trichloroethylene Indications/Contra | FAERs | Orange Book | BioActivity |

Stem definitionDrug idCAS RN
3628 79-01-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • trichloroethylene
  • ethylene trichloride
  • 1,1,2-Trichloroethylene
  • chlorilen
  • trichloroethene
A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.
  • Molecular weight: 131.38
  • Formula: C2HCl3
  • CLOGP: 2.63
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -1.83
  • ROTB: 0

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

SourceCodeDescription
ATC N01AB05 NERVOUS SYSTEM
ANESTHETICS
ANESTHETICS, GENERAL
Halogenated hydrocarbons
CHEBI has role CHEBI:38870 inhalation anaesthetic
MeSH PA D000777 Anesthetics
MeSH PA D018681 Anesthetics, General
MeSH PA D018685 Anesthetics, Inhalation
MeSH PA D002491 Central Nervous System Agents
MeSH PA D002492 Central Nervous System Depressants
MeSH PA D012997 Solvents

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:16602 CHEBI
CHEMBL279816 ChEMBL_ID
290YE8AR51 UNII
2131 INN_ID
16808006 SNOMEDCT_US
333887003 SNOMEDCT_US
NOCODE MMSL
N0000166328 NDFRT
001395 NDDF
D014241 MESH_DESCRIPTOR_UI
DB13323 DRUGBANK_ID
6575 PUBCHEM_CID

Pharmaceutical products:

None