cinepazet 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
650 23887-41-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • cinepazet maleate
  • acoridil
  • cinepazet hydrochloride
  • cinepazet HCl
  • ethyl cinepazate maleate
  • cinepazet
  • ethyl cinepazate
  • Molecular weight: 392.45
  • Formula: C20H28N2O6
  • CLOGP: 2.16
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 0
  • TPSA: 77.54
  • ALOGS: -3.08
  • ROTB: 9

Drug dosage:

DoseUnitRoute
0.90 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,GRK2,ITK,JAK2,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK2,PAK4,PDK2,PDK4,PDPK1,PIK3CB,PIM2,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK 39
kinase-selectivity-class ACVR2B,AXL,DDR1,EPHB4,ERBB2,GRK2,IRAK3,JAK1,MAP3K21,MAPK7,PDK4,PRKDC,SIK2 13
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C01DX14 CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
VASODILATORS USED IN CARDIAC DISEASES
Other vasodilators used in cardiac diseases
CHEBI has role CHEBI:35554 cardiovascular drug

Related Drugs by ATC class:

C01DX Other vasodilators used in cardiac diseases 18 drugs
benziodaronecarbocromencloridaroldilazepefloxateetafenoneheptaminolhexobendineimolamineitramin tosilatelinsidominemolsidomine show all 18 →

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.16 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
50679-07-7 SECONDARY_CAS_RN
C0055739 UMLSCUI
CHEBI:135617 CHEBI
CHEMBL2110784 ChEMBL_ID
CHEMBL2106028 ChEMBL_ID
DB13342 DRUGBANK_ID
C020997 MESH_SUPPLEMENTAL_RECORD_UI
6434395 PUBCHEM_CID
3677 INN_ID
0LC95WWE9Q UNII
C2983978 UMLSCUI
CHEMBL2104437 ChEMBL_ID
54063-23-9 SECONDARY_CAS_RN
6443799 PUBCHEM_CID
3137 INN_ID
OX0J88C7UX UNII
CHEBI:750832 CHEBI

Pharmaceutical products:

None