DNA gyrase subunit B

Description:

Description
  • Accession: P0A4L9
  • Swissprot: GYRB_STRPN
  • Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
  • Gene: gyrB
  • Target class: Enzyme

Drug Relations:

gatifloxacin
A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS. Bioactivity details MOA
grepafloxacin
Bioactivity details MOA
levofloxacin
The L-isomer of Ofloxacin. Bioactivity details MOA
novobiocin
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Bioactivity details MOA