calcium citrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4479 7693-13-2

Description:

MoleculeDescription

Synonyms:

  • calcium citrate
A colorless crystalline or white powdery organic, tricarboxylic acid occurring in plants, especially citrus fruits, and used as a flavoring agent, as an antioxidant in foods, and as a sequestrating agent. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
  • Molecular weight: 498.43
  • Formula: C12H10Ca3O14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 140.62
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Recalled product 182.73 16.75 40 5790 1295 50597999
Hypocalcaemia 76.11 16.75 44 5786 26772 50572522
Gouty tophus 52.74 16.75 10 5820 154 50599140
Muscle spasms 29.12 16.75 52 5778 125501 50473793
Osteomalacia 20.18 16.75 6 5824 666 50598628
Diarrhoea 18.94 16.75 124 5706 588352 50010942
Fatigue 17.53 16.75 140 5690 707461 49891833

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Polyomavirus-associated nephropathy 37.96 22.58 12 1645 3384 29569486
Fatigue 26.54 22.58 56 1601 316765 29256105

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Recalled product 63.30 17.55 15 5717 904 64492096
Gouty tophus 48 17.55 10 5722 332 64492668
Hypocalcaemia 32.35 17.55 28 5704 41725 64451275
Fatigue 30.40 17.55 139 5593 748591 63744409
Polyomavirus-associated nephropathy 28.27 17.55 12 5720 4876 64488124
Fall 19.59 17.55 81 5651 416745 64076255

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA13 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium
MeSH PA D005503 Food Additives

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Diarrhea contraindication 62315008
Blood coagulation disorder contraindication 64779008 DOID:1247
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Vitamin K Deficiency Induced Hypoprothrombinemia contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00933 KEGG_DRUG
4019484 VUID
N0000147604 NUI
4019479 VANDF
4019484 VANDF
CHEMBL2106123 ChEMBL_ID
DB11093 DRUGBANK_ID
MLM29U2X85 UNII
13136 PUBCHEM_CID
47613 RXNORM
16535 MMSL
4334 MMSL
6782 MMSL
d03866 MMSL
003645 NDDF
D019355 MESH_DESCRIPTOR_UI
C0108101 UMLSCUI
5785-44-4 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CitraNatal Harmony 3.0 HUMAN PRESCRIPTION DRUG LABEL 8 0178-0796 CAPSULE, GELATIN COATED 104 mg ORAL unapproved drug other 10 sections
Citranatal Harmony 2.1 HUMAN PRESCRIPTION DRUG LABEL 2 0178-0797 CAPSULE, GELATIN COATED 104 mg ORAL unapproved drug other 10 sections
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0798 CAPSULE, GELATIN COATED 104 mg ORAL UNAPPROVED DRUG OTHER 11 sections
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0799 CAPSULE, GELATIN COATED 100 mg ORAL Unapproved drug other 11 sections
CitraNatal Harmony HUMAN PRESCRIPTION DRUG LABEL 8 0178-0812 CAPSULE, GELATIN COATED 100 mg ORAL Unapproved drug other 11 sections
CitraNatal 90 DHA HUMAN PRESCRIPTION DRUG LABEL 16 0178-0821 TABLET 159 mg ORAL unapproved drug other 11 sections
CitraNatal 90 DHA HUMAN OTC DRUG LABEL 14 0178-0829 TABLET 160 mg ORAL Unapproved drug other 11 sections
CitraNatal Rx HUMAN PRESCRIPTION DRUG LABEL 13 0178-0858 TABLET 124 mg ORAL Unapproved drug other 12 sections
CitraNatal Rx HUMAN PRESCRIPTION DRUG LABEL 14 0178-0859 TABLET 125 mg ORAL Unapproved drug other 9 sections
CitraNatal Medley HUMAN PRESCRIPTION DRUG LABEL 8 0178-0896 CAPSULE, GELATIN COATED 62 mg ORAL unapproved drug other 10 sections
CitraNatal DHA HUMAN OTC DRUG LABEL 14 0178-0898 TABLET 125 mg ORAL Unapproved drug other 11 sections
Prenaissance Plus HUMAN PRESCRIPTION DRUG LABEL 8 42192-343 CAPSULE, LIQUID FILLED 100 mg ORAL UNAPPROVED DRUG OTHER 10 sections
Dairy Allergen Mix HUMAN OTC DRUG LABEL 38 43742-1277 LIQUID 6 [hp_C] ORAL unapproved drug other 9 sections
INATAL Ultra HUMAN PRESCRIPTION DRUG LABEL 16 63044-154 TABLET, COATED 200 mg ORAL Unapproved drug other 10 sections