efloxate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
991 119-41-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • efloxate
  • flacethyle
  • oxiflavil
  • oxyflavil
  • Molecular weight: 324.33
  • Formula: C19H16O5
  • CLOGP: 3.73
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 0
  • TPSA: 61.83
  • ALOGS: -4.62
  • ROTB: 6

Drug dosage:

DoseUnitRoute
0.20 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,CHEK1,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,MAP3K1,MAP3K21,MAP3K7,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CD,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ULK1 53
kinase-selectivity-class ACVR2A,ACVR2B,AXL,BRAF,CAMK2D,CDK9,DDR1,DYRK1B,ERBB2,GRK2,MAP2K6,MAPK7,PRKDC,SIK2,STK33,TTK 16
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C01DX13 CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
VASODILATORS USED IN CARDIAC DISEASES
Other vasodilators used in cardiac diseases
CHEBI has role CHEBI:35554 cardiovascular drug

Related Drugs by ATC class:

C01DX Other vasodilators used in cardiac diseases 18 drugs
benziodaronecarbocromencinepazetcloridaroldilazepetafenoneheptaminolhexobendineimolamineitramin tosilatelinsidominemolsidomine show all 18 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01135 KEGG_DRUG
C0058961 UMLSCUI
CHEBI:31531 CHEBI
CHEMBL1349073 ChEMBL_ID
DB13333 DRUGBANK_ID
C005472 MESH_SUPPLEMENTAL_RECORD_UI
8395 PUBCHEM_CID
1452 INN_ID
CZU6V3902K UNII
23852 RXNORM
005411 NDDF

Pharmaceutical products:

None