OTHER SAFETY INFORMATION.

ANTIDOTE. In case of accidental poisoning, follow these directions:External:Eye Exposure -- First: Wash out the eye with lukewarm water for at least fifteen (15) minutes then call your physician or go to your nearest Emergency Room. Skin Exposure -- First: Wash the area very thoroughly with soap and water then call your physician. Internal:First: Give one (1) glass of milk or water then call your physician or go to your nearest Emergency Room.

ADVERSE REACTIONS SECTION.

HAZARDS. Long continued applications to large areas may produce argyria, slate-blue discoloration of the skin and mucous membranes.

DESCRIPTION SECTION.

for Simplified Silver Nitrate TherapyARZOL Silver Nitrate Applicators provide simple and convenient means of treating small lesions of the skin and mucous membranes. On contact with living tissue, silver nitrate acts as an escharotic. Deep action is avoided by the formation of dense surface film of coagulated albumin. Silver nitrate is powerful chemical germicide. Despite precipitation, it retains substantial germicidal potency even in the presence of large quantities of albuminous material, possibly by gradually redissolving the silver.

DOSAGE & ADMINISTRATION SECTION.

APPLICATION. ARZOL may be applied direct to mucous membranes and other moist surfaces. In the case of dry skin, the applicator tip should be dipped in water immediately before use. Apply carefully to the area to be treated. DO NOT USE ON THE EYES.

DOSAGE FORMS & STRENGTHS SECTION.

Silver Nitrate 75%Potassium Nitrate 25%.

GENERAL PRECAUTIONS SECTION.

SPECIAL PROPERTIES. The combination of silver nitrate with potassium nitrate has been called toughened silver nitrate, also lunar caustic. When the tip of the applicator is impregnated with this compound, as in ARZOL, the silver nitrate can be applied quickly and conveniently to the precise area to be treated without spread of the escharotic to adjacent healthy tissues. Exposure to light causes the silver in the tip to oxidize and turn brown in color. This discoloration does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water.Moisture has deteriorating effect on the tip. It may cause it to break or loosen from the applicator; therefore the applicators should be kept in dry place.CAUTION: Silver Nitrate is caustic compound, the improper use of which may cause chemical burns. Silver Nitrate mixes with body fluids; this mixture is caustic and tissue damage may result if not removed quickly. Contact of Silver Nitrate applicators on neonates (as in use on the umbilicus) and on thin delicate skin should be extremely short in duration.

HOW SUPPLIED SECTION.

AVAILABILITY. ARZOL Silver Nitrate Applicators are supplied in boxes of 100 containing 10 packets each with 10 applicators; also, in plastic tubes containing 100 applicators.

INDICATIONS & USAGE SECTION.

INDICATIONS. On the skin, applications of silver nitrate are recommended for cauterization of wounds and sluggish ulcers, also for removal of granulation tissue and warts. On mucous membranes, silver nitrate may be applied to small ulcers and aphthae in the mouth resulting from injury or stomatitis, to infected tonsils, to rectal fissures and fistulae, and to vaginal or cervical ulcerations or erosions. Epistaxis may be controlled by direct application to the site of hemorrhage within the nostrils.

INSTRUCTIONS FOR USE SECTION.

Arzol Insert Front. Arzol Insert Back. ARZOL(R) Silver Nitrate Applicators. Silver Nitrate 75%Potassium Nitrate 25%. for Simplified Silver Nitrate TherapyARZOL Silver Nitrate Applicators provide simple and convenient means of treating small lesions of the skin and mucous membranes. On contact with living tissue, silver nitrate acts as an escharotic. Deep action is avoided by the formation of dense surface film of coagulated albumin. Silver nitrate is powerful chemical germicide. Despite precipitation, it retains substantial germicidal potency even in the presence of large quantities of albuminous material, possibly by gradually redissolving the silver.. SPECIAL PROPERTIES. The combination of silver nitrate with potassium nitrate has been called toughened silver nitrate, also lunar caustic. When the tip of the applicator is impregnated with this compound, as in ARZOL, the silver nitrate can be applied quickly and conveniently to the precise area to be treated without spread of the escharotic to adjacent healthy tissues. Exposure to light causes the silver in the tip to oxidize and turn brown in color. This discoloration does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water.Moisture has deteriorating effect on the tip. It may cause it to break or loosen from the applicator; therefore the applicators should be kept in dry place.CAUTION: Silver Nitrate is caustic compound, the improper use of which may cause chemical burns. Silver Nitrate mixes with body fluids; this mixture is caustic and tissue damage may result if not removed quickly. Contact of Silver Nitrate applicators on neonates (as in use on the umbilicus) and on thin delicate skin should be extremely short in duration. INDICATIONS. On the skin, applications of silver nitrate are recommended for cauterization of wounds and sluggish ulcers, also for removal of granulation tissue and warts. On mucous membranes, silver nitrate may be applied to small ulcers and aphthae in the mouth resulting from injury or stomatitis, to infected tonsils, to rectal fissures and fistulae, and to vaginal or cervical ulcerations or erosions. Epistaxis may be controlled by direct application to the site of hemorrhage within the nostrils. APPLICATION. ARZOL may be applied direct to mucous membranes and other moist surfaces. In the case of dry skin, the applicator tip should be dipped in water immediately before use. Apply carefully to the area to be treated. DO NOT USE ON THE EYES.. SIDE EFFECTS. Silver nitrate blackens the tissues to which it is applied but this discoloration gradually disappears. In the case of applicators, poisoning from ingestion is rare.. ANTIDOTE. In case of accidental poisoning, follow these directions:External:Eye Exposure -- First: Wash out the eye with lukewarm water for at least fifteen (15) minutes then call your physician or go to your nearest Emergency Room. Skin Exposure -- First: Wash the area very thoroughly with soap and water then call your physician. Internal:First: Give one (1) glass of milk or water then call your physician or go to your nearest Emergency Room. HAZARDS. Long continued applications to large areas may produce argyria, slate-blue discoloration of the skin and mucous membranes.. AVAILABILITY. ARZOL Silver Nitrate Applicators are supplied in boxes of 100 containing 10 packets each with 10 applicators; also, in plastic tubes containing 100 applicators.

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL.

Arzol Box Packaging. Arzol(R) Silver Nitrate Applicators. Silver Nitrate 75%Potassium Nitrate 25%. FOR SIMPLIFIED SILVER NITRATE THERAPY. POISON. CAUTION:Federal law prohibits dispensing without prescription. Do not open this box or dispense packets or applicators separately.. WARNING:Keep out of reach of children. Keep in dry and dark place. Do not use on the eyes.. 100 APPLICATORS. ANTIDOTE. In case of accidental poisoning, follow these directions.EXTERNAL -EYE EXPOSURE:FIRST: Wash out the eye with lukewarm water for at least fifteen (15) minutes THEN: call your physician or go to your nearest Emergency Room. SKIN EXPOSURE:FIRST: Wash the areas very thoroughly with soap and water THEN: call your physician. INTERNAL:FIRST: Give one (1) glass of milk or water THEN: call your physician or go to your nearest Emergency Room. STABILITY PRECAUTIONS. Light causes the silver in the tip to oxidize and turn brown in color. This does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water.Moisture has deteriorating effect on the tip. It will cause the tip to break or loosen from the applicator; therefore the applicators should be kept in dry and dark place.

STATEMENT OF IDENTITY SECTION.

ARZOL(R) Silver Nitrate Applicators.

STORAGE AND HANDLING SECTION.

STABILITY PRECAUTIONS. Light causes the silver in the tip to oxidize and turn brown in color. This does not affect the therapeutic action of the tip and the oxidized film readily dissolves when dipped in water.Moisture has deteriorating effect on the tip. It will cause the tip to break or loosen from the applicator; therefore the applicators should be kept in dry and dark place.

WARNINGS AND PRECAUTIONS SECTION.

WARNING:Keep out of reach of children. Keep in dry and dark place. Do not use on the eyes.

WARNINGS SECTION.

SIDE EFFECTS. Silver nitrate blackens the tissues to which it is applied but this discoloration gradually disappears. In the case of applicators, poisoning from ingestion is rare.