All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

ferrous fumarate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4261	141-01-5

Description:

Molecule	Description
Synonyms: ferrous fumarate iron fumarate	used in treatment of iron deficiency anemia; RN given refers to Fe(+2)[1:1] salt Molecular weight: 169.90 Formula: C4H2FeO4 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
0.20	g	O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

Date	Agency	Company	Orphan
July 18, 1986	FDA	GD SEARLE LLC

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Swelling face	217	10.58	277	63601	81075	90483494
Swollen tongue	213.30	10.58	209	63669	45747	90518822
Hand deformity	178.44	10.58	7	63871	296355	90268214
Glossodynia	174.17	10.58	14	63864	321765	90242804
Dysphonia	165.38	10.58	213	63665	62871	90501698
Pericarditis	160.55	10.58	7	63871	270144	90294425
Fall	151.35	10.58	706	63172	481104	90083465
Angioedema	141.04	10.58	200	63678	64676	90499893
Systemic lupus erythematosus	137.67	10.58	42	63836	361854	90202715
Helicobacter infection	131.18	10.58	7	63871	226843	90337726
Infusion related reaction	129.62	10.58	66	63812	416714	90147855
Folliculitis	125.85	10.58	4	63874	204349	90360220
Wound	122.99	10.58	31	63847	302949	90261620
Haematocrit decreased	118.76	10.58	147	63731	41685	90522884
Haemoglobin decreased	115.16	10.58	311	63567	161645	90402924
Red blood cell count decreased	112.94	10.58	151	63727	46200	90518369
Irritable bowel syndrome	88.57	10.58	19	63859	207429	90357140
Drug ineffective for unapproved indication	86.88	10.58	163	63715	66481	90498088
General physical health deterioration	86.37	10.58	74	63804	355041	90209528
Product use issue	86.19	10.58	64	63814	329855	90234714
Red blood cell sedimentation rate abnormal	83.52	10.58	94	63784	24110	90540459
Liver injury	83.01	10.58	11	63867	170556	90394013
Blister	82.84	10.58	38	63840	254960	90309609
Multiple fractures	82.35	10.58	62	63816	9500	90555069
Rheumatoid factor positive	81.35	10.58	12	63866	171638	90392931
Sleep disorder due to general medical condition, insomnia type	77.54	10.58	3	63875	128691	90435878
Hepatic enzyme increased	77.45	10.58	84	63794	360652	90203917
Type 2 diabetes mellitus	74.72	10.58	25	63853	203219	90361350
Maternal exposure during pregnancy	73.86	10.58	87	63791	359976	90204593
Discomfort	73.23	10.58	52	63826	274283	90290286
Diarrhoea	66.07	10.58	977	62901	938213	89626356
Ill-defined disorder	65.80	10.58	24	63854	184867	90379702
Alopecia	64.47	10.58	160	63718	494911	90069658
Fibromyalgia	63.55	10.58	33	63845	206236	90358333
Joint range of motion decreased	63.09	10.58	10	63868	135633	90428936
Therapeutic product effect decreased	60.26	10.58	64	63814	277507	90287062
Abdominal discomfort	60.03	10.58	157	63721	477171	90087398
Malignant mediastinal neoplasm	59.91	10.58	26	63852	1382	90563187
Synovitis	58.15	10.58	89	63789	329663	90234906
Swelling	56.46	10.58	133	63745	418925	90145644
Hip fracture	56.28	10.58	91	63787	32986	90531583
Hypercholesterolaemia	55.64	10.58	4	63874	100888	90463681
Headache	54.67	10.58	882	62996	861864	89702705
Femur fracture	53.09	10.58	107	63771	45975	90518594
Intentional product use issue	52.93	10.58	45	63833	216847	90347722
Blood cholesterol increased	50.95	10.58	43	63835	207969	90356600
Product use in unapproved indication	50.85	10.58	100	63778	336136	90228433
Bursitis	50.51	10.58	15	63863	131639	90432930
Obesity	48.56	10.58	8	63870	105499	90459070
Toxicity to various agents	48.55	10.58	80	63798	287766	90276803
Device expulsion	48.38	10.58	96	63782	40790	90523779
C3 glomerulopathy	47.53	10.58	13	63865	164	90564405
Grip strength decreased	47.44	10.58	5	63873	92571	90471998
Treatment failure	47.17	10.58	89	63789	303839	90260730
Full blood count decreased	46.90	10.58	79	63799	29610	90534959
Product dose omission issue	46.34	10.58	358	63520	291329	90273240
Fatigue	45.17	10.58	1097	62781	1152926	89411643
Wound infection	44.88	10.58	10	63868	106392	90458177
Unevaluable event	44.78	10.58	111	63767	54737	90509832
Peripheral venous disease	44.40	10.58	4	63874	83917	90480652
Clostridium test positive	44.26	10.58	34	63844	5367	90559202
Presbyacusis	43.54	10.58	27	63851	3015	90561554
Stomatitis	41.26	10.58	82	63796	274616	90289953
Full blood count abnormal	41.00	10.58	84	63794	36513	90528056
Blood pressure measurement	40.75	10.58	14	63864	392	90564177
Dizziness	39.32	10.58	608	63270	588676	89975893
Lower respiratory tract infection	39.24	10.58	73	63805	250586	90313983
Acute kidney injury	39.17	10.58	371	63507	320016	90244553
Mobility decreased	38.39	10.58	74	63804	250660	90313909
Neoplasm skin	37.81	10.58	25	63853	3117	90561452
Nasal congestion	37.74	10.58	137	63741	83277	90481292
Constipation	37.47	10.58	331	63547	280064	90284505
Dehydration	37.43	10.58	250	63628	194197	90370372
Device dislocation	37.34	10.58	74	63804	31408	90533161
Neuropathy peripheral	37.31	10.58	193	63685	136777	90427792
Pleural thickening	37.06	10.58	25	63853	3223	90561346
Lethargy	36.84	10.58	113	63765	63026	90501543
Blood magnesium increased	35.97	10.58	25	63853	3383	90561186
Lung disorder	35.47	10.58	32	63846	149851	90414718
Feeling abnormal	35.24	10.58	220	63658	167015	90397554
Deep vein thrombosis	34.52	10.58	142	63736	91478	90473091
Hypertension	34.27	10.58	186	63692	457346	90107223
Therapy cessation	33.36	10.58	77	63801	36284	90528285
Autoimmune disorder	32.80	10.58	7	63871	76737	90487832
Pleural fibrosis	32.49	10.58	24	63854	3572	90560997
Blood immunoglobulin E increased	32.26	10.58	26	63852	4399	90560170
Contraindicated product administered	31.89	10.58	117	63761	320022	90244547
Psoriatic arthropathy	31.09	10.58	72	63806	228263	90336306
Night sweats	31.06	10.58	27	63851	128739	90435830
Prescribed overdose	30.98	10.58	15	63863	97610	90466959
Live birth	30.36	10.58	9	63869	79098	90485471
Large intestine polyp	29.93	10.58	35	63843	9351	90555218
Arthropathy	29.03	10.58	146	63732	366096	90198473
Hyponatraemia	28.96	10.58	177	63701	133361	90431208
Pelvic kidney	28.96	10.58	8	63870	105	90564464
Cyst	28.77	10.58	46	63832	16515	90548054
Dyspnoea	28.72	10.58	818	63060	880137	89684432
Blood potassium increased	28.60	10.58	52	63826	20697	90543872
Myalgia	28.37	10.58	216	63662	174909	90389660
Exposure during pregnancy	27.99	10.58	81	63797	238329	90326240
Infection	27.77	10.58	146	63732	361948	90202621
Disability	27.68	10.58	77	63801	40668	90523901
Back pain	27.07	10.58	342	63536	316833	90247736
Intentional overdose	26.06	10.58	17	63861	93817	90470752
Urine protein/creatinine ratio increased	25.45	10.58	13	63865	999	90563570
Epigastric discomfort	25.44	10.58	29	63849	7539	90557030
Neutrophil count	25.31	10.58	10	63868	418	90564151
Muscle spasms	25.19	10.58	280	63598	251603	90312966
Sciatica	24.76	10.58	21	63857	101361	90463208
Metabolic encephalopathy	24.63	10.58	27	63851	6725	90557844
Hypophagia	24.50	10.58	68	63810	35869	90528700
Tremor	24.29	10.58	188	63690	152985	90411584
Drug ineffective	24.21	10.58	768	63110	1383530	89181039
Blood lactic acid	24.00	10.58	7	63871	113	90564456
Injury	23.94	10.58	66	63812	197283	90367286
Pulmonary embolism	23.85	10.58	166	63712	130654	90433915
Blepharospasm	23.81	10.58	5	63873	55440	90509129
Plasma cell myeloma	23.75	10.58	73	63805	40755	90523814
Osteopenia	23.67	10.58	51	63827	22951	90541618
Starvation ketoacidosis	23.53	10.58	8	63870	217	90564352
Pain in extremity	23.52	10.58	447	63431	450082	90114487
Overdose	22.88	10.58	48	63830	157661	90406908
Productive cough	22.67	10.58	111	63767	76952	90487617
Myelosuppression	22.67	10.58	5	63873	53586	90510983
Upper gastrointestinal haemorrhage	22.57	10.58	50	63828	22926	90541643
Nail disorder	22.16	10.58	7	63871	59060	90505509
Dysstasia	21.83	10.58	52	63826	25000	90539569
Gastrointestinal haemorrhage	21.75	10.58	123	63755	90125	90474444
Flatulence	21.36	10.58	71	63807	41296	90523273
Urinary tract infection	21.35	10.58	318	63560	305314	90259255
Therapy non-responder	21.21	10.58	40	63838	136664	90427905
Impaired healing	21.14	10.58	89	63789	234110	90330459
Nausea	20.90	10.58	969	62909	1109347	89455222
Thyroiditis acute	20.56	10.58	6	63872	97	90564472
Pelvic pain	20.55	10.58	38	63840	15319	90549250
Hippocampal sclerosis	20.45	10.58	6	63872	99	90564470
Vaginal haemorrhage	20.17	10.58	58	63820	31213	90533356
Atrial fibrillation	20.09	10.58	162	63716	133449	90431120
Therapeutic product effect incomplete	19.87	10.58	70	63808	193826	90370743
Urticaria	19.79	10.58	134	63744	312600	90251969
Lupus-like syndrome	19.79	10.58	5	63873	48841	90515728
Cough	19.56	10.58	367	63511	368595	90195974
Narrow anterior chamber angle	19.43	10.58	5	63873	49	90564520
Deafness neurosensory	19.34	10.58	24	63854	6817	90557752
Intentional product misuse	19.05	10.58	21	63857	89583	90474986
Cerebellar haematoma	19.05	10.58	8	63870	392	90564177
Blindness cortical	19.02	10.58	9	63869	586	90563983
Epilepsy	18.91	10.58	18	63860	82188	90482381
Cerebrovascular accident	18.69	10.58	150	63728	123383	90441186
Dysgeusia	18.65	10.58	80	63798	52480	90512089
Blood potassium decreased	17.99	10.58	74	63804	47653	90516916
Lower limb fracture	17.99	10.58	20	63858	84993	90479576
Lip swelling	17.96	10.58	64	63814	38546	90526023
Parkinsonian rest tremor	17.74	10.58	6	63872	160	90564409
Postural tremor	17.55	10.58	8	63870	478	90564091
Laryngitis	17.36	10.58	7	63871	50746	90513823
Haemorrhoidal haemorrhage	17.22	10.58	20	63858	5303	90559266
Pulmonary fibrosis	17.08	10.58	31	63847	107472	90457097
Nasopharyngitis	17.07	10.58	194	63684	406910	90157659
Restless legs syndrome	16.80	10.58	44	63834	22426	90542143
International normalised ratio increased	16.77	10.58	72	63806	47244	90517325
Chorea	16.67	10.58	13	63865	2097	90562472
Pneumonia	16.64	10.58	577	63301	637482	89927087
Hip arthroplasty	16.05	10.58	18	63860	76190	90488379
Bone pain	15.95	10.58	86	63792	61897	90502672
Liver disorder	15.89	10.58	39	63839	121230	90443339
Injection site haemorrhage	15.88	10.58	50	63828	28268	90536301
Skin depigmentation	15.76	10.58	10	63868	1163	90563406
Eye swelling	15.68	10.58	51	63827	29335	90535234
Melaena	15.60	10.58	57	63821	34740	90529829
Heart rate	15.53	10.58	6	63872	236	90564333
Pulmonary arterial hypertension	15.39	10.58	47	63831	26140	90538429
Product quality issue	15.36	10.58	20	63858	79305	90485264
Gastrointestinal disorder	15.25	10.58	112	63766	256575	90307994
Sleep disorder	15.08	10.58	80	63798	197950	90366619
Knee arthroplasty	15.08	10.58	22	63856	83160	90481409
Drug hypersensitivity	15.03	10.58	233	63645	463376	90101193
Ear infection viral	14.98	10.58	5	63873	128	90564441
AST/ALT ratio abnormal	14.90	10.58	5	63873	130	90564439
Rhinorrhoea	14.90	10.58	110	63768	88206	90476363
Hypomagnesaemia	14.88	10.58	57	63821	35531	90529038
Haemorrhoids	14.84	10.58	47	63831	26655	90537914
Eye pain	14.74	10.58	66	63812	44102	90520467
Blood creatinine increased	14.74	10.58	122	63756	101264	90463305
Psoriasis	14.64	10.58	164	63714	147590	90416979
Vision blurred	14.60	10.58	130	63748	110163	90454406
Dyspnoea exertional	14.53	10.58	94	63784	72194	90492375
Adverse event	14.43	10.58	39	63839	117379	90447190
Skin neoplasm excision	14.33	10.58	11	63867	1735	90562834
Hot flush	14.28	10.58	81	63797	59407	90505162
Hypoaesthesia oral	14.27	10.58	33	63845	15567	90549002
Rheumatoid lung	14.26	10.58	16	63862	4087	90560482
Gait inability	14.26	10.58	54	63824	146402	90418167
Hypervolaemia	14.14	10.58	53	63825	32704	90531865
Megacolon	14.04	10.58	12	63866	2202	90562367
Heart rate abnormal	13.85	10.58	19	63859	5952	90558617
Suicide attempt	13.61	10.58	20	63858	75379	90489190
Withdrawal of life support	13.58	10.58	4	63874	67	90564502
Clostridium difficile infection	13.51	10.58	56	63822	36189	90528380
Uterine leiomyoma	13.44	10.58	26	63852	10838	90553731
New onset diabetes after transplantation	13.39	10.58	5	63873	179	90564390
Faeces discoloured	13.23	10.58	39	63839	21281	90543288
Immunodeficiency	13.18	10.58	7	63871	43227	90521342
Myotonia	13.11	10.58	5	63873	190	90564379
Off label use	12.99	10.58	640	63238	1101612	89462957
Abdominal pain	12.98	10.58	368	63510	395353	90169216
Infected neoplasm	12.89	10.58	6	63872	376	90564193
Keratitis	12.88	10.58	15	63863	3991	90560578
Occult blood positive	12.82	10.58	15	63863	4008	90560561
Influenza like illness	12.80	10.58	99	63779	80512	90484057
Polyhydramnios	12.75	10.58	12	63866	2496	90562073
Abdominal hernia	12.70	10.58	18	63860	5810	90558759
Foot deformity	12.66	10.58	14	63864	59637	90504932
Balance disorder	12.63	10.58	114	63764	96966	90467603
Intracranial haematoma	12.63	10.58	6	63872	394	90564175
Potassium hydroxide preparation positive	12.55	10.58	3	63875	21	90564548
Coeliac disease	12.50	10.58	8	63870	44602	90519967
Skin discolouration	12.44	10.58	63	63815	44252	90520317
Photosensitivity reaction	12.44	10.58	34	63844	17773	90546796
Cardiac failure congestive	12.39	10.58	115	63763	98579	90465990
Temporal lobe epilepsy	12.28	10.58	6	63872	419	90564150
Pain	12.22	10.58	576	63302	995765	89568804
Clostridium difficile colitis	12.19	10.58	44	63834	26662	90537907
Reperfusion arrhythmia	12.12	10.58	5	63873	234	90564335
Hypoxia	12.11	10.58	90	63788	72309	90492260
Laboratory test abnormal	12.10	10.58	60	63818	41794	90522775
White blood cell count decreased	12.10	10.58	175	63703	166934	90397635
Dry eye	12.06	10.58	76	63802	57855	90506714
Liver function test abnormal	12.05	10.58	69	63809	50776	90513793
Rash pruritic	11.98	10.58	99	63779	82115	90482454
Hepatobiliary infection	11.79	10.58	3	63875	28	90564541
Mental impairment	11.75	10.58	32	63846	16688	90547881
Product complaint	11.74	10.58	28	63850	13472	90551097
Haematemesis	11.71	10.58	51	63827	33675	90530894
Urinary incontinence	11.69	10.58	55	63823	37511	90527058
Vulvovaginal mycotic infection	11.61	10.58	18	63860	6296	90558273
Failure to thrive	11.49	10.58	21	63857	8390	90556179
Onychomycosis	11.47	10.58	6	63872	37370	90527199
Rash macular	11.45	10.58	47	63831	30233	90534336
Administration site swelling	11.34	10.58	9	63869	1490	90563079
Dry skin	11.25	10.58	103	63775	87970	90476599
Joint dislocation	11.17	10.58	9	63869	44573	90519996
Thrombosis	11.11	10.58	89	63789	73162	90491407
Cytokine release syndrome	11.07	10.58	3	63875	27970	90536599
Post procedural discharge	11.03	10.58	6	63872	524	90564045
Hyperkalaemia	11.00	10.58	81	63797	64883	90499686
Chromaturia	10.87	10.58	34	63844	19153	90545416
Cellulitis	10.76	10.58	105	63773	91232	90473337
Drug resistance	10.74	10.58	4	63874	30445	90534124
Orthostatic hypotension	10.74	10.58	58	63820	41769	90522800
Aura	10.72	10.58	8	63870	1209	90563360
Skin cancer	10.65	10.58	27	63851	13492	90551077
Hepatotoxicity	10.59	10.58	10	63868	45832	90518737

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Clear cell renal cell carcinoma	88.13	11.20	34	32037	1247	42588017
Off label use	79.00	11.20	234	31837	638101	41951163
Fall	72.95	11.20	359	31712	234161	42355103
Lymphoproliferative disorder	62.69	11.20	36	32035	3271	42585993
Drug ineffective	59.29	11.20	259	31812	629938	41959326
Completed suicide	51.70	11.20	6	32065	96459	42492805
Toxicity to various agents	49.28	11.20	60	32011	229076	42360188
Fatigue	47.86	11.20	519	31552	435122	42154142
Product use in unapproved indication	46.74	11.20	42	32029	184414	42404850
Plasma cell myeloma	41.72	11.20	103	31968	47475	42541789
Full blood count decreased	35.48	11.20	59	32012	20501	42568763
Diarrhoea	35.10	11.20	513	31558	460336	42128928
Asthenia	32.34	11.20	338	31733	280455	42308809
Psoriasis	29.49	11.20	92	31979	48512	42540752
Congenital oesophageal anomaly	29.33	11.20	8	32063	93	42589171
Laboratory test abnormal	28.31	11.20	57	32014	22921	42566343
Intentional product misuse	28.31	11.20	6	32065	61894	42527370
Meconium abnormal	26.44	11.20	7	32064	72	42589192
Dizziness	26.34	11.20	295	31776	248959	42340305
Autoscopy	25.52	11.20	9	32062	255	42589009
Drug interaction	24.18	11.20	111	31960	266888	42322376
Multiple organ dysfunction syndrome	23.49	11.20	23	32048	97012	42492252
White blood cell count decreased	22.98	11.20	152	31919	110244	42479020
Clostridium test positive	22.31	11.20	24	32047	5481	42583783
Product dose omission issue	22.28	11.20	195	31876	154170	42435094
General physical health deterioration	21.93	11.20	51	32020	151195	42438069
Polyhydramnios	21.79	11.20	8	32063	255	42589009
Confusional state	21.79	11.20	207	31864	167390	42421874
Abdominal symptom	21.71	11.20	10	32061	573	42588691
Paraneoplastic rash	20.72	11.20	6	32065	88	42589176
High frequency ablation	20.53	11.20	7	32064	179	42589085
Muscle spasms	20.09	11.20	122	31949	85922	42503342
Intentional overdose	19.76	11.20	7	32064	51449	42537815
Apnoeic attack	19.66	11.20	9	32062	508	42588756
Pneumonia	19.63	11.20	435	31636	421714	42167550
Caput succedaneum	19.42	11.20	6	32065	111	42589153
COVID-19	18.55	11.20	37	32034	115911	42473353
Viral infection	17.96	11.20	47	32024	22436	42566828
Adverse drug reaction	17.54	11.20	65	32006	37369	42551895
Treatment failure	17.40	11.20	13	32058	62611	42526653
Blood magnesium decreased	17.29	11.20	25	32046	7701	42581563
Abdominal pain	17.26	11.20	219	31852	190252	42399012
Cytokine release syndrome	17.20	11.20	6	32065	44521	42544743
Hepatic function abnormal	16.67	11.20	9	32062	51558	42537706
Necrotising enterocolitis neonatal	16.60	11.20	7	32064	324	42588940
Gastrointestinal haemorrhage	15.98	11.20	127	31944	97599	42491665
Lymphoedema	15.69	11.20	19	32052	4929	42584335
Hallucination	15.69	11.20	85	31986	57422	42531842
Renal cell carcinoma	15.60	11.20	20	32051	5497	42583767
Dependence on oxygen therapy	15.35	11.20	6	32065	228	42589036
Constipation	15.30	11.20	188	31883	162103	42427161
Spinal epidural haemorrhage	15.03	11.20	4	32067	42	42589222
Small intestinal obstruction	15.01	11.20	37	32034	17024	42572240
Suicide attempt	14.96	11.20	8	32063	46092	42543172
Swelling face	14.76	11.20	50	32021	27504	42561760
Upper gastrointestinal haemorrhage	14.52	11.20	53	32018	30246	42559018
Haemorrhoids thrombosed	14.39	11.20	6	32065	270	42588994
Weight decreased	14.39	11.20	228	31843	207720	42381544
Agitated depression	14.35	11.20	6	32065	272	42588992
Epileptic encephalopathy	13.97	11.20	6	32065	291	42588973
Hip fracture	13.80	11.20	31	32040	13441	42575823
Microcytic anaemia	13.67	11.20	14	32057	3021	42586243
Haemoglobin decreased	13.60	11.20	156	31915	132315	42456949
Drug ineffective for unapproved indication	13.59	11.20	9	32062	46154	42543110
Iron deficiency anaemia	13.35	11.20	30	32041	13009	42576255
Cytomegalovirus infection	13.10	11.20	4	32067	32302	42556962
Faeces discoloured	13.01	11.20	35	32036	16979	42572285
Malaise	12.98	11.20	228	31843	211928	42377336
Drug resistance	12.58	11.20	5	32066	34243	42555021
Interstitial lung disease	12.57	11.20	25	32046	78437	42510827
Influenza	12.56	11.20	85	31986	62090	42527174
Oedema peripheral	12.55	11.20	157	31914	135919	42453345
Peripheral swelling	12.47	11.20	113	31958	90157	42499107
Unevaluable event	12.45	11.20	55	32016	34233	42555031
Condition aggravated	12.35	11.20	131	31940	260623	42328641
Cardiac flutter	11.75	11.20	11	32060	2129	42587135
Tongue coated	11.70	11.20	6	32065	435	42588829
Monoclonal immunoglobulin increased	11.61	11.20	6	32065	442	42588822
Back pain	11.58	11.20	160	31911	141616	42447648
Femoral neck fracture	11.50	11.20	15	32056	4194	42585070
Testicular haemorrhage	11.46	11.20	5	32066	252	42589012
Pneumonia haemophilus	11.22	11.20	8	32063	1056	42588208

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Swelling face	222.37	10.19	304	80201	92017	110416777
Fall	196.34	10.19	914	79591	602568	109906226
Swollen tongue	184.99	10.19	224	80281	60138	110448656
Completed suicide	147.03	10.19	7	80498	242374	110266420
Dysphonia	137.95	10.19	219	80286	75710	110433084
Hand deformity	130.34	10.19	7	80498	218499	110290295
Haematocrit decreased	116.41	10.19	188	80317	65929	110442865
Drug abuse	114.96	10.19	3	80502	177408	110331386
Duodenal ulcer perforation	111.55	10.19	4	80501	177696	110331098
Glossodynia	111.09	10.19	15	80490	221989	110286805
Haemoglobin decreased	106.49	10.19	410	80095	248317	110260477
Helicobacter infection	102.05	10.19	8	80497	181869	110326925
Infusion related reaction	102.02	10.19	77	80428	381085	110127709
Red blood cell count decreased	99.51	10.19	175	80330	65748	110443046
Folliculitis	98.05	10.19	6	80499	167647	110341147
Angioedema	95.13	10.19	217	80288	98283	110410511
Pericarditis	92.08	10.19	23	80482	219091	110289703
Toxicity to various agents	91.44	10.19	130	80375	480425	110028369
General physical health deterioration	90.24	10.19	106	80399	425189	110083605
Multiple fractures	88.82	10.19	64	80441	8876	110499918
Systemic lupus erythematosus	85.54	10.19	39	80466	254299	110254495
Product use in unapproved indication	73.80	10.19	133	80372	447244	110061550
Clear cell renal cell carcinoma	72.86	10.19	37	80468	2719	110506075
Red blood cell sedimentation rate abnormal	71.91	10.19	89	80416	24420	110484374
Irritable bowel syndrome	71.43	10.19	16	80489	164199	110344595
Sleep disorder due to general medical condition, insomnia type	64.21	10.19	3	80502	105640	110403154
Clostridium test positive	63.37	10.19	57	80448	10836	110497958
Hip fracture	61.93	10.19	100	80405	35051	110473743
Hepatic enzyme increased	61.80	10.19	86	80419	320806	110187988
Product use issue	61.57	10.19	82	80423	311613	110197181
Dizziness	60.66	10.19	775	79730	697418	109811376
Malignant mediastinal neoplasm	59.64	10.19	26	80479	1352	110507442
Rheumatoid factor positive	58.94	10.19	12	80493	131628	110377166
Femur fracture	58.19	10.19	111	80394	44358	110464436
Device expulsion	57.33	10.19	90	80415	30801	110477993
Liver injury	57.27	10.19	19	80486	150394	110358400
Wound	56.95	10.19	52	80453	234385	110274409
Ill-defined disorder	56.01	10.19	22	80483	156831	110351963
Blister	53.39	10.19	52	80453	227324	110281470
Joint range of motion decreased	52.72	10.19	12	80493	121820	110386974
Bursitis	52.00	10.19	15	80490	129903	110378891
Fatigue	51.26	10.19	1201	79304	1214757	109294037
Diarrhoea	50.98	10.19	1135	79370	1138370	109370424
Off label use	50.87	10.19	778	79727	1499407	109009387
Drug ineffective	50.40	10.19	792	79713	1519748	108989046
Fibromyalgia	50.39	10.19	31	80474	170878	110337916
Obesity	49.38	10.19	11	80494	113340	110395454
Intentional product misuse	48.52	10.19	18	80487	132886	110375908
Headache	48.37	10.19	906	79599	881471	109627323
Peripheral venous disease	46.34	10.19	4	80501	84113	110424681
Intentional product use issue	46.18	10.19	68	80437	247838	110260956
Myelosuppression	45.72	10.19	7	80498	94333	110414461
Lymphoproliferative disorder	44.44	10.19	39	80466	7179	110501615
Grip strength decreased	43.66	10.19	4	80501	80170	110428624
Maternal exposure during pregnancy	43.60	10.19	74	80431	254809	110253985
Drug ineffective for unapproved indication	43.53	10.19	169	80336	102669	110406125
Plasma cell myeloma	43.34	10.19	122	80383	62814	110445980
Product dose omission issue	42.70	10.19	389	80116	321393	110187401
Dehydration	42.36	10.19	348	80157	279163	110229631
Hypercholesterolaemia	41.25	10.19	8	80497	90829	110417965
Type 2 diabetes mellitus	41.07	10.19	41	80464	177191	110331603
Dyspnoea	40.84	10.19	1074	79431	1105798	109402996
Full blood count decreased	40.62	10.19	79	80426	32020	110476774
Intentional overdose	40.52	10.19	23	80482	132478	110376316
Stomatitis	40.48	10.19	85	80420	270157	110238637
Alopecia	40.00	10.19	134	80371	364619	110144175
Discomfort	39.88	10.19	59	80446	214648	110294146
Synovitis	39.57	10.19	88	80417	274004	110234790
Treatment failure	38.41	10.19	91	80414	277143	110231651
Upper gastrointestinal haemorrhage	38.38	10.19	101	80404	49995	110458799
Lethargy	38.16	10.19	152	80353	93424	110415370
Disability	37.78	10.19	74	80431	30149	110478645
Acute kidney injury	36.69	10.19	658	79847	634772	109874022
Blood pressure measurement	36.67	10.19	14	80491	516	110508278
Blood immunoglobulin E increased	35.56	10.19	35	80470	7447	110501347
Mobility decreased	35.28	10.19	75	80430	237347	110271447
Presbyacusis	34.64	10.19	23	80482	2796	110505998
Neoplasm skin	34.28	10.19	24	80481	3180	110505614
Blood cholesterol increased	34.10	10.19	51	80454	184734	110324060
Therapy cessation	33.92	10.19	90	80415	44767	110464027
Gastrointestinal haemorrhage	33.61	10.19	221	80284	165297	110343497
Hyponatraemia	32.44	10.19	270	80235	217383	110291411
Therapeutic product effect decreased	32.42	10.19	82	80423	244234	110264560
Wound infection	32.09	10.19	15	80490	96450	110412344
Lung disorder	31.97	10.19	51	80454	179996	110328798
Nasal congestion	31.89	10.19	149	80356	98133	110410661
Device dislocation	31.88	10.19	71	80434	31633	110477161
Autoimmune disorder	31.41	10.19	5	80500	65478	110443316
Night sweats	29.90	10.19	32	80473	133951	110374843
Deep vein thrombosis	29.14	10.19	188	80317	139699	110369095
Metabolic encephalopathy	29.02	10.19	38	80467	11022	110497772
Faeces discoloured	28.66	10.19	71	80434	33877	110474917
Blood potassium increased	28.56	10.19	70	80435	33179	110475615
Pleural thickening	28.55	10.19	22	80483	3377	110505417
Psoriatic arthropathy	28.53	10.19	63	80442	196698	110312096
Hypertension	28.47	10.19	236	80269	509848	109998946
Overdose	28.36	10.19	82	80423	233712	110275082
Blood magnesium increased	28.36	10.19	23	80482	3800	110504994
Cytokine release syndrome	28.35	10.19	8	80497	70298	110438496
Lower respiratory tract infection	28.25	10.19	87	80418	243019	110265775
Swelling	27.89	10.19	146	80359	350895	110157899
Live birth	27.84	10.19	8	80497	69476	110439318
Hypophagia	27.81	10.19	93	80412	52533	110456261
Feeling abnormal	27.36	10.19	225	80280	180486	110328308
Blepharospasm	26.73	10.19	4	80501	54847	110453947
Neutrophil count	25.51	10.19	10	80495	396	110508398
Hypervolaemia	24.90	10.19	86	80419	49374	110459420
International normalised ratio increased	24.89	10.19	127	80378	86645	110422149
Constipation	24.85	10.19	382	80123	357404	110151390
Myalgia	24.66	10.19	259	80246	222122	110286672
Back pain	24.59	10.19	393	80112	370603	110138191
Nail disorder	24.48	10.19	6	80499	57929	110450865
Liver disorder	23.67	10.19	42	80463	142201	110366593
Tremor	23.59	10.19	238	80267	201994	110306800
Bone erosion	23.50	10.19	3	80502	46368	110462426
Abdominal pain	23.45	10.19	513	79992	512476	109996318
Epilepsy	23.42	10.19	23	80482	100186	110408608
Sciatica	23.02	10.19	20	80485	92379	110416415
Suicide attempt	22.73	10.19	25	80480	103369	110405425
Unevaluable event	22.40	10.19	94	80411	59133	110449661
Exposure during pregnancy	22.36	10.19	56	80449	167368	110341426
Pain in extremity	22.22	10.19	487	80018	486631	110022163
Pleural fibrosis	22.07	10.19	21	80484	4287	110504507
Haematemesis	21.72	10.19	93	80412	59015	110449779
Therapeutic response decreased	21.58	10.19	23	80482	96476	110412318
Accidental exposure to product	21.48	10.19	5	80500	50003	110458791
Melaena	21.40	10.19	103	80402	68654	110440140
Large intestine polyp	21.35	10.19	39	80466	15078	110493716
Drug interaction	21.34	10.19	247	80258	499936	110008858
Paraneoplastic rash	20.85	10.19	6	80499	89	110508705
Epigastric discomfort	20.66	10.19	29	80476	8986	110499808
Blood potassium decreased	20.55	10.19	86	80419	54028	110454766
COVID-19	20.55	10.19	100	80405	244960	110263834
Cytomegalovirus infection	20.50	10.19	7	80498	54437	110454357
Abdominal discomfort	20.29	10.19	186	80319	393672	110115122
Starvation ketoacidosis	20.10	10.19	8	80497	330	110508464
Pneumonia	20.05	10.19	804	79701	875910	109632884
Drug resistance	19.97	10.19	8	80497	56366	110452428
Full blood count abnormal	19.69	10.19	87	80418	55965	110452829
Lip swelling	19.62	10.19	81	80424	50586	110458208
Therapeutic product effect incomplete	19.54	10.19	90	80415	223715	110285079
Dyspnoea exertional	19.36	10.19	136	80369	103924	110404870
Cardiac failure congestive	19.22	10.19	181	80324	150819	110357975
Nasopharyngitis	19.14	10.19	189	80316	394172	110114622
Cyst	18.95	10.19	39	80466	16457	110492337
Eye swelling	18.90	10.19	60	80445	32988	110475806
Pelvic pain	18.68	10.19	38	80467	15904	110492890
Hospice care	18.67	10.19	33	80472	12440	110496354
Vaginal haemorrhage	18.64	10.19	50	80455	25024	110483770
Atrial fibrillation	18.64	10.19	252	80253	229390	110279404
Coma	18.55	10.19	36	80469	117833	110390961
Muscle spasms	18.55	10.19	295	80210	277862	110230932
Oedema peripheral	18.45	10.19	339	80166	328321	110180473
Asthenia	18.42	10.19	643	79862	688356	109820438
Dysgeusia	18.40	10.19	100	80405	69885	110438909
Prescribed overdose	18.36	10.19	22	80483	87559	110421235
Onychomycosis	18.35	10.19	3	80502	38528	110470266
Hepatic function abnormal	18.12	10.19	23	80482	89272	110419522
Pulmonary arterial hypertension	17.60	10.19	58	80447	32510	110476284
Therapy non-responder	17.08	10.19	58	80447	157249	110351545
Blood magnesium decreased	17.07	10.19	42	80463	19954	110488840
Haemorrhoidal haemorrhage	17.03	10.19	25	80480	8068	110500726
Chorea	17.01	10.19	16	80489	3219	110505575
Renal cell carcinoma	16.92	10.19	24	80481	7506	110501288
Clostridium difficile infection	16.88	10.19	79	80426	52050	110456744
Dysstasia	16.29	10.19	57	80448	32929	110475865
Sedation	16.27	10.19	16	80489	69667	110439127
Small intestinal obstruction	16.20	10.19	56	80449	32157	110476637
Transfusion	16.20	10.19	48	80457	25424	110483370
Apnoeic attack	16.10	10.19	9	80496	803	110507991
High frequency ablation	16.07	10.19	7	80498	363	110508431
Application site erythema	15.86	10.19	20	80485	5590	110503204
Hepatobiliary infection	15.82	10.19	4	80501	35	110508759
Lupus-like syndrome	15.79	10.19	5	80500	40787	110468007
Mental status changes	15.66	10.19	102	80403	76020	110432774
Abdominal symptom	15.64	10.19	9	80496	849	110507945
Right aortic arch	15.39	10.19	3	80502	6	110508788
Cerebellar haematoma	15.28	10.19	8	80497	626	110508168
Gastric antral vascular ectasia	15.28	10.19	10	80495	1187	110507607
Osteopenia	15.24	10.19	43	80462	22166	110486628
Polyhydramnios	15.13	10.19	12	80493	1921	110506873
Fluid retention	15.13	10.19	119	80386	94188	110414606
Urinary tract infection	15.11	10.19	327	80178	325955	110182839
Multiple organ dysfunction syndrome	15.10	10.19	58	80447	151652	110357142
Drug hypersensitivity	15.09	10.19	236	80269	453854	110054940
Hypomagnesaemia	15.03	10.19	85	80420	60285	110448509
Cerebrovascular accident	14.73	10.19	199	80306	181085	110327709
Flatulence	14.73	10.19	76	80429	52073	110456721
Lower limb fracture	14.68	10.19	20	80485	75328	110433466
Urinary incontinence	14.56	10.19	72	80433	48515	110460279
Skin neoplasm excision	14.47	10.19	12	80493	2046	110506748
Influenza like illness	14.42	10.19	112	80393	88300	110420494
Blood lactic acid	14.36	10.19	7	80498	471	110508323
Iron deficiency anaemia	14.28	10.19	53	80452	31506	110477288
Heart rate	14.24	10.19	6	80499	287	110508507
AST/ALT ratio abnormal	14.13	10.19	5	80500	148	110508646
Pulmonary embolism	14.12	10.19	227	80278	214247	110294547
Cellulitis	14.07	10.19	147	80358	125869	110382925
Gingival erosion	14.04	10.19	5	80500	151	110508643
Viral infection	14.02	10.19	76	80429	53063	110455731
Ear infection viral	13.98	10.19	5	80500	153	110508641
Coeliac disease	13.93	10.19	7	80498	43180	110465614
Complication associated with device	13.90	10.19	39	80466	20034	110488760
Nausea	13.86	10.19	1061	79444	1234629	109274165
Bone pain	13.85	10.19	88	80417	65045	110443749
Haemorrhoids thrombosed	13.69	10.19	6	80499	316	110508478
Confusional state	13.68	10.19	442	80063	468238	110040556
Gait inability	13.66	10.19	52	80453	136324	110372470
Infection	13.51	10.19	184	80321	362016	110146778
Laryngitis	13.49	10.19	7	80498	42404	110466390
Uterine leiomyoma	13.48	10.19	22	80483	7778	110501016
Eye pain	13.45	10.19	72	80433	50027	110458767
Narrow anterior chamber angle	13.39	10.19	5	80500	173	110508621
Vulvovaginal mycotic infection	13.38	10.19	18	80487	5359	110503435
Liver function test abnormal	13.35	10.19	91	80414	68859	110439935
Blindness cortical	13.32	10.19	9	80496	1126	110507668
Abdominal hernia	13.26	10.19	20	80485	6609	110502185
Rash pruritic	13.21	10.19	119	80386	97950	110410844
Failure to thrive	13.20	10.19	30	80475	13544	110495250
Hallucination	13.11	10.19	122	80383	101310	110407484
Anaphylactic shock	13.03	10.19	11	80494	51535	110457259
Occult blood positive	12.87	10.19	21	80484	7424	110501370
Hypoaesthesia oral	12.74	10.19	34	80471	16968	110491826
Transient ischaemic attack	12.72	10.19	85	80420	63897	110444897
Foot deformity	12.69	10.19	10	80495	48470	110460324
Multiple sclerosis relapse	12.68	10.19	71	80434	50169	110458625
Application site rash	12.66	10.19	12	80493	2438	110506356
Productive cough	12.60	10.19	133	80372	114172	110394622
Gastrointestinal disorder	12.56	10.19	114	80391	241838	110266956
Restless legs syndrome	12.55	10.19	43	80462	24583	110484211
Withdrawal of life support	12.51	10.19	4	80501	86	110508708
Cardiogenic shock	12.45	10.19	14	80491	57324	110451470
Parkinsonian rest tremor	12.45	10.19	6	80499	394	110508400
Blood sodium decreased	12.36	10.19	58	80447	38261	110470533
Left atrial dilatation	12.21	10.19	14	80491	3546	110505248
New onset diabetes after transplantation	12.15	10.19	6	80499	415	110508379
Blood albumin decreased	12.15	10.19	46	80459	27606	110481188
Pulmonary hypertension	11.98	10.19	75	80430	55145	110453649
Orthostatic hypotension	11.98	10.19	86	80419	66163	110442631
Inflammation	11.88	10.19	87	80418	193151	110315643
Bronchitis	11.80	10.19	170	80335	156862	110351932
Testicular haemorrhage	11.69	10.19	5	80500	248	110508546
Unresponsive to stimuli	11.65	10.19	83	80422	63707	110445087
Dependence on oxygen therapy	11.64	10.19	7	80498	716	110508078
Rheumatoid lung	11.62	10.19	15	80490	4289	110504505
Postural tremor	11.61	10.19	8	80497	1034	110507760
Product complaint	11.56	10.19	29	80476	13943	110494851
Acute respiratory distress syndrome	11.54	10.19	13	80492	53185	110455609
Heavy menstrual bleeding	11.54	10.19	32	80473	16333	110492461
Altered state of consciousness	11.53	10.19	15	80490	57611	110451183
Peripheral swelling	11.52	10.19	380	80125	403654	110105140
Sleep disorder	11.48	10.19	91	80414	198553	110310241
Injection site haemorrhage	11.40	10.19	51	80454	32977	110475817
Stress	11.33	10.19	39	80466	105309	110403485
Injury	11.29	10.19	79	80426	177186	110331608
Hypoxia	11.29	10.19	144	80361	129371	110379423
Myotonia	11.24	10.19	5	80500	273	110508521
Hepatotoxicity	11.21	10.19	18	80487	63382	110445412
Rebound acid hypersecretion	11.13	10.19	4	80501	124	110508670
Arthropathy	11.11	10.19	145	80360	287377	110221417
Cardio-respiratory arrest	11.07	10.19	45	80460	115791	110393003
Cardiac flutter	11.00	10.19	17	80488	5740	110503054
White blood cell count decreased	10.97	10.19	231	80274	229159	110279635
Neoplasm progression	10.81	10.19	19	80486	64576	110444218
Neuropathy peripheral	10.79	10.19	187	80318	179090	110329704
Haemorrhoids	10.78	10.19	53	80452	35619	110473175
Cholestasis	10.78	10.19	19	80486	64499	110444295
Neurotoxicity	10.68	10.19	9	80496	42198	110466596
Subdural haemorrhage	10.66	10.19	18	80487	6540	110502254
Reperfusion arrhythmia	10.66	10.19	5	80500	309	110508485
Product prescribing error	10.65	10.19	13	80492	51318	110457476
Polyneuropathy	10.61	10.19	5	80500	32007	110476787
Laryngeal pain	10.52	10.19	17	80488	5958	110502836
Application site pruritus	10.46	10.19	14	80491	4146	110504648
Condition aggravated	10.46	10.19	433	80072	734403	109774391
Haemophagocytic lymphohistiocytosis	10.35	10.19	5	80500	31554	110477240
Agitated depression	10.28	10.19	6	80499	581	110508213
Neutropenic sepsis	10.26	10.19	47	80458	30699	110478095
Infected neoplasm	10.20	10.19	6	80499	589	110508205

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	B03AA02	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron bivalent, oral preparations
ATC	B03AD02	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron in combination with folic acid
MeSH PA	D014131	Trace Elements
MeSH PA	D018977	Micronutrients
CHEBI has role	CHEBI:33282	antibacterial agent
CHEBI has role	CHEBI:64946	anti-HIV agent
CHEBI has role	CHEBI:75835	anti-anaemic agent

Related Drugs by ATC class:

B03AA Iron bivalent, oral preparations 8 drugs

ferrous ascorbateferrous aspartateferrous carbonateferrous chlorideferrous gluconateferrous succinateferrous sulfateferrous tartrate

B03AD Iron in combination with folic acid 3 drugs

ferrous gluconateferrous sulfatefolic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Contraception	indication	13197004
Anemia of prematurity	indication	47100003	DOID:11243
Megaloblastic anemia due to folate deficiency	indication	85649008	DOID:14026
Iron deficiency anemia	indication	87522002
Acne vulgaris	indication	88616000
Pregnancy, function	indication	289908002
Breastfeeding (mother)	indication	413712001
Amenorrhea	off-label use	14302001	DOID:13938
Female hypogonadism syndrome	off-label use	16041008
Polycystic ovaries	off-label use	69878008
Endometriosis	off-label use	129103003
Dysmenorrhea	off-label use	266599000
Abnormal uterine bleeding unrelated to menstrual cycle	off-label use	312984006
Menorrhagia	off-label use	386692008
Prevention of Fetal Neural Tube Defects during Pregnancy	off-label use
Heart valve disorder	contraindication	368009	DOID:4079
Peptic ulcer	contraindication	13200003	DOID:750
Hypercholesterolemia	contraindication	13644009
Constipation	contraindication	14760008	DOID:2089
Primary hyperoxaluria	contraindication	17901006	DOID:2977
Hyperphosphatemia	contraindication	20165001	DOID:0050459
Myocardial infarction	contraindication	22298006	DOID:5844
Gastroenteritis	contraindication	25374005	DOID:2326
Hypervitaminosis D	contraindication	27712000	DOID:9971
Sarcoidosis	contraindication	31541009	DOID:11335
Dehydration	contraindication	34095006
Depressive disorder	contraindication	35489007
Migraine	contraindication	37796009	DOID:6364
Hypertensive disorder	contraindication	38341003	DOID:10763
Hemosiderosis	contraindication	39011001	DOID:12119
Disorder of gallbladder	contraindication	39621005	DOID:0060262
Hypokalemia	contraindication	43339004
Body fluid retention	contraindication	43498006
Thrombosis of retinal vein	contraindication	46085004
Gastrectomy	contraindication	53442002
Hyperlipidemia	contraindication	55822004	DOID:1168
Benign mammary dysplasia	contraindication	57993004
Leber's optic atrophy	contraindication	58610003	DOID:705
Obstructive hyperbilirubinemia	contraindication	59848001
Hemolytic anemia	contraindication	61261009	DOID:583
Thrombophlebitis	contraindication	64156001	DOID:3875
Ulcerative colitis	contraindication	64766004	DOID:8577
Intermenstrual bleeding - irregular	contraindication	64996003
Hypercalcemia	contraindication	66931009	DOID:12678
Hyperparathyroidism	contraindication	66999008	DOID:13543
Diabetes mellitus	contraindication	73211009	DOID:9351
Hyperglycemia	contraindication	80394007	DOID:4195
Atrophic gastritis	contraindication	84568007	DOID:8929
Kidney disease	contraindication	90708001	DOID:557
Malignant neoplasm of liver	contraindication	93870000	DOID:3571
Kidney stone	contraindication	95570007
Anemia due to enzyme deficiency	contraindication	111577008
Hb SS disease	contraindication	127040003	DOID:10923
Deep venous thrombosis	contraindication	128053003
Liver function tests abnormal	contraindication	166603001
Angina pectoris	contraindication	194828000
Osteolysis	contraindication	203522001
Cerebrovascular accident	contraindication	230690007
Pulmonary thromboembolism	contraindication	233935004
Disease of liver	contraindication	235856003	DOID:409
Cholestasis of pregnancy	contraindication	235888006
Endometrial carcinoma	contraindication	254878006	DOID:2871
Hypertriglyceridemia	contraindication	302870006
Arteriosclerosis obliterans	contraindication	361133006	DOID:5160
Malignant tumor of cervix	contraindication	363354003	DOID:4362
Thromboembolic disorder	contraindication	371039008
Cardiovascular event risk	contraindication	395112001
Diverticular disease	contraindication	397881000
Hemochromatosis	contraindication	399187006	DOID:2352
Disorder of coronary artery	contraindication	414024009
Obesity	contraindication	414916001	DOID:9970
Estrogen receptor positive tumor	contraindication	416053008
Porphyria	contraindication	418470004
Hypertensive urgency	contraindication	443482000
Carcinoma of female breast	contraindication	447782002
Smokes tobacco daily	contraindication	449868002
Nonspecific Abnormal Papanicolaou Smear of Cervix	contraindication
Repeated Blood Transfusions	contraindication
Major Surgery with Prolonged Post-Operative Immobilization	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4017694	VUID
N0000146068	NUI
D01194	KEGG_DRUG
4017630	VANDF
4017694	VANDF
4028811	VANDF
C0060276	UMLSCUI
CHEBI:31607	CHEBI
CHEMBL1200640	ChEMBL_ID
DB14491	DRUGBANK_ID
C031621	MESH_SUPPLEMENTAL_RECORD_UI
R5L488RY0Q	UNII
6433164	PUBCHEM_CID
24941	RXNORM
4723	MMSL
4919	MMSL
6955	MMSL
d03920	MMSL
000833	NDDF
387289009	SNOMEDCT_US
52108005	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
BACMIN	HUMAN PRESCRIPTION DRUG LABEL	19	0682-3001	TABLET, COATED	27 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
O-Cal Prenatal Vitamin	HUMAN PRESCRIPTION DRUG LABEL	16	0813-0202	TABLET	15 mg	ORAL	UNAPPROVED DRUG OTHER	6 sections
PRENATAL PLUS	HUMAN PRESCRIPTION DRUG LABEL	15	10544-549	TABLET, FILM COATED	27 mg	ORAL	unapproved drug other	8 sections
Se-Natal 19	HUMAN PRESCRIPTION DRUG LABEL	15	13925-116	TABLET	29 mg	ORAL	unapproved drug other	15 sections
Se-Natal 19 Chewable	HUMAN PRESCRIPTION DRUG LABEL	14	13925-117	TABLET, CHEWABLE	29 mg	ORAL	unapproved drug other	16 sections
Se-Tan PLUS	HUMAN PRESCRIPTION DRUG LABEL	13	13925-118	CAPSULE, GELATIN COATED	162 mg	ORAL	unapproved drug other	18 sections
PRENATAL PLUS	HUMAN PRESCRIPTION DRUG LABEL	15	17856-0668	TABLET, FILM COATED	27 mg	ORAL	UNAPPROVED DRUG OTHER	6 sections
C-Nate DHA	HUMAN PRESCRIPTION DRUG LABEL	13	23359-105	CAPSULE, GELATIN COATED	28 mg	ORAL	unapproved drug other	15 sections
Prenatal Plus Vitamins	HUMAN PRESCRIPTION DRUG LABEL	15	39328-106	TABLET	27 mg	ORAL	UNAPPROVED DRUG OTHER	7 sections
PNV-Select	HUMAN PRESCRIPTION DRUG LABEL	18	42192-320	TABLET, FILM COATED	27 mg	ORAL	unapproved drug other	10 sections
PNV-DHA	HUMAN PRESCRIPTION DRUG LABEL	10	42192-321	CAPSULE, GELATIN COATED	27 mg	ORAL	unapproved drug other	11 sections
PNV-DHA	HUMAN PRESCRIPTION DRUG LABEL	8	42192-323	CAPSULE, GELATIN COATED	27 mg	ORAL	unapproved drug other	11 sections
PNV-Omega	HUMAN PRESCRIPTION DRUG LABEL	13	42192-332	CAPSULE, GELATIN COATED	28 mg	ORAL	unapproved drug other	12 sections
PNV Prenatal VitaminPlus Vitamin A	HUMAN PRESCRIPTION DRUG LABEL	12	44946-1046	TABLET	27 mg	ORAL	UNAPPROVED DRUG OTHER	9 sections
Prenatal Vitamins Plus Low Iron	HUMAN PRESCRIPTION DRUG LABEL	15	50090-0616	TABLET	27 mg	ORAL	UNAPPROVED DRUG OTHER	8 sections
PNV Prenatal Plus Multivitamin	HUMAN PRESCRIPTION DRUG LABEL	15	50090-0617	TABLET	27 mg	ORAL	Unapproved drug other	9 sections
Concept OB	HUMAN PRESCRIPTION DRUG LABEL	15	52747-620	CAPSULE	42.50 mg	ORAL	unapproved drug other	13 sections
Concept DHA	HUMAN PRESCRIPTION DRUG LABEL	15	52747-621	CAPSULE, LIQUID FILLED	17.50 mg	ORAL	unapproved drug other	7 sections
Integra F	HUMAN PRESCRIPTION DRUG LABEL	5	52747-711	CAPSULE	62.50 mg	ORAL	unapproved drug other	14 sections
Integra Plus	HUMAN PRESCRIPTION DRUG LABEL	10	52747-712	CAPSULE	62.50 mg	ORAL	unapproved drug other	12 sections
M-Natal Plus	HUMAN PRESCRIPTION DRUG LABEL	14	58657-170	TABLET	27 mg	ORAL	unapproved drug other	7 sections
M-Natal Plus	HUMAN PRESCRIPTION DRUG LABEL	14	58657-170	TABLET	27 mg	ORAL	unapproved drug other	7 sections
Finazol	HUMAN PRESCRIPTION DRUG LABEL	24	59088-008	TABLET	18 mg	ORAL	unapproved drug other	13 sections
Prenatol-M	HUMAN PRESCRIPTION DRUG LABEL	20	59088-009	TABLET	27 mg	ORAL	unapproved drug other	13 sections
Boostervite	HUMAN PRESCRIPTION DRUG LABEL	16	59088-022	TABLET	18 mg	ORAL	unapproved drug other	15 sections
PureVit DualFe Plus	HUMAN PRESCRIPTION DRUG LABEL	13	59088-112	CAPSULE	53 mg	ORAL	unapproved drug other	12 sections
Vitalux	HUMAN PRESCRIPTION DRUG LABEL	20	59088-139	TABLET	27 mg	ORAL	unapproved drug other	13 sections
Vitrexyl plus Iron	HUMAN PRESCRIPTION DRUG LABEL	18	59088-165	TABLET	27 mg	ORAL	unapproved drug other	13 sections
Prenatrix	HUMAN PRESCRIPTION DRUG LABEL	20	59088-166	TABLET	27 mg	ORAL	unapproved drug other	13 sections
Vitrexate FE	HUMAN PRESCRIPTION DRUG LABEL	18	59088-168	TABLET	27 mg	ORAL	unapproved drug other	13 sections