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UREA C-13 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4323 | 58069-82-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT3,ALK,AURKA,AURKB,AURKC,AXL,BMX,BRAF,CAMK2B,CAMK2D,CDK1,CDK2,CDK3,CDK5,CDK9,CHEK1,CLK4,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FGFR1,FLT3,GRK2,GSK3B,IKBKB,IRAK1,IRAK3,ITK,JAK1,JAK2,KDR,KIT,LYN,MAP2K6,MAP3K1,MAP3K10,MAP3K11,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAP4K3,MAP4K5,MAPK7,MAPK9,MARK4,MET,MTOR,NTRK1,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2 | 79 | |||
| kinase-selectivity-class | AAK1,ACVR2A,ACVR2B,ALK,AURKA,AXL,BMX,BRAF,CAMK2B,CAMK2D,CDK1,CDK9,CSF1R,DDR1,DYRK1B,EGFR,EIF2AK3,FGFR1,FLT3,GRK2,IKBKB,IRAK1,JAK1,JAK2,LRRK2,MAP2K3,MAP2K6,MAP3K10,MAP3K11,MAP3K14,MAP3K21,MAP4K1,MAP4K3,MAPK7,MARK4,NTRK1,NUAK1,PRKCD,SIK2,SIK3,STK33,STK4,TEK,TNK1,TTK,ULK1,ULK2 | 47 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Sept. 17, 1996 | FDA | OTSUKA AMERICA | |
| Aug. 14, 1997 | EMA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V04CX05 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Other diagnostic agents |
| FDA CS | M0003375 | Carbon Radioisotopes |
| FDA CS | M0018403 | Radioactive Tracers |
| FDA CS | M0022315 | Urea |
| FDA EPC | N0000175886 | Helicobacter pylori Diagnostic |
Related Drugs by ATC class:
V04CX Other diagnostic agents 9 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Helicobacter pylori breath test | indication | 164791003 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.96 | acidic |
| pKa2 | 13.39 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| CHEBI:32285 | CHEBI |
| CHEMBL2096648 | ChEMBL_ID |
| DB09510 | DRUGBANK_ID |
| W6KX9E6D8X | UNII |
| 226724 | RXNORM |
| 006325 | NDDF |
| 317887006 | SNOMEDCT_US |
| 395918001 | SNOMEDCT_US |
| C0732290 | UMLSCUI |
| 636363 | PUBCHEM_CID |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| IDkit HP ONE | HUMAN PRESCRIPTION DRUG LABEL | 2 | 50402-100 | SOLUTION | 75 mg | ORAL | NDA | 2 sections |
| 72H BODY HEAT | HUMAN OTC DRUG LABEL | 2 | 84025-061 | POULTICE | 2 mg | CUTANEOUS | OTC Monograph Drug | 6 sections |