Stem definition | Drug id | CAS RN |
---|---|---|
antibiotics, produced by Streptomyces strains | 4247 | 1405-10-3 |
Molecule | Description |
---|---|
Synonyms:
|
Aminoglycoside antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C, and acts by inhibiting translation during protein synthesis.
|
Dose | Unit | Route |
---|---|---|
5 | g | O |
1 | g | P |
Property | Value | Reference |
---|---|---|
BA (Bioavailability) | 3 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
March 26, 1957 | FDA | MONARCH PHARMS |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 383.94 | 16.47 | 373 | 11461 | 310314 | 63166874 |
Macular degeneration | 258.42 | 16.47 | 114 | 11720 | 24262 | 63452926 |
Toxic anterior segment syndrome | 96.70 | 16.47 | 28 | 11806 | 1743 | 63475445 |
Type 2 diabetes mellitus | 86.43 | 16.47 | 81 | 11753 | 63787 | 63413401 |
C-reactive protein | 79.33 | 16.47 | 31 | 11803 | 4851 | 63472337 |
Swollen joint count increased | 61.21 | 16.47 | 52 | 11782 | 36002 | 63441186 |
Rheumatic fever | 55.10 | 16.47 | 53 | 11781 | 43058 | 63434130 |
Chronic sinusitis | 48.28 | 16.47 | 30 | 11804 | 12813 | 63464375 |
Lip dry | 47.94 | 16.47 | 32 | 11802 | 15438 | 63461750 |
Helicobacter infection | 46.69 | 16.47 | 71 | 11763 | 92714 | 63384474 |
Deep vein thrombosis postoperative | 46.42 | 16.47 | 28 | 11806 | 11341 | 63465847 |
Sciatica | 45.38 | 16.47 | 43 | 11791 | 34281 | 63442907 |
Blood cholesterol increased | 43.19 | 16.47 | 69 | 11765 | 93963 | 63383225 |
Fibromyalgia | 42.54 | 16.47 | 63 | 11771 | 80357 | 63396831 |
Live birth | 39.52 | 16.47 | 35 | 11799 | 25595 | 63451593 |
Autoimmune disorder | 38.14 | 16.47 | 29 | 11805 | 17148 | 63460040 |
Paraesthesia oral | 37.32 | 16.47 | 30 | 11804 | 19226 | 63457962 |
Hypercholesterolaemia | 36.67 | 16.47 | 31 | 11803 | 21303 | 63455885 |
Prescribed overdose | 36.30 | 16.47 | 38 | 11796 | 34115 | 63443073 |
Procedural pain | 34.34 | 16.47 | 30 | 11804 | 21539 | 63455649 |
Injury | 33.97 | 16.47 | 54 | 11780 | 73193 | 63403995 |
Mobility decreased | 30.74 | 16.47 | 69 | 11765 | 121090 | 63356098 |
Road traffic accident | 29.06 | 16.47 | 35 | 11799 | 36597 | 63440591 |
Rheumatoid factor positive | 28.39 | 16.47 | 54 | 11780 | 84352 | 63392836 |
Sleep disorder due to general medical condition, insomnia type | 27.74 | 16.47 | 41 | 11793 | 52176 | 63425012 |
Lower limb fracture | 27.63 | 16.47 | 28 | 11806 | 24193 | 63452995 |
Infusion related reaction | 27.28 | 16.47 | 104 | 11730 | 245417 | 63231771 |
Duodenal ulcer perforation | 27.15 | 16.47 | 54 | 11780 | 87155 | 63390033 |
Intentional product use issue | 26.16 | 16.47 | 67 | 11767 | 127825 | 63349363 |
Heart sounds | 26.12 | 16.47 | 9 | 11825 | 987 | 63476201 |
Osteoarthritis | 26.11 | 16.47 | 56 | 11778 | 95287 | 63381901 |
Prolonged expiration | 25.28 | 16.47 | 9 | 11825 | 1087 | 63476101 |
Nail bed tenderness | 24.72 | 16.47 | 7 | 11827 | 402 | 63476786 |
Toxicity to various agents | 24.14 | 16.47 | 8 | 11826 | 247242 | 63229946 |
Septic arthritis staphylococcal | 23.71 | 16.47 | 7 | 11827 | 466 | 63476722 |
Facet joint syndrome | 23.71 | 16.47 | 19 | 11815 | 12119 | 63465069 |
Liver injury | 21.95 | 16.47 | 40 | 11794 | 60480 | 63416708 |
Adverse event | 21.22 | 16.47 | 42 | 11792 | 67517 | 63409671 |
Autonomic neuropathy | 21.11 | 16.47 | 8 | 11826 | 1151 | 63476037 |
Swelling | 20.89 | 16.47 | 104 | 11730 | 275274 | 63201914 |
Oedema | 20.85 | 16.47 | 52 | 11782 | 97570 | 63379618 |
Lymphatic disorder | 20.69 | 16.47 | 6 | 11828 | 375 | 63476813 |
Hip arthroplasty | 20.55 | 16.47 | 34 | 11800 | 47612 | 63429576 |
Wheezing | 20.50 | 16.47 | 51 | 11783 | 95544 | 63381644 |
Folliculitis | 20.05 | 16.47 | 42 | 11792 | 70275 | 63406913 |
Psoriatic arthropathy | 19.81 | 16.47 | 49 | 11785 | 91471 | 63385717 |
Vaginal flatulence | 18.52 | 16.47 | 10 | 11824 | 3283 | 63473905 |
Drug interaction | 18.24 | 16.47 | 10 | 11824 | 229121 | 63248067 |
General physical health deterioration | 18.15 | 16.47 | 80 | 11754 | 201322 | 63275866 |
Irritable bowel syndrome | 17.70 | 16.47 | 44 | 11790 | 82368 | 63394820 |
Liver disorder | 17.62 | 16.47 | 34 | 11800 | 53653 | 63423535 |
Lupus vulgaris | 17.61 | 16.47 | 12 | 11822 | 5982 | 63471206 |
Knee arthroplasty | 17.39 | 16.47 | 34 | 11800 | 54172 | 63423016 |
Therapeutic product effect decreased | 16.85 | 16.47 | 76 | 11758 | 193111 | 63284077 |
Therapy non-responder | 16.80 | 16.47 | 41 | 11793 | 75860 | 63401328 |
Product use in unapproved indication | 16.79 | 16.47 | 72 | 11762 | 179008 | 63298180 |
Adverse drug reaction | 16.53 | 16.47 | 42 | 11792 | 79672 | 63397516 |
Depressive symptom | 16.48 | 16.47 | 10 | 11824 | 4092 | 63473096 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 71.99 | 17.38 | 63 | 3634 | 80466 | 34872768 |
Staphylococcal skin infection | 32.11 | 17.38 | 9 | 3688 | 885 | 34952349 |
Staphylococcal scalded skin syndrome | 25.63 | 17.38 | 6 | 3691 | 287 | 34952947 |
Retinitis | 23.75 | 17.38 | 6 | 3691 | 396 | 34952838 |
Renal injury | 19.35 | 17.38 | 13 | 3684 | 11182 | 34942052 |
Mucosal inflammation | 19.17 | 17.38 | 22 | 3675 | 38600 | 34914634 |
Vanishing bile duct syndrome | 18.24 | 17.38 | 6 | 3691 | 1012 | 34952222 |
Multiple organ dysfunction syndrome | 17.45 | 17.38 | 30 | 3667 | 76536 | 34876698 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug hypersensitivity | 250.61 | 14.78 | 272 | 12487 | 298644 | 79432985 |
Toxic anterior segment syndrome | 101.23 | 14.78 | 31 | 12728 | 2733 | 79728896 |
C-reactive protein | 79.69 | 14.78 | 30 | 12729 | 4949 | 79726680 |
Swollen joint count increased | 74.07 | 14.78 | 46 | 12713 | 22881 | 79708748 |
Rheumatic fever | 67.24 | 14.78 | 47 | 12712 | 28478 | 79703151 |
Macular degeneration | 64.70 | 14.78 | 33 | 12726 | 11263 | 79720366 |
Type 2 diabetes mellitus | 52.93 | 14.78 | 55 | 12704 | 57067 | 79674562 |
Injury | 50.29 | 14.78 | 62 | 12697 | 77434 | 79654195 |
Sciatica | 50.18 | 14.78 | 42 | 12717 | 33180 | 79698449 |
Lip dry | 47.44 | 14.78 | 30 | 12729 | 15388 | 79716241 |
Chronic sinusitis | 46.85 | 14.78 | 28 | 12731 | 12998 | 79718631 |
Paraesthesia oral | 46.54 | 14.78 | 33 | 12726 | 20438 | 79711191 |
Deep vein thrombosis postoperative | 43.65 | 14.78 | 25 | 12734 | 10727 | 79720902 |
Rheumatoid factor positive | 39.02 | 14.78 | 48 | 12711 | 59791 | 79671838 |
Procedural pain | 38.67 | 14.78 | 31 | 12728 | 23053 | 79708576 |
Autoimmune disorder | 38.28 | 14.78 | 27 | 12732 | 16585 | 79715044 |
Live birth | 37.57 | 14.78 | 28 | 12731 | 18716 | 79712913 |
Duodenal ulcer perforation | 35.17 | 14.78 | 48 | 12711 | 66163 | 79665466 |
Drug interaction | 34.01 | 14.78 | 12 | 12747 | 415171 | 79316458 |
Road traffic accident | 31.70 | 14.78 | 37 | 12722 | 43627 | 79688002 |
Glossodynia | 31.39 | 14.78 | 58 | 12701 | 103279 | 79628350 |
Helicobacter infection | 28.97 | 14.78 | 45 | 12714 | 69659 | 79661970 |
Sleep disorder due to general medical condition, insomnia type | 28.49 | 14.78 | 35 | 12724 | 43521 | 79688108 |
Lower limb fracture | 26.40 | 14.78 | 25 | 12734 | 23190 | 79708439 |
Hand deformity | 26.29 | 14.78 | 54 | 12705 | 103865 | 79627764 |
Folliculitis | 26.22 | 14.78 | 38 | 12721 | 55342 | 79676287 |
Nail bed tenderness | 25.69 | 14.78 | 7 | 12752 | 407 | 79731222 |
Liver injury | 24.16 | 14.78 | 37 | 12722 | 56577 | 79675052 |
Systemic lupus erythematosus | 23.92 | 14.78 | 57 | 12702 | 121092 | 79610537 |
Heart sounds | 23.73 | 14.78 | 8 | 12751 | 958 | 79730671 |
Pemphigus | 23.16 | 14.78 | 50 | 12709 | 99532 | 79632097 |
Blood cholesterol increased | 22.96 | 14.78 | 45 | 12714 | 83675 | 79647954 |
Psoriatic arthropathy | 22.71 | 14.78 | 43 | 12716 | 77956 | 79653673 |
Vaginal flatulence | 22.31 | 14.78 | 10 | 12749 | 2565 | 79729064 |
Lymphatic disorder | 22.28 | 14.78 | 6 | 12753 | 334 | 79731295 |
Hip arthroplasty | 22.21 | 14.78 | 28 | 12731 | 35728 | 79695901 |
Toxicity to various agents | 22.03 | 14.78 | 21 | 12738 | 421519 | 79310110 |
Swelling | 21.64 | 14.78 | 80 | 12679 | 216631 | 79514998 |
Prolonged expiration | 21.58 | 14.78 | 8 | 12751 | 1263 | 79730366 |
Irritable bowel syndrome | 21.55 | 14.78 | 37 | 12722 | 62204 | 79669425 |
Wound | 21.17 | 14.78 | 53 | 12706 | 116126 | 79615503 |
Septic arthritis staphylococcal | 21.05 | 14.78 | 7 | 12752 | 804 | 79730825 |
Prescribed overdose | 20.93 | 14.78 | 28 | 12731 | 37855 | 79693774 |
Facet joint syndrome | 20.70 | 14.78 | 16 | 12743 | 11286 | 79720343 |
Fibromyalgia | 20.66 | 14.78 | 37 | 12722 | 64303 | 79667326 |
Staphylococcal skin infection | 19.87 | 14.78 | 8 | 12751 | 1576 | 79730053 |
Anti-cyclic citrullinated peptide antibody positive | 19.62 | 14.78 | 42 | 12717 | 83101 | 79648528 |
Wheezing | 18.97 | 14.78 | 51 | 12708 | 116613 | 79615016 |
Liver disorder | 18.75 | 14.78 | 38 | 12721 | 72379 | 79659250 |
Muscle injury | 18.32 | 14.78 | 30 | 12729 | 48531 | 79683098 |
Impaired healing | 18.12 | 14.78 | 42 | 12717 | 87613 | 79644016 |
Knee arthroplasty | 18.08 | 14.78 | 28 | 12731 | 43220 | 79688409 |
Therapy non-responder | 17.75 | 14.78 | 43 | 12716 | 92262 | 79639367 |
Ill-defined disorder | 17.57 | 14.78 | 35 | 12724 | 65840 | 79665789 |
Infusion related reaction | 17.42 | 14.78 | 78 | 12681 | 230159 | 79501470 |
Female genital tract fistula | 16.83 | 14.78 | 11 | 12748 | 5964 | 79725665 |
Staphylococcal scalded skin syndrome | 16.70 | 14.78 | 5 | 12754 | 408 | 79731221 |
Dyspepsia | 16.17 | 14.78 | 46 | 12713 | 108641 | 79622988 |
Maternal exposure during pregnancy | 15.86 | 14.78 | 53 | 12706 | 136485 | 79595144 |
Slow response to stimuli | 15.53 | 14.78 | 7 | 12752 | 1818 | 79729811 |
Autonomic neuropathy | 15.28 | 14.78 | 7 | 12752 | 1888 | 79729741 |
Retinitis | 14.95 | 14.78 | 10 | 12749 | 5633 | 79725996 |
Dry mouth | 14.83 | 14.78 | 39 | 12720 | 87980 | 79643649 |
None
Source | Code | Description |
---|---|---|
ATC | A01AB08 | ALIMENTARY TRACT AND METABOLISM STOMATOLOGICAL PREPARATIONS STOMATOLOGICAL PREPARATIONS Antiinfectives and antiseptics for local oral treatment |
ATC | A07AA01 | ALIMENTARY TRACT AND METABOLISM ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS INTESTINAL ANTIINFECTIVES Antibiotics |
ATC | A07AA51 | ALIMENTARY TRACT AND METABOLISM ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS INTESTINAL ANTIINFECTIVES Antibiotics |
ATC | B05CA09 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Antiinfectives |
ATC | D06AX04 | DERMATOLOGICALS ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE ANTIBIOTICS FOR TOPICAL USE Other antibiotics for topical use |
ATC | J01GB05 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE AMINOGLYCOSIDE ANTIBACTERIALS Other aminoglycosides |
ATC | R02AB01 | RESPIRATORY SYSTEM THROAT PREPARATIONS THROAT PREPARATIONS Antibiotics |
ATC | S01AA03 | SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Antibiotics |
ATC | S02AA07 | SENSORY ORGANS OTOLOGICALS ANTIINFECTIVES Antiinfectives |
ATC | S03AA01 | SENSORY ORGANS OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS ANTIINFECTIVES Antiinfectives |
FDA CS | M0000946 | Aminoglycosides |
FDA EPC | N0000175477 | Aminoglycoside Antibacterial |
MeSH PA | D000900 | Anti-Bacterial Agents |
MeSH PA | D000890 | Anti-Infective Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D011500 | Protein Synthesis Inhibitors |
CHEBI has role | CHEBI:36047 | antibacterial drugs |
CHEBI has role | CHEBI:50904 | alergeno |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Otitis externa | indication | 3135009 | |
Keratitis | indication | 5888003 | DOID:4677 |
Hepatic encephalopathy | indication | 13920009 | DOID:13413 |
Urinary tract infectious disease | indication | 68566005 | |
Blepharoconjunctivitis | indication | 68659002 | DOID:2456 |
Hepatic coma | indication | 72836002 | DOID:12550 |
Corneal abrasion | indication | 85848002 | |
Uveitis | indication | 128473001 | DOID:13141 |
Infective blepharitis | indication | 312219000 | |
Bacterial keratitis | indication | 314557000 | |
Minor Skin Wound Pain | indication | ||
Superficial Ocular Infection | indication | ||
Mastoidectomy Cavity Infections | indication | ||
Preoperative Bowel Preparation | indication | ||
Minor Bacterial Skin Infections | indication | ||
Chronic purulent otitis media | off-label use | 38394007 | DOID:14247 |
Bacterial conjunctivitis | off-label use | 128350005 | DOID:9700 |
Ocular hypertension | contraindication | 4210003 | DOID:9282 |
Hypocalcemia | contraindication | 5291005 | |
Herpes simplex keratitis | contraindication | 9389005 | |
Herpes zoster auricularis | contraindication | 21954000 | DOID:9210 |
Hypovolemia | contraindication | 28560003 | |
Herpes simplex dendritic keratitis | contraindication | 29943008 | |
Fungal infection of eye | contraindication | 31194008 | |
Parkinsonism | contraindication | 32798002 | |
Bullous myringitis | contraindication | 33528003 | DOID:13791 |
Dehydration | contraindication | 34095006 | |
Severe myopia | contraindication | 34187009 | |
Tuberculosis of eye | contraindication | 49107007 | |
Neuromuscular block, function | contraindication | 55394004 | |
Perforation of tympanic membrane | contraindication | 60442001 | |
Tinnitus | contraindication | 60862001 | |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Third degree burn injury | contraindication | 80247002 | |
Open-angle glaucoma | contraindication | 84494001 | DOID:1067 |
Krukenberg spindle | contraindication | 85430004 | |
Ulceration of intestine | contraindication | 85942002 | |
Herpes simplex | contraindication | 88594005 | DOID:8566 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Myasthenia gravis | contraindication | 91637004 | DOID:437 |
Procedure on urinary system | contraindication | 118677009 | |
Open wound | contraindication | 125643001 | |
Gastrointestinal obstruction | contraindication | 126765001 | |
Eye infection | contraindication | 128351009 | |
Hearing disorder | contraindication | 128540005 | |
Bacterial infection of eye | contraindication | 128984004 | |
Tuberculosis of ear | contraindication | 186269001 | |
Toxic nephropathy | contraindication | 236514003 | |
Telangiectasia disorder | contraindication | 247479008 | |
Rupture of bladder | contraindication | 251925007 | |
Injury of eye region | contraindication | 282752000 | |
Pregnancy, function | contraindication | 289908002 | |
Viral eye infection | contraindication | 312132001 | |
Viral ear infection | contraindication | 312137007 | |
Fungal ear infection | contraindication | 312148000 | |
Adrenal cortical hypofunction | contraindication | 386584007 | DOID:10493 |
Vaccinia keratitis | contraindication | 397552005 | |
Vertigo | contraindication | 399153001 | |
Atrophoderma | contraindication | 399979006 | |
Peripheral vascular disease | contraindication | 400047006 | |
Infant Botulism | contraindication | ||
Auditory Neurotoxicity | contraindication | ||
Disorder of the 8th Cranial Nerve | contraindication |
Species | Use | Relation |
---|---|---|
Cats | Bacterial infections | Indication |
Cats | Wound infections | Indication |
Cats | Superficial ocular bacterial infections limited to the conjunctival or the anterior segment of the eye | Indication |
Cattle | Colibacillosis caused by Escherichia coli | Indication |
Dogs | Bacterial infections | Indication |
Dogs | Bacterial diarrhea | Indication |
Dogs | Wound infections | Indication |
Dogs | Superficial ocular bacterial infections limited to the conjunctival or the anterior segment of the eye | Indication |
Goats | Colibacillosis caused by Escherichia coli | Indication |
Horses | Ear and skin conditions caused by organisms | Indication |
Horses | Ear and skin conditions caused by allergy | Indication |
Horses | Superficial dressing applied to minor cuts | Indication |
Horses | Superficial dressing applied to wounds | Indication |
Horses | Superficial dressing applied to lacerations | Indication |
Horses | Superficial dressing applied to abrasions | Indication |
Horses | Superficial dressing for post-surgical application | Indication |
Sheep | Colibacillosis caused by Escherichia coli | Indication |
Swine | Colibacillosis caused by Escherichia coli | Indication |
Turkeys | Control of mortality associated with Escherichia coli | Indication |
Product | Applicant | Ingredients |
---|---|---|
Neo-Cortef with Tetracaine | Zoetis Inc. | 3 |
Neomix 325 Soluble Powder, Neomix AG 325 Soluble Powder | Zoetis Inc. | 1 |
Hydeltrone Ointment | Boehringer lngelheim Animal Health USA Inc. | 2 |
Neo-Delta-Cortef with Tetracaine Ointment | Zoetis Inc. | 3 |
Biosol Sterile Solution, Biosol Sterile Solution 50 mg | Zoetis Inc. | 1 |
Panolog Ointment | Zoetis Inc. | 4 |
Jenomycin Tablets | Intervet Inc. | 2 |
Neo-synalar Cream | Bausch Health US LLC | 2 |
Neo-Predef with Tetracaine Powder | Zoetis Inc. | 3 |
Neo-Predef with Tetracaine Top. Ointment, Tritop Topical Ointment | Zoetis Inc. | 3 |
Neo-Darbazine Spansule Capsule No.1, Neo-Darbazine Spansule Capsule No.3 | Zoetis Inc. | 3 |
Neo Predef Sterile Ointment | Zoetis Inc. | 2 |
Anaprime Ophthalmic Solution | Zoetis Inc. | 3 |
Kymar Ointment Improved | Intervet Inc. | 4 |
Tresaderm Dermatologic Solution | Boehringer lngelheim Animal Health USA Inc. | 3 |
Anaprime Opthakote Ophthalmic | Zoetis Inc. | 3 |
Optiprime Opthakote Ophthalmic Solution | Zoetis Inc. | 2 |
Bacitracin-Neomycin-Polymyxin with Hydrocortisone Acetate Ophthalmic Ointment, Vetropolycin HC Ophthalmic Ointment | Dechra, Ltd. | 4 |
Bac-Neo-Poly Ophthalmic Ointment, Vetropolycin Ophthalmic Ointment | Dechra, Ltd. | 3 |
Mycitracin Sterile Ophthalmic Ointment | Zoetis Inc. | 3 |
Forte Topical Ointment | Zoetis Inc. | 4 |
Cortisporin Veterinary Ophthalmic Ointment | Intervet Inc. | 4 |
Neosporin Ophthalmic Ointment | Intervet Inc. | 3 |
Neo-Delta Cortef Sterile Solution | Zoetis Inc. | 2 |
Neo-Cortef Sterile Ointment | Zoetis Inc. | 2 |
Neo-Terramycin 100/100, Neo-Terramycin 100/100D, Neo-Terramycin 50/50, Neo-Terramycin 50/50D | Phibro Animal Health Corp. | 2 |
Panolog Cream | Zoetis Inc. | 4 |
Neo-Oxy 100/100 MR, Neo-Oxy 50/50 | Pharmgate Inc. | 2 |
DERMA-VET Ointment | Med-Pharmex Inc. | 4 |
Animax Ointment | Fougera Pharmaceuticals Inc. | 4 |
Derma 4 Ointment | Zoetis Inc. | 4 |
Neomix Ag 325 Medicated Premix, Neomix 325 Medicated Premix | Zoetis Inc. | 1 |
Derm-Otic Ointment | Zoetis Inc. | 4 |
Neomycin Sulfate | Zoetis Inc. | 1 |
NeoMed Soluble Powder | Bimeda Animal Health Limited | 1 |
Biosol Liquid | Zoetis Inc. | 1 |
Neomycin Oral Solution | Huvepharma EOOD | 1 |
Neo-Sol 50 | Huvepharma EOOD | 1 |
Neo 200 Oral Solution | Huvepharma EOOD | 1 |
Neosol Soluble Powder | Med-Pharmex Inc. | 1 |
Derma-Vet Cream | Med-Pharmex Inc. | 4 |
Neosol-Oral | Med-Pharmex Inc. | 1 |
Animax Cream | Fougera Pharmaceuticals Inc. | 4 |
Neomycin Sulfate 325 | Sparhawk Laboratories Inc. | 1 |
Neomycin Liquid | Sparhawk Laboratories Inc. | 1 |
Neomycin and Polymyxin B Sulfates, and Bacitracin Zinc Ophthalmic Ointment | Akorn Animal Health Inc. | 3 |
Thiabendazole, Dexamethasone, Neomycin Sulfate Solution | Dechra Veterinary Products LLC | 3 |
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 | Ion channel | IC50 | 6.40 | CHEMBL | |||||
Lecithin retinol acyltransferase | Enzyme | IC50 | 4.83 | CHEMBL | |||||
Menin | Unclassified | Kd | 4.81 | CHEMBL | |||||
Lethal factor | Enzyme | Ki | 6.30 | CHEMBL | |||||
Extracellular calcium-sensing receptor | GPCR | AGONIST | Kd | 4 | IUPHAR |
ID | Source |
---|---|
4018765 | VUID |
N0000178941 | NUI |
D01618 | KEGG_DRUG |
4017501 | VANDF |
4017991 | VANDF |
4018765 | VANDF |
C0027603 | UMLSCUI |
CHEBI:7507 | CHEBI |
NMY | PDB_CHEM_ID |
CHEMBL3989751 | ChEMBL_ID |
CHEMBL3989769 | ChEMBL_ID |
D009355 | MESH_DESCRIPTOR_UI |
DB00994 | DRUGBANK_ID |
709 | IUPHAR_LIGAND_ID |
232 | INN_ID |
I16QD7X297 | UNII |
8378 | PUBCHEM_CID |
7299 | RXNORM |
2184 | MMSL |
35157 | MMSL |
5163 | MMSL |
5164 | MMSL |
d00312 | MMSL |
002775 | NDDF |
002777 | NDDF |
373528008 | SNOMEDCT_US |
70961008 | SNOMEDCT_US |
73093001 | SNOMEDCT_US |
96026000 | SNOMEDCT_US |
CHEMBL3989533 | ChEMBL_ID |
1404-04-2 | SECONDARY_CAS_RN |
55298-68-5 | SECONDARY_CAS_RN |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
MAXITROL | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0065-0631 | OINTMENT | 3.50 mg | OPHTHALMIC | NDA | 18 sections |
MAXITROL | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0078-0771 | OINTMENT | 3.50 mg | OPHTHALMIC | NDA | 18 sections |
MAXITROL | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0078-0771 | OINTMENT | 3.50 mg | OPHTHALMIC | NDA | 18 sections |
MAXITROL | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0078-0771 | OINTMENT | 3.50 mg | OPHTHALMIC | NDA | 18 sections |
Maxitrol | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0078-0792 | SUSPENSION | 3.50 mg | OPHTHALMIC | NDA | 18 sections |
Neomycin Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1177 | TABLET | 500 mg | ORAL | ANDA | 22 sections |
Neomycin Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1177 | TABLET | 500 mg | ORAL | ANDA | 22 sections |
Neomycin Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-1177 | TABLET | 500 mg | ORAL | ANDA | 22 sections |
Good Sense First Aid Antibiotic | HUMAN OTC DRUG LABEL | 3 | 0113-0084 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Good Sense Triple Antibioticand Pain Relief | HUMAN OTC DRUG LABEL | 4 | 0113-0679 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
basic care first aid antibiotic | HUMAN OTC DRUG LABEL | 3 | 0113-0701 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
good sense triple antibiotic | HUMAN OTC DRUG LABEL | 4 | 0113-1140 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Basic Care First Aid Antibiotic Plus Pain Relief | HUMAN OTC DRUG LABEL | 4 | 0113-7679 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
AntibioticMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 0363-0018 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
AntibioticMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 0363-0018 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Triple Antibiotic with Pain ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 4 | 0363-0123 | OINTMENT | 3.50 mg | TOPICAL | OTC MONOGRAPH FINAL | 13 sections |
Triple Antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0179 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Triple Antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0179 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Triple Antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0179 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
triple antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0539 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 15 sections |
triple antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0539 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 15 sections |
triple antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-0539 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 15 sections |
First Aid Antibiotic | HUMAN OTC DRUG LABEL | 4 | 0363-0841 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
First Aid Antibiotic | HUMAN OTC DRUG LABEL | 4 | 0363-0841 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Walgreens Triple Antibiotic | HUMAN OTC DRUG LABEL | 3 | 0363-2016 | OINTMENT | 3.50 mg | TOPICAL | OTC MONOGRAPH FINAL | 14 sections |
Walgreens Kids Multi-Antibiotic with Pain Relief Cream | HUMAN OTC DRUG LABEL | 3 | 0363-2122 | CREAM | 3.50 mg | TOPICAL | OTC monograph not final | 11 sections |
Walgreens Multi-Antibiotic with Pain Relief Cream | HUMAN OTC DRUG LABEL | 3 | 0363-2123 | CREAM | 3.50 mg | TOPICAL | OTC monograph not final | 9 sections |
Triple Antibiotic | HUMAN OTC DRUG LABEL | 4 | 0363-2900 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Triple Antibiotic | HUMAN OTC DRUG LABEL | 4 | 0363-2900 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 13 sections |
Walgreens Maximum Strength Triple Antibiotic With Pain Relief | HUMAN OTC DRUG LABEL | 4 | 0363-7872 | OINTMENT | 3.50 mg | TOPICAL | OTC monograph final | 11 sections |