glyceryl trinitrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
NO2 - derivatives 1952 55-63-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nitroglycerin
  • nitroglycerine
  • nitroglycerol
  • propanetriol trinitrate
  • trinitroglycerin
  • trinitroglycerol
  • glyceryl trinitrate
A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
  • Molecular weight: 227.09
  • Formula: C3H5N3O9
  • CLOGP: 0.92
  • LIPINSKI: 1
  • HAC: 12
  • HDO: 0
  • TPSA: 165.15
  • ALOGS: -3.05
  • ROTB: 8
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
5 mg O
2.50 mg oral aerosol
2.50 mg SL
5 mg TD

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

glyceryl trinitrate