Molfile
Inchi
Smiles
Synonyms:
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methacholine chloride
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methacholine
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acetylmethylcholine
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mecholin
-
mecholine
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methacholin
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beta-methylacetylcholine
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A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)
- Molecular weight: 160.24
- Formula: C8H18NO2
- CLOGP: -3.16
- LIPINSKI: 0
- HAC: 3
- HDO: 0
- TPSA: 26.30
- ALOGS: -3.46
- ROTB: 4
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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