disopyramide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
class I antiarrhythmics, disopyramide derivatives 926 3737-09-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • disopyramide
  • dicorantil
  • disopyramide phosphate
  • disopyramide tartrate
  • disopyramide monohydrochloride
  • disopyramide hydrochloride
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
  • Molecular weight: 339.48
  • Formula: C21H29N3O
  • CLOGP: 2.58
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 1
  • TPSA: 59.22
  • ALOGS: -3.84
  • ROTB: 8
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
0.40 g O
0.40 g P

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

disopyramide