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5-aminolevulinic acid hexyl ester 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 167 | 140898-97-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IGF1R,IKBKB,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 | 57 | |||
| kinase-selectivity-class | AXL,BRAF,EPHB4,GRK2,MAP2K6,MAPK7,PDK4,STK33,TEK | 9 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| May 28, 2010 | FDA | PHOTOCURE ASA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V04CX06 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Other diagnostic agents |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
Related Drugs by ATC class:
V04CX Other diagnostic agents 9 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.43 | Basic |
Orange Book patent data (new drug applications)
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
|---|---|---|---|---|---|---|---|---|---|---|
| 100MG/VIAL | CYSVIEW KIT | PHOTOCURE ASA | N022555 | May 28, 2010 | RX | FOR SOLUTION | INTRAVESICAL | 10556010 | Dec. 19, 2036 | DETECTION OF CARCINOMA IN THE BLADDER BY PHOTODYNAMIC CYSTOSCOPY |
| 100MG/VIAL | CYSVIEW KIT | PHOTOCURE ASA | N022555 | May 28, 2010 | RX | FOR SOLUTION | INTRAVESICAL | 11311620 | Dec. 19, 2036 | DETECTION OF CARCINOMA IN THE BLADDER BY PHOTODYNAMIC CYSTOSCOPY |
| 100MG/VIAL | CYSVIEW KIT | PHOTOCURE ASA | N022555 | May 28, 2010 | RX | FOR SOLUTION | INTRAVESICAL | 11235168 | Jan. 4, 2038 | DETECTION OF CARCINOMA IN THE BLADDER BY PHOTODYNAMIC CYSTOSCOPY |
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4030912 | VUID |
| N0000182977 | NUI |
| D04436 | KEGG_DRUG |
| 1426871 | RXNORM |
| C1327841 | UMLSCUI |
| 6433083 | PUBCHEM_CID |
| CHEMBL1201784 | ChEMBL_ID |
| C419924 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB06261 | DRUGBANK_ID |
| 30199 | MMSL |
| d06771 | MMSL |
| CHEBI:134892 | CHEBI |
| CHEMBL1201785 | ChEMBL_ID |
| 140898-91-5 | SECONDARY_CAS_RN |
| G7H20TKI67 | UNII |
| 4030909 | VANDF |
| 4030912 | VANDF |
| 012185 | NDDF |
| 012186 | NDDF |
| 769100005 | SNOMEDCT_US |
| 899901000168103 | SNOMEDCT_US |
Pharmaceutical products:
None