DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
nemonoxacin 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antibacterials, nalidixic acid derivatives
5079
378746-64-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
nemonoxacin
taigexyn
TG 873870
TG-873870
has antibacterial activity
Molecular weight: 371.44
Formula: C20H25N3O4
CLOGP: -0.01
LIPINSKI: 0
HAC: 7
HDO: 2
TPSA: 96.10
ALOGS: -2.91
ROTB: 4
Drug dosage:
None
ADMET properties:
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Property
Value
Reference
CL (Clearance)
3.80 mL/min/kg
Lombardo F, Berellini G, Obach RS
t_half (Half-life)
13.50 hours
Lombardo F, Berellini G, Obach RS
Vd (Volume of distribution)
1.90 L/kg
Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma)
0.84 %
Lombardo F, Berellini G, Obach RS
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Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
J01MB08
ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
QUINOLONE ANTIBACTERIALS
Other quinolones
MeSH PA
D000900
Anti-Bacterial Agents
MeSH PA
D000890
Anti-Infective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Community acquired pneumonia
indication
385093006
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
6.37
acidic
pKa2
10.19
Basic
pKa3
5.04
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
10836
IUPHAR_LIGAND_ID
11993740
PUBCHEM_CID
8789
INN_ID
C2742587
UMLSCUI
C543520
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:136053
CHEBI
CHEMBL1213456
ChEMBL_ID
DB06600
DRUGBANK_ID
P94L0PVO94
UNII
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Pharmaceutical products:
None
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nemonoxacin