ceftezole 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, cefalosporanic acid derivatives 561 26973-24-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ceftezole
  • ceftezol
  • ceftezole sodium
  • demethylcefazolin
  • demethyl cefazolin
  • Molecular weight: 440.47
  • Formula: C13H12N8O4S3
  • CLOGP: -1.08
  • LIPINSKI: 1
  • HAC: 12
  • HDO: 2
  • TPSA: 156.09
  • ALOGS: -2.71
  • ROTB: 7

Drug dosage:

DoseUnitRoute
3 g P

ADMET properties:

PropertyValueReference
CL (Clearance) 5.37 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 0.64 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01DB12 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER BETA-LACTAM ANTIBACTERIALS
First-generation cephalosporins
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.07 acidic
pKa2 12.21 acidic
pKa3 1.13 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07656 KEGG_DRUG
C0055013 UMLSCUI
CHEBI:135716 CHEBI
CHEMBL1697829 ChEMBL_ID
DB13821 DRUGBANK_ID
C012811 MESH_SUPPLEMENTAL_RECORD_UI
12259 IUPHAR_LIGAND_ID
3914 INN_ID
41136-22-5 SECONDARY_CAS_RN
2Z86SYP11W UNII
65755 PUBCHEM_CID
010924 NDDF
010925 NDDF

Pharmaceutical products:

None