152 | 208567 | 53024 | 50343381 |
Amnestic disorder | 11.60 | 9.58 | 10 | 208709 | 309 | 50396096 |
Menopause | 11.58 | 9.58 | 28 | 208691 | 2299 | 50394106 |
Blood prolactin decreased | 11.55 | 9.58 | 5 | 208714 | 41 | 50396364 |
Meconium in amniotic fluid | 11.53 | 9.58 | 9 | 208710 | 241 | 50396164 |
Heat exhaustion | 11.53 | 9.58 | 6 | 208713 | 77 | 50396328 |
Narcotic bowel syndrome | 11.52 | 9.58 | 7 | 208712 | 123 | 50396282 |
Adverse event | 11.52 | 9.58 | 120 | 208599 | 43643 | 50352762 |
Aplastic anaemia | 11.42 | 9.58 | 9 | 208710 | 7694 | 50388711 |
Boredom | 11.42 | 9.58 | 3 | 208716 | 3 | 50396402 |
Postmortem blood drug level increased | 11.36 | 9.58 | 13 | 208706 | 569 | 50395836 |
Heart rate decreased | 11.36 | 9.58 | 96 | 208623 | 36401 | 50360004 |
Merycism | 11.33 | 9.58 | 8 | 208711 | 183 | 50396222 |
Autoimmune myositis | 11.32 | 9.58 | 6 | 208713 | 80 | 50396325 |
Antidepressant discontinuation syndrome | 11.24 | 9.58 | 4 | 208715 | 18 | 50396387 |
Obsessive-compulsive personality disorder | 11.24 | 9.58 | 4 | 208715 | 18 | 50396387 |
Shared psychotic disorder | 11.24 | 9.58 | 4 | 208715 | 18 | 50396387 |
Febrile bone marrow aplasia | 11.23 | 9.58 | 6 | 208713 | 6305 | 50390100 |
Breast discomfort | 11.22 | 9.58 | 11 | 208708 | 402 | 50396003 |
Skin reaction | 11.22 | 9.58 | 19 | 208700 | 11549 | 50384856 |
Congenital hydronephrosis | 11.20 | 9.58 | 11 | 208708 | 403 | 50396002 |
Bursitis | 11.20 | 9.58 | 50 | 208669 | 22085 | 50374320 |
Myelodysplastic syndrome | 11.19 | 9.58 | 29 | 208690 | 15103 | 50381302 |
Polymenorrhagia | 11.15 | 9.58 | 5 | 208714 | 45 | 50396360 |
Orgasm abnormal | 11.13 | 9.58 | 6 | 208713 | 83 | 50396322 |
Dyspraxia | 11.13 | 9.58 | 9 | 208710 | 254 | 50396151 |
Ankylosing spondylitis | 11.10 | 9.58 | 8 | 208711 | 7157 | 50389248 |
Coma scale abnormal | 11.09 | 9.58 | 44 | 208675 | 4727 | 50391678 |
Disseminated intravascular coagulation | 11.08 | 9.58 | 35 | 208684 | 17100 | 50379305 |
Drug-device interaction | 11.07 | 9.58 | 6 | 208713 | 84 | 50396321 |
Therapeutic response decreased | 11.05 | 9.58 | 133 | 208586 | 47098 | 50349307 |
Cholelithiasis | 11.05 | 9.58 | 219 | 208500 | 37754 | 50358651 |
Enuresis | 11.01 | 9.58 | 26 | 208693 | 2103 | 50394302 |
Fluid retention | 10.97 | 9.58 | 145 | 208574 | 50504 | 50345901 |
Genital hypoaesthesia | 10.96 | 9.58 | 3 | 208716 | 4 | 50396401 |
Gastrostomy tube site complication | 10.96 | 9.58 | 3 | 208716 | 4 | 50396401 |
Adverse drug reaction | 10.92 | 9.58 | 161 | 208558 | 55061 | 50341344 |
Dependence | 10.91 | 9.58 | 24 | 208695 | 1851 | 50394554 |
Chronic kidney disease | 10.90 | 9.58 | 108 | 208611 | 39663 | 50356742 |
Hypotonia | 10.89 | 9.58 | 64 | 208655 | 8070 | 50388335 |
Faeces discoloured | 10.88 | 9.58 | 108 | 208611 | 16016 | 50380389 |
Phalangeal agenesis | 10.87 | 9.58 | 5 | 208714 | 48 | 50396357 |
Stupor | 10.83 | 9.58 | 36 | 208683 | 3547 | 50392858 |
Ventricular septal defect | 10.82 | 9.58 | 39 | 208680 | 4002 | 50392403 |
Feeling of despair | 10.82 | 9.58 | 25 | 208694 | 1993 | 50394412 |
Hyperuricaemia | 10.72 | 9.58 | 3 | 208716 | 4677 | 50391728 |
Lactate pyruvate ratio increased | 10.71 | 9.58 | 6 | 208713 | 90 | 50396315 |
Metastases to lymph nodes | 10.68 | 9.58 | 8 | 208711 | 7016 | 50389389 |
Pelvic inflammatory disease | 10.64 | 9.58 | 21 | 208698 | 1501 | 50394904 |
Tubulointerstitial nephritis | 10.61 | 9.58 | 30 | 208689 | 15181 | 50381224 |
Tumour lysis syndrome | 10.59 | 9.58 | 9 | 208710 | 7412 | 50388993 |
Hostility | 10.59 | 9.58 | 23 | 208696 | 1759 | 50394646 |
Coprolalia | 10.58 | 9.58 | 4 | 208715 | 22 | 50396383 |
Suspected suicide | 10.57 | 9.58 | 47 | 208672 | 5310 | 50391095 |
Fear of injection | 10.57 | 9.58 | 6 | 208713 | 6097 | 50390308 |
Cytokine release syndrome | 10.56 | 9.58 | 12 | 208707 | 8622 | 50387783 |
Gamma-glutamyltransferase abnormal | 10.52 | 9.58 | 8 | 208711 | 206 | 50396199 |
Muscle contractions involuntary | 10.51 | 9.58 | 24 | 208695 | 1898 | 50394507 |
Labour complication | 10.48 | 9.58 | 6 | 208713 | 94 | 50396311 |
Breast enlargement | 10.47 | 9.58 | 20 | 208699 | 1395 | 50395010 |
Deprescribing error | 10.44 | 9.58 | 4 | 208715 | 23 | 50396382 |
Sciatica | 10.40 | 9.58 | 49 | 208670 | 21333 | 50375072 |
Paralysis recurrent laryngeal nerve | 10.36 | 9.58 | 5 | 208714 | 54 | 50396351 |
Second primary malignancy | 10.35 | 9.58 | 8 | 208711 | 6906 | 50389499 |
Genital rash | 10.33 | 9.58 | 11 | 208708 | 444 | 50395961 |
Pulmonary toxicity | 10.32 | 9.58 | 5 | 208714 | 5557 | 50390848 |
Aphasia | 10.29 | 9.58 | 170 | 208549 | 28324 | 50368081 |
Pancreatic enzymes decreased | 10.21 | 9.58 | 3 | 208716 | 6 | 50396399 |
Bladder cyst | 10.21 | 9.58 | 3 | 208716 | 6 | 50396399 |
Cardio-respiratory distress | 10.19 | 9.58 | 7 | 208712 | 153 | 50396252 |
Exposure via ingestion | 10.17 | 9.58 | 30 | 208689 | 2773 | 50393632 |
Fungal infection | 10.16 | 9.58 | 77 | 208642 | 29888 | 50366517 |
Mesenteric panniculitis | 10.15 | 9.58 | 6 | 208713 | 100 | 50396305 |
Implant site irritation | 10.15 | 9.58 | 7 | 208712 | 154 | 50396251 |
Cardiac septal defect | 10.15 | 9.58 | 9 | 208710 | 289 | 50396116 |
Infantile haemangioma | 10.12 | 9.58 | 5 | 208714 | 57 | 50396348 |
Renal failure | 10.12 | 9.58 | 349 | 208370 | 106284 | 50290121 |
Neonatal disorder | 10.05 | 9.58 | 12 | 208707 | 550 | 50395855 |
Blood citric acid increased | 9.97 | 9.58 | 5 | 208714 | 59 | 50396346 |
Oral candidiasis | 9.95 | 9.58 | 36 | 208683 | 16879 | 50379526 |
Death neonatal | 9.95 | 9.58 | 8 | 208711 | 224 | 50396181 |
Hospitalisation | 9.94 | 9.58 | 209 | 208510 | 67728 | 50328677 |
Dissociative amnesia | 9.90 | 9.58 | 4 | 208715 | 27 | 50396378 |
Urticaria | 9.90 | 9.58 | 435 | 208284 | 129126 | 50267279 |
Cytopenia | 9.88 | 9.58 | 13 | 208706 | 8762 | 50387643 |
Psychotic behaviour | 9.86 | 9.58 | 12 | 208707 | 561 | 50395844 |
Polydipsia psychogenic | 9.83 | 9.58 | 5 | 208714 | 61 | 50396344 |
Dependent personality disorder | 9.83 | 9.58 | 5 | 208714 | 61 | 50396344 |
Anal incontinence | 9.81 | 9.58 | 81 | 208638 | 11409 | 50384996 |
Femur fracture | 9.75 | 9.58 | 103 | 208616 | 37361 | 50359044 |
Aphthous ulcer | 9.74 | 9.58 | 18 | 208701 | 10579 | 50385826 |
Rash maculo-papular | 9.74 | 9.58 | 67 | 208652 | 26574 | 50369831 |
Blood test abnormal | 9.73 | 9.58 | 20 | 208699 | 11299 | 50385106 |
Cellulitis | 9.73 | 9.58 | 220 | 208499 | 70578 | 50325827 |
Polyarthritis | 9.71 | 9.58 | 11 | 208708 | 7916 | 50388489 |
Granuloma skin | 9.68 | 9.58 | 6 | 208713 | 5812 | 50390593 |
Hypertonia neonatal | 9.59 | 9.58 | 8 | 208711 | 236 | 50396169 |
Impaired driving ability | 9.59 | 9.58 | 37 | 208682 | 3924 | 50392481 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Depression | 763.64 | 10.27 | 1197 | 102962 | 83950 | 29386418 |
Serotonin syndrome | 677.07 | 10.27 | 532 | 103627 | 16980 | 29453388 |
Suicidal ideation | 521.48 | 10.27 | 627 | 103532 | 34089 | 29436279 |
Drug interaction | 493.40 | 10.27 | 1670 | 102489 | 195715 | 29274653 |
Intentional self-injury | 410.69 | 10.27 | 345 | 103814 | 12116 | 29458252 |
Suicide attempt | 290.50 | 10.27 | 469 | 103690 | 33641 | 29436727 |
Intentional overdose | 287.13 | 10.27 | 499 | 103660 | 38029 | 29432339 |
Completed suicide | 277.17 | 10.27 | 821 | 103338 | 89425 | 29380943 |
Anxiety | 261.55 | 10.27 | 776 | 103383 | 84589 | 29385779 |
Drug abuse | 221.16 | 10.27 | 701 | 103458 | 79182 | 29391186 |
Agitation | 196.26 | 10.27 | 506 | 103653 | 50798 | 29419570 |
Tremor | 185.23 | 10.27 | 625 | 103534 | 72913 | 29397455 |
Foetal exposure during pregnancy | 174.15 | 10.27 | 375 | 103784 | 33492 | 29436876 |
Pyrexia | 171.39 | 10.27 | 486 | 103673 | 287136 | 29183232 |
Aggression | 169.70 | 10.27 | 382 | 103777 | 35159 | 29435209 |
Irritability | 167.68 | 10.27 | 289 | 103870 | 21863 | 29448505 |
Agitation neonatal | 154.04 | 10.27 | 75 | 104084 | 981 | 29469387 |
Somnolence | 142.72 | 10.27 | 682 | 103477 | 93273 | 29377095 |
Maternal exposure during pregnancy | 141.70 | 10.27 | 117 | 104042 | 4006 | 29466362 |
Atrial septal defect | 127.88 | 10.27 | 138 | 104021 | 6651 | 29463717 |
Priapism | 125.12 | 10.27 | 113 | 104046 | 4375 | 29465993 |
Respiratory disorder neonatal | 122.15 | 10.27 | 71 | 104088 | 1354 | 29469014 |
Overdose | 121.62 | 10.27 | 580 | 103579 | 79239 | 29391129 |
Paranoia | 120.55 | 10.27 | 161 | 103998 | 9716 | 29460652 |
Dyskinesia | 114.62 | 10.27 | 232 | 103927 | 19829 | 29450539 |
Acute kidney injury | 113.38 | 10.27 | 515 | 103644 | 264752 | 29205616 |
Parkinsonism | 111.67 | 10.27 | 133 | 104026 | 7145 | 29463223 |
Toxicity to various agents | 111.03 | 10.27 | 1014 | 103145 | 172647 | 29297721 |
Sopor | 110.77 | 10.27 | 163 | 103996 | 10771 | 29459597 |
Febrile neutropenia | 109.26 | 10.27 | 141 | 104018 | 112099 | 29358269 |
Confusional state | 106.58 | 10.27 | 793 | 103366 | 127084 | 29343284 |
Drug withdrawal syndrome neonatal | 105.68 | 10.27 | 91 | 104068 | 3304 | 29467064 |
Obsessive-compulsive disorder | 104.21 | 10.27 | 103 | 104056 | 4473 | 29465895 |
Pneumonia | 98.65 | 10.27 | 692 | 103467 | 319480 | 29150888 |
Sexual dysfunction | 97.13 | 10.27 | 111 | 104048 | 5703 | 29464665 |
Anger | 97.11 | 10.27 | 153 | 104006 | 10737 | 29459631 |
Hallucination, auditory | 95.72 | 10.27 | 142 | 104017 | 9451 | 29460917 |
Blepharospasm | 94.26 | 10.27 | 54 | 104105 | 1001 | 29469367 |
Erectile dysfunction | 92.06 | 10.27 | 199 | 103960 | 17810 | 29452558 |
Withdrawal syndrome | 91.94 | 10.27 | 150 | 104009 | 10842 | 29459526 |
Delusion | 91.04 | 10.27 | 151 | 104008 | 11065 | 29459303 |
Drug withdrawal syndrome | 88.83 | 10.27 | 196 | 103963 | 17788 | 29452580 |
Extrapyramidal disorder | 88.16 | 10.27 | 146 | 104013 | 10685 | 29459683 |
Akathisia | 87.07 | 10.27 | 113 | 104046 | 6629 | 29463739 |
Exposure during pregnancy | 85.90 | 10.27 | 127 | 104032 | 8427 | 29461941 |
Loss of libido | 84.90 | 10.27 | 68 | 104091 | 2228 | 29468140 |
Malignant neoplasm progression | 84.78 | 10.27 | 81 | 104078 | 73778 | 29396590 |
Loss of personal independence in daily activities | 84.22 | 10.27 | 238 | 103921 | 25202 | 29445166 |
Off label use | 84.08 | 10.27 | 668 | 103491 | 300132 | 29170236 |
Restlessness | 83.14 | 10.27 | 217 | 103942 | 21928 | 29448440 |
Psychotic disorder | 81.12 | 10.27 | 204 | 103955 | 20150 | 29450218 |
Anaemia | 81.10 | 10.27 | 398 | 103761 | 200553 | 29269815 |
Sepsis | 80.40 | 10.27 | 247 | 103912 | 142435 | 29327933 |
Dystonia | 78.79 | 10.27 | 131 | 104028 | 9618 | 29460750 |
Insomnia | 78.79 | 10.27 | 559 | 103600 | 88202 | 29382166 |
Pancytopenia | 76.33 | 10.27 | 109 | 104050 | 83059 | 29387309 |
Catatonia | 75.82 | 10.27 | 86 | 104073 | 4382 | 29465986 |
Homicidal ideation | 75.22 | 10.27 | 66 | 104093 | 2458 | 29467910 |
Renal impairment | 74.24 | 10.27 | 107 | 104052 | 81226 | 29389142 |
Thrombocytopenia | 74.11 | 10.27 | 236 | 103923 | 134587 | 29335781 |
Mania | 73.51 | 10.27 | 119 | 104040 | 8544 | 29461824 |
Hallucination | 73.25 | 10.27 | 332 | 103827 | 44380 | 29425988 |
Intrusive thoughts | 72.67 | 10.27 | 29 | 104130 | 226 | 29470142 |
Derealisation | 72.29 | 10.27 | 37 | 104122 | 542 | 29469826 |
Tachyphrenia | 69.15 | 10.27 | 46 | 104113 | 1123 | 29469245 |
Hypomania | 69.12 | 10.27 | 59 | 104100 | 2116 | 29468252 |
Neutropenia | 68.64 | 10.27 | 236 | 103923 | 131475 | 29338893 |
Abnormal behaviour | 67.60 | 10.27 | 207 | 103952 | 22920 | 29447448 |
Obsessive thoughts | 66.97 | 10.27 | 36 | 104123 | 586 | 29469782 |
Sedation | 65.79 | 10.27 | 171 | 103988 | 17234 | 29453134 |
Mood swings | 63.44 | 10.27 | 101 | 104058 | 7150 | 29463218 |
Neuroleptic malignant syndrome | 62.42 | 10.27 | 160 | 103999 | 15988 | 29454380 |
Hypertonia neonatal | 60.13 | 10.27 | 29 | 104130 | 371 | 29469997 |
Feeling jittery | 60.08 | 10.27 | 69 | 104090 | 3564 | 29466804 |
Bradykinesia | 59.60 | 10.27 | 67 | 104092 | 3380 | 29466988 |
Major depression | 58.69 | 10.27 | 70 | 104089 | 3765 | 29466603 |
Amnesia | 58.28 | 10.27 | 194 | 103965 | 22449 | 29447919 |
Bradyphrenia | 56.56 | 10.27 | 72 | 104087 | 4142 | 29466226 |
Colitis microscopic | 56.39 | 10.27 | 48 | 104111 | 1715 | 29468653 |
Cytomegalovirus infection | 55.19 | 10.27 | 8 | 104151 | 23207 | 29447161 |
Nightmare | 53.65 | 10.27 | 122 | 104037 | 11295 | 29459073 |
Treatment noncompliance | 53.22 | 10.27 | 197 | 103962 | 24030 | 29446338 |
Rash | 53.13 | 10.27 | 421 | 103738 | 189398 | 29280970 |
Hyperhidrosis | 52.95 | 10.27 | 399 | 103760 | 64141 | 29406227 |
Large for dates baby | 52.70 | 10.27 | 35 | 104124 | 852 | 29469516 |
Patent ductus arteriosus | 52.68 | 10.27 | 60 | 104099 | 3071 | 29467297 |
Interstitial lung disease | 52.58 | 10.27 | 76 | 104083 | 57642 | 29412726 |
Septic shock | 52.57 | 10.27 | 87 | 104072 | 62473 | 29407895 |
Neuropathy peripheral | 52.38 | 10.27 | 107 | 104052 | 70920 | 29399448 |
Disturbance in attention | 52.01 | 10.27 | 180 | 103979 | 21244 | 29449124 |
Disease progression | 51.86 | 10.27 | 134 | 104025 | 81782 | 29388586 |
Hallucination, visual | 51.18 | 10.27 | 142 | 104017 | 14873 | 29455495 |
Pleural effusion | 50.79 | 10.27 | 111 | 104048 | 71797 | 29398571 |
Fall | 50.71 | 10.27 | 891 | 103268 | 176287 | 29294081 |
Genital hypoaesthesia | 49.82 | 10.27 | 21 | 104138 | 191 | 29470177 |
Neonatal respiratory distress syndrome | 49.42 | 10.27 | 64 | 104095 | 3746 | 29466622 |
Seizure | 49.22 | 10.27 | 523 | 103636 | 92600 | 29377768 |
Homicide | 48.90 | 10.27 | 34 | 104125 | 894 | 29469474 |
Social avoidant behaviour | 48.86 | 10.27 | 56 | 104103 | 2886 | 29467482 |
Tic | 48.80 | 10.27 | 45 | 104114 | 1790 | 29468578 |
Apathy | 48.64 | 10.27 | 82 | 104077 | 6089 | 29464279 |
Bruxism | 48.30 | 10.27 | 42 | 104117 | 1545 | 29468823 |
Thinking abnormal | 47.28 | 10.27 | 74 | 104085 | 5162 | 29465206 |
General physical health deterioration | 46.62 | 10.27 | 195 | 103964 | 102662 | 29367706 |
Maternal exposure during breast feeding | 46.59 | 10.27 | 40 | 104119 | 1446 | 29468922 |
Dyspnoea | 45.86 | 10.27 | 843 | 103316 | 325889 | 29144479 |
Blood prolactin increased | 45.49 | 10.27 | 40 | 104119 | 1494 | 29468874 |
Infusion related reaction | 44.89 | 10.27 | 53 | 104106 | 43833 | 29426535 |
Cogwheel rigidity | 44.23 | 10.27 | 36 | 104123 | 1207 | 29469161 |
Cardiac failure | 44.07 | 10.27 | 138 | 104021 | 79149 | 29391219 |
Ventricular septal defect | 43.78 | 10.27 | 58 | 104101 | 3471 | 29466897 |
Restless legs syndrome | 43.78 | 10.27 | 84 | 104075 | 6900 | 29463468 |
Haemangioma congenital | 43.14 | 10.27 | 25 | 104134 | 474 | 29469894 |
Oromandibular dystonia | 41.74 | 10.27 | 24 | 104135 | 448 | 29469920 |
Depressed mood | 41.50 | 10.27 | 140 | 104019 | 16308 | 29454060 |
Panic attack | 41.40 | 10.27 | 91 | 104068 | 8235 | 29462133 |
Hyponatraemia | 41.09 | 10.27 | 391 | 103768 | 67242 | 29403126 |
Antidepressant drug level increased | 40.78 | 10.27 | 15 | 104144 | 91 | 29470277 |
Resting tremor | 40.71 | 10.27 | 26 | 104133 | 591 | 29469777 |
Bone marrow failure | 40.68 | 10.27 | 23 | 104136 | 27426 | 29442942 |
Sleep disorder | 40.61 | 10.27 | 182 | 103977 | 24204 | 29446164 |
Platelet count decreased | 40.59 | 10.27 | 210 | 103949 | 104462 | 29365906 |
Renal failure | 40.03 | 10.27 | 249 | 103910 | 118350 | 29352018 |
Psychomotor hyperactivity | 39.97 | 10.27 | 89 | 104070 | 8124 | 29462244 |
Feeling abnormal | 39.92 | 10.27 | 328 | 103831 | 54117 | 29416251 |
Product substitution issue | 39.80 | 10.27 | 95 | 104064 | 9077 | 29461291 |
Hyperkalaemia | 39.17 | 10.27 | 100 | 104059 | 61292 | 29409076 |
Bipolar disorder | 39.11 | 10.27 | 53 | 104106 | 3242 | 29467126 |
Muscle twitching | 39.09 | 10.27 | 87 | 104072 | 7939 | 29462429 |
Anorgasmia | 38.62 | 10.27 | 25 | 104134 | 582 | 29469786 |
Oesophageal pain | 38.15 | 10.27 | 27 | 104132 | 731 | 29469637 |
Libido decreased | 37.78 | 10.27 | 60 | 104099 | 4238 | 29466130 |
Ascites | 37.69 | 10.27 | 44 | 104115 | 36575 | 29433793 |
Apgar score low | 37.33 | 10.27 | 28 | 104131 | 831 | 29469537 |
Pneumocystis jirovecii pneumonia | 37.18 | 10.27 | 7 | 104152 | 16772 | 29453596 |
Speech disorder | 35.83 | 10.27 | 171 | 103988 | 23345 | 29447023 |
Arthralgia | 35.70 | 10.27 | 317 | 103842 | 139300 | 29331068 |
Ejaculation failure | 35.58 | 10.27 | 26 | 104133 | 741 | 29469627 |
Antipsychotic drug level increased | 35.26 | 10.27 | 50 | 104109 | 3193 | 29467175 |
Muscle rigidity | 35.09 | 10.27 | 92 | 104067 | 9319 | 29461049 |
Foaming at mouth | 34.97 | 10.27 | 25 | 104134 | 688 | 29469680 |
Diarrhoea | 34.90 | 10.27 | 899 | 103260 | 331799 | 29138569 |
Premature ejaculation | 34.77 | 10.27 | 14 | 104145 | 112 | 29470256 |
Morose | 34.68 | 10.27 | 8 | 104151 | 3 | 29470365 |
Pressure of speech | 34.51 | 10.27 | 21 | 104138 | 437 | 29469931 |
Hepatic function abnormal | 34.48 | 10.27 | 53 | 104106 | 39206 | 29431162 |
Erythema | 34.45 | 10.27 | 143 | 104016 | 75463 | 29394905 |
Infantile apnoea | 34.41 | 10.27 | 27 | 104132 | 858 | 29469510 |
Small for dates baby | 34.30 | 10.27 | 52 | 104107 | 3527 | 29466841 |
Anhedonia | 33.90 | 10.27 | 77 | 104082 | 7123 | 29463245 |
Ideas of reference | 33.83 | 10.27 | 11 | 104148 | 43 | 29470325 |
Mucosal inflammation | 33.56 | 10.27 | 37 | 104122 | 31558 | 29438810 |
Dysphoria | 33.36 | 10.27 | 39 | 104120 | 2053 | 29468315 |
Semen discolouration | 33.10 | 10.27 | 9 | 104150 | 15 | 29470353 |
Loss of consciousness | 32.83 | 10.27 | 402 | 103757 | 73654 | 29396714 |
Stomatitis | 32.69 | 10.27 | 50 | 104109 | 37063 | 29433305 |
Persecutory delusion | 32.63 | 10.27 | 39 | 104120 | 2102 | 29468266 |
Blood creatine phosphokinase increased | 32.60 | 10.27 | 250 | 103909 | 40394 | 29429974 |
Middle insomnia | 32.57 | 10.27 | 66 | 104093 | 5642 | 29464726 |
Depersonalisation/derealisation disorder | 32.30 | 10.27 | 22 | 104137 | 559 | 29469809 |
Affective disorder | 32.23 | 10.27 | 47 | 104112 | 3079 | 29467289 |
Parkinsonism hyperpyrexia syndrome | 32.19 | 10.27 | 12 | 104147 | 76 | 29470292 |
Schizophrenia | 31.79 | 10.27 | 71 | 104088 | 6494 | 29463874 |
Male sexual dysfunction | 31.77 | 10.27 | 16 | 104143 | 226 | 29470142 |
Rheumatoid arthritis | 31.64 | 10.27 | 40 | 104119 | 32112 | 29438256 |
Persistent depressive disorder | 31.50 | 10.27 | 17 | 104142 | 279 | 29470089 |
Acute psychosis | 31.26 | 10.27 | 34 | 104125 | 1653 | 29468715 |
Delusion of replacement | 31.06 | 10.27 | 13 | 104146 | 116 | 29470252 |
Meconium aspiration syndrome | 30.97 | 10.27 | 10 | 104149 | 38 | 29470330 |
Bradycardia neonatal | 30.90 | 10.27 | 26 | 104133 | 914 | 29469454 |
C-reactive protein increased | 30.69 | 10.27 | 69 | 104090 | 44194 | 29426174 |
Blood creatinine increased | 30.64 | 10.27 | 175 | 103984 | 84927 | 29385441 |
Dissociation | 30.63 | 10.27 | 28 | 104131 | 1101 | 29469267 |
Death | 30.60 | 10.27 | 945 | 103214 | 341139 | 29129229 |
Personality change | 30.58 | 10.27 | 57 | 104102 | 4581 | 29465787 |
Tremor neonatal | 30.57 | 10.27 | 18 | 104141 | 352 | 29470016 |
Tumour lysis syndrome | 30.32 | 10.27 | 6 | 104153 | 13878 | 29456490 |
Electrocardiogram QT prolonged | 29.95 | 10.27 | 224 | 103935 | 35913 | 29434455 |
Nasopharyngitis | 29.64 | 10.27 | 109 | 104050 | 59556 | 29410812 |
Drug reaction with eosinophilia and systemic symptoms | 29.49 | 10.27 | 33 | 104126 | 27959 | 29442409 |
Torticollis | 29.40 | 10.27 | 27 | 104132 | 1068 | 29469300 |
Drug screen positive | 29.28 | 10.27 | 50 | 104109 | 3751 | 29466617 |
Muscle strain | 29.25 | 10.27 | 48 | 104111 | 3485 | 29466883 |
White blood cell count decreased | 29.16 | 10.27 | 173 | 103986 | 83189 | 29387179 |
Generalised tonic-clonic seizure | 29.03 | 10.27 | 139 | 104020 | 19000 | 29451368 |
Tearfulness | 28.63 | 10.27 | 32 | 104127 | 1604 | 29468764 |
Hyporesponsive to stimuli | 28.60 | 10.27 | 25 | 104134 | 926 | 29469442 |
Mental disorder | 28.39 | 10.27 | 105 | 104054 | 12800 | 29457568 |
Myoclonus | 28.21 | 10.27 | 107 | 104052 | 13202 | 29457166 |
Dementia with Lewy bodies | 28.18 | 10.27 | 21 | 104138 | 617 | 29469751 |
Platelet aggregation abnormal | 28.16 | 10.27 | 8 | 104151 | 17 | 29470351 |
Head discomfort | 28.14 | 10.27 | 45 | 104114 | 3197 | 29467171 |
Lymphadenopathy | 28.10 | 10.27 | 28 | 104131 | 25021 | 29445347 |
Overweight | 28.09 | 10.27 | 30 | 104129 | 1428 | 29468940 |
Drug dependence | 28.03 | 10.27 | 147 | 104012 | 20834 | 29449534 |
Neonatal respiratory acidosis | 28.00 | 10.27 | 10 | 104149 | 55 | 29470313 |
Left ventricular false tendon | 27.91 | 10.27 | 6 | 104153 | 0 | 29470368 |
Neonatal behavioural syndrome | 27.83 | 10.27 | 12 | 104147 | 116 | 29470252 |
Negativism | 27.76 | 10.27 | 17 | 104142 | 358 | 29470010 |
Prescribed overdose | 27.53 | 10.27 | 80 | 104079 | 8603 | 29461765 |
Grandiosity | 27.48 | 10.27 | 16 | 104143 | 306 | 29470062 |
Exposure via breast milk | 27.44 | 10.27 | 32 | 104127 | 1680 | 29468688 |
Alcoholism | 27.42 | 10.27 | 40 | 104119 | 2621 | 29467747 |
Gastrointestinal motility disorder | 27.41 | 10.27 | 36 | 104123 | 2136 | 29468232 |
Bipolar I disorder | 27.41 | 10.27 | 22 | 104137 | 723 | 29469645 |
Urticaria | 27.05 | 10.27 | 100 | 104059 | 54560 | 29415808 |
Basal cell carcinoma | 26.78 | 10.27 | 13 | 104146 | 16897 | 29453471 |
Tardive dyskinesia | 26.74 | 10.27 | 58 | 104101 | 5200 | 29465168 |
Neonatal respiratory arrest | 26.72 | 10.27 | 8 | 104151 | 22 | 29470346 |
Persistent foetal circulation | 26.55 | 10.27 | 16 | 104143 | 327 | 29470041 |
Agitated depression | 26.48 | 10.27 | 14 | 104145 | 220 | 29470148 |
Pneumonitis | 26.45 | 10.27 | 36 | 104123 | 28008 | 29442360 |
Suicidal behaviour | 26.15 | 10.27 | 28 | 104131 | 1337 | 29469031 |
Prostate cancer | 25.91 | 10.27 | 31 | 104128 | 25496 | 29444872 |
Maternal drugs affecting foetus | 25.86 | 10.27 | 48 | 104111 | 3845 | 29466523 |
Dystonic tremor | 25.79 | 10.27 | 13 | 104146 | 184 | 29470184 |
Impulsive behaviour | 25.76 | 10.27 | 33 | 104126 | 1910 | 29468458 |
Phospholipidosis | 25.58 | 10.27 | 9 | 104150 | 47 | 29470321 |
Anorectal discomfort | 25.52 | 10.27 | 30 | 104129 | 1589 | 29468779 |
Generalised anxiety disorder | 25.34 | 10.27 | 20 | 104139 | 641 | 29469727 |
Oedema peripheral | 25.20 | 10.27 | 238 | 103921 | 103319 | 29367049 |
Self esteem decreased | 25.06 | 10.27 | 18 | 104141 | 499 | 29469869 |
Neonatal respiratory distress | 25.03 | 10.27 | 18 | 104141 | 500 | 29469868 |
Trismus | 24.93 | 10.27 | 36 | 104123 | 2337 | 29468031 |
Myelodysplastic syndrome | 24.84 | 10.27 | 16 | 104143 | 17778 | 29452590 |
Leukopenia | 24.77 | 10.27 | 105 | 104054 | 55098 | 29415270 |
Mydriasis | 24.25 | 10.27 | 61 | 104098 | 6024 | 29464344 |
Macrophages increased | 24.24 | 10.27 | 12 | 104147 | 163 | 29470205 |
Depressive symptom | 24.10 | 10.27 | 30 | 104129 | 1687 | 29468681 |
Neutrophil count decreased | 24.07 | 10.27 | 76 | 104083 | 43491 | 29426877 |
Orthostatic hypotension | 23.95 | 10.27 | 149 | 104010 | 22480 | 29447888 |
Haemoglobin decreased | 23.91 | 10.27 | 255 | 103904 | 108120 | 29362248 |
Radiologically isolated syndrome | 23.78 | 10.27 | 6 | 104153 | 6 | 29470362 |
Unmasking of previously unidentified disease | 23.77 | 10.27 | 20 | 104139 | 703 | 29469665 |
Multiple organ dysfunction syndrome | 23.68 | 10.27 | 128 | 104031 | 62988 | 29407380 |
Graft versus host disease | 23.64 | 10.27 | 3 | 104156 | 9625 | 29460743 |
Balance disorder | 23.41 | 10.27 | 212 | 103947 | 35958 | 29434410 |
Disorientation | 23.36 | 10.27 | 181 | 103978 | 29334 | 29441034 |
Myelosuppression | 23.35 | 10.27 | 7 | 104152 | 12220 | 29458148 |
Neonatal anoxia | 23.26 | 10.27 | 5 | 104154 | 0 | 29470368 |
Drug resistance | 23.12 | 10.27 | 25 | 104134 | 21515 | 29448853 |
Maternal exposure timing unspecified | 22.81 | 10.27 | 15 | 104144 | 359 | 29470009 |
Newborn persistent pulmonary hypertension | 22.72 | 10.27 | 10 | 104149 | 102 | 29470266 |
Inflammation | 22.65 | 10.27 | 28 | 104131 | 22700 | 29447668 |
Urinary hesitation | 22.42 | 10.27 | 33 | 104126 | 2180 | 29468188 |
Dermatillomania | 22.25 | 10.27 | 8 | 104151 | 45 | 29470323 |
Treatment failure | 22.17 | 10.27 | 62 | 104097 | 36877 | 29433491 |
Haemophagocytic lymphohistiocytosis | 21.99 | 10.27 | 5 | 104154 | 10499 | 29459869 |
Negative thoughts | 21.98 | 10.27 | 18 | 104141 | 609 | 29469759 |
Bronchopulmonary aspergillosis | 21.94 | 10.27 | 8 | 104151 | 12336 | 29458032 |
Weight decrease neonatal | 21.89 | 10.27 | 14 | 104145 | 319 | 29470049 |
Post concussion syndrome | 21.83 | 10.27 | 10 | 104149 | 113 | 29470255 |
Prader-Willi syndrome | 21.70 | 10.27 | 6 | 104153 | 11 | 29470357 |
Haemorrhagic hepatic cyst | 21.70 | 10.27 | 6 | 104153 | 11 | 29470357 |
Inappropriate antidiuretic hormone secretion | 21.63 | 10.27 | 86 | 104073 | 10846 | 29459522 |
Tongue biting | 21.51 | 10.27 | 19 | 104140 | 714 | 29469654 |
Alcohol interaction | 21.41 | 10.27 | 36 | 104123 | 2667 | 29467701 |
Excessive masturbation | 21.34 | 10.27 | 9 | 104150 | 82 | 29470286 |
Hypotonia neonatal | 21.28 | 10.27 | 24 | 104135 | 1215 | 29469153 |
Orgasm abnormal | 21.08 | 10.27 | 10 | 104149 | 123 | 29470245 |
Reflux laryngitis | 21.04 | 10.27 | 6 | 104153 | 13 | 29470355 |
Rapid eye movements sleep abnormal | 20.97 | 10.27 | 11 | 104148 | 170 | 29470198 |
Attention deficit hyperactivity disorder | 20.95 | 10.27 | 32 | 104127 | 2185 | 29468183 |
Pulmonary artery stenosis | 20.92 | 10.27 | 12 | 104147 | 223 | 29470145 |
Cytokine release syndrome | 20.91 | 10.27 | 10 | 104149 | 13109 | 29457259 |
Peripheral swelling | 20.87 | 10.27 | 135 | 104024 | 63604 | 29406764 |
Cognitive disorder | 20.81 | 10.27 | 148 | 104011 | 23351 | 29447017 |
Oesophageal ulcer haemorrhage | 20.74 | 10.27 | 11 | 104148 | 174 | 29470194 |
Social anxiety disorder | 20.73 | 10.27 | 12 | 104147 | 227 | 29470141 |
Sedation complication | 20.61 | 10.27 | 24 | 104135 | 1258 | 29469110 |
Parasomnia | 20.58 | 10.27 | 14 | 104145 | 355 | 29470013 |
Lung disorder | 20.50 | 10.27 | 48 | 104111 | 30314 | 29440054 |
Atrial fibrillation | 20.42 | 10.27 | 256 | 103903 | 105390 | 29364978 |
Hypertonia | 20.35 | 10.27 | 43 | 104116 | 3786 | 29466582 |
Product complaint | 20.31 | 10.27 | 53 | 104106 | 5352 | 29465016 |
Infection | 20.15 | 10.27 | 173 | 103986 | 76578 | 29393790 |
Product use in unapproved indication | 20.15 | 10.27 | 202 | 103957 | 86673 | 29383695 |
Acute respiratory distress syndrome | 20.10 | 10.27 | 31 | 104128 | 22904 | 29447464 |
Hepatic enzyme increased | 20.08 | 10.27 | 57 | 104102 | 33742 | 29436626 |
Transplant rejection | 20.08 | 10.27 | 4 | 104155 | 9208 | 29461160 |
Hepatotoxicity | 20.01 | 10.27 | 20 | 104139 | 17847 | 29452521 |
Muscle tightness | 19.99 | 10.27 | 46 | 104113 | 4292 | 29466076 |
Male orgasmic disorder | 19.86 | 10.27 | 9 | 104150 | 99 | 29470269 |
Tongue injury | 19.86 | 10.27 | 9 | 104150 | 99 | 29470269 |
Implant site extravasation | 19.81 | 10.27 | 14 | 104145 | 378 | 29469990 |
Chronic kidney disease | 19.79 | 10.27 | 64 | 104095 | 36352 | 29434016 |
COVID-19 | 19.77 | 10.27 | 63 | 104096 | 35951 | 29434417 |
Cryptorchism | 19.74 | 10.27 | 29 | 104130 | 1913 | 29468455 |
Mood altered | 19.55 | 10.27 | 68 | 104091 | 8043 | 29462325 |
Cerebral haemorrhage neonatal | 19.54 | 10.27 | 12 | 104147 | 254 | 29470114 |
Tubulointerstitial nephritis | 19.47 | 10.27 | 20 | 104139 | 17623 | 29452745 |
Drug level increased | 19.44 | 10.27 | 123 | 104036 | 18664 | 29451704 |
Periodic limb movement disorder | 19.39 | 10.27 | 9 | 104150 | 105 | 29470263 |
Intentional product misuse | 19.38 | 10.27 | 197 | 103962 | 34464 | 29435904 |
Schizophreniform disorder | 19.35 | 10.27 | 8 | 104151 | 69 | 29470299 |
Blood cholesterol increased | 19.29 | 10.27 | 107 | 104052 | 15488 | 29454880 |
Haemoptysis | 19.29 | 10.27 | 50 | 104109 | 30500 | 29439868 |
Nervousness | 19.29 | 10.27 | 85 | 104074 | 11221 | 29459147 |
Influenza | 19.20 | 10.27 | 79 | 104080 | 41802 | 29428566 |
Sexual activity increased | 19.19 | 10.27 | 6 | 104153 | 20 | 29470348 |
Psychiatric decompensation | 19.09 | 10.27 | 25 | 104134 | 1479 | 29468889 |
Joint swelling | 18.98 | 10.27 | 100 | 104059 | 49530 | 29420838 |
Respiratory failure | 18.91 | 10.27 | 235 | 103924 | 96896 | 29373472 |
Violence-related symptom | 18.71 | 10.27 | 15 | 104144 | 492 | 29469876 |
Crying | 18.62 | 10.27 | 51 | 104108 | 5300 | 29465068 |
Abulia | 18.61 | 10.27 | 15 | 104144 | 496 | 29469872 |
Aspergillus infection | 18.57 | 10.27 | 7 | 104152 | 10574 | 29459794 |
Foetal growth restriction | 18.54 | 10.27 | 41 | 104118 | 3725 | 29466643 |
Hypotension | 18.52 | 10.27 | 532 | 103627 | 193822 | 29276546 |
Dysphemia | 18.25 | 10.27 | 24 | 104135 | 1426 | 29468942 |
Disturbance in sexual arousal | 18.20 | 10.27 | 9 | 104150 | 122 | 29470246 |
Cytopenia | 18.19 | 10.27 | 6 | 104153 | 9853 | 29460515 |
High-pitched crying | 18.15 | 10.27 | 5 | 104154 | 9 | 29470359 |
Blood bilirubin increased | 18.11 | 10.27 | 60 | 104099 | 33833 | 29436535 |
Libido increased | 17.86 | 10.27 | 17 | 104142 | 704 | 29469664 |
Synovitis | 17.82 | 10.27 | 8 | 104151 | 10882 | 29459486 |
Euphoric mood | 17.81 | 10.27 | 47 | 104112 | 4778 | 29465590 |
Lymphomatoid papulosis | 17.81 | 10.27 | 10 | 104149 | 178 | 29470190 |
Gout | 17.74 | 10.27 | 20 | 104139 | 16891 | 29453477 |
Cardiogenic shock | 17.73 | 10.27 | 25 | 104134 | 19165 | 29451203 |
Congenital pulmonary valve atresia | 17.71 | 10.27 | 7 | 104152 | 53 | 29470315 |
Libido disorder | 17.70 | 10.27 | 11 | 104148 | 238 | 29470130 |
Confabulation | 17.69 | 10.27 | 9 | 104150 | 130 | 29470238 |
Apallic syndrome | 17.62 | 10.27 | 11 | 104148 | 240 | 29470128 |
Rash maculo-papular | 17.55 | 10.27 | 37 | 104122 | 24252 | 29446116 |
Loose associations | 17.49 | 10.27 | 7 | 104152 | 55 | 29470313 |
Action tremor | 17.49 | 10.27 | 7 | 104152 | 55 | 29470313 |
Cerebral infarction | 17.48 | 10.27 | 38 | 104121 | 24637 | 29445731 |
Memory impairment | 17.48 | 10.27 | 201 | 103958 | 36269 | 29434099 |
Nephropathy toxic | 17.45 | 10.27 | 8 | 104151 | 10748 | 29459620 |
Pruritus | 17.40 | 10.27 | 298 | 103861 | 116551 | 29353817 |
Arthritis | 17.34 | 10.27 | 39 | 104120 | 24980 | 29445388 |
Gastrointestinal haemorrhage | 17.19 | 10.27 | 188 | 103971 | 79345 | 29391023 |
Therapeutic response unexpected | 17.12 | 10.27 | 68 | 104091 | 8570 | 29461798 |
Ejaculation disorder | 17.05 | 10.27 | 19 | 104140 | 949 | 29469419 |
Blood ethanol increased | 17.01 | 10.27 | 14 | 104145 | 477 | 29469891 |
Grunting | 16.98 | 10.27 | 12 | 104147 | 324 | 29470044 |
Pain in extremity | 16.98 | 10.27 | 280 | 103879 | 110153 | 29360215 |
Hypersomnia | 16.96 | 10.27 | 79 | 104080 | 10675 | 29459693 |
Dysarthria | 16.95 | 10.27 | 175 | 103984 | 30736 | 29439632 |
Physical assault | 16.94 | 10.27 | 20 | 104139 | 1064 | 29469304 |
Granulocytopenia | 16.90 | 10.27 | 53 | 104106 | 5941 | 29464427 |
Coloboma | 16.88 | 10.27 | 9 | 104150 | 144 | 29470224 |
Polyneuropathy | 16.86 | 10.27 | 11 | 104148 | 12141 | 29458227 |
Acute myeloid leukaemia | 16.82 | 10.27 | 20 | 104139 | 16493 | 29453875 |
Alcohol poisoning | 16.78 | 10.27 | 35 | 104124 | 3054 | 29467314 |
Obesity | 16.71 | 10.27 | 74 | 104085 | 9789 | 29460579 |
Alveolar bone resorption | 16.64 | 10.27 | 5 | 104154 | 14 | 29470354 |
Thrombotic microangiopathy | 16.52 | 10.27 | 5 | 104154 | 8676 | 29461692 |
Blood triglycerides increased | 16.51 | 10.27 | 89 | 104070 | 12745 | 29457623 |
Hypoglycaemia neonatal | 16.45 | 10.27 | 25 | 104134 | 1699 | 29468669 |
Septum pellucidum agenesis | 16.39 | 10.27 | 7 | 104152 | 66 | 29470302 |
Neonatal disorder | 16.32 | 10.27 | 17 | 104142 | 786 | 29469582 |
Acute myocardial infarction | 16.16 | 10.27 | 102 | 104057 | 48336 | 29422032 |
Duplicate therapy error | 16.14 | 10.27 | 8 | 104151 | 109 | 29470259 |
Tongue spasm | 16.09 | 10.27 | 6 | 104153 | 38 | 29470330 |
Cellulitis | 16.09 | 10.27 | 95 | 104064 | 45745 | 29424623 |
Metabolic acidosis | 16.06 | 10.27 | 73 | 104086 | 37589 | 29432779 |
Impaired work ability | 16.03 | 10.27 | 50 | 104109 | 5590 | 29464778 |
Urinary incontinence | 15.89 | 10.27 | 106 | 104053 | 16375 | 29453993 |
Respiratory dyskinesia | 15.70 | 10.27 | 5 | 104154 | 18 | 29470350 |
Ejaculation delayed | 15.67 | 10.27 | 10 | 104149 | 227 | 29470141 |
Compulsive sexual behaviour | 15.63 | 10.27 | 10 | 104149 | 228 | 29470140 |
Transient tachypnoea of the newborn | 15.61 | 10.27 | 9 | 104150 | 169 | 29470199 |
Posture abnormal | 15.51 | 10.27 | 26 | 104133 | 1921 | 29468447 |
Intentional product use issue | 15.49 | 10.27 | 87 | 104072 | 42411 | 29427957 |
Weight increased | 15.38 | 10.27 | 366 | 103793 | 76301 | 29394067 |
Hepatic failure | 15.36 | 10.27 | 58 | 104101 | 31454 | 29438914 |
Kidney transplant rejection | 15.35 | 10.27 | 3 | 104156 | 7002 | 29463366 |
Psychomotor retardation | 15.33 | 10.27 | 33 | 104126 | 2943 | 29467425 |
Paraneoplastic rash | 15.21 | 10.27 | 7 | 104152 | 80 | 29470288 |
Intraventricular haemorrhage neonatal | 15.18 | 10.27 | 10 | 104149 | 240 | 29470128 |
Malpositioned teeth | 15.09 | 10.27 | 5 | 104154 | 21 | 29470347 |
Pneumonia bacterial | 15.07 | 10.27 | 7 | 104152 | 9336 | 29461032 |
Hyperuricaemia | 14.99 | 10.27 | 3 | 104156 | 6886 | 29463482 |
Obsessive rumination | 14.97 | 10.27 | 4 | 104155 | 6 | 29470362 |
Drug screen false positive | 14.92 | 10.27 | 15 | 104144 | 665 | 29469703 |
Palmar-plantar erythrodysaesthesia syndrome | 14.90 | 10.27 | 18 | 104141 | 14741 | 29455627 |
Hypersexuality | 14.88 | 10.27 | 21 | 104138 | 1335 | 29469033 |
Temperature regulation disorder | 14.87 | 10.27 | 14 | 104145 | 572 | 29469796 |
Gastrooesophageal reflux disease | 14.83 | 10.27 | 173 | 103986 | 31323 | 29439045 |
Dissociative identity disorder | 14.73 | 10.27 | 5 | 104154 | 23 | 29470345 |
Cardiac failure acute | 14.66 | 10.27 | 7 | 104152 | 9185 | 29461183 |
Red blood cell elliptocytes present | 14.62 | 10.27 | 7 | 104152 | 88 | 29470280 |
Gangrene neonatal | 14.59 | 10.27 | 9 | 104150 | 192 | 29470176 |
Feelings of worthlessness | 14.58 | 10.27 | 10 | 104149 | 257 | 29470111 |
Drug intolerance | 14.58 | 10.27 | 105 | 104054 | 48274 | 29422094 |
Obsessive-compulsive symptom | 14.55 | 10.27 | 7 | 104152 | 89 | 29470279 |
Illusion | 14.52 | 10.27 | 15 | 104144 | 687 | 29469681 |
Hypocalcaemia | 14.49 | 10.27 | 32 | 104127 | 20633 | 29449735 |
Activation syndrome | 14.35 | 10.27 | 7 | 104152 | 92 | 29470276 |
Emotional disorder | 14.27 | 10.27 | 44 | 104115 | 4887 | 29465481 |
Pulmonary microemboli | 14.24 | 10.27 | 4 | 104155 | 8 | 29470360 |
Substance use disorder | 14.22 | 10.27 | 10 | 104149 | 268 | 29470100 |
Congenital hearing disorder | 14.15 | 10.27 | 7 | 104152 | 95 | 29470273 |
Hippocampal sclerosis | 14.15 | 10.27 | 7 | 104152 | 95 | 29470273 |
Anuria | 14.12 | 10.27 | 8 | 104151 | 9533 | 29460835 |
Strabismus congenital | 14.08 | 10.27 | 5 | 104154 | 27 | 29470341 |
Peritonitis | 14.01 | 10.27 | 19 | 104140 | 14805 | 29455563 |
Bladder dilatation | 13.97 | 10.27 | 20 | 104139 | 1288 | 29469080 |
Constricted affect | 13.96 | 10.27 | 3 | 104156 | 0 | 29470368 |
Enteric neuropathy | 13.96 | 10.27 | 3 | 104156 | 0 | 29470368 |
Arterial ligation | 13.96 | 10.27 | 3 | 104156 | 0 | 29470368 |
Foetal damage | 13.96 | 10.27 | 3 | 104156 | 0 | 29470368 |
Nasal cavity packing | 13.96 | 10.27 | 3 | 104156 | 0 | 29470368 |
Eczema | 13.81 | 10.27 | 17 | 104142 | 13809 | 29456559 |
Painful erection | 13.81 | 10.27 | 9 | 104150 | 212 | 29470156 |
Rebound psychosis | 13.79 | 10.27 | 8 | 104151 | 152 | 29470216 |
Poor feeding infant | 13.79 | 10.27 | 12 | 104147 | 442 | 29469926 |
Maculopathy | 13.77 | 10.27 | 16 | 104143 | 837 | 29469531 |
Wrong patient received product | 13.76 | 10.27 | 27 | 104132 | 2255 | 29468113 |
Hallucinations, mixed | 13.73 | 10.27 | 28 | 104131 | 2405 | 29467963 |
Muscle contractions involuntary | 13.68 | 10.27 | 23 | 104136 | 1704 | 29468664 |
Colitis | 13.67 | 10.27 | 60 | 104099 | 31188 | 29439180 |
Abdominal distension | 13.66 | 10.27 | 100 | 104059 | 45811 | 29424557 |
Transposition of the great vessels | 13.65 | 10.27 | 12 | 104147 | 448 | 29469920 |
Genital anaesthesia | 13.63 | 10.27 | 4 | 104155 | 10 | 29470358 |
Self-medication | 13.61 | 10.27 | 26 | 104133 | 2128 | 29468240 |
Liver disorder | 13.57 | 10.27 | 51 | 104108 | 27698 | 29442670 |
Drug hypersensitivity | 13.55 | 10.27 | 326 | 103833 | 68080 | 29402288 |
Fungal infection | 13.49 | 10.27 | 17 | 104142 | 13668 | 29456700 |
Emotional poverty | 13.45 | 10.27 | 12 | 104147 | 457 | 29469911 |
Hypoalbuminaemia | 13.41 | 10.27 | 10 | 104149 | 10295 | 29460073 |
Cataract congenital | 13.40 | 10.27 | 6 | 104153 | 64 | 29470304 |
Drug eruption | 13.40 | 10.27 | 24 | 104135 | 16717 | 29453651 |
Post-traumatic stress disorder | 13.38 | 10.27 | 22 | 104137 | 1600 | 29468768 |
Dysgraphia | 13.38 | 10.27 | 25 | 104134 | 2013 | 29468355 |
Sneezing | 13.35 | 10.27 | 40 | 104119 | 4374 | 29465994 |
Illness anxiety disorder | 13.30 | 10.27 | 8 | 104151 | 163 | 29470205 |
Somnambulism | 13.26 | 10.27 | 30 | 104129 | 2768 | 29467600 |
Cytomegalovirus viraemia | 13.25 | 10.27 | 3 | 104156 | 6317 | 29464051 |
Hepatocellular injury | 13.24 | 10.27 | 35 | 104124 | 21208 | 29449160 |
Pathogen resistance | 13.22 | 10.27 | 6 | 104153 | 8110 | 29462258 |
Onychomycosis | 13.17 | 10.27 | 25 | 104134 | 2037 | 29468331 |
Neutrophil count increased | 13.14 | 10.27 | 93 | 104066 | 14649 | 29455719 |
Optic ischaemic neuropathy | 13.11 | 10.27 | 24 | 104135 | 1902 | 29468466 |
Poverty of thought content | 13.11 | 10.27 | 5 | 104154 | 34 | 29470334 |
Skin indentation | 13.11 | 10.27 | 4 | 104155 | 12 | 29470356 |
Contraindicated product administered | 13.05 | 10.27 | 28 | 104131 | 18238 | 29452130 |
Delirium | 13.02 | 10.27 | 203 | 103956 | 39194 | 29431174 |
Vascular dementia | 12.98 | 10.27 | 12 | 104147 | 479 | 29469889 |
Feeling drunk | 12.96 | 10.27 | 22 | 104137 | 1642 | 29468726 |
Hyperprolactinaemia | 12.96 | 10.27 | 19 | 104140 | 1251 | 29469117 |
Selective mutism | 12.93 | 10.27 | 6 | 104153 | 70 | 29470298 |
Blood urea increased | 12.90 | 10.27 | 53 | 104106 | 28059 | 29442309 |
Transaminases increased | 12.89 | 10.27 | 39 | 104120 | 22623 | 29447745 |
Device related infection | 12.89 | 10.27 | 22 | 104137 | 15614 | 29454754 |
Salivary hypersecretion | 12.86 | 10.27 | 56 | 104103 | 7353 | 29463015 |
Cardiac failure congestive | 12.83 | 10.27 | 191 | 103968 | 76390 | 29393978 |
Psychotic symptom | 12.79 | 10.27 | 20 | 104139 | 1394 | 29468974 |
Pulmonary embolism | 12.78 | 10.27 | 191 | 103968 | 76343 | 29394025 |
Brugada syndrome | 12.76 | 10.27 | 14 | 104145 | 687 | 29469681 |
Self-injurious ideation | 12.74 | 10.27 | 21 | 104138 | 1530 | 29468838 |
Stoma site infection | 12.73 | 10.27 | 14 | 104145 | 689 | 29469679 |
Suspected suicide | 12.70 | 10.27 | 37 | 104122 | 3983 | 29466385 |
COVID-19 pneumonia | 12.70 | 10.27 | 9 | 104150 | 9513 | 29460855 |
Sinusitis | 12.69 | 10.27 | 70 | 104089 | 34280 | 29436088 |
Deep vein thrombosis | 12.67 | 10.27 | 135 | 104024 | 57264 | 29413104 |
Diffuse vasculitis | 12.63 | 10.27 | 6 | 104153 | 74 | 29470294 |
Gaze palsy | 12.63 | 10.27 | 19 | 104140 | 1280 | 29469088 |
Abnormal dreams | 12.55 | 10.27 | 53 | 104106 | 6867 | 29463501 |
Decreased interest | 12.53 | 10.27 | 25 | 104134 | 2113 | 29468255 |
Skin turgor decreased | 12.53 | 10.27 | 11 | 104148 | 410 | 29469958 |
Second primary malignancy | 12.51 | 10.27 | 4 | 104155 | 6701 | 29463667 |
Fallot's tetralogy | 12.48 | 10.27 | 8 | 104151 | 183 | 29470185 |
Depression suicidal | 12.45 | 10.27 | 19 | 104140 | 1296 | 29469072 |
Pregnancy | 12.45 | 10.27 | 9 | 104150 | 252 | 29470116 |
Body mass index increased | 12.43 | 10.27 | 15 | 104144 | 817 | 29469551 |
Enterocolitis | 12.40 | 10.27 | 4 | 104155 | 6662 | 29463706 |
Urinary retention | 12.37 | 10.27 | 169 | 103990 | 31729 | 29438639 |
Drug dose titration not performed | 12.36 | 10.27 | 9 | 104150 | 255 | 29470113 |
Immune reconstitution inflammatory syndrome | 12.35 | 10.27 | 6 | 104153 | 7796 | 29462572 |
Proteinuria | 12.34 | 10.27 | 23 | 104136 | 15781 | 29454587 |
Umbilical cord abnormality | 12.31 | 10.27 | 5 | 104154 | 41 | 29470327 |
Sleep inertia | 12.23 | 10.27 | 4 | 104155 | 16 | 29470352 |
Blood pressure fluctuation | 12.23 | 10.27 | 33 | 104126 | 19861 | 29450507 |
Alanine aminotransferase increased | 12.21 | 10.27 | 176 | 103983 | 70768 | 29399600 |
Respiratory arrest | 12.21 | 10.27 | 142 | 104017 | 25691 | 29444677 |
Gun shot wound | 12.20 | 10.27 | 17 | 104142 | 1068 | 29469300 |
Hepatorenal failure | 12.18 | 10.27 | 12 | 104147 | 519 | 29469849 |
Schizoaffective disorder | 12.11 | 10.27 | 17 | 104142 | 1075 | 29469293 |
Labelled drug-drug interaction medication error | 12.09 | 10.27 | 15 | 104144 | 12144 | 29458224 |
Premature baby | 12.06 | 10.27 | 103 | 104056 | 17177 | 29453191 |
Osteonecrosis of jaw | 12.05 | 10.27 | 25 | 104134 | 16485 | 29453883 |
Squamous cell carcinoma | 12.03 | 10.27 | 11 | 104148 | 10240 | 29460128 |
Electrocardiogram QT interval abnormal | 12.03 | 10.27 | 6 | 104153 | 83 | 29470285 |
Anaphylactic reaction | 12.03 | 10.27 | 53 | 104106 | 27520 | 29442848 |
Cough | 12.02 | 10.27 | 347 | 103812 | 126380 | 29343988 |
Skin infection | 12.00 | 10.27 | 4 | 104155 | 6523 | 29463845 |
Tension | 11.98 | 10.27 | 23 | 104136 | 1890 | 29468478 |
Moaning | 11.98 | 10.27 | 14 | 104145 | 737 | 29469631 |
Mixed dementia | 11.97 | 10.27 | 9 | 104150 | 268 | 29470100 |
Dehydration | 11.97 | 10.27 | 310 | 103849 | 114438 | 29355930 |
End stage renal disease | 11.97 | 10.27 | 6 | 104153 | 7658 | 29462710 |
Renal injury | 11.91 | 10.27 | 11 | 104148 | 10191 | 29460177 |
Abdominoplasty | 11.89 | 10.27 | 3 | 104156 | 3 | 29470365 |
Congenital gastric anomaly | 11.89 | 10.27 | 3 | 104156 | 3 | 29470365 |
Colostomy infection | 11.89 | 10.27 | 3 | 104156 | 3 | 29470365 |
Foetal death | 11.86 | 10.27 | 8 | 104151 | 200 | 29470168 |
Bankruptcy | 11.85 | 10.27 | 4 | 104155 | 18 | 29470350 |
Psoriatic arthropathy | 11.81 | 10.27 | 21 | 104138 | 14670 | 29455698 |
Herpes zoster | 11.80 | 10.27 | 60 | 104099 | 29992 | 29440376 |
Enuresis | 11.78 | 10.27 | 24 | 104135 | 2060 | 29468308 |
Type 2 diabetes mellitus | 11.71 | 10.27 | 85 | 104074 | 13496 | 29456872 |
Discouragement | 11.70 | 10.27 | 7 | 104152 | 141 | 29470227 |
Velopharyngeal incompetence | 11.68 | 10.27 | 4 | 104155 | 19 | 29470349 |
Platelet aggregation decreased | 11.68 | 10.27 | 4 | 104155 | 19 | 29470349 |
Hepatitis | 11.66 | 10.27 | 36 | 104123 | 20747 | 29449621 |
Disseminated intravascular coagulation | 11.64 | 10.27 | 34 | 104125 | 19946 | 29450422 |
Drug tolerance increased | 11.63 | 10.27 | 11 | 104148 | 452 | 29469916 |
Cholangitis | 11.62 | 10.27 | 6 | 104153 | 7531 | 29462837 |
Flashback | 11.53 | 10.27 | 7 | 104152 | 145 | 29470223 |
Facial discomfort | 11.51 | 10.27 | 4 | 104155 | 20 | 29470348 |
Shock haemorrhagic | 11.51 | 10.27 | 10 | 104149 | 9541 | 29460827 |
Food interaction | 11.49 | 10.27 | 15 | 104144 | 885 | 29469483 |
Hypomagnesaemia | 11.49 | 10.27 | 28 | 104131 | 17440 | 29452928 |
Oxygen saturation decreased | 11.47 | 10.27 | 102 | 104057 | 44835 | 29425533 |
Stress | 11.47 | 10.27 | 121 | 104038 | 21369 | 29448999 |
Mallory-Weiss syndrome | 11.46 | 10.27 | 18 | 104141 | 1259 | 29469109 |
Delusional disorder, unspecified type | 11.43 | 10.27 | 13 | 104146 | 664 | 29469704 |
Dyskinesia neonatal | 11.43 | 10.27 | 3 | 104156 | 4 | 29470364 |
Butterfly rash | 11.42 | 10.27 | 6 | 104153 | 93 | 29470275 |
Product use issue | 11.35 | 10.27 | 121 | 104038 | 51323 | 29419045 |
Vesicoureteric reflux | 11.32 | 10.27 | 7 | 104152 | 150 | 29470218 |
Pyromania | 11.28 | 10.27 | 5 | 104154 | 52 | 29470316 |
Daydreaming | 11.25 | 10.27 | 11 | 104148 | 471 | 29469897 |
Cleft palate | 11.22 | 10.27 | 12 | 104147 | 572 | 29469796 |
Neonatal seizure | 11.22 | 10.27 | 11 | 104148 | 473 | 29469895 |
Haemolytic anaemia | 11.18 | 10.27 | 10 | 104149 | 9409 | 29460959 |
Loss of employment | 11.16 | 10.27 | 11 | 104148 | 476 | 29469892 |
Morbid thoughts | 11.13 | 10.27 | 8 | 104151 | 222 | 29470146 |
Yawning | 11.10 | 10.27 | 11 | 104148 | 479 | 29469889 |
Dyspnoea exertional | 11.09 | 10.27 | 79 | 104080 | 36411 | 29433957 |
Poverty of speech | 11.07 | 10.27 | 8 | 104151 | 224 | 29470144 |
Panic reaction | 11.07 | 10.27 | 18 | 104141 | 1297 | 29469071 |
Pseudocholinesterase deficiency | 11.05 | 10.27 | 4 | 104155 | 23 | 29470345 |
Hypersensitivity | 11.05 | 10.27 | 126 | 104033 | 52777 | 29417591 |
Serum ferritin increased | 11.04 | 10.27 | 3 | 104156 | 5585 | 29464783 |
Pericardial effusion | 11.02 | 10.27 | 38 | 104121 | 21170 | 29449198 |
Craniosynostosis | 11.00 | 10.27 | 9 | 104150 | 304 | 29470064 |
Panic disorder | 11.00 | 10.27 | 17 | 104142 | 1173 | 29469195 |
Localised infection | 10.88 | 10.27 | 20 | 104139 | 13796 | 29456572 |
General symptom | 10.88 | 10.27 | 14 | 104145 | 814 | 29469554 |
Dysaesthesia | 10.87 | 10.27 | 23 | 104136 | 2027 | 29468341 |
Haematochezia | 10.79 | 10.27 | 81 | 104078 | 36902 | 29433466 |
Neurotoxicity | 10.77 | 10.27 | 22 | 104137 | 14591 | 29455777 |
Congenital skin dimples | 10.70 | 10.27 | 7 | 104152 | 166 | 29470202 |
PCO2 abnormal | 10.68 | 10.27 | 3 | 104156 | 6 | 29470362 |
Platelet disorder | 10.67 | 10.27 | 18 | 104141 | 1337 | 29469031 |
Progressive multifocal leukoencephalopathy | 10.66 | 10.27 | 9 | 104150 | 8710 | 29461658 |
Dementia | 10.66 | 10.27 | 74 | 104085 | 11584 | 29458784 |
Epstein-Barr virus infection | 10.64 | 10.27 | 5 | 104154 | 6624 | 29463744 |
Movement disorder | 10.58 | 10.27 | 67 | 104092 | 10170 | 29460198 |
Hyperbilirubinaemia | 10.58 | 10.27 | 23 | 104136 | 14911 | 29455457 |
Bronchospasm | 10.48 | 10.27 | 11 | 104148 | 9598 | 29460770 |
Chorea | 10.48 | 10.27 | 15 | 104144 | 966 | 29469402 |
Affect lability | 10.45 | 10.27 | 31 | 104128 | 3371 | 29466997 |
Lactic acidosis | 10.45 | 10.27 | 63 | 104096 | 30184 | 29440184 |
Diverticulitis | 10.41 | 10.27 | 30 | 104129 | 17674 | 29452694 |
Partial seizures with secondary generalisation | 10.39 | 10.27 | 8 | 104151 | 247 | 29470121 |
Orthostatic tremor | 10.37 | 10.27 | 3 | 104156 | 7 | 29470361 |
Rash pruritic | 10.36 | 10.27 | 42 | 104117 | 22321 | 29448047 |
Lethargy | 10.35 | 10.27 | 188 | 103971 | 37392 | 29432976 |
Peripheral artery thrombosis | 10.33 | 10.27 | 23 | 104136 | 2099 | 29468269 |
Pharyngeal swelling | 10.32 | 10.27 | 19 | 104140 | 1512 | 29468856 |
Accidental overdose | 10.32 | 10.27 | 101 | 104058 | 17492 | 29452876 |
Personality disorder | 10.32 | 10.27 | 16 | 104143 | 1107 | 29469261 |
Arthropathy | 10.29 | 10.27 | 40 | 104119 | 21514 | 29448854 |
Hepatocellular carcinoma | 10.28 | 10.27 | 6 | 104153 | 7032 | 29463336 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Serotonin syndrome | 1332.99 | 9.70 | 1161 | 253543 | 38121 | 64205907 |
Intentional self-injury | 1236.40 | 9.70 | 979 | 253725 | 28065 | 64215963 |
Suicidal ideation | 1113.00 | 9.70 | 1343 | 253361 | 65199 | 64178829 |
Intentional overdose | 916.35 | 9.70 | 1428 | 253276 | 88516 | 64155512 |
Suicide attempt | 903.58 | 9.70 | 1252 | 253452 | 69755 | 64174273 |
Drug abuse | 759.17 | 9.70 | 1639 | 253065 | 130735 | 64113293 |
Drug interaction | 675.12 | 9.70 | 3023 | 251681 | 359060 | 63884968 |
Depression | 650.52 | 9.70 | 1890 | 252814 | 181401 | 64062627 |
Anxiety | 619.46 | 9.70 | 1983 | 252721 | 200666 | 64043362 |
Completed suicide | 559.79 | 9.70 | 2052 | 252652 | 222362 | 64021666 |
Agitation | 476.63 | 9.70 | 1068 | 253636 | 87299 | 64156729 |
Tremor | 401.36 | 9.70 | 1393 | 253311 | 146837 | 64097191 |
Toxicity to various agents | 330.85 | 9.70 | 2511 | 252193 | 361002 | 63883026 |
Akathisia | 328.84 | 9.70 | 309 | 254395 | 11201 | 64232827 |
Sopor | 325.79 | 9.70 | 488 | 254216 | 29173 | 64214855 |
Synovitis | 303.39 | 9.70 | 23 | 254681 | 99067 | 64144961 |
Aggression | 292.04 | 9.70 | 596 | 254108 | 45636 | 64198392 |
Withdrawal syndrome | 276.03 | 9.70 | 399 | 254305 | 23093 | 64220935 |
Overdose | 260.94 | 9.70 | 1284 | 253420 | 158282 | 64085746 |
Somnolence | 254.16 | 9.70 | 1522 | 253182 | 202123 | 64041905 |
Pyrexia | 238.75 | 9.70 | 1266 | 253438 | 557378 | 63686650 |
Confusional state | 236.72 | 9.70 | 1803 | 252901 | 259341 | 63984687 |
Mania | 226.43 | 9.70 | 300 | 254404 | 15986 | 64228042 |
Paranoia | 220.88 | 9.70 | 297 | 254407 | 16055 | 64227973 |
Bruxism | 219.14 | 9.70 | 151 | 254553 | 3473 | 64240555 |
Drug intolerance | 217.50 | 9.70 | 253 | 254451 | 187739 | 64056289 |
Restlessness | 212.28 | 9.70 | 479 | 254225 | 39306 | 64204722 |
Abnormal behaviour | 211.80 | 9.70 | 433 | 254271 | 33189 | 64210839 |
Hyponatraemia | 210.81 | 9.70 | 1148 | 253556 | 147191 | 64096837 |
Hand deformity | 209.15 | 9.70 | 9 | 254695 | 62762 | 64181266 |
Hallucination, auditory | 208.26 | 9.70 | 294 | 254410 | 16645 | 64227383 |
Dyskinesia | 204.36 | 9.70 | 469 | 254235 | 38919 | 64205109 |
Infusion related reaction | 203.89 | 9.70 | 209 | 254495 | 164258 | 64079770 |
Irritability | 201.20 | 9.70 | 447 | 254257 | 36299 | 64207729 |
Rheumatoid arthritis | 201.16 | 9.70 | 211 | 254493 | 164083 | 64079945 |
Joint swelling | 200.22 | 9.70 | 339 | 254365 | 215043 | 64028985 |
Febrile neutropenia | 197.87 | 9.70 | 271 | 254433 | 187386 | 64056642 |
Panic attack | 191.63 | 9.70 | 317 | 254387 | 20636 | 64223392 |
Extrapyramidal disorder | 191.32 | 9.70 | 305 | 254399 | 19247 | 64224781 |
Psychotic disorder | 189.74 | 9.70 | 421 | 254283 | 34157 | 64209871 |
Hallucination | 188.13 | 9.70 | 674 | 254030 | 72114 | 64171914 |
Contraindicated product administered | 184.06 | 9.70 | 98 | 254606 | 107731 | 64136297 |
Drug withdrawal syndrome | 180.81 | 9.70 | 389 | 254315 | 30902 | 64213126 |
Treatment failure | 177.27 | 9.70 | 122 | 254582 | 116694 | 64127334 |
Off label use | 175.69 | 9.70 | 1626 | 253078 | 631180 | 63612848 |
Insomnia | 164.29 | 9.70 | 1339 | 253365 | 196497 | 64047531 |
Acute kidney injury | 158.99 | 9.70 | 1080 | 253624 | 448160 | 63795868 |
Anger | 157.39 | 9.70 | 248 | 254456 | 15493 | 64228535 |
Mydriasis | 154.15 | 9.70 | 242 | 254462 | 15070 | 64228958 |
Renal impairment | 152.60 | 9.70 | 185 | 254519 | 134832 | 64109196 |
Dystonia | 152.24 | 9.70 | 270 | 254434 | 18595 | 64225433 |
Malignant neoplasm progression | 148.48 | 9.70 | 136 | 254568 | 112735 | 64131293 |
Arthropathy | 148.44 | 9.70 | 155 | 254549 | 120812 | 64123216 |
Arthralgia | 147.30 | 9.70 | 1082 | 253622 | 441178 | 63802850 |
Parkinsonism | 147.25 | 9.70 | 229 | 254475 | 14144 | 64229884 |
Systemic lupus erythematosus | 145.53 | 9.70 | 62 | 254642 | 77550 | 64166478 |
Obsessive-compulsive disorder | 144.68 | 9.70 | 133 | 254571 | 4685 | 64239343 |
Homicidal ideation | 143.28 | 9.70 | 112 | 254592 | 3145 | 64240883 |
Disturbance in attention | 140.98 | 9.70 | 419 | 254285 | 40655 | 64203373 |
Delusion | 140.48 | 9.70 | 254 | 254450 | 17760 | 64226268 |
Nasopharyngitis | 135.88 | 9.70 | 364 | 254340 | 195709 | 64048319 |
Tic | 134.99 | 9.70 | 99 | 254605 | 2520 | 64241508 |
Stomatitis | 134.98 | 9.70 | 140 | 254564 | 109465 | 64134563 |
Rash | 134.58 | 9.70 | 1161 | 253543 | 457388 | 63786640 |
Pericarditis | 134.16 | 9.70 | 40 | 254664 | 62476 | 64181552 |
Thrombocytopenia | 133.83 | 9.70 | 445 | 254259 | 223356 | 64020672 |
Depressed mood | 133.83 | 9.70 | 411 | 254293 | 40601 | 64203427 |
Mood swings | 133.30 | 9.70 | 244 | 254460 | 17224 | 64226804 |
Nightmare | 125.92 | 9.70 | 265 | 254439 | 20728 | 64223300 |
Neutropenia | 123.90 | 9.70 | 506 | 254198 | 239118 | 64004910 |
Electrocardiogram QT prolonged | 123.85 | 9.70 | 631 | 254073 | 78817 | 64165211 |
Pancytopenia | 123.73 | 9.70 | 236 | 254468 | 143073 | 64100955 |
Drug ineffective | 123.46 | 9.70 | 2460 | 252244 | 837787 | 63406241 |
Bradykinesia | 122.14 | 9.70 | 140 | 254564 | 6420 | 64237608 |
Hyperhidrosis | 120.05 | 9.70 | 875 | 253829 | 124045 | 64119983 |
Self-injurious ideation | 119.59 | 9.70 | 100 | 254604 | 3097 | 64240931 |
Muscle rigidity | 118.38 | 9.70 | 232 | 254472 | 17241 | 64226787 |
Feeling abnormal | 118.35 | 9.70 | 918 | 253786 | 132684 | 64111344 |
Psychomotor hyperactivity | 118.12 | 9.70 | 208 | 254496 | 14243 | 64229785 |
Glossodynia | 117.64 | 9.70 | 54 | 254650 | 64642 | 64179386 |
Hepatic enzyme increased | 117.50 | 9.70 | 208 | 254496 | 129735 | 64114293 |
Apathy | 116.52 | 9.70 | 180 | 254524 | 11052 | 64232976 |
Hypomania | 116.12 | 9.70 | 127 | 254577 | 5527 | 64238501 |
Thinking abnormal | 114.06 | 9.70 | 181 | 254523 | 11375 | 64232653 |
Seizure | 113.82 | 9.70 | 1082 | 253622 | 165810 | 64078218 |
Anaemia | 111.37 | 9.70 | 958 | 253746 | 377722 | 63866306 |
Loss of libido | 110.83 | 9.70 | 85 | 254619 | 2319 | 64241709 |
Neuroleptic malignant syndrome | 110.71 | 9.70 | 280 | 254424 | 24716 | 64219312 |
Hallucination, visual | 110.20 | 9.70 | 299 | 254405 | 27535 | 64216493 |
Homicide | 109.82 | 9.70 | 64 | 254640 | 1087 | 64242941 |
Disorientation | 108.66 | 9.70 | 473 | 254231 | 55355 | 64188673 |
Social avoidant behaviour | 107.15 | 9.70 | 110 | 254594 | 4447 | 64239581 |
Priapism | 106.59 | 9.70 | 103 | 254601 | 3867 | 64240161 |
Colitis microscopic | 106.55 | 9.70 | 139 | 254565 | 7293 | 64236735 |
Pneumonia | 106.36 | 9.70 | 1563 | 253141 | 558013 | 63686015 |
Peripheral swelling | 104.17 | 9.70 | 448 | 254256 | 208705 | 64035323 |
Treatment noncompliance | 103.38 | 9.70 | 392 | 254312 | 43090 | 64200938 |
Loss of consciousness | 102.20 | 9.70 | 964 | 253740 | 147401 | 64096627 |
Bradyphrenia | 102.18 | 9.70 | 154 | 254550 | 9252 | 64234776 |
Intrusive thoughts | 100.85 | 9.70 | 42 | 254662 | 325 | 64243703 |
Wound | 100.74 | 9.70 | 92 | 254612 | 76385 | 64167643 |
Alopecia | 98.63 | 9.70 | 330 | 254374 | 165360 | 64078668 |
Oromandibular dystonia | 98.48 | 9.70 | 55 | 254649 | 858 | 64243170 |
Dizziness | 98.26 | 9.70 | 2306 | 252398 | 427857 | 63816171 |
C-reactive protein increased | 98.03 | 9.70 | 139 | 254565 | 94770 | 64149258 |
Cytomegalovirus infection | 97.71 | 9.70 | 15 | 254689 | 37184 | 64206844 |
Cardiac failure | 97.64 | 9.70 | 238 | 254466 | 132135 | 64111893 |
Blood prolactin increased | 97.50 | 9.70 | 93 | 254611 | 3435 | 64240593 |
Therapeutic product effect decreased | 96.92 | 9.70 | 193 | 254511 | 115158 | 64128870 |
General physical health deterioration | 96.90 | 9.70 | 446 | 254258 | 203979 | 64040049 |
Catatonia | 96.26 | 9.70 | 134 | 254570 | 7486 | 64236542 |
Inappropriate antidiuretic hormone secretion | 95.93 | 9.70 | 247 | 254457 | 22042 | 64221986 |
Crying | 95.26 | 9.70 | 231 | 254473 | 19859 | 64224169 |
Major depression | 95.10 | 9.70 | 135 | 254569 | 7681 | 64236347 |
Sexual dysfunction | 94.29 | 9.70 | 122 | 254582 | 6349 | 64237679 |
Myoclonus | 91.72 | 9.70 | 262 | 254442 | 24856 | 64219172 |
Suicidal behaviour | 89.23 | 9.70 | 81 | 254623 | 2806 | 64241222 |
Amnesia | 88.68 | 9.70 | 402 | 254302 | 47867 | 64196161 |
Muscle twitching | 88.54 | 9.70 | 217 | 254487 | 18781 | 64225247 |
Anorgasmia | 88.52 | 9.70 | 52 | 254652 | 897 | 64243131 |
Tachyphrenia | 87.96 | 9.70 | 67 | 254637 | 1809 | 64242219 |
Sepsis | 87.78 | 9.70 | 541 | 254163 | 229800 | 64014228 |
Septic shock | 87.22 | 9.70 | 178 | 254526 | 105259 | 64138769 |
Sleep disorder due to general medical condition, insomnia type | 86.74 | 9.70 | 4 | 254700 | 26266 | 64217762 |
Delirium | 86.68 | 9.70 | 518 | 254186 | 68676 | 64175352 |
Emotional distress | 86.59 | 9.70 | 326 | 254378 | 35712 | 64208316 |
Neuropathy peripheral | 85.34 | 9.70 | 213 | 254491 | 117312 | 64126716 |
Sinusitis | 83.89 | 9.70 | 295 | 254409 | 145633 | 64098395 |
Libido decreased | 83.89 | 9.70 | 99 | 254605 | 4685 | 64239343 |
Galactorrhoea | 83.59 | 9.70 | 82 | 254622 | 3137 | 64240891 |
Rheumatoid factor positive | 83.34 | 9.70 | 18 | 254686 | 34920 | 64209108 |
Infection | 80.86 | 9.70 | 415 | 254289 | 184465 | 64059563 |
Poisoning deliberate | 80.84 | 9.70 | 170 | 254534 | 13288 | 64230740 |
Hyperprolactinaemia | 79.50 | 9.70 | 89 | 254615 | 3976 | 64240052 |
Mucosal inflammation | 79.25 | 9.70 | 78 | 254626 | 62506 | 64181522 |
Maculopathy | 79.06 | 9.70 | 71 | 254633 | 2425 | 64241603 |
Sedation | 78.94 | 9.70 | 349 | 254355 | 41113 | 64202915 |
Psychomotor retardation | 78.14 | 9.70 | 99 | 254605 | 5044 | 64238984 |
Mental disorder | 78.02 | 9.70 | 256 | 254448 | 26189 | 64217839 |
Folliculitis | 77.04 | 9.70 | 13 | 254691 | 30064 | 64213964 |
Helicobacter infection | 76.25 | 9.70 | 28 | 254676 | 38334 | 64205694 |
Hyperreflexia | 76.19 | 9.70 | 116 | 254588 | 7032 | 64236996 |
Fall | 76.00 | 9.70 | 2169 | 252535 | 414657 | 63829371 |
Product substitution issue | 75.91 | 9.70 | 197 | 254507 | 17664 | 64226364 |
C-reactive protein abnormal | 75.64 | 9.70 | 12 | 254692 | 29035 | 64214993 |
Restless legs syndrome | 75.03 | 9.70 | 191 | 254513 | 16925 | 64227103 |
Hypersensitivity | 74.52 | 9.70 | 462 | 254242 | 195990 | 64048038 |
Pleural effusion | 73.98 | 9.70 | 254 | 254450 | 126305 | 64117723 |
Disease progression | 73.91 | 9.70 | 298 | 254406 | 141382 | 64102646 |
Drug hypersensitivity | 72.95 | 9.70 | 1332 | 253372 | 236483 | 64007545 |
Trismus | 72.35 | 9.70 | 93 | 254611 | 4808 | 64239220 |
Swelling | 72.13 | 9.70 | 356 | 254348 | 159862 | 64084166 |
Duodenal ulcer perforation | 71.00 | 9.70 | 24 | 254680 | 34601 | 64209427 |
Emotional disorder | 69.71 | 9.70 | 154 | 254550 | 12453 | 64231575 |
Erectile dysfunction | 69.54 | 9.70 | 154 | 254550 | 12473 | 64231555 |
Generalised tonic-clonic seizure | 68.83 | 9.70 | 326 | 254378 | 39531 | 64204497 |
Anhedonia | 68.66 | 9.70 | 161 | 254543 | 13545 | 64230483 |
Drug dependence | 68.49 | 9.70 | 287 | 254417 | 33025 | 64211003 |
Obsessive thoughts | 67.76 | 9.70 | 45 | 254659 | 972 | 64243056 |
Dysarthria | 67.67 | 9.70 | 434 | 254270 | 58972 | 64185056 |
Euphoric mood | 67.49 | 9.70 | 105 | 254599 | 6486 | 64237542 |
Affective disorder | 66.23 | 9.70 | 104 | 254600 | 6476 | 64237552 |
Lower respiratory tract infection | 65.22 | 9.70 | 176 | 254528 | 94438 | 64149590 |
Bone marrow failure | 65.17 | 9.70 | 56 | 254648 | 47896 | 64196132 |
Product use issue | 64.95 | 9.70 | 343 | 254361 | 151372 | 64092656 |
Schizophrenia | 64.69 | 9.70 | 139 | 254565 | 11029 | 64232999 |
Foaming at mouth | 64.50 | 9.70 | 54 | 254650 | 1675 | 64242353 |
Activation syndrome | 64.47 | 9.70 | 28 | 254676 | 243 | 64243785 |
Platelet count decreased | 64.33 | 9.70 | 393 | 254311 | 167318 | 64076710 |
Negative thoughts | 63.85 | 9.70 | 48 | 254656 | 1270 | 64242758 |
Abnormal dreams | 63.59 | 9.70 | 132 | 254572 | 10224 | 64233804 |
Blister | 62.54 | 9.70 | 142 | 254562 | 80825 | 64163203 |
Speech disorder | 62.18 | 9.70 | 365 | 254339 | 48076 | 64195952 |
Impulsive behaviour | 62.10 | 9.70 | 64 | 254640 | 2599 | 64241429 |
Alcoholism | 62.06 | 9.70 | 72 | 254632 | 3345 | 64240683 |
Impaired healing | 62.01 | 9.70 | 89 | 254615 | 60384 | 64183644 |
Gestational diabetes | 61.40 | 9.70 | 92 | 254612 | 5498 | 64238530 |
Hallucinations, mixed | 60.01 | 9.70 | 95 | 254609 | 5957 | 64238071 |
Tardive dyskinesia | 59.93 | 9.70 | 120 | 254584 | 9058 | 64234970 |
Amenorrhoea | 59.88 | 9.70 | 99 | 254605 | 6440 | 64237588 |
Respiratory arrest | 59.06 | 9.70 | 385 | 254319 | 52600 | 64191428 |
Inflammation | 58.57 | 9.70 | 105 | 254599 | 65195 | 64178833 |
Muscle injury | 58.40 | 9.70 | 16 | 254688 | 26421 | 64217607 |
Hyperkalaemia | 58.40 | 9.70 | 204 | 254500 | 100925 | 64143103 |
Yawning | 58.27 | 9.70 | 44 | 254660 | 1172 | 64242856 |
Hepatic function abnormal | 58.06 | 9.70 | 103 | 254601 | 64210 | 64179818 |
Abulia | 55.94 | 9.70 | 38 | 254666 | 853 | 64243175 |
Flat affect | 55.25 | 9.70 | 51 | 254653 | 1806 | 64242222 |
Memory impairment | 54.68 | 9.70 | 548 | 254156 | 85134 | 64158894 |
Psychotic symptom | 54.65 | 9.70 | 54 | 254650 | 2084 | 64241944 |
Mental impairment | 54.44 | 9.70 | 165 | 254539 | 16178 | 64227850 |
Derealisation | 54.35 | 9.70 | 46 | 254658 | 1449 | 64242579 |
Persistent genital arousal disorder | 54.04 | 9.70 | 24 | 254680 | 221 | 64243807 |
Salivary hypersecretion | 53.96 | 9.70 | 136 | 254568 | 11977 | 64232051 |
Torticollis | 53.83 | 9.70 | 54 | 254650 | 2123 | 64241905 |
Ascites | 52.70 | 9.70 | 103 | 254601 | 61898 | 64182130 |
Tension | 52.24 | 9.70 | 70 | 254634 | 3770 | 64240258 |
Blood creatinine increased | 52.15 | 9.70 | 318 | 254386 | 135464 | 64108564 |
Pneumocystis jirovecii pneumonia | 51.91 | 9.70 | 22 | 254682 | 27612 | 64216416 |
Intentional product misuse | 51.88 | 9.70 | 474 | 254230 | 71821 | 64172207 |
Arthritis | 51.88 | 9.70 | 164 | 254540 | 83650 | 64160378 |
Genital hypoaesthesia | 51.50 | 9.70 | 21 | 254683 | 153 | 64243875 |
Blepharospasm | 51.33 | 9.70 | 65 | 254639 | 3310 | 64240718 |
Dyspnoea | 51.19 | 9.70 | 2319 | 252385 | 716355 | 63527673 |
Mood altered | 51.06 | 9.70 | 159 | 254545 | 15820 | 64228208 |
Disturbance in sexual arousal | 50.93 | 9.70 | 21 | 254683 | 158 | 64243870 |
Bipolar I disorder | 49.54 | 9.70 | 47 | 254657 | 1724 | 64242304 |
Interstitial lung disease | 49.43 | 9.70 | 208 | 254496 | 97524 | 64146504 |
Haemophagocytic lymphohistiocytosis | 48.85 | 9.70 | 6 | 254698 | 17603 | 64226425 |
Hypersomnia | 48.73 | 9.70 | 180 | 254524 | 19537 | 64224491 |
White blood cell count decreased | 47.77 | 9.70 | 396 | 254308 | 157441 | 64086587 |
Musculoskeletal pain | 47.60 | 9.70 | 163 | 254541 | 81131 | 64162897 |
Infarction | 47.59 | 9.70 | 68 | 254636 | 3892 | 64240136 |
Antipsychotic drug level increased | 47.59 | 9.70 | 78 | 254626 | 5037 | 64238991 |
Depersonalisation/derealisation disorder | 46.79 | 9.70 | 44 | 254660 | 1596 | 64242432 |
Alcohol poisoning | 46.70 | 9.70 | 70 | 254634 | 4185 | 64239843 |
Depressive symptom | 46.56 | 9.70 | 72 | 254632 | 4424 | 64239604 |
Drug reaction with eosinophilia and systemic symptoms | 46.13 | 9.70 | 90 | 254614 | 54127 | 64189901 |
Discomfort | 46.12 | 9.70 | 164 | 254540 | 80714 | 64163314 |
Basal cell carcinoma | 45.71 | 9.70 | 33 | 254671 | 30805 | 64213223 |
Lung disorder | 45.63 | 9.70 | 108 | 254596 | 60592 | 64183436 |
Bronchopulmonary aspergillosis | 45.18 | 9.70 | 10 | 254694 | 19075 | 64224953 |
Neutrophil count decreased | 45.05 | 9.70 | 155 | 254549 | 77041 | 64166987 |
Balance disorder | 44.82 | 9.70 | 518 | 254186 | 83408 | 64160620 |
Poisoning | 44.58 | 9.70 | 188 | 254516 | 21691 | 64222337 |
Dissociation | 44.23 | 9.70 | 57 | 254647 | 2954 | 64241074 |
Reversible cerebral vasoconstriction syndrome | 43.63 | 9.70 | 50 | 254654 | 2292 | 64241736 |
Burning mouth syndrome | 43.29 | 9.70 | 26 | 254678 | 468 | 64243560 |
Blood creatine phosphokinase increased | 43.06 | 9.70 | 386 | 254318 | 58172 | 64185856 |
Flashback | 42.88 | 9.70 | 21 | 254683 | 246 | 64243782 |
Intentional product use issue | 42.83 | 9.70 | 212 | 254492 | 95152 | 64148876 |
Confabulation | 42.42 | 9.70 | 25 | 254679 | 434 | 64243594 |
Dysphoria | 42.30 | 9.70 | 68 | 254636 | 4320 | 64239708 |
Gastrointestinal disorder | 42.29 | 9.70 | 196 | 254508 | 89513 | 64154515 |
Eye movement disorder | 42.03 | 9.70 | 89 | 254615 | 6990 | 64237038 |
Emotional poverty | 41.60 | 9.70 | 29 | 254675 | 680 | 64243348 |
Renal failure | 41.11 | 9.70 | 489 | 254215 | 181199 | 64062829 |
Product complaint | 41.06 | 9.70 | 122 | 254582 | 11832 | 64232196 |
Vertigo | 40.87 | 9.70 | 384 | 254320 | 58627 | 64185401 |
Drug resistance | 40.80 | 9.70 | 47 | 254657 | 35055 | 64208973 |
Pain in extremity | 40.77 | 9.70 | 899 | 253805 | 302186 | 63941842 |
Muscle tightness | 40.64 | 9.70 | 116 | 254588 | 10999 | 64233029 |
Hyponatraemic seizure | 40.39 | 9.70 | 25 | 254679 | 476 | 64243552 |
Herpes zoster | 40.37 | 9.70 | 168 | 254536 | 79019 | 64165009 |
Drug eruption | 40.28 | 9.70 | 50 | 254654 | 36086 | 64207942 |
Persistent depressive disorder | 40.27 | 9.70 | 33 | 254671 | 993 | 64243035 |
Ill-defined disorder | 40.26 | 9.70 | 70 | 254634 | 43982 | 64200046 |
Myelosuppression | 40.14 | 9.70 | 22 | 254682 | 23808 | 64220220 |
Formication | 39.94 | 9.70 | 66 | 254638 | 4291 | 64239737 |
Sensation of foreign body | 39.89 | 9.70 | 67 | 254637 | 4415 | 64239613 |
Violence-related symptom | 39.78 | 9.70 | 28 | 254676 | 667 | 64243361 |
Leukopenia | 39.45 | 9.70 | 236 | 254468 | 101006 | 64143022 |
Transplant rejection | 39.45 | 9.70 | 10 | 254694 | 17391 | 64226637 |
Haematotoxicity | 39.44 | 9.70 | 3 | 254701 | 12893 | 64231135 |
Cholecystitis chronic | 39.02 | 9.70 | 102 | 254602 | 9185 | 64234843 |
Psychomotor skills impaired | 39.02 | 9.70 | 61 | 254643 | 3784 | 64240244 |
Bipolar disorder | 38.99 | 9.70 | 84 | 254620 | 6677 | 64237351 |
Tumour lysis syndrome | 38.95 | 9.70 | 14 | 254690 | 19426 | 64224602 |
Pain | 38.93 | 9.70 | 1788 | 252916 | 551723 | 63692305 |
Thrombotic microangiopathy | 38.88 | 9.70 | 9 | 254695 | 16646 | 64227382 |
Abdominal discomfort | 38.88 | 9.70 | 497 | 254207 | 181825 | 64062203 |
Erythema | 38.76 | 9.70 | 513 | 254191 | 186557 | 64057471 |
Poverty of thought content | 38.68 | 9.70 | 13 | 254691 | 50 | 64243978 |
Fear | 38.55 | 9.70 | 170 | 254534 | 20001 | 64224027 |
Cycloplegia | 38.27 | 9.70 | 9 | 254695 | 3 | 64244025 |
Injection site pain | 38.18 | 9.70 | 270 | 254434 | 111138 | 64132890 |
Depression suicidal | 38.17 | 9.70 | 48 | 254656 | 2427 | 64241601 |
Death | 37.94 | 9.70 | 1540 | 253164 | 481165 | 63762863 |
Drowning | 37.90 | 9.70 | 28 | 254676 | 721 | 64243307 |
Uterine perforation | 37.88 | 9.70 | 76 | 254628 | 5744 | 64238284 |
Psoriatic arthropathy | 37.56 | 9.70 | 71 | 254633 | 43210 | 64200818 |
Abnormal weight gain | 37.49 | 9.70 | 45 | 254659 | 2168 | 64241860 |
Cogwheel rigidity | 37.28 | 9.70 | 51 | 254653 | 2802 | 64241226 |
Somnambulism | 36.95 | 9.70 | 70 | 254634 | 5071 | 64238957 |
Pruritus | 36.93 | 9.70 | 945 | 253759 | 311455 | 63932573 |
Disseminated intravascular coagulation | 36.86 | 9.70 | 44 | 254660 | 32304 | 64211724 |
Cough | 36.79 | 9.70 | 910 | 253794 | 301238 | 63942790 |
Disorganised speech | 35.53 | 9.70 | 38 | 254666 | 1612 | 64242416 |
Dysphemia | 35.21 | 9.70 | 52 | 254652 | 3067 | 64240961 |
Semen discolouration | 35.15 | 9.70 | 9 | 254695 | 8 | 64244020 |
Drug screen positive | 35.15 | 9.70 | 73 | 254631 | 5656 | 64238372 |
Self esteem decreased | 34.96 | 9.70 | 29 | 254675 | 888 | 64243140 |
Paraesthesia | 34.95 | 9.70 | 735 | 253969 | 133787 | 64110241 |
Skin ulcer | 34.87 | 9.70 | 76 | 254628 | 43898 | 64200130 |
Sleep disorder | 34.82 | 9.70 | 375 | 254329 | 59334 | 64184694 |
Bone erosion | 34.62 | 9.70 | 3 | 254701 | 11592 | 64232436 |
Clonus | 34.55 | 9.70 | 75 | 254629 | 5992 | 64238036 |
Syncope | 34.31 | 9.70 | 840 | 253864 | 156795 | 64087233 |
Ejaculation failure | 34.25 | 9.70 | 20 | 254684 | 341 | 64243687 |
Myelodysplastic syndrome | 34.19 | 9.70 | 35 | 254669 | 27544 | 64216484 |
Overweight | 33.84 | 9.70 | 53 | 254651 | 3293 | 64240735 |
Knee arthroplasty | 33.77 | 9.70 | 34 | 254670 | 26965 | 64217063 |
Food interaction | 33.77 | 9.70 | 35 | 254669 | 1431 | 64242597 |
Premature ejaculation | 33.36 | 9.70 | 12 | 254692 | 59 | 64243969 |
Lethargy | 33.11 | 9.70 | 435 | 254269 | 72159 | 64171869 |
Ideas of reference | 33.05 | 9.70 | 15 | 254689 | 146 | 64243882 |
Palpitations | 32.95 | 9.70 | 588 | 254116 | 103900 | 64140128 |
Nephropathy toxic | 32.81 | 9.70 | 14 | 254690 | 17500 | 64226528 |
Cytokine release syndrome | 32.59 | 9.70 | 21 | 254683 | 20808 | 64223220 |
Somatic symptom disorder of pregnancy | 32.32 | 9.70 | 13 | 254691 | 91 | 64243937 |
Palmar-plantar erythrodysaesthesia syndrome | 31.99 | 9.70 | 40 | 254664 | 28779 | 64215249 |
Injury | 31.89 | 9.70 | 350 | 254354 | 55642 | 64188386 |
Cardiac arrest | 31.76 | 9.70 | 815 | 253889 | 153249 | 64090779 |
Acute myeloid leukaemia | 31.67 | 9.70 | 37 | 254667 | 27426 | 64216602 |
Stiff person syndrome | 31.62 | 9.70 | 17 | 254687 | 245 | 64243783 |
Orgasm abnormal | 31.61 | 9.70 | 15 | 254689 | 163 | 64243865 |
Pneumonitis | 31.55 | 9.70 | 98 | 254606 | 50267 | 64193761 |
Hip arthroplasty | 31.44 | 9.70 | 23 | 254681 | 21328 | 64222700 |
Lymphadenopathy | 31.30 | 9.70 | 88 | 254616 | 46598 | 64197430 |
Sleep-related eating disorder | 31.19 | 9.70 | 24 | 254680 | 658 | 64243370 |
Tubulointerstitial nephritis | 31.18 | 9.70 | 46 | 254658 | 30863 | 64213165 |
Attention deficit hyperactivity disorder | 31.01 | 9.70 | 46 | 254658 | 2724 | 64241304 |
Negativism | 31.00 | 9.70 | 25 | 254679 | 735 | 64243293 |
Atrial fibrillation | 30.93 | 9.70 | 482 | 254222 | 170607 | 64073421 |
COVID-19 | 30.89 | 9.70 | 142 | 254562 | 64998 | 64179030 |
Haemoglobin decreased | 30.88 | 9.70 | 563 | 254141 | 194500 | 64049528 |
Multiple organ dysfunction syndrome | 30.87 | 9.70 | 254 | 254450 | 101159 | 64142869 |
Mutism | 30.66 | 9.70 | 39 | 254665 | 1995 | 64242033 |
Urinary incontinence | 30.65 | 9.70 | 246 | 254458 | 35905 | 64208123 |
Retroplacental haematoma | 30.53 | 9.70 | 13 | 254691 | 107 | 64243921 |
Heavy menstrual bleeding | 30.47 | 9.70 | 111 | 254593 | 11966 | 64232062 |
Dementia with Lewy bodies | 30.43 | 9.70 | 24 | 254680 | 683 | 64243345 |
Pregnancy with implant contraceptive | 30.27 | 9.70 | 33 | 254671 | 1431 | 64242597 |
Device dislocation | 30.09 | 9.70 | 164 | 254540 | 21014 | 64223014 |
Osteoporosis | 29.96 | 9.70 | 77 | 254627 | 42003 | 64202025 |
Platelet aggregation abnormal | 29.80 | 9.70 | 9 | 254695 | 22 | 64244006 |
Middle insomnia | 29.70 | 9.70 | 115 | 254589 | 12762 | 64231266 |
Adrenal insufficiency | 29.66 | 9.70 | 27 | 254677 | 22460 | 64221568 |
Cerebral vasoconstriction | 29.64 | 9.70 | 30 | 254674 | 1192 | 64242836 |
Action tremor | 29.58 | 9.70 | 19 | 254685 | 387 | 64243641 |
Prostate cancer | 29.58 | 9.70 | 21 | 254683 | 19774 | 64224254 |
Cytopenia | 29.57 | 9.70 | 12 | 254692 | 15459 | 64228569 |
Victim of chemical submission | 29.47 | 9.70 | 17 | 254687 | 283 | 64243745 |
Chronic kidney disease | 29.44 | 9.70 | 123 | 254581 | 57796 | 64186232 |
Graft versus host disease | 29.34 | 9.70 | 9 | 254695 | 13804 | 64230224 |
Urinary hesitation | 29.30 | 9.70 | 51 | 254653 | 3459 | 64240569 |
Cytomegalovirus viraemia | 29.29 | 9.70 | 4 | 254700 | 10824 | 64233204 |
Rash maculo-papular | 29.10 | 9.70 | 92 | 254612 | 46934 | 64197094 |
Schizoaffective disorder bipolar type | 29.06 | 9.70 | 13 | 254691 | 122 | 64243906 |
Pressure of speech | 28.83 | 9.70 | 27 | 254677 | 974 | 64243054 |
Anaphylactic shock | 28.81 | 9.70 | 47 | 254657 | 30281 | 64213747 |
Blood pressure fluctuation | 28.37 | 9.70 | 107 | 254597 | 51764 | 64192264 |
Pancreatic fibrosis | 28.37 | 9.70 | 12 | 254692 | 97 | 64243931 |
Nervousness | 28.34 | 9.70 | 207 | 254497 | 29349 | 64214679 |
Grandiosity | 28.31 | 9.70 | 21 | 254683 | 544 | 64243484 |
Device expulsion | 28.25 | 9.70 | 161 | 254543 | 20975 | 64223053 |
Tinnitus | 28.25 | 9.70 | 231 | 254473 | 33902 | 64210126 |
Proteinuria | 28.22 | 9.70 | 41 | 254663 | 27682 | 64216346 |
Injection site erythema | 28.13 | 9.70 | 164 | 254540 | 70636 | 64173392 |
Acute psychosis | 28.11 | 9.70 | 52 | 254652 | 3700 | 64240328 |
Urine sodium decreased | 28.07 | 9.70 | 16 | 254688 | 260 | 64243768 |
Male sexual dysfunction | 28.07 | 9.70 | 14 | 254690 | 171 | 64243857 |
Central vision loss | 27.92 | 9.70 | 8 | 254696 | 15 | 64244013 |
Posture abnormal | 27.80 | 9.70 | 49 | 254655 | 3357 | 64240671 |
Tongue spasm | 27.72 | 9.70 | 11 | 254693 | 74 | 64243954 |
Respiratory failure | 27.50 | 9.70 | 459 | 254245 | 160724 | 64083304 |
Psychiatric symptom | 27.49 | 9.70 | 70 | 254634 | 6203 | 64237825 |
Complication of device insertion | 27.46 | 9.70 | 61 | 254643 | 4951 | 64239077 |
Delusion of replacement | 27.34 | 9.70 | 13 | 254691 | 142 | 64243886 |
Rabbit syndrome | 27.14 | 9.70 | 17 | 254687 | 331 | 64243697 |
Physical assault | 27.12 | 9.70 | 32 | 254672 | 1514 | 64242514 |
Pathogen resistance | 26.95 | 9.70 | 8 | 254696 | 12535 | 64231493 |
Hereditary angioedema | 26.90 | 9.70 | 52 | 254652 | 3824 | 64240204 |
Irritable bowel syndrome | 26.90 | 9.70 | 68 | 254636 | 37301 | 64206727 |
Upper gastrointestinal haemorrhage | 26.84 | 9.70 | 234 | 254470 | 34986 | 64209042 |
Osteonecrosis of jaw | 26.75 | 9.70 | 75 | 254629 | 39750 | 64204278 |
Cataract | 26.60 | 9.70 | 108 | 254596 | 51154 | 64192874 |
Libido disorder | 26.58 | 9.70 | 15 | 254689 | 239 | 64243789 |
Dissociative disorder | 26.54 | 9.70 | 18 | 254686 | 403 | 64243625 |
Alanine aminotransferase increased | 26.39 | 9.70 | 388 | 254316 | 138643 | 64105385 |
Cognitive disorder | 26.35 | 9.70 | 333 | 254371 | 54754 | 64189274 |
Aspergillus infection | 26.34 | 9.70 | 16 | 254688 | 16363 | 64227665 |
Rheumatic fever | 26.19 | 9.70 | 3 | 254701 | 9291 | 64234737 |
Antidepressant drug level increased | 26.18 | 9.70 | 17 | 254687 | 353 | 64243675 |
Antisocial behaviour | 26.16 | 9.70 | 20 | 254684 | 543 | 64243485 |
Hypertonia | 26.10 | 9.70 | 69 | 254635 | 6256 | 64237772 |
Tearfulness | 25.74 | 9.70 | 57 | 254647 | 4616 | 64239412 |
Phobia | 25.60 | 9.70 | 17 | 254687 | 367 | 64243661 |
Respiratory tract infection | 25.45 | 9.70 | 70 | 254634 | 37337 | 64206691 |
Neoplasm progression | 25.45 | 9.70 | 80 | 254624 | 40884 | 64203144 |
Acute graft versus host disease | 25.43 | 9.70 | 3 | 254701 | 9081 | 64234947 |
Diffuse large B-cell lymphoma | 25.41 | 9.70 | 5 | 254699 | 10356 | 64233672 |
Cellulitis | 25.24 | 9.70 | 242 | 254462 | 93415 | 64150613 |
Device placement issue | 25.18 | 9.70 | 22 | 254682 | 724 | 64243304 |
Tachycardia | 25.15 | 9.70 | 771 | 253933 | 148808 | 64095220 |
Chorea | 25.01 | 9.70 | 35 | 254669 | 1965 | 64242063 |
Injection site pruritus | 24.84 | 9.70 | 72 | 254632 | 37754 | 64206274 |
Injection site bruising | 24.80 | 9.70 | 68 | 254636 | 36305 | 64207723 |
Drug dose titration not performed | 24.80 | 9.70 | 21 | 254683 | 662 | 64243366 |
Idiopathic intracranial hypertension | 24.75 | 9.70 | 40 | 254664 | 2553 | 64241475 |
Miosis | 24.74 | 9.70 | 111 | 254593 | 13155 | 64230873 |
Affect lability | 24.72 | 9.70 | 85 | 254619 | 8905 | 64235123 |
Febrile bone marrow aplasia | 24.51 | 9.70 | 7 | 254697 | 11248 | 64232780 |
Suppressed lactation | 24.45 | 9.70 | 15 | 254689 | 281 | 64243747 |
Dystonic tremor | 24.39 | 9.70 | 13 | 254691 | 184 | 64243844 |
Intermenstrual bleeding | 24.37 | 9.70 | 59 | 254645 | 5066 | 64238962 |
Persecutory delusion | 24.37 | 9.70 | 52 | 254652 | 4106 | 64239922 |
Hypercalcaemia | 24.33 | 9.70 | 55 | 254649 | 31361 | 64212667 |
Nystagmus | 24.29 | 9.70 | 85 | 254619 | 8983 | 64235045 |
Pseudomonas infection | 24.16 | 9.70 | 21 | 254683 | 17862 | 64226166 |
Mental status changes | 24.05 | 9.70 | 357 | 254347 | 60805 | 64183223 |
Swollen tongue | 23.97 | 9.70 | 227 | 254477 | 34727 | 64209301 |
Post-traumatic stress disorder | 23.97 | 9.70 | 52 | 254652 | 4153 | 64239875 |
Cardio-respiratory arrest | 23.76 | 9.70 | 532 | 254172 | 97861 | 64146167 |
Factor XIII deficiency | 23.73 | 9.70 | 10 | 254694 | 80 | 64243948 |
Morbid thoughts | 23.68 | 9.70 | 21 | 254683 | 705 | 64243323 |
Personality change | 23.41 | 9.70 | 81 | 254623 | 8512 | 64235516 |
Exposure during pregnancy | 23.39 | 9.70 | 434 | 254270 | 77241 | 64166787 |
Vanishing bile duct syndrome | 23.35 | 9.70 | 27 | 254677 | 1250 | 64242778 |
Creatinine renal clearance decreased | 23.31 | 9.70 | 14 | 254690 | 14407 | 64229621 |
Borderline personality disorder | 23.30 | 9.70 | 22 | 254682 | 802 | 64243226 |
Decreased interest | 23.23 | 9.70 | 45 | 254659 | 3315 | 64240713 |
Radiologically isolated syndrome | 23.09 | 9.70 | 6 | 254698 | 6 | 64244022 |
Phospholipidosis | 23.07 | 9.70 | 11 | 254693 | 121 | 64243907 |
Drug screen false positive | 23.02 | 9.70 | 24 | 254680 | 988 | 64243040 |
Hallucination, olfactory | 23 | 9.70 | 17 | 254687 | 438 | 64243590 |
Hyperuricaemia | 22.83 | 9.70 | 6 | 254698 | 10185 | 64233843 |
Hyponatraemic syndrome | 22.79 | 9.70 | 21 | 254683 | 742 | 64243286 |
Peritonitis | 22.65 | 9.70 | 40 | 254664 | 24983 | 64219045 |
Pleurothotonus | 22.64 | 9.70 | 36 | 254668 | 2266 | 64241762 |
Gaze palsy | 22.54 | 9.70 | 38 | 254666 | 2512 | 64241516 |
Headache | 22.41 | 9.70 | 2403 | 252301 | 527064 | 63716964 |
Ankylosing spondylitis | 22.37 | 9.70 | 3 | 254701 | 8231 | 64235797 |
Rheumatoid nodule | 22.32 | 9.70 | 11 | 254693 | 12640 | 64231388 |
Granulocytopenia | 22.28 | 9.70 | 91 | 254613 | 10349 | 64233679 |
Hepatic failure | 22.17 | 9.70 | 128 | 254576 | 55266 | 64188762 |
Feeling jittery | 22.15 | 9.70 | 92 | 254612 | 10543 | 64233485 |
Hallucination, gustatory | 22.14 | 9.70 | 9 | 254695 | 65 | 64243963 |
Muscle contractions involuntary | 22.14 | 9.70 | 43 | 254661 | 3174 | 64240854 |
Metabolic syndrome | 22.11 | 9.70 | 36 | 254668 | 2312 | 64241716 |
Heat stroke | 22.09 | 9.70 | 28 | 254676 | 1427 | 64242601 |
Diplopia | 22.07 | 9.70 | 181 | 254523 | 26584 | 64217444 |
Oedema peripheral | 22.03 | 9.70 | 647 | 254057 | 209670 | 64034358 |
Judgement impaired | 21.86 | 9.70 | 24 | 254680 | 1049 | 64242979 |
Environmental exposure | 21.84 | 9.70 | 15 | 254689 | 343 | 64243685 |
Therapeutic response unexpected | 21.74 | 9.70 | 128 | 254576 | 16873 | 64227155 |
Generalised anxiety disorder | 21.73 | 9.70 | 32 | 254672 | 1883 | 64242145 |
Embedded device | 21.70 | 9.70 | 39 | 254665 | 2713 | 64241315 |
Distractibility | 21.70 | 9.70 | 19 | 254685 | 627 | 64243401 |
Localised infection | 21.62 | 9.70 | 55 | 254649 | 30106 | 64213922 |
Amniotic fluid volume increased | 21.59 | 9.70 | 11 | 254693 | 141 | 64243887 |
Delusional disorder, unspecified type | 21.55 | 9.70 | 20 | 254684 | 713 | 64243315 |
Acute respiratory distress syndrome | 21.50 | 9.70 | 80 | 254624 | 38855 | 64205173 |
Suspected suicide | 21.38 | 9.70 | 79 | 254625 | 8575 | 64235453 |
Cystitis haemorrhagic | 21.37 | 9.70 | 3 | 254701 | 7953 | 64236075 |
Second primary malignancy | 21.35 | 9.70 | 11 | 254693 | 12326 | 64231702 |
Photophobia | 21.35 | 9.70 | 129 | 254575 | 17164 | 64226864 |
Psychogenic seizure | 21.23 | 9.70 | 31 | 254673 | 1810 | 64242218 |
Rapid eye movements sleep abnormal | 21.17 | 9.70 | 13 | 254691 | 244 | 64243784 |
Macrophages increased | 21.16 | 9.70 | 12 | 254692 | 193 | 64243835 |
Resting tremor | 21.14 | 9.70 | 27 | 254677 | 1387 | 64242641 |
Prader-Willi syndrome | 21.02 | 9.70 | 6 | 254698 | 11 | 64244017 |
Stress | 21.01 | 9.70 | 346 | 254358 | 60188 | 64183840 |
Blood bilirubin increased | 20.95 | 9.70 | 137 | 254567 | 57416 | 64186612 |
Unresponsive to stimuli | 20.95 | 9.70 | 297 | 254407 | 50096 | 64193932 |
Social anxiety disorder | 20.94 | 9.70 | 16 | 254688 | 434 | 64243594 |
Male orgasmic disorder | 20.93 | 9.70 | 8 | 254696 | 48 | 64243980 |
Postmortem blood drug level increased | 20.91 | 9.70 | 20 | 254684 | 741 | 64243287 |
Mitochondrial encephalomyopathy | 20.81 | 9.70 | 7 | 254697 | 27 | 64244001 |
Vision blurred | 20.77 | 9.70 | 485 | 254219 | 89831 | 64154197 |
Apallic syndrome | 20.68 | 9.70 | 21 | 254683 | 838 | 64243190 |
Coordination abnormal | 20.67 | 9.70 | 115 | 254589 | 14849 | 64229179 |
Polyneuropathy | 20.67 | 9.70 | 29 | 254675 | 19865 | 64224163 |
Coma | 20.61 | 9.70 | 472 | 254232 | 87143 | 64156885 |
Foreign body in reproductive tract | 20.60 | 9.70 | 16 | 254688 | 445 | 64243583 |
Fungal infection | 20.50 | 9.70 | 68 | 254636 | 34183 | 64209845 |
Aplastic anaemia | 20.49 | 9.70 | 15 | 254689 | 13905 | 64230123 |
Blood calcium decreased | 20.40 | 9.70 | 44 | 254660 | 25510 | 64218518 |
Enterocolitis | 20.38 | 9.70 | 11 | 254693 | 12007 | 64232021 |
Neutropenic sepsis | 20.35 | 9.70 | 38 | 254666 | 23234 | 64220794 |
Weight increased | 20.15 | 9.70 | 1033 | 253671 | 212315 | 64031713 |
Metabolic acidosis | 20.13 | 9.70 | 181 | 254523 | 70777 | 64173251 |
Heart rate decreased | 20.08 | 9.70 | 131 | 254573 | 54936 | 64189092 |
Urinary retention | 20.06 | 9.70 | 289 | 254415 | 48912 | 64195116 |
Inappropriate affect | 19.90 | 9.70 | 25 | 254679 | 1263 | 64242765 |
Parkinsonism hyperpyrexia syndrome | 19.88 | 9.70 | 12 | 254692 | 218 | 64243810 |
Gallbladder cholesterolosis | 19.81 | 9.70 | 17 | 254687 | 546 | 64243482 |
Loose associations | 19.77 | 9.70 | 8 | 254696 | 57 | 64243971 |
Diverticulitis | 19.63 | 9.70 | 82 | 254622 | 38536 | 64205492 |
Parasomnia | 19.59 | 9.70 | 16 | 254688 | 479 | 64243549 |
Liver disorder | 19.41 | 9.70 | 127 | 254577 | 53224 | 64190804 |
Cardiac failure congestive | 19.39 | 9.70 | 381 | 254323 | 130199 | 64113829 |
Tongue biting | 19.38 | 9.70 | 29 | 254675 | 1731 | 64242297 |
Morose | 19.36 | 9.70 | 7 | 254697 | 35 | 64243993 |
Oral candidiasis | 19.34 | 9.70 | 39 | 254665 | 23173 | 64220855 |
Transient psychosis | 19.31 | 9.70 | 8 | 254696 | 61 | 64243967 |
Impaired reasoning | 19.28 | 9.70 | 9 | 254695 | 94 | 64243934 |
Tuberculosis | 19.26 | 9.70 | 14 | 254690 | 13024 | 64231004 |
Dyspnoea exertional | 19.23 | 9.70 | 192 | 254512 | 73538 | 64170490 |
Lid lag | 19.20 | 9.70 | 8 | 254696 | 62 | 64243966 |
Panic disorder | 19.15 | 9.70 | 37 | 254667 | 2720 | 64241308 |
Parkinsonian gait | 19.07 | 9.70 | 20 | 254684 | 829 | 64243199 |
Lactic acidosis | 19.05 | 9.70 | 153 | 254551 | 61257 | 64182771 |
Personality disorder | 19.04 | 9.70 | 51 | 254653 | 4660 | 64239368 |
Muscle contracture | 19.00 | 9.70 | 32 | 254672 | 2113 | 64241915 |
Multiple sclerosis relapse | 18.97 | 9.70 | 247 | 254457 | 40888 | 64203140 |
Immunosuppressant drug level increased | 18.90 | 9.70 | 3 | 254701 | 7256 | 64236772 |
Neurotoxicity | 18.86 | 9.70 | 51 | 254653 | 27353 | 64216675 |
Hypotension | 18.73 | 9.70 | 1274 | 253430 | 379700 | 63864328 |
Perinatal depression | 18.71 | 9.70 | 13 | 254691 | 303 | 64243725 |
Plasma cell myeloma | 18.69 | 9.70 | 106 | 254598 | 45969 | 64198059 |
Urticaria | 18.63 | 9.70 | 441 | 254263 | 146876 | 64097152 |
Dermatillomania | 18.56 | 9.70 | 11 | 254693 | 193 | 64243835 |
Hyperacusis | 18.56 | 9.70 | 30 | 254674 | 1915 | 64242113 |
Conversion disorder | 18.47 | 9.70 | 28 | 254676 | 1691 | 64242337 |
Excessive masturbation | 18.36 | 9.70 | 8 | 254696 | 70 | 64243958 |
Eosinophilic pneumonia acute | 18.35 | 9.70 | 20 | 254684 | 867 | 64243161 |
Bleeding time prolonged | 18.29 | 9.70 | 23 | 254681 | 1163 | 64242865 |
Catastrophic reaction | 18.29 | 9.70 | 6 | 254698 | 21 | 64244007 |
Movement disorder | 18.26 | 9.70 | 149 | 254555 | 21851 | 64222177 |
Hyperbilirubinaemia | 18.21 | 9.70 | 35 | 254669 | 21170 | 64222858 |
Intracranial meningioma malignant | 18.15 | 9.70 | 4 | 254700 | 0 | 64244028 |
Hypoalbuminaemia | 18.12 | 9.70 | 26 | 254678 | 17648 | 64226380 |
Haemolytic anaemia | 18.11 | 9.70 | 22 | 254682 | 16031 | 64227997 |
Sexual activity increased | 18.07 | 9.70 | 6 | 254698 | 22 | 64244006 |
Pseudodementia | 18.07 | 9.70 | 6 | 254698 | 22 | 64244006 |
Hypocalcaemia | 18.07 | 9.70 | 94 | 254610 | 41659 | 64202369 |
Reduced facial expression | 18.03 | 9.70 | 31 | 254673 | 2082 | 64241946 |
Red blood cell sedimentation rate increased | 18.03 | 9.70 | 63 | 254641 | 31172 | 64212856 |
Glomerular filtration rate decreased | 17.97 | 9.70 | 31 | 254673 | 19541 | 64224487 |
Negative symptoms in schizophrenia | 17.97 | 9.70 | 9 | 254695 | 111 | 64243917 |
Disinhibition | 17.96 | 9.70 | 32 | 254672 | 2211 | 64241817 |
Dopamine dysregulation syndrome | 17.95 | 9.70 | 15 | 254689 | 464 | 64243564 |
Metastases to lymph nodes | 17.94 | 9.70 | 6 | 254698 | 8711 | 64235317 |
Biliary dyskinesia | 17.93 | 9.70 | 33 | 254671 | 2339 | 64241689 |
Polymenorrhoea | 17.93 | 9.70 | 20 | 254684 | 890 | 64243138 |
Aplasia | 17.82 | 9.70 | 3 | 254701 | 6950 | 64237078 |
Drop attacks | 17.79 | 9.70 | 21 | 254683 | 994 | 64243034 |
Feelings of worthlessness | 17.76 | 9.70 | 15 | 254689 | 471 | 64243557 |
Epstein-Barr virus infection | 17.69 | 9.70 | 14 | 254690 | 12474 | 64231554 |
Influenza | 17.63 | 9.70 | 305 | 254399 | 106226 | 64137802 |
Hypoaesthesia eye | 17.62 | 9.70 | 8 | 254696 | 78 | 64243950 |
Drug-device interaction | 17.62 | 9.70 | 8 | 254696 | 78 | 64243950 |
Pneumonia bacterial | 17.61 | 9.70 | 20 | 254684 | 15015 | 64229013 |
Incoherent | 17.60 | 9.70 | 65 | 254639 | 7053 | 64236975 |
Alanine aminotransferase abnormal | 17.59 | 9.70 | 3 | 254701 | 6885 | 64237143 |
Product use in unapproved indication | 17.59 | 9.70 | 547 | 254157 | 176071 | 64067957 |
Oxygen saturation decreased | 17.37 | 9.70 | 308 | 254396 | 106868 | 64137160 |
Blood pressure diastolic abnormal | 17.34 | 9.70 | 13 | 254691 | 11904 | 64232124 |
Aspartate aminotransferase increased | 17.33 | 9.70 | 351 | 254353 | 119437 | 64124591 |
BK virus infection | 17.31 | 9.70 | 4 | 254700 | 7408 | 64236620 |
Diaphragmatic rupture | 17.30 | 9.70 | 11 | 254693 | 220 | 64243808 |
Target skin lesion | 17.29 | 9.70 | 9 | 254695 | 121 | 64243907 |
Conjunctival abrasion | 17.24 | 9.70 | 5 | 254699 | 10 | 64244018 |
Lipidosis | 17.24 | 9.70 | 5 | 254699 | 10 | 64244018 |
Long QT syndrome | 17.22 | 9.70 | 52 | 254652 | 5087 | 64238941 |
Haemoptysis | 17.22 | 9.70 | 118 | 254586 | 48930 | 64195098 |
Kidney transplant rejection | 17.19 | 9.70 | 8 | 254696 | 9503 | 64234525 |
Ejection fraction decreased | 17.18 | 9.70 | 57 | 254647 | 28650 | 64215378 |
Caesarean section | 17.17 | 9.70 | 89 | 254615 | 11185 | 64232843 |
Metastases to lung | 17.14 | 9.70 | 21 | 254683 | 15243 | 64228785 |
Foetal death | 17.13 | 9.70 | 57 | 254647 | 5873 | 64238155 |
Depressed level of consciousness | 17.12 | 9.70 | 432 | 254272 | 81004 | 64163024 |
Rales | 17.05 | 9.70 | 21 | 254683 | 15208 | 64228820 |
Cardiogenic shock | 17.02 | 9.70 | 68 | 254636 | 32359 | 64211669 |
Agitated depression | 17.01 | 9.70 | 12 | 254692 | 287 | 64243741 |
Pulmonary haemorrhage | 16.98 | 9.70 | 16 | 254688 | 13093 | 64230935 |
Accommodation disorder | 16.98 | 9.70 | 15 | 254689 | 501 | 64243527 |
Aphasia | 16.97 | 9.70 | 241 | 254463 | 40665 | 64203363 |
Oral discomfort | 16.95 | 9.70 | 72 | 254632 | 8334 | 64235694 |
Communication disorder | 16.92 | 9.70 | 42 | 254662 | 3664 | 64240364 |
Cardiac failure acute | 16.80 | 9.70 | 24 | 254680 | 16320 | 64227708 |
Cold sweat | 16.79 | 9.70 | 117 | 254587 | 16338 | 64227690 |
Feeling drunk | 16.73 | 9.70 | 45 | 254659 | 4122 | 64239906 |
Erythromelalgia | 16.70 | 9.70 | 10 | 254694 | 179 | 64243849 |
Illness anxiety disorder | 16.59 | 9.70 | 11 | 254693 | 237 | 64243791 |
Therapeutic product effect incomplete | 16.58 | 9.70 | 298 | 254406 | 103184 | 64140844 |
Dysgraphia | 16.55 | 9.70 | 40 | 254664 | 3431 | 64240597 |
Urine chloride decreased | 16.54 | 9.70 | 8 | 254696 | 91 | 64243937 |
Suicide threat | 16.50 | 9.70 | 7 | 254697 | 57 | 64243971 |
Postural orthostatic tachycardia syndrome | 16.49 | 9.70 | 15 | 254689 | 521 | 64243507 |
Enuresis | 16.47 | 9.70 | 35 | 254669 | 2755 | 64241273 |
Eczema | 16.45 | 9.70 | 61 | 254643 | 29659 | 64214369 |
Ataxia | 16.45 | 9.70 | 146 | 254558 | 21938 | 64222090 |
Acute myocardial infarction | 16.39 | 9.70 | 186 | 254518 | 69532 | 64174496 |
Pre-eclampsia | 16.34 | 9.70 | 58 | 254646 | 6173 | 64237855 |
Serum serotonin decreased | 16.34 | 9.70 | 5 | 254699 | 13 | 64244015 |
Torsade de pointes | 16.30 | 9.70 | 121 | 254583 | 17242 | 64226786 |
Conjunctivitis | 16.28 | 9.70 | 35 | 254669 | 20319 | 64223709 |
Oral herpes | 16.18 | 9.70 | 40 | 254664 | 22112 | 64221916 |
Gout | 16.17 | 9.70 | 38 | 254666 | 21375 | 64222653 |
Metastases to liver | 16.14 | 9.70 | 45 | 254659 | 23896 | 64220132 |
Ejaculation delayed | 16.14 | 9.70 | 9 | 254695 | 140 | 64243888 |
Screaming | 16.11 | 9.70 | 40 | 254664 | 3489 | 64240539 |
Blood pressure increased | 16.08 | 9.70 | 539 | 254165 | 172013 | 64072015 |
Feeling guilty | 16.06 | 9.70 | 18 | 254686 | 805 | 64243223 |
Gastrointestinal motility disorder | 16.06 | 9.70 | 51 | 254653 | 5128 | 64238900 |
Drug abuser | 16.04 | 9.70 | 55 | 254649 | 5753 | 64238275 |
Substance abuse | 16.03 | 9.70 | 76 | 254628 | 9216 | 64234812 |
Glucose tolerance impaired in pregnancy | 15.93 | 9.70 | 4 | 254700 | 3 | 64244025 |
Joint hyperextension | 15.89 | 9.70 | 11 | 254693 | 255 | 64243773 |
Schizoaffective disorder | 15.86 | 9.70 | 25 | 254679 | 1562 | 64242466 |
Peripheral sensory neuropathy | 15.81 | 9.70 | 13 | 254691 | 11365 | 64232663 |
Cerebral infarction | 15.81 | 9.70 | 96 | 254608 | 40948 | 64203080 |
Rebound psychosis | 15.81 | 9.70 | 9 | 254695 | 146 | 64243882 |
Anorectal discomfort | 15.68 | 9.70 | 35 | 254669 | 2850 | 64241178 |
Product odour abnormal | 15.66 | 9.70 | 21 | 254683 | 1132 | 64242896 |
Colitis | 15.64 | 9.70 | 152 | 254552 | 58522 | 64185506 |
Collagen-vascular disease | 15.62 | 9.70 | 7 | 254697 | 66 | 64243962 |
Ophthalmic vein thrombosis | 15.60 | 9.70 | 10 | 254694 | 203 | 64243825 |
Death of relative | 15.60 | 9.70 | 10 | 254694 | 203 | 64243825 |
Periodic limb movement disorder | 15.59 | 9.70 | 9 | 254695 | 150 | 64243878 |
Hyperphagia | 15.57 | 9.70 | 30 | 254674 | 2201 | 64241827 |
Bladder dilatation | 15.56 | 9.70 | 27 | 254677 | 1827 | 64242201 |
Skin infection | 15.54 | 9.70 | 22 | 254682 | 15015 | 64229013 |
Cholangitis | 15.44 | 9.70 | 12 | 254692 | 10790 | 64233238 |
Brain injury | 15.41 | 9.70 | 79 | 254625 | 9886 | 64234142 |
Abortion missed | 15.39 | 9.70 | 21 | 254683 | 1151 | 64242877 |
Hepatocellular carcinoma | 15.29 | 9.70 | 7 | 254697 | 8396 | 64235632 |
COVID-19 pneumonia | 15.28 | 9.70 | 26 | 254678 | 16478 | 64227550 |
Injection site swelling | 15.27 | 9.70 | 98 | 254606 | 41255 | 64202773 |
Soliloquy | 15.26 | 9.70 | 15 | 254689 | 575 | 64243453 |
Marital problem | 15.26 | 9.70 | 10 | 254694 | 211 | 64243817 |
CYP3A4 polymorphism | 15.26 | 9.70 | 7 | 254697 | 70 | 64243958 |
Alcohol interaction | 15.19 | 9.70 | 45 | 254659 | 4356 | 64239672 |
Maternal exposure during breast feeding | 15.18 | 9.70 | 28 | 254676 | 1988 | 64242040 |
Mobility decreased | 15.11 | 9.70 | 243 | 254461 | 85597 | 64158431 |
Selective mutism | 15.09 | 9.70 | 7 | 254697 | 72 | 64243956 |
Menopausal disorder | 15.04 | 9.70 | 6 | 254698 | 41 | 64243987 |
Rhinovirus infection | 15.03 | 9.70 | 3 | 254701 | 6153 | 64237875 |
Therapy non-responder | 15.03 | 9.70 | 177 | 254527 | 65722 | 64178306 |
Fear of weight gain | 14.92 | 9.70 | 5 | 254699 | 19 | 64244009 |
Polyarthritis | 14.92 | 9.70 | 10 | 254694 | 9705 | 64234323 |
Dementia Alzheimer's type | 14.92 | 9.70 | 19 | 254685 | 973 | 64243055 |
Oesophageal pain | 14.92 | 9.70 | 37 | 254667 | 3226 | 64240802 |
Pulmonary tuberculosis | 14.89 | 9.70 | 5 | 254699 | 7239 | 64236789 |
Coagulopathy | 14.88 | 9.70 | 70 | 254634 | 31850 | 64212178 |
Metastases to bone | 14.85 | 9.70 | 37 | 254667 | 20398 | 64223630 |
Unintended pregnancy | 14.82 | 9.70 | 36 | 254668 | 3098 | 64240930 |
Pharyngeal swelling | 14.80 | 9.70 | 52 | 254652 | 5507 | 64238521 |
Complication of device removal | 14.79 | 9.70 | 37 | 254667 | 3243 | 64240785 |
Optic ischaemic neuropathy | 14.77 | 9.70 | 32 | 254672 | 2553 | 64241475 |
Postpartum haemorrhage | 14.74 | 9.70 | 23 | 254681 | 1424 | 64242604 |
Differential white blood cell count abnormal | 14.72 | 9.70 | 26 | 254678 | 1784 | 64242244 |
Panic reaction | 14.69 | 9.70 | 42 | 254662 | 3985 | 64240043 |
Tenosynovitis | 14.69 | 9.70 | 15 | 254689 | 11818 | 64232210 |
Head injury | 14.64 | 9.70 | 196 | 254508 | 32646 | 64211382 |
Reflexes abnormal | 14.60 | 9.70 | 17 | 254687 | 793 | 64243235 |
Daydreaming | 14.60 | 9.70 | 17 | 254687 | 793 | 64243235 |
Body mass index increased | 14.58 | 9.70 | 24 | 254680 | 1555 | 64242473 |
Skin toxicity | 14.57 | 9.70 | 4 | 254700 | 6598 | 64237430 |
Morning sickness | 14.57 | 9.70 | 13 | 254691 | 440 | 64243588 |
Renal injury | 14.57 | 9.70 | 24 | 254680 | 15405 | 64228623 |
Jaundice | 14.53 | 9.70 | 122 | 254582 | 48390 | 64195638 |
Obsessive rumination | 14.51 | 9.70 | 4 | 254700 | 6 | 64244022 |
Partner stress | 14.50 | 9.70 | 11 | 254693 | 295 | 64243733 |
Menopause | 14.50 | 9.70 | 25 | 254679 | 1683 | 64242345 |
Diarrhoea | 14.46 | 9.70 | 2573 | 252131 | 720131 | 63523897 |
Paraneoplastic rash | 14.44 | 9.70 | 7 | 254697 | 80 | 64243948 |
Hypersexuality | 14.37 | 9.70 | 23 | 254681 | 1456 | 64242572 |
Vascular dementia | 14.33 | 9.70 | 17 | 254687 | 809 | 64243219 |
Gallbladder injury | 14.22 | 9.70 | 20 | 254684 | 1128 | 64242900 |
Asphyxia | 14.22 | 9.70 | 75 | 254629 | 9491 | 64234537 |
Petit mal epilepsy | 14.21 | 9.70 | 48 | 254656 | 4984 | 64239044 |
Bronchitis | 14.18 | 9.70 | 324 | 254380 | 108419 | 64135609 |
Subchorionic haemorrhage | 14.09 | 9.70 | 8 | 254696 | 129 | 64243899 |
Menstruation irregular | 14.05 | 9.70 | 44 | 254660 | 4391 | 64239637 |
Pyromania | 14.00 | 9.70 | 5 | 254699 | 24 | 64244004 |
Basophil count abnormal | 14.00 | 9.70 | 5 | 254699 | 24 | 64244004 |
Multiple sclerosis | 13.99 | 9.70 | 125 | 254579 | 18816 | 64225212 |
Cardiotoxicity | 13.96 | 9.70 | 12 | 254692 | 10262 | 64233766 |
Water intoxication | 13.95 | 9.70 | 16 | 254688 | 734 | 64243294 |
Helplessness | 13.89 | 9.70 | 11 | 254693 | 315 | 64243713 |
Tunnel vision | 13.86 | 9.70 | 19 | 254685 | 1046 | 64242982 |
Dependence | 13.86 | 9.70 | 28 | 254676 | 2127 | 64241901 |
Levator syndrome | 13.83 | 9.70 | 5 | 254699 | 25 | 64244003 |
Skin necrosis | 13.80 | 9.70 | 22 | 254682 | 14307 | 64229721 |
Device related infection | 13.79 | 9.70 | 68 | 254636 | 30558 | 64213470 |
Anal incontinence | 13.76 | 9.70 | 105 | 254599 | 15091 | 64228937 |
Haemorrhagic hepatic cyst | 13.72 | 9.70 | 6 | 254698 | 53 | 64243975 |
Obsessive-compulsive symptom | 13.72 | 9.70 | 8 | 254696 | 136 | 64243892 |
Blood parathyroid hormone decreased | 13.62 | 9.70 | 6 | 254698 | 7360 | 64236668 |
Overconfidence | 13.62 | 9.70 | 3 | 254701 | 0 | 64244028 |
Postictal headache | 13.62 | 9.70 | 3 | 254701 | 0 | 64244028 |
Olfactory nerve disorder | 13.62 | 9.70 | 3 | 254701 | 0 | 64244028 |
Arterial ligation | 13.62 | 9.70 | 3 | 254701 | 0 | 64244028 |
Anaplastic large cell lymphoma T- and null-cell types stage IV | 13.62 | 9.70 | 3 | 254701 | 0 | 64244028 |
Respiratory tract congestion | 13.61 | 9.70 | 27 | 254677 | 16138 | 64227890 |
Oropharyngeal pain | 13.58 | 9.70 | 258 | 254446 | 88609 | 64155419 |
Hyporesponsive to stimuli | 13.58 | 9.70 | 25 | 254679 | 1772 | 64242256 |
Therapeutic response decreased | 13.57 | 9.70 | 136 | 254568 | 52052 | 64191976 |
Haematuria | 13.57 | 9.70 | 163 | 254541 | 60308 | 64183720 |
Hypochloraemia | 13.52 | 9.70 | 27 | 254677 | 2034 | 64241994 |
Herpes simplex | 13.49 | 9.70 | 13 | 254691 | 10523 | 64233505 |
Transaminases increased | 13.42 | 9.70 | 112 | 254592 | 44482 | 64199546 |
Female orgasmic disorder | 13.37 | 9.70 | 5 | 254699 | 28 | 64244000 |
Herbal interaction | 13.36 | 9.70 | 12 | 254692 | 410 | 64243618 |
Somatic delusion | 13.31 | 9.70 | 15 | 254689 | 675 | 64243353 |
Compulsions | 13.31 | 9.70 | 11 | 254693 | 335 | 64243693 |
Hepatitis B | 13.26 | 9.70 | 7 | 254697 | 7738 | 64236290 |
Electrocardiogram T wave abnormal | 13.23 | 9.70 | 36 | 254668 | 3320 | 64240708 |
Breast enlargement | 13.22 | 9.70 | 21 | 254683 | 1321 | 64242707 |
Exposure via breast milk | 13.21 | 9.70 | 16 | 254688 | 778 | 64243250 |
Pulmonary microemboli | 13.18 | 9.70 | 4 | 254700 | 10 | 64244018 |
Renal tubular necrosis | 13.16 | 9.70 | 44 | 254660 | 22066 | 64221962 |
Back pain | 13.06 | 9.70 | 832 | 253872 | 249339 | 63994689 |
Blood pressure systolic abnormal | 13.04 | 9.70 | 12 | 254692 | 9930 | 64234098 |
Temporomandibular joint syndrome | 13.01 | 9.70 | 36 | 254668 | 3352 | 64240676 |
Schizophreniform disorder | 12.99 | 9.70 | 8 | 254696 | 151 | 64243877 |
Gait deviation | 12.91 | 9.70 | 6 | 254698 | 62 | 64243966 |
Epistaxis | 12.90 | 9.70 | 292 | 254412 | 97839 | 64146189 |
Tongue haematoma | 12.87 | 9.70 | 9 | 254695 | 212 | 64243816 |
Product taste abnormal | 12.85 | 9.70 | 26 | 254678 | 1977 | 64242051 |
Concomitant disease aggravated | 12.83 | 9.70 | 16 | 254688 | 11526 | 64232502 |
Maternal drugs affecting foetus | 12.83 | 9.70 | 23 | 254681 | 1597 | 64242431 |
Neoplasm malignant | 12.81 | 9.70 | 52 | 254652 | 24636 | 64219392 |
Lack of spontaneous speech | 12.80 | 9.70 | 9 | 254695 | 214 | 64243814 |
Substance use disorder | 12.75 | 9.70 | 11 | 254693 | 356 | 64243672 |
Squamous cell carcinoma | 12.71 | 9.70 | 22 | 254682 | 13847 | 64230181 |
Feeling of despair | 12.68 | 9.70 | 30 | 254674 | 2538 | 64241490 |
Blood triglycerides increased | 12.68 | 9.70 | 122 | 254582 | 18744 | 64225284 |
Change of bowel habit | 12.61 | 9.70 | 29 | 254675 | 2409 | 64241619 |
Abnormal uterine bleeding | 12.57 | 9.70 | 16 | 254688 | 819 | 64243209 |
Dermatitis acneiform | 12.56 | 9.70 | 9 | 254695 | 8434 | 64235594 |
Intestinal perforation | 12.53 | 9.70 | 26 | 254678 | 15287 | 64228741 |
Gastrointestinal perforation | 12.52 | 9.70 | 3 | 254701 | 5421 | 64238607 |
Anuria | 12.52 | 9.70 | 36 | 254668 | 18928 | 64225100 |
Atrial septal defect | 12.50 | 9.70 | 23 | 254681 | 1630 | 64242398 |
Vomiting | 12.43 | 9.70 | 2412 | 252292 | 548705 | 63695323 |
Genital anaesthesia | 12.42 | 9.70 | 4 | 254700 | 13 | 64244015 |
Blood lactate dehydrogenase increased | 12.41 | 9.70 | 78 | 254626 | 33000 | 64211028 |
Psychiatric decompensation | 12.41 | 9.70 | 29 | 254675 | 2434 | 64241594 |
Rhabdomyolysis | 12.41 | 9.70 | 461 | 254243 | 91265 | 64152763 |
Libido increased | 12.41 | 9.70 | 24 | 254680 | 1766 | 64242262 |
Abnormal loss of weight | 12.39 | 9.70 | 60 | 254644 | 7340 | 64236688 |
Orthostatic hypotension | 12.33 | 9.70 | 256 | 254448 | 46482 | 64197546 |
Energy increased | 12.32 | 9.70 | 31 | 254673 | 2727 | 64241301 |
Malpositioned teeth | 12.31 | 9.70 | 5 | 254699 | 36 | 64243992 |
Fear of injection | 12.29 | 9.70 | 4 | 254700 | 5908 | 64238120 |
Reflux laryngitis | 12.27 | 9.70 | 6 | 254698 | 70 | 64243958 |
Acute generalised exanthematous pustulosis | 12.25 | 9.70 | 23 | 254681 | 14035 | 64229993 |
Implant site irritation | 12.22 | 9.70 | 7 | 254697 | 115 | 64243913 |
Alcohol use | 12.21 | 9.70 | 43 | 254661 | 4559 | 64239469 |
Serositis | 12.20 | 9.70 | 15 | 254689 | 741 | 64243287 |
Alveolar bone resorption | 12.20 | 9.70 | 6 | 254698 | 71 | 64243957 |
Bankruptcy | 12.20 | 9.70 | 5 | 254699 | 37 | 64243991 |
Hepatic steatosis | 12.19 | 9.70 | 181 | 254523 | 30826 | 64213202 |
Blood ethanol increased | 12.18 | 9.70 | 14 | 254690 | 644 | 64243384 |
Ectopic pregnancy | 12.12 | 9.70 | 22 | 254682 | 1542 | 64242486 |
Increased appetite | 12.09 | 9.70 | 75 | 254629 | 10071 | 64233957 |
Trichotillomania | 12.04 | 9.70 | 8 | 254696 | 173 | 64243855 |
Hepatic lesion | 12.00 | 9.70 | 4 | 254700 | 5820 | 64238208 |
Head discomfort | 11.99 | 9.70 | 84 | 254620 | 11750 | 64232278 |
Pelvic pain | 11.98 | 9.70 | 79 | 254625 | 10831 | 64233197 |
Haematochezia | 11.98 | 9.70 | 187 | 254517 | 66186 | 64177842 |
Gait disturbance | 11.94 | 9.70 | 811 | 253893 | 171344 | 64072684 |
Blood urea increased | 11.93 | 9.70 | 114 | 254590 | 44039 | 64199989 |
Amniotic cavity infection | 11.92 | 9.70 | 15 | 254689 | 759 | 64243269 |
Compulsive sexual behaviour | 11.88 | 9.70 | 9 | 254695 | 241 | 64243787 |
Drooling | 11.86 | 9.70 | 47 | 254657 | 5272 | 64238756 |
Atrioventricular dissociation | 11.81 | 9.70 | 10 | 254694 | 315 | 64243713 |
Lymphomatoid papulosis | 11.79 | 9.70 | 10 | 254694 | 316 | 64243712 |
Hypersensitivity vasculitis | 11.74 | 9.70 | 6 | 254698 | 6755 | 64237273 |
Alcohol abuse | 11.74 | 9.70 | 44 | 254660 | 4808 | 64239220 |
Oesophageal ulcer haemorrhage | 11.72 | 9.70 | 13 | 254691 | 575 | 64243453 |
Drug level increased | 11.70 | 9.70 | 195 | 254509 | 34001 | 64210027 |
Suspiciousness | 11.66 | 9.70 | 13 | 254691 | 578 | 64243450 |
Lactate pyruvate ratio increased | 11.64 | 9.70 | 6 | 254698 | 79 | 64243949 |
Periorbital swelling | 11.62 | 9.70 | 24 | 254680 | 1852 | 64242176 |
Breast discomfort | 11.60 | 9.70 | 10 | 254694 | 323 | 64243705 |
Vasodilation procedure | 11.55 | 9.70 | 5 | 254699 | 43 | 64243985 |
Hippocampal atrophy | 11.55 | 9.70 | 3 | 254701 | 3 | 64244025 |
Nasal cavity packing | 11.55 | 9.70 | 3 | 254701 | 3 | 64244025 |
Barbiturates positive | 11.55 | 9.70 | 3 | 254701 | 3 | 64244025 |
Large intestine perforation | 11.54 | 9.70 | 20 | 254684 | 12584 | 64231444 |
Vaginal haemorrhage | 11.51 | 9.70 | 122 | 254582 | 19222 | 64224806 |
Mallory-Weiss syndrome | 11.50 | 9.70 | 29 | 254675 | 2554 | 64241474 |
Pneumothorax | 11.50 | 9.70 | 53 | 254651 | 24245 | 64219783 |
Ejaculation disorder | 11.47 | 9.70 | 12 | 254692 | 496 | 64243532 |
Gambling disorder | 11.46 | 9.70 | 24 | 254680 | 1870 | 64242158 |
Polymenorrhagia | 11.45 | 9.70 | 5 | 254699 | 44 | 64243984 |
Lymphoproliferative disorder | 11.44 | 9.70 | 3 | 254701 | 5100 | 64238928 |
Dry mouth | 11.40 | 9.70 | 316 | 254388 | 60102 | 64183926 |
Serum ferritin increased | 11.37 | 9.70 | 10 | 254694 | 8458 | 64235570 |
Aphthous ulcer | 11.35 | 9.70 | 21 | 254683 | 12885 | 64231143 |
Unmasking of previously unidentified disease | 11.31 | 9.70 | 22 | 254682 | 1625 | 64242403 |
Panniculitis | 11.31 | 9.70 | 11 | 254693 | 8868 | 64235160 |
Grip strength decreased | 11.29 | 9.70 | 18 | 254686 | 11706 | 64232322 |
Delusional perception | 11.27 | 9.70 | 10 | 254694 | 336 | 64243692 |
Purple glove syndrome | 11.26 | 9.70 | 9 | 254695 | 261 | 64243767 |
Vanishing twin syndrome | 11.25 | 9.70 | 6 | 254698 | 85 | 64243943 |
Sleep inertia | 11.23 | 9.70 | 4 | 254700 | 19 | 64244009 |
Tongue discolouration | 11.21 | 9.70 | 34 | 254670 | 3334 | 64240694 |
Hippocampal sclerosis | 11.19 | 9.70 | 7 | 254697 | 136 | 64243892 |
Poor personal hygiene | 11.14 | 9.70 | 12 | 254692 | 513 | 64243515 |
Gastric hypomotility | 11.14 | 9.70 | 7 | 254697 | 137 | 64243891 |
Maternal condition affecting foetus | 11.14 | 9.70 | 7 | 254697 | 137 | 64243891 |
Drug tolerance increased | 11.14 | 9.70 | 13 | 254691 | 608 | 64243420 |
Oedema | 11.13 | 9.70 | 277 | 254427 | 91658 | 64152370 |
Liver function test increased | 11.13 | 9.70 | 74 | 254630 | 30896 | 64213132 |
Abscess | 11.10 | 9.70 | 39 | 254665 | 19265 | 64224763 |
Shoplifting | 11.09 | 9.70 | 3 | 254701 | 4 | 64244024 |
Metastases to central nervous system | 11.06 | 9.70 | 24 | 254680 | 13888 | 64230140 |
Duplicate therapy error | 11.03 | 9.70 | 8 | 254696 | 200 | 64243828 |
Obesity | 11.01 | 9.70 | 127 | 254577 | 20435 | 64223593 |
Autoscopy | 10.99 | 9.70 | 5 | 254699 | 49 | 64243979 |
Musculoskeletal stiffness | 10.98 | 9.70 | 387 | 254317 | 122819 | 64121209 |
Gun shot wound | 10.96 | 9.70 | 17 | 254687 | 1047 | 64242981 |
Multiple-drug resistance | 10.95 | 9.70 | 6 | 254698 | 6496 | 64237532 |
Rash erythematous | 10.94 | 9.70 | 131 | 254573 | 48502 | 64195526 |
Osteomyelitis | 10.90 | 9.70 | 64 | 254640 | 27523 | 64216505 |
Platelet aggregation decreased | 10.90 | 9.70 | 5 | 254699 | 50 | 64243978 |
Dyspraxia | 10.89 | 9.70 | 9 | 254695 | 274 | 64243754 |
Delusion of reference | 10.88 | 9.70 | 7 | 254697 | 143 | 64243885 |
Renal tubular disorder | 10.88 | 9.70 | 5 | 254699 | 5982 | 64238046 |
Hepatotoxicity | 10.87 | 9.70 | 103 | 254601 | 39859 | 64204169 |
Body temperature decreased | 10.87 | 9.70 | 59 | 254645 | 25869 | 64218159 |
Slow response to stimuli | 10.87 | 9.70 | 21 | 254683 | 1544 | 64242484 |
Premature baby | 10.86 | 9.70 | 33 | 254671 | 3239 | 64240789 |
Blood pressure systolic increased | 10.83 | 9.70 | 134 | 254570 | 49319 | 64194709 |
Respiratory dyskinesia | 10.81 | 9.70 | 5 | 254699 | 51 | 64243977 |
Gastrointestinal haemorrhage | 10.81 | 9.70 | 420 | 254284 | 131892 | 64112136 |
Product monitoring error | 10.80 | 9.70 | 4 | 254700 | 5450 | 64238578 |
Cytomegalovirus chorioretinitis | 10.80 | 9.70 | 3 | 254701 | 4909 | 64239119 |
Implant site extravasation | 10.77 | 9.70 | 14 | 254690 | 732 | 64243296 |
Myocardial infarction | 10.74 | 9.70 | 540 | 254164 | 165281 | 64078747 |
Mixed dementia | 10.70 | 9.70 | 9 | 254695 | 281 | 64243747 |
Incontinence | 10.67 | 9.70 | 83 | 254621 | 11998 | 64232030 |
Catheterisation cardiac | 10.67 | 9.70 | 3 | 254701 | 4870 | 64239158 |
Merycism | 10.63 | 9.70 | 8 | 254696 | 212 | 64243816 |
Cardiac failure chronic | 10.62 | 9.70 | 12 | 254692 | 9029 | 64234999 |
Transfusion | 10.58 | 9.70 | 36 | 254668 | 17958 | 64226070 |
Coprolalia | 10.56 | 9.70 | 5 | 254699 | 54 | 64243974 |
Dementia | 10.56 | 9.70 | 127 | 254577 | 20639 | 64223389 |
Appetite disorder | 10.54 | 9.70 | 52 | 254652 | 6409 | 64237619 |
Amnestic disorder | 10.52 | 9.70 | 12 | 254692 | 547 | 64243481 |
Hypokinesia | 10.51 | 9.70 | 106 | 254598 | 16490 | 64227538 |
Deprescribing error | 10.46 | 9.70 | 4 | 254700 | 24 | 64244004 |
Sickle cell anaemia with crisis | 10.41 | 9.70 | 4 | 254700 | 5328 | 64238700 |
Nervous system disorder | 10.40 | 9.70 | 138 | 254566 | 22940 | 64221088 |
Stoma site infection | 10.38 | 9.70 | 18 | 254686 | 1217 | 64242811 |
Bone pain | 10.38 | 9.70 | 129 | 254575 | 47443 | 64196585 |
Self-medication | 10.37 | 9.70 | 38 | 254666 | 4107 | 64239921 |
Night sweats | 10.36 | 9.70 | 200 | 254504 | 35846 | 64208182 |
Tendonitis | 10.35 | 9.70 | 43 | 254661 | 20239 | 64223789 |
Painful erection | 10.35 | 9.70 | 7 | 254697 | 156 | 64243872 |
Foetal exposure during pregnancy | 10.34 | 9.70 | 40 | 254664 | 4436 | 64239592 |
Factor XIII Inhibition | 10.33 | 9.70 | 4 | 254700 | 25 | 64244003 |
Sciatica | 10.32 | 9.70 | 43 | 254661 | 20221 | 64223807 |
Retroperitoneal fibrosis | 10.25 | 9.70 | 12 | 254692 | 563 | 64243465 |
Sluggishness | 10.24 | 9.70 | 47 | 254657 | 5623 | 64238405 |
Acanthosis nigricans | 10.20 | 9.70 | 7 | 254697 | 160 | 64243868 |
Poverty of speech | 10.18 | 9.70 | 12 | 254692 | 567 | 64243461 |
Hypersensitivity pneumonitis | 10.18 | 9.70 | 32 | 254672 | 3200 | 64240828 |
Blood citric acid increased | 10.18 | 9.70 | 5 | 254699 | 59 | 64243969 |
Stubbornness | 10.15 | 9.70 | 9 | 254695 | 302 | 64243726 |
Premature labour | 10.15 | 9.70 | 58 | 254646 | 7562 | 64236466 |
Snoring | 10.14 | 9.70 | 41 | 254663 | 4641 | 64239387 |
Pelvic inflammatory disease | 10.14 | 9.70 | 18 | 254686 | 1240 | 64242788 |
Oesophageal candidiasis | 10.14 | 9.70 | 10 | 254694 | 8007 | 64236021 |
Pneumatosis intestinalis | 10.08 | 9.70 | 4 | 254700 | 5225 | 64238803 |
Alcohol intolerance | 10.08 | 9.70 | 10 | 254694 | 388 | 64243640 |
Seizure like phenomena | 10.08 | 9.70 | 21 | 254683 | 1631 | 64242397 |
Right ventricular failure | 10.06 | 9.70 | 47 | 254657 | 21424 | 64222604 |
Hypokalaemia | 10.06 | 9.70 | 583 | 254121 | 121320 | 64122708 |
Antidepressant drug level decreased | 10.03 | 9.70 | 3 | 254701 | 7 | 64244021 |
Pancreatic enzymes decreased | 10.03 | 9.70 | 3 | 254701 | 7 | 64244021 |
Logorrhoea | 9.98 | 9.70 | 37 | 254667 | 4022 | 64240006 |
Coronary arterial stent insertion | 9.96 | 9.70 | 5 | 254699 | 5687 | 64238341 |
Premature rupture of membranes | 9.95 | 9.70 | 35 | 254669 | 3709 | 64240319 |
Gallbladder disorder | 9.95 | 9.70 | 107 | 254597 | 16923 | 64227105 |
Anal abscess | 9.92 | 9.70 | 9 | 254695 | 7499 | 64236529 |
Medication error | 9.90 | 9.70 | 263 | 254441 | 49703 | 64194325 |
Exposure via ingestion | 9.89 | 9.70 | 42 | 254662 | 4860 | 64239168 |
Leukaemoid reaction | 9.88 | 9.70 | 9 | 254695 | 313 | 64243715 |
Pulmonary mass | 9.88 | 9.70 | 55 | 254649 | 23961 | 64220067 |
Skin fissures | 9.76 | 9.70 | 16 | 254688 | 10290 | 64233738 |
Loss of personal independence in daily activities | 9.76 | 9.70 | 364 | 254340 | 72090 | 64171938 |
Flight of ideas | 9.73 | 9.70 | 13 | 254691 | 698 | 64243330 |
Visceral congestion | 9.71 | 9.70 | 14 | 254690 | 808 | 64243220 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Premature baby | 28.84 | 19.20 | 34 | 2128 | 3796 | 78720 |
Agitation neonatal | 25.34 | 19.20 | 52 | 2110 | 579 | 81937 |
Human herpesvirus 6 infection | 20.80 | 19.20 | 15 | 2147 | 45 | 82471 |
Source | Code | Description |
---|---|---|
ATC | N06AB06 | NERVOUS SYSTEM PSYCHOANALEPTICS ANTIDEPRESSANTS Selective serotonin reuptake inhibitors |
FDA MoA | N0000000109 | Serotonin Uptake Inhibitors |
CHEBI has role | CHEBI:35469 | antidepressants |
CHEBI has role | CHEBI:50949 | SSRI |
FDA EPC | N0000175696 | Serotonin Reuptake Inhibitor |
FDA MoA | N0000182137 | Cytochrome P450 2D6 Inhibitors |
MeSH PA | D000928 | Antidepressive Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D049990 | Membrane Transport Modulators |
MeSH PA | D018377 | Neurotransmitter Agents |
MeSH PA | D014179 | Neurotransmitter Uptake Inhibitors |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D018490 | Serotonin Agents |
MeSH PA | D017367 | Serotonin Uptake Inhibitors |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Premenstrual dysphoric disorder | indication | 596004 | |
Social phobia | indication | 25501002 | DOID:11257 |
Depressive disorder | indication | 35489007 | |
Posttraumatic stress disorder | indication | 47505003 | DOID:2055 |
Obsessive-compulsive disorder | indication | 191736004 | DOID:10933 |
Panic disorder | indication | 371631005 | DOID:594 |
Bipolar affective disorder, current episode depression | off-label use | 191627008 | DOID:3312 |
Seasonal affective disorder | off-label use | 247803002 | |
Cholestatic pruritus | off-label use | 707150004 | |
Suicidal thoughts | contraindication | 6471006 | |
Bipolar disorder | contraindication | 13746004 | DOID:3312 |
Neuroleptic malignant syndrome | contraindication | 15244003 | DOID:14464 |
Upper gastrointestinal hemorrhage | contraindication | 37372002 | |
Syndrome of inappropriate vasopressin secretion | contraindication | 55004003 | DOID:3401 |
Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
Weight loss | contraindication | 89362005 | |
Hyponatremia | contraindication | 89627008 | |
Seizure disorder | contraindication | 128613002 | |
Mania | contraindication | 231494001 | |
Hypomania | contraindication | 231496004 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Serotonin syndrome | contraindication | 371089000 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.61 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter | Transporter | INHIBITOR | Kd | 9.54 | CHEMBL | CHEMBL | |||
Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 7.24 | CHEMBL | |||||
Potassium voltage-gated channel subfamily H member 2 | Ion channel | Ki | 5.17 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Kd | 6.38 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 2A | GPCR | Ki | 6.11 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 5.67 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 6.25 | DRUG MATRIX | |||||
Alpha-1A adrenergic receptor | GPCR | Ki | 6.86 | WOMBAT-PK | |||||
Alpha-2B adrenergic receptor | GPCR | Ki | 7.08 | DRUG MATRIX | |||||
Muscarinic acetylcholine receptor M1 | GPCR | Ki | 6.13 | PDSP | |||||
Muscarinic acetylcholine receptor M2 | GPCR | Ki | 5.68 | PDSP | |||||
Muscarinic acetylcholine receptor M3 | GPCR | Ki | 5.89 | PDSP | |||||
Muscarinic acetylcholine receptor M4 | GPCR | Ki | 5.85 | PDSP | |||||
Muscarinic acetylcholine receptor M5 | GPCR | Ki | 5.72 | PDSP | |||||
Alpha-2C adrenergic receptor | GPCR | Ki | 6.19 | DRUG MATRIX | |||||
Sodium-dependent dopamine transporter | Transporter | Kd | 7.60 | WOMBAT-PK | |||||
Cytochrome P450 2C19 | Enzyme | IC50 | 6 | DRUG MATRIX | |||||
Melanocortin receptor 5 | GPCR | Ki | 5.37 | DRUG MATRIX | |||||
Alpha-2A adrenergic receptor | GPCR | Ki | 6.97 | DRUG MATRIX | |||||
Alpha-1B adrenergic receptor | GPCR | Ki | 6.48 | DRUG MATRIX | |||||
Membrane-associated progesterone receptor component 1 | Membrane receptor | Ki | 5.89 | DRUG MATRIX | |||||
Sodium-dependent serotonin transporter | Transporter | Ki | 9.07 | CHEMBL | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 7.11 | CHEMBL | |||||
Sigma non-opioid intracellular receptor 1 | Membrane receptor | Ki | 7.24 | CHEMBL | |||||
Transporter | Transporter | Ki | 6.80 | CHEMBL | |||||
Transcriptional activator protein luxR | Unclassified | IC50 | 4.57 | CHEMBL | |||||
Sigma intracellular receptor 2 | Unclassified | Ki | 5.28 | CHEMBL |
ID | Source |
---|---|
4020551 | VUID |
N0000148257 | NUI |
D00825 | KEGG_DRUG |
79559-97-0 | SECONDARY_CAS_RN |
4020394 | VANDF |
4020551 | VANDF |
C0074393 | UMLSCUI |
CHEBI:9123 | CHEBI |
SRE | PDB_CHEM_ID |
CHEMBL809 | ChEMBL_ID |
DB01104 | DRUGBANK_ID |
CHEMBL1709 | ChEMBL_ID |
D020280 | MESH_DESCRIPTOR_UI |
68617 | PUBCHEM_CID |
4798 | IUPHAR_LIGAND_ID |
5277 | INN_ID |
QUC7NX6WMB | UNII |
155137 | RXNORM |
169461 | MMSL |
39959 | MMSL |
5457 | MMSL |
83167 | MMSL |
d00880 | MMSL |
003629 | NDDF |
004615 | NDDF |
321958004 | SNOMEDCT_US |
372594008 | SNOMEDCT_US |
96211006 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Zoloft | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0049-0050 | SOLUTION, CONCENTRATE | 20 mg | ORAL | NDA | 32 sections |
Zoloft | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0049-4900 | TABLET, FILM COATED | 50 mg | ORAL | NDA | 32 sections |
Zoloft | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0049-4910 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 32 sections |
Zoloft | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0049-4960 | TABLET, FILM COATED | 25 mg | ORAL | NDA | 32 sections |
Sertraline Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9580 | TABLET, FILM COATED | 100 mg | ORAL | ANDA | 31 sections |
Sertraline Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9581 | TABLET, FILM COATED | 50 mg | ORAL | ANDA | 31 sections |
Sertraline Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9582 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 31 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9654 | TABLET, FILM COATED | 100 mg | ORAL | ANDA | 31 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9655 | TABLET, FILM COATED | 50 mg | ORAL | ANDA | 31 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9656 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 31 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7989 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 24 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7990 | TABLET, FILM COATED | 50 mg | ORAL | ANDA | 24 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7991 | TABLET, FILM COATED | 100 mg | ORAL | ANDA | 24 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6924 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 30 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6925 | TABLET, FILM COATED | 50 mg | ORAL | ANDA | 30 sections |
Sertraline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6926 | TABLET, FILM COATED | 100 mg | ORAL | ANDA | 30 sections |
Sertraline Hydrochloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10135-694 | SOLUTION | 20 mg | ORAL | ANDA | 28 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 13107-011 | TABLET | 25 mg | ORAL | ANDA | 26 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 13107-012 | TABLET | 50 mg | ORAL | ANDA | 26 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 13107-013 | TABLET | 100 mg | ORAL | ANDA | 26 sections |
ZOLOFT | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-250 | TABLET, FILM COATED | 50 mg | ORAL | NDA | 31 sections |
ZOLOFT | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-251 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 31 sections |
SERTRALINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-416 | TABLET | 100 mg | ORAL | ANDA | 25 sections |
SERTRALINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-457 | TABLET | 50 mg | ORAL | ANDA | 25 sections |
SERTRALINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-700 | TABLET | 25 mg | ORAL | ANDA | 25 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 16714-601 | SOLUTION | 20 mg | ORAL | ANDA | 30 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 16714-611 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 31 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 16714-612 | TABLET, FILM COATED | 50 mg | ORAL | ANDA | 31 sections |
Sertraline Hydrochloride | Human Prescription Drug Label | 1 | 16714-613 | TABLET, FILM COATED | 100 mg | ORAL | ANDA | 31 sections |
SERTRALINE HYDROCHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-215 | TABLET, FILM COATED | 25 mg | ORAL | ANDA | 29 sections |