penthienate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
2093 22064-27-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • penthienate bromide
  • monodral
  • penthienate
  • Molecular weight: 340.50
  • Formula: C18H30NO3S
  • CLOGP: -0.04
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -5.37
  • ROTB: 9

Drug dosage:

DoseUnitRoute
15 mg O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIK3CG,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,ZAP70 42
kinase-selectivity-class AXL,BRAF,CDK4,GRK2,PDK4,STK33 6
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AB04 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthetic anticholinergics, quaternary ammonium compounds

Related Drugs by ATC class:

A03AB Synthetic anticholinergics, quaternary ammonium compounds 19 drugs
(2-benzhydryloxyethyl)diethyl-methylammonium iodidebenziloniumbevoniumdiphemanilfenpiveriniumglycopyrronium bromidehexocycliumisopropamidemepenzolatemethantheliniumotilonium bromideoxyphenonium show all 19 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Peptic ulcer indication 13200003 DOID:750
Gastric spasm indication 196754001




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07081 KEGG_DRUG
60-44-6 SECONDARY_CAS_RN
C0301375 UMLSCUI
CHEBI:135447 CHEBI
CHEMBL2110700 ChEMBL_ID
CHEMBL2105315 ChEMBL_ID
DB13695 DRUGBANK_ID
C102258 MESH_SUPPLEMENTAL_RECORD_UI
6067 PUBCHEM_CID
6LCT38OJV9 UNII
001741 NDDF
004697 NDDF
19524002 SNOMEDCT_US
22769006 SNOMEDCT_US

Pharmaceutical products:

None