otilonium bromide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2003 | 26095-59-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
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Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Apraxia | 77.27 | 70.89 | 12 | 240 | 1809 | 63486961 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Apraxia | 69.01 | 53.24 | 12 | 385 | 2855 | 79741136 |
| Perseveration | 58.53 | 53.24 | 8 | 389 | 389 | 79743602 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03AB06 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, quaternary ammonium compounds |
| ATC | A03CA04 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS Synthetic anticholinergic agents in combination with psycholeptics |
| MeSH PA | D002121 | Calcium Channel Blockers |
| MeSH PA | D000077264 | Calcium-Regulating Hormones and Agents |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D018678 | Cholinergic Agents |
| MeSH PA | D018680 | Cholinergic Antagonists |
| MeSH PA | D005765 | Gastrointestinal Agents |
| MeSH PA | D049990 | Membrane Transport Modulators |
| MeSH PA | D018727 | Muscarinic Antagonists |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D010276 | Parasympatholytics |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.34 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07083 | KEGG_DRUG |
| 105360-89-2 | SECONDARY_CAS_RN |
| CHEBI:135780 | CHEBI |
| 7TB | PDB_CHEM_ID |
| CHEMBL2103773 | ChEMBL_ID |
| CHEMBL1433361 | ChEMBL_ID |
| C013934 | MESH_SUPPLEMENTAL_RECORD_UI |
| 4325 | INN_ID |
| 21HN3N72PV | UNII |
| DB13500 | DRUGBANK_ID |
| 32311 | RXNORM |
| 004187 | NDDF |
| 006121 | NDDF |
| 703514002 | SNOMEDCT_US |
| 703515001 | SNOMEDCT_US |
| 703516000 | SNOMEDCT_US |
| C0134250 | UMLSCUI |
| 72092 | PUBCHEM_CID |
Pharmaceutical products:
None