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eritrityl tetranitrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| NO2 - derivatives | 1047 | 7297-25-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A vasodilator with general properties similar to NITROGLYCERIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1020)
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 90 | mg | O |
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,AKT3,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,GRK2,GSK3B,IGF1R,ITK,JAK1,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK8,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1,ZAP70 | 61 | |||
| kinase-selectivity-class | AURKA,AXL,BRAF,CDK2,CDK4,CDK9,DDR1,DYRK1B,EPHB4,ERBB2,GRK2,GSK3A,GSK3B,IRAK1,MAP2K3,MAP2K6,MAPK1,MAPK7,MAPK8,MET,PDK4,PRKDC,SIK2,STK33,SYK,TEK,TTK,UHMK1 | 28 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C01DA13 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY VASODILATORS USED IN CARDIAC DISEASES Organic nitrates |
| ATC | C01DA63 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY VASODILATORS USED IN CARDIAC DISEASES Organic nitrates |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D014665 | Vasodilator Agents |
| CHEBI has role | CHEBI:35554 | cardiovascular drug |
| CHEBI has role | CHEBI:35620 | vasodilator agent |
| CHEBI has role | CHEBI:63490 | explosive |
Related Drugs by ATC class:
C01DA Organic nitrates 7 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4018764 | VUID |
| N0000147067 | NUI |
| D04051 | KEGG_DRUG |
| 4018764 | VANDF |
| CHEBI:60072 | CHEBI |
| CHEMBL2107583 | ChEMBL_ID |
| CHEMBL453636 | ChEMBL_ID |
| DB01613 | DRUGBANK_ID |
| 4040 | RXNORM |
| 000685 | NDDF |
| 398960003 | SNOMEDCT_US |
| 62368002 | SNOMEDCT_US |
| C0014758 | UMLSCUI |
| D004897 | MESH_DESCRIPTOR_UI |
| 5284553 | PUBCHEM_CID |
| 1448 | INN_ID |
| 35X333P19D | UNII |
Pharmaceutical products:
None