dexchlorpheniramine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4411	25523-97-1

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: dexchlorpheniramine (+)-Chloropheniramine (+)-Chlorpheniramine S-Chlorpheniramine d-Chlorpheniramine dexchlorpheniramine maleate	Molecular weight: 274.79 Formula: C16H19ClN2 CLOGP: 3.15 LIPINSKI: 0 HAC: 2 HDO: 0 TPSA: 16.13 ALOGS: -3.72 ROTB: 5 Status: OFP Legend: OFP - off patent OFM - off market ONP - on patent

Molecule

Description

Molfile Inchi Smiles

Synonyms:

dexchlorpheniramine
(+)-Chloropheniramine
(+)-Chlorpheniramine
S-Chlorpheniramine
d-Chlorpheniramine
dexchlorpheniramine maleate

Molecular weight: 274.79
Formula: C16H19ClN2
CLOGP: 3.15
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 16.13
ALOGS: -3.72
ROTB: 5

Status: OFP

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

Dose	Unit	Route
6	mg	O
6	mg	P

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
July 14, 1981	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Erythema	353.31	26.60	232	7208	155707	56128920
Infusion related reaction	207.81	26.60	191	7249	208740	56075887
Hepatocellular injury	152.49	26.60	73	7367	26441	56258186
Hypersensitivity	142.58	26.60	172	7268	256236	56028391
Anaphylactic shock	134.64	26.60	63	7377	21677	56262950
Cytokine release syndrome	101.29	26.60	42	7398	10833	56273794
Sense of oppression	91.20	26.60	22	7418	955	56283672
Pyrexia	89.88	26.60	181	7259	418592	55866035
Febrile neutropenia	84.73	26.60	86	7354	105459	56179168
Oxygen saturation decreased	77.67	26.60	72	7368	78995	56205632
Rash maculo-papular	62.60	26.60	42	7398	28865	56255762
Dyspnoea	59.37	26.60	192	7248	592385	55692242
Hyperthermia	57.49	26.60	26	7414	8259	56276368
Fatigue	56.91	26.60	17	7423	788535	55496092
Neutrophil count decreased	56.05	26.60	49	7391	49773	56234854
Drug ineffective	56.00	26.60	26	7414	918963	55365664
Lymphopenia	53.05	26.60	31	7409	16743	56267884
Chest discomfort	50.93	26.60	64	7376	98793	56185834
Febrile bone marrow aplasia	46.79	26.60	21	7419	6551	56278076
Hypertension	45.65	26.60	100	7340	244178	56040449
Bronchospasm	44.44	26.60	27	7413	15642	56268985
Hypotension	41.74	26.60	98	7342	250410	56034217
Chills	39.98	26.60	58	7382	102546	56182081
Feeling hot	38.96	26.60	37	7403	41750	56242877
Hepatic function abnormal	38.88	26.60	34	7406	34524	56250103
Cholestasis	37.57	26.60	30	7410	26883	56257744
Wrong patient received product	36.87	26.60	13	7427	2158	56282469
Pruritus	36.54	26.60	108	7332	316515	55968112
Urticaria	36.29	26.60	67	7373	144609	56140018
Tachycardia	35.77	26.60	56	7384	105820	56178807
Pain	35.53	26.60	22	7418	663162	55621465
Platelet count decreased	34.19	26.60	55	7385	106328	56178299
Neutropenia	32.09	26.60	67	7373	158100	56126527
Hypothermia	31.59	26.60	20	7420	12450	56272177
Malaise	31.20	26.60	113	7327	367747	55916880
Serum sickness	30.80	26.60	12	7428	2630	56281997
Psychiatric decompensation	30.53	26.60	10	7430	1328	56283299
Cytomegalovirus infection	27.98	26.60	22	7418	19274	56265353
Persecutory delusion	27.60	26.60	11	7429	2559	56282068
Anaphylactoid reaction	27.52	26.60	12	7428	3494	56281133
Drug reaction with eosinophilia and systemic symptoms	26.67	26.60	26	7414	30278	56254349

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Cytokine release syndrome	181.90	23.25	85	7288	16557	31673414
Infusion related reaction	141.98	23.25	105	7268	47950	31642021
Febrile bone marrow aplasia	137.76	23.25	56	7317	7790	31682181
Erythema	133.85	23.25	126	7247	80279	31609692
Hypersensitivity	119.83	23.25	101	7272	55642	31634329
Febrile neutropenia	114.43	23.25	141	7232	121708	31568263
Pyrexia	87.40	23.25	207	7166	303633	31386338
Anaphylactic shock	73.51	23.25	44	7329	14101	31675870
Alveolar lung disease	72.38	23.25	17	7356	366	31689605
Pulmonary interstitial emphysema syndrome	68.78	23.25	17	7356	457	31689514
Generalised oedema	65.60	23.25	38	7335	11463	31678508
Neutropenia	64.19	23.25	116	7257	140248	31549723
Hyperthermia	54.26	23.25	32	7341	9972	31679999
Chills	49.78	23.25	73	7300	74077	31615894
Diffuse alveolar damage	47.28	23.25	18	7355	2101	31687870
Fatigue	43.81	23.25	12	7361	335194	31354777
Face oedema	42.51	23.25	28	7345	10588	31679383
Hyperammonaemia	40.68	23.25	22	7351	5811	31684160
Kounis syndrome	40.45	23.25	16	7357	2068	31687903
Sense of oppression	38.74	23.25	11	7362	509	31689462
Necrotising retinitis	37.95	23.25	12	7361	805	31689166
Eosinophilic pneumonia	37.48	23.25	17	7356	3080	31686891
Interstitial lung disease	34.91	23.25	56	7317	61347	31628624
Cytomegalovirus test positive	32.03	23.25	16	7357	3589	31686382
Cardiac ventricular disorder	31.49	23.25	8	7365	241	31689730
Rash	30.99	23.25	110	7263	201376	31488595
Platelet count decreased	30.14	23.25	74	7299	110361	31579610
Disseminated intravascular coagulation	29.94	23.25	30	7343	20507	31669464
Drug ineffective	29.80	23.25	29	7344	395544	31294427
Oxygen saturation decreased	29.58	23.25	46	7327	49069	31640902
Abdominal compartment syndrome	29.34	23.25	10	7363	849	31689122
Hypotension	28.34	23.25	108	7265	204510	31485461
Malaise	27.62	23.25	94	7279	168417	31521554
Neutrophil count decreased	27.31	23.25	43	7330	46351	31643620
Acute coronary syndrome	27.04	23.25	23	7350	12766	31677205
Hypoxia	26.05	23.25	44	7329	50269	31639702
Hepatic encephalopathy	25.72	23.25	23	7350	13648	31676323
Blood immunoglobulin G decreased	25.48	23.25	10	7363	1265	31688706
Cytomegalovirus infection	25.36	23.25	30	7343	24677	31665294
Tumour lysis syndrome	25.28	23.25	24	7349	15361	31674610
Drug interaction	24.45	23.25	9	7364	208534	31481437
Urticaria	24.26	23.25	46	7327	57471	31632500
Eosinophilia	23.48	23.25	28	7345	23225	31666746
Bronchospasm	23.30	23.25	19	7354	9953	31680018

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Erythema	437.86	19.60	350	14551	199213	70714330
Infusion related reaction	331.22	19.60	297	14604	197237	70716306
Cytokine release syndrome	267.01	19.60	124	14777	26343	70887200
Hypersensitivity	234.37	19.60	264	14637	229548	70683995
Anaphylactic shock	180.97	19.60	102	14799	32388	70881155
Febrile neutropenia	173.71	19.60	214	14687	204104	70709439
Pyrexia	154.76	19.60	371	14530	606581	70306962
Febrile bone marrow aplasia	148.93	19.60	65	14836	11926	70901617
Hepatocellular injury	136.46	19.60	97	14804	45994	70867549
Sense of oppression	121.06	19.60	33	14868	1457	70912086
Hyperthermia	102.82	19.60	56	14845	16615	70896928
Fatigue	93.06	19.60	29	14872	824290	70089253
Oxygen saturation decreased	87.74	19.60	115	14786	116314	70797229
Chills	86.68	19.60	128	14773	144658	70768885
Neutropenia	86.39	19.60	176	14725	256980	70656563
Neutrophil count decreased	76.48	19.60	91	14810	83465	70830078
Rash maculo-papular	74.65	19.60	71	14830	50474	70863069
Pulmonary interstitial emphysema syndrome	70.63	19.60	17	14884	453	70913090
Drug ineffective	70.28	19.60	57	14844	939695	69973848
Alveolar lung disease	67.79	19.60	17	14884	539	70913004
Toxicity to various agents	67.63	19.60	3	14898	382169	70531374
Platelet count decreased	64.61	19.60	126	14775	178096	70735447
Hepatic function abnormal	57.24	19.60	71	14830	67925	70845618
Hypotension	56.64	19.60	200	14701	404181	70509362
Hypertension	53.71	19.60	160	14741	295873	70617670
Interstitial lung disease	53.40	19.60	86	14815	104599	70808944
Bronchospasm	51.88	19.60	41	14860	22751	70890792
Dyspnoea	50.23	19.60	304	14597	769756	70143787
Pain	49.61	19.60	36	14865	628780	70284763
Urticaria	49.31	19.60	107	14794	162942	70750601
Generalised oedema	49.30	19.60	39	14862	21669	70891874
Feeling hot	47.83	19.60	55	14846	48615	70864928
Face oedema	47.65	19.60	41	14860	25598	70887945
Malaise	47.37	19.60	198	14703	432734	70480809
Pruritus	46.71	19.60	169	14732	345391	70568152
Tumour lysis syndrome	45.58	19.60	37	14864	21323	70892220
White blood cell count decreased	45.14	19.60	106	14795	170035	70743508
Cytomegalovirus infection	44.34	19.60	48	14853	39710	70873833
Thrombocytopenia	43.11	19.60	129	14772	238981	70674562
Diffuse alveolar damage	41.00	19.60	18	14883	3345	70910198
Hyperammonaemia	40.84	19.60	26	14875	10267	70903276
Lymphopenia	39.56	19.60	38	14863	27321	70886222
Cytomegalovirus test positive	38.17	19.60	20	14881	5488	70908055
Serum sickness	37.89	19.60	17	14884	3324	70910219
Kounis syndrome	37.56	19.60	17	14884	3394	70910149
Enterocolitis	37.49	19.60	27	14874	13039	70900504
Septic shock	36.61	19.60	76	14825	112182	70801361
Disseminated intravascular coagulation	36.48	19.60	40	14861	33558	70879985
Hypothermia	36.38	19.60	32	14869	20562	70892981
Hypoxia	35.01	19.60	67	14834	93277	70820266
Chest discomfort	34.63	19.60	79	14822	124302	70789241
Necrotising retinitis	34.50	19.60	12	14889	1199	70912344
Arthralgia	34.50	19.60	33	14868	503357	70410186
Anaphylactoid reaction	34.18	19.60	18	14883	4989	70908554
Tachycardia	33.88	19.60	91	14810	158455	70755088
Rash	32.79	19.60	201	14700	510361	70403182
Upper respiratory tract inflammation	32.21	19.60	16	14885	3926	70909617
Anaphylactic reaction	32.12	19.60	57	14844	74917	70838626
Product dose omission issue	32.00	19.60	4	14897	217464	70696079
Eosinophilic pneumonia	31.69	19.60	17	14884	4888	70908655
Drug intolerance	31.23	19.60	5	14896	225682	70687861
Pain in extremity	31.15	19.60	15	14886	328067	70585476
Acute coronary syndrome	31.15	19.60	29	14872	20050	70893493
Cardiac ventricular disorder	29.61	19.60	8	14893	341	70913202
Condition aggravated	29.33	19.60	28	14873	427607	70485936
Dizziness	28.90	19.60	33	14868	464108	70449435
Lung disorder	28.71	19.60	52	14849	69432	70844111
Sepsis	27.57	19.60	113	14788	244432	70669111
Abdominal discomfort	27.05	19.60	6	14895	214652	70698891
Swelling	26.48	19.60	4	14897	188535	70725008
Weight increased	26.37	19.60	9	14892	242322	70671221
Eosinophilia	26.05	19.60	37	14864	40282	70873261
Oropharyngeal discomfort	25.73	19.60	16	14885	6063	70907480
Hepatitis	25.38	19.60	41	14860	49939	70863604
Abdominal compartment syndrome	25.23	19.60	10	14891	1439	70912104
Hyperamylasaemia	24.82	19.60	9	14892	1015	70912528
Off label use	24.14	19.60	250	14651	742810	70170733
Cyanosis	24.11	19.60	27	14874	23179	70890364
Drug reaction with eosinophilia and systemic symptoms	23.43	19.60	43	14858	57970	70855573
Sinusitis	22.84	19.60	4	14897	169191	70744352
Cholestasis	22.60	19.60	38	14863	47834	70865709
Mucosal inflammation	22.18	19.60	46	14855	67804	70845739
Wrong patient received product	22.08	19.60	13	14888	4467	70909076
Hepatic encephalopathy	21.73	19.60	25	14876	22093	70891450
Type I hypersensitivity	21.53	19.60	12	14889	3720	70909823
Larynx irritation	21.12	19.60	5	14896	124	70913419
Aspartate aminotransferase increased	20.52	19.60	66	14835	126912	70786631
Erythema multiforme	20.24	19.60	21	14880	16543	70897000
Therapeutic product effect decreased	20.16	19.60	3	14898	143015	70770528

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	R06AB02	RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Substituted alkylamines
ATC	R06AB52	RESPIRATORY SYSTEM ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE Substituted alkylamines
MeSH PA	D018494	Histamine Agents
MeSH PA	D006633	Histamine Antagonists
MeSH PA	D006634	Histamine H1 Antagonists
MeSH PA	D018377	Neurotransmitter Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Dermatographic urticaria	indication	7632005	DOID:743
Vasomotor rhinitis	indication	8229003	DOID:4730
Allergic rhinitis	indication	61582004
Urticaria	indication	126485001
Seasonal allergic rhinitis	indication	367498001
Itching of skin	indication	418363000
Allergic conjunctivitis	indication	473460002	DOID:11204
Brain damage	contraindication	2470005
Ocular hypertension	contraindication	4210003	DOID:9282
Tachyarrhythmia	contraindication	6285003
Suicidal thoughts	contraindication	6471006
Dependent drug abuse	contraindication	6525002
Urinary tract obstruction	contraindication	7163005	DOID:5200
Alcoholism	contraindication	7200002
Alcohol withdrawal delirium	contraindication	8635005
Peptic ulcer	contraindication	13200003	DOID:750
Asthenia	contraindication	13791008
Severe chronic ulcerative colitis	contraindication	14311001
Constipation	contraindication	14760008	DOID:2089
Chronic disease of respiratory system	contraindication	17097001
Mood swings	contraindication	18963009
Myocardial infarction	contraindication	22298006	DOID:5844
Inflammatory bowel disease	contraindication	24526004	DOID:0050589
Ventricular tachycardia	contraindication	25569003
Alcohol intoxication	contraindication	25702006
Shock	contraindication	27942005
Toxic megacolon	contraindication	28536002	DOID:1770
Atony of colon	contraindication	29479008
Hypercapnia	contraindication	29596007
Dehydration	contraindication	34095006
Hyperthyroidism	contraindication	34486009	DOID:7998
Acute hepatitis	contraindication	37871000
Hypertensive disorder	contraindication	38341003	DOID:10763
Disorder of gallbladder	contraindication	39621005	DOID:0060262
Hypothyroidism	contraindication	40930008	DOID:1459
Complete trisomy 21 syndrome	contraindication	41040004	DOID:14250
Conduction disorder of the heart	contraindication	44808001
Low blood pressure	contraindication	45007003
Achalasia of esophagus	contraindication	45564002	DOID:9164
Chronic heart failure	contraindication	48447003
Bradycardia	contraindication	48867003
Disorder of cardiovascular system	contraindication	49601007	DOID:1287
Acidosis	contraindication	51387008
Coronary arteriosclerosis	contraindication	53741008	DOID:3393
Paralytic ileus	contraindication	55525008	DOID:8442
Peptic reflux disease	contraindication	57643001
Hepatic failure	contraindication	59927004
Ulcerative colitis	contraindication	64766004	DOID:8577
Arterial thrombosis	contraindication	65198009
Drug AND/OR toxin-induced diarrhea	contraindication	65979008
Substance abuse	contraindication	66214007
Benign intracranial hypertension	contraindication	68267002	DOID:11459
Poisoning by acetaminophen	contraindication	70273001
Arteriosclerotic vascular disease	contraindication	72092001
Diabetes mellitus	contraindication	73211009	DOID:9351
Urethral stricture	contraindication	76618002
Spastic paralysis	contraindication	78403003
Disturbance of salivary secretion	contraindication	78948009
Decreased respiratory function	contraindication	80954004
Injury of head	contraindication	82271004
Chronic idiopathic constipation	contraindication	82934008
Cor pulmonale	contraindication	83291003	DOID:8515
Hiatal hernia	contraindication	84089009	DOID:12642
Epilepsy	contraindication	84757009	DOID:1826
Pulmonary emphysema	contraindication	87433001
Kidney disease	contraindication	90708001	DOID:557
Myasthenia gravis	contraindication	91637004	DOID:437
Acute abdominal pain	contraindication	116290004
Procedure on urinary system	contraindication	118677009
Gastrointestinal obstruction	contraindication	126765001
Neoplasm of brain	contraindication	126952004	DOID:1319
Seizure disorder	contraindication	128613002
Autonomic dysreflexia	contraindication	129618003
Bleeding	contraindication	131148009
Drug-induced psychosis	contraindication	191483003	DOID:1742
Partial atrioventricular block	contraindication	195039008
Acute pancreatitis	contraindication	197456007	DOID:2913
Myocardial dysfunction	contraindication	233928007
Disease of liver	contraindication	235856003	DOID:409
Bladder outflow obstruction	contraindication	236645006
Morbid obesity	contraindication	238136002	DOID:11981
Pyloric obstruction	contraindication	244815007
Benign prostatic hyperplasia	contraindication	266569009
Retention of urine	contraindication	267064002
Drowsy	contraindication	271782001
Exacerbation of asthma	contraindication	281239006
Lesion of brain	contraindication	301766008
Coma	contraindication	371632003
Primary adrenocortical insufficiency	contraindication	373662000
Operation on gastrointestinal tract	contraindication	386621005
Hypoxia	contraindication	389086002
Angle-closure glaucoma	contraindication	392291006	DOID:13550
Pseudomembranous enterocolitis	contraindication	397683000
Gastric ulcer	contraindication	397825006	DOID:10808
Breastfeeding (mother)	contraindication	413712001
Chronic lung disease	contraindication	413839001
Disorder of coronary artery	contraindication	414024009
Central nervous system depression	contraindication	418072004
Ultrarapid metabolizer due to cytochrome p450 CYP2D6 variant	contraindication	422681000
Dysfunction of sphincter of Oddi	contraindication	430887001
Hypertensive urgency	contraindication	443482000
Acute exacerbation of asthma	contraindication	708038006

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.47	Basic
pKa2	4.14	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Bioact source	MoA source
Histamine H1 receptor	GPCR	P35367	HRH1_HUMAN	ANTAGONIST	Ki	9.14	CHEMBL	CHEMBL
Sigma non-opioid intracellular receptor 1	Membrane receptor	Q99720	SGMR1_HUMAN		Ki	6.16	DRUG MATRIX
Sodium-dependent serotonin transporter	Transporter	P31645	SC6A4_HUMAN		Ki	7.89	DRUG MATRIX
Sodium-dependent noradrenaline transporter	Transporter	P23975	SC6A2_HUMAN		Ki	5.31	DRUG MATRIX
5-hydroxytryptamine receptor 2A	GPCR	P28223	5HT2A_HUMAN		Ki	5.98	DRUG MATRIX
5-hydroxytryptamine receptor 2C	GPCR	P28335	5HT2C_HUMAN		Ki	5.92	DRUG MATRIX
Alpha-2B adrenergic receptor	GPCR	P18089	ADA2B_HUMAN		Ki	5.68	DRUG MATRIX
Histamine H2 receptor	GPCR	P25021	HRH2_HUMAN		Ki	5.09	DRUG MATRIX
Muscarinic acetylcholine receptor M1	GPCR	P11229	ACM1_HUMAN		Ki	6.48	DRUG MATRIX
Muscarinic acetylcholine receptor M2	GPCR	P08172	ACM2_HUMAN		Ki	5.60	DRUG MATRIX
Muscarinic acetylcholine receptor M3	GPCR	P20309	ACM3_HUMAN		Ki	6.26	DRUG MATRIX
Muscarinic acetylcholine receptor M4	GPCR	P08173	ACM4_HUMAN		Ki	6.56	DRUG MATRIX
Muscarinic acetylcholine receptor M5	GPCR	P08912	ACM5_HUMAN		Ki	6.13	DRUG MATRIX
Sodium-dependent dopamine transporter	Transporter	Q01959	SC6A3_HUMAN		Ki	6.13	DRUG MATRIX
Alpha-1D adrenergic receptor	GPCR	P25100	ADA1D_HUMAN		Ki	4.78	DRUG MATRIX
Alpha-2A adrenergic receptor	GPCR	P08913	ADA2A_HUMAN		Ki	5.12	DRUG MATRIX
Alpha-1B adrenergic receptor	GPCR		ADA1B_RAT		Ki	5.07	DRUG MATRIX
Membrane-associated progesterone receptor component 1	Membrane receptor		PGRC1_RAT		Ki	4.93	DRUG MATRIX

External reference:

ID	Source
D07803	KEGG_DRUG
4019712	VUID
N0000147804	NUI
2438-32-6	SECONDARY_CAS_RN
4018792	VANDF
4019712	VANDF
C0057606	UMLSCUI
CHEBI:4464	CHEBI
CHEMBL1201353	ChEMBL_ID
CHEMBL1200927	ChEMBL_ID
DB13679	DRUGBANK_ID
C018904	MESH_SUPPLEMENTAL_RECORD_UI
1210	IUPHAR_LIGAND_ID
955	INN_ID
3Q9Q0B929N	UNII
33036	PUBCHEM_CID
DB09555	DRUGBANK_ID
22697	RXNORM
1479	MMSL
4556	MMSL
d00784	MMSL
003393	NDDF
004796	NDDF
16031005	SNOMEDCT_US
372663001	SNOMEDCT_US
68680008	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
RYMED	HUMAN OTC DRUG LABEL	2	0485-0080	TABLET, COATED	2 mg	ORAL	OTC monograph final	16 sections
RYCLORA	HUMAN PRESCRIPTION DRUG LABEL	1	15370-150	LIQUID	2 mg	ORAL	ANDA	13 sections
Polytussin DM	HUMAN OTC DRUG LABEL	3	50991-492	SYRUP	1 mg	ORAL	OTC monograph final	13 sections
ABATUSS DMX	HUMAN OTC DRUG LABEL	3	52083-625	LIQUID	1 mg	ORAL	OTC monograph final	10 sections
ABATUSS DMX	HUMAN OTC DRUG LABEL	3	52083-625	LIQUID	1 mg	ORAL	OTC monograph final	10 sections
DELTUSS DMX Cough Suppressant Nasal Decongestant Antihistamine GRAPE Flavor	HUMAN OTC DRUG LABEL	3	58238-225	LIQUID	1 mg	ORAL	OTC monograph final	16 sections
DELTUSS DP Nasal Decongestant Antihistamine CHERRY Flavor	HUMAN OTC DRUG LABEL	2	58238-226	LIQUID	1 mg	ORAL	OTC monograph final	16 sections
VANACOF	HUMAN OTC DRUG LABEL	3	58809-999	LIQUID	1 mg	ORAL	OTC monograph final	16 sections
Rescon	HUMAN OTC DRUG LABEL	2	64543-097	TABLET, MULTILAYER	2 mg	ORAL	OTC monograph final	15 sections
POLMON	HUMAN PRESCRIPTION DRUG LABEL	1	64543-600	SOLUTION	2 mg	ORAL	ANDA	14 sections
Dexchlorpheniramine Maleate, Phenylephrine HCl	HUMAN OTC DRUG LABEL	2	66576-080	TABLET	2 mg	ORAL	OTC monograph final	8 sections
PRO-REDAC	HUMAN OTC DRUG LABEL	3	66594-499	SYRUP	1 mg	ORAL	OTC monograph final	16 sections
chlophedianol hydrochloride, dexchlorpheniramine maleate, and pseudoephedrine hydrochloride	HUMAN OTC DRUG LABEL	3	69367-183	LIQUID	1 mg	ORAL	OTC MONOGRAPH FINAL	17 sections
WesTussin DM	HUMAN OTC DRUG LABEL	3	69367-334	SYRUP	1 mg	ORAL	OTC MONOGRAPH FINAL	17 sections