chloroform indications/contra

Stem definitionDrug idCAS RN
4363 67-66-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chloroform
  • trichloroform
  • trichloromethane
A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.
  • Molecular weight: 119.37
  • Formula: CHCl3
  • CLOGP: 1.95
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -1.23
  • ROTB: 0

Drug dosage:

None

Approvals:

None

FDA Adverse Event Reporting System

None

Pharmacologic Action:

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SourceCodeDescription
ATC N01AB02 NERVOUS SYSTEM
ANESTHETICS
ANESTHETICS, GENERAL
Halogenated hydrocarbons
MeSH PA D012997 Solvents
CHEBI has role CHEBI:78433 refrigerant
CHEBI has role CHEBI:35470 central nervous system drug
CHEBI has role CHEBI:38870 inhalation anaesthetic

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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IDSource
4025221 VUID
N0000171757 NUI
C0008238 UMLSCUI
7V31YC746X UNII
CHEMBL44618 ChEMBL_ID
D002725 MESH_DESCRIPTOR_UI
NOCODE MMSL
4025221 VANDF
424273005 SNOMEDCT_US
N0000171757 NDFRT
N0000166326 NDFRT
1362698 RXNORM
001343 NDDF
001396 NDDF
259153006 SNOMEDCT_US
6212 PUBCHEM_CID
CHEBI:35255 CHEBI

Pharmaceutical products:

None