macrogol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4253 25322-68-3

Description:

MoleculeDescription

Synonyms:

  • polyethylene glycol
  • polyethylene glycol 3350
  • polyethylene glycol 400
  • polyethylene glycol 300
  • macrogol
  • macrogol 4000
  • Molecular weight:
  • Formula: (C2H4O)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
10 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 13, 1984 FDA BRAINTREE
Sept. 21, 2018 PMDA EA Pharma Co., Ltd.

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 299.22 9.95 685 61313 185023 50358103
Infective pulmonary exacerbation of cystic fibrosis 201.90 9.95 124 61874 7785 50535341
Contraindicated product administered 156.26 9.95 6 61992 148952 50394174
Rheumatoid arthritis 126.65 9.95 45 61953 202505 50340621
Synovitis 126.54 9.95 6 61992 123859 50419267
Drug ineffective 116.82 9.95 563 61435 818770 49724356
Systemic lupus erythematosus 113.82 9.95 18 61980 140604 50402522
Macular degeneration 112.79 9.95 112 61886 14276 50528850
Treatment failure 106.16 9.95 20 61978 137617 50405509
Drug intolerance 106.02 9.95 69 61929 219035 50324091
Maternal exposure during pregnancy 106.01 9.95 32 61966 159746 50383380
Arthropathy 105.91 9.95 31 61967 157875 50385251
Hand deformity 101.87 9.95 5 61993 100194 50442932
Completed suicide 86.42 9.95 27 61971 131862 50411264
Abdominal pain 76.33 9.95 523 61475 235705 50307421
Glossodynia 73.35 9.95 25 61973 115544 50427582
Pericarditis 71.11 9.95 7 61991 78682 50464444
Joint swelling 68.79 9.95 122 61876 245164 50297962
Swelling 67.80 9.95 88 61910 200784 50342342
Urinary tract infection 67.68 9.95 488 61510 223532 50319594
Therapeutic product effect decreased 66.91 9.95 42 61956 136008 50407118
Exposure during pregnancy 65.79 9.95 33 61965 120982 50422144
Dehydration 65.24 9.95 363 61635 152086 50391040
Febrile neutropenia 62.37 9.95 261 61737 97406 50445720
Drug hypersensitivity 57.58 9.95 140 61858 250870 50292256
Mental status changes 56.21 9.95 132 61866 36140 50506986
Plasma cell myeloma 54.11 9.95 119 61879 31203 50511923
Discomfort 53.92 9.95 33 61965 108347 50434779
Wound 52.93 9.95 32 61966 105762 50437364
Infusion related reaction 52.49 9.95 79 61919 169478 50373648
Alopecia 45.63 9.95 151 61847 244896 50298230
Lower respiratory tract infection 43.31 9.95 32 61966 95169 50447957
Arthralgia 42.55 9.95 339 61659 438363 50104763
Abdominal distension 42.06 9.95 189 61809 72714 50470412
Intestinal obstruction 41.95 9.95 97 61901 26286 50516840
Toxicity to various agents 41.61 9.95 128 61870 212371 50330755
Intentional overdose 38.82 9.95 14 61984 62490 50480636
Helicobacter infection 38.77 9.95 7 61991 49695 50493431
Failure to thrive 38.26 9.95 43 61955 6315 50536811
Drug interaction 37.84 9.95 122 61876 199499 50343627
Hypersensitivity 37.07 9.95 137 61861 215024 50328102
Small intestinal obstruction 36.00 9.95 68 61930 16000 50527126
Nausea 34.86 9.95 1119 60879 704279 49838847
Pneumonia 34.58 9.95 653 61345 377748 50165378
Sepsis 33.09 9.95 277 61721 132648 50410478
Asthenia 31.02 9.95 556 61442 318486 50224640
Fall 30.59 9.95 578 61420 334354 50208772
Aplastic anaemia 30.15 9.95 42 61956 7661 50535465
Nasopharyngitis 29.95 9.95 128 61870 192799 50350327
Acute respiratory failure 28.69 9.95 89 61909 28693 50514433
Eye irritation 28.34 9.95 64 61934 17076 50526050
Full blood count decreased 27.98 9.95 75 61923 22271 50520855
Vomiting 27.88 9.95 750 61248 460008 50083118
Hepatic enzyme increased 26.69 9.95 83 61915 137297 50405829
Abortion spontaneous 26.55 9.95 9 61989 41763 50501363
Abdominal discomfort 26.27 9.95 171 61827 231470 50311656
Disease progression 25.59 9.95 203 61795 95663 50447463
Condition aggravated 25.41 9.95 237 61761 296821 50246305
Off label use 25.32 9.95 419 61579 474007 50069119
Hospice care 24.91 9.95 33 61965 5739 50537387
Respiratory distress 24.78 9.95 88 61910 30401 50512725
Deep vein thrombosis 24.01 9.95 163 61835 73141 50469985
Hyponatraemia 23.73 9.95 200 61798 95939 50447187
Drug abuse 23.68 9.95 23 61975 59823 50483303
Foetal exposure during pregnancy 23.29 9.95 3 61995 27356 50515770
Product odour abnormal 22.78 9.95 15 61983 1062 50542064
Injection site pain 22.33 9.95 66 61932 110958 50432168
Pulmonary embolism 22.22 9.95 206 61792 101498 50441628
Blood potassium decreased 22.22 9.95 97 61901 36848 50506278
Foreign body sensation in eyes 21.90 9.95 18 61980 1793 50541333
White blood cell count decreased 21.42 9.95 228 61770 116494 50426632
Hypoxia 21.34 9.95 121 61877 51002 50492124
Psoriatic arthropathy 21.13 9.95 16 61982 47016 50496110
Blister 20.87 9.95 46 61952 85372 50457754
Hypophagia 20.82 9.95 78 61920 27650 50515476
Peritonitis bacterial 20.66 9.95 27 61971 4634 50538492
Death 20.31 9.95 532 61466 324847 50218279
Gastrointestinal motility disorder 19.80 9.95 26 61972 4483 50538643
Rhinovirus infection 19.74 9.95 23 61975 3511 50539615
C-reactive protein increased 19.57 9.95 32 61966 66442 50476684
Platelet count decreased 19.54 9.95 199 61799 100527 50442599
Ill-defined disorder 19.40 9.95 23 61975 54631 50488495
Colitis 19.37 9.95 96 61902 38433 50504693
Adenocarcinoma of colon 19.14 9.95 18 61980 2144 50540982
Noninfectious peritonitis 19.04 9.95 7 61991 135 50542991
Flatulence 19.00 9.95 79 61919 29379 50513747
Fumbling 18.85 9.95 7 61991 139 50542987
Hip fracture 18.69 9.95 72 61926 25859 50517267
Impaired healing 18.38 9.95 36 61962 69750 50473376
Instillation site pain 18.32 9.95 12 61986 842 50542284
Cystic fibrosis 18.32 9.95 20 61978 2844 50540282
Malnutrition 18.29 9.95 46 61952 13143 50529983
Oedema peripheral 18.14 9.95 283 61715 157678 50385448
Suicide attempt 18.12 9.95 22 61976 51710 50491416
Injection site pruritus 17.84 9.95 14 61984 40397 50502729
Injection site reaction 17.81 9.95 21 61977 50011 50493115
Musculoskeletal stiffness 17.70 9.95 89 61909 128392 50414734
Venous pressure jugular increased 17.67 9.95 10 61988 539 50542587
Rash 17.63 9.95 405 61593 437066 50106060
Seizure 17.49 9.95 221 61777 117653 50425473
Carbon dioxide decreased 17.49 9.95 16 61982 1841 50541285
Lethargy 17.45 9.95 112 61886 49320 50493806
Pseudohyponatraemia 17.38 9.95 5 61993 42 50543084
Device expulsion 16.99 9.95 7 61991 28815 50514311
Atelectasis 16.84 9.95 55 61943 18215 50524911
Therapeutic product effect incomplete 16.58 9.95 57 61941 91458 50451668
Decubitus ulcer 16.51 9.95 36 61962 9382 50533744
Neuropathy peripheral 16.37 9.95 186 61812 96571 50446555
Product taste abnormal 16.36 9.95 15 61983 1730 50541396
Hospitalisation 15.54 9.95 139 61859 67798 50475328
Blood sodium decreased 15.47 9.95 59 61939 21088 50522038
Neutrophil count decreased 15.46 9.95 103 61895 45923 50497203
Salivary gland enlargement 15.44 9.95 8 61990 361 50542765
Blood calcium decreased 15.34 9.95 58 61940 20648 50522478
Urticaria 15.00 9.95 95 61903 129466 50413660
Impaired gastric emptying 14.91 9.95 33 61965 8685 50534441
Product use issue 14.66 9.95 115 61883 149360 50393766
Hyponatraemic seizure 14.54 9.95 8 61990 408 50542718
Urinary retention 14.43 9.95 67 61931 26123 50517003
Pleural effusion 14.42 9.95 158 61840 81296 50461830
Rectal prolapse 14.42 9.95 14 61984 1735 50541391
Injection site swelling 14.38 9.95 18 61980 41755 50501371
Hepatotoxicity 13.94 9.95 8 61990 27218 50515908
Embolism 13.80 9.95 28 61970 6940 50536186
Large intestinal obstruction 13.77 9.95 14 61984 1835 50541291
Inflammation 13.61 9.95 31 61967 56881 50486245
Hepatic function abnormal 13.59 9.95 12 61986 32669 50510457
Encephalopathy 13.55 9.95 79 61919 33632 50509494
Atrial fibrillation 13.53 9.95 187 61811 101558 50441568
Staphylococcal infection 13.38 9.95 82 61916 35534 50507592
Neurogenic bladder 13.37 9.95 17 61981 2840 50540286
Injection site erythema 13.36 9.95 47 61951 74889 50468237
Liver injury 13.12 9.95 7 61991 24799 50518327
Infection 13.10 9.95 142 61856 172812 50370314
Intentional self-injury 13.01 9.95 6 61992 23106 50520020
Sulphaemoglobinaemia 12.97 9.95 3 61995 9 50543117
Kyphosis 12.93 9.95 15 61983 2280 50540846
Product complaint 12.89 9.95 37 61961 11429 50531697
Hip arthroplasty 12.86 9.95 11 61987 30418 50512708
Distal intestinal obstruction syndrome 12.70 9.95 7 61991 358 50542768
Respiratory failure 12.70 9.95 169 61829 91012 50452114
Streptococcal bacteraemia 12.65 9.95 12 61986 1446 50541680
Back pain 12.36 9.95 355 61643 219675 50323451
Proctalgia 12.25 9.95 22 61976 4981 50538145
Drug resistance 12.23 9.95 4 61994 18985 50524141
Calculus bladder 12.22 9.95 8 61990 561 50542565
Urinary tract infection enterococcal 12.22 9.95 15 61983 2419 50540707
Haemorrhoids 12.21 9.95 51 61947 19002 50524124
Unmasking of previously unidentified disease 12.16 9.95 9 61989 769 50542357
Pregnancy 12.13 9.95 11 61987 29566 50513560
Creatinine renal clearance decreased 12.08 9.95 37 61961 11844 50531282
Carbohydrate antigen 125 increased 12.05 9.95 15 61983 2452 50540674
Anxiety 11.82 9.95 293 61705 177313 50365813
Psoriasis 11.82 9.95 44 61954 68956 50474170
Orthostatic hypotension 11.79 9.95 69 61929 29412 50513714
Knee arthroplasty 11.77 9.95 16 61982 35830 50507296
Reticulocyte count increased 11.76 9.95 9 61989 809 50542317
Biliary dyskinesia 11.66 9.95 15 61983 2535 50540591
Balance disorder 11.62 9.95 135 61863 70455 50472671
Weight decreased 11.62 9.95 354 61644 220891 50322235
Hypercalcaemia 11.61 9.95 58 61940 23294 50519832
Incorrect product administration duration 11.48 9.95 31 61967 9244 50533882
Pneumonia aspiration 11.40 9.95 71 61927 30933 50512193
Visceral pain 11.30 9.95 3 61995 18 50543108
Erythema 11.17 9.95 120 61878 146294 50396832
Lung adenocarcinoma stage I 11.16 9.95 3 61995 19 50543107
Escherichia urinary tract infection 11.16 9.95 33 61965 10362 50532764
Faecaloma 11.15 9.95 26 61972 7082 50536044
Compression fracture 11.02 9.95 23 61975 5814 50537312
Toxic epidermal necrolysis 10.99 9.95 6 61992 20986 50522140
Listeraemia 10.98 9.95 4 61994 75 50543051
Blood cholesterol increased 10.97 9.95 33 61965 55182 50487944
Anal incontinence 10.96 9.95 35 61963 11455 50531671
Red blood cell sedimentation rate increased 10.85 9.95 12 61986 29404 50513722
Atrial enlargement 10.83 9.95 6 61992 310 50542816
Pustule 10.80 9.95 10 61988 1168 50541958
Fibrinolysis 10.78 9.95 3 61995 22 50543104
Irritable bowel syndrome 10.76 9.95 30 61968 51411 50491715
Diverticulum 10.74 9.95 33 61965 10581 50532545
Decreased appetite 10.69 9.95 322 61676 200601 50342525
Tremor 10.69 9.95 199 61799 114704 50428422
Sedation complication 10.55 9.95 29 61969 8737 50534389
Dysphagia 10.52 9.95 143 61855 77375 50465751
Enterovirus infection 10.47 9.95 8 61990 717 50542409
Cognitive disorder 10.46 9.95 91 61907 44032 50499094
Adverse event 10.33 9.95 24 61974 43739 50499387
Cardiomyopathy 10.21 9.95 42 61956 15544 50527582
Early satiety 10.03 9.95 8 61990 764 50542362
Pelvic fracture 10.01 9.95 34 61964 11486 50531640
Denture wearer 10.00 9.95 5 61993 209 50542917

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 169.58 10.31 469 44825 113691 29415542
Infective pulmonary exacerbation of cystic fibrosis 114.83 10.31 87 45207 6149 29523084
Toxicity to various agents 108.42 10.31 66 45228 173595 29355638
Appendicolith 95.50 10.31 62 45232 3418 29525815
Drug interaction 83.56 10.31 108 45186 197277 29331956
Urinary tract infection 78.01 10.31 266 45028 72088 29457145
Completed suicide 72.34 10.31 24 45270 90222 29439011
Abdominal distension 70.34 10.31 191 45103 45720 29483513
Abdominal pain 64.78 10.31 391 44903 134966 29394267
Plasma cell myeloma 59.46 10.31 157 45137 36958 29492275
Appendicitis 58.97 10.31 70 45224 8709 29520524
Drug ineffective 55.56 10.31 328 44966 362842 29166391
Febrile neutropenia 54.80 10.31 326 44968 111914 29417319
Sepsis 46.31 10.31 375 44919 142307 29386926
Dehydration 45.96 10.31 317 44977 114431 29414802
Ocular procedural complication 45.42 10.31 12 45282 54 29529179
Vomiting 44.68 10.31 509 44785 211751 29317482
Aplastic anaemia 42.59 10.31 55 45239 7455 29521778
Victim of child abuse 41.63 10.31 22 45272 823 29528410
Fall 38.21 10.31 427 44867 176751 29352482
Interstitial lung disease 35.85 10.31 22 45272 57696 29471537
Drug abuse 34.45 10.31 43 45251 79840 29449393
Hyponatraemia 33.32 10.31 197 45097 67436 29461797
Muscle spasticity 32.90 10.31 39 45255 4844 29524389
Pneumonia 32.11 10.31 677 44617 319495 29209738
Hospice care 30.13 10.31 38 45256 5030 29524203
Cerebral artery thrombosis 30.13 10.31 17 45277 725 29528508
Small intestinal obstruction 29.30 10.31 63 45231 12998 29516235
C-reactive protein increased 28.72 10.31 16 45278 44247 29484986
Nausea 28.44 10.31 610 44684 288645 29240588
Bacteraemia 28.14 10.31 71 45223 16252 29512981
Brain scan abnormal 27.99 10.31 17 45277 833 29528400
Intentional overdose 27.92 10.31 12 45282 38516 29490717
Stress 27.65 10.31 84 45210 21406 29507827
Ascites 27.41 10.31 120 45174 36499 29492734
Renal impairment 27.20 10.31 52 45242 81281 29447952
Hallucination 26.54 10.31 137 45157 44575 29484658
Rhabdomyolysis 25.93 10.31 33 45261 60775 29468458
Failure to thrive 25.81 10.31 44 45250 7640 29521593
Complication associated with device 24.83 10.31 35 45259 5156 29524077
Cardiogenic shock 24.68 10.31 75 45219 19115 29510118
Treatment failure 24.48 10.31 13 45281 36926 29492307
Pneumonia aspiration 24.23 10.31 116 45178 36621 29492612
Suicide attempt 24.12 10.31 11 45283 34099 29495134
Foetal exposure during pregnancy 23.83 10.31 11 45283 33856 29495377
Myocardial infarction 23.61 10.31 88 45206 110208 29419025
Hypophagia 23.57 10.31 78 45216 20794 29508439
Cystic fibrosis 23.53 10.31 19 45275 1473 29527760
Hip fracture 22.84 10.31 50 45244 10442 29518791
Rhinovirus infection 22.19 10.31 26 45268 3190 29526043
Deep vein thrombosis 22.01 10.31 157 45137 57242 29471991
Respiratory distress 20.19 10.31 100 45194 32006 29497227
Therapeutic product effect incomplete 19.31 10.31 19 45275 39286 29489947
Rheumatoid arthritis 18.94 10.31 13 45281 32139 29497094
Mental status changes 18.67 10.31 104 45190 34823 29494410
Decubitus ulcer 18.43 10.31 37 45257 7274 29521959
Contraindicated product administered 18.28 10.31 3 45291 18263 29510970
Ileus 18.25 10.31 56 45238 14346 29514887
Urinary incontinence 18.08 10.31 61 45233 16420 29512813
Back pain 17.85 10.31 237 45057 102047 29427186
Psoriasis 17.73 10.31 14 45280 32213 29497020
Implant site erosion 17.70 10.31 6 45288 71 29529162
Muscular weakness 16.39 10.31 156 45138 61896 29467337
Shunt malfunction 16.22 10.31 7 45287 165 29529068
Aspiration 16.22 10.31 43 45251 10137 29519096
Coma 16.21 10.31 22 45272 39428 29489805
Hypoxia 16.13 10.31 126 45168 47253 29481980
Acute respiratory failure 15.73 10.31 81 45213 26321 29502912
Areflexia 15.35 10.31 20 45274 2734 29526499
Product use in unapproved indication 15.10 10.31 75 45219 86800 29442433
Hepatic function abnormal 15.04 10.31 23 45271 39236 29489997
Hepatocellular injury 14.79 10.31 7 45287 21236 29507997
Sports injury 14.55 10.31 6 45288 126 29529107
Atelectasis 14.34 10.31 54 45240 15338 29513895
Condition aggravated 14.33 10.31 149 45145 146146 29383087
Hypertonia 14.30 10.31 23 45271 3806 29525427
Burkholderia test positive 14.25 10.31 12 45282 987 29528246
Malignant neoplasm progression 14.09 10.31 174 45120 73685 29455548
Chylothorax 14.03 10.31 10 45284 643 29528590
Underdose 13.98 10.31 45 45249 11824 29517409
Metabolic encephalopathy 13.57 10.31 22 45272 3665 29525568
Blood creatine phosphokinase increased 13.56 10.31 26 45268 40618 29488615
Unresponsive to stimuli 13.55 10.31 75 45219 25051 29504182
Epidural lipomatosis 13.26 10.31 10 45284 701 29528532
Renal failure 13.22 10.31 117 45177 118482 29410751
Cytokine release syndrome 13.04 10.31 47 45247 13072 29516161
Dysphagia 13.01 10.31 135 45159 54791 29474442
Liver disorder 12.96 10.31 14 45280 27735 29501498
Hospitalisation 12.84 10.31 117 45177 45871 29483362
Lower respiratory tract infection 12.80 10.31 13 45281 26489 29502744
Fatigue 12.55 10.31 599 44695 316222 29213011
Drug eruption 12.47 10.31 5 45289 16736 29512497
Flatulence 12.47 10.31 57 45237 17652 29511581
Humerus fracture 12.09 10.31 16 45278 2220 29527013
Encephalopathy 11.95 10.31 85 45209 30958 29498275
Cholestasis 11.92 10.31 11 45283 23451 29505782
Myalgia 11.69 10.31 66 45228 73953 29455280
Anal incontinence 11.63 10.31 29 45265 6586 29522647
Sickle cell anaemia with crisis 11.62 10.31 17 45277 2591 29526642
Premature baby 11.57 10.31 6 45288 17274 29511959
Transfusion reaction 11.56 10.31 10 45284 853 29528380
Faecaloma 11.48 10.31 22 45272 4180 29525053
Tracheostomy malfunction 11.19 10.31 4 45290 56 29529177
Leukopenia 11.18 10.31 45 45249 55158 29474075
Viral diarrhoea 11.14 10.31 5 45289 130 29529103
Overdose 11.13 10.31 74 45220 79745 29449488
Cerebral infarction 10.93 10.31 13 45281 24662 29504571
Facial paralysis 10.88 10.31 36 45258 9593 29519640
Gastric hypomotility 10.87 10.31 4 45290 61 29529172
Drug hypersensitivity 10.80 10.31 61 45233 68345 29460888
Pruritus 10.64 10.31 121 45173 116728 29412505
Crowned dens syndrome 10.64 10.31 3 45291 18 29529215
Blood pressure decreased 10.58 10.31 35 45259 45442 29483791
Encopresis 10.57 10.31 5 45289 147 29529086
Implant site swelling 10.48 10.31 4 45290 68 29529165
Chronic sinusitis 10.44 10.31 13 45281 1698 29527535
Confusional state 10.44 10.31 263 45031 127614 29401619
Medical device site pain 10.37 10.31 4 45290 70 29529163
Perirectal abscess 10.37 10.31 12 45282 1453 29527780

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 291.25 9.84 803 83216 228534 64186179
Infective pulmonary exacerbation of cystic fibrosis 285.88 9.84 183 83836 11613 64403100
Completed suicide 154.39 9.84 50 83969 224364 64190349
Drug ineffective 145.88 9.84 583 83436 839664 63575049
Febrile neutropenia 140.19 9.84 549 83470 187108 64227605
Toxicity to various agents 120.91 9.84 179 83840 363334 64051379
Synovitis 114.89 9.84 3 84016 99087 64315626
Contraindicated product administered 112.58 9.84 7 84012 107822 64306891
Rheumatoid arthritis 112.26 9.84 37 83982 164257 64250456
Abdominal pain 107.74 9.84 736 83283 311639 64103074
Appendicolith 104.91 9.84 62 83957 3407 64411306
Drug interaction 103.12 9.84 197 83822 361886 64052827
Abdominal distension 101.29 9.84 315 83704 95679 64319034
Urinary tract infection 101.26 9.84 580 83439 231016 64183697
Dehydration 100.16 9.84 551 83468 216212 64198501
Sepsis 92.41 9.84 564 83455 229777 64184936
Aplastic anaemia 78.85 9.84 94 83925 13826 64400887
Treatment failure 76.86 9.84 28 83991 116788 64297925
Plasma cell myeloma 74.52 9.84 177 83842 45898 64368815
Maternal exposure during pregnancy 68.33 9.84 20 83999 95864 64318849
Drug hypersensitivity 67.10 9.84 130 83889 237685 64177028
Hand deformity 65.73 9.84 4 84015 62767 64351946
Mental status changes 64.76 9.84 201 83818 60961 64353752
Hyponatraemia 64.43 9.84 371 83648 147968 64266745
Drug intolerance 63.94 9.84 91 83928 187901 64226812
Failure to thrive 61.82 9.84 72 83947 10332 64404381
Joint swelling 60.52 9.84 118 83901 215264 64199449
Systemic lupus erythematosus 57.52 9.84 15 84004 77597 64337116
Arthropathy 57.52 9.84 44 83975 120923 64293790
Appendicitis 56.98 9.84 79 83940 13490 64401223
Small intestinal obstruction 56.07 9.84 106 83913 23467 64391246
Pneumonia 55.93 9.84 1031 82988 558545 63856168
Vomiting 55.64 9.84 1017 83002 550100 63864613
Therapeutic product effect decreased 54.79 9.84 42 83977 115309 64299404
Exposure during pregnancy 52.15 9.84 18 84001 77657 64337056
Intentional overdose 52.07 9.84 26 83993 89918 64324795
Infusion related reaction 51.70 9.84 84 83935 164383 64250330
Drug abuse 50.24 9.84 59 83960 132315 64282398
Respiratory distress 49.97 9.84 166 83853 52165 64362548
Hospice care 49.08 9.84 55 83964 7570 64407143
Fall 48.44 9.84 787 83232 416039 63998674
Acute respiratory failure 48.21 9.84 159 83860 49775 64364938
Arthralgia 45.71 9.84 363 83656 441897 63972816
Victim of child abuse 44.36 9.84 22 83997 849 64413864
Lower respiratory tract infection 44.24 9.84 35 83984 94579 64320134
Rhinovirus infection 42.38 9.84 46 83973 6110 64408603
Nausea 41.37 9.84 1326 82693 784474 63630239
Deep vein thrombosis 41.12 9.84 256 83763 104926 64309787
Hypophagia 39.07 9.84 127 83892 39460 64375253
Cystic fibrosis 37.43 9.84 33 83986 3401 64411312
Hypoxia 37.29 9.84 219 83800 87930 64326783
Ocular procedural complication 37.19 9.84 16 84003 443 64414270
Intestinal obstruction 36.34 9.84 117 83902 36169 64378544
C-reactive protein increased 36.33 9.84 42 83977 94867 64319846
Glossodynia 35.53 9.84 20 83999 64676 64350037
Ascites 35.13 9.84 167 83852 61834 64352879
Bacteraemia 34.79 9.84 95 83924 26816 64387897
Pericarditis 33.38 9.84 20 83999 62496 64352217
Hypersensitivity 32.77 9.84 138 83881 196314 64218399
Drug resistance 31.99 9.84 4 84015 35098 64379615
Pneumonia aspiration 30.97 9.84 156 83863 59115 64355598
Nasopharyngitis 30.72 9.84 141 83878 195932 64218781
Interstitial lung disease 30.62 9.84 50 83969 97682 64317031
Renal impairment 30.60 9.84 83 83936 134934 64279779
Wound 30.19 9.84 33 83986 76444 64338269
Hospitalisation 29.99 9.84 184 83835 75023 64339690
Alopecia 29.77 9.84 113 83906 165577 64249136
Condition aggravated 29.69 9.84 326 83693 372100 64042613
Injection site pain 29.59 9.84 63 83956 111345 64303368
Atelectasis 29.22 9.84 90 83929 27176 64387537
Suicide attempt 28.74 9.84 30 83989 70977 64343736
Discomfort 28.63 9.84 38 83981 80840 64333873
Folliculitis 28.48 9.84 3 84016 30074 64384639
Disease progression 26.14 9.84 291 83728 141389 64273324
Myocardial infarction 26.12 9.84 119 83900 165702 64249011
Encephalopathy 26.09 9.84 148 83871 58671 64356042
Overdose 26.04 9.84 113 83906 159453 64255260
Hip fracture 25.90 9.84 86 83933 27013 64387700
Psoriatic arthropathy 25.83 9.84 12 84007 43269 64371444
Product odour abnormal 25.75 9.84 17 84002 1136 64413577
Brain scan abnormal 25.55 9.84 17 84002 1151 64413562
Off label use 25.18 9.84 630 83389 632176 63782537
Carbon dioxide decreased 25.06 9.84 25 83994 3010 64411703
Dysphagia 24.79 9.84 230 83789 106582 64308131
Death 24.62 9.84 812 83207 481893 63932820
Cerebral artery thrombosis 24.60 9.84 16 84003 1043 64413670
Coma 24.58 9.84 48 83971 87567 64327146
Seizure 24.37 9.84 328 83691 166564 64248149
Pleural effusion 24.29 9.84 262 83757 126297 64288416
Cardiogenic shock 24.25 9.84 95 83924 32332 64382381
Rhabdomyolysis 24.25 9.84 52 83967 91674 64323039
Pulmonary embolism 24.06 9.84 294 83725 146062 64268651
Respiratory failure 24.04 9.84 318 83701 160865 64253848
Hepatic function abnormal 24.03 9.84 29 83990 64284 64350429
Therapeutic product effect incomplete 23.91 9.84 63 83956 103419 64311294
Swelling 22.90 9.84 119 83900 160099 64254614
Asthenia 22.84 9.84 724 83295 427320 63987393
Lethargy 22.57 9.84 167 83852 72427 64342286
Helicobacter infection 22.33 9.84 11 84008 38351 64376362
Urinary incontinence 21.67 9.84 99 83920 36052 64378661
Injection site erythema 21.45 9.84 37 83982 70763 64343950
Pruritus 21.24 9.84 283 83736 312117 64102596
Liver disorder 21.08 9.84 23 83996 53328 64361385
Psoriasis 20.36 9.84 39 83980 71664 64343049
Injection site pruritus 20.33 9.84 12 84007 37814 64376899
Blood calcium decreased 20.04 9.84 76 83943 25478 64389235
Hepatic enzyme increased 20.01 9.84 94 83925 129849 64284864
Urinary retention 20.00 9.84 121 83898 49080 64365633
White blood cell count decreased 19.77 9.84 302 83717 157535 64257178
Product administered to patient of inappropriate age 19.64 9.84 27 83992 4574 64410139
Hallucination 19.62 9.84 162 83857 72626 64342087
Decubitus ulcer 19.09 9.84 49 83970 13330 64401383
Inflammation 19.00 9.84 35 83984 65265 64349448
Cytokine release syndrome 18.93 9.84 65 83954 20764 64393949
Impaired healing 18.88 9.84 31 83988 60442 64354271
Fumbling 18.77 9.84 7 84012 132 64414581
Unresponsive to stimuli 18.66 9.84 121 83898 50272 64364441
Eye irritation 18.56 9.84 54 83965 15802 64398911
Malnutrition 18.55 9.84 61 83958 19064 64395649
Injection site swelling 18.45 9.84 16 84003 41337 64373376
Peritonitis bacterial 18.29 9.84 38 83981 9005 64405708
Spinal cord compression 17.93 9.84 29 83990 5674 64409039
Ileus 17.76 9.84 68 83951 22898 64391815
Product use in unapproved indication 17.72 9.84 146 83873 176472 64238241
Medical device site pain 17.64 9.84 8 84011 252 64414461
Salivary gland enlargement 17.53 9.84 9 84010 374 64414339
Sports injury 17.52 9.84 7 84012 160 64414553
Blood potassium decreased 17.48 9.84 101 83918 40298 64374415
Injection site reaction 17.48 9.84 21 83998 46643 64368070
Blister 17.43 9.84 51 83968 80916 64333797
Atrial fibrillation 17.26 9.84 316 83703 170773 64243940
Hepatotoxicity 17.19 9.84 16 84003 39946 64374767
Infection 17.13 9.84 156 83863 184724 64229989
Proctalgia 16.76 9.84 33 83986 7526 64407187
Kyphosis 16.68 9.84 18 84001 2375 64412338
Neurogenic bladder 16.61 9.84 22 83997 3597 64411116
Lymphocyte count decreased 16.49 9.84 100 83919 40599 64374114
Erythema 16.42 9.84 160 83859 186910 64227803
Hepatocellular injury 16.27 9.84 21 83998 45214 64369499
Anal incontinence 16.13 9.84 50 83969 15146 64399567
Flatulence 15.98 9.84 90 83929 35576 64379137
Full blood count decreased 15.96 9.84 65 83954 22517 64392196
Hypertonia 15.74 9.84 29 83990 6296 64408417
Product taste abnormal 15.63 9.84 16 84003 1987 64412726
Foreign body sensation in eyes 15.55 9.84 15 84004 1734 64412979
Adenocarcinoma of colon 15.49 9.84 25 83994 4883 64409830
Liver injury 15.39 9.84 10 84009 29922 64384791
Pseudohyponatraemia 15.27 9.84 6 84013 131 64414582
Hyponatraemic seizure 15.27 9.84 9 84010 492 64414221
Sickle cell anaemia with crisis 15.27 9.84 26 83993 5306 64409407
Labelled drug-drug interaction medication error 15.00 9.84 5 84014 22057 64392656
Abortion spontaneous 14.96 9.84 7 84012 25136 64389577
Back pain 14.89 9.84 429 83590 249742 64164971
Anal spasm 14.86 9.84 3 84016 3 64414710
Noninfectious peritonitis 14.83 9.84 7 84012 242 64414471
Non-cardiac chest pain 14.74 9.84 34 83985 8646 64406067
Aspiration 14.74 9.84 52 83967 16833 64397880
Toxic epidermal necrolysis 14.71 9.84 16 84003 37150 64377563
Streptococcal bacteraemia 14.62 9.84 19 84000 3048 64411665
Oedema peripheral 14.61 9.84 368 83651 209949 64204764
Malignant neoplasm progression 14.53 9.84 217 83802 112654 64302059
Urticaria 14.22 9.84 123 83896 147194 64267519
Upper respiratory tract infection 14.10 9.84 151 83868 72634 64342079
Drooling 14.01 9.84 25 83994 5294 64409419
Confusional state 13.97 9.84 442 83577 260702 64154011
Rectal prolapse 13.85 9.84 14 84005 1712 64413001
Drug eruption 13.81 9.84 16 84003 36120 64378593
Cytomegalovirus infection 13.66 9.84 17 84002 37182 64377531
Platelet count decreased 13.65 9.84 300 83719 167411 64247302
Medication error 13.48 9.84 28 83991 49938 64364775
Muscle spasticity 13.42 9.84 50 83969 16619 64398094
Myalgia 13.36 9.84 137 83882 158480 64256233
Incorrect product administration duration 13.16 9.84 35 83984 9723 64404990
Escherichia urinary tract infection 13.14 9.84 40 83979 11997 64402716
Pulmonary function test decreased 12.89 9.84 27 83992 6434 64408279
Red blood cell sedimentation rate increased 12.86 9.84 13 84006 31222 64383491
Epidural lipomatosis 12.84 9.84 10 84009 867 64413846
Cellulitis 12.82 9.84 182 83837 93475 64321238
Sulphaemoglobinaemia 12.79 9.84 3 84016 9 64414704
Pyrexia 12.67 9.84 867 83152 557777 63856936
Rash 12.67 9.84 479 83540 458070 63956643
Carbohydrate antigen 125 increased 12.57 9.84 14 84005 1914 64412799
Ill-defined disorder 12.47 9.84 24 83995 44028 64370685
Faecaloma 12.23 9.84 34 83985 9694 64405019
Shunt malfunction 12.18 9.84 6 84013 228 64414485
Implant site erosion 12.17 9.84 5 84014 123 64414590
Joint stiffness 12.13 9.84 13 84006 30391 64384322
Blood albumin decreased 12.10 9.84 57 83962 21016 64393697
Enterovirus infection 12.03 9.84 12 84007 1445 64413268
Colitis 11.97 9.84 123 83896 58551 64356162
Large intestinal obstruction 11.75 9.84 16 84003 2686 64412027
Clostridium difficile infection 11.70 9.84 84 83935 36079 64378634
Bandaemia 11.53 9.84 7 84012 404 64414309
Product complaint 11.48 9.84 38 83981 11916 64402797
Creatinine renal clearance decreased 11.40 9.84 43 83976 14378 64400335
Hypotension 11.40 9.84 606 83413 380368 64034345
Cholestasis 11.40 9.84 26 83993 44846 64369867
Musculoskeletal stiffness 11.39 9.84 104 83915 123102 64291611
Neutrophil count decreased 11.37 9.84 152 83867 77044 64337669
Leukocytosis 11.26 9.84 86 83933 37654 64377059
Impaired work ability 11.16 9.84 3 84016 15216 64399497
Visceral pain 11.12 9.84 3 84016 18 64414695
Crowned dens syndrome 10.98 9.84 3 84016 19 64414694
Device expulsion 10.95 9.84 7 84012 21129 64393584
Distal intestinal obstruction syndrome 10.95 9.84 8 84011 630 64414083
Rectal stenosis 10.85 9.84 6 84013 290 64414423
Gastrointestinal motility disorder 10.75 9.84 22 83997 5157 64409556
Angina pectoris 10.75 9.84 27 83992 45054 64369659
Blood chloride increased 10.69 9.84 21 83998 4782 64409931
Scoliosis 10.52 9.84 24 83995 6058 64408655
Orthostatic hypotension 10.51 9.84 100 83919 46638 64368075
Instillation site pain 10.50 9.84 8 84011 671 64414042
Pneumonia respiratory syncytial viral 10.39 9.84 11 84008 1420 64413293
Impaired gastric emptying 10.32 9.84 30 83989 8774 64405939
Listeraemia 10.19 9.84 4 84015 87 64414626
Muscular weakness 10.11 9.84 227 83792 127111 64287602
Embolism 10.10 9.84 37 83982 12198 64402515
Torsade de pointes 10.07 9.84 5 84014 17358 64397355
Metabolic encephalopathy 10.04 9.84 28 83991 7997 64406716
Sedation complication 10.02 9.84 33 83986 10321 64404392
Calculus bladder 9.98 9.84 10 84009 1210 64413503
Haemoglobin decreased 9.87 9.84 328 83691 194735 64219978
Granulocytopenia 9.86 9.84 33 83986 10407 64404306

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AD15 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
ATC A06AD65 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D054368 Laxatives
FDA PE N0000009871 Stimulation Large Intestine Fluid/Electrolyte Secretion
FDA MoA N0000010288 Osmotic Activity
FDA EPC N0000175811 Osmotic Laxative

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Constipation indication 14760008 DOID:2089
Tear film insufficiency indication 46152009
Red eye indication 75705005
Incomplete passage of stool indication 249515001
Keratoconjunctivitis sicca off-label use 302896008 DOID:12895
Anuria contraindication 2472002 DOID:2983
Hypocalcemia contraindication 5291005
Hyperkalemia contraindication 14140009
Severe chronic ulcerative colitis contraindication 14311001
Acute vomiting contraindication 23971007
Complete atrioventricular block contraindication 27885002
Toxic megacolon contraindication 28536002 DOID:1770
Hyperthyroidism contraindication 34486009 DOID:7998
Hypertensive disorder contraindication 38341003 DOID:10763
Gastrointestinal ulcer contraindication 40845000
Toxic colitis contraindication 42359007
Hypokalemia contraindication 43339004
Chronic heart failure contraindication 48447003
Disorder of cardiovascular system contraindication 49601007 DOID:1287
Gastrointestinal perforation contraindication 51875005
Paralytic ileus contraindication 55525008 DOID:8442
Perforation of intestine contraindication 56905009 DOID:2074
Congenital myotonia, autosomal dominant form contraindication 57938005
Acute nephropathy contraindication 58574008
Incontinence of feces contraindication 72042002
Diabetes mellitus contraindication 73211009 DOID:9351
Appendicitis contraindication 74400008 DOID:8337
Hyperchloremia contraindication 74450001
Third degree burn injury contraindication 80247002
Hyperglycemia contraindication 80394007 DOID:4195
Intestinal obstruction contraindication 81060008 DOID:8437
Oliguria contraindication 83128009
Hyponatremia contraindication 89627008
Kidney disease contraindication 90708001 DOID:557
Gastrointestinal obstruction contraindication 126765001
Eye infection contraindication 128351009
Seizure disorder contraindication 128613002
Gastroparesis contraindication 235675006
Hyporeninemic hypoaldosteronism contraindication 236464008
Pyloric obstruction contraindication 244815007
Edema contraindication 267038008
Injury of eye region contraindication 282752000
Familial hyperkalemic periodic paralysis contraindication 304737009 DOID:14451
Gastric retention contraindication 307227006
At risk for aspiration contraindication 371736008
Angle-closure glaucoma contraindication 392291006 DOID:13550
Unconscious contraindication 418107008
Severe dehydration contraindication 450316000
Predisposition to Nausea and Vomiting contraindication
Suppression of the Gag Reflex contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
5MG,N/A;N/A,210GM;N/A,0.74GM;N/A,2.86GM;N/A,5.6GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** HALFLYTELY BRAINTREE N021551 July 16, 2010 DISCN FOR SOLUTION, TABLET, DELAYED RELEASE ORAL 7291324 Oct. 22, 2022 GASTROINTESTINAL LAVAGE INDICATED FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10792306 March 9, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9592252 Aug. 11, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10918723 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9326969 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4020355 VUID
N0000148185 NUI
D03370 KEGG_DRUG
4010510 VANDF
4010512 VANDF
4017885 VANDF
4018073 VANDF
4018836 VANDF
4019294 VANDF
4020355 VANDF
4020744 VANDF
4024435 VANDF
4024437 VANDF
CHEBI:46793 CHEBI
P4K PDB_CHEM_ID
CHEMBL1201478 ChEMBL_ID
CHEMBL457299 ChEMBL_ID
CHEMBL1201479 ChEMBL_ID
C000595212 MESH_SUPPLEMENTAL_RECORD_UI
C000595213 MESH_SUPPLEMENTAL_RECORD_UI
C000595211 MESH_SUPPLEMENTAL_RECORD_UI
DB09287 DRUGBANK_ID
174 PUBCHEM_CID
DB11077 DRUGBANK_ID
DB11161 DRUGBANK_ID
1310594 RXNORM
170507 MMSL
5316 MMSL
64169 MMSL
NOCODE MMSL
d05350 MMSL
002459 NDDF
002470 NDDF
006552 NDDF
007839 NDDF
009223 NDDF
009954 NDDF
010266 NDDF
356076006 SNOMEDCT_US
421083001 SNOMEDCT_US
424535007 SNOMEDCT_US
712566007 SNOMEDCT_US
712567003 SNOMEDCT_US
712568008 SNOMEDCT_US
713360008 SNOMEDCT_US
8030004 SNOMEDCT_US
C0032483 UMLSCUI
CHEMBL2108780 ChEMBL_ID
G2M7P15E5P UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Systane Lubricant HUMAN OTC DRUG LABEL 2 0065-0429 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
Systane HUMAN OTC DRUG LABEL 2 0065-0431 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
Systane HUMAN OTC DRUG LABEL 2 0065-0454 GEL 4 mg OPHTHALMIC OTC monograph final 13 sections
Systane Ultra HUMAN OTC DRUG LABEL 2 0065-1431 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
Systane Ultra HUMAN OTC DRUG LABEL 2 0065-1431 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
SystaneULTRA HUMAN OTC DRUG LABEL 2 0065-1432 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 12 sections
SYSTANE HYDRATION PF PRESERVATIVE FREE HUMAN OTC DRUG LABEL 2 0065-1437 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
Systane Ultra Preservative Free HUMAN OTC DRUG LABEL 2 0065-1507 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 12 sections
SYSTANE HYDRATION PF PRESERVATIVE FREE HUMAN OTC DRUG LABEL 2 0065-1510 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
SYSTANE HYDRATION PF PRESERVATIVE FREE HUMAN OTC DRUG LABEL 2 0065-1510 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
GenTeal Tears Gel Drops HUMAN OTC DRUG LABEL 2 0065-8067 GEL 4 mg OPHTHALMIC OTC monograph final 13 sections
Good Sense Clear Lax HUMAN OTC DRUG LABEL 1 0113-0306 POWDER, FOR SOLUTION 17 g ORAL ANDA 16 sections
Good Sense Lubricant Eye HUMAN OTC DRUG LABEL 2 0113-0896 SOLUTION/ DROPS 0.40 g OPHTHALMIC OTC monograph final 13 sections
Good Sense Lubricant Eye HUMAN OTC DRUG LABEL 2 0113-0896 SOLUTION/ DROPS 0.40 g OPHTHALMIC OTC monograph final 13 sections
Basic Care Clearlax HUMAN OTC DRUG LABEL 1 0113-7306 POWDER, FOR SOLUTION 17 g ORAL ANDA 16 sections
smooth lax HUMAN OTC DRUG LABEL 1 0363-0306 POWDER, FOR SOLUTION 17 g ORAL ANDA 16 sections
Smooth LAX HUMAN OTC DRUG LABEL 1 0363-0465 POWDER 17 g TOPICAL ANDA 16 sections
Smooth LAX HUMAN OTC DRUG LABEL 1 0363-0489 POWDER, FOR SOLUTION 17 g ORAL ANDA 10 sections
Walgreens Multi-Symptom Relief Eye Drops HUMAN OTC DRUG LABEL 5 0363-1462 SOLUTION/ DROPS 1 g OPHTHALMIC OTC monograph final 13 sections
Walgreens Sterile Advance Relief Eye Drops HUMAN OTC DRUG LABEL 4 0363-1677 SOLUTION/ DROPS 0.01 mg OPHTHALMIC OTC monograph final 12 sections
Walgreens Eye Drops Advanced Relief 15mL HUMAN OTC DRUG LABEL 4 0363-4547 LIQUID 1 g OPHTHALMIC OTC monograph final 12 sections
Walgreens Lubricant Eye Drops High Performance 15mL and twin pack HUMAN OTC DRUG LABEL 2 0363-4549 LIQUID 0.40 g OPHTHALMIC OTC monograph final 14 sections
Walgreens Lubricant Eye Drops Dry Eye 15mL and twin pack HUMAN OTC DRUG LABEL 2 0363-4551 LIQUID 0.40 g OPHTHALMIC OTC monograph final 13 sections
Lubricant Eye HUMAN OTC DRUG LABEL 2 0363-6451 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 13 sections
Walgreens Lubricant Eye Drops HUMAN OTC DRUG LABEL 2 0363-7220 SOLUTION/ DROPS 0.40 mg OPHTHALMIC OTC monograph final 11 sections
Walgreens Lubricant Eye HUMAN OTC DRUG LABEL 2 0363-7267 SOLUTION/ DROPS 4 mg OPHTHALMIC OTC monograph final 12 sections
Eye Lubricant HUMAN OTC DRUG LABEL 2 0363-8396 LIQUID 4 mg OPHTHALMIC OTC monograph final 12 sections
Industrial Strength Eye Drops HUMAN OTC DRUG LABEL 2 0498-0162 SOLUTION/ DROPS 1 g OPHTHALMIC OTC monograph final 15 sections
rugby PEG 3350 HUMAN OTC DRUG LABEL 1 0536-1052 POWDER, FOR SOLUTION 17 g ORAL ANDA 16 sections
Rugby Lubricating Eye Drops HUMAN OTC DRUG LABEL 2 0536-1219 LIQUID 0.40 g OPHTHALMIC OTC monograph final 11 sections