novobiocin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, produced by Streptomyces strains 1974 303-81-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • novobiocin
  • albamycin
  • cardelmycin
  • cathomycin
  • inamycin
  • streptonivicin
  • novobiocin calcium
  • novobiocin sodium
  • novobiocin sodium salt
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
  • Molecular weight: 612.63
  • Formula: C31H36N2O11
  • CLOGP: 3.98
  • LIPINSKI: 2
  • HAC: 13
  • HDO: 5
  • TPSA: 196.10
  • ALOGS: -4.80
  • ROTB: 9

Drug dosage:

None

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

🐶 Veterinary products

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

novobiocin