cathine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
3389 492-39-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • (+)-Norpseudoephedrine
  • norpseudoephedrine
  • cathine
  • pseudonorephedrine
major metabolite of diethylpropion in man under acidic urine conditions; RN given refers to cpd without isomeric designation
  • Molecular weight: 151.21
  • Formula: C9H13NO
  • CLOGP: 0.58
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 2
  • TPSA: 46.25
  • ALOGS: -0.87
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AKT2,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,ITK,MAP3K7,MAPK12,MAPK7,NTRK2,PDK2,PIM2,PRKDC,SIK2,SYK,TEK,TGFBR1 27
kinase-selectivity-class AKT3,AXL,GRK2,PDK4 4
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A08AA07 ALIMENTARY TRACT AND METABOLISM
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS
Centrally acting antiobesity products
MeSH PA D001067 Appetite Depressants
MeSH PA D019440 Anti-Obesity Agents
CHEBI has role CHEBI:35337 central nervous system stimulant
CHEBI has role CHEBI:35471 psychotropic drug
CHEBI has role CHEBI:74518 anti-obesity agent
CHEBI has role CHEBI:76924 plant metabolite

Related Drugs by ATC class:

A08AA Centrally acting antiobesity products 15 drugs
bupropionclobenzorexdexfenfluraminediethylpropionephedrineetilamfetaminefenfluraminelorcaserinmazindolmefenorexnaltrexonephentermine show all 15 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.86 acidic
pKa2 8.89 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07627 KEGG_DRUG
C0069021 UMLSCUI
CHEMBL1412041 ChEMBL_ID
DB01486 DRUGBANK_ID
C005331 MESH_SUPPLEMENTAL_RECORD_UI
4952 INN_ID
E1L4ZW2F8O UNII
441457 PUBCHEM_CID
32022 RXNORM
007019 NDDF
96257008 SNOMEDCT_US
CHEBI:4109 CHEBI
36393-56-3 SECONDARY_CAS_RN

Pharmaceutical products:

None