prajmalium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiarrhythmics, ajmaline derivatives 2230 35080-11-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prajmaline bitartrate
  • prajmaline
  • prajmalium
  • N4-Propylajmalinium
  • N-Propylajmalinium
  • N-Propylajmaline
A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.
  • Molecular weight: 369.53
  • Formula: C23H33N2O2
  • CLOGP: -0.37
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 43.70
  • ALOGS: -4.13
  • ROTB: 3

Drug dosage:

DoseUnitRoute
30 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C01BA08 CARDIOVASCULAR SYSTEM
CARDIAC THERAPY
ANTIARRHYTHMICS, CLASS I AND III
Antiarrhythmics, class Ia
MeSH PA D000889 Anti-Arrhythmia Agents
MeSH PA D002317 Cardiovascular Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Ventricular arrhythmia indication 44103008




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.57 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0032899 UMLSCUI
CHEBI:135560 CHEBI
CHEMBL3833382 ChEMBL_ID
CHEMBL3833388 ChEMBL_ID
DB13555 DRUGBANK_ID
76959818 PUBCHEM_CID
75934UD4GJ UNII
236896 RXNORM
007115 NDDF
007116 NDDF
D011219 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None