Stem definition | Drug id | CAS RN |
---|---|---|
1860 | 37415-62-6 |
Dose | Unit | Route |
---|---|---|
2 | g | O |
2 | g | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 64.22 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 0.77 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 2.33 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.02 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 9.70 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 27, 2004 | FDA | NOVARTIS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Cytomegalovirus infection | 731.77 | 12.08 | 305 | 29551 | 17657 | 50557611 |
Transplant rejection | 518.96 | 12.08 | 200 | 29656 | 9409 | 50565859 |
Kidney transplant rejection | 426.58 | 12.08 | 138 | 29718 | 3849 | 50571419 |
Post transplant lymphoproliferative disorder | 344.33 | 12.08 | 119 | 29737 | 4085 | 50571183 |
Complications of transplanted kidney | 306.85 | 12.08 | 93 | 29763 | 2080 | 50573188 |
Polyomavirus-associated nephropathy | 234.56 | 12.08 | 70 | 29786 | 1482 | 50573786 |
Thrombotic microangiopathy | 222.22 | 12.08 | 107 | 29749 | 8684 | 50566584 |
Cytomegalovirus viraemia | 198.45 | 12.08 | 82 | 29774 | 4627 | 50570641 |
BK virus infection | 192.04 | 12.08 | 70 | 29786 | 2811 | 50572457 |
Product use in unapproved indication | 188.27 | 12.08 | 283 | 29573 | 115536 | 50459732 |
COVID-19 | 185.91 | 12.08 | 180 | 29676 | 46482 | 50528786 |
Epstein-Barr virus infection | 182.43 | 12.08 | 87 | 29769 | 6910 | 50568358 |
Posterior reversible encephalopathy syndrome | 176.72 | 12.08 | 110 | 29746 | 14818 | 50560450 |
Immunosuppressant drug level increased | 165.79 | 12.08 | 64 | 29792 | 3018 | 50572250 |
Off label use | 163.91 | 12.08 | 631 | 29225 | 473795 | 50101473 |
Delayed graft function | 158.31 | 12.08 | 46 | 29810 | 884 | 50574384 |
Leukopenia | 156.53 | 12.08 | 196 | 29660 | 67332 | 50507936 |
Kidney fibrosis | 141.89 | 12.08 | 48 | 29808 | 1541 | 50573727 |
Pneumocystis jirovecii pneumonia | 139.02 | 12.08 | 94 | 29762 | 14569 | 50560699 |
Chronic allograft nephropathy | 126.94 | 12.08 | 36 | 29820 | 632 | 50574636 |
Parvovirus B19 infection | 123.85 | 12.08 | 33 | 29823 | 454 | 50574814 |
Blood creatinine increased | 112.27 | 12.08 | 178 | 29678 | 75982 | 50499286 |
Renal impairment | 110.38 | 12.08 | 176 | 29680 | 75485 | 50499783 |
Nephropathy toxic | 107.42 | 12.08 | 64 | 29792 | 7965 | 50567303 |
Graft versus host disease in skin | 99.27 | 12.08 | 42 | 29814 | 2514 | 50572754 |
Trichodysplasia spinulosa | 95.15 | 12.08 | 27 | 29829 | 475 | 50574793 |
Graft versus host disease in gastrointestinal tract | 92.62 | 12.08 | 41 | 29815 | 2740 | 50572528 |
Histoplasmosis disseminated | 92.27 | 12.08 | 33 | 29823 | 1253 | 50574015 |
Multiple organ dysfunction syndrome | 91.81 | 12.08 | 130 | 29726 | 50207 | 50525061 |
Escherichia infection | 89.33 | 12.08 | 64 | 29792 | 10877 | 50564391 |
Tubulointerstitial nephritis | 89.06 | 12.08 | 73 | 29783 | 15138 | 50560130 |
West Nile viral infection | 88.46 | 12.08 | 24 | 29832 | 355 | 50574913 |
Cryptococcosis | 87.94 | 12.08 | 29 | 29827 | 859 | 50574409 |
Aspergillus infection | 87.70 | 12.08 | 53 | 29803 | 6768 | 50568500 |
Renal transplant failure | 85.53 | 12.08 | 26 | 29830 | 587 | 50574681 |
Varicella zoster virus infection | 83.88 | 12.08 | 37 | 29819 | 2452 | 50572816 |
Lymphocele | 83.01 | 12.08 | 27 | 29829 | 765 | 50574503 |
Human herpesvirus 6 infection | 82.25 | 12.08 | 37 | 29819 | 2569 | 50572699 |
Epstein-Barr viraemia | 80.34 | 12.08 | 27 | 29829 | 849 | 50574419 |
Acute kidney injury | 78.82 | 12.08 | 304 | 29552 | 227754 | 50347514 |
Transplant dysfunction | 77.81 | 12.08 | 43 | 29813 | 4641 | 50570627 |
Respiratory failure | 73.93 | 12.08 | 165 | 29691 | 91016 | 50484252 |
Arthropathy | 70.83 | 12.08 | 6 | 29850 | 157900 | 50417368 |
Fatigue | 70.35 | 12.08 | 201 | 29655 | 707400 | 49867868 |
Apoptosis | 69.38 | 12.08 | 15 | 29841 | 77 | 50575191 |
Pain | 67.09 | 12.08 | 152 | 29704 | 578751 | 49996517 |
Graft loss | 66.76 | 12.08 | 19 | 29837 | 338 | 50574930 |
Adenovirus infection | 66.52 | 12.08 | 34 | 29822 | 3134 | 50572134 |
Liver transplant rejection | 66.19 | 12.08 | 26 | 29830 | 1284 | 50573984 |
Polyomavirus viraemia | 61.76 | 12.08 | 19 | 29837 | 447 | 50574821 |
Histoplasmosis | 58.80 | 12.08 | 26 | 29830 | 1733 | 50573535 |
Post transplant distal limb syndrome | 58.41 | 12.08 | 15 | 29841 | 177 | 50575091 |
Aplasia pure red cell | 57.43 | 12.08 | 34 | 29822 | 4181 | 50571087 |
Cytomegalovirus colitis | 56.52 | 12.08 | 26 | 29830 | 1901 | 50573367 |
Diffuse large B-cell lymphoma | 55.34 | 12.08 | 37 | 29819 | 5625 | 50569643 |
Focal segmental glomerulosclerosis | 55.30 | 12.08 | 23 | 29833 | 1318 | 50573950 |
JC virus infection | 54.84 | 12.08 | 25 | 29831 | 1790 | 50573478 |
Bronchopulmonary aspergillosis | 54.28 | 12.08 | 41 | 29815 | 7551 | 50567717 |
Klebsiella infection | 54.00 | 12.08 | 40 | 29816 | 7154 | 50568114 |
Renal tubular atrophy | 53.68 | 12.08 | 18 | 29838 | 562 | 50574706 |
Drug hypersensitivity | 53.35 | 12.08 | 42 | 29814 | 250968 | 50324300 |
Disseminated cryptococcosis | 52.10 | 12.08 | 16 | 29840 | 374 | 50574894 |
Human polyomavirus infection | 52.08 | 12.08 | 15 | 29841 | 279 | 50574989 |
Ureaplasma infection | 51.63 | 12.08 | 17 | 29839 | 501 | 50574767 |
Human ehrlichiosis | 50.50 | 12.08 | 13 | 29843 | 155 | 50575113 |
Blastomycosis | 49.95 | 12.08 | 14 | 29842 | 235 | 50575033 |
Haemophagocytic lymphohistiocytosis | 49.63 | 12.08 | 41 | 29815 | 8592 | 50566676 |
Rash | 48.87 | 12.08 | 117 | 29739 | 437354 | 50137914 |
Pancreas transplant rejection | 48.00 | 12.08 | 12 | 29844 | 126 | 50575142 |
Drug level increased | 47.93 | 12.08 | 58 | 29798 | 19210 | 50556058 |
Arthralgia | 46.91 | 12.08 | 120 | 29736 | 438582 | 50136686 |
Graft versus host disease | 45.64 | 12.08 | 34 | 29822 | 6132 | 50569136 |
Fall | 45.50 | 12.08 | 80 | 29776 | 334852 | 50240416 |
Central nervous system lymphoma | 45.06 | 12.08 | 20 | 29836 | 1345 | 50573923 |
Contraindicated product administered | 44.71 | 12.08 | 16 | 29840 | 148942 | 50426326 |
Diabetes mellitus | 43.44 | 12.08 | 92 | 29764 | 48941 | 50526327 |
Viraemia | 42.86 | 12.08 | 18 | 29838 | 1057 | 50574211 |
Angiosarcoma | 42.19 | 12.08 | 12 | 29844 | 213 | 50575055 |
Renal tubular necrosis | 41.91 | 12.08 | 40 | 29816 | 10128 | 50565140 |
Phaeohyphomycosis | 41.57 | 12.08 | 12 | 29844 | 225 | 50575043 |
Injection site pain | 40.74 | 12.08 | 8 | 29848 | 111016 | 50464252 |
Renal transplant | 40.68 | 12.08 | 18 | 29838 | 1201 | 50574067 |
Proteinuria | 39.72 | 12.08 | 49 | 29807 | 16548 | 50558720 |
Immunosuppressant drug level decreased | 39.46 | 12.08 | 16 | 29840 | 859 | 50574409 |
Encephalitis viral | 39.02 | 12.08 | 19 | 29837 | 1578 | 50573690 |
Joint swelling | 38.62 | 12.08 | 53 | 29803 | 245233 | 50330035 |
Toxoplasmosis | 38.09 | 12.08 | 18 | 29838 | 1399 | 50573869 |
Nocardiosis | 37.92 | 12.08 | 19 | 29837 | 1679 | 50573589 |
Haemolytic uraemic syndrome | 37.73 | 12.08 | 21 | 29835 | 2298 | 50572970 |
Disseminated mucormycosis | 37.30 | 12.08 | 10 | 29846 | 141 | 50575127 |
Biopsy lung abnormal | 37.23 | 12.08 | 10 | 29846 | 142 | 50575126 |
Hypersensitivity | 36.44 | 12.08 | 44 | 29812 | 215117 | 50360151 |
Diarrhoea | 36.13 | 12.08 | 516 | 29340 | 587960 | 49987308 |
Atypical haemolytic uraemic syndrome | 35.14 | 12.08 | 13 | 29843 | 544 | 50574724 |
Renal failure | 35.00 | 12.08 | 140 | 29716 | 106493 | 50468775 |
Acute graft versus host disease | 34.26 | 12.08 | 24 | 29832 | 3934 | 50571334 |
Interstitial lung disease | 34.19 | 12.08 | 88 | 29768 | 53088 | 50522180 |
Enterococcal infection | 34.01 | 12.08 | 30 | 29826 | 6868 | 50568400 |
Alveolar proteinosis | 33.91 | 12.08 | 11 | 29845 | 309 | 50574959 |
Synovitis | 32.83 | 12.08 | 16 | 29840 | 123849 | 50451419 |
Infusion related reaction | 32.80 | 12.08 | 31 | 29825 | 169526 | 50405742 |
Wound | 32.37 | 12.08 | 11 | 29845 | 105783 | 50469485 |
Acute respiratory distress syndrome | 32.00 | 12.08 | 50 | 29806 | 21049 | 50554219 |
Gastroenteritis norovirus | 31.69 | 12.08 | 17 | 29839 | 1730 | 50573538 |
Pyrexia | 31.65 | 12.08 | 353 | 29503 | 379850 | 50195418 |
Rhodococcus infection | 31.42 | 12.08 | 8 | 29848 | 91 | 50575177 |
Dizziness | 30.96 | 12.08 | 103 | 29753 | 346266 | 50229002 |
Hypogammaglobulinaemia | 30.55 | 12.08 | 26 | 29830 | 5673 | 50569595 |
Escherichia urinary tract infection | 30.38 | 12.08 | 34 | 29822 | 10361 | 50564907 |
Pruritus | 29.91 | 12.08 | 78 | 29778 | 283490 | 50291778 |
Protein urine present | 29.79 | 12.08 | 25 | 29831 | 5352 | 50569916 |
Rheumatoid arthritis | 29.68 | 12.08 | 46 | 29810 | 202504 | 50372764 |
Malacoplakia vesicae | 29.60 | 12.08 | 7 | 29849 | 57 | 50575211 |
Pseudomonas infection | 29.56 | 12.08 | 32 | 29824 | 9398 | 50565870 |
Biloma | 29.28 | 12.08 | 7 | 29849 | 60 | 50575208 |
Malacoplakia gastrointestinal | 29.07 | 12.08 | 7 | 29849 | 62 | 50575206 |
Swelling | 29.07 | 12.08 | 46 | 29810 | 200826 | 50374442 |
Hospitalisation | 28.86 | 12.08 | 97 | 29759 | 67840 | 50507428 |
Cystitis haemorrhagic | 28.72 | 12.08 | 21 | 29835 | 3681 | 50571587 |
Discomfort | 28.72 | 12.08 | 14 | 29842 | 108366 | 50466902 |
Urinary tract infection | 28.65 | 12.08 | 228 | 29628 | 223792 | 50351476 |
Stomatitis | 28.56 | 12.08 | 12 | 29844 | 101332 | 50473936 |
Brain abscess | 28.54 | 12.08 | 16 | 29840 | 1775 | 50573493 |
Vaccination failure | 28.41 | 12.08 | 10 | 29846 | 362 | 50574906 |
Microsporidia infection | 28.37 | 12.08 | 9 | 29847 | 235 | 50575033 |
Injection site erythema | 28.34 | 12.08 | 5 | 29851 | 74931 | 50500337 |
Mycobacterium avium complex infection | 28.31 | 12.08 | 18 | 29838 | 2512 | 50572756 |
Haemolytic anaemia | 28.20 | 12.08 | 31 | 29825 | 9261 | 50566007 |
Renal tubular injury | 27.83 | 12.08 | 10 | 29846 | 385 | 50574883 |
Progressive multifocal leukoencephalopathy | 27.70 | 12.08 | 34 | 29822 | 11423 | 50563845 |
Human herpesvirus 6 encephalitis | 27.66 | 12.08 | 8 | 29848 | 151 | 50575117 |
Disseminated mycobacterium avium complex infection | 27.25 | 12.08 | 6 | 29850 | 34 | 50575234 |
Philadelphia positive chronic myeloid leukaemia | 27.11 | 12.08 | 6 | 29850 | 35 | 50575233 |
Acute graft versus host disease in intestine | 27.10 | 12.08 | 15 | 29841 | 1624 | 50573644 |
Malignant neoplasm progression | 26.98 | 12.08 | 4 | 29852 | 68120 | 50507148 |
Lupus nephritis | 26.97 | 12.08 | 17 | 29839 | 2338 | 50572930 |
End stage renal disease | 26.40 | 12.08 | 24 | 29832 | 5713 | 50569555 |
Insomnia | 26.30 | 12.08 | 39 | 29817 | 174826 | 50400442 |
Pyelonephritis | 26.26 | 12.08 | 38 | 29818 | 14951 | 50560317 |
Cytomegalovirus hepatitis | 26.05 | 12.08 | 9 | 29847 | 308 | 50574960 |
Bacterial pyelonephritis | 25.75 | 12.08 | 9 | 29847 | 319 | 50574949 |
Pemphigus | 25.63 | 12.08 | 20 | 29836 | 120146 | 50455122 |
Graft complication | 25.47 | 12.08 | 8 | 29848 | 202 | 50575066 |
Anxiety | 25.38 | 12.08 | 41 | 29815 | 177565 | 50397703 |
Obliterative bronchiolitis | 25.38 | 12.08 | 15 | 29841 | 1838 | 50573430 |
Hepatitis E | 25.25 | 12.08 | 13 | 29843 | 1216 | 50574052 |
Lymphopenia | 25.06 | 12.08 | 38 | 29818 | 15583 | 50559685 |
Disseminated varicella zoster vaccine virus infection | 25.04 | 12.08 | 6 | 29850 | 52 | 50575216 |
Chromoblastomycosis | 25.01 | 12.08 | 5 | 29851 | 16 | 50575252 |
Infection reactivation | 24.89 | 12.08 | 12 | 29844 | 975 | 50574293 |
Contusion | 24.79 | 12.08 | 18 | 29838 | 112165 | 50463103 |
Cytomegalovirus nephritis | 24.78 | 12.08 | 5 | 29851 | 17 | 50575251 |
Depression | 24.77 | 12.08 | 37 | 29819 | 165386 | 50409882 |
Herpes simplex oesophagitis | 24.67 | 12.08 | 7 | 29849 | 123 | 50575145 |
Incision site pain | 24.62 | 12.08 | 12 | 29844 | 999 | 50574269 |
Diabetic macroangiopathy | 24.57 | 12.08 | 7 | 29849 | 125 | 50575143 |
Hyperammonaemia | 24.20 | 12.08 | 21 | 29835 | 4703 | 50570565 |
Intentional overdose | 24.01 | 12.08 | 4 | 29852 | 62500 | 50512768 |
Escherichia pyelonephritis | 24.01 | 12.08 | 9 | 29847 | 391 | 50574877 |
Urinary fistula | 23.95 | 12.08 | 5 | 29851 | 21 | 50575247 |
Alopecia | 23.90 | 12.08 | 70 | 29786 | 244977 | 50330291 |
Anogenital warts | 23.83 | 12.08 | 9 | 29847 | 399 | 50574869 |
Septic shock | 23.73 | 12.08 | 81 | 29775 | 57094 | 50518174 |
Nasopharyngitis | 23.60 | 12.08 | 49 | 29807 | 192878 | 50382390 |
Agranulocytosis | 23.54 | 12.08 | 44 | 29812 | 21377 | 50553891 |
Coccidioidomycosis | 23.33 | 12.08 | 11 | 29845 | 851 | 50574417 |
Psoriasis | 23.24 | 12.08 | 6 | 29850 | 68994 | 50506274 |
Liver abscess | 23.09 | 12.08 | 16 | 29840 | 2577 | 50572691 |
Osteoarthritis | 23.04 | 12.08 | 6 | 29850 | 68600 | 50506668 |
Heart transplant rejection | 22.90 | 12.08 | 9 | 29847 | 445 | 50574823 |
Perinephric abscess | 22.78 | 12.08 | 7 | 29849 | 164 | 50575104 |
Cytomegalovirus chorioretinitis | 22.76 | 12.08 | 13 | 29843 | 1494 | 50573774 |
Drug interaction | 22.74 | 12.08 | 198 | 29658 | 199423 | 50375845 |
Cat scratch disease | 22.74 | 12.08 | 7 | 29849 | 165 | 50575103 |
Blister | 22.68 | 12.08 | 11 | 29845 | 85407 | 50489861 |
Pancytopenia | 22.68 | 12.08 | 104 | 29752 | 83926 | 50491342 |
Pyelonephritis acute | 22.65 | 12.08 | 19 | 29837 | 4064 | 50571204 |
Enterobacter infection | 22.55 | 12.08 | 14 | 29842 | 1874 | 50573394 |
Polyomavirus test positive | 22.55 | 12.08 | 6 | 29850 | 82 | 50575186 |
Suicidal ideation | 22.53 | 12.08 | 3 | 29853 | 55382 | 50519886 |
Central nervous system lupus | 22.39 | 12.08 | 8 | 29848 | 303 | 50574965 |
Cerebral toxoplasmosis | 22.30 | 12.08 | 10 | 29846 | 689 | 50574579 |
Cytomegalovirus syndrome | 22.22 | 12.08 | 6 | 29850 | 87 | 50575181 |
Balance disorder | 22.18 | 12.08 | 7 | 29849 | 70583 | 50504685 |
Necrotising herpetic retinopathy | 22.16 | 12.08 | 6 | 29850 | 88 | 50575180 |
Disseminated cytomegaloviral infection | 22.13 | 12.08 | 7 | 29849 | 181 | 50575087 |
Mycobacterial infection | 22.07 | 12.08 | 13 | 29843 | 1583 | 50573685 |
Systemic candida | 22.04 | 12.08 | 16 | 29840 | 2774 | 50572494 |
Abdominal discomfort | 21.99 | 12.08 | 67 | 29789 | 231574 | 50343694 |
Lung transplant | 21.86 | 12.08 | 16 | 29840 | 2809 | 50572459 |
Urinary tract candidiasis | 21.85 | 12.08 | 9 | 29847 | 503 | 50574765 |
Herpes simplex hepatitis | 21.85 | 12.08 | 8 | 29848 | 325 | 50574943 |
Papilloma viral infection | 21.71 | 12.08 | 12 | 29844 | 1295 | 50573973 |
Hydronephrosis | 21.71 | 12.08 | 26 | 29830 | 8515 | 50566753 |
Urinoma | 21.68 | 12.08 | 5 | 29851 | 36 | 50575232 |
Sepsis | 21.40 | 12.08 | 143 | 29713 | 132782 | 50442486 |
Lung transplant rejection | 21.38 | 12.08 | 10 | 29846 | 759 | 50574509 |
Mucormycosis | 21.36 | 12.08 | 15 | 29841 | 2468 | 50572800 |
Neutropenia | 21.36 | 12.08 | 155 | 29701 | 147810 | 50427458 |
Oesophageal candidiasis | 21.25 | 12.08 | 20 | 29836 | 4974 | 50570294 |
Pneumopericardium | 21.22 | 12.08 | 5 | 29851 | 40 | 50575228 |
Pyelonephritis fungal | 21.07 | 12.08 | 6 | 29850 | 107 | 50575161 |
Complications of transplanted lung | 20.89 | 12.08 | 7 | 29849 | 218 | 50575050 |
Rhinovirus infection | 20.76 | 12.08 | 17 | 29839 | 3517 | 50571751 |
Human herpesvirus 8 infection | 20.71 | 12.08 | 7 | 29849 | 224 | 50575044 |
Transplant failure | 20.68 | 12.08 | 12 | 29844 | 1421 | 50573847 |
Candida infection | 20.66 | 12.08 | 44 | 29812 | 23479 | 50551789 |
Pain in extremity | 20.54 | 12.08 | 87 | 29769 | 272778 | 50302490 |
Acid base balance abnormal | 20.25 | 12.08 | 7 | 29849 | 240 | 50575028 |
Dermatitis papillaris capillitii | 20.21 | 12.08 | 4 | 29852 | 12 | 50575256 |
Systemic bacterial infection | 20.21 | 12.08 | 4 | 29852 | 12 | 50575256 |
Drug level decreased | 20.18 | 12.08 | 22 | 29834 | 6511 | 50568757 |
Ureteral necrosis | 20.13 | 12.08 | 5 | 29851 | 51 | 50575217 |
Donor specific antibody present | 20.10 | 12.08 | 6 | 29850 | 127 | 50575141 |
Nosocomial infection | 20.01 | 12.08 | 12 | 29844 | 1510 | 50573758 |
Chronic kidney disease | 19.82 | 12.08 | 60 | 29796 | 39711 | 50535557 |
Therapeutic product effect decreased | 19.82 | 12.08 | 31 | 29825 | 136019 | 50439249 |
Mucinous adenocarcinoma of appendix | 19.74 | 12.08 | 4 | 29852 | 14 | 50575254 |
Pneumonia cytomegaloviral | 19.73 | 12.08 | 13 | 29843 | 1928 | 50573340 |
Encephalitis | 19.64 | 12.08 | 23 | 29833 | 7357 | 50567911 |
Pericarditis | 19.61 | 12.08 | 11 | 29845 | 78678 | 50496590 |
Plasmapheresis | 19.59 | 12.08 | 7 | 29849 | 265 | 50575003 |
Mycobacterium chelonae infection | 19.56 | 12.08 | 8 | 29848 | 439 | 50574829 |
Helicobacter infection | 19.50 | 12.08 | 3 | 29853 | 49699 | 50525569 |
Forced vital capacity decreased | 19.47 | 12.08 | 10 | 29846 | 931 | 50574337 |
Back pain | 19.24 | 12.08 | 66 | 29790 | 219964 | 50355304 |
Concomitant disease progression | 19.11 | 12.08 | 13 | 29843 | 2032 | 50573236 |
Renal lymphocele | 19.02 | 12.08 | 5 | 29851 | 65 | 50575203 |
American trypanosomiasis | 18.95 | 12.08 | 5 | 29851 | 66 | 50575202 |
Epstein-Barr virus associated lymphoproliferative disorder | 18.86 | 12.08 | 12 | 29844 | 1677 | 50573591 |
Pulmonary alveolar haemorrhage | 18.83 | 12.08 | 17 | 29839 | 4010 | 50571258 |
Bacillary angiomatosis | 18.55 | 12.08 | 5 | 29851 | 72 | 50575196 |
Hypoaesthesia | 18.53 | 12.08 | 29 | 29827 | 127228 | 50448040 |
Emphysematous pyelonephritis | 18.38 | 12.08 | 6 | 29850 | 172 | 50575096 |
Smooth muscle cell neoplasm | 18.32 | 12.08 | 9 | 29847 | 762 | 50574506 |
Irritable bowel syndrome | 18.26 | 12.08 | 4 | 29852 | 51437 | 50523831 |
Constipation | 18.13 | 12.08 | 53 | 29803 | 185655 | 50389613 |
Encephalitis cytomegalovirus | 18.08 | 12.08 | 8 | 29848 | 534 | 50574734 |
Wheezing | 18.04 | 12.08 | 7 | 29849 | 62040 | 50513228 |
Tuberculosis gastrointestinal | 17.99 | 12.08 | 7 | 29849 | 337 | 50574931 |
Neutrophil count increased | 17.96 | 12.08 | 31 | 29825 | 14164 | 50561104 |
Hypertriglyceridaemia | 17.86 | 12.08 | 19 | 29837 | 5472 | 50569796 |
Bacteroides bacteraemia | 17.84 | 12.08 | 4 | 29852 | 25 | 50575243 |
Glomerulosclerosis | 17.79 | 12.08 | 7 | 29849 | 347 | 50574921 |
Hyperamylasaemia | 17.76 | 12.08 | 7 | 29849 | 349 | 50574919 |
Acute motor axonal neuropathy | 17.70 | 12.08 | 4 | 29852 | 26 | 50575242 |
Fanconi syndrome | 17.70 | 12.08 | 10 | 29846 | 1126 | 50574142 |
Red blood cells urine positive | 17.69 | 12.08 | 14 | 29842 | 2761 | 50572507 |
Meningitis cryptococcal | 17.63 | 12.08 | 10 | 29846 | 1135 | 50574133 |
Bacteraemia | 17.58 | 12.08 | 31 | 29825 | 14402 | 50560866 |
Confusional state | 17.48 | 12.08 | 54 | 29802 | 185874 | 50389394 |
New onset diabetes after transplantation | 17.41 | 12.08 | 5 | 29851 | 92 | 50575176 |
Strongyloidiasis | 17.40 | 12.08 | 9 | 29847 | 850 | 50574418 |
Urosepsis | 17.29 | 12.08 | 32 | 29824 | 15433 | 50559835 |
COVID-19 pneumonia | 17.28 | 12.08 | 23 | 29833 | 8372 | 50566896 |
Oesophageal ulcer | 17.18 | 12.08 | 16 | 29840 | 3929 | 50571339 |
Sinusitis | 17.14 | 12.08 | 48 | 29808 | 170510 | 50404758 |
Brain natriuretic peptide increased | 17.14 | 12.08 | 17 | 29839 | 4510 | 50570758 |
Fibromyalgia | 17.01 | 12.08 | 3 | 29853 | 44975 | 50530293 |
Disease recurrence | 16.99 | 12.08 | 37 | 29819 | 20044 | 50555224 |
Gastrointestinal mucormycosis | 16.85 | 12.08 | 6 | 29850 | 225 | 50575043 |
Nephropathy | 16.76 | 12.08 | 18 | 29838 | 5240 | 50570028 |
Hepatic enzyme increased | 16.70 | 12.08 | 35 | 29821 | 137345 | 50437923 |
Malacoplakia | 16.61 | 12.08 | 5 | 29851 | 109 | 50575159 |
Disseminated tuberculosis | 16.56 | 12.08 | 13 | 29843 | 2533 | 50572735 |
Acanthamoeba infection | 16.56 | 12.08 | 4 | 29852 | 36 | 50575232 |
Scedosporium infection | 16.45 | 12.08 | 7 | 29849 | 425 | 50574843 |
Joint tuberculosis | 16.40 | 12.08 | 5 | 29851 | 114 | 50575154 |
Nephrotic syndrome | 16.39 | 12.08 | 17 | 29839 | 4753 | 50570515 |
Purulent pericarditis | 16.36 | 12.08 | 4 | 29852 | 38 | 50575230 |
Skin hypertrophy | 16.35 | 12.08 | 14 | 29842 | 3081 | 50572187 |
Biopsy kidney | 16.20 | 12.08 | 5 | 29851 | 119 | 50575149 |
Cardiac murmur functional | 16.18 | 12.08 | 4 | 29852 | 40 | 50575228 |
Pneumonia | 16.15 | 12.08 | 313 | 29543 | 378088 | 50197180 |
Neuropathy peripheral | 16.13 | 12.08 | 20 | 29836 | 96737 | 50478531 |
Drug resistance | 16.08 | 12.08 | 35 | 29821 | 18954 | 50556314 |
Pancreatitis necrotising | 16.08 | 12.08 | 10 | 29846 | 1343 | 50573925 |
Orbital apex syndrome | 16 | 12.08 | 4 | 29852 | 42 | 50575226 |
Epstein-Barr virus associated lymphoma | 15.89 | 12.08 | 7 | 29849 | 462 | 50574806 |
Influenza like illness | 15.87 | 12.08 | 7 | 29849 | 57452 | 50517816 |
Acute pulmonary histoplasmosis | 15.56 | 12.08 | 5 | 29851 | 136 | 50575132 |
Graft versus host disease in liver | 15.54 | 12.08 | 7 | 29849 | 487 | 50574781 |
Colitis | 15.47 | 12.08 | 54 | 29802 | 38475 | 50536793 |
Cytomegalovirus gastrointestinal infection | 15.44 | 12.08 | 6 | 29850 | 288 | 50574980 |
Necrotising retinitis | 15.26 | 12.08 | 6 | 29850 | 297 | 50574971 |
Meningitis histoplasma | 15.16 | 12.08 | 3 | 29853 | 9 | 50575259 |
Renal disorder | 15.14 | 12.08 | 43 | 29813 | 27462 | 50547806 |
Mycobacterium abscessus infection | 15.06 | 12.08 | 7 | 29849 | 524 | 50574744 |
Mobility decreased | 15 | 12.08 | 15 | 29841 | 79933 | 50495335 |
Urticaria | 14.92 | 12.08 | 34 | 29822 | 129527 | 50445741 |
Renal necrosis | 14.82 | 12.08 | 4 | 29852 | 58 | 50575210 |
B-cell lymphoma | 14.75 | 12.08 | 13 | 29843 | 2972 | 50572296 |
Therapy cessation | 14.65 | 12.08 | 41 | 29815 | 25970 | 50549298 |
Cardiac failure congestive | 14.54 | 12.08 | 17 | 29839 | 84365 | 50490903 |
Graft versus host disease in eye | 14.45 | 12.08 | 4 | 29852 | 64 | 50575204 |
Mucocutaneous leishmaniasis | 14.41 | 12.08 | 6 | 29850 | 345 | 50574923 |
Hepatic echinococciasis | 14.29 | 12.08 | 3 | 29853 | 13 | 50575255 |
Graft versus host disease in lung | 14.29 | 12.08 | 6 | 29850 | 352 | 50574916 |
Bacterial colitis | 14.17 | 12.08 | 4 | 29852 | 69 | 50575199 |
Lung diffusion test decreased | 14.15 | 12.08 | 7 | 29849 | 602 | 50574666 |
Pneumonia fungal | 14.14 | 12.08 | 15 | 29841 | 4305 | 50570963 |
Cytomegalovirus infection reactivation | 14.10 | 12.08 | 12 | 29844 | 2619 | 50572649 |
Anorexia nervosa | 14.05 | 12.08 | 5 | 29851 | 187 | 50575081 |
Leiomyosarcoma | 14 | 12.08 | 5 | 29851 | 189 | 50575079 |
Pathogen resistance | 13.94 | 12.08 | 17 | 29839 | 5672 | 50569596 |
Herpes simplex | 13.79 | 12.08 | 19 | 29837 | 7143 | 50568125 |
Normocytic anaemia | 13.76 | 12.08 | 9 | 29847 | 1318 | 50573950 |
Bronchiectasis | 13.72 | 12.08 | 23 | 29833 | 10260 | 50565008 |
Transplant | 13.72 | 12.08 | 7 | 29849 | 643 | 50574625 |
Anaemia | 13.69 | 12.08 | 217 | 29639 | 252239 | 50323029 |
Gastroenteritis cryptosporidial | 13.66 | 12.08 | 4 | 29852 | 79 | 50575189 |
Mycoplasma infection | 13.62 | 12.08 | 6 | 29850 | 396 | 50574872 |
Product monitoring error | 13.58 | 12.08 | 12 | 29844 | 2752 | 50572516 |
Anuria | 13.50 | 12.08 | 24 | 29832 | 11220 | 50564048 |
Histoplasmosis cutaneous | 13.34 | 12.08 | 3 | 29853 | 19 | 50575249 |
Pulmonary function test decreased | 13.34 | 12.08 | 13 | 29843 | 3375 | 50571893 |
Immunosuppression | 13.26 | 12.08 | 19 | 29837 | 7407 | 50567861 |
Pulmonary mucormycosis | 13.26 | 12.08 | 5 | 29851 | 221 | 50575047 |
Oesophageal stenosis | 13.24 | 12.08 | 12 | 29844 | 2846 | 50572422 |
Myocardial infarction | 13.23 | 12.08 | 20 | 29836 | 89007 | 50486261 |
Aphthous ulcer | 13.22 | 12.08 | 23 | 29833 | 10574 | 50564694 |
Nephrostomy | 13.21 | 12.08 | 4 | 29852 | 89 | 50575179 |
Chronic graft versus host disease | 13.21 | 12.08 | 12 | 29844 | 2855 | 50572413 |
Lymphoproliferative disorder | 13.17 | 12.08 | 12 | 29844 | 2865 | 50572403 |
Hyperuricaemia | 13.15 | 12.08 | 15 | 29841 | 4665 | 50570603 |
Intentional product use issue | 13.13 | 12.08 | 84 | 29772 | 76834 | 50498434 |
Gait disturbance | 13.10 | 12.08 | 45 | 29811 | 149960 | 50425308 |
Extremity necrosis | 12.92 | 12.08 | 9 | 29847 | 1462 | 50573806 |
Organising pneumonia | 12.91 | 12.08 | 15 | 29841 | 4759 | 50570509 |
Urinary tract infection bacterial | 12.84 | 12.08 | 14 | 29842 | 4145 | 50571123 |
Injection site bruising | 12.76 | 12.08 | 3 | 29853 | 36765 | 50538503 |
Bone marrow granuloma | 12.73 | 12.08 | 3 | 29853 | 24 | 50575244 |
Sterile pyuria | 12.73 | 12.08 | 3 | 29853 | 24 | 50575244 |
Neuroendocrine carcinoma of the skin | 12.70 | 12.08 | 6 | 29850 | 466 | 50574802 |
Squamous cell carcinoma | 12.66 | 12.08 | 19 | 29837 | 7720 | 50567548 |
Hepatic cyst infection | 12.66 | 12.08 | 4 | 29852 | 103 | 50575165 |
Bacterial sepsis | 12.64 | 12.08 | 13 | 29843 | 3599 | 50571669 |
Asthenia | 12.54 | 12.08 | 124 | 29732 | 318918 | 50256350 |
Fungaemia | 12.50 | 12.08 | 10 | 29846 | 2002 | 50573266 |
Weight increased | 12.48 | 12.08 | 69 | 29787 | 201822 | 50373446 |
Eye infection viral | 12.48 | 12.08 | 4 | 29852 | 108 | 50575160 |
Fungal sepsis | 12.39 | 12.08 | 8 | 29848 | 1146 | 50574122 |
Cystitis viral | 12.38 | 12.08 | 4 | 29852 | 111 | 50575157 |
Dry skin | 12.35 | 12.08 | 5 | 29851 | 43186 | 50532082 |
Poikilocytosis | 12.31 | 12.08 | 4 | 29852 | 113 | 50575155 |
Renal haemorrhage | 12.26 | 12.08 | 7 | 29849 | 804 | 50574464 |
Genital herpes | 12.20 | 12.08 | 9 | 29847 | 1598 | 50573670 |
Superinfection bacterial | 12.20 | 12.08 | 6 | 29850 | 509 | 50574759 |
Necrotising fasciitis | 12.19 | 12.08 | 11 | 29845 | 2593 | 50572675 |
Wrong technique in product usage process | 12.13 | 12.08 | 9 | 29847 | 55501 | 50519767 |
Pneumonia haemophilus | 12.08 | 12.08 | 6 | 29850 | 520 | 50574748 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Kidney transplant rejection | 673.95 | 12.56 | 271 | 35989 | 6734 | 29531533 |
Cytomegalovirus infection | 575.86 | 12.56 | 357 | 35903 | 22858 | 29515409 |
Transplant rejection | 511.67 | 12.56 | 242 | 36018 | 8970 | 29529297 |
Complications of transplanted kidney | 429.30 | 12.56 | 167 | 36093 | 3787 | 29534480 |
COVID-19 | 395.29 | 12.56 | 338 | 35922 | 35676 | 29502591 |
Polyomavirus-associated nephropathy | 308.01 | 12.56 | 126 | 36134 | 3270 | 29534997 |
Post transplant lymphoproliferative disorder | 252.92 | 12.56 | 127 | 36133 | 5366 | 29532901 |
Immunosuppressant drug level increased | 251.74 | 12.56 | 121 | 36139 | 4644 | 29533623 |
BK virus infection | 250.11 | 12.56 | 120 | 36140 | 4587 | 29533680 |
Transplant dysfunction | 222.28 | 12.56 | 89 | 36171 | 2181 | 29536086 |
Hepatitis E | 207.87 | 12.56 | 78 | 36182 | 1596 | 29536671 |
Renal transplant failure | 199.46 | 12.56 | 66 | 36194 | 917 | 29537350 |
Thrombotic microangiopathy | 193.75 | 12.56 | 125 | 36135 | 8556 | 29529711 |
Blood creatinine increased | 191.09 | 12.56 | 360 | 35900 | 84742 | 29453525 |
Cytomegalovirus viraemia | 163.63 | 12.56 | 100 | 36160 | 6220 | 29532047 |
Leukopenia | 158.12 | 12.56 | 260 | 36000 | 54943 | 29483324 |
West Nile viral infection | 149.54 | 12.56 | 48 | 36212 | 602 | 29537665 |
Delayed graft function | 146.27 | 12.56 | 63 | 36197 | 1864 | 29536403 |
JC virus infection | 140.65 | 12.56 | 61 | 36199 | 1836 | 29536431 |
Aspergillus infection | 140.39 | 12.56 | 111 | 36149 | 10470 | 29527797 |
Product use in unapproved indication | 138.06 | 12.56 | 319 | 35941 | 86556 | 29451711 |
Parvovirus B19 infection | 136.52 | 12.56 | 46 | 36214 | 678 | 29537589 |
Transplant failure | 122.62 | 12.56 | 63 | 36197 | 2793 | 29535474 |
Nephropathy toxic | 122.01 | 12.56 | 103 | 36157 | 10653 | 29527614 |
Incision site pain | 115.02 | 12.56 | 52 | 36208 | 1731 | 29536536 |
Epstein-Barr virus infection | 108.86 | 12.56 | 79 | 36181 | 6550 | 29531717 |
Cryptococcosis | 107.44 | 12.56 | 51 | 36209 | 1901 | 29536366 |
Mucormycosis | 107.08 | 12.56 | 71 | 36189 | 5087 | 29533180 |
Drug level increased | 106.22 | 12.56 | 123 | 36137 | 18664 | 29519603 |
Renal tubular atrophy | 102.55 | 12.56 | 41 | 36219 | 1000 | 29537267 |
Nocardiosis | 101.18 | 12.56 | 58 | 36202 | 3202 | 29535065 |
Kidney fibrosis | 99.15 | 12.56 | 49 | 36211 | 1998 | 29536269 |
Bronchopulmonary aspergillosis | 96.57 | 12.56 | 96 | 36164 | 12248 | 29526019 |
Phaeohyphomycosis | 94.70 | 12.56 | 36 | 36224 | 764 | 29537503 |
Pseudomonas infection | 91.63 | 12.56 | 88 | 36172 | 10764 | 29527503 |
COVID-19 pneumonia | 91.54 | 12.56 | 83 | 36177 | 9439 | 29528828 |
Fall | 91.26 | 12.56 | 52 | 36208 | 177126 | 29361141 |
Chronic allograft nephropathy | 89.57 | 12.56 | 38 | 36222 | 1082 | 29537185 |
Apoptosis | 82.13 | 12.56 | 24 | 36236 | 214 | 29538053 |
Proteinuria | 78.69 | 12.56 | 97 | 36163 | 15707 | 29522560 |
Off label use | 75.48 | 12.56 | 627 | 35633 | 300173 | 29238094 |
Lymphocyte count decreased | 75.33 | 12.56 | 105 | 36155 | 19166 | 29519101 |
Fatigue | 74.54 | 12.56 | 175 | 36085 | 316646 | 29221621 |
Klebsiella infection | 74.48 | 12.56 | 66 | 36194 | 7283 | 29530984 |
Strongyloidiasis | 74.08 | 12.56 | 42 | 36218 | 2270 | 29535997 |
Renal impairment | 72.55 | 12.56 | 242 | 36018 | 81091 | 29457176 |
Renal artery stenosis | 72.09 | 12.56 | 39 | 36221 | 1922 | 29536345 |
Rash | 70.90 | 12.56 | 77 | 36183 | 189742 | 29348525 |
Malacoplakia | 70.88 | 12.56 | 19 | 36241 | 119 | 29538148 |
Lymphocele | 70.87 | 12.56 | 34 | 36226 | 1298 | 29536969 |
Focal segmental glomerulosclerosis | 69.40 | 12.56 | 37 | 36223 | 1770 | 29536497 |
Enterococcal infection | 67.83 | 12.56 | 66 | 36194 | 8202 | 29530065 |
Blastomycosis | 67.53 | 12.56 | 22 | 36238 | 290 | 29537977 |
Cystitis haemorrhagic | 66.81 | 12.56 | 52 | 36208 | 4790 | 29533477 |
Pulmonary nocardiosis | 65.27 | 12.56 | 25 | 36235 | 542 | 29537725 |
Septic shock | 64.78 | 12.56 | 196 | 36064 | 62364 | 29475903 |
Acute kidney injury | 64.36 | 12.56 | 549 | 35711 | 264718 | 29273549 |
Histoplasmosis | 64.31 | 12.56 | 32 | 36228 | 1324 | 29536943 |
Pneumonia cryptococcal | 64.29 | 12.56 | 27 | 36233 | 749 | 29537518 |
Liver transplant rejection | 63.62 | 12.56 | 36 | 36224 | 1938 | 29536329 |
Pneumocystis jirovecii pneumonia | 63.47 | 12.56 | 90 | 36170 | 16689 | 29521578 |
Graft loss | 61.99 | 12.56 | 27 | 36233 | 821 | 29537446 |
Aplasia pure red cell | 61.07 | 12.56 | 52 | 36208 | 5439 | 29532828 |
Pneumonia cytomegaloviral | 60.76 | 12.56 | 39 | 36221 | 2643 | 29535624 |
Acinetobacter infection | 60.25 | 12.56 | 28 | 36232 | 994 | 29537273 |
Pain | 60.25 | 12.56 | 73 | 36187 | 171359 | 29366908 |
Red blood cells urine positive | 57.98 | 12.56 | 32 | 36228 | 1641 | 29536626 |
Progressive multifocal leukoencephalopathy | 57.71 | 12.56 | 62 | 36198 | 8657 | 29529610 |
Encephalitis viral | 57.52 | 12.56 | 28 | 36232 | 1104 | 29537163 |
Malignant neoplasm progression | 56.45 | 12.56 | 11 | 36249 | 73848 | 29464419 |
Infection reactivation | 55.57 | 12.56 | 27 | 36233 | 1060 | 29537207 |
Diabetes mellitus | 55.35 | 12.56 | 139 | 36121 | 39692 | 29498575 |
Urinary tract infection | 54.77 | 12.56 | 204 | 36056 | 72150 | 29466117 |
Rhodococcus infection | 53.85 | 12.56 | 16 | 36244 | 152 | 29538115 |
Cytomegalovirus colitis | 53.71 | 12.56 | 35 | 36225 | 2434 | 29535833 |
Pruritus | 53.67 | 12.56 | 39 | 36221 | 116810 | 29421457 |
Dizziness | 52.77 | 12.56 | 95 | 36165 | 189589 | 29348678 |
Polyomavirus viraemia | 51.83 | 12.56 | 22 | 36238 | 627 | 29537640 |
Renal tubular necrosis | 51.53 | 12.56 | 75 | 36185 | 14240 | 29524027 |
Depression | 51.44 | 12.56 | 20 | 36240 | 85127 | 29453140 |
Posterior reversible encephalopathy syndrome | 51.11 | 12.56 | 59 | 36201 | 8917 | 29529350 |
Cryptosporidiosis infection | 50.21 | 12.56 | 19 | 36241 | 398 | 29537869 |
Neutrophil count increased | 49.84 | 12.56 | 75 | 36185 | 14667 | 29523600 |
Adenovirus infection | 49.22 | 12.56 | 42 | 36218 | 4405 | 29533862 |
Scedosporium infection | 47.81 | 12.56 | 22 | 36238 | 763 | 29537504 |
Disseminated cryptococcosis | 47.73 | 12.56 | 25 | 36235 | 1153 | 29537114 |
Alternaria infection | 47.11 | 12.56 | 17 | 36243 | 310 | 29537957 |
Graft versus host disease in lung | 46.82 | 12.56 | 19 | 36241 | 482 | 29537785 |
Haemophagocytic lymphohistiocytosis | 46.79 | 12.56 | 61 | 36199 | 10443 | 29527824 |
Acanthamoeba infection | 46.58 | 12.56 | 18 | 36242 | 400 | 29537867 |
Acute respiratory distress syndrome | 46.42 | 12.56 | 93 | 36167 | 22842 | 29515425 |
Ureteric stenosis | 46.12 | 12.56 | 24 | 36236 | 1092 | 29537175 |
Graft versus host disease in skin | 45.99 | 12.56 | 36 | 36224 | 3343 | 29534924 |
Arthralgia | 45.37 | 12.56 | 63 | 36197 | 139554 | 29398713 |
Protein urine present | 45.28 | 12.56 | 41 | 36219 | 4653 | 29533614 |
Constipation | 45.18 | 12.56 | 44 | 36216 | 114116 | 29424151 |
Brain abscess | 44.40 | 12.56 | 32 | 36228 | 2623 | 29535644 |
Gastroenteritis norovirus | 43.76 | 12.56 | 25 | 36235 | 1371 | 29536896 |
Syncope | 43.10 | 12.56 | 23 | 36237 | 81348 | 29456919 |
Hydronephrosis | 42.51 | 12.56 | 53 | 36207 | 8677 | 29529590 |
Graft versus host disease | 41.47 | 12.56 | 55 | 36205 | 9573 | 29528694 |
Graft versus host disease in gastrointestinal tract | 40.69 | 12.56 | 33 | 36227 | 3225 | 29535042 |
Escherichia urinary tract infection | 40.55 | 12.56 | 32 | 36228 | 3007 | 29535260 |
Trichodysplasia spinulosa | 39.87 | 12.56 | 14 | 36246 | 235 | 29538032 |
Basal cell carcinoma | 39.66 | 12.56 | 73 | 36187 | 16837 | 29521430 |
American trypanosomiasis | 39.59 | 12.56 | 14 | 36246 | 240 | 29538027 |
Escherichia infection | 39.42 | 12.56 | 45 | 36215 | 6719 | 29531548 |
Lymphopenia | 39.02 | 12.56 | 64 | 36196 | 13469 | 29524798 |
Diffuse large B-cell lymphoma | 38.70 | 12.56 | 43 | 36217 | 6233 | 29532034 |
Anxiety | 38.52 | 12.56 | 29 | 36231 | 85336 | 29452931 |
Drug hypersensitivity | 38.23 | 12.56 | 18 | 36242 | 68388 | 29469879 |
Hyperhidrosis | 37.61 | 12.56 | 16 | 36244 | 64524 | 29473743 |
Epstein-Barr viraemia | 37.49 | 12.56 | 20 | 36240 | 958 | 29537309 |
Dermatophytosis | 37.48 | 12.56 | 13 | 36247 | 210 | 29538057 |
Blood urea increased | 36.86 | 12.56 | 96 | 36164 | 28016 | 29510251 |
Squamous cell carcinoma | 35.86 | 12.56 | 53 | 36207 | 10198 | 29528069 |
Pancreas transplant rejection | 35.79 | 12.56 | 12 | 36248 | 174 | 29538093 |
Viraemia | 35.73 | 12.56 | 20 | 36240 | 1054 | 29537213 |
Intraductal papillary mucinous neoplasm | 35.62 | 12.56 | 14 | 36246 | 326 | 29537941 |
Urinoma | 35.17 | 12.56 | 12 | 36248 | 184 | 29538083 |
Pyelonephritis | 35.08 | 12.56 | 38 | 36222 | 5355 | 29532912 |
Dyspnoea | 34.97 | 12.56 | 246 | 36014 | 326486 | 29211781 |
Papilloma viral infection | 34.84 | 12.56 | 15 | 36245 | 443 | 29537824 |
Histoplasmosis disseminated | 34.56 | 12.56 | 20 | 36240 | 1124 | 29537143 |
Renal tubular injury | 34.49 | 12.56 | 17 | 36243 | 689 | 29537578 |
Acute graft versus host disease | 34.37 | 12.56 | 39 | 36221 | 5785 | 29532482 |
Coronavirus infection | 34.25 | 12.56 | 30 | 36230 | 3258 | 29535009 |
Smooth muscle cell neoplasm | 34.05 | 12.56 | 11 | 36249 | 141 | 29538126 |
Histology abnormal | 33.93 | 12.56 | 13 | 36247 | 282 | 29537985 |
Malacoplakia gastrointestinal | 33.66 | 12.56 | 10 | 36250 | 95 | 29538172 |
Decreased appetite | 33.46 | 12.56 | 81 | 36179 | 145261 | 29393006 |
Somnolence | 32.96 | 12.56 | 40 | 36220 | 93915 | 29444352 |
Respiratory failure | 32.43 | 12.56 | 217 | 36043 | 96914 | 29441353 |
Candida infection | 32.33 | 12.56 | 63 | 36197 | 15162 | 29523105 |
Chronic graft versus host disease in skin | 32.02 | 12.56 | 17 | 36243 | 806 | 29537461 |
Chronic graft versus host disease in liver | 31.96 | 12.56 | 13 | 36247 | 332 | 29537935 |
Squamous cell carcinoma of skin | 31.69 | 12.56 | 48 | 36212 | 9438 | 29528829 |
Chronic obstructive pulmonary disease | 31.49 | 12.56 | 6 | 36254 | 40949 | 29497318 |
Trichophytosis | 31.25 | 12.56 | 12 | 36248 | 262 | 29538005 |
Renal transplant | 30.54 | 12.56 | 21 | 36239 | 1597 | 29536670 |
Graft versus host disease in liver | 30.21 | 12.56 | 18 | 36242 | 1068 | 29537199 |
Mycobacterial infection | 30.20 | 12.56 | 22 | 36238 | 1834 | 29536433 |
Varicella zoster virus infection | 29.97 | 12.56 | 20 | 36240 | 1448 | 29536819 |
Myocardial infarction | 29.95 | 12.56 | 56 | 36204 | 110240 | 29428027 |
Meningitis cryptococcal | 29.95 | 12.56 | 23 | 36237 | 2077 | 29536190 |
Necrotising oesophagitis | 29.84 | 12.56 | 14 | 36246 | 508 | 29537759 |
Epistaxis | 29.83 | 12.56 | 13 | 36247 | 51691 | 29486576 |
Donor specific antibody present | 29.79 | 12.56 | 9 | 36251 | 91 | 29538176 |
Pyelonephritis acute | 29.78 | 12.56 | 21 | 36239 | 1663 | 29536604 |
Immune reconstitution inflammatory syndrome | 29.72 | 12.56 | 42 | 36218 | 7760 | 29530507 |
Febrile neutropenia | 29.59 | 12.56 | 58 | 36202 | 112182 | 29426085 |
Large intestinal ulcer | 29.50 | 12.56 | 21 | 36239 | 1688 | 29536579 |
Heart transplant rejection | 29.24 | 12.56 | 18 | 36242 | 1133 | 29537134 |
Intentional product misuse | 29.06 | 12.56 | 4 | 36256 | 34657 | 29503610 |
Erythema | 28.91 | 12.56 | 30 | 36230 | 75576 | 29462691 |
Postoperative thoracic procedure complication | 28.71 | 12.56 | 7 | 36253 | 28 | 29538239 |
Cardiac failure congestive | 28.59 | 12.56 | 31 | 36229 | 76550 | 29461717 |
Neutrophil count decreased | 28.42 | 12.56 | 9 | 36251 | 43558 | 29494709 |
Pneumonia escherichia | 27.95 | 12.56 | 12 | 36248 | 352 | 29537915 |
Rectal prolapse | 27.83 | 12.56 | 11 | 36249 | 260 | 29538007 |
Meningoencephalitis amoebic | 27.74 | 12.56 | 9 | 36251 | 117 | 29538150 |
Isosporiasis | 27.72 | 12.56 | 8 | 36252 | 68 | 29538199 |
Hernial eventration | 27.72 | 12.56 | 8 | 36252 | 68 | 29538199 |
Asthenia | 27.67 | 12.56 | 153 | 36107 | 215097 | 29323170 |
Coronary artery disease | 27.31 | 12.56 | 10 | 36250 | 44180 | 29494087 |
Gastroenteritis sapovirus | 27.07 | 12.56 | 9 | 36251 | 127 | 29538140 |
Epstein-Barr virus associated lymphoproliferative disorder | 26.92 | 12.56 | 20 | 36240 | 1718 | 29536549 |
Renal cyst haemorrhage | 26.72 | 12.56 | 12 | 36248 | 393 | 29537874 |
Malaise | 26.70 | 12.56 | 103 | 36157 | 159499 | 29378768 |
Acute myocardial infarction | 26.67 | 12.56 | 13 | 36247 | 48425 | 29489842 |
Cerebral aspergillosis | 26.54 | 12.56 | 18 | 36242 | 1338 | 29536929 |
Hypersensitivity | 26.50 | 12.56 | 16 | 36244 | 52887 | 29485380 |
Vena cava injury | 26.49 | 12.56 | 10 | 36250 | 208 | 29538059 |
Ventricular remodelling | 26.29 | 12.56 | 8 | 36252 | 83 | 29538184 |
Neuropathy peripheral | 26.24 | 12.56 | 29 | 36231 | 70998 | 29467269 |
Nausea | 26.14 | 12.56 | 228 | 36032 | 289027 | 29249240 |
SARS-CoV-2 antibody test positive | 25.84 | 12.56 | 10 | 36250 | 223 | 29538044 |
Anogenital warts | 25.81 | 12.56 | 13 | 36247 | 552 | 29537715 |
Renal vein thrombosis | 25.74 | 12.56 | 9 | 36251 | 149 | 29538118 |
Human herpesvirus 6 infection | 25.68 | 12.56 | 20 | 36240 | 1843 | 29536424 |
Chronic graft versus host disease | 25.52 | 12.56 | 28 | 36232 | 4001 | 29534266 |
Wrong technique in product usage process | 25.49 | 12.56 | 4 | 36256 | 31424 | 29506843 |
Urticaria | 25.39 | 12.56 | 18 | 36242 | 54642 | 29483625 |
Transplantation complication | 25.32 | 12.56 | 8 | 36252 | 95 | 29538172 |
Actinic keratosis | 25.19 | 12.56 | 27 | 36233 | 3759 | 29534508 |
Renal graft infection | 25.16 | 12.56 | 10 | 36250 | 240 | 29538027 |
Glomerulonephritis | 25.08 | 12.56 | 19 | 36241 | 1681 | 29536586 |
Encephalitis | 25.06 | 12.56 | 35 | 36225 | 6395 | 29531872 |
Hypotension | 25.05 | 12.56 | 138 | 36122 | 194216 | 29344051 |
Perinephric collection | 25.00 | 12.56 | 9 | 36251 | 163 | 29538104 |
Non-cirrhotic portal hypertension | 24.93 | 12.56 | 10 | 36250 | 246 | 29538021 |
Gastrointestinal mucormycosis | 24.52 | 12.56 | 8 | 36252 | 106 | 29538161 |
Drug interaction | 24.38 | 12.56 | 358 | 35902 | 197027 | 29341240 |
Procedural pain | 24.33 | 12.56 | 28 | 36232 | 4216 | 29534051 |
Immunosuppressant drug level decreased | 24.18 | 12.56 | 16 | 36244 | 1142 | 29537125 |
Hyperkalaemia | 24.11 | 12.56 | 143 | 36117 | 61249 | 29477018 |
Foetal exposure during pregnancy | 23.93 | 12.56 | 6 | 36254 | 33861 | 29504406 |
Blood pressure decreased | 23.85 | 12.56 | 13 | 36247 | 45464 | 29492803 |
Diarrhoea | 23.80 | 12.56 | 554 | 35706 | 332144 | 29206123 |
Cholangitis | 23.58 | 12.56 | 37 | 36223 | 7500 | 29530767 |
Muscle spasms | 23.58 | 12.56 | 27 | 36233 | 65055 | 29473212 |
Glomerulonephritis membranoproliferative | 23.55 | 12.56 | 11 | 36249 | 395 | 29537872 |
Joint swelling | 23.50 | 12.56 | 16 | 36244 | 49614 | 29488653 |
Mycobacterium haemophilum infection | 23.36 | 12.56 | 6 | 36254 | 31 | 29538236 |
Cytomegalovirus oesophagitis | 23.29 | 12.56 | 11 | 36249 | 405 | 29537862 |
Meningoencephalitis viral | 23.19 | 12.56 | 8 | 36252 | 127 | 29538140 |
Urinary tract infection bacterial | 23.08 | 12.56 | 17 | 36243 | 1441 | 29536826 |
Cardio-respiratory arrest | 23.06 | 12.56 | 17 | 36243 | 50584 | 29487683 |
Inappropriate schedule of product administration | 22.91 | 12.56 | 13 | 36247 | 44459 | 29493808 |
Corynebacterium infection | 22.90 | 12.56 | 11 | 36249 | 421 | 29537846 |
Vesicoureteral reflux surgery | 22.82 | 12.56 | 4 | 36256 | 0 | 29538267 |
Myopathy toxic | 22.78 | 12.56 | 11 | 36249 | 426 | 29537841 |
Postoperative wound infection | 22.71 | 12.56 | 27 | 36233 | 4209 | 29534058 |
Seroma | 22.57 | 12.56 | 12 | 36248 | 571 | 29537696 |
Parvovirus infection | 22.50 | 12.56 | 11 | 36249 | 438 | 29537829 |
Fungal infection | 22.49 | 12.56 | 51 | 36209 | 13634 | 29524633 |
Insomnia | 22.42 | 12.56 | 47 | 36213 | 88714 | 29449553 |
Nasal cavity cancer | 22.37 | 12.56 | 8 | 36252 | 142 | 29538125 |
Haemolytic uraemic syndrome | 22.36 | 12.56 | 19 | 36241 | 1981 | 29536286 |
Blood creatine phosphokinase increased | 22.23 | 12.56 | 11 | 36249 | 40633 | 29497634 |
Bacterial infection | 22.12 | 12.56 | 49 | 36211 | 12899 | 29525368 |
Pain in extremity | 22.04 | 12.56 | 66 | 36194 | 110367 | 29427900 |
Disseminated mucormycosis | 22.03 | 12.56 | 10 | 36250 | 336 | 29537931 |
Renal tubular acidosis | 21.96 | 12.56 | 18 | 36242 | 1785 | 29536482 |
Philadelphia positive chronic myeloid leukaemia | 21.86 | 12.56 | 7 | 36253 | 87 | 29538180 |
Aortic pseudoaneurysm | 21.81 | 12.56 | 6 | 36254 | 42 | 29538225 |
Bacterial pyelonephritis | 21.66 | 12.56 | 9 | 36251 | 243 | 29538024 |
Catatonia | 21.55 | 12.56 | 27 | 36233 | 4441 | 29533826 |
Cutaneous malacoplakia | 21.45 | 12.56 | 6 | 36254 | 45 | 29538222 |
International normalised ratio increased | 21.42 | 12.56 | 14 | 36246 | 44358 | 29493909 |
Histoplasmosis cutaneous | 21.14 | 12.56 | 5 | 36255 | 17 | 29538250 |
Pneumonia pseudomonal | 21.10 | 12.56 | 23 | 36237 | 3264 | 29535003 |
Pneumocystis jirovecii infection | 20.96 | 12.56 | 16 | 36244 | 1432 | 29536835 |
Human herpesvirus 8 infection | 20.89 | 12.56 | 13 | 36247 | 834 | 29537433 |
Tubulointerstitial nephritis | 20.86 | 12.56 | 58 | 36202 | 17585 | 29520682 |
Infective aortitis | 20.71 | 12.56 | 5 | 36255 | 19 | 29538248 |
Musculoskeletal stiffness | 20.70 | 12.56 | 10 | 36250 | 37448 | 29500819 |
Metastatic squamous cell carcinoma | 20.67 | 12.56 | 10 | 36250 | 389 | 29537878 |
Seizure | 20.55 | 12.56 | 53 | 36207 | 93070 | 29445197 |
Infected lymphocele | 20.50 | 12.56 | 5 | 36255 | 20 | 29538247 |
Back pain | 20.50 | 12.56 | 61 | 36199 | 102223 | 29436044 |
Product dose omission issue | 20.41 | 12.56 | 56 | 36204 | 96327 | 29441940 |
Asthma | 20.35 | 12.56 | 8 | 36252 | 33841 | 29504426 |
Lung transplant | 20.28 | 12.56 | 17 | 36243 | 1739 | 29536528 |
Pathogen resistance | 20.25 | 12.56 | 36 | 36224 | 8080 | 29530187 |
Lung transplant rejection | 20.14 | 12.56 | 12 | 36248 | 712 | 29537555 |
Leishmaniasis | 20.06 | 12.56 | 9 | 36251 | 294 | 29537973 |
Necrotising fasciitis fungal | 19.94 | 12.56 | 5 | 36255 | 23 | 29538244 |
Prophylaxis against transplant rejection | 19.94 | 12.56 | 5 | 36255 | 23 | 29538244 |
Paraesthesia | 19.87 | 12.56 | 22 | 36238 | 53823 | 29484444 |
Platelet count decreased | 19.86 | 12.56 | 64 | 36196 | 104608 | 29433659 |
Hypoglycaemia | 19.85 | 12.56 | 18 | 36242 | 48328 | 29489939 |
Anti-erythropoietin antibody negative | 19.71 | 12.56 | 8 | 36252 | 203 | 29538064 |
Drug reaction with eosinophilia and systemic symptoms | 19.70 | 12.56 | 5 | 36255 | 27987 | 29510280 |
Intra-abdominal haemorrhage | 19.62 | 12.56 | 18 | 36242 | 2077 | 29536190 |
Suicidal ideation | 19.60 | 12.56 | 9 | 36251 | 34707 | 29503560 |
Disease recurrence | 19.49 | 12.56 | 53 | 36207 | 15861 | 29522406 |
Electrocardiogram QT prolonged | 19.44 | 12.56 | 10 | 36250 | 36127 | 29502140 |
Alveolar proteinosis | 19.43 | 12.56 | 9 | 36251 | 317 | 29537950 |
Optic discs blurred | 19.24 | 12.56 | 6 | 36254 | 68 | 29538199 |
Metabolic acidosis | 19.03 | 12.56 | 94 | 36166 | 37568 | 29500699 |
Suicide attempt | 19.01 | 12.56 | 9 | 36251 | 34101 | 29504166 |
Chest pain | 18.88 | 12.56 | 72 | 36188 | 111901 | 29426366 |
Mediastinitis | 18.81 | 12.56 | 11 | 36249 | 630 | 29537637 |
Depressed level of consciousness | 18.74 | 12.56 | 11 | 36249 | 36931 | 29501336 |
Urosepsis | 18.73 | 12.56 | 41 | 36219 | 10705 | 29527562 |
Cytomegalovirus mucocutaneous ulcer | 18.71 | 12.56 | 6 | 36254 | 75 | 29538192 |
Secondary immunodeficiency | 18.70 | 12.56 | 9 | 36251 | 346 | 29537921 |
Mouth ulceration | 18.61 | 12.56 | 40 | 36220 | 10315 | 29527952 |
Post procedural urine leak | 18.52 | 12.56 | 7 | 36253 | 146 | 29538121 |
Impaired healing | 18.49 | 12.56 | 47 | 36213 | 13511 | 29524756 |
Hemianopia heteronymous | 18.43 | 12.56 | 5 | 36255 | 33 | 29538234 |
Heart rate decreased | 18.42 | 12.56 | 4 | 36256 | 24908 | 29513359 |
IgA nephropathy | 18.26 | 12.56 | 13 | 36247 | 1045 | 29537222 |
Visceral leishmaniasis | 18.24 | 12.56 | 10 | 36250 | 506 | 29537761 |
Neurotoxicity | 18.23 | 12.56 | 49 | 36211 | 14564 | 29523703 |
Feeling abnormal | 18.23 | 12.56 | 24 | 36236 | 54421 | 29483846 |
Periostitis | 18.19 | 12.56 | 8 | 36252 | 249 | 29538018 |
Anorectal varices | 18.17 | 12.56 | 5 | 36255 | 35 | 29538232 |
Enterobacter infection | 18.13 | 12.56 | 17 | 36243 | 2017 | 29536250 |
Complications of transplanted heart | 18.04 | 12.56 | 8 | 36252 | 254 | 29538013 |
Haemoglobinaemia | 17.97 | 12.56 | 7 | 36253 | 159 | 29538108 |
Disseminated varicella zoster virus infection | 17.97 | 12.56 | 7 | 36253 | 159 | 29538108 |
Eccrine squamous syringometaplasia | 17.93 | 12.56 | 5 | 36255 | 37 | 29538230 |
Acute graft versus host disease in intestine | 17.92 | 12.56 | 18 | 36242 | 2323 | 29535944 |
Acute graft versus host disease in skin | 17.60 | 12.56 | 25 | 36235 | 4639 | 29533628 |
Fungal skin infection | 17.56 | 12.56 | 18 | 36242 | 2380 | 29535887 |
Incisional hernia | 17.54 | 12.56 | 13 | 36247 | 1113 | 29537154 |
Aggression | 17.45 | 12.56 | 11 | 36249 | 35530 | 29502737 |
Bacterial sepsis | 17.44 | 12.56 | 25 | 36235 | 4678 | 29533589 |
Hyperparathyroidism | 17.42 | 12.56 | 13 | 36247 | 1124 | 29537143 |
Acinetobacter bacteraemia | 17.29 | 12.56 | 6 | 36254 | 97 | 29538170 |
Retinal artery occlusion | 17.29 | 12.56 | 15 | 36245 | 1608 | 29536659 |
Transmission of an infectious agent via transplant | 17.29 | 12.56 | 4 | 36256 | 12 | 29538255 |
Delusion of grandeur | 17.12 | 12.56 | 9 | 36251 | 418 | 29537849 |
Ureteral catheterisation | 17.12 | 12.56 | 3 | 36257 | 0 | 29538267 |
Biliary anastomosis complication | 17.01 | 12.56 | 6 | 36254 | 102 | 29538165 |
Cardiac failure | 16.83 | 12.56 | 46 | 36214 | 79241 | 29459026 |
Hallucination | 16.79 | 12.56 | 18 | 36242 | 44694 | 29493573 |
Mycobacterium chelonae infection | 16.71 | 12.56 | 10 | 36250 | 598 | 29537669 |
Balance disorder | 16.68 | 12.56 | 12 | 36248 | 36158 | 29502109 |
End stage renal disease | 16.62 | 12.56 | 32 | 36228 | 7632 | 29530635 |
Urinary fistula | 16.60 | 12.56 | 6 | 36254 | 110 | 29538157 |
Nephrostomy | 16.57 | 12.56 | 7 | 36253 | 197 | 29538070 |
Glomerulonephritis proliferative | 16.47 | 12.56 | 7 | 36253 | 200 | 29538067 |
Multiple organ dysfunction syndrome | 16.46 | 12.56 | 133 | 36127 | 62983 | 29475284 |
Loss of consciousness | 16.45 | 12.56 | 42 | 36218 | 74014 | 29464253 |
Cytomegalovirus nephritis | 16.25 | 12.56 | 6 | 36254 | 117 | 29538150 |
Pneumonia klebsiella | 16.10 | 12.56 | 18 | 36242 | 2626 | 29535641 |
Renal lymphocele | 16.09 | 12.56 | 5 | 36255 | 56 | 29538211 |
Diverticulum intestinal | 16.06 | 12.56 | 20 | 36240 | 3270 | 29534997 |
Dysgeusia | 16.05 | 12.56 | 4 | 36256 | 22670 | 29515597 |
Argentine haemorrhagic fever | 16.02 | 12.56 | 4 | 36256 | 18 | 29538249 |
Gait disturbance | 15.98 | 12.56 | 42 | 36218 | 73307 | 29464960 |
Oesophageal stenosis | 15.98 | 12.56 | 14 | 36246 | 1521 | 29536746 |
Chronic hepatitis C | 15.94 | 12.56 | 8 | 36252 | 337 | 29537930 |
Agitation | 15.80 | 12.56 | 24 | 36236 | 51280 | 29486987 |
Respiratory arrest | 15.70 | 12.56 | 6 | 36254 | 25827 | 29512440 |
Human polyomavirus infection | 15.53 | 12.56 | 10 | 36250 | 681 | 29537586 |
Rhabdomyolysis | 15.51 | 12.56 | 32 | 36228 | 60776 | 29477491 |
Staphylococcal infection | 15.50 | 12.56 | 74 | 36186 | 29166 | 29509101 |
Upper gastrointestinal haemorrhage | 15.26 | 12.56 | 4 | 36256 | 21910 | 29516357 |
Chronic kidney disease-mineral and bone disorder | 15.25 | 12.56 | 8 | 36252 | 370 | 29537897 |
Lymphorrhoea | 15.20 | 12.56 | 5 | 36255 | 68 | 29538199 |
Cardiac disorder | 15.14 | 12.56 | 14 | 36246 | 37249 | 29501018 |
White blood cell count decreased | 15.10 | 12.56 | 52 | 36208 | 83310 | 29454957 |
Pyrexia | 15.06 | 12.56 | 460 | 35800 | 287162 | 29251105 |
Serratia infection | 15.06 | 12.56 | 10 | 36250 | 718 | 29537549 |
Abdominal wall haemorrhage | 15.05 | 12.56 | 7 | 36253 | 249 | 29538018 |
Balamuthia infection | 15.04 | 12.56 | 3 | 36257 | 3 | 29538264 |
Propionibacterium infection | 14.97 | 12.56 | 7 | 36253 | 252 | 29538015 |
Gastrointestinal mucosa hyperaemia | 14.82 | 12.56 | 7 | 36253 | 258 | 29538009 |
Graft thrombosis | 14.82 | 12.56 | 7 | 36253 | 258 | 29538009 |
Pupillary deformity | 14.79 | 12.56 | 4 | 36256 | 26 | 29538241 |
Lymphadenitis fungal | 14.58 | 12.56 | 3 | 36257 | 4 | 29538263 |
Epstein-Barr virus associated lymphoma | 14.56 | 12.56 | 9 | 36251 | 571 | 29537696 |
Vocal cord thickening | 14.54 | 12.56 | 4 | 36256 | 28 | 29538239 |
Cranial nerve paralysis | 14.42 | 12.56 | 4 | 36256 | 29 | 29538238 |
Rheumatoid arthritis | 14.39 | 12.56 | 11 | 36249 | 32141 | 29506126 |
Herpes zoster cutaneous disseminated | 14.33 | 12.56 | 6 | 36254 | 165 | 29538102 |
Hospitalisation | 14.29 | 12.56 | 101 | 36159 | 45887 | 29492380 |
Peripheral swelling | 14.27 | 12.56 | 36 | 36224 | 63703 | 29474564 |
Injury | 14.20 | 12.56 | 3 | 36257 | 19043 | 29519224 |
Flushing | 14.19 | 12.56 | 9 | 36251 | 28983 | 29509284 |
New onset diabetes after transplantation | 14.18 | 12.56 | 4 | 36256 | 31 | 29538236 |
Wound dehiscence | 14.18 | 12.56 | 18 | 36242 | 2999 | 29535268 |
Bilirubin conjugated increased | 14.18 | 12.56 | 18 | 36242 | 2999 | 29535268 |
Angioedema | 14.18 | 12.56 | 11 | 36249 | 31904 | 29506363 |
Leuconostoc infection | 14.18 | 12.56 | 3 | 36257 | 5 | 29538262 |
Arteriovenous fistula aneurysm | 14.18 | 12.56 | 3 | 36257 | 5 | 29538262 |
Gastroenteritis cryptosporidial | 14.17 | 12.56 | 6 | 36254 | 170 | 29538097 |
Brain compression | 14.10 | 12.56 | 6 | 36254 | 172 | 29538095 |
Functional gastrointestinal disorder | 14.07 | 12.56 | 15 | 36245 | 2075 | 29536192 |
Pancreas transplant | 14.07 | 12.56 | 4 | 36256 | 32 | 29538235 |
Nephrosclerosis | 14.05 | 12.56 | 10 | 36250 | 804 | 29537463 |
Hyperparathyroidism secondary | 14.02 | 12.56 | 12 | 36248 | 1263 | 29537004 |
Herpes simplex hepatitis | 14.02 | 12.56 | 5 | 36255 | 88 | 29538179 |
Neuroendocrine carcinoma of the skin | 14.00 | 12.56 | 9 | 36251 | 611 | 29537656 |
Pyuria | 13.80 | 12.56 | 9 | 36251 | 627 | 29537640 |
Legionella infection | 13.77 | 12.56 | 8 | 36252 | 453 | 29537814 |
Immunoglobulin G4 related disease | 13.76 | 12.56 | 4 | 36256 | 35 | 29538232 |
Abdominal wall abscess | 13.72 | 12.56 | 8 | 36252 | 456 | 29537811 |
Oesophageal ulcer | 13.71 | 12.56 | 18 | 36242 | 3102 | 29535165 |
Passenger lymphocyte syndrome | 13.56 | 12.56 | 4 | 36256 | 37 | 29538230 |
Scleroderma | 13.52 | 12.56 | 12 | 36248 | 1326 | 29536941 |
Drug level fluctuating | 13.36 | 12.56 | 8 | 36252 | 479 | 29537788 |
Capillaritis | 13.29 | 12.56 | 5 | 36255 | 103 | 29538164 |
Enterovirus infection | 13.28 | 12.56 | 9 | 36251 | 668 | 29537599 |
Drug resistance | 13.27 | 12.56 | 57 | 36203 | 21483 | 29516784 |
Confusional state | 13.26 | 12.56 | 97 | 36163 | 127780 | 29410487 |
Endocarditis viral | 13.23 | 12.56 | 3 | 36257 | 8 | 29538259 |
Transitional cell carcinoma | 13.23 | 12.56 | 14 | 36246 | 1921 | 29536346 |
Nodular regenerative hyperplasia | 13.21 | 12.56 | 9 | 36251 | 674 | 29537593 |
Cytomegalovirus gastroenteritis | 13.21 | 12.56 | 6 | 36254 | 202 | 29538065 |
Bordetella infection | 13.20 | 12.56 | 5 | 36255 | 105 | 29538162 |
Gingival hypertrophy | 13.11 | 12.56 | 13 | 36247 | 1652 | 29536615 |
Drug withdrawal syndrome | 13.07 | 12.56 | 3 | 36257 | 17981 | 29520286 |
Biopsy kidney abnormal | 12.98 | 12.56 | 5 | 36255 | 110 | 29538157 |
Pneumonia proteus | 12.97 | 12.56 | 3 | 36257 | 9 | 29538258 |
Small intestine gangrene | 12.97 | 12.56 | 3 | 36257 | 9 | 29538258 |
Disease progression | 12.96 | 12.56 | 54 | 36206 | 81862 | 29456405 |
Herpes zoster oticus | 12.94 | 12.56 | 5 | 36255 | 111 | 29538156 |
Phaeohyphomycotic brain abscess | 12.94 | 12.56 | 4 | 36256 | 44 | 29538223 |
Cytomegalovirus gastritis | 12.94 | 12.56 | 6 | 36254 | 212 | 29538055 |
Cytomegalovirus syndrome | 12.90 | 12.56 | 5 | 36255 | 112 | 29538155 |
Toxoplasmosis | 12.87 | 12.56 | 11 | 36249 | 1156 | 29537111 |
Streptococcal endocarditis | 12.85 | 12.56 | 4 | 36256 | 45 | 29538222 |
Superinfection bacterial | 12.83 | 12.56 | 9 | 36251 | 707 | 29537560 |
Liver transplant | 12.81 | 12.56 | 15 | 36245 | 2301 | 29535966 |
Stomatitis | 12.79 | 12.56 | 16 | 36244 | 37097 | 29501170 |
Carotid arteriosclerosis | 12.78 | 12.56 | 12 | 36248 | 1426 | 29536841 |
Stenotrophomonas infection | 12.77 | 12.56 | 13 | 36247 | 1704 | 29536563 |
Narrow anterior chamber angle | 12.74 | 12.56 | 5 | 36255 | 116 | 29538151 |
Chemical peritonitis | 12.66 | 12.56 | 5 | 36255 | 118 | 29538149 |
Central nervous system lymphoma | 12.63 | 12.56 | 9 | 36251 | 725 | 29537542 |
Cerebrovascular accident | 12.60 | 12.56 | 50 | 36210 | 76861 | 29461406 |
Urine output decreased | 12.57 | 12.56 | 32 | 36228 | 9206 | 29529061 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Cytomegalovirus infection | 1119.03 | 11.27 | 587 | 58656 | 36612 | 64402877 |
Kidney transplant rejection | 870.78 | 11.27 | 328 | 58915 | 9183 | 64430306 |
Transplant rejection | 857.10 | 11.27 | 385 | 58858 | 17016 | 64422473 |
Post transplant lymphoproliferative disorder | 664.77 | 11.27 | 270 | 58973 | 9274 | 64430215 |
Complications of transplanted kidney | 599.36 | 11.27 | 215 | 59028 | 5220 | 64434269 |
COVID-19 | 593.38 | 11.27 | 486 | 58757 | 64654 | 64374835 |
Polyomavirus-associated nephropathy | 511.43 | 11.27 | 186 | 59057 | 4702 | 64434787 |
Immunosuppressant drug level increased | 407 | 11.27 | 176 | 59067 | 7083 | 64432406 |
BK virus infection | 406.73 | 11.27 | 177 | 59066 | 7235 | 64432254 |
Thrombotic microangiopathy | 374.17 | 11.27 | 217 | 59026 | 16438 | 64423051 |
Cytomegalovirus viraemia | 337.01 | 11.27 | 175 | 59068 | 10653 | 64428836 |
Product use in unapproved indication | 321.37 | 11.27 | 579 | 58664 | 176039 | 64263450 |
Delayed graft function | 286.14 | 11.27 | 107 | 59136 | 2929 | 64436560 |
Epstein-Barr virus infection | 262.82 | 11.27 | 156 | 59087 | 12332 | 64427157 |
Parvovirus B19 infection | 261.41 | 11.27 | 80 | 59163 | 1159 | 64438330 |
Transplant dysfunction | 260.55 | 11.27 | 126 | 59117 | 6582 | 64432907 |
Leukopenia | 259.98 | 11.27 | 388 | 58855 | 100854 | 64338635 |
Blood creatinine increased | 245.36 | 11.27 | 444 | 58799 | 135338 | 64304151 |
Renal transplant failure | 239.35 | 11.27 | 80 | 59163 | 1560 | 64437929 |
Aspergillus infection | 238.24 | 11.27 | 162 | 59081 | 16217 | 64423272 |
Off label use | 218.71 | 11.27 | 1150 | 58093 | 631656 | 63807833 |
West Nile viral infection | 205.40 | 11.27 | 62 | 59181 | 855 | 64438634 |
JC virus infection | 193.49 | 11.27 | 83 | 59160 | 3272 | 64436217 |
Posterior reversible encephalopathy syndrome | 191.68 | 11.27 | 163 | 59080 | 22783 | 64416706 |
Cryptococcosis | 188.56 | 11.27 | 77 | 59166 | 2678 | 64436811 |
Renal impairment | 175.74 | 11.27 | 385 | 58858 | 134632 | 64304857 |
Pneumocystis jirovecii pneumonia | 169.41 | 11.27 | 165 | 59078 | 27469 | 64412020 |
Drug level increased | 162.36 | 11.27 | 178 | 59065 | 34018 | 64405471 |
Nephropathy toxic | 162.03 | 11.27 | 132 | 59111 | 17382 | 64422107 |
Phaeohyphomycosis | 155.18 | 11.27 | 52 | 59191 | 1022 | 64438467 |
Chronic allograft nephropathy | 152.12 | 11.27 | 56 | 59187 | 1465 | 64438024 |
Apoptosis | 151.70 | 11.27 | 39 | 59204 | 283 | 64439206 |
Incision site pain | 147.61 | 11.27 | 64 | 59179 | 2590 | 64436899 |
Bronchopulmonary aspergillosis | 144.11 | 11.27 | 128 | 59115 | 18957 | 64420532 |
Fall | 143.98 | 11.27 | 104 | 59139 | 416722 | 64022767 |
Nocardiosis | 142.48 | 11.27 | 75 | 59168 | 4692 | 64434797 |
Pain | 142.43 | 11.27 | 180 | 59063 | 553331 | 63886158 |
Fatigue | 140.12 | 11.27 | 300 | 58943 | 748430 | 63691059 |
Mucormycosis | 137.20 | 11.27 | 85 | 59158 | 7256 | 64432233 |
Acute kidney injury | 136.93 | 11.27 | 790 | 58453 | 448450 | 63991039 |
Graft versus host disease in skin | 134.40 | 11.27 | 75 | 59168 | 5272 | 64434217 |
Histoplasmosis | 133.23 | 11.27 | 55 | 59188 | 1967 | 64437522 |
Epstein-Barr viraemia | 129.08 | 11.27 | 52 | 59191 | 1745 | 64437744 |
Graft versus host disease in gastrointestinal tract | 128.34 | 11.27 | 74 | 59169 | 5538 | 64433951 |
Histoplasmosis disseminated | 127.10 | 11.27 | 53 | 59190 | 1945 | 64437544 |
Lymphocele | 126.61 | 11.27 | 50 | 59193 | 1591 | 64437898 |
Focal segmental glomerulosclerosis | 125.61 | 11.27 | 59 | 59184 | 2885 | 64436604 |
Pseudomonas infection | 123.36 | 11.27 | 114 | 59129 | 17769 | 64421720 |
Graft loss | 123.03 | 11.27 | 43 | 59200 | 964 | 64438525 |
Blastomycosis | 121.92 | 11.27 | 36 | 59207 | 458 | 64439031 |
Trichodysplasia spinulosa | 120.89 | 11.27 | 39 | 59204 | 677 | 64438812 |
Adenovirus infection | 120.59 | 11.27 | 78 | 59165 | 7177 | 64432312 |
Transplant failure | 119.99 | 11.27 | 62 | 59181 | 3732 | 64435757 |
Varicella zoster virus infection | 118.56 | 11.27 | 62 | 59181 | 3826 | 64435663 |
Klebsiella infection | 118.46 | 11.27 | 98 | 59145 | 13183 | 64426306 |
Renal tubular atrophy | 115.92 | 11.27 | 46 | 59197 | 1483 | 64438006 |
Aplasia pure red cell | 115.58 | 11.27 | 75 | 59168 | 6939 | 64432550 |
Kidney fibrosis | 113.68 | 11.27 | 56 | 59187 | 3045 | 64436444 |
Liver transplant rejection | 112.45 | 11.27 | 55 | 59188 | 2944 | 64436545 |
Cytomegalovirus colitis | 112.31 | 11.27 | 60 | 59183 | 3868 | 64435621 |
Arthralgia | 111.40 | 11.27 | 146 | 59097 | 442114 | 63997375 |
Escherichia infection | 109.13 | 11.27 | 99 | 59144 | 15069 | 64424420 |
Polyomavirus viraemia | 106.03 | 11.27 | 40 | 59203 | 1122 | 64438367 |
Hepatitis E | 104.59 | 11.27 | 49 | 59194 | 2382 | 64437107 |
Rash | 104.01 | 11.27 | 163 | 59080 | 458386 | 63981103 |
Septic shock | 102.91 | 11.27 | 269 | 58974 | 105168 | 64334321 |
Cystitis haemorrhagic | 102.36 | 11.27 | 73 | 59170 | 7883 | 64431606 |
Enterococcal infection | 100.73 | 11.27 | 91 | 59152 | 13775 | 64425714 |
COVID-19 pneumonia | 100.12 | 11.27 | 98 | 59145 | 16406 | 64423083 |
Diabetes mellitus | 99.71 | 11.27 | 201 | 59042 | 66273 | 64373216 |
Proteinuria | 97.84 | 11.27 | 124 | 59119 | 27599 | 64411890 |
Diffuse large B-cell lymphoma | 97.75 | 11.27 | 79 | 59164 | 10282 | 64429207 |
Progressive multifocal leukoencephalopathy | 97.30 | 11.27 | 101 | 59142 | 18131 | 64421358 |
Strongyloidiasis | 93.44 | 11.27 | 49 | 59194 | 3041 | 64436448 |
Renal tubular necrosis | 91.18 | 11.27 | 107 | 59136 | 22003 | 64417486 |
Disseminated cryptococcosis | 91.13 | 11.27 | 39 | 59204 | 1528 | 64437961 |
Respiratory failure | 91.04 | 11.27 | 340 | 58903 | 160843 | 64278646 |
Drug hypersensitivity | 90.61 | 11.27 | 53 | 59190 | 237762 | 64201727 |
Malacoplakia | 88.01 | 11.27 | 24 | 59219 | 224 | 64439265 |
Human herpesvirus 6 infection | 87.25 | 11.27 | 54 | 59189 | 4600 | 64434889 |
Haemophagocytic lymphohistiocytosis | 85.90 | 11.27 | 93 | 59150 | 17516 | 64421973 |
Multiple organ dysfunction syndrome | 85.27 | 11.27 | 245 | 58998 | 101168 | 64338321 |
Pruritus | 83.96 | 11.27 | 98 | 59145 | 312302 | 64127187 |
Rhodococcus infection | 83.28 | 11.27 | 23 | 59220 | 226 | 64439263 |
Dizziness | 83.02 | 11.27 | 169 | 59074 | 429994 | 64009495 |
Acute respiratory distress syndrome | 82.85 | 11.27 | 137 | 59106 | 38798 | 64400691 |
Graft versus host disease | 81.89 | 11.27 | 81 | 59162 | 13732 | 64425757 |
Pneumonia cytomegaloviral | 80.47 | 11.27 | 50 | 59193 | 4289 | 64435200 |
Infection reactivation | 78.43 | 11.27 | 38 | 59205 | 1992 | 64437497 |
Tubulointerstitial nephritis | 77.14 | 11.27 | 117 | 59126 | 30792 | 64408697 |
Arthropathy | 77.12 | 11.27 | 10 | 59233 | 120957 | 64318532 |
Neutrophil count increased | 75.55 | 11.27 | 104 | 59139 | 25070 | 64414419 |
Brain abscess | 74.57 | 11.27 | 47 | 59196 | 4134 | 64435355 |
Lymphocyte count decreased | 74.53 | 11.27 | 134 | 59109 | 40565 | 64398924 |
Injection site pain | 71.53 | 11.27 | 9 | 59234 | 111399 | 64328090 |
Protein urine present | 71.48 | 11.27 | 62 | 59181 | 8894 | 64430595 |
Joint swelling | 71.33 | 11.27 | 56 | 59187 | 215326 | 64224163 |
Hypersensitivity | 70.37 | 11.27 | 47 | 59196 | 196405 | 64243084 |
Gastroenteritis norovirus | 69.95 | 11.27 | 39 | 59204 | 2736 | 64436753 |
Pancreas transplant rejection | 69.87 | 11.27 | 21 | 59222 | 285 | 64439204 |
Depression | 69.58 | 11.27 | 41 | 59202 | 183250 | 64256239 |
Anxiety | 69.26 | 11.27 | 51 | 59192 | 202598 | 64236891 |
Renal artery stenosis | 67.49 | 11.27 | 39 | 59204 | 2930 | 64436559 |
Graft versus host disease in lung | 67.34 | 11.27 | 26 | 59217 | 778 | 64438711 |
Encephalitis viral | 67.05 | 11.27 | 36 | 59207 | 2344 | 64437145 |
Red blood cells urine positive | 66.79 | 11.27 | 45 | 59198 | 4433 | 64435056 |
Scedosporium infection | 65.71 | 11.27 | 29 | 59214 | 1225 | 64438264 |
Lymphopenia | 65.28 | 11.27 | 98 | 59145 | 25559 | 64413930 |
Acanthamoeba infection | 64.20 | 11.27 | 22 | 59221 | 464 | 64439025 |
Malignant neoplasm progression | 63.75 | 11.27 | 13 | 59230 | 112858 | 64326631 |
Malacoplakia gastrointestinal | 62.12 | 11.27 | 17 | 59226 | 161 | 64439328 |
Viraemia | 61.92 | 11.27 | 34 | 59209 | 2315 | 64437174 |
Renal tubular injury | 61.32 | 11.27 | 27 | 59216 | 1134 | 64438355 |
Intentional overdose | 60.93 | 11.27 | 6 | 59237 | 89938 | 64349551 |
Pneumonia cryptococcal | 59.64 | 11.27 | 27 | 59216 | 1212 | 64438277 |
Blood urea increased | 58.59 | 11.27 | 127 | 59116 | 44026 | 64395463 |
Human polyomavirus infection | 58.07 | 11.27 | 25 | 59218 | 994 | 64438495 |
Cryptosporidiosis infection | 58.05 | 11.27 | 22 | 59221 | 625 | 64438864 |
Malaise | 57.51 | 11.27 | 180 | 59063 | 396067 | 64043422 |
Central nervous system lymphoma | 56.57 | 11.27 | 30 | 59213 | 1905 | 64437584 |
Alternaria infection | 56.42 | 11.27 | 21 | 59222 | 567 | 64438922 |
Urinoma | 56.39 | 11.27 | 16 | 59227 | 175 | 64439314 |
Drug interaction | 56.15 | 11.27 | 543 | 58700 | 361540 | 64077949 |
Contraindicated product administered | 55.79 | 11.27 | 15 | 59228 | 107814 | 64331675 |
American trypanosomiasis | 55.61 | 11.27 | 18 | 59225 | 316 | 64439173 |
Ureaplasma infection | 55.24 | 11.27 | 22 | 59221 | 716 | 64438773 |
Pulmonary nocardiosis | 54.64 | 11.27 | 22 | 59221 | 737 | 64438752 |
Candida infection | 54.43 | 11.27 | 101 | 59142 | 31318 | 64408171 |
Escherichia urinary tract infection | 54.26 | 11.27 | 61 | 59182 | 11976 | 64427513 |
Synovitis | 52.77 | 11.27 | 13 | 59230 | 99077 | 64340412 |
Haemolytic uraemic syndrome | 51.97 | 11.27 | 37 | 59206 | 3984 | 64435505 |
Disseminated mucormycosis | 51.90 | 11.27 | 19 | 59224 | 489 | 64439000 |
Mycobacterial infection | 51.82 | 11.27 | 33 | 59210 | 2955 | 64436534 |
Infusion related reaction | 50.46 | 11.27 | 46 | 59197 | 164421 | 64275068 |
Acinetobacter infection | 50.20 | 11.27 | 30 | 59213 | 2399 | 64437090 |
Injection site erythema | 49.91 | 11.27 | 4 | 59239 | 70796 | 64368693 |
Ureteric stenosis | 49.82 | 11.27 | 24 | 59219 | 1242 | 64438247 |
Hydronephrosis | 49.55 | 11.27 | 63 | 59180 | 14062 | 64425427 |
Papilloma viral infection | 49.42 | 11.27 | 25 | 59218 | 1439 | 64438050 |
Dyspnoea | 49.34 | 11.27 | 423 | 58820 | 718251 | 63721238 |
Pain in extremity | 48.82 | 11.27 | 131 | 59112 | 302954 | 64136535 |
Constipation | 48.64 | 11.27 | 85 | 59158 | 229252 | 64210237 |
Pyelonephritis | 48.34 | 11.27 | 69 | 59174 | 17197 | 64422292 |
Graft versus host disease in liver | 48.21 | 11.27 | 25 | 59218 | 1516 | 64437973 |
Acute graft versus host disease | 47.88 | 11.27 | 50 | 59193 | 9034 | 64430455 |
Coronavirus infection | 47.64 | 11.27 | 40 | 59203 | 5490 | 64433999 |
Post transplant distal limb syndrome | 47.47 | 11.27 | 18 | 59225 | 512 | 64438977 |
Toxoplasmosis | 47.45 | 11.27 | 29 | 59214 | 2415 | 64437074 |
Philadelphia positive chronic myeloid leukaemia | 47.42 | 11.27 | 13 | 59230 | 124 | 64439365 |
Immunosuppressant drug level decreased | 47.09 | 11.27 | 26 | 59217 | 1789 | 64437700 |
Renal transplant | 47.07 | 11.27 | 28 | 59215 | 2220 | 64437269 |
Anogenital warts | 46.53 | 11.27 | 20 | 59223 | 792 | 64438697 |
Syncope | 46.13 | 11.27 | 46 | 59197 | 157589 | 64281900 |
Human ehrlichiosis | 45.35 | 11.27 | 16 | 59227 | 369 | 64439120 |
Insomnia | 45.05 | 11.27 | 70 | 59173 | 197766 | 64241723 |
Diarrhoea | 44.64 | 11.27 | 920 | 58323 | 721784 | 63717705 |
Donor specific antibody present | 44.63 | 11.27 | 14 | 59229 | 221 | 64439268 |
Dermatophytosis | 44.52 | 11.27 | 16 | 59227 | 390 | 64439099 |
Meningitis cryptococcal | 44.31 | 11.27 | 30 | 59213 | 2979 | 64436510 |
Angiosarcoma | 43.88 | 11.27 | 16 | 59227 | 407 | 64439082 |
Rheumatoid arthritis | 43.59 | 11.27 | 52 | 59191 | 164242 | 64275247 |
Epstein-Barr virus associated lymphoproliferative disorder | 43.33 | 11.27 | 30 | 59213 | 3089 | 64436400 |
Bacterial pyelonephritis | 43.31 | 11.27 | 17 | 59226 | 532 | 64438957 |
Squamous cell carcinoma of skin | 43.30 | 11.27 | 54 | 59189 | 11822 | 64427667 |
Lung transplant rejection | 42.79 | 11.27 | 22 | 59221 | 1310 | 64438179 |
Alveolar proteinosis | 42.41 | 11.27 | 17 | 59226 | 563 | 64438926 |
Stomatitis | 42.31 | 11.27 | 24 | 59219 | 109581 | 64329908 |
Smooth muscle cell neoplasm | 42.09 | 11.27 | 19 | 59224 | 847 | 64438642 |
Therapeutic product effect decreased | 42.09 | 11.27 | 27 | 59216 | 115324 | 64324165 |
End stage renal disease | 42.04 | 11.27 | 50 | 59193 | 10425 | 64429064 |
Urticaria | 41.95 | 11.27 | 44 | 59199 | 147273 | 64292216 |
Chronic graft versus host disease | 41.34 | 11.27 | 39 | 59204 | 6237 | 64433252 |
Human herpesvirus 8 infection | 41.19 | 11.27 | 20 | 59223 | 1053 | 64438436 |
Contusion | 41.14 | 11.27 | 27 | 59216 | 113938 | 64325551 |
Encephalitis | 40.86 | 11.27 | 54 | 59189 | 12517 | 64426972 |
Cardiac failure congestive | 40.67 | 11.27 | 36 | 59207 | 130544 | 64308945 |
Heart transplant rejection | 40.61 | 11.27 | 21 | 59222 | 1266 | 64438223 |
Myocardial infarction | 40.36 | 11.27 | 56 | 59187 | 165765 | 64273724 |
Decreased appetite | 39.91 | 11.27 | 129 | 59114 | 281160 | 64158329 |
Immune reconstitution inflammatory syndrome | 39.66 | 11.27 | 53 | 59190 | 12417 | 64427072 |
Back pain | 39.62 | 11.27 | 109 | 59134 | 250062 | 64189427 |
Trichophytosis | 39.59 | 11.27 | 14 | 59229 | 325 | 64439164 |
Balance disorder | 39.24 | 11.27 | 14 | 59229 | 83912 | 64355577 |
Urinary fistula | 39.08 | 11.27 | 10 | 59233 | 71 | 64439418 |
Nausea | 39.01 | 11.27 | 499 | 58744 | 785301 | 63654188 |
Asthenia | 39.01 | 11.27 | 232 | 59011 | 427812 | 64011677 |
Urinary tract infection | 38.68 | 11.27 | 353 | 58890 | 231243 | 64208246 |
Squamous cell carcinoma | 38.20 | 11.27 | 55 | 59188 | 13814 | 64425675 |
Erythema | 38.16 | 11.27 | 71 | 59172 | 186999 | 64252490 |
Glomerulonephritis | 37.97 | 11.27 | 27 | 59216 | 2901 | 64436588 |
Intentional product misuse | 37.50 | 11.27 | 10 | 59233 | 72285 | 64367204 |
Gastroenteritis sapovirus | 37.18 | 11.27 | 11 | 59232 | 141 | 64439348 |
Peripheral swelling | 37.09 | 11.27 | 86 | 59157 | 209067 | 64230422 |
Cytomegalovirus nephritis | 37.03 | 11.27 | 11 | 59232 | 143 | 64439346 |
Feeling abnormal | 36.82 | 11.27 | 41 | 59202 | 133561 | 64305928 |
Biopsy lung abnormal | 36.76 | 11.27 | 11 | 59232 | 147 | 64439342 |
Enterobacter infection | 36.61 | 11.27 | 29 | 59214 | 3667 | 64435822 |
Hypogammaglobulinaemia | 36.22 | 11.27 | 46 | 59197 | 10253 | 64429236 |
Musculoskeletal stiffness | 35.99 | 11.27 | 36 | 59207 | 123170 | 64316319 |
Chronic graft versus host disease in liver | 35.83 | 11.27 | 15 | 59228 | 556 | 64438933 |
Hernial eventration | 35.80 | 11.27 | 9 | 59234 | 59 | 64439430 |
Gastrointestinal mucormycosis | 35.35 | 11.27 | 13 | 59230 | 339 | 64439150 |
Nasopharyngitis | 35.26 | 11.27 | 80 | 59163 | 195993 | 64243496 |
Asthma | 35.14 | 11.27 | 22 | 59221 | 95203 | 64344286 |
Oesophageal candidiasis | 35.07 | 11.27 | 40 | 59203 | 7977 | 64431512 |
Pathogen resistance | 34.93 | 11.27 | 50 | 59193 | 12493 | 64426996 |
Suicidal ideation | 34.90 | 11.27 | 9 | 59234 | 66533 | 64372956 |
Hyperhidrosis | 34.80 | 11.27 | 38 | 59205 | 124882 | 64314607 |
Chronic obstructive pulmonary disease | 34.70 | 11.27 | 11 | 59232 | 71037 | 64368452 |
Drug resistance | 34.66 | 11.27 | 90 | 59153 | 35012 | 64404477 |
Histoplasmosis cutaneous | 34.35 | 11.27 | 8 | 59235 | 36 | 64439453 |
Neutrophil count decreased | 34.22 | 11.27 | 14 | 59229 | 77182 | 64362307 |
Bacterial sepsis | 33.97 | 11.27 | 38 | 59205 | 7419 | 64432070 |
Alopecia | 33.69 | 11.27 | 63 | 59180 | 165627 | 64273862 |
Wrong technique in product usage process | 33.68 | 11.27 | 9 | 59234 | 64965 | 64374524 |
Meningoencephalitis amoebic | 33.60 | 11.27 | 10 | 59233 | 131 | 64439358 |
Chronic graft versus host disease in skin | 33.57 | 11.27 | 19 | 59224 | 1372 | 64438117 |
Pneumocystis jirovecii infection | 33.49 | 11.27 | 23 | 59220 | 2338 | 64437151 |
Necrotising oesophagitis | 33.10 | 11.27 | 15 | 59228 | 675 | 64438814 |
Mycobacterium avium complex infection | 32.91 | 11.27 | 28 | 59215 | 3912 | 64435577 |
Cerebral aspergillosis | 32.64 | 11.27 | 20 | 59223 | 1673 | 64437816 |
Chronic kidney disease | 32.50 | 11.27 | 122 | 59121 | 57797 | 64381692 |
Oesophageal ulcer | 32.41 | 11.27 | 34 | 59209 | 6176 | 64433313 |
Herpes simplex hepatitis | 32.39 | 11.27 | 13 | 59230 | 432 | 64439057 |
Wound | 32.11 | 11.27 | 15 | 59228 | 76462 | 64363027 |
Stress | 32.11 | 11.27 | 8 | 59235 | 60526 | 64378963 |
Pyelonephritis acute | 32.10 | 11.27 | 31 | 59212 | 5103 | 64434386 |
Wheezing | 32.03 | 11.27 | 17 | 59226 | 80562 | 64358927 |
Actinic keratosis | 31.94 | 11.27 | 31 | 59212 | 5134 | 64434355 |
Renal cyst haemorrhage | 31.91 | 11.27 | 13 | 59230 | 449 | 64439040 |
Intraductal papillary mucinous neoplasm | 31.91 | 11.27 | 14 | 59229 | 583 | 64438906 |
Lung transplant | 31.90 | 11.27 | 28 | 59215 | 4080 | 64435409 |
Epstein-Barr virus associated lymphoma | 31.69 | 11.27 | 16 | 59227 | 917 | 64438572 |
Hospitalisation | 31.64 | 11.27 | 145 | 59098 | 75062 | 64364427 |
Sepsis | 31.59 | 11.27 | 337 | 58906 | 230004 | 64209485 |
Mycobacterium haemophilum infection | 31.37 | 11.27 | 8 | 59235 | 56 | 64439433 |
Drug reaction with eosinophilia and systemic symptoms | 31.12 | 11.27 | 6 | 59237 | 54211 | 64385278 |
Ventricular remodelling | 30.88 | 11.27 | 9 | 59234 | 109 | 64439380 |
Discomfort | 30.80 | 11.27 | 18 | 59225 | 80860 | 64358629 |
Renal lymphocele | 30.66 | 11.27 | 9 | 59234 | 112 | 64439377 |
Disseminated tuberculosis | 30.65 | 11.27 | 26 | 59217 | 3619 | 64435870 |
Osteoarthritis | 30.59 | 11.27 | 10 | 59233 | 63326 | 64376163 |
Disseminated varicella zoster vaccine virus infection | 30.51 | 11.27 | 9 | 59234 | 114 | 64439375 |
Injury | 30.49 | 11.27 | 7 | 59236 | 55985 | 64383504 |
Disease recurrence | 30.30 | 11.27 | 80 | 59163 | 31430 | 64408059 |
Urinary tract infection bacterial | 30.29 | 11.27 | 30 | 59213 | 5091 | 64434398 |
Muscle spasms | 30.12 | 11.27 | 52 | 59191 | 140971 | 64298518 |
Malacoplakia vesicae | 30.00 | 11.27 | 8 | 59235 | 68 | 64439421 |
Heart rate decreased | 29.75 | 11.27 | 7 | 59236 | 55060 | 64384429 |
Oesophageal stenosis | 29.51 | 11.27 | 26 | 59217 | 3808 | 64435681 |
Chromoblastomycosis | 29.50 | 11.27 | 8 | 59235 | 73 | 64439416 |
Injection site reaction | 29.39 | 11.27 | 4 | 59239 | 46660 | 64392829 |
Hypoaesthesia | 29.07 | 11.27 | 52 | 59191 | 139056 | 64300433 |
Perinephric collection | 29.04 | 11.27 | 11 | 59232 | 312 | 64439177 |
Hypotension | 28.91 | 11.27 | 218 | 59025 | 380756 | 64058733 |
Pneumopericardium | 28.81 | 11.27 | 9 | 59234 | 140 | 64439349 |
Vena cava injury | 28.79 | 11.27 | 10 | 59233 | 220 | 64439269 |
Obliterative bronchiolitis | 28.76 | 11.27 | 22 | 59221 | 2643 | 64436846 |
Pyrexia | 28.66 | 11.27 | 693 | 58550 | 557951 | 63881538 |
Staphylococcal infection | 28.64 | 11.27 | 107 | 59136 | 50571 | 64388918 |
Somnolence | 28.44 | 11.27 | 94 | 59149 | 203551 | 64235938 |
Fungal skin infection | 28.44 | 11.27 | 29 | 59214 | 5096 | 64434393 |
Biloma | 28.35 | 11.27 | 9 | 59234 | 148 | 64439341 |
Swelling | 28.29 | 11.27 | 66 | 59177 | 160152 | 64279337 |
Microsporidia infection | 28.25 | 11.27 | 14 | 59229 | 771 | 64438718 |
Respiratory arrest | 28.11 | 11.27 | 7 | 59236 | 52978 | 64386511 |
Biliary anastomosis complication | 28.02 | 11.27 | 9 | 59234 | 154 | 64439335 |
SARS-CoV-2 antibody test positive | 28.01 | 11.27 | 10 | 59233 | 239 | 64439250 |
Escherichia pyelonephritis | 27.90 | 11.27 | 12 | 59231 | 476 | 64439013 |
Cystitis viral | 27.88 | 11.27 | 13 | 59230 | 625 | 64438864 |
Neuroendocrine carcinoma of the skin | 27.70 | 11.27 | 15 | 59228 | 993 | 64438496 |
Large intestinal ulcer | 27.51 | 11.27 | 26 | 59217 | 4167 | 64435322 |
Gastroenteritis cryptosporidial | 27.40 | 11.27 | 10 | 59233 | 255 | 64439234 |
Pancytopenia | 27.33 | 11.27 | 225 | 59018 | 143084 | 64296405 |
Cardio-respiratory arrest | 27.32 | 11.27 | 30 | 59213 | 98363 | 64341126 |
Electrocardiogram QT prolonged | 27.11 | 11.27 | 20 | 59223 | 79428 | 64360061 |
Prophylaxis against transplant rejection | 26.97 | 11.27 | 7 | 59236 | 53 | 64439436 |
Atypical haemolytic uraemic syndrome | 26.87 | 11.27 | 13 | 59230 | 679 | 64438810 |
Weight increased | 26.79 | 11.27 | 103 | 59140 | 213245 | 64226244 |
Suicide attempt | 26.76 | 11.27 | 16 | 59227 | 70991 | 64368498 |
Chemical peritonitis | 26.73 | 11.27 | 10 | 59233 | 274 | 64439215 |
Chronic hepatitis C | 26.67 | 11.27 | 12 | 59231 | 531 | 64438958 |
Paraesthesia | 26.60 | 11.27 | 52 | 59191 | 134470 | 64305019 |
Isosporiasis | 26.45 | 11.27 | 8 | 59235 | 111 | 64439378 |
Cerebral toxoplasmosis | 26.40 | 11.27 | 18 | 59225 | 1808 | 64437681 |
Bacillary angiomatosis | 26.34 | 11.27 | 9 | 59234 | 188 | 64439301 |
Cytomegalovirus syndrome | 26.26 | 11.27 | 10 | 59233 | 288 | 64439201 |
Necrotising herpetic retinopathy | 26.07 | 11.27 | 8 | 59235 | 117 | 64439372 |
Mouth ulceration | 25.91 | 11.27 | 77 | 59166 | 32367 | 64407122 |
Bacterial infection | 25.70 | 11.27 | 65 | 59178 | 24885 | 64414604 |
Confusional state | 25.66 | 11.27 | 138 | 59105 | 261006 | 64178483 |
Complications of transplanted heart | 25.66 | 11.27 | 10 | 59233 | 307 | 64439182 |
Neuropathy peripheral | 25.41 | 11.27 | 43 | 59200 | 117482 | 64322007 |
Cytomegalovirus hepatitis | 25.39 | 11.27 | 12 | 59231 | 595 | 64438894 |
Superinfection bacterial | 25.38 | 11.27 | 15 | 59228 | 1175 | 64438314 |
Pneumonia escherichia | 25.30 | 11.27 | 13 | 59230 | 773 | 64438716 |
Headache | 25.17 | 11.27 | 339 | 58904 | 529128 | 63910361 |
Gait disturbance | 25.06 | 11.27 | 78 | 59165 | 172077 | 64267412 |
Encephalitis cytomegalovirus | 24.99 | 11.27 | 14 | 59229 | 991 | 64438498 |
Cutaneous malacoplakia | 24.97 | 11.27 | 7 | 59236 | 73 | 64439416 |
Rectal prolapse | 24.92 | 11.27 | 17 | 59226 | 1709 | 64437780 |
Pulmonary mucormycosis | 24.90 | 11.27 | 13 | 59230 | 799 | 64438690 |
Haemoglobin decreased | 24.71 | 11.27 | 281 | 58962 | 194782 | 64244707 |
Meningitis bacterial | 24.54 | 11.27 | 19 | 59224 | 2324 | 64437165 |
Acute myocardial infarction | 24.51 | 11.27 | 17 | 59226 | 69701 | 64369788 |
Injection site pruritus | 24.40 | 11.27 | 3 | 59240 | 37823 | 64401666 |
Fungal infection | 24.30 | 11.27 | 78 | 59165 | 34173 | 64405316 |
Metabolic acidosis | 24.28 | 11.27 | 129 | 59114 | 70829 | 64368660 |
Sinusitis | 24.28 | 11.27 | 62 | 59181 | 145866 | 64293623 |
Nephropathy | 24.19 | 11.27 | 34 | 59209 | 8352 | 64431137 |
Flushing | 24.10 | 11.27 | 22 | 59221 | 78626 | 64360863 |
Pneumonia pseudomonal | 24.09 | 11.27 | 26 | 59217 | 4877 | 64434612 |
Lupus nephritis | 23.97 | 11.27 | 19 | 59224 | 2405 | 64437084 |
Passenger lymphocyte syndrome | 23.85 | 11.27 | 7 | 59236 | 87 | 64439402 |
Mycobacterium chelonae infection | 23.85 | 11.27 | 18 | 59225 | 2119 | 64437370 |
Herpes simplex oesophagitis | 23.84 | 11.27 | 9 | 59234 | 253 | 64439236 |
Product dose omission issue | 23.82 | 11.27 | 95 | 59148 | 194652 | 64244837 |
Cat scratch disease | 23.77 | 11.27 | 9 | 59234 | 255 | 64439234 |
Nasal cavity cancer | 23.69 | 11.27 | 8 | 59235 | 161 | 64439328 |
Coccidioidomycosis | 23.65 | 11.27 | 14 | 59229 | 1100 | 64438389 |
Periostitis | 23.65 | 11.27 | 11 | 59232 | 526 | 64438963 |
Inappropriate schedule of product administration | 23.63 | 11.27 | 30 | 59213 | 92256 | 64347233 |
Aortic pseudoaneurysm | 23.52 | 11.27 | 6 | 59237 | 42 | 64439447 |
Urosepsis | 23.21 | 11.27 | 58 | 59185 | 22036 | 64417453 |
Loss of consciousness | 23.20 | 11.27 | 65 | 59178 | 148300 | 64291189 |
Blood pressure decreased | 23.15 | 11.27 | 27 | 59216 | 86172 | 64353317 |
Infective aortitis | 23.05 | 11.27 | 6 | 59237 | 46 | 64439443 |
Mobility decreased | 22.93 | 11.27 | 27 | 59216 | 85813 | 64353676 |
Anti-erythropoietin antibody negative | 22.86 | 11.27 | 9 | 59234 | 284 | 64439205 |
Postoperative wound infection | 22.83 | 11.27 | 37 | 59206 | 10299 | 64429190 |
Human herpesvirus 6 encephalitis | 22.80 | 11.27 | 10 | 59233 | 416 | 64439073 |
Epidermodysplasia verruciformis | 22.74 | 11.27 | 8 | 59235 | 183 | 64439306 |
Hyperkalaemia | 22.73 | 11.27 | 165 | 59078 | 100964 | 64338525 |
Corynebacterium infection | 22.70 | 11.27 | 13 | 59230 | 960 | 64438529 |
Fibromyalgia | 22.65 | 11.27 | 3 | 59240 | 35728 | 64403761 |
Loss of personal independence in daily activities | 22.52 | 11.27 | 20 | 59223 | 72434 | 64367055 |
Renal tubular acidosis | 22.52 | 11.27 | 20 | 59223 | 2959 | 64436530 |
Liver abscess | 22.51 | 11.27 | 26 | 59217 | 5254 | 64434235 |
Chest pain | 22.47 | 11.27 | 126 | 59117 | 235854 | 64203635 |
Acarodermatitis | 22.35 | 11.27 | 14 | 59229 | 1218 | 64438271 |
Systemic candida | 22.32 | 11.27 | 26 | 59217 | 5303 | 64434186 |
Cytomegalovirus oesophagitis | 22.31 | 11.27 | 11 | 59232 | 599 | 64438890 |
Coronary artery disease | 22.24 | 11.27 | 14 | 59229 | 60419 | 64379070 |
Hypoglycaemia | 22.22 | 11.27 | 30 | 59213 | 89862 | 64349627 |
Metastatic squamous cell carcinoma | 22.19 | 11.27 | 10 | 59233 | 444 | 64439045 |
Cytomegalovirus gastrointestinal infection | 22.15 | 11.27 | 10 | 59233 | 446 | 64439043 |
Catatonia | 22.14 | 11.27 | 31 | 59212 | 7589 | 64431900 |
Blister | 22.14 | 11.27 | 25 | 59218 | 80942 | 64358547 |
Hyperuricaemia | 21.86 | 11.27 | 36 | 59207 | 10155 | 64429334 |
Postoperative thoracic procedure complication | 21.81 | 11.27 | 6 | 59237 | 58 | 64439431 |
Irritable bowel syndrome | 21.73 | 11.27 | 4 | 59239 | 37365 | 64402124 |
Acute graft versus host disease in skin | 21.59 | 11.27 | 29 | 59214 | 6826 | 64432663 |
Toxic epidermal necrolysis | 21.57 | 11.27 | 4 | 59239 | 37162 | 64402327 |
Drug level fluctuating | 21.35 | 11.27 | 11 | 59232 | 658 | 64438831 |
Leishmaniasis | 21.34 | 11.27 | 9 | 59234 | 340 | 64439149 |
Spindle cell sarcoma | 21.32 | 11.27 | 8 | 59235 | 221 | 64439268 |
Necrotising fasciitis fungal | 21.20 | 11.27 | 5 | 59238 | 24 | 64439465 |
New onset diabetes after transplantation | 21.11 | 11.27 | 7 | 59236 | 133 | 64439356 |
Acute graft versus host disease in intestine | 21.09 | 11.27 | 21 | 59222 | 3588 | 64435901 |
Chronic kidney disease-mineral and bone disorder | 21.06 | 11.27 | 10 | 59233 | 501 | 64438988 |
Pericarditis | 20.99 | 11.27 | 16 | 59227 | 62500 | 64376989 |
Optic discs blurred | 20.95 | 11.27 | 6 | 59237 | 68 | 64439421 |
Injection site bruising | 20.93 | 11.27 | 4 | 59239 | 36369 | 64403120 |
Diabetic macroangiopathy | 20.77 | 11.27 | 7 | 59236 | 140 | 64439349 |
Glomerulonephritis proliferative | 20.71 | 11.27 | 9 | 59234 | 366 | 64439123 |
Cytomegalovirus infection reactivation | 20.71 | 11.27 | 26 | 59217 | 5730 | 64433759 |
Necrotising fasciitis | 20.68 | 11.27 | 25 | 59218 | 5301 | 64434188 |
Emotional distress | 20.66 | 11.27 | 4 | 59239 | 36034 | 64403455 |
Drug dependence | 20.64 | 11.27 | 3 | 59240 | 33309 | 64406180 |
Hyperparathyroidism secondary | 20.37 | 11.27 | 17 | 59226 | 2313 | 64437176 |
Lymphadenitis fungal | 20.32 | 11.27 | 4 | 59239 | 6 | 64439483 |
Depressed level of consciousness | 20.31 | 11.27 | 27 | 59216 | 81409 | 64358080 |
Epistaxis | 20.21 | 11.27 | 37 | 59206 | 98094 | 64341395 |
Meningoencephalitis viral | 20.18 | 11.27 | 9 | 59234 | 390 | 64439099 |
Visceral leishmaniasis | 20.13 | 11.27 | 12 | 59231 | 955 | 64438534 |
Dysgeusia | 20.10 | 11.27 | 9 | 59234 | 47038 | 64392451 |
International normalised ratio increased | 19.99 | 11.27 | 26 | 59217 | 79141 | 64360348 |
Complications of transplanted lung | 19.90 | 11.27 | 9 | 59234 | 403 | 64439086 |
Renal graft infection | 19.88 | 11.27 | 9 | 59234 | 404 | 64439085 |
Eccrine squamous syringometaplasia | 19.86 | 11.27 | 5 | 59238 | 33 | 64439456 |
Hepatic fibrosis | 19.85 | 11.27 | 25 | 59218 | 5527 | 64433962 |
Disseminated varicella zoster virus infection | 19.81 | 11.27 | 8 | 59235 | 270 | 64439219 |
Psoriasis | 19.75 | 11.27 | 22 | 59221 | 71681 | 64367808 |
Cytomegalovirus test positive | 19.73 | 11.27 | 24 | 59219 | 5120 | 64434369 |
Ureteral necrosis | 19.66 | 11.27 | 6 | 59237 | 86 | 64439403 |
Parvovirus infection | 19.63 | 11.27 | 10 | 59233 | 584 | 64438905 |
Colitis | 19.62 | 11.27 | 106 | 59137 | 58568 | 64380921 |
Anorectal varices | 19.60 | 11.27 | 5 | 59238 | 35 | 64439454 |
Mycobacterium abscessus infection | 19.60 | 11.27 | 12 | 59231 | 1002 | 64438487 |
Central nervous system lupus | 19.49 | 11.27 | 8 | 59235 | 282 | 64439207 |
Serotonin syndrome | 19.33 | 11.27 | 6 | 59237 | 39276 | 64400213 |
Lower respiratory tract infection | 19.20 | 11.27 | 36 | 59207 | 94578 | 64344911 |
Pneumonia klebsiella | 19.13 | 11.27 | 21 | 59222 | 4016 | 64435473 |
Exposure during pregnancy | 19.12 | 11.27 | 26 | 59217 | 77649 | 64361840 |
Nosocomial infection | 19.12 | 11.27 | 17 | 59226 | 2520 | 64436969 |
Febrile neutropenia | 19.08 | 11.27 | 98 | 59145 | 187559 | 64251930 |
Tuberculosis | 19.03 | 11.27 | 39 | 59204 | 12999 | 64426490 |
Renal vein thrombosis | 19.01 | 11.27 | 9 | 59234 | 448 | 64439041 |
Cytomegalovirus chorioretinitis | 18.98 | 11.27 | 23 | 59220 | 4889 | 64434600 |
Histology abnormal | 18.90 | 11.27 | 8 | 59235 | 305 | 64439184 |
Liver transplant | 18.89 | 11.27 | 21 | 59222 | 4071 | 64435418 |
Propionibacterium infection | 18.87 | 11.27 | 8 | 59235 | 306 | 64439183 |
Renal failure | 18.80 | 11.27 | 252 | 58991 | 181436 | 64258053 |
Acid base balance abnormal | 18.80 | 11.27 | 8 | 59235 | 309 | 64439180 |
Disseminated mycobacterium avium complex infection | 18.77 | 11.27 | 6 | 59237 | 101 | 64439388 |
Bilirubin conjugated increased | 18.77 | 11.27 | 23 | 59220 | 4945 | 64434544 |
Arthritis | 18.73 | 11.27 | 30 | 59213 | 83784 | 64355705 |
Functional gastrointestinal disorder | 18.73 | 11.27 | 21 | 59222 | 4110 | 64435379 |
Drug level decreased | 18.70 | 11.27 | 36 | 59207 | 11467 | 64428022 |
Abdominal discomfort | 18.65 | 11.27 | 95 | 59148 | 182227 | 64257262 |
Hepatitis C | 18.56 | 11.27 | 35 | 59208 | 10980 | 64428509 |
Listeriosis | 18.54 | 11.27 | 15 | 59228 | 1955 | 64437534 |
Fungaemia | 18.47 | 11.27 | 20 | 59223 | 3765 | 64435724 |
Dermatitis papillaris capillitii | 18.44 | 11.27 | 4 | 59239 | 12 | 64439477 |
Argentine haemorrhagic fever | 18.44 | 11.27 | 4 | 59239 | 12 | 64439477 |
Transmission of an infectious agent via transplant | 18.44 | 11.27 | 4 | 59239 | 12 | 64439477 |
Opportunistic infection | 18.41 | 11.27 | 17 | 59226 | 2645 | 64436844 |
Vaccination failure | 18.40 | 11.27 | 11 | 59232 | 880 | 64438609 |
Blood creatine phosphokinase increased | 18.40 | 11.27 | 16 | 59227 | 58542 | 64380947 |
Anti-GAD antibody positive | 18.40 | 11.27 | 5 | 59238 | 46 | 64439443 |
Bordetella infection | 18.40 | 11.27 | 6 | 59237 | 108 | 64439381 |
Acute graft versus host disease in liver | 18.37 | 11.27 | 14 | 59229 | 1673 | 64437816 |
Hallucination | 18.28 | 11.27 | 24 | 59219 | 72764 | 64366725 |
Pyelonephritis fungal | 18.19 | 11.27 | 6 | 59237 | 112 | 64439377 |
Polyomavirus test positive | 18.17 | 11.27 | 7 | 59236 | 208 | 64439281 |
Organising pneumonia | 18.11 | 11.27 | 31 | 59212 | 9024 | 64430465 |
IgA nephropathy | 18.08 | 11.27 | 13 | 59230 | 1421 | 64438068 |
Transient ischaemic attack | 18.04 | 11.27 | 9 | 59234 | 44173 | 64395316 |
Perinephric abscess | 18.02 | 11.27 | 7 | 59236 | 213 | 64439276 |
Bronchiectasis | 17.99 | 11.27 | 40 | 59203 | 14100 | 64425389 |
Vesicoureteral reflux surgery | 17.98 | 11.27 | 3 | 59240 | 0 | 64439489 |
Gingival hypertrophy | 17.96 | 11.27 | 17 | 59226 | 2730 | 64436759 |
Respiratory distress | 17.81 | 11.27 | 95 | 59148 | 52236 | 64387253 |
Phaeohyphomycotic brain abscess | 17.76 | 11.27 | 5 | 59238 | 53 | 64439436 |
Lymphorrhoea | 17.71 | 11.27 | 6 | 59237 | 122 | 64439367 |
Serratia infection | 17.46 | 11.27 | 13 | 59230 | 1500 | 64437989 |
Emphysematous pyelonephritis | 17.46 | 11.27 | 7 | 59236 | 232 | 64439257 |
Acute pulmonary histoplasmosis | 17.37 | 11.27 | 7 | 59236 | 235 | 64439254 |
Neurotoxicity | 17.30 | 11.27 | 60 | 59183 | 27344 | 64412145 |
Transplantation complication | 17.26 | 11.27 | 7 | 59236 | 239 | 64439250 |
Neoplasm progression | 17.25 | 11.27 | 8 | 59235 | 40956 | 64398533 |
Dry mouth | 17.24 | 11.27 | 18 | 59225 | 60400 | 64379089 |
Herpes simplex | 17.16 | 11.27 | 33 | 59210 | 10503 | 64428986 |
Bacteraemia | 17.06 | 11.27 | 59 | 59184 | 26852 | 64412637 |
Orthostatic hypotension | 16.96 | 11.27 | 11 | 59232 | 46727 | 64392762 |
Haemoglobinaemia | 16.86 | 11.27 | 7 | 59236 | 254 | 64439235 |
Drug withdrawal syndrome | 16.86 | 11.27 | 4 | 59239 | 31287 | 64408202 |
Haemolytic anaemia | 16.72 | 11.27 | 42 | 59201 | 16011 | 64423478 |
Delusion of grandeur | 16.69 | 11.27 | 9 | 59234 | 591 | 64438898 |
Plasmapheresis | 16.69 | 11.27 | 9 | 59234 | 591 | 64438898 |
Hot flush | 16.62 | 11.27 | 11 | 59232 | 46224 | 64393265 |
Aggression | 16.62 | 11.27 | 11 | 59232 | 46221 | 64393268 |
Rash pruritic | 16.50 | 11.27 | 17 | 59226 | 57387 | 64382102 |
Mucinous adenocarcinoma of appendix | 16.36 | 11.27 | 4 | 59239 | 23 | 64439466 |
Agranulocytosis | 16.29 | 11.27 | 74 | 59169 | 38155 | 64401334 |
Pneumatosis intestinalis | 16.29 | 11.27 | 22 | 59221 | 5207 | 64434282 |
Myopathy toxic | 16.16 | 11.27 | 10 | 59233 | 851 | 64438638 |
Hepatic enzyme increased | 16.13 | 11.27 | 63 | 59180 | 129880 | 64309609 |
Hyperammonaemia | 16.11 | 11.27 | 31 | 59212 | 9873 | 64429616 |
Endocarditis | 16.05 | 11.27 | 30 | 59213 | 9348 | 64430141 |
Peritonitis | 15.98 | 11.27 | 55 | 59188 | 24968 | 64414521 |
Pneumonia fungal | 15.95 | 11.27 | 29 | 59214 | 8848 | 64430641 |
Blood pressure increased | 15.95 | 11.27 | 93 | 59150 | 172459 | 64267030 |
Agitation | 15.92 | 11.27 | 36 | 59207 | 88331 | 64351158 |
Oral pain | 15.87 | 11.27 | 3 | 59240 | 27490 | 64411999 |
Systemic bacterial infection | 15.81 | 11.27 | 4 | 59239 | 27 | 64439462 |
Neck pain | 15.75 | 11.27 | 20 | 59223 | 61513 | 64377976 |
Hypertriglyceridaemia | 15.75 | 11.27 | 33 | 59210 | 11172 | 64428317 |
Incisional hernia | 15.74 | 11.27 | 14 | 59229 | 2076 | 64437413 |
Platelet count decreased | 15.71 | 11.27 | 90 | 59153 | 167621 | 64271868 |
Pancreatitis necrotising | 15.70 | 11.27 | 17 | 59226 | 3200 | 64436289 |
Enterovirus infection | 15.66 | 11.27 | 12 | 59231 | 1445 | 64438044 |
Neutropenia | 15.66 | 11.27 | 308 | 58935 | 239316 | 64200173 |
Infective tenosynovitis | 15.64 | 11.27 | 7 | 59236 | 306 | 64439183 |
Cytomegalovirus mucocutaneous ulcer | 15.60 | 11.27 | 5 | 59238 | 85 | 64439404 |
B-cell lymphoma | 15.56 | 11.27 | 22 | 59221 | 5435 | 64434054 |
Knee arthroplasty | 15.47 | 11.27 | 3 | 59240 | 26996 | 64412493 |
Femur fracture | 15.44 | 11.27 | 6 | 59237 | 34129 | 64405360 |
Normocytic anaemia | 15.35 | 11.27 | 17 | 59226 | 3282 | 64436207 |
BK polyomavirus test positive | 15.28 | 11.27 | 5 | 59238 | 91 | 64439398 |
Tuberculosis gastrointestinal | 15.26 | 11.27 | 8 | 59235 | 496 | 64438993 |
Hemianopia heteronymous | 15.23 | 11.27 | 5 | 59238 | 92 | 64439397 |
Lymphoproliferative disorder | 15.18 | 11.27 | 21 | 59222 | 5082 | 64434407 |
Legionella infection | 15.09 | 11.27 | 9 | 59234 | 717 | 64438772 |
Tularaemia | 15.08 | 11.27 | 5 | 59238 | 95 | 64439394 |
Bacterial colitis | 15.08 | 11.27 | 5 | 59238 | 95 | 64439394 |
Balamuthia infection | 15.00 | 11.27 | 4 | 59239 | 34 | 64439455 |
Complications of transplant surgery | 14.94 | 11.27 | 9 | 59234 | 730 | 64438759 |
Ejection fraction decreased | 14.83 | 11.27 | 4 | 59239 | 28703 | 64410786 |
Pulmonary mass | 14.66 | 11.27 | 52 | 59191 | 23964 | 64415525 |
Acinetobacter bacteraemia | 14.57 | 11.27 | 6 | 59237 | 213 | 64439276 |
Memory impairment | 14.56 | 11.27 | 36 | 59207 | 85646 | 64353843 |
Stenotrophomonas infection | 14.55 | 11.27 | 16 | 59227 | 3064 | 64436425 |
Tuberculoma of central nervous system | 14.55 | 11.27 | 8 | 59235 | 546 | 64438943 |
Cardiac murmur functional | 14.51 | 11.27 | 4 | 59239 | 39 | 64439450 |
Swollen tongue | 14.45 | 11.27 | 7 | 59236 | 34947 | 64404542 |
Secondary immunodeficiency | 14.37 | 11.27 | 15 | 59228 | 2709 | 64436780 |
Swelling face | 14.36 | 11.27 | 20 | 59223 | 59146 | 64380343 |
Fungal sepsis | 14.30 | 11.27 | 12 | 59231 | 1646 | 64437843 |
Maternal exposure during pregnancy | 14.26 | 11.27 | 43 | 59200 | 95841 | 64343648 |
Pallor | 14.25 | 11.27 | 9 | 59234 | 38772 | 64400717 |
Scopulariopsis infection | 14.23 | 11.27 | 5 | 59238 | 114 | 64439375 |
Angiocentric lymphoma | 14.21 | 11.27 | 9 | 59234 | 798 | 64438691 |
Mediastinitis | 14.19 | 11.27 | 9 | 59234 | 800 | 64438689 |
Hypoalbuminaemia | 14.16 | 11.27 | 42 | 59201 | 17632 | 64421857 |
Azotaemia | 14.11 | 11.27 | 25 | 59218 | 7477 | 64432012 |
Sebaceous carcinoma | 14.10 | 11.27 | 5 | 59238 | 117 | 64439372 |
Cardiac failure | 14.10 | 11.27 | 68 | 59175 | 132305 | 64307184 |
Endocarditis viral | 14.09 | 11.27 | 3 | 59240 | 8 | 64439481 |
Folliculitis | 14.08 | 11.27 | 5 | 59238 | 30072 | 64409417 |
Palpitations | 14.05 | 11.27 | 49 | 59194 | 104439 | 64335050 |
Anaphylactic reaction | 14.04 | 11.27 | 26 | 59217 | 68638 | 64370851 |
Oliguria | 14.01 | 11.27 | 37 | 59206 | 14539 | 64424950 |
Sinus tachycardia | 14.00 | 11.27 | 6 | 59237 | 32182 | 64407307 |
Helicobacter infection | 13.96 | 11.27 | 9 | 59234 | 38353 | 64401136 |
Mycobacterium marinum infection | 13.95 | 11.27 | 7 | 59236 | 396 | 64439093 |
Capillaritis | 13.95 | 11.27 | 6 | 59237 | 238 | 64439251 |
Cerebrovascular accident | 13.89 | 11.27 | 72 | 59171 | 137511 | 64301978 |
Full blood count abnormal | 13.84 | 11.27 | 5 | 59238 | 29752 | 64409737 |
Conjunctival neoplasm | 13.83 | 11.27 | 3 | 59240 | 9 | 64439480 |
Drug eruption | 13.81 | 11.27 | 8 | 59235 | 36128 | 64403361 |
Venous stenosis | 13.81 | 11.27 | 6 | 59237 | 244 | 64439245 |
Lip swelling | 13.80 | 11.27 | 6 | 59237 | 31901 | 64407588 |
Feeling hot | 13.72 | 11.27 | 13 | 59230 | 45650 | 64393839 |
Bacteroides bacteraemia | 13.68 | 11.27 | 4 | 59239 | 49 | 64439440 |
Graft thrombosis | 13.61 | 11.27 | 7 | 59236 | 417 | 64439072 |
Gastrointestinal mucosa hyperaemia | 13.61 | 11.27 | 7 | 59236 | 417 | 64439072 |
Disseminated cytomegaloviral infection | 13.60 | 11.27 | 7 | 59236 | 418 | 64439071 |
Abdominal wall haemorrhage | 13.60 | 11.27 | 7 | 59236 | 418 | 64439071 |
Hepatic echinococciasis | 13.59 | 11.27 | 3 | 59240 | 10 | 64439479 |
CD8 lymphocytes decreased | 13.54 | 11.27 | 6 | 59237 | 256 | 64439233 |
Cytomegalovirus gastroenteritis | 13.54 | 11.27 | 7 | 59236 | 422 | 64439067 |
Bile duct stenosis | 13.53 | 11.27 | 12 | 59231 | 1772 | 64437717 |
Haemodynamic instability | 13.47 | 11.27 | 37 | 59206 | 14875 | 64424614 |
Leiomyosarcoma | 13.45 | 11.27 | 6 | 59237 | 260 | 64439229 |
Hyperamylasaemia | 13.40 | 11.27 | 9 | 59234 | 882 | 64438607 |
Meningitis histoplasma | 13.37 | 11.27 | 3 | 59240 | 11 | 64439478 |
Hypervolaemia | 13.37 | 11.27 | 70 | 59173 | 38215 | 64401274 |
Graft complication | 13.29 | 11.27 | 8 | 59235 | 648 | 64438841 |
Urinary tract candidiasis | 13.24 | 11.27 | 8 | 59235 | 653 | 64438836 |
Blood albumin decreased | 13.18 | 11.27 | 46 | 59197 | 21027 | 64418462 |
Upper gastrointestinal haemorrhage | 13.18 | 11.27 | 8 | 59235 | 35212 | 64404277 |
Palmar-plantar erythrodysaesthesia syndrome | 13.14 | 11.27 | 5 | 59238 | 28814 | 64410675 |
Herpes oesophagitis | 13.14 | 11.27 | 6 | 59237 | 275 | 64439214 |
Mycoplasma infection | 13.14 | 11.27 | 8 | 59235 | 662 | 64438827 |
Aspartate aminotransferase increased | 13.07 | 11.27 | 61 | 59182 | 119727 | 64319762 |
Post procedural urine leak | 13.06 | 11.27 | 5 | 59238 | 146 | 64439343 |
Medication error | 13.04 | 11.27 | 16 | 59227 | 49950 | 64389539 |
Urine output decreased | 13.04 | 11.27 | 39 | 59204 | 16453 | 64423036 |
Joint tuberculosis | 13.03 | 11.27 | 5 | 59238 | 147 | 64439342 |
Large intestine infection | 13.03 | 11.27 | 14 | 59229 | 2614 | 64436875 |
Accidental exposure to product | 13.02 | 11.27 | 4 | 59239 | 26360 | 64413129 |
Klebsiella sepsis | 13.01 | 11.27 | 14 | 59229 | 2618 | 64436871 |
Purulent pericarditis | 13.00 | 11.27 | 4 | 59239 | 59 | 64439430 |
Cognitive disorder | 13.00 | 11.27 | 19 | 59224 | 55068 | 64384421 |
Adenoviral hepatitis | 12.96 | 11.27 | 7 | 59236 | 461 | 64439028 |
Genital herpes | 12.91 | 11.27 | 12 | 59231 | 1883 | 64437606 |
Myeloma cast nephropathy | 12.91 | 11.27 | 5 | 59238 | 151 | 64439338 |
Wound complication | 12.89 | 11.27 | 17 | 59226 | 3931 | 64435558 |
Steroid diabetes | 12.86 | 11.27 | 14 | 59229 | 2652 | 64436837 |
Pancreas transplant | 12.82 | 11.27 | 4 | 59239 | 62 | 64439427 |
Glomerulosclerosis | 12.75 | 11.27 | 9 | 59234 | 956 | 64438533 |
Dry skin | 12.72 | 11.27 | 17 | 59226 | 51144 | 64388345 |
Pneumoperitoneum | 12.67 | 11.27 | 14 | 59229 | 2697 | 64436792 |
Graft versus host disease in eye | 12.67 | 11.27 | 6 | 59237 | 299 | 64439190 |
Hepatic cyst infection | 12.66 | 11.27 | 5 | 59238 | 159 | 64439330 |
Small intestine gangrene | 12.62 | 11.27 | 3 | 59240 | 15 | 64439474 |
Intra-abdominal haemorrhage | 12.62 | 11.27 | 17 | 59226 | 4014 | 64435475 |
Orf | 12.59 | 11.27 | 4 | 59239 | 66 | 64439423 |
Narrow anterior chamber angle | 12.43 | 11.27 | 5 | 59238 | 167 | 64439322 |
Orbital apex syndrome | 12.42 | 11.27 | 4 | 59239 | 69 | 64439420 |
Obstructive airways disorder | 12.42 | 11.27 | 3 | 59240 | 23182 | 64416307 |
Encephalitis fungal | 12.40 | 11.27 | 5 | 59238 | 168 | 64439321 |
Pemphigus | 12.40 | 11.27 | 23 | 59220 | 60678 | 64378811 |
Splenorenal shunt | 12.31 | 11.27 | 3 | 59240 | 17 | 64439472 |
Mesangioproliferative glomerulonephritis | 12.26 | 11.27 | 4 | 59239 | 72 | 64439417 |
Brain compression | 12.26 | 11.27 | 7 | 59236 | 514 | 64438975 |
Eczema | 12.21 | 11.27 | 6 | 59237 | 29714 | 64409775 |
Rhinovirus infection | 12.21 | 11.27 | 21 | 59222 | 6135 | 64433354 |
Abdominal wall abscess | 12.17 | 11.27 | 9 | 59234 | 1027 | 64438462 |
Urinary tract infection viral | 12.16 | 11.27 | 4 | 59239 | 74 | 64439415 |
Intestinal ulcer perforation | 12.16 | 11.27 | 3 | 59240 | 18 | 64439471 |
Anorexia nervosa | 12.13 | 11.27 | 5 | 59238 | 178 | 64439311 |
Rectal haemorrhage | 12.12 | 11.27 | 24 | 59219 | 61793 | 64377696 |
Nephrotic syndrome | 12.10 | 11.27 | 27 | 59216 | 9540 | 64429949 |
Hyperparathyroidism | 12.09 | 11.27 | 14 | 59229 | 2838 | 64436651 |
Pneumonia adenoviral | 12.08 | 11.27 | 5 | 59238 | 180 | 64439309 |
Pneumonia legionella | 12.07 | 11.27 | 13 | 59230 | 2433 | 64437056 |
Influenza like illness | 12.06 | 11.27 | 24 | 59219 | 61678 | 64377811 |
Carotid arteriosclerosis | 11.97 | 11.27 | 12 | 59231 | 2067 | 64437422 |
Paracoccidioides infection | 11.97 | 11.27 | 4 | 59239 | 78 | 64439411 |
Gene mutation | 11.95 | 11.27 | 12 | 59231 | 2070 | 64437419 |
Granulomatous dermatitis | 11.95 | 11.27 | 6 | 59237 | 340 | 64439149 |
Full blood count decreased | 11.94 | 11.27 | 3 | 59240 | 22579 | 64416910 |
Thyroid gland abscess | 11.92 | 11.27 | 4 | 59239 | 79 | 64439410 |
Alpha haemolytic streptococcal infection | 11.90 | 11.27 | 11 | 59232 | 1714 | 64437775 |
Retinal artery occlusion | 11.88 | 11.27 | 14 | 59229 | 2889 | 64436600 |
Sleep disorder | 11.87 | 11.27 | 23 | 59220 | 59686 | 64379803 |
Burning sensation | 11.84 | 11.27 | 17 | 59226 | 49647 | 64389842 |
Neutrophil Pelger-Huet anomaly present | 11.83 | 11.27 | 6 | 59237 | 347 | 64439142 |
Vocal cord thickening | 11.78 | 11.27 | 4 | 59239 | 82 | 64439407 |
Pulmonary alveolar haemorrhage | 11.78 | 11.27 | 27 | 59216 | 9711 | 64429778 |
Leuconostoc infection | 11.76 | 11.27 | 3 | 59240 | 21 | 64439468 |
Overdose | 11.75 | 11.27 | 92 | 59151 | 159474 | 64280015 |
Arteritis infective | 11.73 | 11.27 | 4 | 59239 | 83 | 64439406 |
Oropharyngeal pain | 11.73 | 11.27 | 42 | 59201 | 88825 | 64350664 |
Intentional self-injury | 11.73 | 11.27 | 6 | 59237 | 29038 | 64410451 |
Vision blurred | 11.71 | 11.27 | 43 | 59200 | 90273 | 64349216 |
White blood cell count increased | 11.70 | 11.27 | 102 | 59141 | 65912 | 64373577 |
Septic embolus | 11.70 | 11.27 | 11 | 59232 | 1751 | 64437738 |
Vascular anastomotic haemorrhage | 11.69 | 11.27 | 4 | 59239 | 84 | 64439405 |
Metastatic malignant melanoma | 11.66 | 11.27 | 13 | 59230 | 2528 | 64436961 |
Glomerular filtration rate decreased | 11.62 | 11.27 | 42 | 59201 | 19530 | 64419959 |
Encapsulating peritoneal sclerosis | 11.61 | 11.27 | 8 | 59235 | 817 | 64438672 |
Toxicity to various agents | 11.61 | 11.27 | 250 | 58993 | 363263 | 64076226 |
Perineal cyst | 11.60 | 11.27 | 4 | 59239 | 86 | 64439403 |
Therapy change | 11.54 | 11.27 | 21 | 59222 | 6413 | 64433076 |
Bronchitis | 11.50 | 11.27 | 56 | 59187 | 108687 | 64330802 |
Escherichia bacteraemia | 11.47 | 11.27 | 19 | 59224 | 5384 | 64434105 |
Mycobacterium fortuitum infection | 11.42 | 11.27 | 5 | 59238 | 207 | 64439282 |
Viral skin infection | 11.39 | 11.27 | 4 | 59239 | 91 | 64439398 |
Herpes zoster cutaneous disseminated | 11.34 | 11.27 | 6 | 59237 | 379 | 64439110 |
Cutaneous tuberculosis | 11.31 | 11.27 | 5 | 59238 | 212 | 64439277 |
None
Source | Code | Description |
---|---|---|
ATC | L04AA06 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Selective immunosuppressants |
MeSH PA | D000900 | Anti-Bacterial Agents |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D000903 | Antibiotics, Antineoplastic |
MeSH PA | D000904 | Antibiotics, Antitubercular |
MeSH PA | D000970 | Antineoplastic Agents |
MeSH PA | D000995 | Antitubercular Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
FDA EPC | N0000175613 | Antimetabolite Immunosuppressant |
CHEBI has role | CHEBI:35705 | immunosuppressive agents |
CHEBI has role | CHEBI:53746 | EC 1.1.1.205 inhibitor |
CHEBI has role | CHEBI:25442 | mycotoxins |
CHEBI has role | CHEBI:33281 | antibiotics |
CHEBI has role | CHEBI:35610 | antineoplastic agents |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:76964 | Penicillium metabolites |
CHEBI has role | CHEBI:78298 | environmental contaminants |
CHEBI has role | CHEBI:149553 | anticoronaviral drug |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Prevention of Liver Transplant Rejection | indication | ||
Prevention of Cardiac Transplant Rejection | indication | ||
Prevention of Kidney Transplant Rejection | indication | ||
Prevention of Lung Transplant Rejection | off-label use | ||
Herpes zoster | contraindication | 4740000 | DOID:8536 |
Progressive multifocal leukoencephalopathy | contraindication | 22255007 | DOID:643 |
Cytomegalovirus infection | contraindication | 28944009 | |
Constitutional aplastic anemia | contraindication | 28975000 | DOID:1342 |
Gastrointestinal ulcer | contraindication | 40845000 | |
Gastrointestinal perforation | contraindication | 51875005 | |
Acute nephropathy | contraindication | 58574008 | |
Acute infectious disease | contraindication | 63171007 | |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Herpes simplex | contraindication | 88594005 | DOID:8566 |
Malignant lymphoma | contraindication | 118600007 | DOID:0060058 |
Deficiency of hypoxanthine phosphoribosyltransferase | contraindication | 124275001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Pregnancy, function | contraindication | 289908002 | |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Bone marrow depression | contraindication | 307762000 | |
Primary malignant neoplasm | contraindication | 372087000 | |
Malignant neoplasm of skin | contraindication | 372130007 | DOID:4159 |
Breastfeeding (mother) | contraindication | 413712001 | |
Opportunistic Fungal Infection | contraindication | ||
BK Polyomavirus Reactivation Nephropathy | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.67 | acidic |
pKa2 | 11.03 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Inosine-5'-monophosphate dehydrogenase (IMPDH) | Enzyme | INHIBITOR | IC50 | 4.70 | CHEMBL | CHEMBL | |||
Inosine-5'-monophosphate dehydrogenase 1 | Enzyme | Ki | 7.48 | CHEMBL | |||||
Inosine-5'-monophosphate dehydrogenase 2 | Enzyme | Ki | 8.22 | CHEMBL | |||||
Inosine-5'-monophosphate dehydrogenase | Unclassified | IC50 | 6.92 | CHEMBL |
ID | Source |
---|---|
4025608 | VUID |
N0000176078 | NUI |
D05095 | KEGG_DRUG |
4021418 | VANDF |
4025598 | VANDF |
4025608 | VANDF |
C0026933 | UMLSCUI |
CHEBI:168396 | CHEBI |
MOA | PDB_CHEM_ID |
CHEMBL866 | ChEMBL_ID |
DB01024 | DRUGBANK_ID |
CHEMBL2106643 | ChEMBL_ID |
D009173 | MESH_DESCRIPTOR_UI |
446541 | PUBCHEM_CID |
6832 | IUPHAR_LIGAND_ID |
2950 | INN_ID |
HU9DX48N0T | UNII |
265323 | RXNORM |
18132 | MMSL |
210716 | MMSL |
d05217 | MMSL |
005013 | NDDF |
009984 | NDDF |
409330005 | SNOMEDCT_US |
409331009 | SNOMEDCT_US |
426216009 | SNOMEDCT_US |
24280-93-1 | SECONDARY_CAS_RN |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Myfortic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0385 | TABLET, DELAYED RELEASE | 180 mg | ORAL | NDA | 29 sections |
Myfortic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0385 | TABLET, DELAYED RELEASE | 180 mg | ORAL | NDA | 29 sections |
Myfortic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0386 | TABLET, DELAYED RELEASE | 360 mg | ORAL | NDA | 29 sections |
Myfortic | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0078-0386 | TABLET, DELAYED RELEASE | 360 mg | ORAL | NDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-4201 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-4202 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6785 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6785 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6786 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6786 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-189 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 27 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16729-261 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 27 sections |
mycophenolic acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-160 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 29 sections |
mycophenolic acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-161 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-559 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-560 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51079-508 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51079-509 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 29 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60429-016 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60429-017 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-2965 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-2965 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-2966 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-2966 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 23 sections |
MYCOPHENOLIC ACID | Human Prescription Drug Label | 1 | 67877-426 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 28 sections |
MYCOPHENOLIC ACID | Human Prescription Drug Label | 1 | 67877-427 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 28 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68084-907 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 26 sections |
Mycophenolic Acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68084-918 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 26 sections |
mycophenolic acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68254-5001 | TABLET, DELAYED RELEASE | 180 mg | ORAL | ANDA | 26 sections |
mycophenolic acid | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68254-5002 | TABLET, DELAYED RELEASE | 360 mg | ORAL | ANDA | 26 sections |