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| Stem definition | Drug id | CAS RN |
|---|---|---|
| 5196 | 9002-61-3 |
| Molecule | Description |
|---|---|
|
Synonyms:
|
A gonadotropic glycoprotein hormone produced primarily by the PLACENTA. Similar to the pituitary LUTEINIZING HORMONE in structure and function, chorionic gonadotropin is involved in maintaining the CORPUS LUTEUM during pregnancy. CG consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is virtually identical to the alpha subunits of the three pituitary glycoprotein hormones (TSH, LH, and FSH), but the beta subunit is unique and confers its biological specificity (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN).
|
| Dose | Unit | Route |
|---|---|---|
| 250 | U | P |
None
None
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | FERRING |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Ovarian hyperstimulation syndrome | 570.29 | 60.24 | 83 | 449 | 5779 | 90622136 |
| Adnexal torsion | 70.78 | 60.24 | 10 | 522 | 524 | 90627391 |
None
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Ovarian hyperstimulation syndrome | 537.54 | 64.60 | 74 | 357 | 5286 | 110583582 |
None
| Source | Code | Description |
|---|---|---|
| ATC | G03GA01 | GENITO URINARY SYSTEM AND SEX HORMONES SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM GONADOTROPINS AND OTHER OVULATION STIMULANTS Gonadotropins |
| MeSH PA | D012102 | Reproductive Control Agents |
| CHEBI has role | CHEBI:35610 | antineoplastic agent |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Hypogonadotropic hypogonadism | indication | 33927004 | |
| Induction of ovulation and pregnancy | indication | 61285001 | |
| Prepubertal cryptorchidism | indication | 204878001 | DOID:11383 |
| Controlled ovarian stimulation | indication | 732970000 | |
| Induction of final follicular maturation and luteinization | indication | ||
| Carcinoma of prostate | contraindication | 254900004 | DOID:10286 |
| Precocious puberty | contraindication | 400179000 | |
| Androgendependent neoplasm | contraindication |
| Species | Use | Relation |
|---|---|---|
| Cattle | Nymphomania caused by cystic ovaries | Indication |
| Fish | Improving spawning function in male and female brood finfish | Indication |
| Swine | Estrus induction | Indication |
| Swine | Estrus induction | Indication |
| Product | Applicant | Ingredients |
|---|---|---|
| Follutein Veterinary | Zoetis Inc. | 1 |
| P.G. 600 | Intervet Inc. | 2 |
| P.G. 600 | Intervet Inc. | 2 |
| Chorulon | Intervet Inc. | 1 |
None
None
None
None
| ID | Source |
|---|---|
| 4017617 | VANDF |
| 4017618 | VANDF |
| C0018062 | UMLSCUI |
| CHEBI:749576 | CHEBI |
| CHEMBL1201509 | ChEMBL_ID |
| 4369448 | PUBCHEM_CID |
| DB09126 | DRUGBANK_ID |
| D06457 | KEGG_DRUG |
| 20577002 | SNOMEDCT_US |
| 408755005 | SNOMEDCT_US |
| 412126005 | SNOMEDCT_US |
| 59433001 | SNOMEDCT_US |
| D006063 | MESH_DESCRIPTOR_UI |
| 1972 | INN_ID |
| 177073-44-8 | SECONDARY_CAS_RN |
| 4330 | MMSL |
| 4798 | MMSL |
| 8572 | MMSL |
| d00572 | MMSL |
| 001254 | NDDF |
| 20ED16GHEB | UNII |
| 340705 | RXNORM |
None