Stem definition | Drug id | CAS RN |
---|---|---|
NO2 - derivatives | 1952 | 55-63-0 |
Dose | Unit | Route |
---|---|---|
5 | mg | O |
2.50 | mg | oral aerosol |
2.50 | mg | SL |
5 | mg | TD |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.80 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.64 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 1 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
CL (Clearance) | 194.30 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.40 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 4.50 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
May 28, 1981 | FDA | FOUGERA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Myocardial infarction | 826.35 | 10.33 | 795 | 57146 | 96733 | 46531388 |
Coronary artery disease | 389.62 | 10.33 | 328 | 57613 | 33424 | 46594697 |
Angina pectoris | 350.53 | 10.33 | 280 | 57661 | 26495 | 46601626 |
Cardiac failure congestive | 338.72 | 10.33 | 489 | 57452 | 91261 | 46536860 |
Acute myocardial infarction | 325.43 | 10.33 | 289 | 57652 | 31635 | 46596486 |
Chest pain | 319.69 | 10.33 | 687 | 57254 | 175637 | 46452484 |
Orthostatic hypotension | 210.07 | 10.33 | 202 | 57739 | 24456 | 46603665 |
Angina unstable | 208.37 | 10.33 | 125 | 57816 | 7423 | 46620698 |
Sedation complication | 148.67 | 10.33 | 78 | 57863 | 3567 | 46624554 |
Renal failure | 144.29 | 10.33 | 386 | 57555 | 113208 | 46514913 |
Coronary arterial stent insertion | 130.65 | 10.33 | 66 | 57875 | 2787 | 46625334 |
Renal injury | 127.41 | 10.33 | 101 | 57840 | 9440 | 46618681 |
Creatinine renal clearance decreased | 125.41 | 10.33 | 88 | 57853 | 6832 | 46621289 |
Acute coronary syndrome | 119.37 | 10.33 | 100 | 57841 | 10104 | 46618017 |
Fear | 114.75 | 10.33 | 120 | 57821 | 16052 | 46612069 |
Rheumatoid arthritis | 110.69 | 10.33 | 82 | 57859 | 240133 | 46387988 |
Injury | 101.59 | 10.33 | 190 | 57751 | 43837 | 46584284 |
Hypotension | 97.09 | 10.33 | 555 | 57386 | 232034 | 46396087 |
Bradycardia | 96.22 | 10.33 | 237 | 57704 | 66061 | 46562060 |
Anhedonia | 90.52 | 10.33 | 86 | 57855 | 10249 | 46617872 |
Gastrointestinal haemorrhage | 90.29 | 10.33 | 255 | 57686 | 77118 | 46551003 |
Off label use | 87.40 | 10.33 | 216 | 57725 | 379625 | 46248496 |
Drug ineffective | 85.32 | 10.33 | 494 | 57447 | 677344 | 45950777 |
Sedation | 82.74 | 10.33 | 121 | 57820 | 22789 | 46605332 |
Cerebrovascular accident | 82.16 | 10.33 | 294 | 57647 | 100745 | 46527376 |
Blood calcium decreased | 81.60 | 10.33 | 99 | 57842 | 15574 | 46612547 |
Emotional distress | 80.36 | 10.33 | 140 | 57801 | 30567 | 46597554 |
Coronary artery occlusion | 77.86 | 10.33 | 71 | 57870 | 8031 | 46620090 |
Fall | 73.16 | 10.33 | 675 | 57266 | 328422 | 46299699 |
Labile blood pressure | 71.04 | 10.33 | 37 | 57904 | 1666 | 46626455 |
Myocardial ischaemia | 68.77 | 10.33 | 82 | 57859 | 12667 | 46615454 |
Balance disorder | 66.04 | 10.33 | 203 | 57738 | 64318 | 46563803 |
Treatment failure | 66.04 | 10.33 | 17 | 57924 | 93070 | 46535051 |
Cognitive disorder | 63.48 | 10.33 | 141 | 57800 | 36742 | 46591379 |
Peripheral vascular disorder | 62.63 | 10.33 | 55 | 57886 | 5922 | 46622199 |
Transient ischaemic attack | 60.71 | 10.33 | 134 | 57807 | 34769 | 46593352 |
Cardiac disorder | 60.68 | 10.33 | 154 | 57787 | 43704 | 46584417 |
Hyperkalaemia | 59.99 | 10.33 | 168 | 57773 | 50541 | 46577580 |
Syncope | 58.91 | 10.33 | 272 | 57669 | 104531 | 46523590 |
Atrial fibrillation | 56.13 | 10.33 | 266 | 57675 | 103324 | 46524797 |
Febrile neutropenia | 55.41 | 10.33 | 24 | 57917 | 94603 | 46533518 |
Unevaluable event | 52.68 | 10.33 | 151 | 57790 | 46024 | 46582097 |
Neutropenia | 50.55 | 10.33 | 62 | 57879 | 143142 | 46484979 |
Drug abuse | 50.22 | 10.33 | 9 | 57932 | 63399 | 46564722 |
Pyrexia | 48.17 | 10.33 | 246 | 57695 | 348556 | 46279565 |
Depressed level of consciousness | 48.05 | 10.33 | 149 | 57792 | 47420 | 46580701 |
Maternal exposure during pregnancy | 47.16 | 10.33 | 35 | 57906 | 102514 | 46525607 |
Cardiac failure | 46.78 | 10.33 | 210 | 57731 | 79738 | 46548383 |
Renal impairment | 46.28 | 10.33 | 199 | 57742 | 74173 | 46553948 |
Contraindicated product administered | 45.66 | 10.33 | 21 | 57920 | 79926 | 46548195 |
Abortion spontaneous | 42.51 | 10.33 | 3 | 57938 | 43643 | 46584478 |
Oesophageal spasm | 42.48 | 10.33 | 28 | 57913 | 1961 | 46626160 |
Alopecia | 42.43 | 10.33 | 86 | 57855 | 162328 | 46465793 |
Ischaemic cardiomyopathy | 42.26 | 10.33 | 31 | 57910 | 2579 | 46625542 |
Acute kidney injury | 39.54 | 10.33 | 457 | 57484 | 235398 | 46392723 |
Arteriospasm coronary | 39.31 | 10.33 | 34 | 57907 | 3587 | 46624534 |
Troponin increased | 38.47 | 10.33 | 48 | 57893 | 7768 | 46620353 |
Infusion related reaction | 37.66 | 10.33 | 42 | 57899 | 101166 | 46526955 |
Hypoglycaemia | 37.40 | 10.33 | 150 | 57791 | 54199 | 46573922 |
Coronary artery bypass | 37.26 | 10.33 | 28 | 57913 | 2417 | 46625704 |
Intentional overdose | 37.18 | 10.33 | 17 | 57924 | 64927 | 46563194 |
Chronic obstructive pulmonary disease | 34.92 | 10.33 | 153 | 57788 | 57480 | 46570641 |
White blood cell count decreased | 34.18 | 10.33 | 54 | 57887 | 112177 | 46515944 |
Bursitis infective | 33.80 | 10.33 | 20 | 57921 | 1157 | 46626964 |
Arteriosclerosis coronary artery | 33.77 | 10.33 | 46 | 57895 | 8110 | 46620011 |
Drug intolerance | 33.41 | 10.33 | 84 | 57857 | 146965 | 46481156 |
Abdominal discomfort | 33.08 | 10.33 | 88 | 57853 | 151077 | 46477044 |
Systemic lupus erythematosus | 32.98 | 10.33 | 20 | 57921 | 65160 | 46562961 |
Pulmonary oedema | 32.75 | 10.33 | 138 | 57803 | 50967 | 46577154 |
Injection site pain | 32.21 | 10.33 | 52 | 57889 | 107100 | 46521021 |
Suicide attempt | 32.14 | 10.33 | 14 | 57927 | 55022 | 46573099 |
Coronary artery stenosis | 31.70 | 10.33 | 34 | 57907 | 4679 | 46623442 |
Cardiac arrest | 31.45 | 10.33 | 206 | 57735 | 90193 | 46537928 |
Sinus arrest | 31.33 | 10.33 | 22 | 57919 | 1709 | 46626412 |
Hyponatraemia | 31.15 | 10.33 | 224 | 57717 | 101108 | 46527013 |
Prinzmetal angina | 30.34 | 10.33 | 16 | 57925 | 739 | 46627382 |
Hepatic ischaemia | 30.09 | 10.33 | 14 | 57927 | 492 | 46627629 |
Product dose omission issue | 29.86 | 10.33 | 108 | 57833 | 168412 | 46459709 |
Cardiac murmur | 29.83 | 10.33 | 52 | 57889 | 11352 | 46616769 |
Completed suicide | 29.66 | 10.33 | 88 | 57853 | 145832 | 46482289 |
Dyspnoea | 29.38 | 10.33 | 842 | 57099 | 514706 | 46113415 |
Sinus node dysfunction | 28.95 | 10.33 | 31 | 57910 | 4258 | 46623863 |
Injection site pruritus | 28.67 | 10.33 | 7 | 57934 | 39736 | 46588385 |
Product solubility abnormal | 28.53 | 10.33 | 16 | 57925 | 836 | 46627285 |
Injection site reaction | 28.21 | 10.33 | 12 | 57929 | 47837 | 46580284 |
Exposure during pregnancy | 27.65 | 10.33 | 58 | 57883 | 108154 | 46519967 |
Injection site erythema | 27.56 | 10.33 | 31 | 57910 | 74396 | 46553725 |
Muscle relaxant therapy | 27.42 | 10.33 | 9 | 57932 | 120 | 46628001 |
Hand deformity | 27.17 | 10.33 | 5 | 57936 | 34569 | 46593552 |
Lower gastrointestinal haemorrhage | 26.91 | 10.33 | 39 | 57902 | 7281 | 46620840 |
Hyperkeratosis | 26.57 | 10.33 | 32 | 57909 | 4993 | 46623128 |
Malignant neoplasm progression | 26.35 | 10.33 | 25 | 57916 | 64901 | 46563220 |
Hepatic enzyme increased | 26.20 | 10.33 | 38 | 57903 | 81749 | 46546372 |
Stress | 26.18 | 10.33 | 130 | 57811 | 51421 | 46576700 |
Disease progression | 25.88 | 10.33 | 46 | 57895 | 91254 | 46536867 |
Product use issue | 25.66 | 10.33 | 49 | 57892 | 94595 | 46533526 |
Fear of eating | 24.98 | 10.33 | 11 | 57930 | 339 | 46627782 |
Condition aggravated | 24.86 | 10.33 | 190 | 57751 | 244862 | 46383259 |
Haemorrhage | 24.84 | 10.33 | 134 | 57807 | 54735 | 46573386 |
Nasopharyngitis | 24.52 | 10.33 | 103 | 57838 | 153895 | 46474226 |
International normalised ratio increased | 24.36 | 10.33 | 119 | 57822 | 46764 | 46581357 |
Confusional state | 23.78 | 10.33 | 303 | 57638 | 159589 | 46468532 |
Psoriasis | 23.76 | 10.33 | 38 | 57903 | 78566 | 46549555 |
Hyperlipidaemia | 23.48 | 10.33 | 63 | 57878 | 18476 | 46609645 |
Glossodynia | 23.32 | 10.33 | 13 | 57928 | 44360 | 46583761 |
Left ventricular dysfunction | 23.32 | 10.33 | 44 | 57897 | 10211 | 46617910 |
Coronary artery dissection | 23.22 | 10.33 | 13 | 57928 | 677 | 46627444 |
Anxiety | 23.04 | 10.33 | 335 | 57606 | 181622 | 46446499 |
Sinus bradycardia | 22.93 | 10.33 | 52 | 57889 | 13730 | 46614391 |
Arthralgia | 22.84 | 10.33 | 317 | 57624 | 364286 | 46263835 |
Infection | 22.75 | 10.33 | 87 | 57854 | 133505 | 46494616 |
Angioplasty | 22.69 | 10.33 | 16 | 57925 | 1251 | 46626870 |
Drug interaction | 22.68 | 10.33 | 366 | 57575 | 202728 | 46425393 |
Haematemesis | 22.68 | 10.33 | 83 | 57858 | 28723 | 46599398 |
Autonomic dysreflexia | 22.65 | 10.33 | 9 | 57932 | 213 | 46627908 |
Mucosal inflammation | 22.62 | 10.33 | 10 | 57931 | 38966 | 46589155 |
Joint swelling | 22.37 | 10.33 | 118 | 57823 | 165955 | 46462166 |
Presyncope | 22.32 | 10.33 | 74 | 57867 | 24380 | 46603741 |
Acute pulmonary oedema | 21.98 | 10.33 | 37 | 57904 | 7854 | 46620267 |
Rash | 21.97 | 10.33 | 311 | 57630 | 356201 | 46271920 |
Melaena | 21.85 | 10.33 | 80 | 57861 | 27692 | 46600429 |
Diarrhoea | 21.75 | 10.33 | 529 | 57412 | 559073 | 46069048 |
Cardiomegaly | 21.73 | 10.33 | 59 | 57882 | 17423 | 46610698 |
Hepatorenal syndrome | 21.73 | 10.33 | 18 | 57923 | 1790 | 46626331 |
Percutaneous coronary intervention | 21.72 | 10.33 | 8 | 57933 | 153 | 46627968 |
Arterial occlusive disease | 21.28 | 10.33 | 28 | 57913 | 4776 | 46623345 |
Arthropathy | 21.13 | 10.33 | 46 | 57895 | 84654 | 46543467 |
Blood loss anaemia | 21.07 | 10.33 | 38 | 57903 | 8519 | 46619602 |
Dermatitis bullous | 20.19 | 10.33 | 35 | 57906 | 7608 | 46620513 |
Pituitary apoplexy | 20.16 | 10.33 | 7 | 57934 | 112 | 46628009 |
Hypertension | 19.78 | 10.33 | 348 | 57593 | 196008 | 46432113 |
Neutrophil count decreased | 19.72 | 10.33 | 15 | 57926 | 43411 | 46584710 |
Chronic kidney disease | 19.31 | 10.33 | 101 | 57840 | 40770 | 46587351 |
Atrioventricular block | 19.06 | 10.33 | 32 | 57909 | 6779 | 46621342 |
Product use in unapproved indication | 18.65 | 10.33 | 54 | 57887 | 90219 | 46537902 |
Colitis microscopic | 18.61 | 10.33 | 31 | 57910 | 6525 | 46621596 |
Hypovolaemia | 18.37 | 10.33 | 39 | 57902 | 9849 | 46618272 |
Therapeutic product effect decreased | 18.12 | 10.33 | 48 | 57893 | 82553 | 46545568 |
Synovitis | 18.01 | 10.33 | 30 | 57911 | 61045 | 46567076 |
Laryngotracheal oedema | 17.99 | 10.33 | 5 | 57936 | 36 | 46628085 |
Ventricular tachycardia | 17.92 | 10.33 | 54 | 57887 | 16913 | 46611208 |
Fatigue | 17.90 | 10.33 | 598 | 57343 | 608099 | 46020022 |
Bundle branch block left | 17.82 | 10.33 | 30 | 57911 | 6369 | 46621752 |
Duodenal ulcer | 17.70 | 10.33 | 32 | 57909 | 7186 | 46620935 |
Device dislocation | 17.47 | 10.33 | 3 | 57938 | 21799 | 46606322 |
Psoriatic arthropathy | 17.26 | 10.33 | 12 | 57929 | 36367 | 46591754 |
Mitral valve incompetence | 17.16 | 10.33 | 57 | 57884 | 18795 | 46609326 |
Leukopenia | 17.14 | 10.33 | 37 | 57904 | 68306 | 46559815 |
Coronary artery reocclusion | 17.11 | 10.33 | 5 | 57936 | 44 | 46628077 |
Electrocardiogram ST segment elevation | 17.09 | 10.33 | 22 | 57919 | 3673 | 46624448 |
Silent myocardial infarction | 16.81 | 10.33 | 9 | 57932 | 429 | 46627692 |
Coronary artery restenosis | 16.79 | 10.33 | 9 | 57932 | 430 | 46627691 |
Sputum discoloured | 16.77 | 10.33 | 44 | 57897 | 12734 | 46615387 |
Reperfusion arrhythmia | 16.63 | 10.33 | 5 | 57936 | 49 | 46628072 |
Bone marrow failure | 16.62 | 10.33 | 8 | 57933 | 29661 | 46598460 |
Lip swelling | 16.60 | 10.33 | 69 | 57872 | 25326 | 46602795 |
Ventricular extrasystoles | 16.51 | 10.33 | 40 | 57901 | 11023 | 46617098 |
Left ventricular end-diastolic pressure increased | 16.47 | 10.33 | 8 | 57933 | 310 | 46627811 |
Laryngospasm | 16.36 | 10.33 | 19 | 57922 | 2854 | 46625267 |
Rectal haemorrhage | 16.36 | 10.33 | 92 | 57849 | 38163 | 46589958 |
Multiple organ dysfunction syndrome | 16.28 | 10.33 | 115 | 57826 | 51595 | 46576526 |
Sinusitis | 15.94 | 10.33 | 95 | 57846 | 129673 | 46498448 |
Swollen tongue | 15.76 | 10.33 | 75 | 57866 | 29157 | 46598964 |
Generalised tonic-clonic seizure | 15.67 | 10.33 | 7 | 57934 | 27115 | 46601006 |
Discoloured vomit | 15.62 | 10.33 | 9 | 57932 | 495 | 46627626 |
Pancytopenia | 15.39 | 10.33 | 54 | 57887 | 85004 | 46543117 |
Oedema peripheral | 15.35 | 10.33 | 281 | 57660 | 159425 | 46468696 |
C-reactive protein increased | 15.30 | 10.33 | 31 | 57910 | 58559 | 46569562 |
Bacteriuria | 15.08 | 10.33 | 10 | 57931 | 707 | 46627414 |
Troponin T increased | 14.97 | 10.33 | 11 | 57930 | 918 | 46627203 |
Neuropathy peripheral | 14.95 | 10.33 | 60 | 57881 | 90833 | 46537288 |
Cardiac failure chronic | 14.78 | 10.33 | 20 | 57921 | 3504 | 46624617 |
Injection site swelling | 14.70 | 10.33 | 17 | 57924 | 40310 | 46587811 |
Pruritus | 14.69 | 10.33 | 212 | 57729 | 242140 | 46385981 |
Intentional product use issue | 14.59 | 10.33 | 27 | 57914 | 52753 | 46575368 |
Coronary ostial stenosis | 14.57 | 10.33 | 5 | 57936 | 77 | 46628044 |
Herpes zoster | 14.46 | 10.33 | 40 | 57901 | 67832 | 46560289 |
Erythema | 14.34 | 10.33 | 111 | 57830 | 142709 | 46485412 |
Subdural haematoma | 14.33 | 10.33 | 42 | 57899 | 12955 | 46615166 |
Heart injury | 14.19 | 10.33 | 12 | 57929 | 1227 | 46626894 |
Catheterisation cardiac | 14.07 | 10.33 | 21 | 57920 | 4026 | 46624095 |
Headache | 14.02 | 10.33 | 470 | 57471 | 477882 | 46150239 |
Palmar-plantar erythrodysaesthesia syndrome | 13.99 | 10.33 | 4 | 57937 | 20447 | 46607674 |
Haematoma | 13.86 | 10.33 | 77 | 57864 | 31795 | 46596326 |
Ascites | 13.80 | 10.33 | 15 | 57926 | 36569 | 46591552 |
Peripheral ischaemia | 13.54 | 10.33 | 22 | 57919 | 4537 | 46623584 |
Musculoskeletal stiffness | 13.53 | 10.33 | 69 | 57872 | 97924 | 46530197 |
Device issue | 13.50 | 10.33 | 4 | 57937 | 19976 | 46608145 |
Cytomegalovirus infection | 13.47 | 10.33 | 3 | 57938 | 18141 | 46609980 |
Acne | 13.44 | 10.33 | 4 | 57937 | 19915 | 46608206 |
Arteriosclerosis | 13.27 | 10.33 | 34 | 57907 | 9699 | 46618422 |
Mobility decreased | 13.24 | 10.33 | 124 | 57817 | 60470 | 46567651 |
Oesophageal pain | 13.13 | 10.33 | 16 | 57925 | 2527 | 46625594 |
Dyspnoea exertional | 13.11 | 10.33 | 107 | 57834 | 50182 | 46577939 |
Vascular pseudoaneurysm | 13.08 | 10.33 | 12 | 57929 | 1368 | 46626753 |
Systolic anterior motion of mitral valve | 12.93 | 10.33 | 3 | 57938 | 9 | 46628112 |
Gastric haemorrhage | 12.92 | 10.33 | 25 | 57916 | 5909 | 46622212 |
Finger amputation | 12.69 | 10.33 | 8 | 57933 | 519 | 46627602 |
Ischaemia | 12.66 | 10.33 | 21 | 57920 | 4403 | 46623718 |
Non-cardiac chest pain | 12.50 | 10.33 | 25 | 57916 | 6053 | 46622068 |
Swelling | 12.39 | 10.33 | 97 | 57844 | 124414 | 46503707 |
Knee arthroplasty | 12.34 | 10.33 | 7 | 57934 | 23658 | 46604463 |
Atrioventricular block second degree | 12.20 | 10.33 | 19 | 57922 | 3780 | 46624341 |
Suicidal ideation | 12.18 | 10.33 | 33 | 57908 | 56349 | 46571772 |
Femur fracture | 12.03 | 10.33 | 17 | 57924 | 36980 | 46591141 |
Therapeutic response decreased | 11.99 | 10.33 | 22 | 57919 | 43123 | 46584998 |
Inappropriate schedule of product administration | 11.94 | 10.33 | 41 | 57900 | 64972 | 46563149 |
Discomfort | 11.93 | 10.33 | 25 | 57916 | 46645 | 46581476 |
Vascular graft | 11.91 | 10.33 | 9 | 57932 | 783 | 46627338 |
Periorbital haematoma | 11.90 | 10.33 | 9 | 57932 | 784 | 46627337 |
Arteriogram coronary abnormal | 11.89 | 10.33 | 3 | 57938 | 14 | 46628107 |
Arterial intramural haematoma | 11.89 | 10.33 | 3 | 57938 | 14 | 46628107 |
Cardiogenic shock | 11.89 | 10.33 | 46 | 57895 | 16338 | 46611783 |
No adverse event | 11.87 | 10.33 | 15 | 57926 | 34216 | 46593905 |
Throat irritation | 11.87 | 10.33 | 11 | 57930 | 28890 | 46599231 |
Mitral valve calcification | 11.84 | 10.33 | 10 | 57931 | 1021 | 46627100 |
Essential hypertension | 11.73 | 10.33 | 20 | 57921 | 4290 | 46623831 |
Stent placement | 11.72 | 10.33 | 18 | 57923 | 3538 | 46624583 |
Medication error | 11.70 | 10.33 | 72 | 57869 | 30839 | 46597282 |
Flushing | 11.70 | 10.33 | 41 | 57900 | 64573 | 46563548 |
Lupus myocarditis | 11.70 | 10.33 | 4 | 57937 | 61 | 46628060 |
Acquired epidermolysis bullosa | 11.64 | 10.33 | 4 | 57937 | 62 | 46628059 |
Hospitalisation | 11.63 | 10.33 | 40 | 57901 | 63345 | 46564776 |
Red blood cell sedimentation rate increased | 11.61 | 10.33 | 7 | 57934 | 22882 | 46605239 |
Drug eruption | 11.57 | 10.33 | 6 | 57935 | 21323 | 46606798 |
Reflux gastritis | 11.57 | 10.33 | 9 | 57932 | 818 | 46627303 |
Cardiomyopathy | 11.56 | 10.33 | 45 | 57896 | 16028 | 46612093 |
Hyperhidrosis | 11.51 | 10.33 | 165 | 57776 | 89143 | 46538978 |
Nephrogenic systemic fibrosis | 11.51 | 10.33 | 21 | 57920 | 4751 | 46623370 |
Constipation | 11.46 | 10.33 | 290 | 57651 | 173807 | 46454314 |
Colitis ischaemic | 11.42 | 10.33 | 33 | 57908 | 10099 | 46618022 |
Hypertensive heart disease | 11.38 | 10.33 | 15 | 57926 | 2563 | 46625558 |
Platelet count decreased | 11.37 | 10.33 | 75 | 57866 | 99949 | 46528172 |
Lethargy | 11.32 | 10.33 | 105 | 57836 | 51066 | 46577055 |
Sepsis | 11.30 | 10.33 | 111 | 57830 | 135903 | 46492218 |
Lymphadenopathy | 11.28 | 10.33 | 15 | 57926 | 33473 | 46594648 |
Total lung capacity decreased | 11.21 | 10.33 | 10 | 57931 | 1099 | 46627022 |
Multiple injuries | 11.17 | 10.33 | 13 | 57928 | 1956 | 46626165 |
Breast cancer | 11.12 | 10.33 | 25 | 57916 | 45493 | 46582628 |
Acute myeloid leukaemia | 10.96 | 10.33 | 3 | 57938 | 15775 | 46612346 |
Electrocardiogram T wave abnormal | 10.90 | 10.33 | 14 | 57927 | 2332 | 46625789 |
Nodal rhythm | 10.83 | 10.33 | 12 | 57929 | 1713 | 46626408 |
Therapeutic product effect incomplete | 10.81 | 10.33 | 55 | 57886 | 78098 | 46550023 |
Coronary artery thrombosis | 10.79 | 10.33 | 10 | 57931 | 1155 | 46626966 |
Ventricular hypertrophy | 10.78 | 10.33 | 18 | 57923 | 3796 | 46624325 |
Cardioactive drug level increased | 10.70 | 10.33 | 13 | 57928 | 2046 | 46626075 |
Leg amputation | 10.68 | 10.33 | 13 | 57928 | 2050 | 46626071 |
Patent ductus arteriosus | 10.61 | 10.33 | 18 | 57923 | 3844 | 46624277 |
Coagulation time abnormal | 10.56 | 10.33 | 4 | 57937 | 83 | 46628038 |
Stridor | 10.47 | 10.33 | 16 | 57925 | 3131 | 46624990 |
Mental status changes | 10.45 | 10.33 | 82 | 57859 | 38006 | 46590115 |
Hypoosmolar state | 10.36 | 10.33 | 5 | 57936 | 191 | 46627930 |
Cardiac arrest neonatal | 10.34 | 10.33 | 4 | 57937 | 88 | 46628033 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Myocardial infarction | 884.59 | 10.88 | 1140 | 56010 | 124485 | 29770843 |
Chest pain | 435.24 | 10.88 | 793 | 56357 | 116834 | 29778494 |
Coronary artery disease | 405.91 | 10.88 | 487 | 56663 | 49225 | 29846103 |
Angina pectoris | 393.16 | 10.88 | 375 | 56775 | 29143 | 29866185 |
Acute myocardial infarction | 370.39 | 10.88 | 480 | 56670 | 52459 | 29842869 |
Cardiac failure congestive | 316.78 | 10.88 | 573 | 56577 | 83834 | 29811494 |
Injury | 212.73 | 10.88 | 234 | 56916 | 21497 | 29873831 |
Fear | 209.19 | 10.88 | 170 | 56980 | 10655 | 29884673 |
Angina unstable | 208.23 | 10.88 | 179 | 56971 | 12131 | 29883197 |
Coronary arterial stent insertion | 178.55 | 10.88 | 107 | 57043 | 4087 | 29891241 |
Anhedonia | 177.88 | 10.88 | 139 | 57011 | 8230 | 29887098 |
Renal injury | 152.21 | 10.88 | 147 | 57003 | 11582 | 29883746 |
Emotional distress | 146.08 | 10.88 | 165 | 56985 | 15600 | 29879728 |
Drug abuse | 128.04 | 10.88 | 7 | 57143 | 82065 | 29813263 |
Stress | 110.51 | 10.88 | 163 | 56987 | 20072 | 29875256 |
Hypotension | 108.12 | 10.88 | 703 | 56447 | 199862 | 29695466 |
Bradycardia | 103.28 | 10.88 | 317 | 56833 | 65209 | 29830119 |
Product solubility abnormal | 102.65 | 10.88 | 39 | 57111 | 517 | 29894811 |
Unevaluable event | 93.55 | 10.88 | 195 | 56955 | 31590 | 29863738 |
Ischaemic cardiomyopathy | 87.55 | 10.88 | 82 | 57068 | 6215 | 29889113 |
Off label use | 85.82 | 10.88 | 221 | 56929 | 249069 | 29646259 |
Syncope | 85.05 | 10.88 | 354 | 56796 | 84549 | 29810779 |
Toxicity to various agents | 77.68 | 10.88 | 137 | 57013 | 177046 | 29718282 |
Cardiac disorder | 75.36 | 10.88 | 206 | 56944 | 39687 | 29855641 |
Anxiety | 72.20 | 10.88 | 351 | 56799 | 89520 | 29805808 |
Myocardial ischaemia | 71.79 | 10.88 | 123 | 57027 | 17194 | 29878134 |
Dizziness | 70.36 | 10.88 | 622 | 56528 | 194287 | 29701041 |
Coronary artery bypass | 69.43 | 10.88 | 66 | 57084 | 5096 | 29890232 |
Pyrexia | 66.30 | 10.88 | 313 | 56837 | 294176 | 29601152 |
Presyncope | 57.51 | 10.88 | 107 | 57043 | 15949 | 29879379 |
Completed suicide | 57.48 | 10.88 | 63 | 57087 | 99429 | 29795899 |
Neutropenia | 56.63 | 10.88 | 99 | 57051 | 128441 | 29766887 |
Acute coronary syndrome | 55.72 | 10.88 | 96 | 57054 | 13477 | 29881851 |
Coronary artery occlusion | 54.01 | 10.88 | 85 | 57065 | 11072 | 29884256 |
Ventricular extrasystoles | 52.23 | 10.88 | 85 | 57065 | 11389 | 29883939 |
Ventricular fibrillation | 51.88 | 10.88 | 99 | 57051 | 15039 | 29880289 |
Febrile neutropenia | 49.93 | 10.88 | 79 | 57071 | 106614 | 29788714 |
Ventricular tachycardia | 49.90 | 10.88 | 128 | 57022 | 23734 | 29871594 |
Foetal exposure during pregnancy | 49.62 | 10.88 | 6 | 57144 | 36865 | 29858463 |
Cerebrovascular accident | 47.50 | 10.88 | 297 | 56853 | 83180 | 29812148 |
Coronary artery stenosis | 46.56 | 10.88 | 71 | 57079 | 8999 | 29886329 |
Product use in unapproved indication | 45.57 | 10.88 | 44 | 57106 | 73649 | 29821679 |
Atrial fibrillation | 44.73 | 10.88 | 356 | 56794 | 107768 | 29787560 |
Renal failure | 43.59 | 10.88 | 406 | 56744 | 128560 | 29766768 |
Chronic obstructive pulmonary disease | 43.55 | 10.88 | 189 | 56961 | 45937 | 29849391 |
Pain | 40.88 | 10.88 | 506 | 56644 | 172135 | 29723193 |
Dyspnoea | 38.76 | 10.88 | 869 | 56281 | 332426 | 29562902 |
Malignant neoplasm progression | 38.29 | 10.88 | 49 | 57101 | 72238 | 29823090 |
Chest discomfort | 36.73 | 10.88 | 178 | 56972 | 45302 | 29850026 |
Arteriosclerosis coronary artery | 35.75 | 10.88 | 71 | 57079 | 11105 | 29884223 |
Gastrointestinal haemorrhage | 35.17 | 10.88 | 276 | 56874 | 83170 | 29812158 |
C-reactive protein increased | 33.13 | 10.88 | 21 | 57129 | 43452 | 29851876 |
International normalised ratio increased | 31.08 | 10.88 | 176 | 56974 | 47563 | 29847765 |
Prinzmetal angina | 30.24 | 10.88 | 20 | 57130 | 909 | 29894419 |
Diarrhoea | 29.34 | 10.88 | 455 | 56695 | 333648 | 29561680 |
Drug reaction with eosinophilia and systemic symptoms | 29.19 | 10.88 | 9 | 57141 | 28479 | 29866849 |
Therapeutic product effect incomplete | 29.18 | 10.88 | 14 | 57136 | 33820 | 29861508 |
Cardiac failure | 28.85 | 10.88 | 264 | 56886 | 83154 | 29812174 |
Leukopenia | 27.78 | 10.88 | 40 | 57110 | 56119 | 29839209 |
Drug ineffective | 27.74 | 10.88 | 470 | 56680 | 339917 | 29555411 |
Hepatic function abnormal | 27.16 | 10.88 | 24 | 57126 | 41921 | 29853407 |
Cytomegalovirus infection | 27.07 | 10.88 | 6 | 57144 | 23668 | 29871660 |
Troponin increased | 26.82 | 10.88 | 55 | 57095 | 8802 | 29886526 |
Cerebral artery thrombosis | 26.71 | 10.88 | 15 | 57135 | 506 | 29894822 |
Rash | 26.64 | 10.88 | 236 | 56914 | 191653 | 29703675 |
Middle insomnia | 26.59 | 10.88 | 43 | 57107 | 5730 | 29889598 |
Hyperlipidaemia | 25.43 | 10.88 | 71 | 57079 | 13836 | 29881492 |
Base excess decreased | 24.92 | 10.88 | 11 | 57139 | 218 | 29895110 |
Acute kidney injury | 24.62 | 10.88 | 690 | 56460 | 273152 | 29622176 |
Electrocardiogram ST segment elevation | 24.55 | 10.88 | 36 | 57114 | 4406 | 29890922 |
Mucosal inflammation | 24.26 | 10.88 | 14 | 57136 | 30480 | 29864848 |
Orthostatic hypotension | 23.97 | 10.88 | 100 | 57050 | 23879 | 29871449 |
Post procedural complication | 23.58 | 10.88 | 62 | 57088 | 11664 | 29883664 |
Product dose omission issue | 23.19 | 10.88 | 93 | 57057 | 91538 | 29803790 |
Vascular stent occlusion | 22.99 | 10.88 | 9 | 57141 | 130 | 29895198 |
Coronary artery thrombosis | 22.37 | 10.88 | 24 | 57126 | 2140 | 29893188 |
Neutrophil count decreased | 22.24 | 10.88 | 29 | 57121 | 42425 | 29852903 |
Renal impairment | 21.74 | 10.88 | 251 | 56899 | 83933 | 29811395 |
White blood cell count decreased | 21.37 | 10.88 | 85 | 57065 | 83862 | 29811466 |
Brain scan abnormal | 21.12 | 10.88 | 14 | 57136 | 639 | 29894689 |
Neuroleptic malignant syndrome | 21.08 | 10.88 | 3 | 57147 | 16292 | 29879036 |
Infusion related reaction | 20.95 | 10.88 | 28 | 57122 | 40536 | 29854792 |
Oxygen consumption decreased | 20.79 | 10.88 | 9 | 57141 | 170 | 29895158 |
Bone marrow failure | 20.57 | 10.88 | 16 | 57134 | 29769 | 29865559 |
Pulmonary oedema | 20.51 | 10.88 | 149 | 57001 | 43826 | 29851502 |
Arteriosclerosis | 20.50 | 10.88 | 56 | 57094 | 10777 | 29884551 |
Laryngeal haematoma | 20.34 | 10.88 | 8 | 57142 | 117 | 29895211 |
Peripheral vascular disorder | 20.23 | 10.88 | 36 | 57114 | 5183 | 29890145 |
Reperfusion arrhythmia | 20.11 | 10.88 | 7 | 57143 | 71 | 29895257 |
Intentional product misuse | 19.95 | 10.88 | 22 | 57128 | 34645 | 29860683 |
Orthopnoea | 19.81 | 10.88 | 33 | 57117 | 4507 | 29890821 |
Overdose | 19.25 | 10.88 | 89 | 57061 | 84248 | 29811080 |
Rectal haemorrhage | 19.03 | 10.88 | 123 | 57027 | 34816 | 29860512 |
Cardiac arrest | 18.94 | 10.88 | 265 | 56885 | 92585 | 29802743 |
Rheumatoid arthritis | 18.78 | 10.88 | 31 | 57119 | 41166 | 29854162 |
Arteriospasm coronary | 18.67 | 10.88 | 24 | 57126 | 2594 | 29892734 |
Circulatory collapse | 18.44 | 10.88 | 82 | 57068 | 20132 | 29875196 |
Supraventricular tachycardia | 18.35 | 10.88 | 52 | 57098 | 10220 | 29885108 |
Pneumocystis jirovecii pneumonia | 18.29 | 10.88 | 5 | 57145 | 17115 | 29878213 |
International normalised ratio decreased | 18.23 | 10.88 | 32 | 57118 | 4558 | 29890770 |
Post procedural haemorrhage | 18.18 | 10.88 | 44 | 57106 | 7866 | 29887462 |
Blood loss anaemia | 18.15 | 10.88 | 43 | 57107 | 7584 | 29887744 |
Sinus bradycardia | 17.85 | 10.88 | 56 | 57094 | 11639 | 29883689 |
Treatment failure | 17.84 | 10.88 | 24 | 57126 | 34655 | 29860673 |
Infection | 17.46 | 10.88 | 83 | 57067 | 77991 | 29817337 |
Platelet count decreased | 17.25 | 10.88 | 125 | 57025 | 106004 | 29789324 |
Cardiac arrest neonatal | 17.09 | 10.88 | 5 | 57145 | 27 | 29895301 |
Discharge | 17.06 | 10.88 | 7 | 57143 | 115 | 29895213 |
Stomatitis | 17.04 | 10.88 | 28 | 57122 | 37251 | 29858077 |
Non-cardiac chest pain | 16.80 | 10.88 | 29 | 57121 | 4075 | 29891253 |
Carotid artery stenosis | 16.64 | 10.88 | 31 | 57119 | 4623 | 29890705 |
Alanine aminotransferase increased | 16.59 | 10.88 | 79 | 57071 | 74197 | 29821131 |
Vascular graft | 16.58 | 10.88 | 17 | 57133 | 1438 | 29893890 |
Mitral valve incompetence | 16.33 | 10.88 | 59 | 57091 | 13175 | 29882153 |
Atrial flutter | 16.23 | 10.88 | 62 | 57088 | 14219 | 29881109 |
Normochromic normocytic anaemia | 16.19 | 10.88 | 28 | 57122 | 3942 | 29891386 |
Heart rate decreased | 15.41 | 10.88 | 80 | 57070 | 20914 | 29874414 |
Gastrointestinal tract irritation | 15.25 | 10.88 | 8 | 57142 | 235 | 29895093 |
Coagulation time prolonged | 15.13 | 10.88 | 15 | 57135 | 1219 | 29894109 |
Ventricular dysfunction | 15.13 | 10.88 | 26 | 57124 | 3641 | 29891687 |
Death | 15.12 | 10.88 | 544 | 56606 | 356739 | 29538589 |
Vascular graft occlusion | 15.04 | 10.88 | 11 | 57139 | 589 | 29894739 |
Osteonecrosis | 14.98 | 10.88 | 6 | 57144 | 16129 | 29879199 |
Cervicogenic headache | 14.85 | 10.88 | 4 | 57146 | 15 | 29895313 |
Cardiac procedure complication | 14.77 | 10.88 | 8 | 57142 | 251 | 29895077 |
Chronic kidney disease | 14.75 | 10.88 | 123 | 57027 | 37715 | 29857613 |
Nerve degeneration | 14.75 | 10.88 | 7 | 57143 | 165 | 29895163 |
Ecchymosis | 14.69 | 10.88 | 36 | 57114 | 6486 | 29888842 |
Disease progression | 14.51 | 10.88 | 91 | 57059 | 79783 | 29815545 |
Intentional overdose | 14.03 | 10.88 | 37 | 57113 | 41444 | 29853884 |
Sepsis | 13.95 | 10.88 | 196 | 56954 | 146199 | 29749129 |
Decreased appetite | 13.83 | 10.88 | 202 | 56948 | 149708 | 29745620 |
Neurotoxicity | 13.80 | 10.88 | 4 | 57146 | 13178 | 29882150 |
Multiple injuries | 13.69 | 10.88 | 18 | 57132 | 1989 | 29893339 |
Seizure | 13.68 | 10.88 | 121 | 57029 | 98354 | 29796974 |
Arterial spasm | 13.45 | 10.88 | 6 | 57144 | 122 | 29895206 |
Interstitial lung disease | 13.45 | 10.88 | 64 | 57086 | 60133 | 29835195 |
Acute myeloid leukaemia | 13.31 | 10.88 | 9 | 57141 | 17997 | 29877331 |
Stent placement | 13.28 | 10.88 | 28 | 57122 | 4568 | 29890760 |
Swollen tongue | 13.17 | 10.88 | 55 | 57095 | 13137 | 29882191 |
Psychotic disorder | 13.11 | 10.88 | 13 | 57137 | 21502 | 29873826 |
Hyperhidrosis | 13.08 | 10.88 | 190 | 56960 | 66900 | 29828428 |
Poor quality product administered | 13.02 | 10.88 | 16 | 57134 | 1653 | 29893675 |
Left ventricular enlargement | 12.97 | 10.88 | 10 | 57140 | 580 | 29894748 |
Tricuspid valve incompetence | 12.89 | 10.88 | 41 | 57109 | 8582 | 29886746 |
Generalised tonic-clonic seizure | 12.88 | 10.88 | 11 | 57139 | 19540 | 29875788 |
Hypertrophy | 12.86 | 10.88 | 8 | 57142 | 327 | 29895001 |
Hiatus hernia | 12.77 | 10.88 | 36 | 57114 | 7054 | 29888274 |
Hepatocellular injury | 12.73 | 10.88 | 18 | 57132 | 25453 | 29869875 |
Haematuria | 12.62 | 10.88 | 136 | 57014 | 44698 | 29850630 |
Intentional self-injury | 12.62 | 10.88 | 5 | 57145 | 13527 | 29881801 |
Cardiomegaly | 12.59 | 10.88 | 58 | 57092 | 14451 | 29880877 |
Cold sweat | 12.52 | 10.88 | 42 | 57108 | 9040 | 29886288 |
Morning glory syndrome | 12.51 | 10.88 | 3 | 57147 | 6 | 29895322 |
Arrhythmia | 12.50 | 10.88 | 107 | 57043 | 33062 | 29862266 |
Organ failure | 12.46 | 10.88 | 18 | 57132 | 2173 | 29893155 |
Drug resistance | 12.46 | 10.88 | 12 | 57138 | 20121 | 29875207 |
Acute pulmonary oedema | 12.42 | 10.88 | 37 | 57113 | 7478 | 29887850 |
Myocardial necrosis marker increased | 12.23 | 10.88 | 15 | 57135 | 1546 | 29893782 |
Brain natriuretic peptide increased | 12.15 | 10.88 | 25 | 57125 | 4010 | 29891318 |
Ventricular asystole | 12.10 | 10.88 | 6 | 57144 | 156 | 29895172 |
Coronary ostial stenosis | 12.03 | 10.88 | 5 | 57145 | 85 | 29895243 |
Coronary artery restenosis | 12.02 | 10.88 | 13 | 57137 | 1170 | 29894158 |
Mean cell haemoglobin decreased | 11.89 | 10.88 | 13 | 57137 | 1184 | 29894144 |
Melaena | 11.89 | 10.88 | 104 | 57046 | 32333 | 29862995 |
Hyperbilirubinaemia | 11.82 | 10.88 | 9 | 57141 | 16933 | 29878395 |
Palmar-plantar erythrodysaesthesia syndrome | 11.58 | 10.88 | 7 | 57143 | 14863 | 29880465 |
Respiratory arrest | 11.57 | 10.88 | 24 | 57126 | 29234 | 29866094 |
Pneumonia | 11.55 | 10.88 | 521 | 56629 | 333785 | 29561543 |
Ureteral disorder | 11.41 | 10.88 | 6 | 57144 | 177 | 29895151 |
Transaminases increased | 11.31 | 10.88 | 17 | 57133 | 23440 | 29871888 |
Haemorrhage | 11.27 | 10.88 | 136 | 57014 | 45943 | 29849385 |
Blood count abnormal | 11.18 | 10.88 | 48 | 57102 | 11604 | 29883724 |
Ventricular arrhythmia | 11.11 | 10.88 | 25 | 57125 | 4263 | 29891065 |
Injection site pain | 11.06 | 10.88 | 26 | 57124 | 30284 | 29865044 |
Myocardial depression | 11.04 | 10.88 | 4 | 57146 | 46 | 29895282 |
Blood creatine phosphokinase MB increased | 11.02 | 10.88 | 16 | 57134 | 1940 | 29893388 |
Hyperkalaemia | 10.98 | 10.88 | 182 | 56968 | 65828 | 29829500 |
Product complaint | 10.97 | 10.88 | 30 | 57120 | 5776 | 29889552 |
Source | Code | Description |
---|---|---|
ATC | C01DA02 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY VASODILATORS USED IN CARDIAC DISEASES Organic nitrates |
ATC | C01DA52 | CARDIOVASCULAR SYSTEM CARDIAC THERAPY VASODILATORS USED IN CARDIAC DISEASES Organic nitrates |
ATC | C05AE01 | CARDIOVASCULAR SYSTEM VASOPROTECTIVES AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE Muscle relaxants |
FDA CS | M0014874 | Nitrates |
FDA PE | N0000009909 | Vasodilation |
FDA EPC | N0000175415 | Nitrate Vasodilator |
MeSH PA | D002317 | Cardiovascular Agents |
MeSH PA | D053834 | Explosive Agents |
MeSH PA | D014665 | Vasodilator Agents |
CHEBI has role | CHEBI:35620 | vasodilator |
CHEBI has role | CHEBI:35703 | xenobiotic |
CHEBI has role | CHEBI:50266 | prodrugs |
CHEBI has role | CHEBI:50566 | nitric oxide releasing agent |
CHEBI has role | CHEBI:51371 | muscle relaxants |
CHEBI has role | CHEBI:63490 | explosive material |
CHEBI has role | CHEBI:66993 | anti-contraction drug |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Angina pectoris | indication | 194828000 | |
Left ventricular cardiac dysfunction | indication | 429589006 | |
Perioperative hypertension | indication | 434711000124103 | |
Angina Pectoris Prevention | indication | ||
Myocardial infarction | off-label use | 22298006 | DOID:5844 |
Anal fissure | off-label use | 30037006 | |
Decompensated cardiac failure | off-label use | 195111005 | |
Extravasation injury | off-label use | 371100002 | |
Acute coronary syndrome | off-label use | 394659003 | |
Hypertensive urgency | off-label use | 443482000 | |
Hypovolemia | contraindication | 28560003 | |
Cardiac tamponade | contraindication | 35304003 | DOID:115 |
Methemoglobinemia | contraindication | 38959009 | DOID:10783 |
Low blood pressure | contraindication | 45007003 | |
Chronic heart failure | contraindication | 48447003 | |
Injury of head | contraindication | 82271004 | |
Constrictive pericarditis | contraindication | 85598007 | DOID:11481 |
Hypertrophic cardiomyopathy | contraindication | 233873004 | DOID:11984 |
Anemia | contraindication | 271737000 | DOID:2355 |
Cerebral hemorrhage | contraindication | 274100004 | |
Restrictive cardiomyopathy | contraindication | 415295002 | DOID:397 |
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Soluble guanylate cyclase | Enzyme | ACTIVATOR | CHEMBL | CHEMBL | |||||
Atrial natriuretic peptide receptor 1 | Enzyme | WOMBAT-PK |
ID | Source |
---|---|
4017525 | VUID |
N0000145909 | NUI |
D00515 | KEGG_DRUG |
4017525 | VANDF |
C0017887 | UMLSCUI |
CHEBI:28787 | CHEBI |
TNG | PDB_CHEM_ID |
CHEMBL730 | ChEMBL_ID |
DB00727 | DRUGBANK_ID |
D005996 | MESH_DESCRIPTOR_UI |
7053 | IUPHAR_LIGAND_ID |
G59M7S0WS3 | UNII |
4510 | PUBCHEM_CID |
4917 | RXNORM |
2324 | MMSL |
5183 | MMSL |
d00321 | MMSL |
000683 | NDDF |
387404004 | SNOMEDCT_US |
71759000 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Nitrostat | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0417 | TABLET | 0.30 mg | SUBLINGUAL | NDA | 26 sections |
Nitrostat | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0418 | TABLET | 0.40 mg | SUBLINGUAL | NDA | 26 sections |
Nitrostat | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0071-0419 | TABLET | 0.60 mg | SUBLINGUAL | NDA | 26 sections |
Cyclease Menopause | HUMAN OTC DRUG LABEL | 5 | 0220-9082 | TABLET | 4 [hp_C] | ORAL | unapproved homeopathic | 10 sections |
NITRO-BID | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0281-0326 | OINTMENT | 20 mg | TOPICAL | ANDA | 21 sections |
Nitroglycerin In Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1047 | INJECTION | 10 mg | INTRAVENOUS | NDA | 20 sections |
Nitroglycerin In Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1049 | INJECTION | 20 mg | INTRAVENOUS | NDA | 20 sections |
Nitroglycerin In Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1051 | INJECTION | 40 mg | INTRAVENOUS | NDA | 20 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-9102 | PATCH | 0.10 mg | TRANSDERMAL | ANDA | 21 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-9104 | PATCH | 0.20 mg | TRANSDERMAL | ANDA | 21 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-9112 | PATCH | 0.40 mg | TRANSDERMAL | ANDA | 21 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-9116 | PATCH | 0.60 mg | TRANSDERMAL | ANDA | 21 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0517-4810 | INJECTION, SOLUTION | 5 mg | INTRAVENOUS | ANDA | 21 sections |
Nitro-Time | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-0643 | CAPSULE | 2.50 mg | ORAL | Unapproved drug other | 22 sections |
Nitro-Time | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-0644 | CAPSULE | 6.50 mg | ORAL | Unapproved drug other | 22 sections |
Nitro-Time | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-0647 | CAPSULE | 9 mg | ORAL | Unapproved drug other | 22 sections |
Nitroglycerin Transdermal System | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-5495 | PATCH | 0.20 mg | TRANSDERMAL | ANDA | 18 sections |
Nitroglycerin Transdermal System | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-5496 | PATCH | 0.40 mg | TRANSDERMAL | ANDA | 18 sections |
Nitroglycerin Transdermal System | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-5497 | PATCH | 0.60 mg | TRANSDERMAL | ANDA | 18 sections |
Nitrostat | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-450 | TABLET | 0.40 mg | SUBLINGUAL | NDA | 23 sections |
Nitroglycerin Slocaps | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-635 | CAPSULE | 2.50 mg | ORAL | Unapproved drug other | 19 sections |
Nitroglycerin Slocaps | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-636 | CAPSULE | 6.50 mg | ORAL | Unapproved drug other | 19 sections |
Nitroglycerin | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-810 | TABLET | 0.40 mg | ORAL | Unapproved drug other | 23 sections |
NITROGLYCERIN LINGUAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 28595-120 | SPRAY | 400 ug | ORAL | NDA | 26 sections |
NITROLINGUAL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 28595-550 | SPRAY | 400 ug | ORAL | NDA | 26 sections |
GONITRO | HUMAN PRESCRIPTION DRUG LABEL | 1 | 28595-705 | POWDER | 400 ug | SUBLINGUAL | NDA | 26 sections |
Minitran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29336-301 | PATCH | 2.50 mg | TRANSDERMAL | ANDA | 21 sections |
Minitran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29336-302 | PATCH | 5 mg | TRANSDERMAL | ANDA | 21 sections |
Minitran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29336-303 | PATCH | 10 mg | TRANSDERMAL | ANDA | 21 sections |
Minitran | HUMAN PRESCRIPTION DRUG LABEL | 1 | 29336-304 | PATCH | 15 mg | TRANSDERMAL | ANDA | 21 sections |