clometocillin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 699 1926-49-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • clometocillin
  • clometacillin
  • clomethacillin
  • clomethocillin
  • clometicillin
  • DL-Clometocillin
  • Molecular weight: 433.30
  • Formula: C17H18Cl2N2O5S
  • CLOGP: 3.23
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 2
  • TPSA: 95.94
  • ALOGS: -4.19
  • ROTB: 5

Drug dosage:

DoseUnitRoute
1 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,ERBB2,GRK2,GSK3B,ITK,JAK2,JAK3,MAP2K6,MAP3K21,MAP3K7,MAPK7,MAPK9,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PRKDC,SIK2,STK33,SYK,TEK,TGFBR1,ZAP70 41
kinase-selectivity-class AXL,BRAF,EIF2AK3,GRK2,MAP2K6,TEK 6
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01CE07 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Beta-lactamase sensitive penicillins
CHEBI has role CHEBI:33282 antibacterial agent
CHEBI has role CHEBI:36047 antibacterial drug

Related Drugs by ATC class:

J01CE Beta-lactamase sensitive penicillins 9 drugs
azidocillinbenzathine benzylpenicillinbenzathine phenoxymethylpenicillinbenzylpenicillinpenamecillinpheneticillinphenoxymethylpenicillinprocaine benzylpenicillinpropicillin

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07236 KEGG_DRUG
C0055921 UMLSCUI
CHEBI:131732 CHEBI
CHEMBL2106548 ChEMBL_ID
DB13686 DRUGBANK_ID
71807 PUBCHEM_CID
12294 IUPHAR_LIGAND_ID
C010434 MESH_SUPPLEMENTAL_RECORD_UI
1326 INN_ID
YI8LL014GF UNII
713466003 SNOMEDCT_US

Pharmaceutical products:

None