etilamfetamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anorexics 1100 457-87-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • etilamfetamine
  • (+/-)-Ethylamphetamine
  • 2-Ethylamino-1-phenylpropane
  • apetinil
  • ethylamphetamine
  • N-Ethylamphetamine
  • ethylamphetamine hydrochloride
  • ethylamphetamine HCl
  • Molecular weight: 163.26
  • Formula: C11H17N
  • CLOGP: 2.42
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 1
  • TPSA: 12.03
  • ALOGS: -2.77
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A08AA06 ALIMENTARY TRACT AND METABOLISM
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
Centrally acting antiobesity products

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.85 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Sigma non-opioid intracellular receptor 1 Membrane receptor Ki 6.18 CHEMBL

External reference:

IDSource
D07114 KEGG_DRUG
C0059791 UMLSCUI
CHEBI:134796 CHEBI
CHEMBL276443 ChEMBL_ID
DB13285 DRUGBANK_ID
CHEMBL1907646 ChEMBL_ID
9982 PUBCHEM_CID
4532 INN_ID
C016434 MESH_SUPPLEMENTAL_RECORD_UI
022YON1XMX UNII
786882006 SNOMEDCT_US

Pharmaceutical products:

None