iodine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4446 7553-56-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iodine
A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
  • Molecular weight: 253.81
  • Formula: I2
  • CLOGP:
  • LIPINSKI: None
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS:
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 2843.03 66.60 551 182 46092 2311260

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Drug hypersensitivity 496.88 38.99 106 195 15029 1731451
Dehydration 43.46 38.99 17 284 17641 1728839

Pharmacologic Action:

SourceCodeDescription
ATC D08AG01 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Iodine products
ATC D08AG03 DERMATOLOGICALS
ANTISEPTICS AND DISINFECTANTS
ANTISEPTICS AND DISINFECTANTS
Iodine products
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000891 Anti-Infective Agents, Local
MeSH PA D018977 Micronutrients
MeSH PA D014131 Trace Elements

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Provision of therapeutic radionuclide indication 74385000
CD20 Positive Non-Hodgkin's Lymphoma indication
Neonatal thyrotoxicosis off-label use 13795004 DOID:12573
Thyrotoxic crisis off-label use 29028009 DOID:12837
Hyperthyroidism off-label use 34486009 DOID:7998
Lymphocutaneous sporotrichosis off-label use 87603003
Iodine deficiency off-label use 238121000
Thyroid Surgery off-label use
Thyroid Gland Radiation Protection off-label use
Bacterial septicemia contraindication 10001005 DOID:0040085
Hashimoto thyroiditis contraindication 21983002
Shock contraindication 27942005
Bronchitis contraindication 32398004 DOID:6132
Hypothyroidism contraindication 40930008 DOID:1459
Decreased respiratory function contraindication 80954004
Kidney disease contraindication 90708001 DOID:557
Open wound contraindication 125643001
Seizure disorder contraindication 128613002
Pulmonary tuberculosis contraindication 154283005 DOID:2957
Heart block contraindication 233916004
Disease of liver contraindication 235856003 DOID:409
Hypocomplementemic urticarial vasculitis contraindication 239945009
Pregnancy, function contraindication 289908002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Neutropenic disorder contraindication 303011007 DOID:1227
Breastfeeding (mother) contraindication 413712001
Denuded skin contraindication 418242004
Human Anti-Mouse Antibody (HAMA) Positive contraindication
Severe Bone Marrow Depression contraindication

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D007455 MESH_DESCRIPTOR_UI
D00108 KEGG_DRUG
4017659 VUID
N0000146037 NUI
C0021968 UMLSCUI
9679TC07X4 UNII
DB05382 DRUGBANK_ID
CHEBI:24859 CHEBI
CHEMBL1201225 ChEMBL_ID
807 PUBCHEM_CID
767115003 SNOMEDCT_US
5933 RXNORM
44588005 SNOMEDCT_US
4900 MMSL
4017659 VANDF
d05776 MMSL
000852 NDDF
003150 NDDF
007599 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CitraNatal Assure HUMAN PRESCRIPTION DRUG LABEL 13 0178-0891 KIT 150 ug None unapproved drug other 12 sections
CitraNatal Assure HUMAN PRESCRIPTION DRUG LABEL 14 0178-0893 KIT 150 ug None Unapproved drug other 12 sections
Iodine Tincture Mild HUMAN OTC DRUG LABEL 2 0395-1213 LIQUID 20 mg TOPICAL OTC monograph not final 9 sections
Humco Strong Iodine Tincture HUMAN OTC DRUG LABEL 3 0395-1219 LIQUID 70 mg TOPICAL OTC monograph not final 12 sections
Humco Strong Iodine HUMAN PRESCRIPTION DRUG LABEL 2 0395-2775 LIQUID 50 mg ORAL unapproved drug other 12 sections
Iodine Tincture Mild HUMAN OTC DRUG LABEL 2 0395-9118 LIQUID 20 mg TOPICAL OTC monograph not final 9 sections
Vitafol HUMAN PRESCRIPTION DRUG LABEL 11 0642-0070 CAPSULE, GELATIN COATED 0.15 mg ORAL unapproved drug other 6 sections
Vitafol HUMAN PRESCRIPTION DRUG LABEL 12 0642-0092 CAPSULE, LIQUID FILLED 200 ug ORAL UNAPPROVED DRUG OTHER 10 sections
Vitafol HUMAN PRESCRIPTION DRUG LABEL 7 0642-0094 TABLET, COATED 150 ug ORAL UNAPPROVED DRUG OTHER 10 sections
Vitafol Fe Plus HUMAN PRESCRIPTION DRUG LABEL 12 0642-0096 KIT 150 ug None UNAPPROVED DRUG OTHER 10 sections
Reaphirm Plant Source DHA HUMAN PRESCRIPTION DRUG LABEL 11 0642-3010 CAPSULE, GELATIN COATED 0.15 mg ORAL unapproved drug other 6 sections
O-Cal Prenatal Vitamin HUMAN PRESCRIPTION DRUG LABEL 12 0813-0202 TABLET 150 ug ORAL UNAPPROVED DRUG OTHER 6 sections
Iodine HUMAN OTC DRUG LABEL 2 0869-0088 LIQUID 20 mg TOPICAL OTC monograph not final 12 sections
LUGOLS SOLUTION HUMAN PRESCRIPTION DRUG LABEL 1 10481-0111 LIQUID 0.40 g TOPICAL unapproved drug other 4 sections
Iodine HUMAN OTC DRUG LABEL 2 11344-088 LIQUID 20 mg TOPICAL OTC monograph not final 12 sections
IODINE HUMAN OTC DRUG LABEL 2 16638-166 SOLUTION 0.50 g TOPICAL OTC monograph not final 8 sections
De La Cruz Tincture of Iodine HUMAN OTC DRUG LABEL 2 24286-1528 LIQUID 20 mg TOPICAL OTC monograph not final 10 sections
GNP Idoinde Tincture 2% Mild HUMAN OTC DRUG LABEL 2 24385-213 LIQUID 20 mg TOPICAL OTC monograph not final 14 sections
Iodine Tincture HUMAN OTC DRUG LABEL 1 30142-088 SOLUTION/ DROPS 20 mg TOPICAL OTC monograph not final 13 sections
LEADER Mild Iodine HUMAN OTC DRUG LABEL 2 37205-022 TINCTURE 2 mg TOPICAL OTC monograph not final 11 sections
Iodine HUMAN OTC DRUG LABEL 2 41163-088 LIQUID 20 mg TOPICAL OTC monograph not final 12 sections
Bal-Care DHA HUMAN PRESCRIPTION DRUG LABEL 16 42546-180 KIT 0.22 mg None unapproved drug other 4 sections
Bal-Care DHA Essential HUMAN PRESCRIPTION DRUG LABEL 16 42546-185 KIT 0.22 mg None unapproved drug other 4 sections
Moms Choice Rx HUMAN PRESCRIPTION DRUG LABEL 14 42546-190 KIT 0.22 mg None unapproved drug other 5 sections
Duet DHA Balanced HUMAN PRESCRIPTION DRUG LABEL 14 44118-750 KIT 210 ug None unapproved drug other 10 sections
Duet DHA HUMAN PRESCRIPTION DRUG LABEL 14 44118-807 KIT 220 ug ORAL unapproved drug other 10 sections
Sunmark Iodine HUMAN OTC DRUG LABEL 2 49348-133 TINCTURE 20 mg TOPICAL OTC monograph not final 7 sections
Iodine HUMAN OTC DRUG LABEL 2 50804-088 LIQUID 20 mg TOPICAL OTC monograph not final 12 sections
DDM Iodine Tincture Mild HUMAN OTC DRUG LABEL 2 53943-213 LIQUID 20 mg TOPICAL OTC monograph not final 9 sections
Leep RediKit HUMAN PRESCRIPTION DRUG LABEL 4 59365-6061 KIT 0.05 g None UNAPPROVED DRUG OTHER 16 sections