chorionic gonadotrophin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5196 9002-61-3

Description:

MoleculeDescription

Synonyms:

  • chorionic gonadotropin
  • chorionic gonadotrophin
  • gonadotropin, chorionic
  • choriogonadotropin
  • human chorionic gonadotropin
  • serum gonadotropin
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
  • Molecular weight:
  • Formula:
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
250 U P

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA FERRING

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Ovarian hyperstimulation syndrome 501.72 70.72 72 359 3942 63484649
Adnexal torsion 70.97 70.72 10 421 444 63488147

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Ovarian hyperstimulation syndrome 459.38 68.47 62 278 3509 79740539

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC G03GA01 GENITO URINARY SYSTEM AND SEX HORMONES
SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
GONADOTROPINS AND OTHER OVULATION STIMULANTS
Gonadotropins
MeSH PA D012102 Reproductive Control Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypogonadotropic hypogonadism indication 33927004
Induction of ovulation and pregnancy indication 61285001
Prepubertal cryptorchidism indication 204878001 DOID:11383
Controlled ovarian stimulation indication 732970000
Induction of final follicular maturation and luteinization indication
Carcinoma of prostate contraindication 254900004 DOID:10286
Precocious puberty contraindication 400179000
Androgendependent neoplasm contraindication




🐶 Veterinary Drug Use

SpeciesUseRelation
Cattle Nymphomania caused by cystic ovaries Indication
Fish Improving spawning function in male and female brood finfish Indication
Swine Estrus induction Indication
Swine Estrus induction Indication

🐶 Veterinary products

ProductApplicantIngredients
Follutein Veterinary Zoetis Inc. 1
P.G. 600 Intervet Inc. 2
P.G. 600 Intervet Inc. 2
Chorulon Intervet Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017617 VANDF
4017618 VANDF
C0018062 UMLSCUI
CHEMBL1201509 ChEMBL_ID
DB09126 DRUGBANK_ID
D06457 KEGG_DRUG
4330 MMSL
4798 MMSL
8572 MMSL
d00572 MMSL
001254 NDDF
20577002 SNOMEDCT_US
408755005 SNOMEDCT_US
412126005 SNOMEDCT_US
59433001 SNOMEDCT_US
D006063 MESH_DESCRIPTOR_UI
1972 INN_ID
177073-44-8 SECONDARY_CAS_RN
340705 RXNORM
20ED16GHEB UNII

Pharmaceutical products:

None