ornipressin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| vasopressin analogues | 4679 | 3397-23-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A synthetic analog of vasopressin with ORNITHINE substitution at residue 8 of the cyclic nonapeptide. It is used as a local vasoconstrictor and hemostatic.
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 5 | U | P |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | H01BA05 | SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES POSTERIOR PITUITARY LOBE HORMONES Vasopressin and analogues |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D003029 | Coagulants |
| MeSH PA | D006401 | Hematologic Agents |
| MeSH PA | D006490 | Hemostatics |
| MeSH PA | D014662 | Vasoconstrictor Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.47 | acidic |
| pKa2 | 12.33 | acidic |
| pKa3 | 12.66 | acidic |
| pKa4 | 12.81 | acidic |
| pKa5 | 13.19 | acidic |
| pKa6 | 13.28 | acidic |
| pKa7 | 13.55 | acidic |
| pKa8 | 13.68 | acidic |
| pKa9 | 10.12 | Basic |
| pKa10 | 6.4 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07227 | KEGG_DRUG |
| N0000170338 | NUI |
| CHEBI:136020 | CHEBI |
| CHEMBL1819440 | ChEMBL_ID |
| 2544 | INN_ID |
| DB13464 | DRUGBANK_ID |
| 1KTH6N080W | UNII |
| 7703 | RXNORM |
| 006913 | NDDF |
| 703839000 | SNOMEDCT_US |
| C0029276 | UMLSCUI |
| D009951 | MESH_DESCRIPTOR_UI |
| 14257660 | PUBCHEM_CID |
Pharmaceutical products:
None