piromidic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibacterials, nalidixic acid derivatives 2209 19562-30-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • piromidic acid
  • pyromidic acid
Antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.
  • Molecular weight: 288.31
  • Formula: C14H16N4O3
  • CLOGP: 0.99
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 1
  • TPSA: 86.63
  • ALOGS: -2.38
  • ROTB: 3

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01MB03 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Other quinolones
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary
CHEBI has role CHEBI:36047 antibacterial drugs
CHEBI has role CHEBI:59517 DNA synthesis inhibitors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 5.55 acidic
pKa2 6.43 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01431 KEGG_DRUG
C0031987 UMLSCUI
CHEBI:32019 CHEBI
CHEMBL311350 ChEMBL_ID
DB13744 DRUGBANK_ID
D010893 MESH_DESCRIPTOR_UI
4855 PUBCHEM_CID
12475 IUPHAR_LIGAND_ID
3198 INN_ID
3I12WH4EWF UNII

Pharmaceutical products:

None