hetacillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibiotics, 6-aminopenicillanic acid derivatives | 1363 | 3511-16-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 2 | g | O |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | BRISTOL |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01CA18 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE BETA-LACTAM ANTIBACTERIALS, PENICILLINS Penicillins with extended spectrum |
| CHEBI has role | CHEBI:36047 | antibacterial drugs |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Respiratory tract infections | Indication |
| Cats | Urinary tract infections | Indication |
| Cats | Gastrointestinal infections | Indication |
| Cats | Skin infections | Indication |
| Cats | Soft tissue infections | Indication |
| Cats | Postsurgical infections | Indication |
| Cattle | Acute bovine mastitis | Indication |
| Cattle | Chronic bovine mastitis | Indication |
| Cattle | Subclinical bovine mastitis | Indication |
| Dogs | Respiratory tract infections | Indication |
| Dogs | Urinary tract infections | Indication |
| Dogs | Gastrointestinal infections | Indication |
| Dogs | Skin infections | Indication |
| Dogs | Soft tissue infections | Indication |
| Dogs | Postsurgical infections | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Hetacin K Capsules Vet | Boehringer lngelheim Animal Health USA Inc. | 1 |
| Hetacin K Tablets | Boehringer lngelheim Animal Health USA Inc. | 1 |
| Hetacin K Oral Liquid | Boehringer lngelheim Animal Health USA Inc. | 1 |
| PolyMast Intramammary Infusion | Boehringer lngelheim Animal Health USA Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 3.03 | acidic |
| pKa2 | 5.46 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Penicillin-binding protein | Enzyme | INHIBITOR | CHEMBL | CHEMBL |
External reference:
| ID | Source |
|---|---|
| D01074 | KEGG_DRUG |
| 5321-32-4 | SECONDARY_CAS_RN |
| C0062587 | UMLSCUI |
| CHEBI:5683 | CHEBI |
| CHEMBL1201116 | ChEMBL_ID |
| CHEMBL1201121 | ChEMBL_ID |
| DB00739 | DRUGBANK_ID |
| C100115 | MESH_SUPPLEMENTAL_RECORD_UI |
| 443387 | PUBCHEM_CID |
| 12263 | IUPHAR_LIGAND_ID |
| 1924 | INN_ID |
| TN4JSC48CV | UNII |
| 1299048 | RXNORM |
| 002705 | NDDF |
| 002706 | NDDF |
| 37691005 | SNOMEDCT_US |
Pharmaceutical products:
None