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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
prajmalium 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
antiarrhythmics, ajmaline derivatives
2230
35080-11-6
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
prajmaline bitartrate
prajmaline
prajmalium
N4-Propylajmalinium
N-Propylajmalinium
N-Propylajmaline
A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.
Molecular weight: 369.53
Formula: C23H33N2O2
CLOGP: -0.37
LIPINSKI: 0
HAC: 4
HDO: 2
TPSA: 43.70
ALOGS: -4.13
ROTB: 3
Drug dosage:
Dose
Unit
Route
30
mg
O
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
C01BA08
CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
ANTIARRHYTHMICS, CLASS I AND III
Antiarrhythmics, class Ia
MeSH PA
D000889
Anti-Arrhythmia Agents
MeSH PA
D002317
Cardiovascular Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Ventricular arrhythmia
indication
44103008
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
7.57
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
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ID
Source
007115
NDDF
007116
NDDF
236896
RXNORM
75934UD4GJ
UNII
76959818
PUBCHEM_CID
C0032899
UMLSCUI
CHEBI:135560
CHEBI
CHEMBL3833382
ChEMBL_ID
CHEMBL3833388
ChEMBL_ID
D011219
MESH_DESCRIPTOR_UI
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Pharmaceutical products:
None
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prajmalium