lutropin alfa 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4929	152923-57-4

Description:

Molecule

Description

Synonyms:

luteinising hormone
lutropin alfa
luveris
lutropin alfa for injection
lutropina alfa
r-hLH
human LH

Molecular weight:
Formula:
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
75	U	P

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Oct. 8, 2004	FDA	EMD SERONO

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Ovarian hyperstimulation syndrome	493.42	115.31	69	281	3945	63484727

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Ovarian hyperstimulation syndrome	509.27	104.74	68	279	3503	79740538

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	G03GA07	GENITO URINARY SYSTEM AND SEX HORMONES SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM GONADOTROPINS AND OTHER OVULATION STIMULANTS Gonadotropins
FDA CS	M0009540	Gonadotropins
FDA EPC	N0000175838	Gonadotropin

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Lutropin-choriogonadotropic hormone receptor	GPCR	P22888	LSHR_HUMAN	AGONIST	IC50	10.90		IUPHAR	DRUG LABEL

External reference:

ID	Source
D04824	KEGG_DRUG
4021497	VUID
N0000148867	NUI
4019252	VANDF
4021497	VANDF
CHEMBL1201419	ChEMBL_ID
DB00044	DRUGBANK_ID
DB14741	DRUGBANK_ID
388084	RXNORM
18123	MMSL
52532	MMSL
d05029	MMSL
009355	NDDF
391621007	SNOMEDCT_US
415248001	SNOMEDCT_US
64182005	SNOMEDCT_US
C1271607	UMLSCUI
CHEMBL1201697	ChEMBL_ID
7047	INN_ID
3JGY52XJNA	UNII

Pharmaceutical products:

None